УМЕНЬШЕНИЕ ОБЪЕМА ТКАНИ

Изобретение относится к медицине, а именно к пульмонологии, и может быть использовано при заболеваниях легких, требующих уменьшения объема поврежденной ткани легкого или герметизации его в случае спонтанного пневмоторакса. Для этого через бронхоскоп, подведенный к участку-мишени, по катетеру вводят определенный материал. Количество и природа материала должны быть достаточными для стимуляции адгезии между одной спавшейся частью участка-мишени легкого и другой и фиброза участка-мишени легкого или вокруг участка-мишени легкого, в котором произошел коллапс. Данный материал на основе фармацевтических композиций содержит в своем составе полипептидный фактор роста, компонент внеклеточного матрикса, вазоактивное вещество, про-апоптотический агент. При этом композиции дополнительно включают фибриноген или мономер фибрина, или активатор фибриногена. Изобретение позволяет достичь направленной стимуляции адгезии участка-мишени, фиброза самого участка-мишени или вокруг участка, в котором возник коллапс ...

ВНУТРИСОСУДИСТЫЕ ОККЛЮЗИОННЫЕ УСТРОЙСТВА ДЛЯ НАПРАВЛЕНИЯ ПО ЧРЕСКОЖНОМУ КАТЕТЕРУ

Изобретение относится к медицине и может быть использовано для создания окклюзии аномального отверстия в органе тела или сосуде. Плетеная металлическая структура обладает свойством памяти, в силу которого медицинское устройство стремится вернуться в упомянутую расширенную предварительно заданную конфигурацию, когда находится в свободном состоянии. Устройство дополнительно содержит, по меньшей мере, один дискообразный участок, расположенный рядом с корпусным цилиндрическим участком, сформированным из структуры, и имеет переходный диаметр между дискообразным и цилиндрическим участками, который значительно меньше, чем диаметр дискообразного и диаметр цилиндрического участков. В результате усовершенствованное окклюзионное устройство обеспечивает повышенную гибкость между диском и цилиндрическим диаметром для улучшения совмещения диска со стенкой отверстия, имеет повышенную удерживающую способность. 3 н. и 17 з.п. ф-лы, 10 ил., 1 табл.

УСТРОЙСТВА, СИСТЕМЫ И СПОСОБЫ ОККЛЮЗИИ СОСУДОВ И ПОДАЧИ ЛЕКАРСТВЕННЫХ СРЕДСТВ

... 1. Окклюдирующее устройство, содержащее:биопоглощаемый, окклюдирующий просвет имплантат, пропитанный терапевтическим средством, причем биопоглощаемый, окклюдирующий просвет имплантат имеет одну из следующих форм: эллипсоидную, овоидную, сферическую или цилиндрическую; иприсоединенное к нему биопоглощаемое средство прикрепления, причем средство прикрепления содержит один элемент из шовной нити и зубца.2. Окклюдирующее устройство по п. 1, в котором терапевтическое средство является склерозирующим средством.3. Заранее загруженная капсула, содержащая:корпус, образующий камеру подачи и имеющий входной и выходной концы; и биопоглощаемый, окклюдирующий просвет имплантат с присоединенным к нему биопоглощаемым средством прикрепления,при этом биопоглощаемый, окклюдирующий просвет имплантат расположен внутри камеры подачи и пропитан терапевтическим средством.4. Капсула по п. 3, в которой корпус содержит первый суженый переходник вокруг входного конца и второй суженый переходник вокруг выходного конца ...

УСТРОЙСТВО И СИСТЕМА ОГРАНИЧЕНИЯ ПОТОКА ЖИДКОСТИ В ФИЗИОЛОГИЧЕСКИХ СОСУДАХ

УСТРОЙСТВО ДЛЯ РЕКОНСТРУКЦИИ СОСУДОВ

... 1. По существу, сферическое реконструкционное устройство, содержащее ! первый конец, ! второй конец, по существу, противоположный первому концу, и ! волокна, проходящие между первым концом и вторым концом и соединенные с первым концом и вторым концом, и выполненное с ! возможностью постоянного размещения в месте соединения нейрососудистой бифуркации, содержащей по меньшей мере один афферентный сосуд, эфферентные сосуды и аневризму, имеющую шейку, ! возможностью осуществления функции системы опор с предотвращением грыжеобразования объектов наружу шейки аневризмы и ! возможностью обеспечения перфузии жидкости к эфферентным сосудам. ! 2. Устройство по п.1, которое выполнено в целом в форме футбольного мяча и в котором первый конец и второй конец проходят наружу. ! 3. Устройство по п.1, которое выполнено в целом в форме тыквы и в котором первый конец и второй конец проходят внутрь. ! 4. Устройство по любому из пп.1-3, в котором волокна содержат обладающий памятью формы материал. ! 5. Устройство ...

ПЛЕТЕНОЕ ОККЛЮЗИОННОЕ УСТРОЙСТВО С ПОВТОРЯЮЩИМИСЯ РАСШИРЕННЫМИ ОБЪЕМНЫМИ СЕГМЕНТАМИ, РАЗДЕЛЕННЫМИ СОЧЛЕНЯЮЩИМИ СЕГМЕНТАМИ

... 1. Устройство (100) окклюдера для окклюдирования целевого участка, содержащее:трубчатую структуру с проксимальным и дистальным концами и заранее установленной расширенной конфигурацией, причем трубчатая структура имеет отношение длины к максимальному наружному диаметру по меньшей мере примерно 4 в заранее установленной расширенной конфигурации, при этом трубчатая структура конфигурирована для сжатия до уменьшенной конфигурации для подачи на целевой участок и по меньшей мере частичного возврата к заранее установленной расширенной конфигурации внутри целевого участка, когда она не сжата, причем заранее установленная расширенная конфигурация включает множество расширенных объемных элементов (102) и сочленяющих элементов (104), расположенных повторяющимся образом, где множество расширенных элементов включает по меньшей мере один элемент в форме сферы или овалоида, с каждым сочленяющим элементом, соединяющим пару расширенных объемных элементов, и каждый расширенный объемный элемент имеет размер ...

Окклюзирующее устройство

Ballonkatheter zum Verschliessen von Aneurysmen oder Nebenblutgefässen

Gerät zur Positionierung einer Emboliespule

SPIRALE ZUR OKKLUSION VON BLUTGEFAESSEN MIT EINER GEWEBTEN SCHLAUCHFOERMIGEN FASERUMHUELLING

Stripper aid for helical implants on guide wire - has stop ring at guide tube front end, and wire distal end coupler connected to second slide sleeve

A stripper surrounds the guide wire, and there is a guide tube (4), whose front end contains a cap (5) with a bore for the passage of the stripper and guide wire. On the guide tube is fitted a slide sleeve (7) with a coupler for the wire distal end forming a nipple. A stop ring and the stripper distal end coupler complete the design. The stop ring is at the front end of the guide tube, and the second coupler is connected to a second slide sleeve between the stop ring and the first slide sleeve. The couplers for the guide wire and stripper respectively are fitted in the guide tube, while the slide sleeves surround the guide tube. USE/ADVANTAGE - For vessel closing helical implants in interventional radiology, with independent motion of stripper and guide wire.

TRANSCERVIKALE VERHÜTUNGSVORRICHTUNG ZUM EILEITERVERSCHLIESSEN MIT MECHANISCHER BEFESTIGUNG AM EILEITER

OCCLUSIONSINSTRUMENT UND VERFAHREN ZU DESSEN HERSTELLUNG

Verschlussvorrichtung

VASKULÄRE VORRICHTUNG ZUM ZUSAMMENBRINGEN VON VENTILKLAPPEN

Vorrichtung zum Verschließen einer Öffnung, beispielsweise in einer Wand eines hohlen oder röhrenförmigen Organs

Gerät zur Bildung eines Embolus in einem Aneurysma

Vorrichtung zur intravaskulären embolisierung

VORRICHTUNG ZUR IMPLANTATION VON MIKROWENDELN

VORRICHTUNG ZUM ABDICHTEN EINER ÖFFNUNG IN EINEM HOHLEN ODER ROHRFÖRMIGEN ORGAN

VORRICHTUNG ZUR IMPLANTATION VON FILAMENTEN IN DEN KÖRPER

Embolusfangvorrichtung und Anordnung zum Anbringen desselben

System zur Behandlung von Aneurysmen

Vorrichtung zum Verschließen einer Verbindung zwischen der Aorta und der Arteria pulmonalis

Vorrichtung (1) zum Verschließen einer nach der Geburt offen gebliebenen Verbindung (2) zwischen der Aorta (3) und der Arteria pulmonalis (4) mit einem in diese Verbindung mittels Katheter (7) einführbaren Verschlusselement, wobei das Verschlusselement (8) zwei beabstandete, über ein Zugelement (9) elastisch verbundene Verschlüsse (10, 11) aufweist, die in Gebrauchsstellung die beiden Mündungen der zwischen der Aorta (3) und der Arteria pulmonalis (4) befindlichen Verbindung (2) abdecken oder ausfüllen, dadurch gekennzeichnet, dass ein Verschluss (11) und das Zugelement (9) eine durchgehende, bis in die Nähe des anderen Verschlusses (10) reichende Innenlängshöhlung (12) für den Eintritt eines Mandrins oder eines Schiebe- und/oder Drehwerkzeuges hat, die an ihrem Ende ausgesteift und armiert ist, und dass im Bereich des Eintrittes in die Innenlängshöhlung (12) des Zugelementes (9) eine Armierung angeordnet ist, an welcher eine über den unmittelbar benachbarten Verschluss (11) nach außen ...

Aneurysm closure device

A vascular flow diverter 50, suitable for diverting flow from an aneurysm at a vessel bifurcation, includes a frame member 52 formed of crossing frame struts/elements 70, 72 and a diverter element 60 formed of a plurality of resiliently deformable blade elements 62 extending in radially opposing directions from a support element 58 of the frame. The frame member has first and second ends, the support element being situated at the first end and the frame struts/elements extending from the first to the second end. The blade elements may curve in a direction away from the frame member and may be concave when viewed in a direction from the first end to the second end of the frame member.

Implantable medical device with twisted element

Apparatus for use in coronary artery bypass surgery

The apparatus comprises a blood flow conduit 10 of T- or L-shape having a first end for insertion into and retention within a wall of a heart chamber 44 containing oxygenated blood and a second end for retention within a coronary artery 30, the conduit defining an open flow blood path during both systole and diastole. The conduit may be such as to bias forward flow of blood from the first towards the second end while not blocking reverse flow and may comprise a deflection surface for blocking flow through the conduit from impinging directly upon the coronary artery. Means may be provided in the conduit for reducing but not blocking blood flow during diastole.

Device for fixation of a sensor in a bodily lumen

Implantable graft assembly and aneurysm treatment

Implantable medical device with flexible connection

An implantable double-ended medical device 10 such as a filter or occluder has first and second conical material capture filter baskets 12, 14 disposed in opposing orientations with their narrow ends 18 facing one another in an hourglass arrangement and connected by a flexible connector 26, which enables the implantable medical device 10 to curve within a curved vessel of a patient. The flexible connector 26 may be a coiled wire, helically cut cannula, made from a flexible material, formed by a flexible rod with transverse grooves, channels or recesses or be integral with shape memory alloy or spring steel framework of the material capture baskets - and is either closed or has a lumen passing therethrough with a closure element such as valve or incorporating thrombogenic fibres for closing the lumen after deployment of the device 10 within a patient.

Cone Expanding Collapsible Medical Device

A collapsible medical device 10 includes two conical members 20, with tooth shaped wide ends 40, coupled to one another by a connector 52, which may be a cannula or rod. The conical members 20 are formed of a membrane 22 which has a thickness which decreases from a narrow end 24 to a wide end 26. The membrane 22 may be self-supporting and may be formed of silicone. There may be a frame (70 fig 5) coupled to the conical members 20 which may be made of a shape memory alloy such as Nitinol and may be embedded within the membrane 22. The teeth 40 may be self-supporting within a vessel and avoid folds within the membrane 22, which may otherwise result in leakage of blood around the device 10. The device may be a vascular occluder or a filter.

Medical device loading and carrier tool

Vascular plug

Vascular Occluder with Crossing Frame Elements

Vascular occluder

Device and method for internal ligation of tubular structures

A surgical device for performing internal ligation of a fallopian tube (31) or other tubular anatomical structure, by application of one ore more ligating bands (41) to a folded portion of the wall of the tubular structure. A method of using the device is a!*0 disclosed. The invention method and device may be used for sterilization to prevent undesired pregnancies, or for other medical applications. One embodiment of the device includes an elongated tubular element (21) that is inserted into the fallopian tube, a grasper (51) that extends out of the tubular element (21), grasps the interior of the fallopian tube (31) and retracts into the tubular element in a folded bundle of the fallopian tube tissue; and a pusher balloon (42) for pushing a ligating band (41) from the tip of the tubular element into the tissue bundle. A fold assist mechanism may be included to help evert a section of a fallopian, or other, tube.

Therapeutic foam.

Device and method for interbal ligation of tubularstructures

DIVERSON DEVICE FOR THE INCREASE OF THE BRAIN BLOOD CIRCULATION

CATCH COIL

IMPLANTIERBARE VASCULAR DEVICE

DEVICE TO VASKULAREN EMBOLISATION

SYSTEM IN TO EMBOLIESPIRALE WOULD BRING

REMOVABLE INTRODUCTION ASSISTANCE FOR A SYSTEM FOR BRINGING IN A MEDICAL INSTRUMENT

IMPLANT FOR THE OKKLUSION OF A BODY CHANNEL

TRANSCERVIKALE PREVENTING DEVICE TO THE EXPRESS PUS CATCH WITH MECHANICAL ATTACHMENT AT THE EILEITER

DEVICE FOR THE INTRODUCTION OF A DEVICE TO INTRAVASKULÄREN EMBOLISIERUNG

SOLVABLE DEVICE WITH ELECTRICALLY REACTIVE ELEMENT

EMBOLISIERUNGSVORRICHTUNG A-TOTALLY ENCLOSED IN FOAM STENCIL

FLEXIBLE EMBOLIE DEVICE ABGABESYSTEM ONE

RAPAMYCIN CONTAINING MEDICAL DEVICES

VERSCHLUSSVORRICHTUNG FOR SURGICAL OR MEDICAL PURPOSES

IMPLANT FOR LOCKING A KÍRPERÍFFNUNG

EMBOLUSFANGVORRICHTUNG AND ARRANGEMENT FOR THE ATTACHMENT OF THE SAME

VERSCHLUSSVORRICHTUNG FOR A BODY TUBE, IN PARTICULAR OF CRAMP VEINS

DEVICE FOR THE PREVENTION OF NOT DESIRED FLOW OF THE EMBOLIS OF THE VENEN INTO THE ARTERIEN

EINBRINGUNGSUND DEVELOPMENT CATHETER SYSTEM FOR EILEITERKONTRAZEPTIONSMITTEL

Method for intermittent occlusion of coronary sinus in heart of patient, involves releasing occlusion of coronary sinus as function of one characteristic value derived from pressure values in occluded coronary sinus

The method involves occluding coronary sinus of patient using occlusion device coupled to distal end (2) of multi-lumen catheter (1). The occlusion device is adjusted between non-occluding state and occluding state to occlude coronary sinus. The fluid pressure values of occluded coronary sinus are measured and stored during occluding process. The pulsating pressure is output into coronary sinus from pulsating membrane structure. The occlusion of coronary sinus is released as function of one characteristic value derived from pressure values in occluded coronary sinus.

