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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 2291. Отображено 100.
12-01-2012 дата публикации

Energy based devices and methods for treatment of patent foramen ovale

Номер: US20120010608A1
Автор: Dan Francis, Hanson S. Gifford, Iii, Jose Alejandro, Kenneth Horne, Mark E. Deem, William Malecki
Принадлежит: Terumo Corp

Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device fuirther include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

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Номер записи: 1
15-03-2012 дата публикации

Septal defect closure device

Номер: US20120065673A1
Автор: James F. McGuckin, Jr.
Принадлежит: Individual

A device for closing a septal defect of a patient comprising a covering member and at least one retaining leg. The covering member has a first configuration for delivery and a second configuration for placement on the first side of the defect. The at least one retaining leg is configured to contact tissue on the second side of the defect to retain the covering member and has a first configuration for delivery and a second configuration for placement on the second side of the defect.

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Номер записи: 2
04-10-2012 дата публикации

Apical puncture access and closure system

Номер: US20120253386A1
Автор: Ming Wu, Philip P. Corso, Jr., Ralph Schneider, Stanton J. Rowe
Принадлежит: Edwards Lifesciences Corp

A device, system, and method for providing access to, and sealing of, a body organ includes an implant device. An implant device has a main body having an internal access lumen, with a plurality of prongs extending from a distal end of the main body. The main body can include two lumens, one slidable within the other, to form a single continuous lumen with an adjustable length. The main body has an expanded configuration with an expanded diameter, and an unexpanded configuration with an unexpanded diameter. The prongs have a generally straight configuration where they extend distally of the distal end of the main body, and a bent configuration where the prongs bend around so that their tips extend proximally of the distal end of the main body. The device may include a hemostatic barrier to prevent fluid leakage therethrough when the main body is in the unexpanded configuration.

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Номер записи: 3
11-10-2012 дата публикации

Apparatus and methods to create and maintain an intra-atrial pressure relief opening

Номер: US20120259263A1
Автор: David Celermajer, Edward McNamara, Hiroatsu Sugimoto, Michael W. Sutherland
Принадлежит: DC Devices Inc

The present disclosure relates to a method and a device for treating heart failure by normalizing elevated blood pressure in the left and right atria of a heart of a mammal The present disclosure includes methods for creating and maintaining an opening in the atrial septum. Tools for making an opening and enlarging the opening are also disclosed. Use of the techniques and tools described herein prolongs the patency of an intra-atrial pressure relief opening.

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Номер записи: 4
15-11-2012 дата публикации

Intra-atrial implants made of non-braided material

Номер: US20120290062A1
Автор: David Celermajer, Edward McNamara, Hiroatsu Sugimoto, Stephen Forcucci
Принадлежит: Individual

Several unique intra-cardiac pressure devices, placement catheters, methods of placement and methods of treating heart failure are presented. The intra-cardiac pressure devices presented allow sufficient flow from the left atrium to the right atrium to enable the relief of elevated left atrial pressure and resulting patient symptoms. The intra-cardiac pressure devices are made of a non-braided material.

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Номер записи: 5
31-01-2013 дата публикации

Occlusion device for closing anatomical defects

Номер: US20130030455A1
Автор: Hong Duc Duong, Venkatraman Subramanian, Wei Luen James Yip, Yin Chiang Freddy Boey, Yong-dan Tang
Принадлежит: NANYANG TECHNOLOGICAL UNIVERSITY

The present invention generally relates to the field of transcatheter device closure techniques for closing an opening in a tissue and more particularly, to occlusion devices for closing anatomical defects in tissue. More particularly the present invention refers to occlusion devices for closing septal abnormalities such as atrial septal defects and patent foramen ovale, and to methods of closing an anatomical defect in a tissue.

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Номер записи: 6
25-07-2013 дата публикации

Closure device

Номер: US20130190810A1
Автор: Ian J. Clark, Kelly J. McCrystle, Laveille K. Voss, Ni Ding, Wouter E. Roorda
Принадлежит: Abbott Vascular Inc

A device for closing an opening in a wall of a body lumen includes a closure element with a first flange and a second flange. Both the first flange and the second flange may have a delivery cross-sectional dimension and a deployed cross-sectional dimension. The device for closing an opening further includes a first coupler element disposed on the first flange and a second coupler element disposed on the second flange, the first and second coupler elements cooperating to couple the first flange to the second flange.

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Номер записи: 7
26-09-2013 дата публикации

Device with Biological Tissue Scaffold for Percutaneous Closure of an Intracardiac Defect and Methods Thereof

Номер: US20130253538A1
Автор: Carol A. Devellian, Robert M. Carr
Принадлежит: WL Gore and Associates Inc

The invention provides an intracardiac occluder, which has biological tissue scaffolds as occlusion shells, for the percutaneous transluminal treatment of an intracardiac defect. The intracardiac occluder includes a proximal support structure supporting the proximal occlusion shell and a distal support structure supporting the distal occlusion shell. In one embodiment, biological tissue derived from the tunica submucosa layer of the porcine small intestine forms the occlusion shells.

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Номер записи: 8
17-10-2013 дата публикации

Devices and methods for delivering implants for percutaneous perforation closure

Номер: US20130274795A1
Автор: Bartosz PAWLIKOWSKI, Christopher Martin, Damien Ryan, Des Regan, Ger Brett, Joseph DOLPHIN, Mark MCGOLDRICK, Matthew Murphy, Michael Dunning, Michael MCCARTIN, Micheál Hession, Peter Grant
Принадлежит: VIVASURE MEDICAL Ltd

A device for delivering an implant configured to seal an aperture in a tissue includes: a delivery shaft configured to engage the implant to allow the implant to be maneuvered into sealing engagement with a distal surface of the tissue, the delivery shaft comprising a retaining sleeve comprising a locking projection engagable with a locking recess of the implant to secure the implant to the delivery shaft, and a release sleeve axially slideable relative to the retaining sleeve between a first axial position in which the release sleeve is configured to maintain locking engagement between the locking recess and the locking projection, and a second axial position in which the release sleeve permits the locking projection to disengage the locking recess.

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Номер записи: 9
07-11-2013 дата публикации

Tubular Patent Foramen Ovale (PFO) Closure Device with Catch System

Номер: US20130296925A1
Автор: Andrzej J. CHANDUSZKO, David J. Callaghan
Принадлежит: WL Gore and Associates Inc

The present invention provides a device for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO). The occluder includes two sides connected by a central tube. The occluder is formed from a tube, which is cut to produce struts in each side. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. In some embodiments, at least one of the sides includes a tissue scaffold. The occluder further includes a catch system that maintains its deployed state in vivo. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system is deployed so that the occluder exerts a compressive force on the septal tissue and closes the aperture.

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Номер записи: 10
28-11-2013 дата публикации

Single plane tissue repair patch having a locating structure

Номер: US20130317527A1
Автор: Gabriel R. Jacinto, Michael Cardinale
Принадлежит: Ethicon Inc

A novel single plane tissue repair patch is disclosed. The patch has a base member with an opening therethrough, and a closure member associated with the opening. Mounted to the periphery of the bottom side of the base member is a locating structure. The mesh may be used in open surgical procedures for hernia repairs and other repairs of body wall defects.

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Номер записи: 11
19-12-2013 дата публикации

Therapeutic methods and devices following myocardial infarction

Номер: US20130338695A1
Автор: Alexander Khairkhahan, Serjan D. Nikolic
Принадлежит: CardioKinetix Inc

Described herein are methods of treating a patient to prevent or correct cardiac remodeling following myocardial infarction. In general these methods may include inserting or implanting a device in a heart chamber to support the affected region within 72 hours after myocardial infarction. The device may be a support device (e.g., a resilient frame) and/or a partitioning device.

