Spring element for a drug delivery device, use thereof and drug delivery device

A spring element for a drug delivery device is proposed, the spring element comprising multiple windings with two windings being mechanically coupled to each other by a rigid transverse connection. Furthermore, a drug delivery device comprising such a spring element and using such a spring element in a drug delivery device are proposed.

Drug delivery device

The invention relates to a drug delivery device for setting and dispensing a dose of a drug, comprising: a support body having a first end defining a first opening and a second end defining a second opening, the support body configured to retain a syringe barrel sealed by a stopper slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, a needle shield adapted to be coupled to one of the ends of the support body, slidably disposed thereon and keyed to the support body for preventing relative rotation, wherein at least one guiding track is defined on the support body and at least one retaining clip arranged on the needle shield is deflectable by the guiding track, wherein the guiding track is configured such that the retaining clip follows a first path when the needle shield is depressed from an extended position to a retracted position for needle extension and that the retaining clip follows a different second ...

AUTO-INJECTOR

An auto-injector for delivering a liquid medicament comprising: a housing arranged to contain a syringe and a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end intended to be applied against an injection site, wherein the syringe comprises: a plurality of plunger elements arranged along a length of the syringe between the proximal end of the housing and the piston, each of the plurality of plunger elements having a longitudinal axis; and a cord arranged to connect the plurality of plunger elements, wherein the plunger elements are configured to become aligned along their axes to push the piston towards the distal end to displace the medicament when the cord is acted on by a driving force. 1. An auto-injector for delivering a liquid medicament comprising:a housing arranged to contain a syringe and a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end intended to be applied against an injection site, wherein the syringe comprises:a plurality of plunger elements arranged along a length of the syringe between the proximal end of the housing and the piston, each of the plurality of plunger elements having a longitudinal axis; anda cord arranged to connect the plurality of plunger elements,wherein the plunger elements are configured to become aligned along their axes to push the piston towards the distal end to displace the medicament when the cord is acted on by a driving force.2. The auto-injector of claim 1 , wherein each of the plurality of plunger elements comprises a longitudinal hole claim 1 , and the cord is threaded through the longitudinal holes of the plurality of plunger elements to connect the plurality of plunger elements.3. The auto-injector of claim 1 , wherein the plurality of plunger elements are in a stacked arrangement in an initial state.4. The auto-injector of claim 1 , further comprising a driving actuator connected to the cord ...

METHOD OF MANUFACTURING A DRUG DELIVERY DEVICE BODY

The invention relates to a method for manufacturing a drug delivery device body comprising the following steps: 1. A method of manufacturing a drug delivery device body comprising the steps:A) providing a first part of the drug delivery device body with at least one selected area and at least one non-selected area on the surface of the first part of the drug delivery device body, wherein the selected area is a part of the contact area of the first part of the drug delivery device body and a second part of the drug delivery device body which is to be fixed to the first part of the drug delivery device body,B) depositing a layer of an adhesive on the surface of the first part wherein deposition means for selected deposition of the adhesive only in the selected area are provided, andC) joining of the first and the second part of the drug delivery device body so that the layer of the adhesive is arranged in the contact area of the first and the second part of the drug delivery device body only.2. The method according to claim 1 , wherein step B) comprises pad printing of the adhesive.3. The method according to claim 1 , wherein step B) comprises spraying of the adhesive.4. The method according to claim 1 , wherein the adhesive is selected from the group consisting of pressure sensitive adhesives claim 1 , drying adhesives claim 1 , contact adhesives claim 1 , hot melt adhesives and chemical setting adhesives.5. The method according to claim 1 , wherein the means for deposition of the adhesive comprise a mask covering the non-selected area.6. The method according to claim 1 , wherein in step B) a second layer of the adhesive is deposited on a second selected area of the second part of the drug delivery device body claim 1 , wherein the second selected area corresponds to the selected area of the first part of the drug delivery device body.7. The method according to claim 1 , wherein the first or the second part of the drug delivery device body is indicative for the drug ...

Drug delivery device

A drug delivery device for setting and dispensing a dose of a drug is presented having a support body having a first end defining a first opening and a second end defining a second opening and a centered outer indicator ring. A syringe barrel sealed by a stopper is slidably diposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, wherein the syringe barrel is positioned within the support body. A needle shield is adapted to be coupled to one of the ends of the support body and slidably disposed thereon. An outer body is adapted to be coupled to the other end of the support body and slidably disposed thereon, wherein the outer indicator ring limits the movement of the outer body as well as of the needle shield.

Dry shaving apparatus

The invention is directed to a dry shaving apparatus with a housing (1) in which an electric drive mechanism (2) is provided having a drive element (3) for the transmission of a driving motion to at least one reciprocatory cutting element (4), and with at least one shaving head (6) oscillating in a horizontal direction and formed by a shaving head frame (7, 55) in which at least two cooperating cutting elements (4, 5) are provided, wherein the electric drive mechanism (2) is mounted for oscillation in the housing (1) and is adapted to be set in oscillation by the inner forces necessarily occurring in operation of the dry shaving apparatus, and wherein the oscillatory motions of the electric drive mechanism (2) are transmitted to the shaving head (6) in order to set said shaving head in oscillation as well.

Drug delivery device with restricted cap replacement

The present disclosure relates to a drug delivery device that has a housing and a cap. The drug delivery device also has a lock that prevents the cap being fully replaced on the housing after the cap has been removed.

DRUG DELIVERY DEVICE

A drug delivery device comprises an outer housing rollable around a rotation axis and at least one stop member. The stop member protrudes radially from the outer housing of the drug delivery device and is configured to prevent rolling movement of the drug delivery device along a predetermined surface. The outer housing comprises a main housing and a dose member. The dose member is movable with respect to the main housing when setting and/or delivering a dose of a drug. The stop member comprises a first part and a second part, wherein the first part is arranged on the main housing and the second part is arranged on the dose member. 1. A drug delivery device , comprisingan outer housing rollable around a rotation axis and at least one stop member, wherein the stop member protrudes radially from the outer housing of the drug delivery device and wherein the stop member is configured to prevent rolling movement of the drug delivery device along a predetermined surface, wherein the outer housing comprises a main housing and a dose member, wherein the dose member is movable with respect to the main housing when setting and/or delivering a dose of a drug and wherein the stop member comprises a first part and a second part, wherein the first part is arranged on the main housing and the second part is arranged on the dose member.2. The drug delivery device according to claim 1 , wherein the stop member protrudes radially from the outer housing by at least 0.75 mm.3. The drug delivery device according to claim 1 , wherein the stop member extends along the rotation axis by 1.0 cm or less.4. The drug delivery device according to claim 1 , wherein the stop member extends along an outer surface of the outer housing and transversally with respect to the rotation axis by 0.5 cm or less.5. The drug delivery device according to claim 1 , wherein the stop member comprises a surface which faces away from the outer housing of the drug delivery device and wherein said surface is plane.6. ...

Medication Delivery Device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device. 138-. (canceled)39. A method of preventing the setting of a dose of medication which exceeds an amount of medication contained in a medication receptacle of a medication delivery device , the medication delivery device comprisinga piston rod which is moveable in a distal direction for medication delivery, the piston rod comprising a second stop element,a drive device for moving the piston rod in the distal direction for medication delivery, moving a dose limiting member which comprises a first stop element axially in a proximal direction with respect to the piston rod during dose setting, and', 'utilizing the first and second stop elements to stop an axial movement of the dose limiting member in the proximal direction with respect to the piston rod when the first and second stop elements catch,', 'limiting a movement of the dose setting member for increasing a set dose of medication to be delivered, wherein the dose limiting member and the piston rod only interact directly, when the first and second stop elements catch., 'a dose setting member for setting a dose of medication to be delivered, the method comprising the steps of'}40. The method of claim 39 , further comprising the step of engaging the dose limiting member with the dose setting member.41. The method of claim 40 , further comprising the step of utilizing the dose limiting member to stop a movement of the dose setting member for increasing a set dose of medication to be delivered when the axial movement of the dose limiting member is stopped.42. The method of claim 39 , ...

DRUG DELIVERY DEVICE

A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated. 1. A drug delivery device , comprising:a body having a receptacle for a drug;a piston rod in the body, the piston rod being movable relatively to the body and being provided for expelling the drug out of the receptacle, wherein the piston rod comprises an axis and a screw thread;a mechanism provided to drive the piston rod while delivering the drug, the piston rod having a start position with respect to the mechanism prior to delivery of a first portion of the drug;a device for guiding the movement of the piston rod relatively to the body while delivering the drug, the device comprising a reset nut is located coaxially around the piston rod, which passes through a central hole of the reset nut, wherein on an inner sidewall of the hole, there is at least one spline, which engages a groove of the piston rod which runs straight along the piston rod, parallel to the axis of the piston rod;a device for releasing the piston rod from the device for guiding the movement, the device for releasing being provided to enable a reset of the piston rod to the start position; anda drive sleeve having a thread corresponding to the screw thread of the piston rod and engaging the screw thread of the piston rod,wherein the reset of the piston rod to the start position comprises a helical movement of the piston rod relatively to the drive sleeve according to the screw thread of the piston rod.2. The drug delivery device according to claim 1 , wherein the groove of the piston rod is formed on a surface of the ...

Long-hair cutter unit

The invention is directed to a long-hair cutter unit (LHS) for a dry shaving apparatus (TR), with a dimensionally stable cutting comb (11) having one cutting teeth row (17) and at least one bearing surface (110) for at least one engagement surface (120) of an arcuately curved, hardened cutting blade (12) having one cutting teeth row (18) and held in engagement with the cutting comb (11) by a pressure of at least one spring element (19, wherein the curvature of the hardened cutting blade (12) is partially configured by means of a forming process such as to ensure conformance and slidable contact of the engagement surface (120) of the cutting blade (12) with the bearing surface (110) of the cutting comb (11) by means of the partial curvatures as well as their restoring forces under the action of the pressure of the spring element (19).

Dry shaving apparatus

The invention is directed to a dry shaving apparatus with an electric drive mechanism (A) provided in a housing (1) and a housing part (G) in which a removable frame (WR) equipped with at least one cutter element (S) is held by at least one detent mechanism (R), wherein upon release of the removable frame (WR) by the detent mechanism (R) the removable frame (WR) is movably held in a holding position by a retaining device (HV), wherein in said holding position provision is made for at least one distance (W, W1) between a wall of the removable frame (WR) and a wall of the housing part (G), and the removable frame (WR) is adapted to be set in motion by the drive mechanism (A).

INJECTION DEVICE

An injection device comprising: a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end, wherein the distal end is intended to be applied against an injection site; a driving mechanism arranged between the piston and the proximal end of the housing; and a locking mechanism comprising a plate member arranged between the driving mechanism and the piston to retain the driving mechanism to retain the driving mechanism in an initial inactive state in which the driving mechanism cannot be actuated; wherein when the locking mechanism is released, the driving mechanism can be actuated to push the piston towards the distal end of the housing to displace the medicament.

AN INJECTION DEVICE WITH SLIDABLE MEMBER FOR REMOVING A CAP WITH A NEEDLE SHIELD

The present disclosure relates to an injection device. The injection device comprises a cap and a body for holding a syringe that has a needle at one end. The cap is removably attached to the body and has a needle shield to receive the needle. The injection device further comprises an actuator that is slidable relative to the body in the longitudinal direction of the body to urge the needle shield away from the body.

Drug delivery device

A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated by a stop element inhibiting a reversal of the movement of the piston rod when being reset.

Mounting arrangement and coupling assembly for a drug-delivery device

A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element. At least one of the plug element or the side wall of the recess are provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element and the housing part being mechanically coupled to each other.

AN INJECTION DEVICE

An auto-injector device comprises a cap removal mechanism which comprises a retractable component which is slidably mounted within a housing of the device, and a cap-removal actuator to push the retractable component out of the housing to remove a cap from the device; a dispense mechanism which comprises a driving element to expel a medicament from the device; and a dispense button which activates the cap removal mechanism when pressed a first time, engages with the dispense mechanism when released, and activates the dispense mechanism when pressed a second time. The dispense mechanism comprises an engaging element configured to engage with the dispense button when the dispense button has been pressed for a first time and released.

Medication delivery device

A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge.

Auto-Injector

An auto-injector for delivering a liquid medicament includes a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end and a telescopic plunger unit arranged between the piston and the proximal end of the housing, the telescopic plunger unit comprising a telescopic frame and a spring element surrounding a plunger element. The plunger element is fixed to a base of the telescopic plunger unit and the spring element is held in an initial compressed state by a compressive force exerted by the base of the telescopic plunger unit. When the spring element is released, a tapering profile of the telescopic frame is configured to provide varying friction with extension such that resistance to telescopic extension decreases as spring force provided by the spring element decreases with increasing extension of the telescopic plunger unit. 112-. (canceled)13. An auto-injector configured to deliver a liquid medicament , the auto-injector comprising:a housing arranged to contain a syringe, the housing comprising a piston configured to seal the syringe and displace the medicament, the housing having a proximal end and a distal end, wherein the distal end is configured to be applied against an injection site; anda telescopic plunger unit arranged between the piston and the distal end of the housing, the telescopic plunger unit comprising a telescopic frame and a spring element surrounding a plunger element, wherein the plunger element is fixed to a base of the telescopic plunger unit and the spring element is configured to be held in an initial compressed state by a compressive force exerted by the base of the telescopic plunger unit,wherein, when the spring element is released, a tapering profile of the telescopic frame is configured to provide varying friction with extension such that resistance to telescopic extension decreases as spring force provided by the spring element ...

Mounting arrangement and coupling assembly for a drug-delivery device

A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element. At least one of the plug element or the side wall of the recess are provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element and the housing part being mechanically coupled to each other.

PEN CAP

The present invention refers to a pen cap, being capable of covering a distal end of a drug delivery device comprising at least one protruding element located inside the pen cap which prevents that the rim of an outer needle cap, while being a protective casing for the needle at the distal end of the drug delivery device, can get stuck within a part of the pen cap if the user puts the pen cap on the drug delivery device. The inner diameter of the pen cap is reduced by means of the at least one protruding element, such that the inner diameter of the pen cap is smaller than the largest outer diameter of the outer needle cap. Furthermore, the invention relates to a drug delivery device comprising a pen cap with the described protruding elements.

Fixing Means

A fixing means () for a drug delivery device () comprises at least two clip elements () for releasably securing at least one drug delivery device () to said fixing means (), wherein each of the two clip elements () comprises a flexible holding member () and wherein the clip elements () share one flexible holding member () with each other. 1. A fixing means for a drug delivery device , wherein the fixing means comprises at least two clip elements for releasably securing at least one drug delivery device to said fixing means , wherein each of the two clip elements comprises a flexible holding member and wherein the clip elements share one flexible holding member with each other.2. The fixing means of claim 1 , wherein the clip element is configured to encompass the at least one drug delivery device.3. The fixing means of claim 1 , wherein the holding members are arranged to receive and retain the at least one drug delivery device in a holding space extending between each other.4. The fixing means according to claim 1 , wherein the holding member of the clip element is configured to bow radially outwardly with respect to the at least one drug delivery device while introducing the device into or releasing the device from the fixing means.5. The fixing means according to claim claim 1 , wherein the holding members comprise free ends and wherein the distance between the free ends of the holding members is smaller than the diameter of the drug delivery device.6. The fixing means according to claim 1 , wherein the two clip elements are marked differently.7. The fixing means according to claim 1 , wherein the fixing means comprises at least one attaching means for attaching the fixing means to a carry case.8. The fixing means according to claim 7 , wherein the attaching means comprises at least one cut-out.9. The fixing means according to claim 1 , wherein the at least one drug delivery device is a pen-type drug delivery device.10. An assembly comprising a drug delivery ...

Long-hair cutter unit

The invention is directed to a long-hair cutter unit (LHS) for a dry shaving apparatus (TR), with a dimensionally stable cutting comb (11) having one cutting teeth row (17) and at least one bearing surface (110) for at least one engagement surface (120) of an arcuately curved, hardened cutting blade (12) having one cutting teeth row (18) and held in engagement with the cutting comb (11) by a pressure of at least one spring element (19, wherein the curvature of the hardened cutting blade (12) is partially configured by means of a forming process such as to ensure conformance and slidable contact of the engagement surface (120) of the cutting blade (12) with the bearing surface (110) of the cutting comb (11) by means of the partial curvatures as well as their restoring forces under the action of the pressure of the spring element (19).

Electric razor

The invention is directed to a dry shaving apparatus with a housing (1) in which an electric drive mechanism (2) is provided having a drive element (3) for the transmission of a driving motion to at least one reciprocating cutting element (4), and with at least one shaving head (6) mounted on two support arms (28, 29) of a supporting frame (40 for pivotal movement about a pivot axis (Z) within a shaving head frame (7), said shaving head being formed by at least two cooperating cutting elements (4, 5) disposed in the shaving head frame (7), wherein the shaving head (6) is mounted and held for pivotal movement about the pivot axis (Z) by means of a conical bearing (K) acted upon by a spring force of a spring element (50).

ANISOTROPIC CELLULAR ELASTOMERS

Cellular elastomer which is anisotropic, with anisotropy being defined by the compressive modulus in one of three orthogonal directions being greater than that in the other two directions by a factor of at least 1.5.

Drug delivery device and cartridge holder for a drug delivery device

A drug delivery device is provided with a cartridge holder having at least one guide track, and a body having at least one interaction member adapted and arranged to mechanically cooperate with the at least one guide track. The guide track has a first section and a second section, wherein the path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the path defined by the first section with the longitudinal axis is smaller than the angle which is enclosed by the path defined by the second section with the longitudinal axis.