TRANSZERVIKAL APPLICABLE ONES EMPFÄNGNISVERHÜTUNGSVORRICHTUNG FOR THE CATCH OF THE EILEITER WITH MECHANICAL ATTACHMENT AT THE EILEITER AND INTRODUCTION SYSTEM

PROCEDURE FOR THE PRODUCTION OF A FOAM WITH A SKLEROSIERENDEN MEANS

PROCEDURE FOR THE PRODUCTION OF MEDICAL DEVICES; INTRAVASKULÄROKKLUSIONSVORRICHTUNG

VERSCHLUSSVORRICHTUNG FOR SURGICAL OR MEDICAL PURPOSES

EXPAND-CASH DEVICE FOR APPLICATION IN BLOODSTREAMS IS USED AND TENSION APPLIKATOR HERE

WITH BIOLOGICAL ONES OR BIOLOGICAL DEGRADABLE ONES OR SYNTHETIC POLYMERS OR FIBERS UMSCHLUNGENE METAL COILS TO EMBOLISIERUNG THE BODY CAVITY

OCCLUSIONSINSTRUMENT FOR LOCKING A HERZOHRES

DEVICE FOR THE INTERMITTENT OKKLUSION OF THE CORONARY SINE

System for intermittent occlusion of especially coronary veins with pulsating pressure and with blood pressure monitoring

A system for intermittent occlusion, especially for coronary veins, includes a pulsating pressure applied to the occluding element while the variation with time of the blood pressure is monitored. The pressure management encourages retro-infusion of blood and the pulsation is typically between 100 and 200 beats per minute. The pulsation can be applied pneumatically or hydraulically using membranes, balloons, piezo elements etc.

HYDRAULIC RELEASE SYSTEM FOR EMBOLIESPIRALFEDERN WITH SMALL DIAMETER

INSTRUMENTARIUM ZUM NICHT-CHIRURGISCHEN VERSCHLIESSEN EINES EILEITERS

PROCEDURE FOR THE PRODUCTION OF A OKKLUSIONSVORRICHTUNG

VASKULARE SAFETY DIVICE FOR BLOOD

OKKLUSIONSVORRICHTUNG TO THE ANASTOMOSIS

COIL WITH MULTIPLE STRANDS FOR THE INTERVENTIONELLE THERAPY

FAST EXCHANGEABLE CATHETER

EQUIPMENT FOR NON--SURGICAL LOCKING OF A EILEITERS

ENTRANCE OPENING WITH KLIP AND USE PROCEDURE

GEF�SSFILTERSYSTEM

PIEZOELECTRIC DEVICE FOR THE DELIVERY OF A VASCULAR IMPLANT

DEVICE TO EMBOLISATION A ANEURISMUS WITH CATCH ARRANGEMENT

WITH A MECHANICAL RELEASING MECHANISM PROVIDED EINFÜHRVORRICHTUNG FOR A EXPANSION-RESISTANT EMBOLIESPIRALE

MEDICAL IMPLANT

PARTIAL ONE AORTENOKKLUSIONSVORRICHTUNG FOR THE INCREASE THE ZELEBRALEN BLOOD CIRCULATION

PROCEDURE FOR THE PRODUCTION OF EXPAND-CASH FILAMENT EYES EMBOLISIERUNGSVORRICHTUNGEN

DEVICE FOR THE INTERMITTENT OKKLUSION OF THE CORONARY SINE

DEVICE FOR LOCKING A CONTAINER DEFECT

INTRAVENOUS DEVICE TO THE COMPLETE ONE OR PARTIAL ONE FLATTENING A VENE.

DEVICE FOR THE ANALYSIS OF THE DEGREE OF THE FABRIC DAMAGE IN A HEART THE INSUFFICIENT ARTERIAL ONE BLUTSTRÖMUNG SUSPENDED.

INTERMITTENT CATCH OF THE CORONAR SINE WITH PRINTING PRESSURE.

EMBOLIESPIRALE WITH DEVIATING AXLES AND ROTATION FORMS

DEVICE FOR THE INTERRUPTION OF THE FLOW OF TEARS

ELECTROLYTICALLY SEPARABLE SPIRAL WITH MOBILE POINT OF REPLACEMENT

ARRANGEMENT OF A SOLVABLE EMBOLIESPIRALFEDER

ENDOVASKULÄRE ELECTROLYTIC SEPARABLE ONE GUIDANCE WIRE POINT

EXPAND-CASH IMPLANT TO THE VASCULAR ONE EMBOLISATION, AS WELL AS PROCEDURES FOR ITS PRODUCTION

CATHETER WITH IMPORTABLE THROMBOGENER DRAHTWICKLUNG

DEVICE FOR THE TREATMENT OF THE GASTRO-INTESTINAL TRACT AND KIT FOR IT

MORE ENDOVASKULÄRER, ELECTROLYTIC SEPARABLE WIRE FOR THE FORMATION OF THROMBEN

ENDOVASKULÄRE DEVICE TO EMBOLISIERUNG AN ANEURYSM

DEVICE FOR THE IMPLANTATION OF OCCLUSIONSWENDELN

EMPFÄNGNISVERHÜTUNGSSYSTEM

Device for the implantation of occlusion spirals

A device for the implantation of electrolytically severable occluding spirals in body cavities or blood vessels comprising a source of electrical power, a cathode, a catheter and an occluding spiral adapted to serve as an anode and able to slide in the catheter in the longitudinal direction, wherein the occluding spiral ( 3 ) is designed to be electrolytically corrodible at several spaced apart points so that when in contact with a body fluid one or more variably dimensioned lengths of the occluding spiral ( 3 ) may be severed by electrolysis.

Method and apparatus for recapturing an implant from the left atrial appendage

A system and method for retrieving an implantable device includes a delivery catheter, a recapture section, and a sheath. The delivery catheter has a proximal end and a distal end. The recapture section is axially extendable from the distal end of the delivery catheter. The sheath has a proximal end and a distal end and a lumen sized to receive the delivery catheter. A portion of the lumen of the sheath is actuatable from an enlarged inside diameter to a reduced inside diameter to apply an inwardly directed force to the recapture section. The delivery catheter can be actuated with respect to the sheath to extend or retract the recapture section with respect to the delivery catheter.

Apparatus and methods for occluding an anatomical structure

Apparatus and methods are disclosed for occluding an anatomical structure including an occlusion apparatus having first and second beams and at least one connector for connecting the respective ends of the beams together. The occlusion apparatus may be adapted for use in a deployment device having a pair of jaws and optionally having a respective pair of shuttle bodies for releasably connecting an occlusion apparatus to the jaws while in an open position and for releasing the occlusion device from the jaws while in a closed position. A system for occluding an anatomical structure is also disclosed that includes an occlusion apparatus and a deployment device for holding the occlusion apparatus in an open position for locating the occlusion device adjacent the anatomical structure to be occluded and then moving the occlusion apparatus to a closed position and locking the occlusion apparatus in the closed position.

Methods and Devices for Conduit Occlusion

The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of elements for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable or degradable material that supports tissue ingrowth or wound healing or a similar response that replaces the cured occlusive material leaving little or no original occlusive material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.

Occlusion devices and methods

The invention provides intrafallopian devices and non-surgical methods for their placement to prevent conception. The efficacy of the device is enhanced by forming the structure at least in part from copper or copper alloy. The device is anchored within the fallopian tube by a lumen-traversing region of the resilient structure which has helical outer surface, together with a portion of the resilient structure which is biased to form a bent secondary shape, the secondary shape having a larger cross-section than the fallopian tube. The resilient structure is restrained in a straight configuration and transcervically inserted within the fallopian tube, where it is released. Optionally, permanent sterilization s effected by passing a current through there resilisent structure to the tubal walls.

Self-expanding pseudo-braided intravascular device

A self-expanding, pseudo-braided device embodying a high expansion ratio and flexibility as well as comformability and improved radial force. The pseudo-braided device is particularly suited for advancement through and deployment within highly tortuous and very distal vasculature. Various forms of the pseudo-braided device are adapted for the repair of aneurysms and stenoses as well as for use in thrombectomies and embolic protection therapy.

Surgical Implant

A surgical implant comprises a body having a compressed state and an uncompressed state. An envelope contains the body in at least the compressed state. The envelope forms an air-tight seal around the body in the compressed state and is water-soluble or degradable in body fluids.

Occlusion device

A vascular occlusion device for occluding a body cavity includes an elongate member for injecting embolization material into the body cavity and a deflecting device. The deflecting device is disposed around a distal end of the elongate member and is expandable to contact an interior wall of the body cavity in the expanded state. The deflecting device is configured to be deflected by the embolization material to change a shape of the deflecting device in the expanded state. The deflecting device provides a visual and tactile indication of completion of embolization based on the shape of the deflecting device in the expanded state.

Embolization coil

An embolic coil configured in such a manner that the risk that a stretch preventing wire breaks is very small even if the embolic coil is wound to a diameter smaller than the diameter of a secondary shape of the coil imparted thereto and also in such a manner that the embolic coil has excellent deliverability. An embolic coil is configured in such a manner that a stretch preventing wire and a coil, a part or the whole of said coil being coarsely wound, are affixed to each other at at least two different points. The portion of the stretch preventing wire which is located between the two different portions is provided with a portion to which a stretchable shape has been imparted.

Self-expanding occlusion device

An occlusion device for implantation within a body lumen includes a distal end, a proximal end, and an expandable member extending from the distal end to the proximal end. The expandable tubular member defines a passageway extending from the distal end to the proximal end. The expandable tubular member includes a plurality of struts that are joined to adjacent struts to form a plurality of closed shapes each defining a closed path. The plurality of struts are joined to form a plurality of fixed joints so that adjacent struts are pivotable around respective one of the fixed joints when an external force is applied to the expandable tubular member. The tubular member defines an ellipsoid shape.

Stretch resistant therapeutic device

A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.

Expandable implant devices for filtering blood flow from atrial appendages

Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

Detachable aneurysm neck bridge

In one embodiment, a neck bridge for bridging the neck of an aneurysm includes a junction region, a number of radially extending array elements attached to the junction region, and a cover attached to one or both of the junction region and an array element. The array elements are configured to be positioned within the aneurysm after the neck bridge is deployed from a delivery device. In a second embodiment, the neck bridge includes a junction region and a braided or mesh-like structure secured to the junction region. The braided or mesh-like structure is made from an elastic material.

Devices and methods for treatment of vascular aneurysms

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Multi-fiber shape memory device

A shape memory coiling device ( 5 ) for occluding a vessel or other vascular target includes a shape memory polymer material. The shape memory material is formed in a formation state as a plurality of coiled members ( 10 ) and then constrained in a pre-deployed state as a plurality of elongate members ( 10 ) configured for delivery through a delivery device wherein the plurality of elongate members ( 10 ) are aligned axially with respect to each other and the delivery device ( 20 ). The shape memory material may be formed in an intra-deployed state such that at least one of the plurality of elongate members ( 10 ) will anchor the device ( 5 ) before filling the vascular target and becoming a coiled member. The shape memory material is formed in a deployed state as a plurality of coiled members ( 10 ). In some embodiments, the vascular target is an aneurysm.

Biopolymer microthreads with microscale surface topographies

In one aspect, the invention features a textured microthread that includes or is fashioned from a naturally occurring polymer and that has a surface comprising micron-scale ridges with intervening grooves.

Double bellow occluder for sclerotherapy

The disclosed subject matter describes systems and methods of delivering a therapeutic agent, such as a sclerosing agent, to the walls of a blood vessel to perform sclerotherapy. In an exemplary embodiment a catheter includes a guidewire catheter having at least one guidewire lumen extending therethrough and a slidable concentric tube disposed over the guidewire catheter. At least one bellow is coupled to the concentric tube and configured for conversion between an unexpanded and expanded configuration wherein movement of the concentric tube in a first direction causes the at least one bellow to expand and movement of the concentric tube in a second direction causes the at least one bellow to contract. Additionally, the concentric tube contains at least one port for delivery of a therapeutic agent, e.g. a sclerosing agent. The at least one bellow expands and contracts via mechanical forces.

Occlusion Device

An occlusion device (e.g., for treatment of the left atrial appendage) includes a framework and a biocompatible covering disposed over at least a part of the framework. The framework may include a proximal portion, a middle portion, and a distal portion, wherein: the proximal portion includes a first hub that has a fixed first diameter; the middle portion has a second diameter and includes a plurality of beams extending from the first hub to a distal portion, wherein each of the plurality of beams is connected to an adjacent beam by a first circumferentially extending column of strut pairs; and the distal portion has a third diameter. In one or more embodiments, the framework includes improved circumferential strength and minimizes foreshortening. 1. An occlusion device comprising: the proximal portion comprises a first hub that has a fixed first diameter;', 'the middle portion has a second diameter and comprises a plurality of beams extending from the first hub to a distal portion, wherein each of the plurality of beams is connected to an adjacent beam by a first circumferentially extending column of strut pairs; and', 'the distal portion has a third diameter; and, 'a framework comprising a proximal portion, a middle portion, and a distal portion, whereina biocompatible covering disposed over at least a part of the framework.2. The occlusion device of wherein the middle portion of the framework is movable between a first configuration wherein the second diameter is not greater than the first diameter and a second configuration wherein the second diameter is greater than the first diameter.3. The occlusion device of wherein each of the plurality of beams is connected to an adjacent beam by a second circumferentially extending column of strut pairs.4. The occlusion device of wherein each beam comprises:a first segment extending from the first hub to the first circumferentially extending column of strut pairs; anda second segment extending from the first ...

Occlusive implant delivery devices and associated methods

The various embodiments simplify the delivery of an occlusive implant to a hollow anatomical structure, such as a fallopian tube. For example, the delivery devices don't need to be retracted manually to deploy the implant. When the devices are activated, stored energy or a powered drive member induces movement of the various components. The operator need only position the distal ends of the devices at the treatment site and then commence deployment by, for example, flipping a switch or changing the position of an activation button. The present embodiments thus increase the efficacy of occlusion procedures by reducing the likelihood of operator error.

FLEXIBLE LOW COMPLIANCE EXTENSION TUBING FOR BALLOON INFLATION

A controlled volume inflation-deflation device to inflate a balloon to occlude a blood vessel by dialing a knob that locks at rotational positions to locate a plunger at equally spaced locations within a syringe of the inflation-deflation device. The inflation-deflation device includes a releasable latch to lock the proximal and distal housings together to hold the plunger forward for occlusion, and to separate and hold the proximal and distal housings to retract the plunger for perfusion. When the inflation-deflation device is returned to the latched position, the balloon is re-inflated to its previous occlusive diameter. Also, an extension tube made of a lower modulus outer material co-extruded over and miscible with a higher modulus inner material may be used to produce a suitably low compliance extension tube for the inflation-deflation device. The balloon may have tapered ends and a cylindrical center portion so that it increases by more equal increments in outer diameter in response to incremental equal increases in inflation volume. 1. An apparatus comprising: a first end having a first connector adapted to couple the flexible tube to an output of the syringe tube;', 'a second end having a second connector to couple the flexible tube to an input adapter of the catheter;', 'an inner material defining a lumen having an inner diameter sufficient to communicate fluid between the syringe tube and the input adapter to cause a volume of fluid to inflate a balloon attached to the catheter to occlude a blood vessel at a region of interest;', 'an outer material surrounding the inner material;', 'wherein the inner material has a modulus of elasticity greater than a modulus of elasticity of the outer material, wherein the inner material and the outer material are miscible and are co-extruded, and wherein the inner diameter of the inner material is less than or equal to 0.035 inches, and the outer diameter of the outer material is greater than or equal to 0.13 inches., 'a ...