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Номер записи: 12
16-01-2014 дата публикации

Percutaneous perforation closure systems, devices, and methods

Номер: US20140018847A1
Автор: Bartosz PAWLIKOWSKI, Christopher Martin, Damien Ryan, Des Regan, Ger Brett, Joseph DOLPHIN, Mark MCGOLDRICK, Matthew Murphy, Michael Dunning, Michael MCCARTIN, Micheál Hession, Peter Grant
Принадлежит: VIVASURE MEDICAL Ltd

A device for sealing an aperture in a tissue includes: an implant configured to seal the aperture when positioned adjacent to the aperture; and a delivery shaft configured to engage the implant to allow the implant to be maneuvered into sealing engagement with a distal surface of the tissue, the delivery shaft comprising a retaining sleeve comprising a locking projection engagable with the locking recess of the implant to secure the implant to the delivery shaft, and a release sleeve axially slideable relative to the retaining sleeve between a first axial position in which the release sleeve is configured to maintain locking engagement between the locking recess and the locking projection, and a second axial position in which the release sleeve permits the locking projection to disengage the locking recess.

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Номер записи: 13
06-03-2014 дата публикации

Closure device

Номер: US20140066980A1
Автор: Dusan Pavcnik, Kurt J. Tekulve, Michael Deckard
Принадлежит: Cook Medical Technologies LLC, Oregon Health Science University

A closure device for closing a bodily passageway is provided. The device includes first and second frames and first and second crossbars. A sheet of biocompatible material is attached to one or more of the frames. The first crossbar extends across the first frame and has terminal crossbar ends connectively linked to separate sites on the first frame; the second crossbar is similarly linked to the second frame. The crossbars are attached to each other at a connection point, and they are each configured to bend away from the connection point when the closure device is deployed to close a bodily passageway. A method of making the closure device is provided, as well as a method for closing a bodily passageway using such a device. Further, a closure device assembly is provided, including a closure device, a delivery catheter housing, and a delivery release member.

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Номер записи: 14
03-04-2014 дата публикации

Vascular closure device with a plug having a variable expansion rate and method for using the same

Номер: US20140094846A1
Автор: Jyueboon Lim
Принадлежит: St Jude Medical Puerto Rico LLC

A vascular closure device, having an insertion sheath and a vascular closure implant positioned at least partially in the insertion sheath. The vascular closure implant may have an anchor element, the anchor element including an expandable material, a first puncture contact portion, a bend portion connected to the first puncture contact portion, the bend portion including a bend, and a second puncture contact portion connected to the bend portion. The vascular closure implant may also include a plug element coupled to the bend portion of the anchor element. The anchor element may be formed of an expandable material having the same or a different expansion rate than a material forming the plug element. The vascular closure device may additionally include a locator tube having a vessel locator positioned at least partially in the locator tube. The vessel locator may also have an elongated member that includes a superelastic material.

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Номер записи: 15
10-04-2014 дата публикации

System and method for transapical access and closure

Номер: US20140100594A1
Автор: Alan E. Shluzas, Frank Litvack, Gary Steese-Bradley, John F. Shanley, Stephen H. Diaz
Принадлежит: ENTOURAGE MEDICAL TECHNOLOGIES Inc

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

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Номер записи: 16
06-01-2022 дата публикации

ADHESION PROMOTION DEVICE

Номер: US20220000483A1
Автор: ARAMAKI Naoki, Kai Miho, SUZUKI Miria
Принадлежит: TERUMO KABUSHIKI KAISHA

An adhesion promotion device is disclosed, which is capable of reducing risk factors of an anastomotic leakage after surgery. The adhesion promotion device includes a sheet-shaped first region disposed between one joint target site and the other joint target site of biological organs to promote adhesion of a biological tissue, a second region provided inward of the first region and separated from the first region in a direction intersecting with a surface direction of the first region, and an interlock portion that interlocks the first region and the second region with each other. 1. An adhesion promotion device , the adhesion promotion device comprising:a main body portion disposed between biological organs serving as a joint object; andwherein the main body portion includes a sheet-shaped first region disposed between one joint target site and the other joint target site of the biological organs to promote adhesion of a biological tissue, a second region provided inward of the first region and separated from the first region in a direction intersecting with a surface direction of the first region, and an interlock portion that interlocks the first region and the second region with each other.2. The adhesion promotion device according to claim 1 , wherein the interlock portion has a cross-sectional shape which is narrowed from the first region side toward the second region side.3. The adhesion promotion device according to claim 1 , wherein the interlock portion has a cross-sectional shape which is widened from the first region side toward the second region side.4. The adhesion promotion device according to claim 1 , wherein the interlock portion has a cross-sectional shape orthogonal to the surface direction of the first region.5. The adhesion promotion device according to claim 1 , wherein the first region is joined to the biological tissue by a joining device including a first engagement instrument disposed in one joint target site of the biological organs claim ...

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Номер записи: 17
04-01-2018 дата публикации

Vascular hole closure device

Номер: US20180000471A1
Автор: James F. McGuckin, Jr., James S. Tarmin, Thanu Anidharan
Принадлежит: Rex Medical LP

A device for closing an aperture in a vessel wall, the aperture having an external opening in an external region of the vessel wall and an internal opening in an internal region of the vessel wall. The device includes a covering member positionable inside the vessel against the internal opening of the aperture and having a dimension to prevent egress of fluid through the aperture. A securing member is positionable external of the vessel and has a plurality of pores extending therethrough. A flexible connecting member operatively connects the covering member and securing member and moves the securing member toward the covering member.

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Номер записи: 18
13-01-2022 дата публикации

DEVICES AND METHODS FOR OCCLUSION OF VASCULAR SYSTEM ABNORMALITIES

Номер: US20220008050A1
Автор: Morin Kristen, Samaray Andrey, Springer Trevor
Принадлежит:

Described herein is a medical device for treating a target site, the medical device including, a proximal end including a disc and a distal end including a lobe. The disc and the lobe are connected by a connecting member. The lobe includes a proximal portion defining a proximal surface of the lobe, a distal portion defining a distal surface of the lobe, and a middle portion connecting and extending between the proximal portion and the distal portion. A first transition between the proximal portion and the middle portion is curved, and a second transition between the middle portion and the distal portion is curved. The medical device also includes a plurality of stabilizing wires coupled to the lobe at a radially outer surface of the middle portion, each stabilizing wire including a hook portion extending radially outward from the at least one lobe. 1. A medical device for treating a target site , the medical device comprising:a proximal and a distal end, wherein the proximal end comprises a disc and the distal end comprises a lobe, wherein the disc and the lobe are connected by a connecting member, wherein the lobe comprises a proximal portion defining a proximal surface of the lobe, a distal portion defining a distal surface of the lobe, and a middle portion connecting and extending between the proximal portion and the distal portion, wherein a first transition between the proximal portion and the middle portion is curved and a second transition between the middle portion and the distal portion is curved, wherein the lobe has an expanded configuration when deployed at the target site and a reduced configuration for delivery to the target site; anda plurality of stabilizing wires coupled to the lobe at a radially outer surface of the middle portion, each stabilizing wire comprising a hook portion extending radially outward from the lobe.2. The medical device of claim 1 , wherein the medical device is formed from a shape-memory material.3. The medical device of claim ...

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Номер записи: 19
13-01-2022 дата публикации

PATENT FORAMEN OVALE (PFO) TUNNEL FILLER

Номер: US20220008051A1
Автор: Cornelius Linda, Dale Theodore P., Eidenschink Tracee
Принадлежит:

A patent foramen ovale (PFO) tunnel filler medical device including device anchors coupled to and extending outwardly from a filler portion of a device frame that has a generally planar shape configured to fill a PFO tunnel, and a delivery system including the same are described herein. The medical device includes a fabric layer and the device anchors are configured to extend outwardly from the device frame. 1. A medical device for treating a patent foramen ovale (PFO) target site , the medical device comprising:a device frame having a generally planar shape configured to fill a PFO tunnel and formed from a shape memory material, wherein the device frame comprises a filler portion; andat least one fabric layer covering the filler portion of the device frame.2. The medical device of claim 1 , wherein the shape memory material is selected from nitinol and MP35.3. The medical device of claim 1 , wherein the shape memory material comprises a polymer.4. The medical device of claim 1 , wherein the fabric layer comprises at least one of metal fabric claim 1 , polymer fabric claim 1 , metal mesh claim 1 , polymer mesh claim 1 , braided wire claim 1 , woven wire claim 1 , braided polymer claim 1 , woven polymer claim 1 , nonwoven polymer claim 1 , and combinations thereof.5. The medical device of claim 1 , further comprising a plurality of device anchors extending outwardly from the filler portion and coupled to at least one of the device frame and the at least one fabric layer.6. The medical device of claim 5 , wherein each of the plurality of device anchors is one of a knurl claim 5 , a knot claim 5 , and a loop formed from the fabric layer.7. The medical device of claim 5 , further comprising at least one channel formed within the fabric layer claim 5 , and wherein each of the plurality of device anchors extends out of the at least one channel.8. The medical device of claim 5 , wherein the plurality of device anchors comprises a plurality of hooks.9. The medical device of ...