Locking Interface, Cartridge Holder and Drug Delivery Device Comprising a Locking Interface

A locking interface for locking a cartridge holder onto a main body of a drug delivery device comprises a locking member for locking the cartridge holder onto the main body, a user interface operable by a user, a support member, on which the locking member and the user interface are located, wherein the locking interface is configured such that a force needed for unlocking the cartridge holder and the main body is reducible by operating the user interface. 115-. (canceled)16. A locking interface for locking a cartridge holder onto a main body of a drug delivery device , the locking interface comprising:a locking member for locking the cartridge holder onto the main body,a user interface operable by a user,a support member, on which the locking member and the user interface are located, wherein the locking interface is configured such that a force needed for unlocking the cartridge holder from the main body is reducible by operating the user interface.17. The locking interface of claim 16 , comprising a base claim 16 , wherein the support member is resiliently connected to the base.18. The locking interface of claim 17 , wherein the support member is resiliently connected to the base in a hinge region.19. The locking interface of claim 17 , wherein the resilient connection is facilitated by at least one cut-out in the base.20. The locking interface of claim 19 , wherein the cut-out encircles the support member except from the hinge region.21. The locking interface of claim 17 , configured such that by operating the user interface the support member deflects relative to the base.22. The locking interface of claim 16 , wherein the user interface comprises at least one tactile member.23. The locking interface of claim 22 , wherein the tactile member comprises at least one of a rib claim 22 , a knob or a rippled surface.24. The locking interface of claim 17 , wherein the user interface and the locking member are located such on the support member that claim 17 , when the ...

Combination foam

The combination foam comprises a matrix composed of polyurethane foam and foamed particles of thermoplastic polyurethane comprised therein, where matrix and particles are each made up of polyol components and polyisocyanate components, wherein at least 50% by weight of the basic building blocks forming the polyol component of the matrix and particles are identical and at least 50% by weight of the basic building blocks forming the polyisocyanate component of the matrix and particles are identical.

Drive assembly for a drug delivery device and corresponding drug delivery device

A drive assembly for a drug delivery device is disclosed. The drive assembly is connectable with a cartridge holder and comprises a housing, a piston rod, the piston rod being movable in a distal direction for drug delivery, and a guide nut, the guide nut being rotatable relative to the housing around an axis of the assembly and provided for guiding the piston rod. A locking means is provided which is enabled to take an engaged state in which the locking means is engaged with the guide nut in order to prevent rotation of the guide nut and to take a disengaged state in which the locking means is disengaged from the guide nut in order to allow rotation of the guide nut. Moreover, a coupling means is provided, the coupling means being rotatable relative to the housing around the axis of the assembly for interaction with the locking means in order to change between the engaged state and the disengaged state of the locking means.

CELLULAR ELASTOMER WITH LITTLE TENDENCY TOWARD CREEP AT HIGH TEMPERATURES

The present invention relates to cellular polyisocyanate polyaddition products whose density to DIN EN ISO 845 is from 200 to 800 kg/m3, and also to prepolymer composed of at least one diisocyanate (a) and of at least one polyether alcohol (b), where the at least one polyether alcohol (b) comprises the following components: (b1) aliphatic polyether alcohols whose number-average molar mass is from 300 to 1000 g/mol, (b2) aliphatic polyether alcohols whose number-average molar mass is from 2000 to 10 000 g/mol, and (b3) aliphatic polyether alcohols whose number-average molar mass is from 10 000 to 100 000 g/mol, to a process for its production, to a cellular polyisocyanate polyaddition product thus produced, and to its use as damping elements in vehicle construction.

Medication delivery device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in such medication delivery device, in particular in pen-type injectors, preferably having a dose setting member and a drive device enabling the dose setting and the administration of a medicinal product from a multi-dose medication cartridge, to methods using such device, and to methods of manufacturing and assembly of such device.

Drug-Filled Stents to Prevent Vessel Micro-Injuries and Methods of Manufacture Thereof

A stent includes a hollow wire formed into a stent pattern. The hollow wire includes an outer member, a lumen extending longitudinally within the hollow wire, at least one opening extending from an outer surface of the outer member to the lumen, and a surface area component within the hollow wire. The surface area component increases the amount of surface area available for tissue in-growth within the hollow wire. More than one surface area component may be utilized. Each surface area component may be disposed within the lumen or the at least one opening of the hollow wire. A pharmacologically or biologically active agent may be disposed within the lumen. 1. A stent comprising: an outer member;', 'a lumen extending longitudinally within the hollow wire;', 'at least one opening disposed through the outer member to the lumen and defined by a radial surface; and', 'a surface area component disposed within the hollow wire,, 'a hollow wire formed into a stent pattern, wherein the hollow wire includeswherein the surface area component increases the amount of surface available for tissue in-growth within the hollow wire.2. The stent of claim 1 , wherein the surface area component is disposed on an inner surface of the hollow wire defining the lumen.3. The stent of claim 2 , wherein the surface area component extends a full length of the hollow wire.4. The stent of claim 2 , wherein the surface area component is a roughness on the inner surface of the hollow wire defining the lumen.5. The stent of claim 2 , wherein the surface area component is a channel on the inner surface of the hollow wire defining the lumen.6. The stent of claim 2 , wherein the surface area component is a ledge on the inner surface of the hollow wire defining the lumen.7. The stent of claim 2 , wherein the surface area component is a rounded protrusion on the inner surface of the hollow wire defining the lumen.8. The stent of claim 2 , wherein the surface area component is a groove on the inner surface ...

SPRING ELEMENT FOR A DRUG DELIVERY DEVICE, USE THEREOF AND DRUG DELIVERY DEVICE

A spring element for a drug delivery device is proposed, the spring element comprising multiple windings with two windings being mechanically coupled to each other by a rigid transverse connection. Furthermore, a drug delivery device comprising such a spring element and using such a spring element in a drug delivery device are proposed.

Medication delivery device

A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge.

DRUG DELIVERY DEVICE

A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated by a stop element inhibiting a reversal of the movement of the piston rod when being reset. 1. A drug delivery device , comprising:a body having a receptacle for a drug;{'b': '8', 'a piston rod () in the body, the piston rod being movable relatively to the body and being provided for expelling the drug out of the receptacle;'}a mechanism provided to drive the piston rod while delivering the drug, the piston rod having a start position with respect to the mechanism;a device for guiding the movement of the piston rod relatively to the body while delivering the drug;a device for releasing the piston rod from the device for guiding the movement, the device for releasing being provided to enable a reset of the piston rod to the start position; anda stop element provided for inhibiting a movement of the piston rod away from the start position, when the piston rod has been released.2. The drug delivery device according to claim 1 , wherein the stop element is engaged with the body in such a manner that a rotation of the stop element relatively to the body is inhibited.3. The drug delivery device according to claim 1 , further comprising:a groove in the body, the groove guiding the stop element; anda stop of the groove provided for blocking a movement of the stop element opposite to the movement of the piston rod during reset.4. The drug delivery device according to claim 1 , wherein the device for guiding the movement of the piston rod provided to engage the piston rod with the stop element if a ...

Coded cartridge holder system for a fluid delivery device

A coded cartridge holder system is disclosed for use with a cartridge assembly (20) containing a fluid and a delivery device (10), where the system has keyed connectors (5, 5, 6, 6) to prevent accidental attachment of the wrong fluid delivery device (10). The system comprises a coupling (1) attachable to the dose setting portion (12) of the device (10) and keyed to the proximal end of the cartridge holder (14). The cartridge holder (14) may also contain medical coding (27, 28) to correspond to matching coding (27, 28) on the distal end of a cartridge assembly (20).

Water vapor-permeable composite material

A composite material contains a nonwoven layer (i) which contains fibers formed from a first thermoplastic elastomer having meshes with a mesh size in the range from 10 to 100 μm, and a membrane layer (ii) which contains a second thermoplastic elastomer and having a layer thickness of less than 30 μm. The membrane is either pore-free (ii.1) or is porous and has pores with an average pore diameter of less than 2000 nm (ii.2). The membrane (ii) is at least partially in direct contact with the fibers of the nonwoven layer (i) and covers the mesh openings in the nonwoven layer (i) at least partially. The fibers of the first nonwoven layer (i) and the membrane (ii) in the contact area are at least partly joined to one another in an interlocking manner.

Dry shaving apparatus

Dry shaving apparatus comprises a first individual shaving unit (111) having at least two first cutters cooperating together, including a first outer cutter and a first undercutter; at least a second individual shaving unit (112, 113) having at least two second cutters cooperating together including a second outer cutter and a second undercutter; biasing element for the cooperation of the cutters; and at least one drive source coupled with at least one cutter of each individual shaving unit. All cutters of at least the first (111) of the individual shaving units are coupled to the drive source to be driven for cutting and skin agitating purposes and the outer cutter of at least a further one (112, 113) of the individual shaving units is inactive.

MOUNTING ARRANGEMENT AND COUPLING ASSEMBLY FOR A DRUG-DELIVERY DEVICE

A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element. At least one of the plug element or the side wall of the recess are provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element and the housing part being mechanically coupled to each other. 1. A pen-type drug injection device comprising:a housing having a longitudinal axis and a recess with a side wall comprising a deformable protrusion positioned parallel to the longitudinal axis;a hollow cylinder; anda cartridge holder configured to stabilize the hollow cylinder,wherein the hollow cylinder is mechanically coupled within the recess by a force fit contact with the protrusion, where a friction force is caused by a deformation of the protrusion when the hollow cylinder is coupled to the housing.2. The device of where the hollow cylinder is a cartridge configured to hold a plurality of doses of a drug.3. The device of where the recess has a plurality of protrusions.4. The device of where the wherein a longitudinal section of the protrusion has a constant radial distance (R) relative to the longitudinal axis (L).5. The device of where the drug comprises a pharmaceutical formulation containing at least one pharmaceutically active compound claim 2 , wherein in one embodiment the pharmaceutically active compound has a molecular weight up to 1500 Da and/or is a peptide claim 2 , a protein claim 2 , a polysaccharide claim 2 , a vaccine claim 2 , a DNA claim 2 , an RNA claim 2 , an enzyme claim 2 , an antibody claim 2 , a hormone or an oligonucleotide claim 2 , or a mixture of the above-mentioned pharmaceutically active compound.6. The device of where the drug comprises at ...

Drug delivery device

A drug delivery device for setting and dispensing a dose of a drug is presented having a support body having a first end defining a first opening and a second end defining a second opening and a centered outer indicator ring. A syringe barrel sealed by a stopper is slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, wherein the syringe barrel is positioned within the support body. A needle shield is adapted to be coupled to one of the ends of the support body and slidably disposed thereon. An outer body is adapted to be coupled to the other end of the support body and slidably disposed thereon, wherein the outer indicator ring limits the movement of the outer body as well as of the needle shield.

Drug Delivery Device with Restricted Cap Replacement

The present disclosure relates to a drug delivery device that has a housing and a cap. The drug delivery device also has a lock that prevents the cap being fully replaced on the housing after the cap has been removed. 120-. (canceled)21. A drug delivery device comprising a housing , a cap , and a lock that prevents the cap being fully replaced on the housing after the cap has been removed.22. The drug delivery device of claim 21 , wherein the lock comprises a locking member configured to move into a locking position on first removal of the cap from the housing claim 21 , and wherein the locking member is configured to prevent the cap from being fully replaced on the housing when the locking member is in the locking position.23. The drug delivery device of claim 22 , wherein the locking member comprises a resiliently biased member.24. The drug delivery device of claim 22 , wherein the locking member comprises a pre-stressed element.25. The drug delivery device of claim 22 , wherein the locking member is configured to be in a deflected position in which the locking member pushes against a part of the housing prior to first removal of the cap from the housing.26. The drug delivery device of claim 22 , wherein the locking member is integral to the cap and is configured to push against a part of the housing prior to first removal of the cap from the housing.27. The drug delivery device of claim 22 , wherein the locking member is integral to the housing and is configured to push against a part of the cap prior to first removal of the cap from the housing.28. The drug delivery device of claim 22 , wherein the locking member comprises a spring.29. The drug delivery device of claim 28 , wherein the spring is mounted in the cap.30. The drug delivery device of claim 22 , wherein the cap and the housing are arranged such that prior to removal of the cap from the housing claim 22 , the cap and the housing overlap in an overlapping region claim 22 , and wherein the locking member ...

Cellular elastomer with little tendency toward creep at high temperatures

The present invention relates to cellular polyisocyanate polyaddition products whose density to DIN EN ISO 845 is from 200 to 800 kg/m3, and also to prepolymer composed of at least one diisocyanate (a) and of at least one polyether alcohol (b), where the at least one polyether alcohol (b) comprises the following components: (b1) aliphatic polyether alcohols whose number-average molar mass is from 300 to 1000 g/mol, (b2) aliphatic polyether alcohols whose number-average molar mass is from 2000 to 10 000 g/mol, and (b3) aliphatic polyether alcohols whose number-average molar mass is from 10 000 to 100 000 g/mol, to a process for its production, to a cellular polyisocyanate polyaddition product thus produced, and to its use as damping elements in vehicle construction.

Drug-filled stents with filaments for increased lumen surface area and method of manufacture thereof

A stent including a hollow wire formed into a stent pattern. The hollow wire includes an outer member having an outer surface and an inner surface, a lumen extending longitudinally within the hollow wire, at least one opening extending from the outer surface of the outer member to the lumen, and a plurality of filaments extending longitudinally within the lumen. The plurality of filaments increases the amount of surface area available for tissue in-growth within the lumen. Each filament of the plurality of filaments is spaced from adjacent filaments of the plurality of filaments, and the spacing between adjacent filaments of the plurality of filaments is configured to permit tissue in-growth between the adjacent filaments.

Drug delivery device with protective needle cap control and device activation mechanism

A drug delivery device includes an outer body receiving a cartridge with a needle, a needle cap adapted to be coupled to the outer body and to cover the needle and a control mechanism for activating the drug delivery device. The control mechanism includes a control element received within the outer body and axially and/or rotationally movable relative to the outer body between an initial position, a first activating position, and a second activating position. The control element is coupled to the needle cap and to the cartridge, the needle cap is retained on the outer body when the control element is in the initial position, the needle cap is released from the outer body and the needle is covered by the outer body when the control element is in the first activating position, and the needle is exposed when the control element is in the second activating position.

AN INJECTION DEVICE

The present invention relates to an injection device. The injection device comprises a body () for holding a syringe that has a needle () at one end and a cap () that is removably attached to the body. The cap () has a needle shield to cover said needle. The injection device further comprises a gear assembly comprising a first rotary gear () and a first linear gear () to engage with the first rotary gear. The gear assembly is configured such that rotation of the first rotary gear drives the first linear gear to urge the needle shield away from the body. An actuator is provided that is configured to rotate the first rotary gear. 1. An injection device comprising:a body for holding a syringe that has a needle at one end;a cap that is removably attached to the body and has a needle shield to cover said needle;a gear assembly comprising a first rotary gear and a first linear gear to engage with the first rotary gear, configured such that rotation of the first rotary gear drives the first linear gear to urge the needle shield away from the body; and,an actuator configured to rotate the first rotary gear.2. An injection device according to claim 1 , wherein the first linear gear is fixed relative to the needle shield.3. An injection device according to claim 2 , wherein the first linear gear is formed in a peripheral surface of the needle shield.4. An injection device according to or claim 2 , wherein the cap further comprises an outer cap claim 2 , and wherein the needle shield is slidable relative to the outer cap such that the needle shield slides relative to the outer cap when the first rotary gear is rotated.5. An injection device according to any preceding claim claim 2 , wherein the first rotary gear is rotatably coupled to the body.6. An injection device according to any of to claim 2 , wherein the first rotary gear is rotatably coupled to the cap.7. An injection device according to any preceding claim claim 2 , wherein the actuator comprises a lever arm that has ...

INJECTION DEVICE

An injection device comprising: a housing arranged to contain a liquid medicament or a medicament cartridge; an electrical coil arranged around an inner surface or an outer surface of the housing; an electricity storage apparatus electrically connected to the electrical coil; and a magnet arranged to be movable axially within a defined space with respect to the electrical coil, such that electrical voltage is induced in the electrical coil and a current is generated to charge the electricity storage apparatus.

Drug Delivery Device

A drug delivery device for setting and dispensing a dose of a drug is presented having a support body having a first end defining a first opening and a second end defining a second opening and a centered outer indicator ring. A syringe barrel sealed by a stopper is slidably diposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, wherein the syringe barrel is positioned within the support body. A needle shield is adapted to be coupled to one fo the ends of the support body and slidably disposed thereon. An outer body is adapted to be coupled to the other end of the support body and slidably disposed thereon, wherein the outer indicator ring limits the movement of the outer body as well as of the needle shield. 115-. (canceled)16. A drug delivery device comprising:a support body having a first end defining a first opening and a second end defining a second opening, the support body configured to retain a syringe barrel sealed by a stopper slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly; anda needle shield configured to be coupled to the support body and slidably disposed thereon, the needle shield comprising a direction indicator.17. The device of claim 16 , wherein the needle shield comprises a mating surface to couple to the support body.18. The device of claim 16 , further comprising a detent mechanism configured to constrain movement of the needle shield relative to the support body by opposing the movement with a detent force.19. The device of claim 18 , wherein the detent mechanism comprises at least one guiding track defined on the support body and at least one retaining clip on the needle shield deflectable by the guiding track claim 18 , wherein the guiding track is configured such that the retaining clip follows a first path when the needle shield is depressed for needle extension and a different second path ...

Mounting arrangement and coupling assembly for a drug-delivery device

A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element. At least one of the plug element or the side wall of the recess are provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element and the housing part being mechanically coupled to each other.

Medication delivery device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device.

MICROWAVE FOAMING

The present invention relates to a process for foaming thermoplastic elastomers comprising a blowing agent, where the elastomer is heated by means of electromagnetic radiation to such an extent that the elastomer at least partly melts and foams to give a foam, wherein the frequency of the electromagnetic radiation is in the range from 0.01 GHz to 300 GHz. Further subject matter encompasses materials suitable for this process and the use thereof. 1. A process for foaming a thermoplastic elastomer comprising a blowing agent , the process comprising:heating the elastomer via electromagnetic radiation to such an extent that the elastomer at least partly melts and thus foams to give a foam,whereinthe electromagnetic radiation is applied at a frequency ranging from 0.01 GHz to 300 GHz, andthe elastomer is selected from the group consisting of a thermoplastic polyurethane (TPU), a thermoplastic polyester elastomer and a thermoplastic copolyamide.2. A process for foaming a thermoplastic elastomer comprising a blowing agent , the processing comprising:heating the elastomer via electromagnetic radiation so that the blowing agent expands the elastomer,whereinthe electromagnetic radiation is applied at a frequency ranging from 0.01 GHz to 300 GHz, andthe elastomer is selected from the group consisting of a thermoplastic polyurethane (TPU), a thermoplastic polyester elastomer and a thermoplastic copolyamide.3. The process according to claim 1 ,whereinthe elastomer absorbs electromagnetic radiation as a result of its chemical structure and/or the elastomer comprises at least one additive which absorbs the electromagnetic radiation, and the absorption contributes to heating the elastomer.4. The process according to claim 1 , whereinthe elastomer is a thermoplastic polyester elastomer selected from the group consisting of a polyether ester and a polyester ester and/orthe elastomer is a thermoplastic copolyamide selected from the group consisting of a polyetheramide and a ...