System and method for delivering and deploying an occluding device within a vessel

A system and method for deploying an occluding device that can be used to remodel an aneurysm within the vessel by, for example, neck reconstruction or balloon remodeling. The system comprises an introducer sheath and an assembly for carrying the occluding device. The assembly includes an elongated flexible member having an occluding device retaining member for receiving member for engaging a second end of the occluding device and a support surrounding a portion of the elongated flexible member over which the occluding device can be positioned. The elongated flexible member may be a integral portion formed thereof that form a coil portion.

OVER-THE-WIRE INTERLOCK ATTACHMENT/DETACHMENT MECHANISM

The over-the-wire interlock attachment/detachment mechanism includes a cylindrical lock receiving section of a small diameter attached to an implantable medical device such as a blood clot filter, a stent, or a septal occluder. This cylindrical lock receiving section has a plurality of spaced, curved cutouts to receive both the guide fingers and contoured locking fingers formed on a cylindrical locking section. The locking fingers are angled outwardly from the cylindrical body of the cylindrical locking section, and are moved inwardly into engagement with the curved cutouts of the cylindrical lock receiving section by a sheath which slides over the cylindrical locking section or other suitable operator. 1. A method for retrieving a medical implant comprising:accessing a medical implant using a locking mechanism comprising a locking arm, wherein the locking mechanism is enclosed in a sheath, and the implant comprises a cutout section;sliding the sheath away from the locking mechanism to allow the locking arm to angle outwardly from a longitudinal axis of the locking mechanism;positioning the locking arm over the cutout section of the implant;sliding the sheath back over the locking mechanism to lock the locking arm in the cutout section and thereby locking the implant; andretrieving the locking mechanism with the implant.2. The method of wherein the accessing step comprises accessing the implant with a guidewire and passing the locking mechanism over the guidewire.3. The method of wherein the implant is selected from the group consisting of an occluder claim 1 , a filter claim 1 , and a stent. This application is a divisional application of U.S. application Ser. No. 11/200,628 filed Aug. 9, 2005, now pending; which is a divisional application of U.S. application Ser. No. 09/977,971 filed Oct. 17, 2001, now issued as U.S. Pat. No. 6,936,058; which claims the benefit under 35 USC §119(e) to U.S. Application Ser. No. 60/241,005 filed Oct. 18, 2000, now expired. The ...

Method and apparatus for occluding a blood vessel

Apparatus for percutaneously occluding a hollow structure, said apparatus comprising: an occluder, said occluder comprising a first component and a second component, wherein said first component is configured so that it may assume (i) a diametrically-reduced configuration for disposition within the lumen of a hollow tube, and (ii) a diametrically-expanded configuration for disposition adjacent to the hollow structure, whereby to occlude the hollow structure, and further wherein said second component percutaneously connects said first component to a site remote from said first component.

Devices and Methods for Dilating a Paranasal Sinus Opening and for Treating Sinusitis

Medical devices which are adapted to be inserted into a patient for a limited period of time using minimally invasive insertion procedures for dilating a stenotic opening, such as a stenotic sinus opening, are provided. The devices and methods can be used for treating sinusitis and other nasal and/or sinus disorders.

Occlusive devices and methods of use

An aneurysm therapy system, can include a catheter and an occlusive device. The catheter can have a proximal end, a distal end, and a lumen extending between the proximal and distal ends. The proximal end can include a self-expanding distal section, and the distal section can comprise a coil portion. The occlusive device can be disposed within the lumen and configured to reside in the aneurysm to restrict fluid flow within the aneurysm.

Devices and Methods for Dilating a Paranasal Sinus Opening and for Treating Sinusitis

Medical devices which are adapted to be inserted into a patient for a limited period of time using minimally invasive insertion procedures for dilating a stenotic opening, such as a stenotic sinus opening, are provided. The devices and methods can be used for treating sinusitis and other nasal and/or sinus disorders.

Devices and methods for treatment of vascular aneurysms

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Systems and methods for making a laminar ventricular partitioning device

Described herein are systems and methods for securing a polymeric sheet to rib components of a frame structure, wherein the rib components are jointed at a hub to form an expandable and collapsible implant. In general, the method may include the steps of decreasing a diameter of the frame structure; placing the frame structure into an assembly fixture, wherein the assembly fixture is configured to hold the frame structure in a loaded configuration with a decreased diameter; placing a polymeric sheet into the assembly fixture; and heating the assembly under pressure to fuse the sheet to the frame structure. In general, a fixture may include a first and second platen having a shaping portion and a rim portion positioned around the periphery of the platen, wherein the shaping portions are configured to hold the rib components of the frame structure in a loaded configuration with a decreased diameter.

Devices and methods for delivering an endocardial device

Described herein are devices, systems and methods for delivering an endocardial device. The systems for delivering the device transvascularly may generally include an elongate guide catheter having a proximal end and a distal end; a conical dilator at the distal end of the elongate guide catheter, the conical dilator being removable to enable delivery of the ventricular portioning device; a delivery catheter having a proximal and distal end; an expansion member near the distal end of the delivery catheter and configured to expand a plurality of struts of the partitioning device; and a coupling element configured to deployably secure to a hub of the partitioning device. The systems for delivering the device transapically may generally include an elongate access sheath; an elongate delivery catheter; an expansion member; and a coupling element proximal to the expansion member and configured to deployably secure to a hub of the partitioning device.

VASCULAR BANDS AND DELIVERY SYSTEMS THEREFOR

An extra-luminal ring () includes a structural member (), which assumes a first elongate hollow shape () when in a relaxed state; when deformed to a planar state (), generally defines a planar shape () having two first sides (A, B) parallel to each other, and two second sides (A, B) parallel to each other; and when in the relaxed state, is configured such that the two first sides (A, B) are generally straight and parallel with each other, and the two second sides (A, B) are curved at least partially around a first longitudinal axis () defined by the first elongate hollow shape (). The structural member (), when in a deformed state, has a second elongate hollow shape (), different from the first elongate hollow shape (), in which the two second sides (A, B) are generally straight and parallel with each other, and the two first sides (A, B) are curved at least partially around a second longitudinal axis () defined by the second elongate hollow shape (). 1. Apparatus comprising:an extra-luminal ring, which comprises a structural member, which (a) is configured to assume a first elongate hollow shape when in a relaxed state, (b) when deformed to a planar state, generally defines a planar shape having two first sides parallel to each other, and two second sides parallel to each other, and (c) when in the relaxed state, is configured such that (i) the two first sides are generally straight and parallel with each other, and (ii) the two second sides are curved at least partially around a first longitudinal axis defined by the first elongate hollow shape; anda hollow, generally tubular delivery shaft, in which the extra-luminal ring is removably disposed with the structural member in a deformed state, in which state (a) the structural member has a second elongate hollow shape, different from the first elongate hollow shape, (b) the two second sides are generally straight and parallel with each other, and (c) the two first sides are curved at least partially around a second ...

MEDICAL RESTRICTION DEVICE FOR HOLLOW ORGANS OF A BODY

The invention relates to a medical restriction device for hollow organs of a body, having a longitudinal flexible element having a first and a second end, a closure device locking the longitudinal element annularly in a predetermined diameter position, and a tip as an insertion aid at the first end of the longitudinal element for placing the restriction device on the hollow organ, wherein the tip comprises a reinforcing core made of rigid material, wherein an opening is provided at the second end of the longitudinal element as part of the closure device, the tip can be inserted with the first end of the longitudinal element into the opening at the second end of the longitudinal element for locking the closure device, and the tip is fixedly connected to the first end; and can be cut off after locking the longitudinal element by the closure device. 1. A medical restriction device for hollow organs of a body , comprising;a longitudinal flexible element having a first end and a second end,a closure device for locking the longitudinal element annularly in a predetermined diameter position, anda tip as an inlet guide at the first end of the longitudinal element for positioning the restriction device at the hollow organ,whereinthe tip comprises a reinforcing core of rigid material,an opening is provided at the second end of the longitudinal element as a part of the closure device,the tip is adapted to be inserted together with the first end of the longitudinal element into the opening at the second end of the longitudinal element in order to lock the closure device, andthe tip is firmly connected with the first end and can be severed after the longitudinal element has been locked by the closure device.2. The medical restriction device of claim 1 , wherein the closure device is adapted to reversibly lock the longitudinal element in a plurality of diameter positions.3. A medical restriction device for hollow organs of a body claim 1 , comprising;a longitudinal flexible ...

Spring detach joint for delivering a detachable implantable device

Methods and systems for delivering an implantable device to a target site, using a detachable link. The system can include an embolic coil mated to a delivery wire via a detachable link comprising first and second engaging members. When the detachable link is delivered through a catheter, the first and second engaging members are configured to self-detach.

Implant including a coil and a stretch-resistant member

This invention is directed to implantable coils and, more particularly, to a coil implant having a stretch-resistant member internal to the coil. The implant of the invention is able to freely articulate and torque prior to delivery. Once delivered, the implant is no longer stretch resistant and is therefore able to substantially conform to the vascular site.

Therapeutic methods and devices following myocardial infarction

Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.

Vasoocclusive coil with biplex windings to improve mechanical properties

The vasoocclusive device for use in interventional therapy and vascular surgery adapted to be inserted into a portion of a vasculature, includes a vasoocclusive coil disposed about an inner reinforcement coil wherein said vasoocclusive coil is helically wound and the inner reinforcement coil forms a reverse helical winding opposite the vasoocclusive coil winding, thereby forming a biplex wound coil. The vasoocclusive device biplex winding provides improved mechanical properties to the device. An inner reinforcement stretch resistant member attached within the biplex windings limits coil stretchability.

Endovascular Closure Device

An aneurysm closure device that includes a retention assembly, adapted to retain the closure device in place on an aneurysm neck. Also, a seal has a wire frame, defining a set of eyeholes and thread, threaded through the set of eyeholes, to form a lattice. Finally, an expanse of silicone, is cured onto the thread, to form a barrier.

LINER FOR CYROGENIC TREATMENT SYSTEMS

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session. 1. A liner configured for expansion within a uterine cavity , comprising:a flexible membrane which is configured to have a flattened shape when in an unexpanded configuration and a contoured shape which conforms to the uterine cavity when in an expanded configuration,wherein the membrane in the expanded configuration has a length which tapers from a first width to a second width which is smaller than the first width and which is sized to receive an instrument therethrough into an interior of the membrane,wherein the first width comprises a first curved portion and a second curved portion opposite to the first curved portion such that the membrane between the first and second curved portions defines a first region having a first radius,wherein the membrane proximal to the first and second curved portions further defines a second region having a second radius different from the first radius, andwherein the membrane proximal to the second region farther defines a third region having a third radius which is opposite relative to the second radius.2. The liner of wherein the membrane is configured to be pleated to facilitate folding of the membrane for deployment.3. The liner of wherein the membrane has a uniform thickness.4. The liner of wherein the membrane has ...

Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels

Pharmaceutically acceptable hydrogel polymers of natural, recombinant or synthetic origin, or hybrids thereof, are introduced in a dry, less hydrated, or substantially deswollen state and rehydrate in a physiological environment to undergo a volumetric expansion and to affect sealing, plugging, or augmentation of tissue, defects in tissue, or of organs. The hydrogel polymers may deliver therapeutic entities by controlled release at the site. Methods to form useful devices from such polymers, and to implant the devices are provided.

TRANS-ESOPHAGEAL AORTIC FLOW RATE CONTROL

A device and method is provided herein for esophageal impingement of a patients aorta. The device may be inserted into a patients esophagus and positioned at the location where the esophagus passes over the patients aorta. In this position, an actuation device is used to apply pressure to the patients aorta through their esophagus to impinge or occlude the aorta to stop or significantly reduce hemorrhaging. A manually operable actuator handle enables a physician to manipulate a head assembly of the device through three distinct degrees of freedom of movement so as to control placement and direction of force against the patients esophagus and, in turn, their aorta. 1. A device for the esophageal compression of a patient's aorta , comprising:an elongate tube;an actuator handle at a proximal end of said elongate tube; anda head assembly at a distal end of said elongate tube;wherein said actuator handle engages said head assembly to cause said head assembly to move through at least one of three distinct degrees of freedom of movement to apply pressure to a patient's tissue.2. The device of claim 1 , said head assembly further comprising a pair of clamp blades that are mounted to said elongate tube for slidable movement along a first axis that is perpendicular to a second claim 1 , longitudinal axis of said elongate tube claim 1 , and that are mounted to said elongate tube for pivotable movement about said first axis.3. The device of claim 2 , wherein said pair of clamp blades are spring biased away from one another.4. The device of claim 3 , said actuator handle further comprising:a clamp blade pitch control actuator moveably mounted to said handle and engaging said pair of clamp blades to pivot said clamp blades about said first axis; anda clamp blade closing actuator moveably mounted to said handle and engaging said pair of clamp blades to slide said clamp blades along said first axis.5. The device of claim 2 , wherein said head assembly is further pivotable about a ...

EXPANDABLE VASCULAR OCCLUSION DEVICE WITH LEAD FRAMING COIL

A method of treating an aneurysm with an occlusion device having an inner embolic device with a proximal section and a distal section. The distal section has a first stiffness and the proximal section has a second stiffness. Further, the device has an expandable mesh capable of a collapsed position and an expanded position. The mesh can be disposed over, and attached to, a portion of the proximal section of the inner embolic device. The first stiffness is greater than the second stiffness and the inner embolic device comprises a preselected shape which assists in transforming the expandable mesh from the collapsed position to the expanded position. 1. A method of treating an aneurysm using an occlusion device having an inner embolic element with a proximal section and a distal section , and an expandable mesh , comprising the steps of:providing a first stiffness for the distal section;providing a second stiffness for the proximal section different from the first stiffness;disposing the expandable mesh over a portion of the proximal section of the inner embolic element;placing the occlusion device within a vessel of a patient;directing the occlusion device to the aneurysm;deploying the distal section of the inner embolic element into the aneurysm from a catheter;assuming, by the distal section of the inner embolic element, a predetermined shape;permanently deploying the expandable mesh into the aneurysm.2. The method of wherein the distal section of the inner embolic element is a framing coil claim 1 , and further comprising the step of configuring the different stiffness of inner embolic element so that the framing coil is stiffer than the proximal section.3. The method of claim 1 , wherein the distal section has a stiffness that is at least ten times the stiffness of the proximal section.4. The method of claim 1 , wherein the distal section has a stiffness that is up to twenty times stiffer than the proximal section.5. The method of claim 1 , wherein the distal ...