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Номер записи: 20
13-01-2022 дата публикации

Medical Device

Номер: US20220008074A1
Автор: ARAMAKI Naoki, Fujii Anri, Kai Miho, Uchitomi Kensuke
Принадлежит: TERUMO KABUSHIKI KAISHA

A medical device is disclosed capable of reducing risk factors of an anastomotic leakage after a surgical operation is performed. The medical device includes an adhesion promotion sheet configured to include an adhesion promotion portion promoting adhesion of biological tissues and a frame portion provided outside the adhesion promotion portion in a plane direction and a pulling unit connected to the adhesion promotion sheet and configured to deform a second region so as to cover at least a portion of an outer peripheral surface of a biological organ to be joined with a pulling operation. 1. A medical device comprising:an adhesion promotion sheet including a first region that promotes adhesion of biological tissues and a second region provided outside the first region in a plane direction; anda pulling unit connected to the adhesion promotion sheet and configured to deform the second region so as to cover at least a portion of an outer peripheral surface of a biological organ to be joined with a pulling operation.2. The medical device according to claim 1 , wherein the pulling unit includes a connection section connected to the second region and a non-connection section claim 1 , the non-connection section is not connected to the second region and is configured to be pulled out of the adhesion promotion sheet.3. The medical device according to claim 2 , wherein the connection section is connected to the second region with a length equal to or more than half the adhesion promotion sheet along a circumferential direction.4. The medical device according to claim 2 , wherein at least a portion of the connection section has a rigidity greater than a rigidity of the non-connection section.5. The medical device according to claim 1 , wherein the pulling unit includes a string-shaped member.6. The medical device according to claim 5 , wherein the pulling unit includes a strip-shaped member having a predetermined length claim 5 , the strip-shaped member strip-shaped having a ...

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Номер записи: 21
01-01-2015 дата публикации

Space filling devices

Номер: US20150005810A1
Автор: Aaron L. PARIS, Brandon A. Lurie, Charles J. Center, Cody L. Hartman, Edward H. Cully, Nathan K. Mooney, Nathan L. Friedman, Nichlas L. HELDER, Roark N. Wolfe, Steven J. Masters, Thomas R. McDaniel
Принадлежит: WL Gore and Associates Inc

An occlusive device includes a covering component configured to modulate passage of blood or thrombus therethrough, and an occlusion frame that includes a plurality of elongate occlusion frame members. The elongate occlusion frame members are arranged to form a generally disc-shaped member. The occlusion frame is at least partially covered by the covering component. The device further includes an anchor frame that includes a plurality of elongate anchor frame members. The device further includes a first hub component from which the elongate frame members extend, and a second hub component from which the elongate frame members extend.

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Номер записи: 22
20-01-2022 дата публикации

INTERATRIAL SHUNTS HAVING BIODEGRADABLE MATERIAL, AND METHODS OF MAKING AND USING SAME

Номер: US20220015897A1
Автор: EIGLER Neal, Nitzan Yaacov, ROZENFELD Erez, Whiting James S., Yacoby Menashe
Принадлежит: V-WAVE LTD.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. 1. A device for regulating blood flow in a patient to treat a condition , the device comprising:a stent comprising a first flared end region, a second flared end region, a neck region disposed between the first and second flared end regions, and a passageway extending through the first flared end region through the neck region and through the second flared end region, the stent configured to shunt blood between body cavities;a biocompatible material disposed on the stent to define a sheath that channels blood flow through the passageway; anda biodegradable material disposed on an inner surface of the biocompatible material at the neck region, the biodegradable material configured to inhibit tissue overgrowth across the biodegradable material within the passageway of the stent.2. The device of claim 1 , wherein the stent comprises a plurality of rings interconnected by a plurality of longitudinally extending struts.3. The device of claim 1 , wherein the biocompatible material is disposed in the neck region claim 1 , the second flared end region claim 1 , and a portion of the first flared end region of the stent.4. The device of claim 1 , wherein the ...

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Номер записи: 23
12-01-2017 дата публикации

SEALING DEVICE AND DELIVERY SYSTEM

Номер: US20170007221A1
Автор: Aurilia Brad D., Masters Steven J.
Принадлежит:

The invention relates to a sealing device for repair of cardiac and vascular defects or tissue opening such as a patent foramen ovale (PFO) or shunt in the heart, the vascular system, etc. and particularly provides an occluder device and trans-catheter occluder delivery system. The sealing device would have improved conformity to heart anatomy and be easily deployed, repositioned, and retrieved at the opening site. 1. A method of delivering a medical device to a delivery site within a patient , the method comprising:releasably coupling a medical device with a deployment handle, the medical device including an expandable frame having a plurality of struts extending from a proximal end to a distal end of the frame;arranging the medical device into an elongated configuration with the deployment handle by actuating a linear actuator within a slot to a proximal stopping position;arranging the medical device into a deployed configuration by actuating the linear actuator within the slot to a distal stopping position subsequent to actuating the linear actuator to the proximal stopping position.2. The method of claim 1 , further comprising actuating a release actuator to release the medical device from the deployment handle.3. The method of claim 1 , wherein arranging the medical device into the elongated configuration includes withdrawing the medical device within a catheter lumen of the deployment handle.4. The method of claim 1 , wherein the expandable frame comprises a proximal central frame portion claim 1 , and releasably coupling the medical device to the deployment handle includes coupling the proximal central frame portion to the deployment handle.5. The method of claim 1 , further comprising moving the at least one linear actuator laterally from a distal notch of the slot prior to withdrawing the at least one linear actuator proximally within the slot.6. The method of claim 1 , wherein the proximal stopping position is indicative of the medical device being ...

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Номер записи: 24
12-01-2017 дата публикации

SEALING DEVICE AND DELIVERY SYSTEM

Номер: US20170007222A1
Автор: Van Orden Brad W.
Принадлежит:

The invention relates to a sealing device for repair of cardiac and vascular defects or tissue opening such as a patent foramen ovale (PFO) or shunt in the heart, the vascular system, etc. and particularly provides an occluder device and trans-catheter occluder delivery system. The sealing device would have improved conformity to heart anatomy and be easily deployed, repositioned, and retrieved at the opening site. 110.-. (canceled)11. A deployment handle system comprising: a housing,', 'a slot having a length and arranged along at least a partial length of the housing, and', 'at least one linear actuator configured to move within the slot along the length thereof to transition the medical device between stages of deployment based on a position of the at least one linear actuator within the slot., 'a medical device configured to releasably couple to a deployment handle for delivery thereof, the deployment handle including12. The system of claim 11 , wherein the medical device comprises an expandable frame having a plurality of struts extending from a proximal end to a distal end of the frame.13. The system of claim 12 , wherein the proximal end of the expandable frame comprises a central frame portion configured to couple the medical device to the deployment handle.14. The system of claim 12 , wherein the expandable frame comprises a shape memory alloy configured to self-expand upon release from the deployment handle.15. The system of claim 11 , wherein the deployment handle further includes a release actuator configured to release the medical device from the deployment handle.16. The system of claim 11 , wherein the stages of deployment include: an elongated configuration of the medical device and a deployed configuration of the medical device.17. The system of claim 16 , wherein the at least one linear actuator is configured to elongate the medical device to the elongated configuration in response to withdrawing the at least one linear actuator proximally within ...