Isocyanate-epoxy-foam system

The present invention relates to a method for producing a rigid foam, which comprises reacting at least one polyisocyanate with a mixture comprising at least one polyepoxide, water, and at least one other hydrogen-acidic compound, the reaction taking place in the presence of a metal-free Lewis base having at least one nitrogen atom, to rigid foams obtainable by such a method, and to the use of a rigid foam of the invention for producing insulating materials, vacuum insulation panels, refrigeration equipment, construction elements, wind rotor blades, or elements for boatbuilding and vehicle construction.

Assembly for a drug delivery device and drug delivery device

An assembly for a drug delivery device is provided comprising a housing, a cartridge holder releasably connectable to the housing, a resilient member, and an interaction member which is configured to mechanically cooperate with the resilient member and with the cartridge holder. The resilient member is configured to rotationally bias the interaction member. The assembly has a locked state where the cartridge holder is connected to the housing, the cartridge holder being obstructed from movement with respect to the housing, and an unlocked state where the connection between the cartridge holder and the housing is released, the cartridge holder being freely moveable with respect to the housing.

AUTO-INJECTOR STORAGE DEVICE

A storage device for storing a plurality of auto-injectors, the device configured to activate an auto-injector upon removal of the auto-injector from the device. 1. A storage device for storing a plurality of auto-injectors , the device configured to activate an auto-injector upon removal of the auto-injector from the device.2. The device of claim 1 , wherein the device is configured to activate the auto-injector by at least partially opening a blister pack containing the auto-injector.3. The device of or claim 1 , wherein the device is configured to activate the auto-injector by modifying the auto-injector.4. The device of claim 3 , wherein the device is configured to activate the auto-injector by breaking or completing an electrical circuit of the auto-injector.5. The device of or claim 3 , wherein the device is configured to activate the auto-injector by detaching a part of the auto-injector.6. The device of any preceding claim comprising a connector coupled to the auto-injector and a surface of the device claim 3 , wherein the connector is configured to decouple from the auto-injector to activate the auto-injector.7. The device of claim 6 , wherein the device comprises a blister pack configured to contain the auto-injector claim 6 , wherein the connector is coupled to the blister pack and the auto-injector and is configured to decouple from the auto-injector to activate the auto-injector.8. The device of any preceding claim claim 6 , wherein the device comprises a box configured to contain the auto-injector claim 6 , wherein the device comprises a dispenser arranged to dispense an auto-injector contained within the box claim 6 , and wherein the dispenser is configured to inhibit removal of two or more auto-injectors from the device simultaneously.9. The device of claim 8 , wherein the dispenser comprises a drawer moveable between an open position and a closed position claim 8 , wherein an auto-injector can be removed from the device via the drawer when in the ...

Injection device with slidable member for removing a cap with a needle shield

The present disclosure relates to an injection device. The injection device comprises a cap and a body for holding a syringe that has a needle at one end. The cap is removably attached to the body and has a needle shield to receive the needle. The injection device further comprises an actuator that is slidable relative to the body in the longitudinal direction of the body to urge the needle shield away from the body.

Personal care appliance housing

An electric toothbrush handle is disclosed that includes a housing with a first part and a second part, and an electric motor contained within the housing and operably connected to a shaft extending from the housing for driving a brush. The second housing part is removably connectable to the first housing part by a manually releasable latch that opens to disconnect the second housing part from the first housing part in response to squeezing the first housing part adjacent the latch.

MEDICAL DEVICE

The medical device comprises a wave spring or wave washer in a mechanism to engage or disengage a first element and a second element. The invention also discloses the use of a multiple wave spring or wave washer comprising at least two waved spring layers in a medical device. 1. A medical device comprising:a mechanism;a first element and a second element of the mechanism;a coupling device engaging the first element and the second element;a spring arranged in contact with at least one of the first element and the second element and tending to engage or disengage the first element and the second element; andthe spring being a wave spring or wave washer.2. The medical device according to claim 1 , wherein the spring is formed by a helically curved wire comprising waves in the direction in which the spring force is to be exerted.3. The medical device according to claim 1 , wherein the spring is formed of at least two waved layers of an elastic material mounted one above the other.4. The medical device according to claim 1 , wherein the first element and the second element of the mechanism are nuts and the coupling device is a gear formed by surface structures of the nuts.5. The medical device according to claim 1 , wherein the device is a pen-type drug delivery device or injection device.6. The medical device according to claim 1 , further comprising:a body;a receptacle in the body;a piston movable in the receptacle by means of a piston rod having an axis;the piston rod going through holes in the first element and the second element of the mechanism;the first element being engaged with the body in such a manner as to inhibit a rotation of the first element relatively to the body around the axis of the piston rod;the second element being engaged with the piston rod in such a manner as to generate an axial rotation of the piston rod relatively to the second element when the piston rod is moved along its axis relatively to the second element;the coupling device engaging ...

SYSTEM FOR CAP REMOVAL

The present invention relates to an auto-injector device () for delivering a liquid medicament, the auto injector comprising an injector body, a syringe () received in the injector body, a needle () disposed in a first end of syringe to extend toward an opening of the injector body, a needle shield () removeably attached to the syringe to enclose the needle and an injector cap removeably received in the opening of the injector body to enclose the needle shield. The injector cap () comprises at least one engaging element to engage with the needle shield and the needle shield comprises a rupture portion. The at least one engaging element is configured to rupture the rupture portion as the cap is removed from the body. The at least one engaging element is configured to engage with at least a portion of the needle shield to retain at least a portion of the needle shield in the cap when the cap is removed from the body. 1. An auto-injector device for delivering a liquid medicament , comprising:an injector body,a syringe received in the injector body,a needle disposed in a first end of syringe to extend toward an opening of the injector body,a needle shield removeably attached to the syringe to enclose the needle, andan injector cap removeably received in the opening of the injector body to enclose the needle shield, wherein the injector cap comprises at least one engaging element to engage with the needle shield, and wherein the needle shield comprises a rupture portion, the at least one engaging element being configured to rupture the rupture portion as the cap is removed from the body, the at least one engaging element configured to engage with at least a portion of the needle shield to retain at least a portion of the needle shield in the cap when the cap is removed from the body.2. An auto injector device according to claim 1 , wherein the rupture portion comprises a line of weakening.3. An auto injector device according to claim 2 , wherein the line of weakening is ...

CAP FOR AN INJECTION DEVICE

The present disclosure relates to a cap for an injection device. The injection device comprises a body for holding a syringe having a needle extending from an end thereof. The cap is removably attachable to the body. The cap comprises an actuator and a needle shield to cover said needle. The cap further comprises a coupling between the actuator and the needle shield. The coupling is configured such that when the cap is attached to the body of an injection device axial movement of the actuator away from the body causes rotation of the needle shield relative to the body.

DRUG DELIVERY DEVICE WITH PROTECTIVE NEEDLE CAP CONTROL AND DEVICE ACTIVATION MECHANISM

A drug delivery device includes an outer body receiving a cartridge with a needle, a needle cap adapted to be coupled to the outer body and to cover the needle and a control mechanism for activating the drug delivery device. The control mechanism includes a control element received within the outer body and axially and/or rotationally movable relative to the outer body between an initial position, a first activating position, and a second activating position. The control element is coupled to the needle cap and to the cartridge, the needle cap is retained on the outer body when the control element is in the initial position, the needle cap is released from the outer body and the needle is covered by the outer body when the control element is in the first activating position, and the needle is exposed when the control element is in the second activating position. 115-. (canceled)16. A drug delivery device comprising:an outer body adapted to receive a cartridge with a needle;a needle cap assembly adapted to be coupled to the outer body and to cover the needle; anda control mechanism for activating the drug delivery device, the control mechanism comprises a control element that is received within the outer body and movable relative to the outer body between an initial position, a first activating position, and a second activating position,wherein the control element is configured to be coupled to the needle cap assembly and to the cartridge,wherein the needle cap assembly is retained on the outer body when the control element is in the initial position,wherein the needle cap assembly is released from the outer body and the needle is covered by the outer body when the control element is in the first activating position, andwherein the needle is exposed when the control element is in the second activating position.17. The drug delivery device according to claim 16 , wherein the control element comprises an activating element operable from an outside of the outer body and ...

Medication delivery device

A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge.

ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE

An assembly for a drug delivery device is provided comprising a housing, a cartridge holder releasably connectable to the housing, a resilient member, and an interaction member which is configured to mechanically cooperate with the resilient member and with the cartridge holder. The resilient member is configured to rotationally bias the interaction member. The assembly has a locked state where the cartridge holder is connected to the housing, the cartridge holder being obstructed from movement with respect to the housing, and an unlocked state where the connection between the cartridge holder and the housing is released, the cartridge holder being freely moveable with respect to the housing. 119-. (canceled)20. An assembly for a drug delivery device comprisinga housing,a cartridge holder releasably connectable to the housing,a resilient member,an interaction member which is configured to mechanically cooperate with the resilient member and with the cartridge holder,wherein the resilient member or an additional resilient member is configured to rotationally bias the interaction member, wherein the assembly has a locked state where the cartridge holder is connected to the housing, the cartridge holder being obstructed from movement with respect to the housing, and an unlocked state where the connection between the cartridge holder and the housing is released, the cartridge holder being freely moveable with respect to the housing,and wherein, for switching from the unlocked state into the locked state, the cartridge holder is brought into mechanical cooperation with the interaction member, the cartridge holder is rotated in a first direction with respect to the housing, the interaction member thereby being rotated in the first direction such that the interaction member mechanically cooperates with the resilient member and such that a rotational force exerted on the interaction member by means of the resilient member is overcome for switching the assembly from the ...

Coarse-cell polyurethane elastomers

The present invention relates to an open-cell polyurethane foam comprising polyester and polyether structures and having a density of 70 to 300 g/L, 1 to 20 cells/cm, a rebound intensity greater than 30%, an elongation at break of greater than 200%, a tear propagation resistance of greater than 1.2 N/mm and a tensile strength of greater than 200 kPa. The present invention further relates to a process for producing inventive open-cell polyurethane sponges and to the use thereof as a pipe cleaning sponge.

DRUG DELIVERY DEVICE BODY

The body of a portable drug delivery device, especially an injection pen, is provided on its outer surface with a recess, in which directly accessible information is displayed. The information is protected against damages during everyday use by the recessed location. 1. A drug delivery device body , comprising:an outer surface anda recess in the outer surface, the recess being provided for the display of a piece of information, whereinthe recess is provided with a structure in relief.2. The drug delivery device body according to claim 1 , wherein the structure in relief does not exceed the level of the outer surface of the body as present outside the recess.3. The drug delivery device body according to claim 1 , wherein the structure in relief forms an integral part of the body.4. The drug delivery device body according to claim 1 , further comprising:a label located within the recess.5. The drug delivery device body according to claim 4 , wherein the label does not exceed the level of the outer surface of the body as present outside the recess.6. The drug delivery device body according to claim 1 , further comprising:a transparent cover covering the recess and not exceeding the level of the outer surface of the body as present outside the recess.7. The drug delivery device body according to claim 1 , further comprising:a mechanism, which is provided for the operation of the device, the mechanism being located in an inner volume of the body on a side of the body that is opposite to the outer surface.8. The drug delivery device body according to claim 7 , further comprising:an operation button, which is provided for the operation of the device, andthe recess being located in the vicinity of the operation button.9. The drug delivery device body according to claim 1 , further comprising:the body forming part of a pen-type drug delivery device or injection pen.10. The drug delivery device body according to claim 1 , wherein the information is about a drug to be ...

Techniques for automatically generating tests for programmable circuits

Programmable circuits have a programmable interconnect structure that connects programmable circuit elements. Tests patterns can be automatically generated for the programmable circuit elements and interconnections on a programmable circuit. A connectivity graph represents programmable interconnections and functions as nodes. Tests routes are generated that connect the nodes in the connectivity graph between control points and observation points on the programmable circuit. The routes are grouped into configuration patterns that can be tested in one test cycle. Test vectors are then applied to the routes to determine if the interconnects and circuit functions are operable. Systems and methods of the present invention automatically create test patterns for a programmable circuit to reduce engineer time. The present invention also reduces test time and resources by increasing the number of interconnections and circuit elements tested in each configuration pattern.

AN INJECTION DEVICE WITH PROTECTIVE CAP ALLOWING ELECTROMAGNETIC FIELD INDUCTION

An injection device comprising: a housing arranged to contain a liquid medicament or a medicament cartridge; an electrical coil arranged at the housing; a removable cap arranged to be removably engaged with an end of the housing; and a magnet arranged within the removable cap; wherein when the removable cap is disengaged from the housing, the magnet moves with respect to the electrical coil such that electrical voltage is induced in the electrical coil and a current is generated.

System and method for supporting on the use of an injection device

A system for supporting on the use of an injection device includes a display and a processor configured to determine the injection device, to obtain data on use of the determined injection device and to add at least one overlay on the display, wherein the at least one overlay is generated depending on the obtained data on use of the determined injection device. The processor is configured to adapt the at least one overlay depending on a context of application of the injection device, the context of application of the injection device including at least one of the following: ambient light; time; date; temperature; use history of the injection device; drug; injection site; dosage.

DRUG DELIVERY DEVICE

The present disclosure relates to a drug delivery device, including: a body adapted to retain a medicament cartridge, a cap attachable to a distal end of the body to cover an opening thereof, an activation mechanism arranged within the body, wherein the cap includes an activation feature adapted to be inserted into an activation opening of the body in order to actuate the activation mechanism or allow actuation thereof.

Method for Manufacturing a Composite Work Piece for a Drug Delivery Device and Composite Work Piece for a Drug Delivery Device

Method for manufacturing a composite work piece for a drug delivery device, comprising the steps: Providing a first work piece part 1 and a second work piece part 2, arranging both work piece parts 1, 2 with respect to each other in such a way that both work piece parts 1, 2 are in mechanical contact with one another in a contact area 3, irradiating a surface of the first work piece part 1 with electromagnetic radiation, thereby softening the first work piece part 1 and/or the second work piece part 2 in a region adjacent to the contact area 3, and joining the first work piece part 1 to the second work piece part 2 in the contact area 3 for the composite work piece. Furthermore, a composite work piece for a drug delivery device is provided.

Anisotropic cellular elastomers

The invention relates to a cellular elastomer which is anisotropic, with anisotropy being defined by the compressive modulus in one of three orthogonal directions being greater than that in the other two directions by a factor of at least 1.5. The invention also relates to a cellular elastomer containing magnetizable particles which have a chain-like alignment along one spatial direction. The invention also relates to a process for producing a cellular elastomer containing magnetiable particles and the use of such elastomers in articles of manufacture.

Stents Formed From Dissimilar Metals for Tissue Growth Control

Stents formed from dissimilar materials configured to control tissue growth. A stent may be formed from a composite wire helically wound into a stent having a tubular configuration. The composite wire includes a first wire and a second wire coupled together, the first and second wires being formed from dissimilar metals such that a potential difference is formed when the dissimilar metals are exposed to bodily fluids. The potential difference is configured to inhibit cell proliferation and thereby control tissue growth around the stent after implantation. A stent may be formed from a hollow composite wire including an inner member that includes first and second longitudinal strips formed from dissimilar metals. A stent may be formed from a composite wire having a plurality of windows along a length of the composite wire. An insert formed from a dissimilar metal is disposed within each window of the plurality of windows. 1. A stent configured to control tissue growth , the stent comprising:a composite wire helically wound into a stent having a tubular configuration, wherein the composite wire includes a first wire and a second wire coupled together, the first and second wires being formed from dissimilar metals such that a potential difference is formed when the dissimilar metals are exposed to bodily fluids, wherein the potential difference is configured to inhibit cell proliferation and thereby control tissue growth around the stent after implantation.2. The stent of claim 1 , wherein the first wire is shaped into a first waveform and the second wire is shaped into a second waveform claim 1 , the second waveform being configured to nest within the first waveform when the first and second wires are coupled together.3. The stent of claim 2 , wherein the first waveform includes a plurality of bends and the second waveform includes a plurality of bends claim 2 , and at least some of the bends of the first waveform are fused to at least some of the bends of the second ...

INJECTION DEVICE WITH NEEDLE SHIELD REMOVAL MECHANISM

The present disclosure relates to an injection device. The injection device comprises a body for holding a syringe that has a needle at one end and a cap that is removably attached to the body. The cap has a needle shield to cover said needle. The injection device further comprises an actuator member and a translating member. The actuator member is pivotally coupled to one of the cap or body. The translating member is connected to the actuator member and is configured such that pivotal movement of the actuator member relative to said one of the cap or body causes movement of the translating member relative to the body to urge the needle shield away from the body. 116-. (canceled)17. An injection device comprising:a body configured to hold a syringe, the syringe having a needle at one end;a cap comprising a needle shield configured to cover the needle, wherein the cap is configured to be removably attached to the body;an actuator member pivotally coupled to one of the cap or the body; anda translating member connected to the actuator member and configured such that pivotal movement of the actuator member relative to the one of the cap or the body causes movement of the translating member relative to the body to urge the needle shield away from the body.18. The injection device according to claim 17 , wherein the actuator member is pivotable from an initial position to an actuated position claim 17 , wherein in the initial position claim 17 , a portion of the actuator member is spaced from a central axis of the injector device claim 17 , and in the actuated position claim 17 , the portion of the actuator member is moved towards the central axis.19. The injection device according to claim 18 , wherein when the actuator member is in the initial position the actuator member extends at an acute angle to the central axis and the needle shield covers the needle claim 18 , and when the actuator member is in the actuated position the acute angle between the actuator member ...