SYSTEM FOR OCCLUSION OF LEFT ATRIAL APPENDAGE

A device for occluding an atrial appendage includes a catheter-deliverable epicardial implant that is detachably secured to a delivery device. The implant includes an inflatable cuff that is positionable about the atrial appendage to an extent that, when adjustably inflated, the cuff physiologically occludes the atrial appendage. Such occlusion addresses health risks associated with atrial fibrillation and cardiac rhythm disorder. 1. An epicardial implant , comprising:a positioning device defining an open interior, wherein the positioning device is configured to be detachably coupled with an implant delivery device such that the positioning device may be detached from the implant delivery device after the epicardial implant is in place about the atrial appendage; andat least one expandable cuff coupled with the positioning device;wherein the positioning device is configured to selectively move the expandable cuff toward and away from an atrial appendage to position the expandable cuff in a desired position relative to the atrial appendage;wherein the at least one expandable cuff is expandable into at least a portion of the open interior of the positioning device following placement of the expandable cuff into the desired position; andwherein the at least one expandable cuff is configured to physically occlude a base of the atrial appendage when expanded.2. The epicardial implant of claim 1 , wherein:the positioning device comprises a first prong that is coupled with a second prong at a hinge that is configured to adjust a distance between the first prong and the second prong, wherein a space between the first prong and the second prong defines the open interior of the positioning device.3. The epicardial implant of claim 1 , wherein:the at least one expandable cuff comprises a plurality of distinct chambers that are sequentially or simultaneously filled with a fluid to expand the at least one expandable cuff.4. The epicardial implant of claim 3 , wherein:the fluid ...

MEDICAL DEVICE FOR MODIFICATION OF LEFT ATRIAL APPENDAGE AND RELATED SYSTEMS AND METHODS

Several embodiments are set forth of devices, systems and methods for modifying an atrial appendage such as a left atrial appendage (LAA). In one embodiment, a medical device includes a frame member and a tissue growth member. The frame member includes a unitary, seamless central portion having a plurality of struts defining a multi-cellular structure and an anchoring system, the plurality of struts extending between and configured to self-expand and directly bias the anchor system to anchor the frame member at least partially within the LAA. With this arrangement, the tissue growth member is attached to the frame member to occlude the LAA. 1. A medical device configured to be positioned within a left atrial appendage of a heart , the medical device comprising:a tissue in-growth portion with a central hub coupled to the tissue in-growth portion, the tissue in-growth portion sized and configured to be positioned against tissue adjacent an opening of the left atrial appendage; anda multi-arm anchor portion including a base arm portion and arms, the base arm portion being coupled to the central hub and extending distally from the central hub to a distal most end thereof such that the arms of the multi-arm anchor portion extend radially outward at the distal most end in a curved manner so that the arms extend proximally toward the cover portion.2. The medical device of claim 1 , wherein the tissue in-growth portion comprises a tissue-ingrowth material configured to promote tissue growth therein.3. The medical device of claim 1 , wherein the arms are configured to self-expand from a constricted position to an expanded position.4. The medical device of claim 1 , wherein the arms of the multi-arm anchor portion are each configured to independently expand and bias against tissue within the left atrial appendage.5. The medical device of claim 1 , wherein the arms extend proximally from the distal most end of the multi-arm anchor portion in a separate and independent manner.6 ...

FILAMENTARY DEVICES FOR TREATMENT OF VASCULAR DEFECTS

Methods for treatment of a cerebral aneurysm within a cerebral vasculature of a patient are described. A microcatheter and a device for treatment of the aneurysm are provided. The device is a self-expanding resilient permeable shell having a plurality of elongate resilient filaments with a woven structure. The plurality of filaments includes small and large filaments. The filaments are bundled and secured to each other at a proximal end. A ratio of the total cross-sectional area of small filaments to the total cross-sectional area of large filaments may be between 0.56 and 1.89. The distal end of the microcatheter is advanced to a region of interest within a cerebral artery. The device is advanced through the lumen and out of the distal end of the microcatheter such that the permeable shell deploys and expands within the cerebral aneurysm. The microcatheter is then withdrawn from the cerebral artery. 1. A method of treating a cerebral aneurysm within a cerebral vasculature of a patient , comprising the steps of:providing a microcatheter having a proximal end, a distal end, and a lumen therebetween; a self-expanding resilient permeable shell having a proximal end, a distal end, a longitudinal axis and further comprising:', 'a plurality of elongate resilient filaments with a woven structure, wherein the plurality of filaments includes small filaments and large filaments, wherein the small filaments have a transverse dimension smaller than the transverse dimension of the large filaments, the woven structure having a radially constrained elongated state configured for delivery within a microcatheter with the thin woven filaments extending longitudinally from the proximal end to the distal end radially adjacent each other along a length of the filaments, wherein the filaments are bundled and secured to each other at a proximal end, wherein a ratio of the total cross-sectional area of small filaments to the total cross-sectional area of large filaments is between 0.56 and ...

ENDOVASCULAR CATHETER WITH MULTIPLE CAPABILITIES

An endovascular catheter combination configured to have multiple capabilities is disclosed. These capabilities include proximal and distal occlusion of a segment of a target blood vessel (such as the carotid artery) thus excluding the segment of the blood vessel from circulation for purposes such as surgical consideration. Another capability includes intravascular shunting of the blood through the excluded portion of the artery during a procedure such as an endarterectomy. Additionally, a microsensor provides a measurement of the rate/volume of blood flow through the distal end of the catheter. In one embodiment, a guidewire is provided with a filtration mesh as an anti-embolic mechanism both at the time of initial positioning of the catheter and after reversing the occlusion. 1. An endovascular catheter comprising:a flexible lumen with a leading end, a trailing end and a central portion disposed between the leading end and the trailing end;a first syringe and a second syringe, each disposed proximate the trailing end;at least one aperture in the central portion, the at least one aperture being fluidly connected to an opening at the leading end thereby providing a bypass;a common carotid balloon operatively connected to the first syringe;an internal carotid balloon operatively connected to the second syringe; andwherein the internal carotid balloon is disposed proximate the leading end and the common carotid balloon is disposed between the internal carotid balloon and the at least one aperture, the internal carotid balloon and the common carotid balloon being spaced apart by a distance.2. The endovascular catheter as recited in claim 1 , further comprising a blood flow sensor disposed at the leading end that monitors blood flow through the at least one aperture.3. The endovascular catheter as recited in claim 1 , further comprising an extendable netting at the leading end.4. The endovascular catheter as recited in claim 3 , wherein the netting is a concave netting.5 ...

DEVICES FOR THE TREATMENT OF VASCULAR ANEURYSM

Devices for the treatment of vascular aneurysms are described. The treatment is achieved through the delivery of an effective amount of elastin stabilization agent to an isolated volume at the aneurysm. The elastin stabilization agent maybe embedded in a delivery composition. The device optionally has an aspiration means to improve the effectiveness of the treatment. 1. A method for treating an isolated portion of a blood vessel , the method comprising:delivering a therapeutic composition to the isolated volume of the blood vessel following aspiration of the fluid using a device that is positioned within the vessel with an extendable portion forming the isolated volume with the wall of the vessel wherein the therapeutic composition is delivered into the isolated volume through a fluid exchange portion in fluid communication with a lumen of the shaft that extends from the patient wherein the flow in the vessel is maintained through a by pass channel of the delivery device while treatment is performed, wherein the therapeutic composition comprises an elastin stabilizing composition.2. The method of wherein the shaft further comprises a rapid exchange guidewire lumen with a guidewire port near the distal end of the shaft.3. The method of wherein the extendable element comprises an actuation element that controls the transition of the extendable element between the lower profile configuration and the extended configuration.4. The method of wherein the fluid exchange portion is on the shaft of the device comprising one or more exchange openings in fluid communication with the isolated volume.5. The method of wherein the one or more exchange openings comprises a tubular conduit displaced from the shaft having an opening that is in fluid communication with the isolated volume.6. The method of wherein the fluid exchange portion comprises a side channel that is a portion of the second lumen having an opening on the side of the sealing element of the device.7. The method of ...

MEDICAL DEVICE DEPLOYMENT SYSTEM

Deployment systems and methods are provided herein for percutaneous transcatheter deployment of medical devices. A medical device deployment system includes a body member and a body locking member that is configured to cooperatively engage along a portion of the body member such that the body member is releasably coupleable to a medical device. 1. A delivery system for delivering a medical device in a body , the delivery system comprising:a body member having a nominal diameter, a distal end, and a proximal end, wherein a distal end portion of the body member has at least one portion having an increased diameter from the nominal diameter of the body member; anda body locking member having a nominal diameter, a distal end and a proximal end, wherein the body locking member is configured to cooperatively engage along at least the distal end portion of the body member such that the body member is releasably coupleable to a medical device.2. The delivery system of claim 1 , wherein the medical device comprises an attachment feature that defines an aperture with an inner diameter claim 1 , wherein the inner diameter of the attachment feature is less than a combined diameter of the body locking member and the portion of the body member having an increased diameter from the nominal diameter when the body locking member is cooperatively engaged along at least the distal end portion of the body member claim 1 , and wherein the inner diameter of the attachment feature is greater than the combined diameter of the body locking member and the nominal diameter of the body member when the body locking member is cooperatively engaged along at least the distal end portion of the body member.3. The delivery system of claim 1 , wherein the medical device comprises an attachment feature that defines an aperture with an inner diameter claim 1 , and wherein the inner diameter of the attachment feature is greater than a diameter of the portion of the body member having an increased ...

Method and apparatus for treating varicose veins

An apparatus for occluding a blood vessel includes an occluder configured so that at least a portion of the occluder may assume (i) a diametrically-reduced configuration for disposition within the lumen of a tube, and (ii) a diametrically-expanded configuration for disposition adjacent to the blood vessel, such that when the at least a portion of the occluder is in its diametrically-expanded configuration adjacent to the blood vessel, the occluder will cause occlusion of the blood vessel.

DEPLOYMENT MECHANISM FOR IMPLANTABLE MEDICAL DEVICES

A system for controlling deployment of an implantable medical includes an implantable medical device and a gripper mechanism. One or both of the medical device and the gripper mechanism are made from a shape-memory alloy material having a temperature at which the material will transition from a martensite state to an austenite state. The shape-memory alloy material has a transition temperature that is higher than a normal body temperature and a wide hysteresis band, with a temperature at which the material transitions back into the martensite state being below a normal body temperature. The medical device will expand or change shape upon being heated by a current passing therethrough, but will not transition into its remembered shape until such current is applied. 1. A medical system for delivering a medical device , the system comprising:an introducer assembly;a gripper mechanism coupled to the introducer assembly, the gripper mechanism having both an open state and a closed state;a resistive element coupled to the introducer assembly and the gripper mechanism, the resistive element configured for being connected to a current source;wherein the gripper mechanism is at least a portion of the resistive element or is coupled to the resistive element;a medical device releasably coupled to the gripper mechanism;wherein the gripper mechanism includes shape memory material, and the gripper mechanism will transition from a martensite state into an austenite state in response to being heated to a final transition temperature via the resistive element, wherein the final transition temperature is higher than a normal human body temperature.2. The system of claim 1 , wherein the medical device is constructed from a shape memory material claim 1 , the shape memory material having a predetermined deployed shape and being formable into a compressed delivery shape relative to the predetermined deployed shape claim 1 , wherein the medical device will transition toward the ...

FLANGED OCCLUSION DEVICES AND METHODS

Implantable occlusion devices that include one or more flanges extending from a tubular body are disclosed. The flange or flanges may assist in retention of the device within a vessel, cavity, appendage, etc. At least one flange on the occlusion device may include a concave surface proximate one end of a body. Because of the shape of the flange, e.g., its concavity, the occlusion device may resist dislocation due to e.g., the forces generated within the left atrial appendage during atrial filbrillation. 117-. (canceled)18. A medical device for deployment in a body , wherein the device comprises:a tubular body comprising a first end and a second end, the body defining a longitudinal axis extending between the first end and the second end, the body comprising a body width measured transverse to the longitudinal axis when the device is in a relaxed configuration; andonly one flange attached to the body proximate the second end of the body, the only one flange comprising a flange width transverse to the longitudinal axis and a concave outer surface facing the first end of the body when the device is in the relaxed configuration,wherein the width of the body proximate the only one flange is less than the width of the flange when the device is in the relaxed configuration.19. The medical device of claim 18 , wherein the concave outer surface is linear in one or more directions.20. The medical device of claim 18 , wherein the concave outer surface is formed from a plurality of flat surfaces joined together.21. The medical device of claim 18 , wherein the flange comprises a convex outer surface facing the second end of the body.22. The medical device of claim 21 , wherein the convex surface faces away from the first end of the body when the device is in the relaxed configuration.23. The medical device of claim 18 , wherein the device comprises a collapsed configuration in which a distance between the first end and the second end is increased such that the body width and the ...

Vaso-occlusive device delivery system

A vaso-occlusive device delivery assembly includes a pusher assembly and a vaso-occlusive device detachably coupled to the pusher assembly by an attachment member is frictionally secured within a lumen of the pusher assembly. A heat generating member is disposed in the pusher assembly lumen, along with a pressure generating material, such that, when heat is generated by the heat generative device, the pressure generating material increases a pressure in the pusher assembly lumen, thereby dislodging the attachment member from the pusher assembly and detaching the vaso-occlusive device from the pusher assembly.

Variable scale stent deployment device

A variable scale medical implant deployment device comprising a variable inner diameter scale sleeve insert is provided. Also described are kits containing the variable scale medical implant deployment device and methods for deploying a medical implant into a body lumen using a variable scale medical implant deployment device.

EMBOLIC COILS AND RELATED COMPONENTS, SYSTEMS, AND METHODS

The present invention relates generally to systems and methods for delivering embolic devices into a body lumen of a patient. These embolic devices are applicable to a variety of neurological and/or peripheral applications. In particular, the embolic devices may be used to occlude a vessel within a patient, and/or to treat aneurysms, arteriovenous malformations, traumatic fistulas, uterine fibroids or cancer. 1. A system for treating a patient , comprising:a catheter having a proximal end, a distal end, and a lumen extending from the proximal end to the distal end;a delivery wire slidably disposed within the lumen, the delivery wire having a proximal end and a distal end; and (a) the proximal end of the embolic device includes a structure expandable between first and second positions relative to the distal end of the catheter,', '(b) the distal end of the delivery wire includes a head with a helical groove on the outer surface of the head configured for enhanced engagement with the structure,', '(c) the structure interfits with the head when in the first position, and', '(d) the structure assumes the second position when the proximal end of the embolic device is positioned distally to the lumen of the catheter., 'an embolic device having a proximal and a distal end, wherein'}2. The system of claim 1 , wherein the head is peanut shaped.3. The system of claim 1 , wherein the structure includes a tubular mesh.4. The system of claim 1 , wherein the head is conical.5. The system of claim 1 , wherein the head is not rotationally symmetrical about a longitudinal axis.6. The system of claim 1 , wherein the head is not rotationally symmetrical about any axis.7. The system of claim 1 , wherein the head includes a radiopaque marker.8. The system of claim 1 , wherein the structures are configured to flex such that the proximal end of the embolic device can be inserted into a catheter having an inner diameter of between 0.018 inches and 0.035 inches.9. The system of claim 1 , ...