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Номер записи: 25
12-01-2017 дата публикации

FLANGED OCCLUSION DEVICES AND METHODS

Номер: US20170007262A1
Автор: Amplatz Kurt, Gu Xiaoping, Russo Pat, Santer Jana, Thill Gary A.
Принадлежит:

Implantable occlusion devices that include one or more flanges extending from a tubular body are disclosed. The flange or flanges may assist in retention of the device within a vessel, cavity, appendage, etc. At least one flange on the occlusion device may include a concave surface proximate one end of a body. Because of the shape of the flange, e.g., its concavity, the occlusion device may resist dislocation due to e.g., the forces generated within the left atrial appendage during atrial filbrillation. 117-. (canceled)18. A medical device for deployment in a body , wherein the device comprises:a tubular body comprising a first end and a second end, the body defining a longitudinal axis extending between the first end and the second end, the body comprising a body width measured transverse to the longitudinal axis when the device is in a relaxed configuration; andonly one flange attached to the body proximate the second end of the body, the only one flange comprising a flange width transverse to the longitudinal axis and a concave outer surface facing the first end of the body when the device is in the relaxed configuration,wherein the width of the body proximate the only one flange is less than the width of the flange when the device is in the relaxed configuration.19. The medical device of claim 18 , wherein the concave outer surface is linear in one or more directions.20. The medical device of claim 18 , wherein the concave outer surface is formed from a plurality of flat surfaces joined together.21. The medical device of claim 18 , wherein the flange comprises a convex outer surface facing the second end of the body.22. The medical device of claim 21 , wherein the convex surface faces away from the first end of the body when the device is in the relaxed configuration.23. The medical device of claim 18 , wherein the device comprises a collapsed configuration in which a distance between the first end and the second end is increased such that the body width and the ...

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Номер записи: 26
11-01-2018 дата публикации

Devices and methods for closure of transvascular or transcameral access ports

Номер: US20180008248A1
Автор: Koosha RAFIEE, Nasser Rafiee, Rany Busold, Robert J. Lederman, Stuart MacDonald, Toby Rogers
Принадлежит: Transmural Systems Llc, US Department of Health and Human Services

The present disclosure provides a variety of prostheses, delivery systems and techniques to facilitate closure of transvascular or transcameral access ports. Various embodiments of prostheses are provided including a plurality of radially expandable discs that can be filled with material to facilitate coagulation and to reduce or stop leakage from punctures in vessel walls.

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Номер записи: 27
11-01-2018 дата публикации

BIO-ABSORBABLE WOUND CLOSURE DEVICE AND METHOD

Номер: US20180008249A1
Автор: Taylor David M.
Принадлежит: EDWARDS LIFESCIENCES CORPORATION

A wound closure device comprises a first frame and a flexible tubular section connected to the first frame, the first frame implantable through a wound in a patient's skin into a lumen of a blood vessel with a portion of the tubular section extending out through the skin. The tubular section has a first portion and a second portion, a wall of the tubular section defining a coaxial inner bore. Twisting the first portion relative to the second portion of the tubular section closes the bore is closed in an area of the tubular section between the first and second portions, thereby closing the wound. Also disclosed is an embodiment for closing an opening in a heart, as well as a delivery device, systems, and methods. 1. A device for closing a wound , the device comprising an implant having a first end , a second end , and a longitudinal axis extending between the first end and the second end , the implant comprising:a first frame at the first end; anda flexible tubular section connected to the first frame and extending along the longitudinal axis, the tubular section having a first portion and a second portion;wherein a wall of the tubular section defines a coaxial inner bore, and wherein the device is adjustable to a first position where the first portion and the second portion of the tubular section are rotated circumferentially around the longitudinal axis in a first direction relative to one another, such that the bore is closed in an area of the tubular section between the first and second portions.2. The device of claim 1 , wherein the device is adjustable to a second position where the first portion and the second portion of the tubular section are rotated circumferentially in a direction opposite to the first direction relative to one another claim 1 , such that the bore is open between the first and second portions claim 1 , and wherein a length of the implant from the first end to the second end is longer in the second position than in the first position.3. The ...

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Номер записи: 28
14-01-2021 дата публикации

SEALING DEVICE AND DELIVERY SYSTEM

Номер: US20210007725A1
Автор: Masters Steven J.
Принадлежит:

The invention relates to a sealing device for repair of cardiac and vascular defects or tissue opening such as a patent foramen ovale (PFO) or shunt in the heart, the vascular system, etc. and particularly provides an occluder device and trans-catheter occluder delivery system. The sealing device would have improved conformity to heart anatomy and be easily deployed, repositioned, and retrieved at the opening site. 1. A medical device having a first end element , a second end element , and a longitudinal axis extending between the first end element and the second end element , the medical device comprising:a frame that includes a plurality of elongate elements that each extends the first end element to the second end element; a first disk adjacent the first end element including a first plurality of petals concentrically overlapping one another when viewed in a direction along the longitudinal axis in a deployed configuration, and', 'a second disk adjacent the second end element including a second plurality of petals concentrically overlapping one another when viewed in a direction along the longitudinal axis in the deployed configuration., 'a sealing member attached to the frame, the plurality of elongate elements and the sealing member forming2. The medical device of claim 1 , wherein an adjacent pair of petals of the first plurality of petals form overlapping zones between the adjacent pair of petals of the first plurality of petals that include two layers of the sealing member and an adjacent pair of petals of the second plurality of petals form overlapping zones between the adjacent pair of petals of the second plurality of petals that include two layers of the sealing member.3. The medical device of claim 1 , wherein each of the first plurality of petals includes a first portion claim 1 , a second portion claim 1 , and a third portion with the second portion being arranged between the first portion and the third portion claim 1 , and the first portion of each ...

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Номер записи: 29
10-01-2019 дата публикации

Left atrial appendage occluder

Номер: US20190008495A1
Автор: Anning Li
Принадлежит: Lifetech Scientific Shenzhen Co Ltd

A left atrial appendage occluder, including a closure disc , a bracket located on one side of the closure disc, and a connecting member connecting the closure disc and the bracket; the bracket includes a first fixing connection member, a second fixing connection member, and a number of support rods; the first ends of the plurality of support rods are collapsed and secured by the first fixing connection member; the second ends of the plurality of support rods are collapsed and secured by the second fixing connection member; a connecting member is connected to the first fixing connection member. The bracket is arranged such that the two ends constituted by at least two support rods have a closed structure, thus increasing the area of contact between the outer surface of the bracket and the left atrial appendage.

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Номер записи: 30
27-01-2022 дата публикации

IMPLANTABLE SEALABLE MEMBER WITH MESH LAYER

Номер: US20220022855A1
Автор: Barrett Noelle, Brett Gerard, Grant Peter, Martin Christopher, McGoldrick Mark, Pawlikowski Bartosz
Принадлежит:

The provided technologies provide an implant closure device having a mesh layer formed on a flexible substrate, collectively forming a sealable member, that improves a seal formed over an aperture in a body lumen. The mesh facilitates a faster and more secure adherence of the sealable member to the surrounding edges at the puncture site. Furthermore, the provided technology may promote platelet-capture and encourage localized platelet aggregation at the exposed collagen in the wound edges on the mesh layer. The platelet impregnated mesh layer can facilitate cellular adhesion, enabling the sealable member that is local to the wound opening to act, in essence, as a “biological glue.” 1. An implantable device for sealing an aperture in a tissue of a body lumen , the implantable device comprising: a flexible substrate; and', 'a mesh layer on the flexible substrate;, 'a sealable member, comprising'}wherein, when the implantable device is an a sealing position, the sealable member is disposed against an internal surface of the tissue adjacent to the aperture such that the mesh layer is in contact with the internal surface.2. The implantable device of claim 1 , wherein the flexible substrate comprises an extruded layer comprising a thickness in a range from about 5 μm and about 4000 μm.3. The implantable device of claim 2 , wherein the extruded layer comprises a thickness in a range from about 60 μm and about 120 μm.4. The implantable device of claim 1 , wherein the sealable member comprises a bioabsorbable polymer film claim 1 , wherein the bioabsorbable polymer film claim 1 , when introduced into cells claim 1 , is broken down by cellular machinery.5. The implantable device of claim 4 , wherein the bioabsorbable polymer film is broken down via enzymatic degradation.6. The implantable device of claim 4 , wherein bioabsorbable polymer film is broken down via hydrolysis.7. The implantable device of claim 4 , wherein the cells either reuse claim 4 , reabsorb claim 4 , or ...