Assembly for a drug delivery device and drug delivery device

An assembly includes a cartridge containing doses of a drug and a piston rod adapted and arranged to expel drug from the cartridge, the piston rod including a thread. The assembly further includes a nut member adapted and arranged to be rotated with respect to the piston rod about a rotational axis. The assembly further comprises a last dose stop mechanism adapted including at least one first interaction member and at least one second interaction member provided by the piston rod and at least one first stop member and at least one second stop member provided by the nut member. The interaction members and the stop members are configured to mechanically cooperate with one another such that further relative movement of the nut member and the piston rod for setting a dose of the drug is prevented.

METHOD AND ARRANGEMENT FOR CHANGING THE SHAPE OF A SHEET-LIKE WORKPIECE

A method for changing the shape of a sheet-like workpiece, which has a mould recess formed by reducing the thickness of the material, includes arranging the workpiece on at least two spaced-apart supporting elements of a machine bed, and forming the workpiece into a final shape by step-by-step free bending. The steps of bending a part of the workpiece by lowering an upper die between the supporting elements from a waiting position into a forming position, raising the upper die into the waiting position and moving the position of the workpiece relative to the machine bed in at least one infeed direction are performed repetitively. Before the workpiece is formed into the final shape, a filling element, which is adapted to the mould recess and designed to make up the material thickness, is produced and is arranged in the region of the mould recess. An arrangement is also provided. 1. A method for changing the shape of a sheet-like workpiece , which has a mould recess formed by reducing the thickness of the material , comprising:arranging the workpiece on at least two spaced-apart supporting elements of a machine bed;{'claim-text': ['bending a part of the workpiece by lowering an upper die between the supporting elements from a waiting position into a forming position;', 'raising the upper die into the waiting position; and', 'moving the position of the workpiece relative to the machine bed in at least one infeed direction;'], '#text': 'forming the workpiece into a final shape by step-by-step free bending, in that the steps of;'}are performed repetitively;wherein before the workpiece is formed into the final shape, a filling element, which is adapted to the mould recess and designed to make up the material thickness, is produced and is arranged in the region of the mould recess.2. The method according to claim 1 , wherein the filling element is produced at least substantially as a negative form of the mould recess.3. The method according to claim 1 , wherein claim 1 , ...

Medical Device Having a Mechanism and Use of a Low-Friction Synthetic Material Within a Medical Device

A first movable element ( 4 ) and a second movable element ( 7 ) of a mechanism in a medical device are arranged in such a manner that, during an operation of the mechanism, a surface of the first element slides on a surface of the second element. The first element and the second element are formed from materials providing a coefficient of sliding friction of said surfaces on one another of less than 0.14 at a relative velocity of 2 mm per second.

Weight selection with alignment indicia

A weightlifting apparatus has at least one indicia on at least one weight plate indicating the amount of weight of the weight plate. The barbell of the weightlifting apparatus can have alignment indicia on an outer surface thereon. The weightlifting apparatus is configured to selectively display the amount of weight on the weightlifting apparatus. The alignment indicia of the barbell is aligned with the at least one indicia on the weight plate to mark or indicate which indicia of a plurality of indicia is the selected indicia to be viewed.

Method and apparatus for application specific test of PLDs

Method and apparatus for application specific testing of PLDs. The PLD has a number of resources, less than all of which are used for implementing a customer application. The method includes the following steps. The set of resources that is used for implementing the customer application is identified. A test is then performed only on the set and a test result is generated. Defective resources may be replaced. The PLD is identified as defective only if one of the resources associated with the customer application is defective. Such application specific testing allows the ability of the customer to perform in-system testing, the reduction of the time required for testing the PLD, and the testing of PLDs based on knowledge of the customer's application, among other advantages.

AN INJECTION DEVICE

The present disclosure relates to an injection device. The injection device comprises a body for holding a syringe having a needle extending from one end thereof and a cap that is removably attached to the body. The cap has a needle shield to cover said needle. The injection device further comprises a biasing member and a lock. The biasing member is configured to urge at least a part of the cap away from the body. The lock is moveable between a locked state, wherein the lock holds the cap and body together, and an unlocked state, wherein the cap and body are able to move apart. 1. An injection device comprising:a body for holding a syringe having a needle at one end thereof;a cap that is removably attached to the body and has an outer cap and a needle shield configured to frictionally engage with said syringe to cover said needle;a biasing member that is configured to urge at least a part of the cap away from the body; and,a lock that is moveable between a locked state, wherein the lock holds the cap and body together, and an unlocked state, wherein the cap and body are able to move apart,wherein the outer cap is rotatable relative to the body to move the lock to the unlocked state.2. An injection device according to claim 1 , wherein the biasing member is configured to urge the entire cap away from the body when the lock is in the locked state.3. An injection device according to claim 1 , wherein the biasing member is a helical spring.4. An injection device according to claim 1 , wherein the lock comprises a latch or bayonet connection.5. An injection device according to claim 1 , wherein the cap is moveable relative to the body to move the lock from the locked state to the unlocked state.6. An injection device according to claim 1 , wherein the cap is moveable relative to the body in a first direction to move the lock from the locked state to an intermediate state claim 1 , and wherein the cap is moveable relative to the body in a second direction that is ...

DRUG DELIVERY DEVICE

A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated. 1. A drug delivery device , comprising:a body having a receptacle for a drug;a piston rod in the body, the piston rod being movable relatively to the body and being provided for expelling the drug out of the receptacle;a mechanism provided to drive the piston rod while delivering the drug, the piston rod having a start position with respect to the mechanism;a device for guiding the movement of the piston rod relatively to the body while delivering the drug; anda device for releasing the piston rod from the device for guiding the movement, the device for releasing being provided to enable a reset of the piston rod to the start position; and{'b': '8', 'wherein the reset of the piston rod is generated by the weight of the piston rod (), which resets the piston rod by gravitational force or wherein the reset of the piston rod is generated by a spring element.'}2. The drug delivery device according to claim 1 , further comprising:the device for guiding the movement of the piston rod comprising a piston rod nut;a device for fixing the piston rod nut relatively to the body;the device for releasing the piston rod comprising a spring provided for releasing the piston rod nut from being fixed relatively to the body; andthe piston rod having a weight, which resets the piston rod by a gravitational force when the piston rod nut is released and the drug delivery device is directed in such a manner as to make the gravitational force drive the piston rod towards the start position.3. The drug delivery ...

Stents formed from dissimilar metals for tissue growth control

Stents formed from dissimilar materials configured to control tissue growth. A stent may be formed from a composite wire helically wound into a stent having a tubular configuration. The composite wire includes a first wire and a second wire coupled together, the first and second wires being formed from dissimilar metals such that a potential difference is formed when the dissimilar metals are exposed to bodily fluids. The potential difference is configured to inhibit cell proliferation and thereby control tissue growth around the stent after implantation. A stent may be formed from a hollow composite wire including an inner member that includes first and second longitudinal strips formed from dissimilar metals. A stent may be formed from a composite wire having a plurality of windows along a length of the composite wire. An insert formed from a dissimilar metal is disposed within each window of the plurality of windows.

MOUNTING ARRANGEMENT AND COUPLING ASSEMBLY FOR A DRUG-DELIVERY DEVICE

A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element. At least one of the plug element or the side wall of the recess are provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element and the housing part being mechanically coupled to each other.

Supporting wing structure for an aircraft, and aircraft having such a supporting wing structure

A supporting wing structure for an aircraft, in particular for a load-carrying and/or passenger-carrying aircraft, preferably an aircraft in the form of a vertical take-off and landing multicopter having a plurality of electrically driven rotors which are disposed in a distributed manner. The supporting wing structure has a plurality of struts. A first number of the struts are at least largely disposed in a first direction, while a second number of the struts are at least largely disposed in a second direction, the second direction being oriented orthogonal to the first direction. At least the struts of the second number have an aerodynamic profile in cross section, and/or in the struts are connected to one another at least in pairs between neighboring struts by a connecting structure, preferably from individual connecting segments, and the connecting structure or the connecting segments have an aerodynamic profiling. Furthermore an aircraft is provided equipped with such a supporting wing ...

Testing hard-wired IP interface signals using a soft scan chain

A set of boundary scan registers are implemented by reconfiguring the functional blocks of a reconfigurable device. This "soft-wired" set of boundary scan registers can be used to test the interface connections between the IP core and the functional blocks of the reconfigurable device. Additionally, the set of boundary scan registers only exists when a testing configuration is loaded into the reconfigurable device. When testing is complete, the testing configuration is erased and the functional blocks may implement other operations. Thus, the set of boundary scan registers consumes no additional chip area. Furthermore, as the set of boundary scan registers disappears after testing, a functional path enabling normal operation modes is unnecessary. Therefore, manually created functional test data is not needed. Instead, ATPG software can create test data from hardware descriptions of the IP core and the set of boundary scan registers.

Medical device

The medical device comprises a wave spring or wave washer in a mechanism to engage or disengage a first element and a second element. The invention also discloses the use of a multiple wave spring or wave washer comprising at least two waved spring layers in a medical device.

Dose button for a drug delivery device and method for manufacturing a dose button

The present invention relates to a drug delivery device (6) comprising a dose button (1). Furthermore it relates to a method for manufacturing a dose button (1) by using a cutting-off process. The aim of the present invention is to minimize the risk of using a drug delivery device (6) containing a wrong drug. By means of tactile features, a drug delivery device (6) is distinguishable from another drug delivery device (6) containing another type of drug. This tactile feature is manufactured by using a dose button (1) out of metal which is milled or lathed.

Sample processing devices

Methods and devices for thermal processing of multiple samples at the same time are disclosed. The sample processing devices provide process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas.

Dry shaving apparatus

Dry shaving apparatus comprises a drive source provided in a housing; a first shaving unit (111) having a first outer cutter and a first undercutter coupled to the drive source and mounted for movement beneath said first outer cutter, and a second shaving unit (112, 113), having a second outer cutter and a second undercutter coupled to the drive source and mounted for oscillatory movement beneath said second outer cutter. The first outer cutter is coupled to the drive source and is mounted for oscillatory movement to serve as a skin agitation member; and the first outer cutter and the second undercutter are arranged to be driven at the same frequency by the drive source.

SYSTEM AND METHOD FOR SUPPORTING ON THE USE OF AN INJECTION DEVICE

A system for supporting on the use of an injection device comprises a display and a processor configured to determine the injection device, to obtain data on use of the determined injection device and to add at least one overlay on the display, wherein the at least one overlay is generated depending on the obtained data on use of the determined injection device. The processor is configured to adapt the at least one overlay depending on a context of application of the injection device, the context of application of the injection device comprising at least one of the following: ambient light; time; date; temperature; use history of the injection device; drug; injection site; dosage. 1. A system for supporting on the use of an injection device comprising a display and a processor being configured to determine the injection device , to obtain data on use of the determined injection device and to add at least one overlay on the display , wherein the at least one overlay is generated depending on the obtained data on use of the determined injection device , and wherein the processor is configured to adapt the at least one overlay depending on a context of application of the injection device , the context of application of the injection device comprising at least one of the following: ambient light; time; date; temperature; use history of the injection device; drug; injection site; dosage.2. A system of claim 1 , wherein the at least one overlay comprises textual information claim 1 , a video and/or one or more images.3. A system of or claim 1 , wherein the processor is configured to determine the injection device with image processing of a captured image of the injection device claim 1 , wherein the image processing comprises detecting a form of claim 1 , a colour of claim 1 , a code claim 1 , a tag and/or a label on the injector device claim 1 , and determining the injection device depending on of the detected form claim 1 , colour claim 1 , code claim 1 , tag claim 1 , ...

Toothbrush

An electric toothbrush having a handpiece, a bristle holder which is arranged on a head portion of the handpiece and is rotatable about an axis of rotation of the bristle holder, and a drive mechanism for the bristle holder. The drive mechanism includes a motor which is arranged on the handpiece, and a transmission member which transfers a driving motion from the motor to the bristle holder. The transmission member is arranged to rock in multiple axes and is arranged to be driven by the motor such that is approximately traverses a double conical path.

Dry shaving apparatus

The invention is directed to a dry shaving apparatus with a housing, comprising a housing part (G), at least one cutter element capable of reciprocating in a horizontal plane (E) and a removable frame (WR) having at least one cutter element (S) and detachably held on the housing part (G) by at least two detent mechanisms (R1, R2; R3, R4), said detent mechanisms (R1, R2; R3, R4) being formed by a seating surface (20, 21) provided on the removable frame (WR) and a seating surface (80, 90) of a resiliently mounted detent element (18, 19) exerting a locking force (FR), wherein the detent mechanisms (R1, R2; R3, R4) are capable of exerting a holding function and a vibration-free positioning function of the removable frame (WR) on the housing part (G).

DRUG DELIVERY DEVICE AND CARTRIDGE HOLDER FOR A DRUG DELIVERY DEVICE

A drug delivery device is provided with a cartridge holder having at least one guide track, and a body having at least one interaction member adapted and arranged to mechanically cooperate with the at least one guide track. The guide track has a first section and a second section, wherein the path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the path defined by the first section with the longitudinal axis is smaller than the angle which is enclosed by the path defined by the second section with the longitudinal axis.

Toothbrush

An electric toothbrush having a handpiece, a bristle holder which is arranged on a head portion of the handpiece and is rotatable about an axis of rotation of the bristle holder, and a drive mechanism for the bristle holder. The drive mechanism includes a motor which is arranged on the handpiece, and a transmission member which transfers a driving motion from the motor to the bristle holder. A drive rocker is provided as transmission member, and is arranged to rock in multiple axes and is driven by the motor such that it approximately traverses a double conical path.

CAP AND CAP REMOVAL DEVICE

A cap removal device for removing and retaining a plurality of caps from a drug delivery device includes a body having a plurality of recesses. Each of the plurality of recesses comprises a shape corresponding to a shape of one of the plurality of caps and each recess is provided with an engagement member adapted to engage a cap. Furthermore, a cap adapted to be mounted to a distal end of a drug delivery device includes a distal portion comprising a shape corresponding to a shape of a recess of the cap removal device.

Auto-injector

An auto-injector for delivering a liquid medicament comprising: a housing arranged to contain a syringe and a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end intended to be applied against an injection site, wherein the syringe comprises: a plurality of plunger elements arranged along a length of the syringe between the proximal end of the housing and the piston, each of the plurality of plunger elements having a longitudinal axis; and a cord arranged to connect the plurality of plunger elements, wherein the plunger elements are configured to become aligned along their axes to push the piston towards the distal end to displace the medicament when the cord is acted on by a driving force.

Electric razor

The invention is directed to a dry shaving apparatus with a housing in which an electric drive mechanism is provided having a drive element for the transmission of a driving motion to at least one cutting element reciprocating in directions of movement, and with at least one movably mounted shaving head formed by a shaving head frame in which at least two cooperating cutting elements are provided, wherein the electric drive mechanism is mounted for oscillation in the housing and the shaving head is adapted to be set in oscillation by the oscillatory motions of the electric drive mechanism.

SYSTEM FOR CAP REMOVAL

The present disclosure relates to an auto-injector for delivering a liquid medicament, the auto-injector comprises an injector body, a syringe received in the injector body, a needle disposed in a first end of the syringe to extend toward an opening of the injector body, an injector cap to enclose the opening and cover the needle and a releasable attachment mechanism configured to secure the cap in place covering the needle. The releasable attachment mechanism comprises first and second engaging parts, wherein the first and second engaging parts cooperate in an attached position to secure the cap in position covering the needle, and wherein the attachment mechanism is configured to move into a release position in which the first and second engaging parts are in reduced cooperation when above a threshold temperature to facilitate detachment of the injector cap to expose the needle.

Producing rigid polymer foams

A process for producing a rigid polymer foam comprises reacting components A to C in the presence of component D or an isocyanate-functional prepolymer of components A and B with component C in the presence of component D, the total amount of which is 100 wt %, (A) 35 to 65 wt % of at least one polyisocyanate component A, (B) 5 to 50 wt % of at least one polyol component B, (C) 1 to 59 wt % of at least one polycarboxylic acid component C, and (D) 0.01 to 3 wt % of at least one Lewis base component D, wherein the reaction takes place with release of carbon dioxide.

Sample processing devices and carriers

Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas. The carriers may be used to apply selective compression to the sample processing devices.

AN INJECTION DEVICE WITH AN EXPANDABLE CAVITY

An injector device comprises a housing having a distal end and a proximal end; a medicament reservoir; a stopper for expelling a medicament out of the medicament reservoir; a cavity having an expandable volume which is arranged to move the reservoir or the stopper in a distal direction when the cavity is at least partially inflated with a fluid; and a fluid reservoir which is configured to dispense the fluid in to the cavity; wherein the cavity comprises a flexible tube, and the fluid reservoir is configured to dispense the fluid into the flexible tube. 1. An injector device comprising:a housing having a distal end and a proximal end;a medicament reservoir;a stopper for expelling a medicament out of the medicament reservoir;a cavity having an expandable volume which is arranged to move the reservoir or the stopper in a distal direction when the cavity is at least partially inflated with a fluid; anda fluid reservoir which is configured to dispense the fluid in to the cavity;wherein the cavity comprises a flexible tube, and the fluid reservoir is configured to dispense the fluid into the flexible tube.2. The injector device of claim 1 , wherein a longitudinal extent of the flexible tube when inflated is greater than a longitudinal extent of the fluid reservoir.3. The injector device of claim 1 , wherein a volume of the fluid reservoir is greater than a volume of the flexible tube when inflated.4. The injector device of claim 1 , further comprising a piston for expelling the fluid from the fluid reservoir into the cavity.5. The injector device of claim 1 , wherein the fluid reservoir comprises:a first chamber for storing a first medium; anda second chamber for storing a second medium;wherein the first medium and second medium react if mixed to form a third medium having a greater volume than the total volume of the first and second mediums, andwherein the third medium is expelled into the cavity by fluid pressure resulting from mixing the first medium and the second ...