DELIVERY SYSTEM INSERTABLE THROUGH BODY LUMEN

A system for delivering a device into a body lumen of a patient, the system including a device having a marker band and a tube at a proximal portion, and a pusher member having a ribbon and a ball or hook at a distal portion of the delivery member and a compression coil positioned over the ribbon, the ball or hook releasably engageable with the tube. 1. A system for delivering a device into a body lumen of a patient , the system comprising:a device having a tube at a proximal portion; anda locking member including an elongated member and a device engaging member at a distal portion of the elongated member, a compression coil positioned over the elongated member to apply a distally directed force on the device, and the engaging member releasably engageable with the tube of the device.2. The system of claim 1 , further comprising a delivery catheter claim 1 , the hood positioned within the delivery catheter.3. The system of claim 1 , wherein the engaging member is in the form of a ball.4. The system of claim 1 , wherein the engaging member is the form of a hook bent transversely with respect to a longitudinal axis of the elongated member.5. The system of claim 1 , wherein the tube has an opening formed therein claim 1 , the engaging member releasably engageable with the opening.6. The system of claim 2 , further comprising a flow diverter positioned within the delivery catheter proximal of the device.7. The system of claim 1 , further comprising a marker band claim 1 , wherein the elongated member is positioned between the compression coil and marker band.8. The system of claim 7 , further comprising a pusher member claim 7 , wherein the elongated member is offset from a central longitudinal axis of the pusher member.9. The system of claim 1 , further comprising a hood positioned over the engaging member to limit transverse motion of the locking member.10. A system for delivering a device into a body lumen of a patient claim 1 , the system comprising:a device having a ...

GUIDE CATHETER AND METHOD OF USE

A system for manipulating a guide catheter within a patient's nasal passages or sinus cavities includes a guide catheter formed from an elongate flexible member having a lumen passing there through. A wire guide is slidably disposed within the lumen of the guide catheter. The system further includes a steering member fixedly secured to a proximal end of the wire guide and a proximal hub secured to a proximal end of the guide catheter. The system further includes a recessed handle having a first recess for fixedly receiving the proximal hub of the guide catheter and a second recess for receiving the steering member, the second recess being dimensioned to permit axial and rotational movement of the steering member while disposed in the second recess. 118-. (canceled)19. A system for dilating tissue of a drainage pathway of a sinus cavity of a patient comprising:a guide catheter secured to a handle and extending distally therefrom, the handle defining a recess that opens along a side surface of the handle in a longitudinal direction;a steering device configured to slide along the recess in a direction parallel to the longitudinal direction and further configured to rotate;a wire guide extending through the guide catheter and the steering device, wherein rotation of the steering device effectuates rotation of the wire guide through complete revolutions while the steering device is positioned within the steering device recess; anda balloon catheter comprising an inflatable balloon.20. The system of claim 19 , wherein the proximal end of the guide catheter includes a hub and wherein the handle comprises a hub recess configured to receive the hub.21. The system of claim 20 , wherein the hub recess is located on a distal end of the handle.22. The system of claim 21 , wherein the guide catheter is releasably secured to the hub recess by at least one of detents or tabs.23. The system of claim 21 , wherein the guide catheter is releasably secured to the hub recess by a ...

CONFINEMENT OF KIDNEY STONE FRAGMENTS DURING LITHOTRIPSY

The present invention improves significantly the success rate of lithotripsy and reduces the risk of tissue damage, by injecting a temporary plug in front, and optionally behind a concretion (for extracorporeal lithotripsy) or behind a concretion (for intracorporeal lithotripsy). One aspect of the present invention relates to injecting an inverse thermosensitive polymer solution into a lumen, thereby preventing the migration of a concretion, or its fragments, upon extracorporeal or intracorporeal lithotripsy.

NOVEL INTRA UTERINE DEVICE

The present invention discloses an Intra Uterine Ball (IUB) device useful for a gynecological procedure or treatment. The aforesaid device comprises a hollow sleeve for at least partial insertion into the uterine cavity; and, an elongate conformable member with at least a portion comprised of shape memory alloy. The elongate member is adapted to be pushed out from said sleeve within said uterine cavity. It is the core of the invention that the elongate member is adapted to conform into a predetermined three dimensional ball-like configuration within said uterine cavity following its emergence from said sleeve, such that expulsion from said uterine cavity, malposition in said uterine cavity, and perforation of the uterine walls is prevented. 1. A device positionable within the uterine cavity comprising a wire having two free ends and at least two loop-like structures formed between said free ends , wherein a first loop is approximately perpendicular with , and positioned through , a second loop thereby forming a three dimensional structure capable of elastically contracting and expanding in response to contraction and expansion of the uterine cavity.2. The device of claim 1 , wherein said wire is linearizable by pulling a free end of said two free end through a tube.3. The device of claim 1 , wherein at least a portion of said wire is coated with a contraceptive agent.4. The device of claim 1 , wherein said three dimensional structure has a diameter of about 10 mm to about 15 mm.5. The device of claim 1 , wherein said wire is composed of Nitinol.6. The device of claim 3 , wherein said contraceptive agent is copper or a contraceptive hormone.7. A method of positioning a device in a uterine cavity comprising:(a) providing a device formed from a wire having two free ends and at least two loop-like structures between said free ends, wherein a first loop is approximately perpendicular with, and positioned through, a second loop thereby forming a three dimensional ...

IMPLANTABLE MEDICAL DEVICE DETACHMENT SYSTEM WITH SPLIT TUBE AND CYLINDRICAL COUPLING

A method of constructing a detachment system for delivering an implantable medical device to a target location of a body vessel is presented. The method includes forming a compressible portion on a distal tube, engaging an implantable medical device with an engagement system, extending the engagement system through the distal tube such that the implantable medical device is distal of a distal end of the distal tube, applying a force to the engagement system to compress the compressible portion to a compressed state, fixing the engagement system to the distal tube to maintain the compressed state of the compressible portion, and joining a proximal end of the distal tube to a distal end of a proximal tube. The engagement system can include a loop wire that is fixed to the distal tube and engages the medical device. 1. A method comprising:forming a compressible portion on a distal tube between a proximal end of the distal tube and a distal end of the distal tube;engaging an implantable medical device with an engagement system;extending the engagement system through the distal tube such that the implantable medical device is distal of the distal end of the distal tube;applying a force to the engagement system to compress the compressible portion to a compressed state;fixing the engagement system to the distal tube to maintain the compressed state of the compressible portion; andjoining the proximal end of the distal tube to a distal end of a proximal tube.2. The method of claim 1 , further comprising:affixing a coupling to the proximal end of the distal tube and the distal end of the proximal tube, thereby joining the proximal end of the distal tube to the distal end of the proximal tube.3. The method of claim 1 , further comprising:fixing the engagement system to the distal tube approximate the proximal end of the distal tube.4. The method of claim 1 , further comprising:extending a loop wire of the engagement system through the distal tube; andengaging the loop wire ...

SYSTEMS AND METHODS FOR DELIVERY OF GEL EMBOLICS

Delivery systems for liquid embolics and methods of using them are disclosed. The devices generally include a catheter and one or more retention elements to limit migration of the liquid embolic to non-target sites. 120.-. (canceled)21. A system for treating a patient , the system comprising:a catheter;at least one retention element slidably disposed within the catheter;an embolic material flowable or slidable through a lumen of the catheter; anda pushrod comprising an elongate body slidably disposed within the catheter;wherein the system is configured such that when catheter is positioned in a body lumen and the catheter is retracted relative to the pushrod or the pushrod is advanced relative to the catheter, the at least one retention element and the embolic material are delivered from the catheter into the body lumen; andwherein the at least one retention element is configured to move from an unexpanded configuration to an expanded configuration within the body lumen and retain the embolic material substantially proximal to the at least one retention element within the body lumen.22. The system of claim 21 , wherein the embolic material absorbs water when disposed in an aqueous environment.23. The system of claim 21 , wherein the embolic material forms a gel.24. The system of claim 21 , wherein the embolic material is a superabsorbent polymer plug.25. The system of claim 21 , wherein the at least one retention element comprises a first retention element and a second retention element disposed proximally and distally about the embolic material claim 21 , respectively.26. The system of claim 21 , wherein the first retention element and the second retention element are connected to one another by an elongate member extending between them.27. The system of claim 21 , comprising a link disposed on an end of the pushrod claim 21 , the link detachably connecting the end of the pushrod to the first retention element.29. The system for treating a patient of claim 28 , ...

Device and System for Restricting Fluid Flow in Physiological Vessels

Provided is a device and system for restricting fluid flow in physiological vessels of humans or animals, the device being configurable in a first mode to be passively propellable by fluid flow within a physiological vessel and in a second mode to at least partially occlude a physiological vessel, the device having a first cross-sectional size in the first mode and a second cross-sectional size in the second mode, wherein the second cross-sectional size is greater than the first cross-sectional size. The system comprises: a plurality of the devices described above, a power source for powering the devices; and a controller comprising one or more processors for controlling the devices.

UNIVERSAL RETRIEVAL DEVICE FOR REMOVING OBSTRUCTIONS FROM BODY LUMENS

Embodiments of the present disclosure are directed to devices and methods for object retrieval in a body lumen. In some embodiments, disclosed herein is a retrieval device including a catheter; a strut shaft; a basket comprising a plurality of struts and a collapsible pouch; and an actuation mechanism. 1. A retrieval device , comprising:a catheter having at least one catheter lumen, a proximal end and a distal end;a strut shaft having a proximal end and a distal end, wherein the catheter substantially surrounds the strut shaft, and wherein the catheter can move axially relative to the strut shaft; a plurality of struts, each having a proximal end and a distal end, wherein the proximal end of each strut is attached to the distal end of the strut shaft and the distal ends of the struts form a frame; and', 'a collapsible pouch, wherein the collapsible pouch is flexibly connected to the distal end of each of the struts; and, 'a basket, wherein the basket is configured to be axially insertable into the catheter lumen, and comprisinga device control portion having a proximal end and a distal end, wherein the distal end is connected to the proximal end of the catheter.2. The retrieval device according to claim 1 , further comprising:a wedge shaft having a proximal end and a distal end; anda wedge, the wedge is attached to the distal end of the wedge shaft; and', 'the strut shaft substantially surrounds the wedge shaft., 'wherein3. The retrieval device according to claim 2 , wherein the device control portion is a handle.4. The retrieval device according to claim 3 , wherein the handle further comprises:a stationary handle piece having a proximal end and a distal end, and having one or more finger rings; anda moveable handle piece having one or more finger rings, 'the moveable handle piece is configured to move axially relative to the stationary handle piece.', 'wherein5. The retrieval device according to claim 4 , wherein the proximal end of the strut shaft is coupled to ...

STENT WITH EXPANDABLE FOAM

A stent for treating a physical anomaly. The stent includes a skeletal support structure for expanding in the physical anomaly and a shape memory material coupled to the skeletal support structure. 1. A system comprising:a first shape memory polymer (SMP), the first SMP including a first SMP foam;a second SMP, the second SMP including a second SMP foam;wherein the first SMP foam: (a)(i) is an open cell foam, (a)(ii) is biodegradable, (a)(iii) includes a first channel, and (a)(iv) includes two or more members selected from the group comprising Hexamethylene diisocyanate (HDI), triethanolamine (TEA), or hydroxypropyl ethylenediamine (HPED);wherein the second SMP foam: (b)(i) is cylindrical, (b)(ii) includes a second channel, and (b)(iii) is included in the first channel; andwherein: (c)(i) the first SMP foam is in a first state; and (c)(ii) the first SMP foam is configured to expand to a second state, radially outward from the second SMP foam, in response to thermal stimulus.2. The system of wherein:{'sub': 'g', 'the first SMP foam has a glass transition temperature (T) between 30° C. and 86° C.;'}the first SMP foam is cross-linked; andthe first SMP foam is configured to have, in the second state, a volumetric void fraction greater than 98% and less than 100%.3. The system of comprising a third SMP claim 2 , wherein the third SMP is between the first and second SMP foams.4. The system of wherein the third SMP includes a stent having a first strut that includes the third SMP and a second strut that includes the third SMP.5. The system of comprising a fourth SMP claim 3 , wherein:the third SMP is between the fourth SMP and the second SMP;the second SMP is not monolithic with the first SMP;the second SMP is not monolithic with the third SMP;the fourth SMP is not monolithic with the second SMP;the fourth SMP is cured.6. The system of comprising a third SMP claim 2 , wherein:the second SMP foam is between the third SMP and the first SMP foam;the third SMP is cured and the ...

Expandable implant devices for filtering blood flow from atrial appendages

Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.

DEVICES AND METHODS FOR TREATMENT OF VASCULAR ANEURYSMS

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm. 1. A system for treating an aneurysm comprising:a catheter delivery system having a distal tip; anda filler passable through the distal tip, wherein when the filler is in a deployed configuration, the filler is between a first leg of a bifurcated stent and a wall of the aneurysm, and wherein when the filler is in the deployed configuration, the filler is between a second leg of the bifurcated stent and the wall of the aneurysm.2. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler contacts the first and second legs of the bifurcated stent.3. The system of claim 2 , wherein when the filler is in the deployed configuration claim 2 , the filler contacts the wall of the aneurysm.4. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler contacts the wall of the aneurysm.5. The system of claim 4 , wherein when the filler is in the deployed configuration claim 4 , the filler contacts at least one of the first and second legs of the bifurcated stent.6. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , a portion of the filler is between ...

DEVICES AND METHODS FOR TREATMENT OF VASCULAR ANEURYSMS

The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In one embodiment, a system for treating an aneurysm is disclosed. The system comprises a catheter delivery system, an expandable foam configured to pass through the catheter delivery system, and a stent having a first end and a second end. The stent is configured to extend across the aneurysm. The expandable foam is configured to expand in the aneurysm when exposed to a fluid. 1. A system for treating an aneurysm comprising:a catheter delivery system having a distal tip; anda filler passable through the distal tip into a first fillable space and into a second fillable space, wherein when the filler is in a deployed configuration, the filler is in the first and second fillable spaces, and wherein the first fillable space is at a proximal end of the aneurysm and the second fillable space is at a distal end of the aneurysm.2. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the ii first fillable space and the second fillable space are separate from each other.3. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the first fillable space is connected to the second fillable space.4. The system of claim 1 , wherein before the filler is deployed claim 1 , the first fillable space is separate from the second fillable space.5. The system of claim 4 , wherein after the filler is deployed claim 4 , the first fillable space is connected to the second fillable space.6. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler is a continuous structure.7. The system of claim 1 , wherein when the filler is in the deployed configuration claim 1 , the filler contacts two distal legs of a bifurcated stent.8. The system of claim 7 , wherein when the filler is in the ...