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Номер записи: 31
10-01-2019 дата публикации

THROMBUS ASPIRATION WITH DIFFERENT INTENSITY LEVELS

Номер: US20190008626A1
Автор: Janardhan Vallabh, Janardhan Vikram
Принадлежит:

Vascular treatment devices and methods include a woven structure including a plurality of bulbs that may be self-expanding, a hypotube, for example including interspersed patterns of longitudinally spaced rows of kerfs, and a bonding zone between the woven structure and the hypotube. The woven structure may include patterns of radiopaque filaments measureable under x-ray. Structures may be heat treated to include various shapes at different temperatures. The woven structure may be deployable to implant in a vessel. A catheter may include a hypotube including interspersed patterns of longitudinally spaced rows of kerfs and optionally a balloon. Laser cutting systems may include fluid flow systems. 1. A system for facilitating aspiration of a thrombus in a vessel , the system comprising:an automated motor pump configured to facilitate aspiration of the thrombus, the automated motor pump comprising an external control panel configured to receive input from an operator; andpower electronics configured to power and control the automated motor pump to generate a plurality of suction patterns having a plurality of intensity levels, a first intensity level having a first negative pressure between 100 and 350 mm Hg;', 'a second intensity level having a second negative pressure between 351 and 550 mm Hg; and', 'a third intensity level having a third negative pressure between 551 and 769 mm Hg; and, 'wherein the plurality of intensity levels compriseswherein a first crescendo suction pattern of the plurality of suction patterns comprises a repetitive cycle comprising the first intensity level for a first duration, the second intensity level for a second duration after the first duration, and the third intensity level for a third duration after the second duration.2. The system of :wherein the first duration, the second duration, and the third duration are each between 1 and 30 seconds; andwherein a total duration of the repetitive cycle of the first crescendo suction pattern ...

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Номер записи: 32
10-01-2019 дата публикации

THROMBUS ASPIRATION USING AN OPERATOR-SELECTABLE SUCTION PATTERN

Номер: US20190008627A1
Автор: Janardhan Vallabh, Janardhan Vikram
Принадлежит:

Vascular treatment devices and methods include a woven structure including a plurality of bulbs that may be self-expanding, a hypotube, for example including interspersed patterns of longitudinally spaced rows of kerfs, and a bonding zone between the woven structure and the hypotube. The woven structure may include patterns of radiopaque filaments measureable under x-ray. Structures may be heat treated to include various shapes at different temperatures. The woven structure may be deployable to implant in a vessel. A catheter may include a hypotube including interspersed patterns of longitudinally spaced rows of kerfs and optionally a balloon. Laser cutting systems may include fluid flow systems. 1. A system for facilitating aspiration of a thrombus in a vessel using an operator-selectable suction pattern , the system comprising:an automated motor pump configured to facilitate aspiration of the thrombus, the automated motor pump comprising an external control panel configured to receive input from an operator; andpower electronics configured to power and control the automated motor pump to generate a plurality of variable suction patterns having a plurality of intensity levels, a first intensity level having a first negative pressure; and', 'a second intensity level having a second negative pressure,', 'wherein the first negative pressure is between 551 and 769 mm Hg, and', 'wherein the first negative pressure is more negative than the second negative pressure;, 'wherein the plurality of intensity levels compriseswherein a first variable suction pattern of the plurality of variable suction patterns comprises a repetitive cycle comprising the first intensity level for a first duration and the second intensity level for a second duration after the first duration,wherein the first duration and the second duration are each between 1 and 30 seconds, andwherein a total duration of the repetitive cycle of the first variable suction pattern is between 1 minute and 15 ...

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Номер записи: 33
09-01-2020 дата публикации

DEVICE AND METHOD FOR SEALING A MEMBRANE

Номер: US20200008788A1
Автор: DEVAUD Yannick, EHRBAR Martin, MILLERET Vincent, OCHSENBEIN Nicole, ZIMMERMANN Roland
Принадлежит: UNIVERSITAET ZÜRICH

Disclosed embodiments relate to a membrane closure device () for closing a perforation in a membrane (), comprising: a patch guiding mechanism () for guiding at least one expandable patch () to a perforation site () of a membrane (); and a fastener delivery mechanism () for delivering a fastener () to the perforation site () and for fastening the at least one expandable patch by the fastener () to the membrane () to seal the perforation in the membrane () by the at least one expandable patch (). 110010100. A membrane closure device () for closing a perforation in a membrane () having a proximal side and a distal side , the membrane closure device () comprising:{'b': 120', '122', '150', '140, 'a patch () that is selectively expandable from a narrow to an expanded configuration and having in the expanded configuration a concave surface () defining a retention cavity () for receiving glue ();'}{'b': 110', '120', '10, 'a patch delivery mechanism () for guiding the patch () through a perforation of the membrane () from a proximal to a distal side thereof;'}{'b': 130', '330', '140', '140', '10', '120', '140', '10, 'a fastener delivery mechanism (, ) operable to contain glue () and further operable to deliver the glue () contained therein from the proximal side to the distal side of the membrane () for fastening the patch () in the expanded configuration, by the glue (), to the distal side of the membrane () to seal the perforation.'}2100150140130330. The membrane closure device () of claim 1 , wherein the retention cavity () defines a volume that is larger than a volume of glue () that can be contained claim 1 , at any given time claim 1 , by the fastener delivery mechanism ( claim 1 , ).31001201201610. The membrane closure device () according to claim 1 , comprising at least one tube having a distal and a proximal end for delivering the patch () in a folded configuration via the at least one tube from the distal to the proximal end for attaching the patch () in an ...

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Номер записи: 34
08-01-2015 дата публикации

Silicon fistula plug for intestinal fistula

Номер: US20150012036A1
Автор: M. Tahir Özer
Принадлежит: Individual

The present invention is related to an apparatus to close and control the fistula especially in the enteroatmospheric fistulas occurred in surgical patients, characterized in that it comprises a silicon plug ( 1 ) that is made of silicon, and has a flexible, flat and circular shape; a2 connection part ( 2 ) that is integrated with silicone plug ( 1 ) made of same material and connecting the silicon plug to the suspensory band; at the other end of the connection part, a suspensory band ( 3 ) made of latex and having flexible circular form; and a bridge part ( 6 ) which is connected to the said structures in order to carry thereof, two surfaces of which are covered with thin sponge part ( 4 ), which has an easily bendable thickness and softness, and comprises an aluminum part ( 5 ) between sponge parts ( 4 ) at the center.

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Номер записи: 35
03-02-2022 дата публикации

DEVICES AND METHODS FOR THE TREATMENT OF VASCULAR ABNORMALITIES

Номер: US20220031295A1
Автор: Morin Kristen, Samaray Andrey, Springer Trevor
Принадлежит:

Described herein is a medical device for treating a target site. The medical device includes a proximal end including a disc and a distal end including a lobe. The disc and lobe are connected by a connecting member. The disc includes a proximal surface, a distal surface, and a central surface extending between and connecting the proximal surface and distal surface, wherein the central surface separates the proximal surface from the distal surface by a predetermined depth distance. 1. A medical device for treating a target site , the medical device comprising:a proximal end and a distal end, wherein the proximal end comprises a disc and the distal end comprises a lobe, wherein the disc and lobe are connected by a connecting member, wherein the disc comprises a proximal surface, a distal surface, and a central surface extending between and connecting the proximal surface and distal surface, wherein the central surface separates the proximal surface from the distal surface by a predetermined depth distance.2. The medical device of claim 1 , wherein the proximal surface claim 1 , distal surface claim 1 , and the central surface define a cavity.3. The medical device of claim 1 , wherein the disc is substantially three-dimensional in shape.4. The medical device of claim 3 , wherein the three-dimensional shape is one of rectangular claim 3 , half rounded claim 3 , rounded claim 3 , or trapezoidal.5. The medical device of claim 1 , wherein the proximal surface has a first length and the distal surface has a second length.6. The medical device of claim 5 , wherein the first length of the proximal surface is approximately equal to the second length of the distal surface.7. The medical device of claim 6 , wherein the central surface extends linearly between the proximal surface and the distal surface.8. The medical device of claim 6 , wherein the central surface is curved between the proximal surface and the distal surface.9. The medical device of claim 5 , wherein the first ...