Dry shaving apparatus

Dry shaving apparatus comprises a drive source provided in a housing; a first shaving unit (111) having a first outer cutter and a first undercutter coupled to the drive source and mounted for movement beneath said first outer cutter, and a second shaving unit (112, 113), having a second outer cutter and a second undercutter coupled to the drive source and mounted for oscillatory movement beneath said second outer cutter. The first outer cutter is coupled to the drive source and is mounted for oscillatory movement to serve as a skin agitation member; and the first outer cutter and the second undercutter are arranged to be driven at the same frequency by the drive source.

Method for producing particle foams based on thermoplastic elastomers, by thermal bonding using microwaves

A method for producing bead foams from foam beads based on thermoplastic elastomers, especially thermoplastic polyurethane, comprises foam beads being wetted with a polar liquid and joined together thermally in a mold via high-frequency electromagnetic radiation, especially microwave radiation, and also the bead foams obtainable therefrom.

MOUNTING ARRANGEMENT AND COUPLING ASSEMBLY FOR A DRUG-DELIVERY DEVICE

A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element. At least one of the plug element or the side wall of the recess are provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element and the housing part being mechanically coupled to each other. 1. A mounting arrangement for a drug-delivery device comprisinga plug element with a longitudinal axis (L) and a housing part having a recess with a side wall which is adapted to receive the plug element,at least one of the plug element or the side wall of the recess being provided with a protrusion for fixing the plug element in a given position relative to the housing part by a force-fit engagement, wherein the longitudinal profile of the protrusion is inclined along a longitudinal end section of the protrusion for the purpose of facilitating the insertion of the plug element into the recess when establishing the force-fit engagement.2. The mounting arrangement according to claim 1 , wherein the longitudinal profile of the protrusion is inclined along the longitudinal end section such that the inclination is monotonous.3. The mounting arrangement according to claim 2 , wherein the inclination of the longitudinal profile is constant.41. The mounting arrangement according to claim 1 , wherein the longitudinal profile of the protrusion is arranged and designed such that the longitudinal angle (A) between the longitudinal end section and the longitudinal axis (L) is between 1° and 30°.5. The mounting arrangement according to claim 1 , wherein the longitudinal profile of the protrusion is designed such that it comprises the shape of a convex curve.6. The mounting arrangement ...

User Scriptable Server Initiated User Interface Creation

A computer-implemented method of providing user interfaces in association with network hosted computer scripts is disclosed. A group of selectable user interface elements is provided to a macro author. The elements include behavior that, when controls generated by the elements are selected by a computing device user, cause a web-connected server separate from the computing device to perform one or more operations. A selection by the macro author of a user interface element and an identification of one or more parameters for the element is received. Macro code to generate controls associated with the author-selected elements to be associated with a first macro is executed, the first macro stored to be called from and execute on computing devices different from the device used by the macro author. The macro code is stored and the generated macro code is provided for access by users of a hosted computer system. 1. A computer-implemented method of managing computer macros , comprising:providing to a macro author, with a computer system, a group of selectable user interface elements, the elements including behavior that, when controls generated by the elements are selected by a user of a computing device, cause a web-connected server that is separate from the computing device to perform one or more defined operations;receiving a selection by the macro author of one of the selectable user interface elements, and an identification of one or more parameters for the author-selected element;causing, by the computer system, macro code to cause generation of controls associated with the author-selected elements to be associated with a first macro, the first macro stored to be called from and execute on computing devices other than a device used by the macro author; andstoring the macro code and making the generated macro code available for access by users of a hosted computer system other than the macro author.2. The method of claim 1 , further comprising associating the first ...

Dose Button for a Drug Delivery Device and Method for Manufacturing a Dose Button

The present invention relates to a drug delivery device () comprising a dose button (). Furthermore it relates to a method for manufacturing a dose button () by using a cutting-off process. The aim of the present invention is to minimize the risk of using a drug delivery device () containing a wrong drug. By means of tactile features, a drug delivery device () is distinguishable from another drug delivery device () containing another type of drug. This tactile feature is manufactured by using a dose button () out of metal which is milled or lathed. 1. Dose button for a drug delivery device , manufactured by means of a cutting-off process.2. Dose button for a drug delivery device according to claim 1 , wherein the surface of the dose button is milled or lathed.3. Dose button for a drug delivery device according to claim 1 , wherein the material used for the dose button comprises metal.4. Dose button for a drug delivery device according to claim 3 , wherein the metal is steel or aluminium.5. Dose button for a drug delivery device according to claim 1 , wherein the surface of the dose button has a specific structure.6. Dose button for a drug delivery device according to claim 5 , wherein the surface structure of the dose button is indicative for the drug contained in the drug delivery device.7. Dose button for a drug delivery device according to claim 5 , wherein the surface structure of the dose button forms a pattern.8. Dose button for a drug delivery device according to claim 1 , wherein the dose button is firmly connected with the drug delivery device.9. Dose button for a drug delivery device claim 1 , according to claim 1 , wherein the surface of the dose button is coloured.10. Drug delivery device comprising a dose button according to claim 1 , which is reusable.11. Drug delivery device according to claim 10 , wherein a drug is held in a cartridge of the device.12. Drug delivery device according to claim 11 , wherein the drug is a pharmaceutical formulation ...

DRUG DELIVERY DEVICE AND METHOD OF MANUFACTURING A DRUG DELIVERY DEVICE

The present invention relates to drug delivery device and a and method of manufacturing a drug delivery device with a housing having a proximal end and a distal end, a cartridge adapted to accommodate a drug, a cartridge retaining member adapted to retain the cartridge, the cartridge retaining member being secured to the housing, and a spring washer being arranged within the housing so as to exerting a force on the cartridge and securing the cartridge against movement with respect to the cartridge retaining member and against movement with respect to the housing. 1. A drug delivery device comprising:a housing with a proximal end and a distal end,a cartridge adapted to accommodate a drug,a cartridge retaining member adapted to retain the cartridge, the cartridge retaining member being secured to the housing, characterized in that a first spring washer is arranged within the housing so as to exert a force on the cartridge and to secure the cartridge against movement with respect to the cartridge retaining member, the first spring washer being arranged so as to abut the cartridge on a side of the cartridge that faces the proximal end of the housing, and in that a second spring washer is provided, preferably arranged on the proximal side of the first spring washer.2. The drug delivery device according to claim 1 , wherein the first spring washer is biased so as to exert the force on the cartridge in the distal direction.3. The drug delivery device according to claim 1 , wherein the first spring washer is secured against axial movement with respect to the housing.4. The drug delivery device according to claim 1 , wherein the drug delivery device comprises a piston rod for dispensing a dose of the drug from the device when the piston rod is driven in the distal direction and wherein the first spring washer and the second spring washer each comprise an opening claim 1 , the opening being arranged so as to allow the piston rod to run through the opening.5. The drug delivery ...

Medication Delivery Device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device. 1. A medication delivery device comprising:a housing having a proximal and a distal end,a medication receptacle designed to be engaged with the housinga piston rod which is moveable in a distal direction for medication delivery anda drive device for rotating the piston rod in a first rotational direction and thereby moving the piston rod in the distal direction for medication delivery;characterized in thatthe piston rod comprises two threaded sections, wherein a first threaded section is provided for threaded engagement with a reset element and a second threaded section is provided for threaded engagement with the drive device and wherein the threads in the first and second threaded sections are oppositely disposed, whereinin an operational state the reset element is prevented from rotation with respect to the housing, the piston rod thereby being prevented from moving in a proximal direction, andin a resetting state the reset element is allowed to rotate with respect to the housing, the medication delivery device being resettable by rotating the piston rod and the reset element in a second rotational direction and moving the piston rod in the proximal direction.2. The medication delivery device according to claim 1 , characterized in thatwhen the medication receptacle is engaged with the distal end of the housing the reset element is in the operational state andwhen the medication receptacle is disengaged from the distal end of the housing the reset element is in the resetting state.3. The medication delivery device according to claim 1 , characterized in that ...

System for Modelling the Conversion of Lignocellulosic Materials

A system for modelling the conversion of crystalline insoluble cellulose to ethanol is provided which includes a processor configured to calculate the production rate for ethanol based on a number of inputs and as a function of specific equations. The system can form part of a control system for controlling the operation of a plant which produces ethanol from cellulose. 2. A system as claimed in wherein the calculated production rate for ethanol is used to adjust process parameters.3. A system as claimed in wherein the processor solves the equations (1) to (10) iteratively.4. A system as claimed in wherein the processor has a feedback loop which includes the further input of a measured rate of formation of enzyme-substrate complexes.5. A system as claimed in wherein a still further input to the processor of supplied oxygen is provided.8. A control system for a biofuels plant characterized in that it includes a processor substantially as claimed in and which further includes means for controlling at least some operations of the plant to achieve user determined ethanol production rates based on measurements made within the plant. This invention relates to a system for modelling the conversion of lignocellulosic materials. More particularly, the invention relates to a system for modelling crystalline cellulose hydrolysis via the activity of cellulase enzymes to release monomeric sugars.Approximately 1.3×10metric tons (dry weight) of terrestrial plants are produced annually on a worldwide basis. Plant biomass consists of about 40% to 55% cellulose, 25% to 50% hemicellulose and 10% to 40% lignin, depending on whether the source is hardwood, softwood, or grasses. Cellulose is the major polysaccharide present, and is a water-insoluble glucan polymer that contains the major fraction of the fermentable sugar glucose.Native cellulose consists of amorphous and crystalline regions and it is predominantly the former region that is prone to enzymatic attack. The major types of ...

Coded Cartridge Holder System for a Fluid Delivery Device

A coded cartridge holder system is disclosed for use with a cartridge assembly () containing a fluid and a delivery device (), where the system has keyed connectors (′) to prevent accidental attachment of the wrong fluid delivery device (). The system comprises a coupling () attachable to the dose setting portion () of the device () and keyed to the proximal end of the cartridge holder (). The cartridge holder () may also contain medical coding () to correspond to matching coding (′) on the distal end of a cartridge assembly (). 1. A coded cartridge holder system comprising:a coupling having a proximal end, a distal end, and an inner wall, the inner wall comprising a plurality of keyed connectors and the proximal end being configured for attachment to a dose setting portion of a fluid delivery device,a cartridge holder comprising corresponding keyed connectors which are adapted and arranged to match the keyed connectors provided on the coupling, wherein the cartridge holder comprises a distal end, the distal end comprising an interior wall comprising a mechanical coding, wherein the mechanical coding comprises three equally spaced protrusions and a fourth protrusion offset an angle β from one of the three equally spaced protrusions, anda cartridge comprising a distal end, wherein the distal end comprises three equally space radial slots and a fourth slot offset from one of the three equally spaced slots by an angle equal to β, the slots being configured to match the mechanical coding provided on the interior wall of the cartridge holder.2. The coded cartridge holder system according to claim 1 ,wherein the inner wall is configured to define a bore that extends from the proximal end to the distal end.3. The coded cartridge holder system according to claim 1 ,wherein the keyed connectors are provided on the distal end of the inner wall.4. The coded cartridge holder system according to claim 1 ,wherein the cartridge holder comprises a proximal end, the corresponding ...

Producing rigid polymer foams

A process for producing a rigid polymer foam comprises reacting components A to C in the presence of component D or an isocyanate-functional prepolymer of components A and B with component C in the presence of component D, the total amount of which is 100 wt %, (A) 35 to 65 wt % of at least one polyisocyanate component A, (B) 5 to 50 wt % of at least one polyol component B, (C) 1 to 59 wt % of at least one polycarboxylic acid component C, and (D) 0.01 to 3 wt % of at least one Lewis base component D, wherein the reaction takes place with release of carbon dioxide.

Medication Delivery Device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device. 129-. (canceled)31. The medication delivery device according to claim 30 ,wherein, in the guiding position, the guiding element is prevented from rotation with respect to the housing.32. The medication delivery device according to claim 30 ,wherein, when the guiding element is in the guiding position, the piston rod can be moved axially in the distal direction with respect to the housing.33. The medication delivery device according to claim 32 ,wherein the piston rod is prevented from axial movement in the proximal direction with respect to the housing.34. The medication delivery device according to claim 30 ,wherein when the guiding element is not in the guiding position, the piston rod is free to move axially in the proximal direction with respect to the housing.35. The medication delivery device according to claim 30 ,wherein the first and second engagement features are designed such that for moving the medication receptacle and the housing into engagement, the actuation element is rotated and moved axially with respect to the housing andare thereafter rotated without being moved axially, thereby bringing the guiding element in the guiding position.36. The medication delivery device according to claim 30 ,wherein the guiding element is a nut that is threadedly engaged with the piston rod.37. The medication delivery device according to claim 30 , whereinthe drive device comprises a drive sleeve andthe piston rod comprises two threaded sections, wherein a first threaded section isprovided for threaded engagement with the guiding element and a second ...

DRUG DELIVERY DEVICE AND CARTRIDGE HOLDER FOR A DRUG DELIVERY DEVICE

A drug delivery device is provided comprising a cartridge holder comprising at least one guide track, and a body comprising at least one interaction member adapted and arranged to mechanically cooperate with the at least one guide track. The guide track comprises a first section and a second section, wherein the path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the path defined by the first section with the longitudinal axis is smaller than the angle which is enclosed by the path defined by the second section with the longitudinal axis, wherein, for connecting the cartridge holder to the body, the interaction member is configured to mechanically cooperate with the first section such that the cartridge holder is axially moved and rotated with respect to the body, and the interaction member is configured to mechanically cooperate with the second section such that the cartridge holder is rotated with respect to the body, whereby an axial movement of the cartridge holder with respect to the body is prevented. Furthermore, a cartridge holder for a drug delivery device is provided. 114-. (canceled)15. A drug delivery device comprisinga cartridge holder comprising at least one guide track,a body comprising at least one interaction member adapted and arranged to mechanically cooperate with the at least one guide track,wherein the guide track comprises a first section and a second section, wherein the path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the path defined by the first section with the longitudinal axis is smaller than the angle which is enclosed by the path defined by the second section with the longitudinal axis,wherein, for connecting the cartridge holder to the body, the interaction member is configured to mechanically cooperate with the first section such that the cartridge ...

Drive Assembly for a Drug Delivery Device and Corresponding Drug Delivery Device

A drive assembly for a drug delivery device is disclosed. The drive assembly is connectable with a cartridge holder and comprises a housing, a piston rod, the piston rod being movable in a distal direction for drug delivery, and a guide nut, the guide nut being rotatable relative to the housing around an axis of the assembly and provided for guiding the piston rod. A locking means is provided which is enabled to take an engaged state in which the locking means is engaged with the guide nut in order to prevent rotation of the guide nut and to take a disengaged state in which the locking means is disengaged from the guide nut in order to allow rotation of the guide nut. Moreover, a coupling means is provided, the coupling means being rotatable relative to the housing around the axis of the assembly for interaction with the locking means in order to change between the engaged state and the disengaged state of the locking means.

NEEDLE HUB AND NEEDLE

The invention is related to an apparatus comprising a needle hub comprising at least one channel configured to guide a liquid, especially a liquid drug component, a needle comprising a cannula configured to guide the liquid and a plate fixedly connected to one end of the cannula, wherein the plate is configured to interact with the needle hub for fixing the needle to the needle hub. The invention further is related to an apparatus comprising a cannula configured to guide a liquid, especially a liquid drug component, and a plate fixedly connected to one end of the cannula. 15-. (canceled)6. An apparatus comprisinga needle hub comprising at least one channel configured to guide a liquid, especially a liquid drug component,and a needle comprising a cannula configured to guide a liquid, especially a liquid drug component, and a plate fixedly connected to one end of the cannula.{'b': 304', '314', '324', '336', '338, 'wherein the plate (, ; ; , ) fixed to the cannula is configured to interact with the needle hub for fixing the needle to the needle hub.'}7. Apparatus according to claim 6 , wherein the plate is configured to be mounted in an indentation of a needle hub.8. The Apparatus according to claim 6 , wherein the needle hub comprises two halves configured to be fixedly connected to each other.9. The Apparatus according to claim 8 , wherein at least on half of the needle hub comprises an indentation configured to receive the plate at least partially.10. The Apparatus according to claim 6 , wherein the plate is configured to orientate the needle relative to the needle hub. The present application is a U.S. National Phase Application pursuant to 35 U.S.C. §371 of International Application No. PCT/EP2012/058260 filed May 4, 2012, which claims priority to European Patent Application No. 11165121.2 filed May 6, 2011. The entire disclosure contents of these applications are herewith incorporated by reference into the present application.The present patent application ...

Weight Selection with Alignment Indicia

A weightlifting apparatus has at least one indicia on at least one weight plate indicating the amount of weight of the weight plate. The barbell of the weightlifting apparatus can have alignment indicia on an outer surface thereon. The weightlifting apparatus is configured to selectively chose to display the amount of weight on the weightlifting apparatus. The alignment indicia of the barbell is aligned with the at least one indicia on the weight plate to mark or indicate which indicia of a plurality of indicia is the selected indicia to be viewed. 1. A weight training apparatus comprising:at least one weight member having a first side, a second side and an outer surface having a width extending between the first and second sides; andat least one indicia disposed on the outer surface to indicate the weight of the at least one weight member.2. The weight training apparatus of further comprising an elongate member with an outer surface having at least one alignment indicia.3. The weight training apparatus of further comprising an elongate member with an outer surface having indicia indicating the weight of only the elongate member.4. The weight training apparatus of claim 1 , wherein the at least one indicia is at least one of a marking claim 1 , a language claim 1 , a number claim 1 , a symbol claim 1 , and a letter.5. The weight training apparatus of claim 1 , wherein a plurality of indicia are arranged in any order claim 1 , sequence claim 1 , series claim 1 , color or pattern on the outer surface of the weight member.6. The weight training apparatus of claim 1 , wherein a plurality of indicia is disposed around the circumference of the outer surface of the weight member.7. The weight training apparatus of claim 1 , wherein a plurality of indicia is disposed around only a portion of the circumference of the outer surface of the weight member.8. The weight training apparatus of claim 1 , wherein a plurality of indicia are equally spaced apart from each other around ...