EMBOLIC COIL DELIVERY SYSTEM WITH RETRACTABLE MECHANICAL RELEASE MECHANISM

An embolic implantation system configured to deliver an embolic implant intravascularly to a treatment site includes an elongated delivery tube to which the embolic implant is detachably attached by a flexible loop extending through a retaining ring or opening on the embolic implant and an elongated detachment member or pull wire extending through the delivery tube and flexible loop. The pull wire has a bump near its distal end that inhibits the pull wire from moving further distally when the bump presses distally against the flexible loop and/or retaining ring. The flexible loop and retaining ring thereby serve as a distal obstruction obstructing distal movement of the bump and thereby distal movement of the pull wire into the implant. 1. An embolic implantation system comprising:an elongated delivery tube configured to traverse vasculature and comprising a lumen therethrough;an embolic implantable device comprising a retaining ring;a flexible loop engaged to the elongated delivery tube and extending through the retaining ring;an elongated detachment member being slidably disposed within the lumen of the delivery tube and the flexible loop so that the embolic implantable device is thereby engaged to the delivery tube and the elongated detachment member is slidable in a proximal direction to exit the flexible loop so that the flexible loop can exit the retaining ring, the elongated detachment member comprising a distal bump extending therefrom; anda distal obstruction positioned approximate a distal end of the delivery tube and shaped to engage the distal bump to obstruct distal movement of the distal bump when the distal obstruction is engaged to the distal bump.2. The embolic implantation system of claim 1 , wherein the distal obstruction comprises the flexible loop and the retaining ring when the embolic implantable device is engaged to the delivery tube.3. The embolic implantation system of claim 2 , further comprising: 'wherein the elongated detachment member ...

STENT WITH EXPANDABLE FOAM

A stent for treating a physical anomaly. The stent includes a skeletal support structure for expanding in the physical anomaly and a shape memory material coupled to the skeletal support structure. 1a first shape memory polymer (SMP), the first SMP including a SMP foam;a second SMP;wherein the SMP foam: (a)(i) is an open cell foam, (a)(ii) is biodegradable, (a)(iii) includes a first channel, and (a)(iv) includes a reaction product of a diisocyanate, triethanolamine (TEA), and hydroxypropyl ethylenediamine (HPED);wherein the second SMP: (b)(i) is a cylindrical stent having a first strut that includes the second SMP and a second strut that includes the second SMP, (b)(ii) includes a second channel, and (b)(iii) is included in the first channel;wherein: (c)(i) the SMP foam is in a first state; and (c)(ii) the SMP foam is configured to expand to a second state, radially outward from the second SMP, in response to thermal stimulus;wherein the first SMP is crimped and the second SMP is crimped;wherein the SMP foam has a glass transition temperature (Tg) between 30° C. and 86° C.;wherein the SMP foam is a thermoset polyurethane polymer;wherein the first SMP is coupled to a wire and the second SMP is coupled to the wire.. A system comprising: This application is a Continuation of U.S. patent application Ser. No. 16/139,365, filed Sep. 24, 2018, which is a Continuation of U.S. patent application Ser. No. 14/797,973, filed Jul. 13, 2015, entitled “Stent with Expandable Foam”, which issued on Sep. 25, 2018 as U.S. Pat. No. 10,080,642, which is a Continuation of U.S. patent application Ser. No. 13/892,492, filed May 13, 2013, entitled “Stent with Expandable Foam”, which issued on Jul. 14, 2015 as U.S. Pat. No. 9,078,738, which is a continuation of U.S. patent application Ser. No. 13/010,055, filed Jan. 20, 2011, entitled “Stent with Expandable Foam”, which issued on May 28, 2013 as U.S. Pat. No. 8,449,592, which is a Continuation-in-Part of U.S. patent application Ser. No. 11/ ...

VASO-OCCLUSIVE DEVICES HAVING EXPANDABLE FIBERS

This is a device for occluding a space, for example an aneurysm, within the body. In particular, the device comprising a metallic vaso-occlusive device and expandable fibrous elements. The devices may be placed in a desired site within a mammal. 119-. (canceled)20. An occlusive device having a single expandable material disposed about a portion of the occlusive device.21. The occlusive device of claim 20 , wherein the expandable material is loosely wrapped about a portion of the occlusive device.22. The occlusive device of claim 20 , wherein a portion of the expandable material is interlaced between adjacent windings of the occlusive device.23. The occlusive device of claim 20 , wherein the expandable material contacts the occlusive device in two or more places.24. The occlusive device of claim 20 , wherein the occlusive device is an embolic coil claim 20 , the embolic coil comprising a metal selected from the group consisting of nickel claim 20 , titanium claim 20 , platinum claim 20 , gold claim 20 , tungsten claim 20 , iridium and alloys or combinations thereof.25. The occlusive device of claim 24 , wherein the metal is nitinol or platinum.26. The occlusive device of claim 20 , wherein the occlusive device includes a tubular braid.27. The occlusive device of claim 20 , further comprising at least one bioactive material.28. An occlusive device having an expandable monofilament disposed about an exterior surface of the occlusive device.29. The occlusive device of claim 28 , wherein the expandable monofilament is loosely wrapped about a portion of the occlusive device.30. The occlusive device of claim 28 , wherein a portion of the expandable monofilament is interlaced between adjacent windings of the occlusive device.31. The occlusive device of claim 28 , wherein the expandable material contacts the occlusive device in two or more places.32. The occlusive device of claim 28 , wherein the occlusive device is an embolic coil claim 28 , the embolic coil comprising a ...

Bronchoscopic repair of air leaks in a lung

Systems and devices for minimally invasively treating an air leak in a lung comprise the steps of detecting an air leak in a lung; locating an airway in fluid communication with the air leak, introducing a bronchoscope into a patient's airway to a position adjacent the target section and occluding an airway upstream of the air leak for a period of time. The airway occlusion device is preferably removed after the air leak has substantially permanently healed. The occluding device may be a one-way valve. The occluding device may also comprise strut members and anchors that penetrate an airway wall.

REMOVABLE LUNG REDUCTION DEVICES, SYSTEMS, AND METHODS

An air passageway obstruction device includes a frame structure and a flexible membrane overlying the frame structure. The frame structure is collapsible upon advancement of the device into the air passageway, expandable into a rigid structure upon deploying in the air passageway and recollapsible upon removal from the air passageway. The flexible membrane obstructs inhaled air flow into a lung portion communicating with the air passageway. The device may be removed after deployment in an air passageway by recollapsing the device and pulling the device proximally through a catheter. 1an elongated frame assembly comprising a proximal end and a distal end;the elongated frame assembly further comprising a plurality of support members extending in a proximal direction from the distal end, each of the plurality of support members comprising a bent portion, the bent portion being positioned along a distal portion of each of the plurality of support members;a flexible membrane overlying at least the distal portion of each of the plurality of support members including the bent portion;a proximally positioned concave recess being defined at least in part by the plurality of support members and the flexible membrane, the proximally positioned concave recess comprising a proximally facing opening;at least one anchor being distally positioned relative to the flexible membrane;the device defining an obstructing structure configured to be implanted into the air passageway upstream from a target region, the device being configured to be deployed in the air passageway such that the device precludes air from flowing into the target region past the device while allowing air to flow out of the target region along a path between a portion of the flexible membrane and a wall of the air passageway.. A device for limiting air flow in an air passageway, the device comprising: This application is a continuation of U.S. application Ser. No. 13/787,052, filed Mar. 6, 2013, which is a ...

Contraceptive devices and methods

Contraceptive devices that provide substantially immediate and permanent sterilization are described herein. Systems and methods for transcervically delivering the contraceptive devices are also described herein. The contraceptive device may include an expandable implant. The implant includes hydrogel to provide substantially immediate sterilization, and tissue in-growth fibers to provide permanent sterilization. As an alternative or in combination to hydrogel, the implant may include copper or cupric ions to provide substantially immediate sterilization. The implant may also include hydrogel to improve trackability of the implant through an ovarian pathway.

Magnetic Device To Control Obesity And Related Method Of Use

A medical device includes an outer shell defining a cavity, wherein the shell is movable between a deformed and unstressed state, a magnet disposed within the cavity, and a filler material carried within the cavity conforming to the interior shape of the shell in the unstressed state and being capable of holding its shape in the deformed state. The filler material converts from the deformed state to the unstressed state at a temperature not greater than human body temperature. 121-. (canceled)23. The system of claim 22 , wherein the medical device is insertable through the lumen into a stomach in the deformed state.24. The system of claim 23 , wherein the medical devices are permitted to revert to the unstressed state when released into the stomach.25. The system of claim 22 , wherein the magnets of the medical devices are selected to draw the medical devices together in a cluster within the stomach.26. The system of claim 22 , wherein the filler material is selected from the group comprising a fluid claim 22 , a gel and a paste.27. The system of claim 22 , wherein the shell is substantially elipsoidal when in the deformed state.28. The system of claim 22 , wherein the shells of the medical devices are flexible.29. The system of claim 22 , wherein the magnet in at least one of the medical devices is rod shaped.30. The system of claim 22 , wherein the shell includes at least one flat surface.31. The system of claim 22 , wherein at least one of the shell claim 22 , the magnet and the filler material includes a radiopaque material.32. The system of claim 22 , wherein each medical device further includes an electronic circuit.33. The system of claim 22 , wherein each medical device further includes a sensor to identify parameters of one of a stomach in which the medical device is inserted and the medical device.34. The system of claim 32 , wherein the sensor is a pH sensor.35. The system of claim 22 , wherein the shell includes an antibiotic coating on an outer surface ...

Flexible vascular occluding device

A vascular occluding device for modifying blood flow in a vessel, while maintaining blood flow to the surrounding tissue. The occluding device includes a flexible, easily compressible and bendable occluding device that is particularly suited for treating aneurysms in the brain. The neurovascular occluding device can be deployed using a micro-catheter. The occluding device can be formed by braiding wires in a helical fashion and can have varying lattice densities along the length of the occluding device. The occluding device could also have different lattice densities for surfaces on the same radial plane.

AUTOSTABLE BICANALICULAR PROBE

A bicanalicular probe intended to be inserted into the nasolacrimal duct of a patient including a central tubular part made from a material compatible with insertion into the human body, preferably silicone, and two termination parts each fixed to one end of the central tubular part , characterized in that the two thickened parts project from the central tubular part, the two thickened parts being firstly at a distance from each other and secondly each at a distance from the ends where the termination parts are attached. 1145236723. A bicanalicular probe intended to be inserted into the nasolacrimal duct of a patient , comprising a central tubular part () made from a material compatible with insertion into the human body , preferably silicone , and two termination parts ( , ) each fixed to the central part so that they project from the two respective ends ( , ) of the central tubular part , characterized in that two thickened parts ( , ) at a distance from one another form projections from the central tubular part , the two thickened parts each being at a distance from the respective ends ( , ) of the central tubular part.267. A probe according to claim 1 , characterized in that the two thickened parts ( claim 1 , ) are in the form of two tubes fixed around the central tubular part.3. A probe according to claim 1 , characterized in that the distance along the tube between the two thickened parts claim 1 , that is the two tubes claim 1 , corresponds to a central segment of length between 30 mm and 40 mm.4. A probe according to claim 1 , characterized in that the two thickened parts claim 1 , that is the two tubes claim 1 , extend along the tube for a length of between 4 mm and 8 mm.5. A probe according to claim 4 , characterized in that the two thickened parts claim 4 , that is the two tubes claim 4 , extend along the tube for a length of between 5 mm and 7 mm.623. A probe according to claim 1 , characterized in that the two thickened parts claim 1 , that is the two ...

IMPLANT RETRIEVAL SYSTEM

Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed. 1. A retrieval catheter for retrieving a device from an implantation site within the body, comprising: an elongate, flexible body, having a proximal end and a distal end; a grasping structure on the distal end, for grasping the device; a flared tubular sleeve, for surrounding at least a portion of the device; and an outer tubular sleeve, for surrounding the flared tubular sleeve. This application is a continuation of U.S. patent application Ser. No. 13/617,308, filed Sep. 14, 2012, which is a continuation of U.S. patent application Ser. No. 10/441,600, filed May 19, 2003, now U.S. Pat. No. 8,287,563, which is a divisional of U.S. patent application Ser. No. 10/033,371, filed Oct. 19, 2001, now U.S. Pat. No. 7,044,134, which is a continuation-in-part of U.S. patent application Ser. No. 09/435,562, filed Nov. 8, 1999, now U.S. Pat. No. 7,128,073, the disclosures of which are incorporated in their entirety herein by reference.Embolic stroke is the nation's third leading killer for adults, and is a major cause of disability. There are over 700,000 strokes per year in the United States alone. Of these, roughly 100,000 are hemoragic, and 600,000 are ischemic (either due to vessel narrowing or to embolism). The most common cause of embolie stroke emanating from the heart is thrombus formation due to atrial fibrillation. Approximately 80,000 strokes per year are attributable to atrial fibrillation. Atrial fibrillation is an arrhythmia of the heart that results in a rapid and chaotic heartbeat that produces lower cardiac output and irregular and turbulent blood flow in the vascular system. There are over five million people worldwide with atrial fibrillation, with about four hundred thousand new ...

VASCULAR EMBOLIZATION DEVICE AND PRODUCTION METHOD THEREFOR

A vascular embolization device includes a coil with a primary shape and an stretch resistant wire provided inside the coil, in which the stretch resistant wire is a multilayer strand including at least one core layer and at least one outer layer including one or more resin compositions and a biochemical active material, and the core layer is composed of a material with a tensile break strength higher than that of the outer layer. The vascular embolization device has the function of administering a biochemical active material and also has good flexibility. 1. A vascular embolization device comprising: a coil with a primary shape; and a stretch resistant wire provided in an inside of the coil , wherein the stretch resistant wire is a multilayer strand including at least one core layer and at least one outer layer including one or more resin compositions and a biochemical active material , and the core layer is composed of a material with a tensile break strength higher than that of the outer layer.2. The vascular embolization device according to claim 1 , which has a structure in which the coil with the primary shape is further wound into a secondary shape.3. The vascular embolization device according to or claim 1 , wherein the resin composition comprises at least one of a biodegradable resin and an ethylene-vinyl acetate copolymer.4. The vascular embolization device according to claim 3 , wherein the biodegradable resin has a weight average molecular weight of 1 claim 3 ,000 to 200 claim 3 ,000.5. The vascular embolization device according to claim 3 , wherein the ethylene-vinyl acetate copolymer has a vinyl acetate unit content of 10 to 50% by weight.6. The vascular embolization device according to claim 1 , wherein the stretch resistant wire has a thickness of 0.01 to 0.10 mm.7. The vascular embolization device according to claim 1 , wherein the stretch resistant wire has a break strength of at least 0.05 N per wire.8. The vascular embolization device according to ...