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Номер записи: 36
19-01-2017 дата публикации

Endoscopic Hemostasis Closure Device And Delivery System

Номер: US20170014126A1
Автор: BEAN Jeffrey V.
Принадлежит:

A device for inserting a medical apparatus into a living body includes a handle and an elongated sheath extending from the handle to a distal end configured for insertion to a target location in the living body in combination with a clasp positioned within a distal portion of the elongated sheath and configured to temporarily attach to an endoscopic device and a spring retention mechanism movable from a first resting configuration maintaining a first closed position of the clasp to a second compressed configuration moving the clasp to an open position. A withdrawal mechanism is movable from a first resting configuration in which the distal end of the elongated sheath extends distally over a distal end of the endoscopic device to a second retracted configuration in which the distal end of the elongated sheath is moved proximally of the distal end of the endoscopic device. 125-. (canceled)26. A tissue clipping system , comprising:an elongated sheath extending from a proximal end to a distal end configured for insertion to a target location in the living body;a tissue clip comprising first and second legs extending distally from a base portion, each of the first and second legs including first and second elongated portions coupled to one another via a first hinge to permit angling of the first and second elongated portions relative to one another; anda clasp positioned within a distal portion of the elongated sheath and configured to releasably grasp the base portion of the tissue clip, the clasp comprising first and second arms configured to be movable from a closed configuration to an open configuration.27. The system of claim 26 , wherein the first and second elongated portions are coupled to one another by a pivot joint permitting angling of each of the elongated portions at any angle.28. The system of claim 26 , wherein the tissue clip is biased toward an open configuration in which each of the first and second legs extends transverse to a longitudinal axis of the ...

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Номер записи: 37
28-01-2016 дата публикации

TISSUE AND VASCULAR CLOSURE DEVICES AND METHODS OF USE THEREOF

Номер: US20160022252A1
Автор: Walsh Brandon G., ZHANG Ji
Принадлежит:

Devices and methods for closing access points in tissue are described. The devices include a tubular element fabricated form, for example, biologic material, a biologic tubular structure, or synthetic material. Using minimally invasive procedures, the devices and methods described herein allow implantation of the tubular element through the access point or wound such that it traverses the tissue. The tube has a sealed end which prevents leakage of fluid from, for example, the heart or a vessel upon securing the tube to the tissue. 1. A vascular closure device comprisinga sealing tube, wherein said sealing tube comprises a first end at the distal end of the sealing tube which is open and a second end at the proximal end of the sealing tube which is closed,a sheath which encases at least a portion of the sealing tube,a pusher cable positioned within the flexible tube, wherein the distal end of the pusher cable comprises one or more counters,wherein the pusher cable is moveably associated with the sealing tube, andwherein the sealing tube is moveably associated with the sheath, andwherein the outer surface of a distal portion of the sealing tube comprises an adhesive element.2. The closure device of claim 1 , wherein the sealing tube is comprised of pericardial tissue.3. The closure device of claim 1 , wherein the adhesive element is selected from one or more barbs or one or more suction cups.4. The closure device of claim 1 , wherein the second end is closed by a knot in the flexible tube.5. A method of closing a puncture in a blood vessel comprising use of the closure device of claim 1 , and comprising the steps:advancing the tubular closure device in a distal direction to the puncture wound until the distal end of the device is located past the puncture wound:pushing a pusher cable in a distal direction until the plurality of pusher arms radially expand away from the longitudinal axis of the sealing tube;pushing the nose cone in a distal direction to uncover the ...

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Номер записи: 38
28-01-2016 дата публикации

DEVICES, SYSTEMS, AND METHODS FOR INVERTING AND CLOSING THE LEFT ATRIAL APPENDAGE

Номер: US20160022273A1
Автор: Kassab Ghassan S.
Принадлежит:

Devices, systems, and methods are disclosed for inverting and closing a left atrial appendage. Certain methods include the steps of inverting a distal portion of a left atrial appendage and constraining the inverted portion using at least a snare device configured to be fit around the inverted portion of the left atrial appendage and closed, so that the inverted portion is securely circumscribed and closed. Devices and systems related to such methods are also described and include a catheter system comprising a vacuum tube and a snare slidably disposed within a catheter. 1. A system for inverting and closing a left atrial appendage , the system comprising:a catheter configured for introduction into a mammalian blood vessel and advancement to a left atrium of a heart and into a left atrial appendage, the catheter comprising an elongated tubular body having a proximal end, a distal end, and defining a lumen extending between the proximal and distal ends;a vacuum tube comprising a proximal end, a distal end, and a first lumen extending between the proximal and distal ends, the distal end of vacuum tube configured to engage a targeted tissue; anda snare comprising an elongated wire having a proximal end, a distal end and a separation mechanism, the distal end configured to move from an open position to a closed position and the separation mechanism configured to detach the distal end from the proximal end upon activation;wherein the vacuum tube and the snare are slidably disposed within the lumen of the tubular body and each configured for advancement through the distal end of the tubular body.2. The system of claim 1 , wherein the separation mechanism is selected from a group consisting of a slicing mechanism claim 1 , a cutting mechanism claim 1 , a weakened region of the elongated wire claim 1 , and a snap-fastener mechanism.3. The system of claim 2 , wherein activation of the separation mechanism comprises the application of a proximal force.4. The system of claim 1 ...

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Номер записи: 39
26-01-2017 дата публикации

TISSUE CLOSURE DEVICE

Номер: US20170020496A1
Автор: Yribarren Travis R.
Принадлежит:

A tissue closure device including a hub and first and second flanges extending therefrom. The hub extends along a central longitudinal axis between a proximal surface and an opposing distal surface. The first flange is frameless and extends from the hub adjacent the proximal surface thereof. The second flange extends from the hub adjacent the distal surface thereof. The first and second flanges are moveable between: a closed position, in which the first and second flanges extend radially away from the hub and are substantially orthogonal to the central longitudinal axis; and an open position, in which the first and second flanges extend longitudinally away from the hub in opposite directions from each other and are substantially parallel with the central longitudinal axis. 1. A tissue closure device for closing an opening in body tissue , the tissue closure device comprising:a hub extending along a central longitudinal axis between a proximal surface and an opposing distal surface;a first flexible yet resilient frameless flange extending from the hub adjacent the proximal surface thereof;a second flange extending from the hub adjacent the distal surface thereof; a closed position, in which the first and second flanges extend radially away from the hub and are substantially orthogonal to the central longitudinal axis, and', 'an open position, in which the first and second flanges extend longitudinally away from the hub in opposite directions from each other and are substantially parallel with the central longitudinal axis., 'the first and second flanges being movable between2. The tissue closure device according to claim 1 , wherein the second flange is also frameless and flexible yet resilient.3. The tissue closure device according to claim 1 , wherein the tissue closure device is biabsorbable.4. The tissue closure device according to claim 1 , wherein the first and second flanges are substantially parallel with each other in the closed position such that the first ...

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Номер записи: 40
28-01-2016 дата публикации

Method of treating pleural abnormality

Номер: US20160022878A1
Автор: Hao-Ying Hsieh, Hong-Shiee Lai, Hsu-Hsien Chang, Jin-Shing Chen, Ke-Cheng Chen, Tai-Horng Young, Ya-Shuan CHOU, Yong-Chong Lin
Принадлежит: National Taiwan University NTU

The invention relates to a method of treating pleural abnormalities in a subject in need thereof, comprising the steps of: (a) attaching a biodegradable polymeric membrane onto a pleural wound to elicit fibronectin from fibroblasts to cause fibrous adhesion; and (b) securing the membrane with securement products, including sutures, staples, and sealants. The present invention also relates to a biodegradable adhesion membrane used for treating pleural abnormalities, comprising: a biodegradable base material selected from the group consisting of polycaprolactone (PCL), polylactic acid or polylactide (PLA), polyhydroxybutyrate (PHB), poly(ethylene adipate), poly(butylene adipate) (PBA), chitosan, hyaluronic acid, and polyglycolic acid (PGA); wherein the thickness of the membrane is 0.1-1 mm.