ELECTRICALLY CONDUCTIVE PARTICLE FOAMS BASED ON THERMOPLASTIC ELASTOMERS

Foam beads based on thermoplastic elastomers and having a coating comprising at least one electrically conductive substance, processes for producing same by coating the foam beads with an emulsion of a conductive substance in a plasticizer, and also processes for producing bead foams by joining the foam beads together thermally via high-frequency electromagnetic radiation. 1: Foam beads based on thermoplastic elastomers and having a coating comprising at least one electrically conductive substance.2: The foam beads according to claim 1 , comprising a thermoplastic polyurethane.3: The foam beads according to claim 1 , wherein the coating consists of graphite.4: The foam beads according to claim 1 , having a bulk density ranging from 30 to 250 kg/m.5: The foam beads according to claim 1 , wherein a proportion of the at least one electrically conductive substance ranges from 0.1 to 1 wt % claim 1 , based on the foam beads.6: A process for producing the foam beads of claim 1 , the process comprising coating foam beads with an emulsion of a conductive substance in a plasticizer selected from the group consisting of a phthalate claim 1 , an alkylsulfonic ester claim 1 , a polyether claim 1 , a polyurethane claim 1 , a low molecular weight polyamide claim 1 , a citric ester claim 1 , an adipic ester claim 1 , a diisononyl 1 claim 1 , 2-cyclohexanedicarboxylate and a glycerol ester.7: The process according to claim 6 , wherein foam beads of a thermoplastic polyurethane are coated with an emulsion of graphite in 1 claim 6 ,2 claim 6 ,3-propanetriol triacetate.8: A process for producing bead foams claim 1 , the process comprising joining the foam beads of together thermally using high-frequency electromagnetic radiation.9: The process according to claim 8 , wherein the foam beads are joined thermally using microwaves in a frequency range between 100 MHz and 300 GHz.10: A bead foam obtainable by the process according to claim 8 , wherein the bead foam has a specific volume ...

POLYURETHANE PARTICLE FOAM WITH POLYURETHANE COATING

The present invention relates to coated shaped articles comprising at least one shaped article comprising foamed beads comprising at least one polyurethane (A) and at least one coating comprising at least one polyurethane (B), wherein polyurethane (A) and polyurethane (B) are each constructed from at least one polyol and at least one polyisocyanate and wherein not less than 50 wt % of the polyol component used for constructing polyurethane (A) and polyurethane (B) is identical and not less than 50 wt % of the at least one polyisocyanate component used for constructing polyurethane (A) and polyurethane (B) is identical. The present invention further relates to processes for producing the coated shaped articles of the present invention and also to the method of using the coated shaped articles of the present invention for various applications. 1. A coated shaped article comprising(a) at least one shaped article comprising foamed beads comprising at least one polyurethane (A) and(b) at least one coating comprising at least one polyurethane (B),wherein polyurethane (A) and polyurethane (B) are each constructed from at least one polyol and at least one polyisocyanate and wherein not less than 50 wt % of the polyol component used for constructing polyurethane (A) and polyurethane (B) is identical and not less than 50 wt % of the at least one polyisocyanate component used for constructing polyurethane (A) and polyurethane (B) is identical.2. The shaped article according to claim 1 , wherein not less than 85 wt % of the polyol component used for constructing polyurethane (A) and polyurethane (B) is identical and not less than 85 wt % of the at least one polyisocyanate component used for constructing polyurethane (A) and polyurethane (B) is identical.3. The shaped article according to claim 1 , wherein the at least one polyurethane (A) is a thermoplastic polyurethane.4. The shaped article according to claim 1 , wherein the at least one polyurethane (B) is a thermoplastic ...

Drug Delivery Device with Restricted Cap Replacement

The present disclosure relates to a drug delivery device that has a housing and a cap. The drug delivery device also has a lock that prevents the cap being fully replaced on the housing after the cap has been removed. 120-. (canceled)21. A drug delivery device comprising:a housing configured to receive a needle;a cap removably attached to the housing to cover the needle; anda locking member comprising a proximal end and a distal end, the locking member connected to the cap at the distal end of the locking member and extending proximally from a wall of the cap, the locking member movable relative to the wall of the cap to a locking position when the cap is removed from the housing, the locking member in the locking position being configured to prevent the cap from being attached to the housing.22. The drug delivery device of claim 21 , wherein the proximal end of the locking member is a free end of the locking member.23. The drug delivery device of claim 22 , wherein the free end of the locking member comprises a proximally facing surface configured to claim 22 , in the locking position of the locking member claim 22 , abut a portion of the housing to prevent the cap from being attached to the housing.24. The drug delivery device of claim 21 , wherein the locking member is configured such that the locking member extends inwardly relative to the wall of the cap when the locking member is in the locking position.25. The drug delivery device of claim 21 , further comprising:a hinge connecting the locking member to the cap,wherein the locking member is movable about the hinge to the locking position.26. The drug delivery device of claim 25 , wherein the hinge is formed by a notch in the wall of the cap.27. The drug delivery device of claim 21 , wherein the locking member is resiliently biased toward the locking position.28. The drug delivery device of claim 21 , wherein the proximal end of the locking member is configured to push against the housing when the cap is ...

DRUG DELIVERY DEVICE

A mechanism in the body is used to drive a piston rod and comprises means for guiding the movement of the piston rod relatively to the body while delivering the drug. Further means are provided for releasing the piston rod from the means for guiding the movement, thus enabling a reset of the piston rod to a start position, especially after the receptacle has been emptied and is to be refilled. The device is constructed in such a manner that a reset of the piston rod is facilitated. 1. A drug delivery device , comprising:a two-part housing comprising a distal part and a proximal part, where the distal part is removable from the proximal part and is configured as a receptacle to hold a removable cartridge containing a drug;a piston rod operatively located in the proximal part and having a weight associated therewith, the piston rod being movable relative to the housing through axial movement of an operation button in a distal direction to cause a portion of the drug to expel out of the cartridge when the piston rod moves in the distal direction, where the piston rod has a start position with respect to the proximal part prior to expulsion of a first portion the drug from the cartridge; a reset nut;', 'a lock nut;', 'a spring; and', 'a piston rod nut,, 'a reset mechanism located in a distal end of the proximal part, the reset mechanism comprising,'}wherein the reset nut guides the movement of the piston rod distally relative to the housing each time a portion of the drug is expelled from the cartridge until an end positioned of the piston rod is reached, where the reset nut is fixed axially relative to the body during the expulsion of the drug,wherein the resetting of piston rod proximally back to the start position is caused by the orientating the body such that the weight of the piston rod in combination with gravity causes the piston rod to retract into the body to the start position.2. The drug delivery device according to claim 1 , where the piston rod further ...

VALVE MECHANISM

The invention provides a medical device having a valve mechanism which has an effective sealing, is simple and cost-saving to produce and at the same time provides an improved pressure control. Additionally, an improved biocompatibility can be provided. The medical device comprises a channel and at least one valve element. The channel comprises at least two openings, and the valve element comprises at least one sealing area. The valve element can be brought in a closed state, such that the sealing area of the valve element seals one of the openings of the channel and the valve element is at least in part flexible, such that the valve element can be brought into an open state by the pressure of a medium inside the channel and the medium can exit the channel between the valve element and the channel. 114-. (canceled)15. A medical device , comprising:a channel comprising at least two openings,a valve element comprising at least one sealing area,wherein said valve element is at least in part flexible,wherein said valve element is configured to have a closed state, in which said sealing area of said valve element seals one of said openings of said channel,wherein said valve element is further configured to have an open state, such that said valve element can be brought into said open state by the pressure of a medium inside said channel, and said medium can exit said channel between said valve element and said channel andwherein said valve element is at least partially made of metal.16. The medical device according to claim 15 , wherein the sealing area of said valve element claim 15 , when in said closed state claim 15 , seals said opening of said channel by direct contact with said channel.17. The medical device according to claim 15 , wherein said sealing area of said valve element by the pressure of said medium inside said channel can be bent in the axial direction of said channel and away from said channel.18. The medical device according to claim 15 , wherein said ...

AUTO-INJECTOR DEVICE

An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element. 1. An auto-injector device comprising:a medicament reservoir;a stopper for expelling a medicament out of the medicament reservoir;a driving element, formed from a shape memory alloy, which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when a temperature of the driving element is raised above a shape change temperature, so as to drive the stopper through the medicament reservoir; anda heating mechanism configured to actively heat the driving element, wherein the heating mechanism is a chemical heating element configured to generate heat through an exothermic process, wherein the exothermic process is an exothermic rehydration of a dehydrated salt.2. The auto-injector device of claim 1 , wherein the first configuration of the driving element is a compressed coil shape claim 1 , and the second configuration of the driving element is an expanded coil shape.3. The auto-injector device of claim 1 , wherein the shape memory alloy is a nickel-titanium alloy.4. The auto-injector device ...

Drug-Filled Stents With Filaments for Increased Lumen Surface Area and Method of Manufacture Thereof

A stent including a hollow wire formed into a stent pattern. The hollow wire includes an outer member having an outer surface and an inner surface, a lumen extending longitudinally within the hollow wire, at least one opening extending from the outer surface of the outer member to the lumen, and a plurality of filaments extending longitudinally within the lumen. The plurality of filaments increases the amount of surface area available for tissue in-growth within the lumen. Each filament of the plurality of filaments is spaced from adjacent filaments of the plurality of filaments, and the spacing between adjacent filaments of the plurality of filaments is configured to permit tissue in-growth between the adjacent filaments. 1. A stent comprising: an outer member having an outer surface and an inner surface;', 'a lumen extending longitudinally within the hollow wire;', 'at least one opening disposed through the outer member to the lumen; and', 'at least one filament extending longitudinally within the lumen,, 'a hollow wire formed into a stent pattern, wherein the hollow wire includeswherein the at least one filament increases the amount of surface area available for tissue in-growth within the lumen.2. The stent of claim 1 , wherein the at least one filament extends a full length of the hollow wire.3. The stent of claim 1 , wherein the at least one filament has a circular cross-section.4. The stent of claim 1 , further comprising a plurality of filaments extending longitudinally within the lumen claim 1 , wherein each filament of the plurality of filaments is spaced from an adjacent filament of the plurality of filaments.5. The stent of claim 4 , wherein the plurality of filaments includes at least ten filaments.6. The stent of claim 1 , wherein the lumen is defined by the inner surface of the outer member and extends longitudinally within the outer member.7. The stent of claim 1 , wherein the outer member is formed from a cobalt-chromium alloy.8. The stent of claim ...

Polyurethane particle foam with polyurethane coating

Coated shaped articles contain at least one shaped article with foamed beads containing at least one polyurethane (A) and at least one coating containing at least one polyurethane (B), wherein polyurethane (A) and polyurethane (B) are each constructed from at least one polyol and at least one polyisocyanate and wherein not less than 50 wt % of the polyol component used for constructing polyurethane (A) and polyurethane (B) is identical and not less than 50 wt % of the at least one polyisocyanate component used for constructing polyurethane (A) and polyurethane (B) is identical. Processes for producing the coated shaped articles and the method of using the coated shaped articles for various applications can be utilized.

AN AUTO-INJECTOR DEVICE

An auto-injector device comprises a stopper for expelling a medicament out of a medicament reservoir; a driving element which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when the temperature of the driving element is raised above a shape change temperature, so as to drive the stopper of the syringe mechanism through the medicament reservoir; and a heating mechanism configured to actively heat the driving element. The heating mechanism is a chemical heating element configured to generate heat through an exothermic process or comprises a fluid reservoir for retaining a fluid; a heater configured to heat the fluid in the fluid reservoir; a pump configured to expel the fluid out of the fluid reservoir; and a connecting conduit arranged to carry the fluid from the fluid reservoir to the driving element. 115-. (canceled)16. An auto-injector device comprising:a medicament reservoir;a stopper for expelling a medicament out of the medicament reservoir;a driving element, formed from a shape memory alloy, which has a first configuration and a second configuration and is configured to change shape from the first configuration to the second configuration when a temperature of the driving element is raised above a shape change temperature, so as to drive the stopper through the medicament reservoir; anda heating mechanism configured to actively heat the driving element, wherein the heating mechanism is a chemical heating element configured to generate heat through an exothermic process.17. The auto-injector device of claim 16 , wherein the first configuration of the driving element is a compressed coil shape claim 16 , and the second configuration of the driving element is an expanded coil shape.18. The auto-injector device of claim 16 , wherein the exothermic process is an exothermic crystallisation of a supersaturated solution.19. The auto-injector device of claim 16 , wherein ...

DRUG DELIVERY DEVICE

A drug delivery device for setting and dispensing a dose of a drug is presented having a support body having a first end defining a first opening and a second end defining a second opening and a centered outer indicator ring. A syringe barrel sealed by a stopper is slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, wherein the syringe barrel is positioned within the support body. A needle shield is adapted to be coupled to one of the ends of the support body and slidably disposed thereon. An outer body is adapted to be coupled to the other end of the support body and slidably disposed thereon, wherein the outer indicator ring limits the movement of the outer body as well as of the needle shield. 115-. (canceled)16. Drug delivery device for setting and dispensing a dose of a drug , comprising:a support body having a first end defining a first opening and a second end defining a second opening and a centered outer indicator ring,a syringe barrel sealed by a stopper slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, wherein the syringe barrel is positioned within the support body,a needle shield adapted to be coupled to one of the ends of the support body and slidably disposed thereon;an outer body adapted to be coupled to the other end of the support body and slidably disposed thereon;wherein the outer indicator ring limits the movement of the outer body as well as of the needle shield.17. Drug delivery device according to claim 16 , wherein the outer indicator ring is curved.18. Drug delivery device according to claim 16 , wherein a first detent mechanism is arranged to constrain movement of the outer body relative to the support body by opposing this movement with a first detent force.19. Drug delivery device according to claim 16 , wherein a second detent mechanism is arranged to constrain movement of ...

Method and system for controlling the conversion of lignocellulosic materials

The invention provides a method and system for controlling the conversion of crystalline insoluble cellulose to an organic product in a bioreactor containing crystalline insoluble cellulose and a culture medium. A processor of a computing device receives an input from a sensor in the bioreactor. The input may be a measurement of one or more of concentration, temperature, pH and pressure. The processor calculates conversion of cellulose using the input to provide a total calculated organic product in the bioreactor. The processor receives a further input from a sensor in the bioreactor of the total actual organic product and compares the total calculated organic product and the total actual organic product. The processor then transmits an instruction to an agitator associated with the bioreactor to control agitation of the content of the bioreactor if the total actual organic product is outside a predetermined range of the total calculated organic product.

ISOCYANATE-EPOXY-FOAM SYSTEM

The present invention relates to a method for producing a rigid foam, which comprises reacting at least one polyisocyanate with a mixture comprising at least one polyepoxide, water, and at least one other hydrogen-acidic compound, the reaction taking place in the presence of a metal-free Lewis base having at least one nitrogen atom, to rigid foams obtainable by such a method, and to the use of a rigid foam of the invention for producing insulating materials, vacuum insulation panels, refrigeration equipment, construction elements, wind rotor blades, or elements for boatbuilding and vehicle construction. 1: A method for producing a rigid foam , the method comprising:reacting at least one polyisocyanate with a mixture comprising at least one polyepoxide, water, and at least one other hydrogen-acidic compound, the reaction taking place in the presence of a catalyst, which is a metal-free Lewis base comprising at least one nitrogen atom,wherein the catalyst is selected from the group consisting of 1,8-diazabicyclo-5,4,0-undecen-7-ene, N-methyl-N′-(dimethylaminomethyl)piperazine, pentamethyldiethylenetriamine, methylimidazole, and a mixture and a derivative thereof.2: The method according to claim 1 , wherein the at least one other hydrogen-acidic compound is selected from the group consisting of a polyol and a polyamine.3: The method according to claim 1 , wherein the polyepoxide is used in an amount in a range from 5 to 70 wt % claim 1 , based on a sum of the polyepoxide and the at least one other hydrogen-acidic compound used.4: The method according to claim 1 , wherein the catalyst is a tertiary amine.5: The method according to claim 1 , wherein the catalyst is selected from the group consisting of 1 claim 1 ,8-diazabicyclo-5 claim 1 ,4 claim 1 ,0-undecen-7-ene claim 1 , and a derivative thereof.6: The method according to claim 1 , wherein the catalyst is used in an amount in a range from 0.01 to 2 wt % claim 1 , based on a sum of the polyisocyanate and of the ...

SYSTEMS AND METHODS FOR STANDARDIZING INTERFACES FOR THIRD PARTY INTEGRATION

A computer-implemented method for performing data integration, the method comprising establishing a connection between a first application and a first remote database, wherein the connection is established using a connection file containing metadata required to establish the connection, requesting, by the first application, data from the first remote database that stores the data in a first format, wherein the metadata is used to determine whether the first application is authorized to access the data in the first remote database, importing the data in the first format from the first remote database, converting, by the first application, the data in the first format to data in a native format that is specific to the first application, and providing the data in the native format to a user of the first application. 1. A computer-implemented method for performing data integration , the method comprising:establishing a connection between a first application and a first remote database, wherein the connection is established using a connection file containing metadata required to establish the connection;requesting, by the first application, data from the first remote database that stores the data in a first format, wherein the metadata is used to determine whether the first application is authorized to access the data in the first remote database;importing the data in the first format from the first remote database;converting, by the first application, the data in the first format to data in a native format that is specific to the first application; andproviding the data in the native format to a user of the first application.2. The method of claim 1 , further comprising establishing a second connection between the first application and a second remote database while the first application is still connected to the first remote database.3. The method of claim 2 , wherein the second remote database stores data in a second format claim 2 , and the method further comprises ...

DRUG DELIVERY DEVICE AND CARTRIDGE HOLDER FOR A DRUG DELIVERY DEVICE

A drug delivery device is provided comprising a cartridge holder comprising at least one guide track, and a body comprising at least one interaction member adapted and arranged to mechanically cooperate with the at least one guide track. The guide track comprises a first section and a second section, wherein the path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the path defined by the first section with the longitudinal axis is smaller than the angle which is enclosed by the path defined by the second section with the longitudinal axis, wherein, for connecting the cartridge holder to the body, the interaction member is configured to mechanically cooperate with the first section such that the cartridge holder is axially moved and rotated with respect to the body, and the interaction member is configured to mechanically cooperate with the second section such that the cartridge holder is rotated with respect to the body, whereby an axial movement of the cartridge holder with respect to the body is prevented. Furthermore, a cartridge holder for a drug delivery device is provided. 1. A drug delivery device comprisinga cartridge holder comprising at least two guide tracks each having the same configuration,a body having an inner surface comprising at least two protrusions each adapted and arranged to mechanically cooperate with the guide tracks,wherein each guide track comprises a first section and a second section, wherein a first path which is defined by the first section encloses an angle with the longitudinal axis of the device, wherein the angle which is enclosed by the first path with the longitudinal axis is smaller than the angle which is enclosed by a second path defined by the second section with the longitudinal axis,wherein, for connecting the cartridge holder to the body, the protrusions are configured to mechanically cooperate with the first section such that the ...