IMPLANTABLE MEDICAL DEVICE DETACHMENT SYSTEM WITH SPLIT TUBE AND CYLINDRICAL COUPLING

A method of constructing a detachment system for delivering an implantable medical device to a target location of a body vessel is presented. The method includes forming a compressible portion on a distal tube, engaging an implantable medical device with an engagement system, extending the engagement system through the distal tube such that the implantable medical device is distal of a distal end of the distal tube, applying a force to the engagement system to compress the compressible portion to a compressed state, fixing the engagement system to the distal tube to maintain the compressed state of the compressible portion, and joining a proximal end of the distal tube to a distal end of a proximal tube. The engagement system can include a loop wire that is fixed to the distal tube and engages the medical device. 1. A detachment system comprising:a generally hollow distal tube defining a longitudinal axis and comprising a distal end, a first flexible portion, and a second flexible portion comprising interference spiral cuts throughout and positioned between the first flexible portion and the distal end; and wherein the engagement system compresses the second flexible portion along the longitudinal axis to a greater extent than the first flexible portion when engaging the implantable medical device; and', 'wherein the second flexible portion is configured to extend along the longitudinal axis to a greater extent than the first flexible portion when the engagement system deploys the implantable medical device., 'an engagement system configured to engage an implantable medical device to the distal end of the distal tube and configured to deploy the implantable medical device from the distal end of the distal tube,'}2. The detachment system of claim 1 , whereinthe first flexible portion comprises interference spiral cuts having a first pitch; and 'wherein the first pitch is different than the second pitch.', 'the second flexible portion comprises interference spiral ...

Implant Delivery System

A system and method of delivering and detaching an implant within a body of a patient is described. A tether connects an implant with a delivery device. The delivery device includes a heater coil through which the tether passes. The inner diameter of the heater coil is about the same size or slightly larger than the outer diameter of the tether, allowing the tether to more efficiently break the tether during delivery. 1. An implant delivery system comprising:a pusher member having an elongated shape;a distal end of the pusher member connectable to the implant;a tether connected to the pusher member and to the implant;a resistance-type heating element mounted over the tether, the heating element having a first plurality of loops with a first internal diameter and a second plurality of loops with a second internal diameter smaller than the first internal diameter;the tether passing through the first plurality of loops and the second plurality of loops; anda sleeve over the second plurality of loops of the heating element.2. The implant delivery system of further comprising a first electrical wire connected at a distal end of the heater element and a second electrical wire connected at a proximal end of the heater element claim 1 , wherein the first electrical wire and the second electrical wire supply direct current between the proximal end of the heater element and the distal end of the heater element.3. The implant delivery system of wherein the sleeve contains a space which accommodates the first electrical wire.4. The implant delivery system of further comprising a second sleeve positioned over said resistance-type heating element.5. The implant delivery system of wherein the sleeve spans the entire the heating element.6. The implant delivery system of wherein the first plurality of loops with the first internal diameter are proximal and distal of the second plurality of loops with the second internal diameter.7. An implant delivery system comprising:a pusher ...

DEVICES AND METHODS FOR OCCLUDING OR PROMOTING FLUID FLOW

Devices and methods for occluding or promoting fluid flow through openings are disclosed. In one exemplary embodiment an occlusion device is provided having an expandable outer elongate tubular body, a guide member extending from a distal end of the outer body, and a slide tube disposed within the outer body, the proximal portions of the outer body and the slide tube being fixedly mated. The slide tube is configured to slide distally within the outer tubular body when the tubular body is expanded to form wings. A tether can be included as part of the device and it can be used to assist in positioning and locking a location of the device in an opening. Exemplary methods for delivering devices disclosed herein are also provided. 1. A method for repairing a valve , the method comprising:advancing a first tubular assembly into a first opening within a first portion of a valve, the first tubular assembly having a first elongate tubular body and a first inner tube extending partially therethrough, the first elongate tubular body having distal and proximal portions;applying force to the first elongate tubular body to move the first elongate tubular body relative to the first inner tube to thereby cause the distal and proximal portions of the first elongate tubular body to expand and form respective distal and proximal wings;advancing a second tubular assembly into a second opening within a second portion of the valve, the second tubular assembly having a second elongate tubular body and a second inner tube extending partially therethrough, the second elongate tubular body having distal and proximal portions;applying force to the second elongate tubular body to move the second elongate tubular body relative to the second inner tube to thereby cause the distal and proximal portions of the second elongate tubular body to expand and form respective distal and proximal wings; andmoving the first and second tubular assemblies toward each other to bring the first and second ...

Cyrogenic treatment systems

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.

Minimally invasive methods and apparatus

Methods and apparatus are provided to facilitate the minimally invasive removal of tissue biopsies and to facilitate the direct approach to anesthetizing the chest wall, in accordance with embodiments of the present invention. A pull-type cutting device 1 comprises two coaxially nested tubes, each extending from a proximal end 21 to a distal end 22 . The first tube 61 defines a guide wire lumen 23 for slidingly receiving a guide wire. The second tube 63 extends over the first tube 60 and coupled thereto at the distal end 22 defining an expandable portion 13 adjacent the distal end 22 . The second tube 63 defines an inflation lumen 25 extending from the shaft proximal end 21 to the expandable portion 13 . The inflation lumen 25 communicates inflation fluid from the proximal end 21 to the expandable portion 13 so as to inflate and deploy the expandable portion 13 . Disposed adjacent the shaft distal end 22 is a cutting head 10 comprising the expandable portion 13 having a cutting portion 11 distal from the shaft distal end 22.

System And Method For Implant Delivery

An implant delivery system is described. The implant delivery system utilizes an implant, implant wire, delivery sheath, and a torque device. The torque device may include a cutting element to slit the delivery sheath and a clamp device to fix the position of the implant delivery wire. 1. An implant delivery device , comprising:a delivery sheath having an interior lumen;an implant connected to an elongated implant wire; said implant and said elongated implant wire sized for deployment through said delivery sheath;a torque device having a first passage, a cutting element positioned to cut said delivery sheath, and a second passage splitting off from said second passage so as to separate said delivery sheath from said elongated implant wire.2. The implant delivery system of claim 1 , wherein said torque device further comprises a clamp mechanism configured to prevent said elongated implant wire from movement relative to said torque device.3. The implant delivery system of claim 2 , wherein said clamp mechanism further comprises a collet and a screw member that is selectively contactable with said collet claim 2 , so as to increase or decrease an interior diameter of said collet.4. The implant delivery system of claim 3 , wherein said screw member is threaded onto a proximal end of a body of said torque device.5. The implant delivery system of claim 1 , wherein said cutting element comprises a sharpened edge positioned towards a distal end of said torque device.6. The implant delivery system of claim 1 , wherein said first passage extends between a proximal and distal end of said torque device.7. The implant delivery system of claim 6 , wherein said first passage further extends through a clamp mechanism located near a proximal end of said torque device.8. The implant delivery system of claim 7 , wherein said first passage extends through a collet and screw member of said clamp mechanism.9. The implant delivery system of claim 1 , wherein said implant is an embolic ...

DEVICES, SYSTEMS, AND METHODS FOR ATRIAL APPENDAGE OCCLUSION USING LIGHT CURE

Atrial appendage occlusion devices and methods of using the same that employ the application of light having a desired wavelength range. The devices of the present disclosure comprise a telescoping catheter assembly coupled with an adhesive delivery device and a suction source, and comprise at least one optical fiber disposed therein. The catheter assembly is configured to isolate an atrial appendage cavity, deliver suction and adhesive thereto, and, using the optical fiber(s), cure the adhesive present within the cavity all without withdrawing any components of the catheter assembly from the body. Methods for using such device in the treatment of atrial appendage occlusion are also provided. 1. A device for occluding an atrial appendage of a heart and delivering light thereto , the device comprising:a tubular shaft sized and shaped for insertion into a heart, the shaft comprising a proximal end, an open distal end, and at least one lumen extending therebetween;a balloon coupled to the distal end of the shaft, the balloon configured for inflation and deflation;a patch removably coupled with the distal end of the shaft and disposed on the shaft independently of, and adjacent to the balloon and at a location distal of the balloon, the patch configured to occlude an ostium of an atrial appendage cavity when positioned thereover;a catheter sized and shaped for slidable insertion into the lumen of the shaft, the catheter comprising a proximal end, a distal end having at least one opening, and an interior extending between the proximal and distal ends thereof; andat least one optical fiber disposed within the interior of the catheter, each optical fiber configured to emit light having a range of wavelengths, wherein when light is emitted from the at least one optical fiber, the light is communicated through the at least one opening of the distal end of the catheter.2. The device of claim 1 , wherein the balloon comprises a disc-shaped configuration.3. The device of claim ...

MULTI-FUNCTIONAL OCCLUDER

The present invention is related to an occlusion device for occluding an opening in a body tissue and a method of deploying the said occlusion device to the site of defect. The construction of the occlusion device comprising two discs, that are centrally connected by a central portion and retention screws, is such that it offers the major advantage of haemodynamic adjustment providing a better-fit to the size of the defect. 1. A multi-functional occlusion device comprising of:a flexible proximal disc preferably a high-pressure disc and a flexible distal disc preferably a low-pressure disc;a septum;retention screws on the outer side of said proximal and distal discs; anda central geometrically shaped connector section;wherein the said proximal disc and distal disc are of uniform size, and straddle the said septum to provide stability on opposite sides of a defect; andthe said central geometrically shaped connector section is cone shaped, and provides hemodynamic adjustment of the said proximal disc and distal disc.2. The multi-functional occlusion device according to claim 1 , wherein the said proximal disc and distal disc function as high-pressure disc and low-pressure disc claim 1 , respectively claim 1 , in the ventricular and arterial sections wherein the pressure gradient is high.3. The multi-functional occlusion device according to claim 1 , wherein the retention screws present on the outer side of the said discs enable deployment through trans-venous (antegrade) or trans-arterial (retrograde) approach.4. The multi-functional occlusion device according to claim 1 , wherein the central geometrically shaped connector section connects the said proximal disc and distal disc to maintain the high-pressure disc in the high-pressure chamber of the heart and the low-pressure disc in the low-pressure chamber of the heart claim 1 , and provides hemodynamic adjustment.5. The multi-functional occlusion device according to and claim 1 , wherein the central geometrically ...

Advanced Endovascular Clip and Method of Using Same

Embodiments disclosed herein are directed towards an endovascular clip comprising a proximal anchoring member and a distal self-expanding member. The proximal anchoring member and distal self-expanding member are configured to extend across opposite sides of a neck of an aneurysm.

INTRA-ANEURYSM DEVICES

Devices for occluding an aneurysm are provided. In particular, the device include an upper member that sits against the dome of the aneurysm, a lower member that sits in the neck of the aneurysm, and a means of adjusting the overall dimensions of the device. Also provided are methods of making and using these devices. 1. A vaso-occlusive device for placement within an aneurysm having a neck and a sac , the device comprising:a plurality of inter-woven wires having a compressed delivery configuration for passage through a delivery catheter, and an expanded deployed configuration,wherein, when the device is positioned within the aneurysm in the expanded deployed configuration, the plurality of inter-woven wires are configured to bridge the neck of the aneurysm and occlude the aneurysm sac, respectively, andwherein, in the expanded deployed configuration, first ends of the wires form an external concavity in a first end portion of the device, and second ends of the wires form an external concavity in a second end portion of the device.2. The vaso-occlusive device of claim 1 , wherein in the expanded deployed configuration claim 1 , the plurality of inter-woven wires define a cylindrical middle body portion having a first end that transitions into the first end portion claim 1 , and a second end that transitions into the second end portion.3. The vaso-occlusive device of claim 1 , wherein in the expanded deployed configuration claim 1 , the plurality of inter-woven wires define a substantially spherical interior region.4. The vaso-occlusive device of claim 1 , wherein the device is self-expanding.5. The vaso-occlusive of claim 1 , further comprising a mechanical or electrolytic detachment junction.6. The vaso-occlusive device of claim 3 , wherein the detachment junction is disposed between the plurality of inter-woven wires and a pusher wire slidably disposed within a delivery catheter.7. The vaso-occlusive device of claim 1 , wherein the device is made from a ...

Methods and systems for endovascularly clipping and repairing lumen and tissue defects

An implantable closure structure is delivered using minimally invasive techniques and inhibits the migration of liquid and particulate matter from inside a physiological cavity or opening, such as an aneurysm or a septal defect, as well as inhibiting the flow of liquid and particulate matter, such as from an associated blood vessel or chamber, into the physiological cavity or opening. The device has a closure structure that covers the neck or opening of a cavity and has one or more anchoring structures for supporting and retaining the closure structure in place across the cavity or opening.

Intraluminal implant delivery system and method

Systems, devices, and methods for retracting a pull wire from a hypotube can include positioning a pull wire having an engagement bump on its proximal end within a channel of a device and sliding the pull wire proximally through a channel of a device by moving grippers of the device proximally to engage and slide the bump. Subsequent distal movement of the grippers can result in the grippers disengaging the bump without disturbing the position of the pull wire or causing the pull wire to move distally.

Selective Aortic Balloon Occlusion Device, Methods of Use, and Uses Thereof

A selective aortic balloon device includes a catheter comprising an open distal end configured to be inserted into a body cavity or vessel, and a plurality of adjustable port regions with inflatable balloons between adjacent adjustable port regions. Each adjustable port region is configured to move between a closed position and an open position to selectively allow fluid flow to enter the catheter through the open distal end and to exit the catheter through one or more of the plurality of adjustable port regions depending on an inflation pattern of the inflatable balloons. 1. A selective aortic balloon occlusion device comprising: a distal end configured to be inserted into a body cavity or vessel, the distal end having at least one opening;', 'a first balloon downstream of the distal end;', 'a first adjustable port region downstream of the first balloon;', 'a second balloon downstream of the first adjustable port region; and', 'a second adjustable port region downstream of the second balloon, the first adjustable port region and the second adjustable port region each configured to selectively individually move between an open position and a closed position, wherein:, 'a catheter comprisingthe open position allows flow into the distal end through the catheter and exiting through an opened adjustable port region; andthe closed position prevents flow through a closed adjustable port region.2. The selective aortic balloon occlusion device of claim 1 , wherein each of the first adjustable port region and the second adjustable port region comprises:an outer catheter tube having at least one outer aperture there through;an inner tube sized to movably fit within the outer catheter tube and having at least one inner aperture there through; anda biasing member attached to the inner tube, biasing the inner tube so that the at least one inner aperture and the at least one outer aperture are offset in the closed position, the biasing member configured to move the inner tube to ...

RAPID EXCHANGE CATHETERS AND EMBOLIC PROTECTION DEVICES

A catheter compiling a housing portion defining an interior cavity and the housing portion comprising a housing member having an interior space dimensioned for housing an indwelling medical device. The elongated member comprises a lumen extending at least from an exit port to a distal port, the housing member is disposed within the lumen, and the lumen is dimensioned in the housing portion to receive a guidewire outside of the interior space of the housing member. A medical device for filtering emboli from blood flowing in a blood vessel of patient comprising an elongate support member and an elongate side branch member connected to the elongate support member. The filter element is attached to the elongate side branch member by a proximal filter element slider, and the elongate side branch member is adapted to maintain the filter element centered in the vessel. 150-. (canceled)52. The system of claim 51 , wherein the housing member is secured at a fixed location within the housing portion.53. The system of claim 51 , wherein the housing member is configured to move axially within the housing portion.54. The system of claim 53 , wherein the housing portion comprises distal and proximal housing sections claim 53 , and wherein the housing member is configured to move axially between the proximal and distal sections of the housing portion.55. The system of claim 54 , wherein the proximal housing section comprises a stop member.56. The system of claim 55 , wherein the stop member defines one or more sidewall slots configured to define pathways for the guidewire.57. The system of claim 51 , wherein the housing portion and the distal portion have outer diameters and the outer diameter of the housing portion is larger than the outer diameter of the distal portion.58. The system of claim 51 , wherein the housing portion and the distal portion have inner diameters and the inner diameter of the housing portion is larger than the inner diameter of the distal portion.59. The ...