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Номер записи: 41
10-02-2022 дата публикации

COLLAPSIBLE TUBE FOR HEMOSTASIS

Номер: US20220039781A1
Автор: LARZON Cecilia, LARZON Thomas
Принадлежит:

Collapsible tube embodiments may be used to promote hemostasis at surgical sites or any other suitable location. In some cases, vascular closure device embodiments may include collapsible tube embodiments in order to promote hemostasis at a surgical site during a vascular closure procedure. 1. A method of preventing blood leakage from a closure site of a passage in a tissue layer , comprising:disposing a distal end of a housing of a vascular closure device to a position adjacent the passage in the tissue layer;deploying a plurality of anchor deployers from a distal section of the housing in a distal and radially outward direction from the housing into the tissue layer in positions disposed about the passage in the tissue layer;penetrating the tissue layer with the plurality of anchor deployers of the vascular closure device and extending each of the plurality of anchor deployers distally through the tissue layer until a proximal end of a collapsible tube of each of the plurality of anchor deployers extends distally beyond a lower surface of the tissue layer;proximally retracting an anchor of each of the anchor deployers by proximally retracting a filament which is secured thereto;axially compressing the collapsible tube of each of the plurality of anchor deployers between the respective anchor and lower surface of the tissue layer by applying tension to the filament which is secured to the anchor and which is disposed within an inner lumen of the collapsible tube until the collapsible tube shortens in axial length and expands in an outward radial direction adjacent the passage; andapplying tension to the filaments from a distal section of the housing to reduce a distance between the anchors drawing the anchors and adjacent tissue of the tissue layer radially inward so as to reduce the size of the passage in the tissue layer.2. The method of further comprising proximally withdrawing deployment rods of each of the plurality of anchor deployers from respective anchors ...

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Номер записи: 42
10-02-2022 дата публикации

METHODS AND SYSTEMS FOR SEALING A PUNCTURE OF A VESSEL

Номер: US20220039782A1
Автор: Phillips Victor Matthew
Принадлежит:

A system to facilitate sealing a puncture of a vessel includes an implant having first and second expandable sections, and a delivery device that includes an inner tube and a circumscribing outer tube. The outer tube defines a first lumen configured to retain the implant, and a second lumen configured to channel fluid from the vessel through a distal opening proximal to the implant. A pusher circumscribed at least partially by the outer tube is configured to compress the implant to selectively expand the first and second expandable sections. The outer tube is selectively retractable relative to the inner tube such that the first expandable section remains substantially within the first lumen and the second expandable section is positioned outside of the first lumen. The outer tube is further selectively retractable relative to the inner tube such that the first expandable section is positioned outside of the first lumen. 121-. (canceled)22. A system to facilitate sealing a puncture of a vessel , said system comprising:an implant comprising an implant distal end, a first expandable section, and a second expandable section; anda delivery device comprising:an inner tube comprising (i) an inner tube distal end and (ii) an expandable portion adjacent said inner tube distal end, wherein said expandable portion is selectively actuatable between (i) a stopper configuration that defines a retaining lip, such that said implant distal end is retained on said hypo tube proximally of said retaining lip, and (ii) a neutral configuration configured to release said implant distally over said inner tube;an outer tube circumscribing at least a portion of said inner tube, said outer tube defining a first lumen configured to retain said implant in a delivery configuration and a second lumen configured to channel a fluid from the vessel through a distal opening of said second lumen, said distal opening longitudinally located one of (i) adjacent to said implant and (ii) proximal to said ...

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Номер записи: 43
10-02-2022 дата публикации

Skull Base Closure Systems And Methods

Номер: US20220039851A1
Автор: Johannes Jacobus JACOBS, Patrick Eoin CUSHEN
Принадлежит: Stryker European Holdings I LLC

The present disclosure provides a bioresorbable foam closure device for trans-nasally closing an opening in a base of a skull. The closure device comprises a phase-separated polymer having a porosity of greater than 80%. The device includes a stem portion having a proximal end and a distal end, and a head portion at the distal end of the stem portion. The closure device is deformed from a free shape to a constricted shape, inserted through a nasal cavity and into the opening, and released to at least partially revert back to the free shape such that the stem portion fills the opening and the head portion abuts cranium and dura to secure the closure device in position and seal the opening.

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Номер записи: 44
24-01-2019 дата публикации

LEFT ATRIAL APPENDAGE OCCLUDER

Номер: US20190021711A1
Автор: LI Anning
Принадлежит: LIFETECH SCIENTIFIC (SHENZHEN) CO., LTD.

A left atrial appendage occluder, including a closure disc and a bracket connected to the closure disc; the closure disc includes a frame; the frame includes a proximal-end disc face and a distal-end disc face; the proximal-end disc face includes flexible proximal-end support rods arranged radially; the distal-end disc face includes flexible distal-end support rods arranged radially; the floating end of each of the flexible proximal-end support rods is connected to the floating end of the adjacent flexible distal-end support rod The flexible proximal-end support rod at the point of largest diameter of the closure disc is arranged independent of the distal-end support rod; thus the degree of freedom of deformation at the point of largest diameter of the closure disc is increased, ensuring that the outer edge of the closure disc may adapt to fit the openings of various irregular left atrial appendages. 121-. (canceled)22. A left atrial appendage occluder , comprising:a sealing plate and a fixing frame connected with the sealing plate, wherein the sealing plate comprises a proximal disk surface and a distal disk surface;the proximal disk surface comprises a plurality of elastic proximal supporting rods arranged in a radiated manner in a radial direction;the distal disk surface comprises a plurality of elastic distal supporting rods arranged in a radiated manner in the radial direction; anda hanging end of each proximal supporting rod is connected with a hanging end of one distal supporting rod adjacent to the proximal supporting rod.23. The left atrial appendage occluder according to claim 22 , wherein the proximal disk surface comprises a proximal seal head;one end of each proximal supporting rod is connected with the proximal seal head, and the other end of the proximal supporting rod is radiated in the radial direction and is hanging; the distal disk surface comprises a distal seal head; andone end of each distal supporting rod is connected with the distal seal head ...

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Номер записи: 45
23-01-2020 дата публикации

TISSUE ANCHORS WITH HEMOSTASIS SEAL

Номер: US20200022697A1
Автор: Campbell Thomas, DENTI Paolo, GILMORE Michael, GUIDOTTI Andrea, LYNN Kevin, MULLINS John, Murphy Charlotte, VANERMEN Hugo
Принадлежит: 4TECH INC.

A tissue anchor is provided that includes a head connected to a shaft, and a tissue-coupling element extending from the shaft. When the tissue anchor is unconstrained, the head is coaxial with an axis of the shaft, and the tissue-coupling element is generally orthogonal to the axis and is shaped such that if the tissue-coupling element were to be projected onto a plane that is perpendicular to the axis, (a) at least 80% of an area of a projection of the tissue-coupling element on the plane would fall within a first angle of 180 degrees in the plane having a vertex at the axis, and (b) the area would partially overlap, at least 3 mm from the vertex, both rays of a second angle of between 45 and 180 degrees in the plane having the vertex at the axis. Other embodiments are also described. 1. Apparatus for delivery through tissue in a constrained state within a deployment tool , the apparatus comprising a tissue anchor , which comprises:a shaft, which comprises a seal;a head connected to a proximal portion of the shaft; anda tissue-coupling element, which extends from a distal end of the shaft, the shaft has a central longitudinal axis,', 'the head is coaxial with the central longitudinal axis, and', 'the tissue-coupling element is generally orthogonal to the central longitudinal axis of the shaft and is shaped such that if the tissue-coupling element were to be projected onto a plane that is perpendicular to the central longitudinal axis, (a) at least 80% of an area of a projection of the tissue-coupling element on the plane would fall within a first angle of 180 degrees in the plane having a vertex at the central longitudinal axis, and (b) the area would partially overlap, at least 3 mm from the vertex, both rays of a second angle of between 45 and 180 degrees in the plane having the vertex at the central longitudinal axis., 'wherein, when the tissue anchor is unconstrained by the deployment tool2. The apparatus according to claim 1 , wherein at least 95% of the area ...