Web-Based Spreadsheet Interaction with Large Data Set

A computer-implemented method for presenting data is disclosed. The method includes receiving at a data server sub-system, from a browser on a remote client computing system, a request for data stored in a central data store; retrieving the requested data from the central data store and providing data corresponding to the requested data to a spreadsheet presentation sub-system that is in communication with the data server sub-system and with the browser on the remote client computing system; and providing a document key to the browser on the remote client computing system so that the browser can request from the presentation sub-system a spreadsheet document that displays the data corresponding to the requested data. 122-. (canceled)23. A method comprising:providing, by a data server system to a spreadsheet server system, access to data stored in a data store;populating, at the spreadsheet server system, a spreadsheet document based on the data;providing, by the data server system to a browser on a client computing system, a time stamp associated with a time of populating the spreadsheet document and a document key identifying the spreadsheet document;receiving, at the spreadsheet server system from the browser, changes to the spreadsheet document;obtaining, by the data server system from the spreadsheet server system, the changes based on the time stamp; andapplying, at the data server system, the changes to the data store.24. The method of claim 23 , further comprising:converting the changes into a format for storing in the data store.25. The method of claim 23 , wherein the spreadsheet server compares the time stamp with another time stamp corresponding to an initiation of a save command.26. The method of claim 23 , further comprising:identifying errors in the data, wherein the spreadsheet server system communicates the errors to the browser.27. The method of claim 23 , wherein the spreadsheet server system generates the time stamp.28. The method of claim 23 , ...

COMBINATION FOAM

The combination foam comprises a matrix composed of polyurethane foam and foamed particles of thermoplastic polyurethane comprised therein, where matrix and particles are each made up of polyol components and polyisocyanate components, wherein at least 50% by weight of the basic building blocks forming the polyol component of the matrix and particles are identical and at least 50% by weight of the basic building blocks forming the polyisocyanate component of the matrix and particles are identical. 1. A combination foam , comprising:a matrix comprising polyurethane foam; andfoamed particles of thermoplastic polyurethane comprised therein,wherein the matrix and the particles each comprise polyol components and polyisocyanate components, wherein at least 50% by weight of the basic building blocks forming the polyol component of the matrix and particles are identical and at least 50% by weight of the basic building blocks forming the polyisocyanate component of the matrix and particles are identical, whereby the matrix is completely open-cell and the foamed particles in the matrix are at least partly closed-cell.2. The combination foam according to claim 1 , wherein at least 60% by weight of the basic building blocks forming the polyol component of the matrix and particles are identical and at least 60% by weight of the basic building blocks forming the polyisocyanate component of the matrix and particles are identical.3. The combination foam according to claim 2 , wherein at least 65% by weight of the basic building blocks forming the polyol component of the matrix and particles are identical and at least 85% by weight of the basic building blocks forming the polyisocyanate component of the matrix and particles are identical.4. The combination foam according to claim 1 , wherein the foamed particles have a diameter of from 0.1 mm to 10 cm claim 1 , and are spherical or ellipsoidal.5. The combination foam according to claim 1 , wherein the foamed particles have a ...

Drive Unit for a Liquid Handling Device and Liquid Handling Device

A drive unit for a medical device includes a drive unit housing, a drive member retained in the drive unit housing and movable relative to the drive unit housing to drive an operation of the medical device, the drive member includes a coupler output portion configured to be operatively connected to a liquid handling unit, a drive mechanism retained in the drive unit housing, wherein the drive mechanism is coupleable or coupled to the drive member via a mechanism interface and is configured to transfer a driving force or torque to the drive member, and a sealing member provided to establish a sealed interface with the drive member, wherein the sealed interface defines a sealed section of the interior of the drive unit housing, wherein the mechanism interface is arranged within the sealed section and the coupler output portion is arranged outside of the sealed section. 116-. (canceled)17. A drive unit for a medical device , comprising:a drive unit housing;a drive member retained in the drive unit housing and movable relative to the drive unit housing to drive an operation of the medical device, the drive member comprising a coupler output portion configured to be operatively connected to a liquid handling unit;a drive mechanism retained in the drive unit housing, wherein the drive mechanism is coupleable to the drive member via a mechanism interface and configured to transfer a driving force or torque to the drive member; anda sealing member configured to establish a sealed interface with the drive member, wherein the sealed interface defines a sealed section of an interior of the drive unit housing,wherein the mechanism interface is arranged within the sealed section and the coupler output portion is arranged outside of the sealed section.18. The drive unit of claim 17 , wherein the drive member is axially movable relative to the sealing member from a first position to a second position and the drive unit comprises a biasing mechanism configured to bias the drive ...

Drug Delivery Device

The invention relates to a drug delivery device for setting and dispensing a dose of a drug, comprising: a support body having a first end defining a first opening and a second end defining a second opening, the support body configured to retain a syringe barrel sealed by a stopper slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly, a needle shield adapted to be coupled to one of the ends of the support body, slidably disposed thereon and keyed to the support body for preventing relative rotation, wherein at least one guiding track is defined on the support body and at least one retaining clip arranged on the needle shield is deflectable by the guiding track, wherein the guiding track is configured such that the retaining clip follows a first path when the needle shield is depressed from an extended position to a retracted position for needle extension and that the retaining clip follows a different second path when the needle shield is subsequently extended, wherein a non-return catch is arranged for catching the retaining clip at the end of the second path. 115-. (canceled)16. Drug delivery device for setting and dispensing a dose of a drug , comprising:a support body having a first end defining a first opening and a second end defining a second opening, the support body configured to retain a syringe barrel sealed by a stopper slidably disposed therein along an axial direction and adapted to have an integrated needle or to be coupled with a needle assembly,a needle shield adapted to be coupled to one of the ends of the support body, slidably disposed thereon and keyed to the support body for preventing relative rotation, wherein at least one guiding track is defined on the support body and at least one retaining clip arranged on the needle shield is deflectable by the guiding track, wherein the guiding track is configured such that the retaining clip follows a first path when the ...

Assembly for a Drug Delivery Device

An assembly for a drug delivery device is provided the assembly comprising a cartridge adapted and arranged to contain at least one dose of a drug, a bung being slidably arranged within the cartridge, a housing comprising a distal end and a proximal end, and a piston rod adapted and arranged for moving the bung in the distal direction with respect to the housing for dispensing a dose of the drug. The assembly further comprises a drive member and arranged for transferring movement to the piston rod for dispensing the dose, and an engagement member configured to mechanically cooperate with the piston rod and with the housing. The engagement member is moveable between a reset position, where the engagement member is allowed to rotate with respect to the housing, and an operating position, where the engagement member is rotationally locked with respect to the housing, wherein the assembly is configured such that the engagement member is rotated and simultaneously axially displaced during movement of the engagement member between the operating position and the reset position. The engagement member and the housing are threadedly engaged with one another, wherein at least one of the engagement member and the housing comprises a thread and the other one of the engagement member and the housing comprises an interaction. Furthermore, the use of an engagement member for a drug delivery device is described.

ASSEMBLY FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE

An assembly for a drug delivery device () is described which comprises a cartridge () containing a plurality of doses of a drug and a piston rod () adapted and arranged to expel drug from the cartridge () during a dose delivery operation of the assembly, the piston rod () comprising a thread (). The assembly further comprises a nut member (), wherein the nut member () is adapted and arranged to be rotated with respect to the piston rod () about a rotational axis () during a dose setting operation of the assembly, the nut member () thereby being axially displaced along the piston rod () from a start position towards an end position with respect to the piston rod () due to mechanical cooperation of the nut member () with the thread (). The assembly further comprises a last dose stop mechanism adapted and arranged to prevent a user from setting a dose of the drug which exceeds a remaining amount of drug in the cartridge (), the last dose stop mechanism comprising at least one first interaction member () and at least one second interaction member () provided by the piston rod () and at least one first stop member () and at least one second stop member () provided by the nut member (), wherein the interaction members () and the stop members () are configured to mechanically cooperate with one another when the nut member () is in the end position with respect to the piston rod () such that further relative movement of the nut member () and the piston rod () for setting a dose of the drug is prevented. Furthermore, a drug delivery device () is described. 11. An assembly for a drug delivery device () comprising:{'b': '4', 'a cartridge () containing a plurality of doses of a drug,'}{'b': 9', '4', '9', '9, 'i': 'a', 'a piston rod () adapted and arranged to expel drug from the cartridge () during a dose delivery operation of the assembly, the piston rod () comprising a thread (),'}{'b': 13', '13', '9', '7', '13', '9', '9', '13', '9, 'i': 'a', 'a nut member (), wherein the nut ...

Cap for a Drug Delivery Device and Drug Delivery Device

A cap for a drug delivery device is provided, the cap comprising a main body and at least one indication element which is moveably retained in the main body, wherein the indication element is configured to be moved from a first position to a second position with respect to the main body, and wherein an information indicated to a user by the cap is changed when the indication element is moved from the first position into the second position. Furthermore, a drug delivery device comprising the previously described cap and an interaction member is provided. 114-. (canceled)15. A cap for a drug delivery device comprisinga main body,at least one indication element which is moveably retained in the main body,wherein the indication element is configured to be moved from a first position to a second position with respect to the main body, and wherein an information indicated to a user by the cap is changed when the indication element is moved from the first position into the second position.16. The cap according to claim 15 , comprising at least one display member configured to display the information to the user.17. The assembly according to claim 15 , wherein the indication element is biased when the indication element is positioned in the first position claim 15 , and wherein claim 15 , when the indication element is in the second position claim 15 , the bias is reduced as compared to the bias in the first position.18. The assembly according to claim 15 , wherein the indication element comprises a locking section claim 15 , wherein the locking section is adapted and arranged such that the indication element is locked in the second position against movement back into first position due to mechanical cooperation of the locking section and the main body.19. The assembly according to claim 18 , wherein the indication element is locked in the second position due to mechanical cooperation of the locking section and the display member.20. The assembly according to claim 19 , ...

Server side macro method, apparatus and computer readable medium

A computer-implemented method of managing computer macros is disclosed. The method includes storing code for a computer macro at an internet-accessible hosted computer system and associating the stored code with a user account on the hosted computer system. The method also includes automatically identifying with the hosted computer system, independent of whether a user associated with the user account is currently active on the hosted computer system, a triggering event that is defined as being directed to the macro. Furthermore, the method includes executing the macro using an application running on the hosted computer system to generate macro results, and storing the macro results on the hosted computer system.

LOCATION-DEPENDENT, SERVER SIDE MACRO METHOD, APPARATUS AND COMPUTER READABLE MEDIUM

A computer-implemented method of managing computer macros is disclosed. The method includes storing code for a computer macro at an internet-accessible hosted computer system and associating the stored code with a user account on the hosted computer system. The method also includes automatically identifying with the hosted computer system, independent of whether a user associated with the user account is currently active on the hosted computer system, a triggering event that is defined as being directed to the macro. Furthermore, the method includes executing the macro using an application running on the hosted computer system to generate macro results, and storing the macro results on the hosted computer system. 1. A computer-implemented method , comprising:storing a computer macro at an internet-accessible hosted computer system;associating the computer macro with a plurality of different user accounts registered with the hosted computer system;receiving location information indicating locations of mobile devices respectively associated with the user accounts; andexecuting the computer macro in response to the location information of at least one mobile device associated with a first one of the user accounts.2. The computer-implemented method according to claim 1 ,said executing step executing the computer macro in response to the location information of a plurality of mobile devices respectively associated with the user accounts.3. The computer-implemented method according to claim 1 , further comprising:tracking an external event external to the hosted computer system to determine occurrence of a triggering event;said executing step executing the computer macro in response to a combination of the location information and occurrence of the triggering event.4. The computer-implemented method according to claim 1 , further comprising:tracking a plurality of external events external to the hosted computer system to determine occurrence of triggering events;said ...

BATTERY HOLDING DEVICE, BATTERY SYSTEM, AIRCRAFT AND METHOD FOR CHANGING A BATTERY FOR AN AIRCRAFT

A battery holding device for an electrically driven aircraft, including a battery holder for accommodating at least one battery, a connection for establishing electrical contact between the at least one battery and an electrical drive of the aircraft, and a primary securing device for locking the at least one battery in the battery holder. The important factor is that the battery holding device includes at least one secondary securing device for locking the at least one battery in the battery holder, wherein the secondary securing device can be closed and released independently of the primary securing device. The invention also relates to a battery system, to an aircraft and to a corresponding method. 1. A battery holding device for an electrically driven aircraft , comprising:a battery holder for accommodating at least one battery;a connection for establishing electrical contact between the at least one battery and an electrical drive of the aircraft;a primary securing device for locking the at least one battery in the battery holder; andat least one secondary securing device for locking the at least one battery in the battery holder, wherein the secondary securing device is closeable and releasable independently of the primary securing device.2. The battery holding device as claimed in claim 1 , wherein the at least one secondary securing device comprises at least one of a mechanical latch claim 1 , a form fit claim 1 , at least one hook claim 1 , or at least one clip.3. The battery holding device as claimed in claim 1 , wherein the at least one secondary securing device is configured such that a connection for establishing electrical contact between the at least one battery and a drive of the aircraft is establishable only in a closed state of the secondary securing device.4. The battery holding device as claimed in claim 1 , wherein the at least one secondary securing device is configured such that the secondary securing device blocks a connection for ...

METHOD FOR PRODUCING PARTICLE FOAMS BASED ON THERMOPLASTIC ELASTOMERS, BY THERMAL BONDING USING MICROWAVES

A method for producing bead foams from foam beads based on thermoplastic elastomers, especially thermoplastic polyurethane, comprises foam beads being wetted with a polar liquid and joined together thermally in a mold via high-frequency electromagnetic radiation, especially microwave radiation, and also the bead foams obtainable therefrom. 1. A method for producing bead foams from foam beads based on thermoplastic elastomers , the method comprising wetting foam beads with a polar liquid and joining the foam beads together thermally in a mold via high-frequency electromagnetic radiation.2. The method according to claim 1 , wherein the foam beads are joined together thermally via microwaves in the frequency range between 100 MHz and 300 GHz.3. The method according to claim 1 , wherein the foam beads comprise a thermoplastic polyurethane.4. The method according to claim 1 , wherein the foam beads have a bulk density in the range from 30 to 250 kg/m.5. The method according to claim 1 , wherein the foam beads are wetted with the polar liquid in proportions of 0.1 to 10 wt % claim 1 , based on the foam beads.6. The method according to claim 1 , wherein the polar liquid has a boiling point in the range from 120° C. to 350° C.7. The method according to claim 1 , wherein the polar liquid comprises (a) esters of carboxylic acids and diols or triols or (b) glycols or liquid polyglycols or mixtures of (a) and (b).8. The method according to claim 1 , wherein the polar liquid comprises glycol esters of acetic or citric acid claim 1 , glycerol esters of acetic or citric acid claim 1 , triethylene glycol claim 1 , tripropylene glycol or mixtures thereof.9. A bead foam obtained by the method of .10. A packaging or footwear claim 9 , comprising the bead foam of . The present invention relates to a method for producing bead foams by joining the foam beads together thermally via high-frequency electromagnetic radiation.Bead foams, such as polypropylene or polystyrene bead foams, ...

Medication Delivery Device

A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pent-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge. 21. The medication delivery device () according to claim 1 , characterized in that{'b': 2', '3', '11, 'when the medication receptacle () is engaged with the distal end of the housing () the reset element () is in the operational state and'}{'b': 2', '3', '11, 'when the medication receptacle () is disengaged from the distal end of the housing () the reset element () is in the resetting state.'}31235454223. The medication delivery device () according to claim 1 , characterized in that the medication receptacle () is designed to be engaged with the distal end of the housing () by engagement of first engagement means () and second engagement means () claim 1 , the first engagement means () and the second engagement means () being moveable into engagement by a movement of the medication receptacle () which comprises a rotational movement without axial movement of the medication receptacle () with respect to the housing ().4127011. The medication delivery device () according to claim 1 , characterized in that the medication receptacle () comprises an actuation means () for bringing the reset element () in the operational state.515427011. The medication delivery device () according to claim 4 , characterized in that the first and second engagement means ( claim 4 , ) are designed such that when the medication receptacle () and the housing are moved into engagement claim 4 , the actuation means are first rotated and moved axially with respect to the housing and are thereafter rotated without being moved axially claim 4 , the actuation means () thereby bringing the reset element () in the operational state.612253334. The medication delivery device () according to claim 3 , ...

METHOD FOR DYEING ELASTOMER PARTICLE FOAMS

The present invention relates to a process for producing colored foamed particles consisting of an elastomer (E), at least comprising the providing of foamed particles made of at least one elastomer (E), and the contacting of the particles with a mixture (MF) comprising a dye (F) and a carrier fluid (TF) to obtain colored foamed particles, wherein the carrier fluid (TF) has a polarity suitable for sorption of the carrier fluid into the elastomer. The present invention further relates to cpspolored foamed particles obtained or obtainable by such a process, and to the use of the colored foamed particles of the invention for production of shaped bodies, especially of footwear soles, parts of a footwear sole, bicycle saddles, cushions, mattresses, underlays, handles, protective films, floor coverings, and components in the automotive interior and exterior sector. 115-. (canceled)16. A process for producing colored foamed particles consisting of an elastomer (E) , the process comprising:(i) providing foamed particles made of at least one elastomer (E),(ii) contacting the particles with a mixture (M) comprising a dye (F) and a carrier fluid (TF) to obtain colored foamed particles,{'sub': 'T', 'wherein the carrier fluid (TF) has a polarity suitable for sorption of the carrier fluid into the elastomer (E), and the carrier fluid (TF) has an E(30) value of not less than 150 kJ/mol.'}17. The process according to claim 16 , wherein the mixture (M) is a solution claim 16 , emulsion or dispersion.18. The process according to claim 16 , wherein the carrier fluid (TF) has a boiling point in the range from 80° C. to 300° C.19. The process according to claim 16 , wherein the carrier fluid (TF) is selected from the group consisting of glycols and of esters of citric acid and glycerol esters.20. The process according to claim 16 , wherein the dye (F) is selected from the group consisting of liquid dyes and solid pigments.21. The process according to claim 16 , wherein the elastomer (E) ...