FLEXIBLE LOW COMPLIANCE EXTENSION TUBING FOR BALLOON INFLATION

A controlled volume inflation-deflation device to inflate a balloon to occlude a blood vessel by dialing a knob that locks at rotational positions to locate a plunger at equally spaced locations within a syringe of the inflation-deflation device. The inflation-deflation device includes a releasable latch to lock the proximal and distal housings together to hold the plunger forward for occlusion, and to separate and hold the proximal and distal housings to retract the plunger for perfusion. When the inflation-deflation device is returned to the latched position, the balloon is re-inflated to its previous occlusive diameter. Also, an extension tube made of a lower modulus outer material co-extruded over and miscible with a higher modulus inner material may be used to produce a suitably low compliance extension tube for the inflation-deflation device. The balloon may have tapered ends and a cylindrical center portion so that it increases by more equal increments in outer diameter in response to incremental equal increases in inflation volume. 1. A method comprising:advancing a catheter percutaneously through a blood vessel to a region of interest, the catheter having a proximal end, a distal end, and an exterior surface at or adjacent the distal end of the catheter axially coupled to a balloon;locating a plunger at a first location in a syringe tube having a fluid output coupled to a fluid input of the catheter; then a) rotating a knob of the syringe to push the plunger to a second location in the syringe tube to inflate the balloon to an inflation diameter;', 'b) reading a pressure display to determine a pressure in the syringe;', 'c) testing for occlusion of the blood vessel at the region of interest;, 'pushing a button to unlock the plunger position in the syringe tube; then'}if the occlusion is not attained, repeating a), b) and c) to attain occlusion; andperforming a treatment of the blood vessel at the region of interest.2. The method of claim 1 , wherein a) ...

Devices and methods for delivering vascular implants

Embodiments of the present disclosure are directed to delivery devices, methods, and systems for delivering an implant to a target site. In one embodiment, a delivery device includes a core member defining a proximal end and a distal end and an outer winding defining a proximal end and a distal end, wherein the outer winding surrounds and is coupled to the core member. The outer winding extends at least partially between the proximal end of the core member and the distal end of the core member, and the outer winding is configured for displacement within a delivery catheter. The delivery device further includes a coupling member at the distal end of the core member configured to releasably attach to an implant.

DETACHMENT MECHANISMS FOR IMPLANTABLE DEVICES

The present invention relates to detachment mechanisms for delivering and releasing implantable devices into a body lumen. According to certain aspects, systems of the invention include a junction that couples an implantable device to a delivery member. The junction includes an anodic portion and a cathodic portion galvanically coupled to the anodic portion such that the anodic portion corrodes when exposed to an electrolytic fluid, thereby detaching the implantable device from the delivery member without application of energy from an external power source. 1. A system for delivering an implantable device into a body lumen , the system comprisinga junction coupling an implantable device to a delivery member, the junction comprising an anodic portion and a first cathodic portion galvanically coupled to the anodic portion such that the anodic portion corrodes when exposed to an electrolytic fluid, thereby detaching the implantable device from the delivery member without application of energy from an external power source.2. The system of claim 1 , wherein the anodic portion is operably coupled to a distal portion of the delivery member claim 1 , a proximal portion of the implantable device claim 1 , or both.3. The system of claim 1 , wherein the anodic portion is a thin film or layer.4. The system of claim 1 , wherein the first cathodic portion is a tubular structure.5. The system of claim 1 , wherein the first cathodic portion forms an overlapping joint with one or more of the anodic portion claim 1 , a distal portion of the delivery member claim 1 , and a proximal portion of the implantable device.6. The system of claim 1 , wherein the junction further comprises a second cathodic portion.7. The system of claim 6 , wherein the first cathodic portion is operably coupled to a proximal portion of the implantable device and the second cathodic portion is operably coupled to a distal portion of the delivery member.8. The system of claim 6 , wherein the anodic portion is ...

Patulous eustachian tube stent

A system effectively narrows a patulous Eustachian tube (ET) of a patient with a guide catheter, instrument, and insert. The guide catheter includes a shaft, a lumen and a distal end configured to provide access the ET when the guide catheter is inserted into a head of the patient. The instrument comprises a shaft. The insert comprises a body configured to radially expand and retract between a non-expanded state and an expanded state. The insert is sized and shaped to be received within the first lumen when in the non-expanded state and is operable to expand to the expanded state to substantially reduce an effective diameter of the ET.

SYSTEMS AND METHODS FOR SUPPORTING OR OCCLUDING A PHYSIOLOGICAL OPENING OR CAVITY

Implantable devices for placement at a cavity or opening such as an aneurysm are disclosed. The implantable devices, in a deployed condition, have a generally inverted U-shaped profile with a curved or angled framework support structure sized and configured for placement in proximity to tissue surrounding the opening and anchoring legs extending proximally from the framework structure sized and configured to contact the wall of a neighboring lumen at opposed locations. Occlusive and semi-occlusive membranes may be associated with the framework support structure and deployed over the opening to provide exclusion of the opening and flow diversion. Proximal anchoring segments providing additional lumen wall surface area contact for the implantable device following deployment may be incorporated. 1. An implantable device configured for deployment from a generally small delivery condition to a larger diameter deployed condition at an opening of a physiological cavity , the implantable device comprising: a longitudinal centerline joining two lateral areas of the framework structure; and', 'and an axial centerline joining two end points of two axial areas of the framework structure;, 'a substantially planar, generally diamond-shaped framework structure configured for bending into an inverted U-shape for deployment, the generally diamond-shaped framework structure characterized bytwo or more anchoring legs connected to and extending from the generally diamond-shaped framework structure; andanchoring leg extensions connected to and extending from each of the two or more anchoring legs, the anchoring leg extensions each comprising a proximal junction configured for joining proximal ends the anchoring leg extensions.2. The implantable device of claim 1 , further comprising a membrane structure extending within the generally diamond-shaped framework structure claim 1 , and when deployed and positioned claim 1 , the membrane structure is configured to substantially cover across ...

METHODS FOR VAS-OCCLUSIVE CONTRACEPTION AND REVERSAL THEREOF

Disclosed are methods of delivering an agent to the lumen of the vas deferens under guidance of ultrasound imaging. The methods include vas-occlusive contraception in which the vas deferens is non-surgically isolated and an occlusive substance is percutaneously administered into the lumen of the vas deferens under ultrasound. Also disclosed are methods of reversal of vas-occlusive contraception and methods of delivering an agent to the lumen of the vas deferens. Also disclosed are compositions for use in the methods of the invention. 1. A composition comprising:one or more species with a diameter of 0.1 to 1 μm in solvent;wherein the one or more species are capable of forming an implantable network with pores with a diameter of less than or equal to 3 μm;wherein the one or more species and/or the implantable network are capable of being injected into a bodily lumen; andwherein the implantable network has a permanent lifespan in vivo.2. The composition of claim 1 , wherein one or more of the species comprises one or more of natural or synthetic monomers claim 1 , polymers claim 1 , copolymers or block copolymers claim 1 , biocompatible monomers claim 1 , polymers claim 1 , copolymers or block copolymers claim 1 , polystyrene claim 1 , neoprene claim 1 , polyetherether 10 ketone (PEEK) claim 1 , carbon reinforced PEEK claim 1 , polyphenylene claim 1 , polyetherketoneketone (PEKK) claim 1 , polyaryletherketone (PAEK) claim 1 , polyphenylsulphone claim 1 , polysulphone claim 1 , polyurethane claim 1 , polyethylene claim 1 , low-density polyethylene (LDPE) claim 1 , linear low-density polyethylene (LLDPE) claim 1 , high-density polyethylene (HDPE) claim 1 , polypropylene claim 1 , polyetherketoneetherketoneketone (PEKEKK) claim 1 , nylon claim 1 , fluoropolymers claim 1 , polytetrafluoroethylene (PTFE or TEFLON®) claim 1 , TEFLON® TFE (tetrafluoroethylene) claim 1 , polyethylene terephthalate (PET or PETE) claim 1 , TEFLON® FEP (fluorinated ethylene propylene) claim 1 , ...

Delivery device for vascular occluding device

A delivery device for delivering material into a catheter through a catheter port includes a cannula having a generally tubular shape and a distal end and a stability collet having a distal attachment portion configured to attach the stability collet to a catheter port. The stability collet has a longitudinal channel through which the cannula extends. The longitudinal channel is dimensioned to allow a longitudinal movement of the cannula in the longitudinal channel. The delivery device further includes an elastic member acting between the cannula and the stability collet. The elastic member biases the cannula distally relative to the stability collet. Thus, when the stability collet is attached to the catheter port, the cannula is urged toward the catheter port, thus reducing a risk of improper alignment between the cannula and the catheter port.

Occluder For Occluding An Atrial Appendage And Production Process Therefor

An occlusion device and a production process for it are described. The occlusion device consists of a mesh or braiding of at least one wire or thread wherein the occlusion device has been given a suitable design using a reshaping and/or heat-treatment process, is self-expandable, and is configured for secure anchoring in an atrial appendage of the left or right atrium of a heart. The occlusion device comprises a proximal retention region on a proximal end of the occlusion device a distal retention region and a central region between the proximal retention region and said distal retention region and wherein the occlusion device has a closed distal end without a holder, and wherein the occlusion device is at least partly of essentially spherical form, and hollow. 1. (canceled)2. A method of occluding an atrial appendage , comprising:advancing a distal end of a delivery device to a left atrial appendage;exposing an occlusion device within the left atrial appendage;allowing said occlusion device to self-expand to a distal first enlarged portion and a proximal second enlarged portion, wherein the first enlarged portion and the second enlarged portion are connected by a reduced-diameter region that has a smaller expanded diameter than said first enlarged portion and said second enlarged portion; and,allowing said first enlarged portion and said second enlarged portion to move, via said reduced-diameter region, relative to each other to thereby accommodate movements of a heart.3. The method of claim 2 , wherein said allowing said occlusion device to self-expand further comprises positioning said occlusion device such that at least a portion of said reduced diameter portion is spaced apart from a wall of said left atrial appendage and an interspace is created between said reduced diameter portion and said wall.4. The method of claim 2 , wherein said allowing said occlusion device to self-expand further comprises creating an interspace between tissue of said left atrial ...

INJECTABLE VALVE AND OTHER FLOW CONTROL ELEMENTS

Flow control elements can be injectably delivered through a needle (e.g., a fine hypodermic needle) or other tube and deployed into a blood vessel, percutaneously or laparoscopically, to effect the directional blood flow within the vessel. The valve (or other blood flow or occlusion control element) is delivered from outside the blood vessel directly to the chosen site within the blood vessel. The flow control elements are minimally invasive, reducing pain, discomfort and risk to the patient, while reducing the time the procedure takes to perform. In addition, the accuracy of deployment of the valve or other flow control element can be very precisely controlled. 1. Apparatus for controlling flow through a body lumen , the apparatus comprising: a resilient frame for seating against the inside wall of the body lumen and compressible for disposition within a tube for delivery through the side wall of the body lumen to the interior of the body lumen, the resilient frame having an opening therein; and', 'a flow restrictor in contact with the resilient frame for restricting flow through the opening of the resilient frame., 'an injectable flow control device for disposition within the body lumen, the injectable flow control device comprising2. Apparatus according to wherein the tube comprises a needle.3. Apparatus according to wherein the flow restrictor is formed integral with the resilient frame.4. Apparatus according to wherein the resilient frame comprises at least one anchor for securing the resilient frame to the side wall of the body lumen.5. Apparatus according to wherein at least one anchor extends through the side wall of the body lumen.6. Apparatus according to wherein at least one anchor comprises at least one laterally-extending element for disposition outside of the body lumen.7. Apparatus according to wherein at least two anchors extend through diametrically-opposed portions of the side wall of the body lumen.8. Apparatus according to wherein at least two ...

Implant, Medical Implant, And Method For Delivery Of A Medical Implant

An intravascular delivery device is disclosed comprising a delivery wire having a proximal and a distal end and an interior lumen extending there between and wherein said distal end comprises a connection interface adapted to matingly interlock with a proximal end portion of a medical implantable device, wherein said delivery device comprises a locking unit arranged to secure said connection interface in a locking position in which said medical implant is pivotably locked before a controlled release. 1. An intravascular delivery device comprising a delivery wire having a proximal and a distal end and an interior lumen extending there between and wherein said distal end comprises a connection interface adapted to matingly interlock with a proximal end portion of a medical implantable device , wherein said delivery device comprises a locking unit arranged to secure said connection interface in a longitudinal locking position relative a distal end of said delivery device , wherein said intravascular delivery device comprises a proximal portion having a resiliently flexible unit arranged to provide for flexibility in said locking position.2. The intravascular delivery device of claim 1 , wherein the resiliently flexible unit is a disc claim 1 , preferably made of rubber or silicone.3. The intravascular delivery device of claim 1 , wherein the locking unit has a proximal end providing a fitting area to the resiliently flexible unit claim 1 , and a preferably broadened proximal end in order to provide a proximally enlarged fitting area to the resiliently flexible unit.4. The intravascular delivery device claim 1 , wherein the resiliently flexible unit provides for flexibility of the delivery device when a holding structure of the intravascular delivery device is in a locking position.5. The intravascular delivery device of claim 4 , wherein claim 4 , in said locking position claim 4 , said medical implantable device is pivotably locked before a controlled release claim 4 ...

METHOD FOR INCREASING PACKING DENSITY OF EMBOLIZATION MATERIAL AND DETACHING EMBOLIZATION MATERIAL

Embodiments disclosed herein include an embolization material. The embolication material includes a tubular strand, with an outer surface, having a distal end and a proximal end, wherein the outer surface defines one or more slits. 1. A detacher for detaching embolization filler material having a flexible , annular , tubular configuration and an outer surface , with a proximal end and a distal end , comprising:a cannula, having an annulus, insertable into the proximal end of the embolization filler material annulus;a heat bond that bonds the cannula and embolization filler material to each other at the proximal end of the embolization filler material;a buttress tube positioned and slidable over the cannula and abutted against the surface of the embolization material;a rail wire positioned within the annulus of the cannula and advanced to the distal end of the embolization filler material;a locking knob attached to the buttress tube and engaging the cannula, wherein the cannula and buttress tube act as a pusher to move the embolization material through the delivery catheter into an embolization site.2. A delivery catheter for delivering the detacher of and embolization filler material to an aneurysm.3. The detacher of claim 1 , wherein the embolization filler material defines one of more slits on the outer surface.4. The detacher of claim 1 , wherein the cannula comprises an outer surface that is textured.5. The detacher of claim 1 , wherein the cannula comprises an outer surface is smooth.6. An embolization material comprising:a tubular strand, with an outer surface, having a distal end and a proximal end, wherein the outer surface defines one or more slits, wherein the slits are oblique to the outer surface of the tubular strand.7. The embolization material of claim 6 , wherein the distal end of the tubular strand comprises a bumper.8. An embolization material having a distal end and a proximal end claim 6 , wherein the outer surface defines one or more slits.9. ...