Medication Delivery Device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device. 11. A medication delivery device () comprising:{'b': '3', 'a housing () having a proximal and a distal end,'}{'b': 2', '3, 'a medication receptacle () designed to be engaged with the housing ()'}{'b': '17', 'a piston rod () which is movable in a distal direction for medication delivery and'}{'b': '17', 'a drive device for rotating the piston rod in a first rotational direction and thereby moving the piston rod () in the distal direction for medication delivery;'}characterized in that{'b': 15', '16', '15', '11', '16', '15', '16, 'the piston rod comprises two threaded sections (, ), wherein a first threaded section () is provided for threaded engagement with a reset element () and a second threaded section () is provided for threaded engagement with the drive device and wherein the threads in the first and second threaded sections (, ) are oppositely disposed,'}wherein{'b': 11', '3', '17, 'in an operational state the reset element () is prevented from rotation with respect to the housing (), the piston rod () thereby being prevented from moving in a proximal direction, and'}{'b': 11', '3', '17', '11', '17, 'in a resetting state the reset element () is allowed to rotate with respect to the housing (), the medication delivery device being resettable by rotating the piston rod () and the reset element () in a second rotational direction and moving the piston rod () in the proximal direction.'}21. The medication delivery device () according to claim 1 , characterized in that{'b': 2', '3', '11, 'when the medication receptacle () is engaged with the distal end of the ...

Microwave welding of elastomer powder

A process for producing moldings from a powder based on thermoplastic elastomers, wherein the powder is placed on a mold or in a mold and by means of electromagnetic radiation is heated to an extent such that the powder undergoes at least partial melting and thus fuses to afford the molding and the frequency of the electromagnetic radiation is between 0.01 GHz and 300 GHz.

Medication Delivery Device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device. 129-. (canceled)30. A dosing apparatus that generates audible and tactile feedback in a medication delivery device , the dosing apparatus comprising:a housing comprising a distal portion and a proximal portion;a piston rod axially moveable in the housing;a rotatable drive sleeve configured to move the piston rod axially during dose dispensing;a dose dial sleeve threadedly engaged to the housing, the dose dial sleeve comprising a dose dial grip disposed about an outer surface of a proximal end of the dose dial sleeve; anda clutch plate coaxially arranged with the dose dial sleeve,wherein rotation of the dose dial sleeve causes a rotation of a first plurality of teeth to ride over a plurality of clutch plate teeth provided on a first surface of the clutch plate,so as to generate audible and tactile feedback when a dose of the medicament is being dialed by rotating the dose dial grip.31. The dosing apparatus ofwherein the first surface of the clutch plate comprises a proximal surface of the clutch plate.32. The dosing apparatus ofwherein the clutch plate moves in a proximal direction during dose dialing.33. The dosing apparatus ofwherein the clutch plate moves in a distal direction during dose dispensing.34. The dosing apparatus of claim 30 , further comprisinga cylindrical threaded insert is fixed to the proximal portion of the housing,wherein the dose dial sleeve is threadedly engaged with a helical rib provided by the cylindrical threaded insert.35. The dosing apparatus of claim 34 , further comprisingat least one radial stop provided along a surface of the ...

Auto-Injector

An auto-injector for delivering a liquid medicament comprising: a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end intended to be applied against an injection site; a plunger unit arranged between the piston and the distal end of the housing, the plunger unit comprising a threaded internal surface for receiving and engaging a threaded rod element; and a tensioned elastic element fixed to the threaded rod element, the elastic element and the threaded rod element being fixed against rotation in an initial state, wherein when the elastic element is rotationally released, the threaded rod element rotates in a first direction, causing the plunger unit to translate towards the proximal end of the housing and thereby pushing the piston towards the proximal end of the housing to displace the medicament. 1. An auto-injector for delivering a liquid medicament comprising:a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end intended to be applied against an injection site;a plunger unit arranged between the piston and the distal end of the housing, the plunger unit comprising a threaded internal surface for receiving and engaging a threaded rod element; anda tensioned elastic element fixed to the threaded rod element, the elastic element and the threaded rod element being fixed against rotation in an initial state,wherein when the elastic element is rotationally released, the threaded rod element rotates in a first direction, causing the plunger unit to translate towards the proximal end of the housing and thereby pushing the piston towards the proximal end of the housing to displace the medicament.2. The auto-injector of claim 1 , wherein the elastic element is a spiral spring coiled around the threaded rod element.3. The auto-injector of claim 1 , further ...

An injection device

An injection device comprising: a housing arranged to contain a liquid medicament or a medicament cartridge; an electrical coil arranged around an inner surface or an outer surface of the housing; an electricity storage apparatus electrically connected to the electrical coil; and a magnet arranged to be movable axially within a defined space with respect to the electrical coil, such that electrical voltage is induced in the electrical coil and a current is generated to charge the electricity storage apparatus.

Cap for an injection device

The present disclosure relates to a cap for an injection device. The injection device comprises a body for holding a syringe having a needle extending from an end thereof. The cap is removably attachable to the body. The cap comprises an actuator and a needle shield to cover said needle. The cap further comprises a coupling between the actuator and the needle shield. The coupling is configured such that when the cap is attached to the body of an injection device axial movement of the actuator away from the body causes rotation of the needle shield relative to the body.

INJECTION DEVICE

The present disclosure relates to an injection device. The injection device comprises a cap and a body for holding a syringe that has a needle at one end. The cap is removably attached to the body and comprises a needle shield to cover said needle. The injection device further comprises a configuration adapted to increase the gas pressure at an interface of the injection device that is disposed between the body and a portion of the cap to urge the body and said portion of the cap apart. 115-. (canceled)16. An injection device comprising:a body for holding a syringe that has a needle at one end;a cap that is removably attached to the body and that comprises a needle shield to cover the needle; anda pressurization mechanism adapted to increase gas pressure at an interface of the injection device that is disposed between the body and a portion of the cap to urge the body and the portion of the cap apart.17. The injection device according to claim 16 , wherein the interface comprises a chamber configured to be disposed between the body and the portion of the cap when the cap is attached to the body.18. The injection device according to claim 17 , wherein the chamber is configured to be disposed between the syringe and the portion of the cap when the cap is attached to the body and when the syringe is received in the body.19. The injection device according to claim 16 , wherein the needle shield comprises the portion of the cap.20. The injection device according to claim 16 , wherein the pressurization mechanism comprises a compressed gas source configured to be selectively in fluid communication with the interface.21. The injection device according to claim 16 , further comprising a base station that has a housing with a recess to receive the cap.22. The injection device according to claim 21 , wherein the base station comprises a cap collection space configured such that the cap moves into the cap collection space when the cap is received in the recess of the housing ...

Supporting wing structure for an aircraft, and aircraft having such a supporting wing structure

A supporting wing structure for an aircraft, in particular for a load-carrying and/or passenger-carrying aircraft, preferably an aircraft in the form of a vertical take-off and landing multicopter having a plurality of electrically driven rotors which are disposed in a distributed manner. The supporting wing structure has a plurality of struts. A first number of the struts are at least largely disposed in a first direction, while a second number of the struts are at least largely disposed in a second direction, the second direction being oriented orthogonal to the first direction. At least the struts of the second number have an aerodynamic profile in cross section, and/or in the struts are connected to one another at least in pairs between neighboring struts by a connecting structure, preferably from individual connecting segments, and the connecting structure or the connecting segments have an aerodynamic profiling. Furthermore an aircraft is provided equipped with such a supporting wing structure.

AIRCRAFT WITH FOLDING MECHANISM

An aircraft with folding mechanism, the aircraft including a fuselage, optionally a payload and/or landing gear attached to the fuselage, at least two longitudinal beams attached to the fuselage that preferably extend parallel to each other and parallel to a first aircraft axis, with lifting units attached to each of the longitudinal beams. At least one crossbeam is attached to the fuselage, and preferably extending parallel to a second aircraft axis and at right angles with respect to the longitudinal beams, with lifting units attached to the crossbeam. The longitudinal beams are rotatably attached to the fuselage by at least one respective first pivot joint configured for pivoting the longitudinal beams around a respective first pivot axis to a pivoted position. The crossbeam is rotatably attached to the fuselage, preferably by at least one second pivot joint, for pivoting the crossbeam around a second pivot axis to a pivoted position. 111. An aircraft () with folding mechanism , the aircraft () comprising:{'b': '2', 'a fuselage ();'}{'b': 7', '1', '7', '2', '2', '3', '7', '1', '7', '2, 'at least two longitudinal beams (., .) attached to said fuselage (), with a plurality of lifting units () attached to each of said longitudinal beams (., .);'}{'b': 8', '2', '7', '1', '7', '2', '3', '8, 'at least one crossbeam () attached to said fuselage () that extends at an angle with respect to said longitudinal beams (., .), with a plurality of lifting units () attached to said crossbeam ();'}{'b': 7', '1', '7', '2', '2', '7', '1', '7', '2', '7', '1', '7', '2, 'said longitudinal beams (., .) are rotatably attached to said fuselage () by at least one respective first pivot joint configured for pivoting said longitudinal beams (., .) around a respective first pivot axis to a pivoted position (.′, .′); and'}{'b': 8', '2', '8', '8, 'said crossbeam () is rotatably attached to said fuselage () by at least one second pivot joint, configured for pivoting said crossbeam () around a ...

Toothbrush head of an electric toothbrush

The invention relates to a toothbrush head for an electric toothbrush comprising a brush head support, on which a bristle support having a bristle array is displaceably mounted. Engaging means are provided on the fastening section of the brush head support and, when the brush head support is linearly and axially slid onto the handle of the toothbrush, serve to engage with the detent means provided thereon. In order to achieve an efficient cleaning, the invention also provides that a number of groups of bristle bunches are fastened to the motor-driven bristle support. These bristle bunches are slanted in different directions and have different cross-sections, preferably also non-circular cross-sections, in order be able to penetrate better inside interdental spaces and to effectively remove plaque. A stationary bristle support is preferably fastened to the toothbrush head next to the moving bristle support, whereby a number of bristle bundles are fastened to the stationary bristle support. These bristle bundles are likewise slanted in different directions and preferably have different cross-sections.

WATER VAPOR-PERMEABLE COMPOSITE MATERIAL

A composite material contains a nonwoven layer (i) which contains fibers formed from a first thermoplastic elastomer having meshes with a mesh size in the range from 10 to 100 μm, and a membrane layer (ii) which contains a second thermoplastic elastomer and having a layer thickness of less than 30 μm. The membrane is either pore-free (ii.1) or is porous and has pores with an average pore diameter of less than 2000 nm (ii.2). The membrane (ii) is at least partially in direct contact with the fibers of the nonwoven layer (i) and covers the mesh openings in the nonwoven layer (i) at least partially. The fibers of the first nonwoven layer (i) and the membrane (ii) in the contact area are at least partly joined to one another in an interlocking manner. 114-. (canceled)15: A process for producing a composite material , comprising:a) providing a nonwoven layer (i) comprising fibers formed from a first thermoplastic polyurethane and having meshes with a mesh size in the range from 10 to 100 μm, determined by scanning electron microscopy;b) providing a membrane layer (ii) comprising a second thermoplastic polyurethane which is compatible with the first thermoplastic polyurethane of the nonwoven layer (i), wherein the membrane layer is porous and has pores with an average pore diameter of less than 2000 nm, determined by Hg porosimetry in accordance with DIN 66133, (ii.2);c) applying the membrane layer (ii) to the nonwoven layer (i) and joining (i) and (ii) in an interlocking manner by cold welding;to obtain a composite material;whereincold welding according to (c) means that the fibers of the nonwoven layer (i) and the membrane (ii) in the contact area at least partly form an interlocking join with one another, wherein on account of the presence of solvent firstly the nonwoven layer (i) and/or the membrane layer (ii) partly dissolve, and then the membrane layer (ii) hardens on the nonwoven layer (i) when the solvent is removed.16: The process for producing a composite ...

Toothbrush head of an electric toothbrush

The invention relates to a toothbrush head for an electric toothbrush comprising a brush head support, on which a bristle support having a bristle array is displaceably mounted. Engaging means are provided on the fastening section of the brush head support and, when the brush head support is linearly and axially slid onto the handle of the toothbrush, serve to engage with the detent means provided thereon. In order to achieve an efficient cleaning, the invention also provides that a number of groups of bristle bunches are fastened to the motor-driven bristle support. These bristle bunches are slanted in different directions and have different cross-sections, preferably also non-circular cross-sections, in order be able to penetrate better inside interdental spaces and to effectively remove plaque. A stationary bristle support is preferably fastened to the toothbrush head next to the moving bristle support, whereby a number of bristle bundles are fastened to the stationary bristle support. These bristle bundles are likewise slanted in different directions and preferably have different cross-sections.

Toothbrush head of an electric toothbrush

Die vorliegende Erfindung betrifft einen Zahnbürstenkopf für eine elektrische Zahnbürste mit einem Bürstenkopfträger, an dem ein Borstenträger mit einem Borstenfeld beweglich gelagert ist. Es ist vorgesehen, dass am Befestigungsabschnitt des Bürstenkopfträgers Verrastmittel vorgesehen sind, die bei geradlingem, axialem Aufschieben des Bürstenkopfträgers auf das Handteil der Zahnbürste mit den daran vorgesehenen Rastmitteln verrasten. Um ein effizienteres Putzen zu erreichen, ist ferner vorgesehen, dass an dem motorisch antreibbaren Borstenträger mehrere Gruppen von Borstenbüschel befestigt sind, die in verschiedenen Richtungen geneigt angeordnet sind und verschiedene Querschnitte, vorzugsweise auch von der Kreisform abweichende Querschnitte, besitzen, um besser in Zahnzwischenräume eindringen zu können und Plaque effektiv zu beseitigen. Vorzugsweise ist neben dem beweglichen Borstenträger ein unbeweglicher Borstenträger am Zahnbürstenkopf befestigt, wobei an dem unbeweglichen Borstenträger mehrere Gruppe von Borstenbüschel befestigt sind, die in verschiedene Richtungen geneigt angeordnet sind und vorzugsweise unterschiedliche Querschnitte besitzen. The present invention relates to a toothbrush head for an electric toothbrush with a brush head carrier on which a bristle carrier with a bristle field is movably mounted. It is provided that latching means are provided on the fastening section of the brush head carrier, which latch when the brush head carrier is slid axially onto the hand part of the toothbrush with the latching means provided thereon. In order to achieve more efficient cleaning, it is further provided that several groups of bristle tufts are attached to the motor-driven bristle carrier, which are arranged inclined in different directions and have different cross sections, preferably also cross sections deviating from the circular shape, in order to better penetrate between the teeth to be able to effectively remove plaque. In addition to the movable ...

Method for manufacturing a composite work piece for a drug delivery device and composite work piece for a drug delivery device

Method for manufacturing a composite work piece for a drug delivery device, comprising the steps: Providing a first work piece part 1 and a second work piece part 2, arranging both work piece parts 1, 2 with respect to each other in such a way that both work piece parts 1, 2 are in mechanical contact with one another in a contact area 3, irradiating a surface of the first work piece part 1 with electromagnetic radiation, thereby softening the first work piece part 1 and/or the second work piece part 2 in a region adjacent to the contact area 3, and joining the first work piece part 1 to the second work piece part 2 in the contact area 3 for the composite work piece. Furthermore, a composite work piece for a drug delivery device is provided.

Electric shaver

The proposed electric shaver (3) has at least one electric motor in a housing (1, 2), at least one stubble-cutting system (K1, K2), a movable trimmer (L1) and an operating switch (9). The trimmer (L1) can be switched by an electric motor-driven transmission unit to and from at least one operating position.

Electric shaver

The proposed electric shaver (3) has at least one electric motor in a housing (1, 2), at least one stubble-cutting system (K1, K2), a movable trimmer (L1) and an operating switch (9). The trimmer (L1) can be switched by an electric motor-driven transmission unit to and from at least one operating position.

Medication delivery device

The present invention relates to a medication delivery device, to dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having dose setting means and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge, to a use of such device, and to a method of manufacturing or assembling such device.

Drug delivery device and method of manufacturing a drug delivery device

Drug delivery device

Mounting arrangement and coupling assembly for a drug-delivery device

A mounting arrangement for a drug-delivery device is proposed, the mounting arrangement comprising: a plug element (2) with a longitudinal axis (L) and a housing part (8) having a recess (10) with a side wall (12) which is adapted to receive the plug element (2). At least one of the plug element (2) or the side wall (12) of the recess are provided with a protrusion (16) for fixing the plug element (2) in a given position relative to the housing part (8) by a force-fit engagement. Furthermore, a coupling assembly is proposed, the coupling assembly comprising the plug element (2) and the housing part (8) being mechanically coupled to each other.

Method for manufacturing a drug delivery device body using an adhesive and drug delivery device body

The invention relates to a method for manufacturing a drug delivery device body comprising the following steps: At first a first part (1) of the drug delivery device body wherein the surface of the first part of the drug delivery device body consists of at least one selected area (5) and at least one non selected area (6) is provided. The selected area (5) of the drug delivery device body is a part of the contact area of the first part (1) and a second part (2) of the drug delivery device body to be fixed to the first part (1) of the drug delivery device body. Subsequently a layer of an adhesive (3) is deposited on the surface of the first part (1); means for deposition of the adhesive only in the selected area are provided. The first part (1) with the layer of adhesive (3) and the second part (2) are joined so that the layer of the adhesive (3) is only arranged in the contact area of the first and the second part (1, 2) of the drug delivery device body.