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Номер записи: 46
02-02-2017 дата публикации

LEFT ATRIAL APPENDAGE IMPLANT

Номер: US20170027552A1
Автор: Connolly Patrick, Folan Martyn G., Horgan Fergal, Turkington Marie
Принадлежит: Cardiac Pacemakers, Inc.

A medical implant for a left atrial appendage may include a central member having an anchor at a distal end and a plurality of legs joined together at a joint coupled to the central member. The plurality of legs may be configured to expand from a delivery configuration to a deployed configuration. A medical implant may include a central shaft having an anchor at a distal end and a cup-shaped occluder fixed to a proximal end of the central shaft, the occluder being configured to expand from a delivery configuration to a deployed configuration and retard tissue ingrowth thereon. A medical implant system may include a delivery sheath, an implant having an expandable frame including a plurality of legs each having an anchor and a mesh having a plurality of openings therethrough attached to the frame, and a plurality of particles disposed within the delivery sheath. 1. A medical implant for use in a left atrial appendage , comprising:a central elongated member having an anchor at a distal end thereof; anda plurality of elongated metallic legs joined together at a joint, the joint being coupled to the central elongated member;wherein the plurality of elongated metallic legs is configured to expand radially outward from a delivery configuration to a deployed configuration.2. The medical implant of claim 1 , wherein each of the plurality of elongated metallic legs extends proximally from the joint to a proximal tip.3. The medical implant of claim 1 , wherein each of the plurality of elongated metallic legs extends distally from the joint to a distal tip.4. The medical implant of claim 1 , wherein the central elongated member is rotatable within the joint.5. The medical implant of claim 1 , wherein the anchor is fixed to the central elongated member.6. The medical implant of claim 5 , wherein the anchor is a helical coil.7. The medical implant of claim 5 , wherein the anchor includes one or more barbs extending radially outward from the central elongated member.8. The ...

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Номер записи: 47
29-01-2015 дата публикации

Aspiration systems

Номер: US20150032120A1
Автор: Vallabh Janardhan, Vikram JANARDHAN
Принадлежит: Insera Therapeutics Inc

Thrombus aspiration may be performed using manual negative intermittent suction (e.g., provided by a syringe) or using an automated negative suction device (e.g., provided by a vacuum pump). The suction device may be connected through suction tubing to a hub of a catheter. The automated negative suction device may include an external control panel for the operator configured to allow the operator to choose from any of a plurality of suction patterns during an aspiration procedure.

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Номер записи: 48
09-02-2017 дата публикации

Left atrial appendage occluder device anchoring system, anchor, and method of attachment

Номер: US20170035433A1
Автор: Thomas J. Forbes
Принадлежит: Individual

The present invention relates in general to anchoring systems for occluder devices, and more specifically, to an anchoring system and method for implanting an occluder device within a left atrial appendage (“LAA”) of the heart. The anchoring system is configured so that an anchor penetrates the inner endocardium layer, middle myocardium layer, and outer epicardium layer of an LAA wall. The purpose of the present invention is to provide an occluder device anchor that has a low risk of embolization and/or causing injury to neighboring valve structures. An additional purpose of the present invention is to provide an anchoring system and method for implanting an occluder device within the LAA that allows for the occluder device to be retrievable after initial placement, reusable, and repositionable for an optimal final placement within the LAA.

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Номер записи: 49
09-02-2017 дата публикации

HEART OCCLUSION DEVICES

Номер: US20170035435A1
Автор: Amin Zahid, Cully Edward H., Cutright Warren, Larsen Coby C., Masters Steven J., Shaw Edward E.
Принадлежит:

This disclosure is directed to an aperture occlusion device and a method for occluding an aperture, including a perimembranous ventricular septal defect. The aperture occlusion device includes a wire frame element. The wire frame forms geometric shapes that include an occluder region and a securing region. The occluder region and the securing region are separated by an attachment region including a waist. The occluder region and securing region can include membranous coverings. The device can be attached to a delivery hub. The wires forming the occluder region and securing region can have a shape-memory capability such that they can be collapsed and distorted in a sheath during delivery, but resume and maintain their intended shape after delivery. 1. A method for occluding a defect in an anatomical feature using an occluder device defining a proximal end and a distal end and including a plurality of wires each extending continuously between the proximal and distal ends of the device and forming a proximal disc defining a proximal outer perimeter of the device , a distal disc defining a distal outer perimeter of the device , and a waist arranged between the proximal disc and the distal disc and defining a narrowed region of the device between the proximal and distal outer perimeters , the method comprising:traversing a delivery catheter through the defect;deploying the distal disc by advancing the occluder device from the delivery catheter to expand the distal disc;deploying the waist section by further advancing the occluder device from the delivery catheter to expand the waist and positing the waist within the defect;deploying the proximal disc by advancing the occluder device from the delivery catheter to expand the proximal disc and fully deploying the occluder device such that each of the plurality of wires include: a first linear section extending radially outward from the central axis of the device toward the proximal outer perimeter of the device, a first ...

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Номер записи: 50
05-02-2015 дата публикации

IMPLANT RETRIEVAL SYSTEM

Номер: US20150039021A1
Автор: Frazier Andrew G.C., Khairkhahan Alexander K., Klenk Alan R., Kreidler Marc S., Kume Stewart M., Ogi Darrell H., Roue Chad C., Van der Burg Erik J.
Принадлежит:

Disclosed is an adjustable occlusion device for use in a body lumen such as the left atrial appendage. The occlusion device is removably carried by a deployment catheter. The device may be enlarged or reduced to facilitate optimal placement or removal. Methods are also disclosed. 1. A retrieval catheter for retrieving a device from an implantation site within the body, comprising: an elongate, flexible body, having a proximal end and a distal end; a grasping structure on the distal end, for grasping the device; a flared tubular sleeve, for surrounding at least a portion of the device; and an outer tubular sleeve, for surrounding the flared tubular sleeve. This application is a continuation of U.S. patent application Ser. No. 13/617,308, filed Sep. 14, 2012, which is a continuation of U.S. patent application Ser. No. 10/441,600, filed May 19, 2003, now U.S. Pat. No. 8,287,563, which is a divisional of U.S. patent application Ser. No. 10/033,371, filed Oct. 19, 2001, now U.S. Pat. No. 7,044,134, which is a continuation-in-part of U.S. patent application Ser. No. 09/435,562, filed Nov. 8, 1999, now U.S. Pat. No. 7,128,073, the disclosures of which are incorporated in their entirety herein by reference.Embolic stroke is the nation's third leading killer for adults, and is a major cause of disability. There are over 700,000 strokes per year in the United States alone. Of these, roughly 100,000 are hemoragic, and 600,000 are ischemic (either due to vessel narrowing or to embolism). The most common cause of embolie stroke emanating from the heart is thrombus formation due to atrial fibrillation. Approximately 80,000 strokes per year are attributable to atrial fibrillation. Atrial fibrillation is an arrhythmia of the heart that results in a rapid and chaotic heartbeat that produces lower cardiac output and irregular and turbulent blood flow in the vascular system. There are over five million people worldwide with atrial fibrillation, with about four hundred thousand new ...

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Номер записи: 51
08-02-2018 дата публикации

Engagement catheter devices, systems, and methods to use the same under suctional tissue engagement

Номер: US20180036514A1
Автор: Ghassan S. Kassab, Jose A. Navia, SR.
Принадлежит: CVDevices LLC

Engagement catheter devices, systems, and methods to use the same under suctional tissue engagement. A method of the present disclosure comprises the steps of engaging a targeted tissue under suction/vacuum using an engagement catheter, delivering a substance into or through the targeted tissue using a needle positioned within a first lumen of the engagement catheter, injecting a fluid within the first lumen of the engagement catheter to flush at least part of the first lumen with the fluid, and suctionally removing the injected fluid from within the first lumen of the engagement catheter.

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Номер записи: 52
24-02-2022 дата публикации

Devices and methods for occlusion of an atrial appendage

Номер: US20220054143A1
Автор: Aaron D. Fox, Brett J. Wham, Charles J. Center, Edward E. Shaw, Nathan C. Korey, Nicholas S. Webster, Peter J. Zeller, Roark N. Wolfe
Принадлежит: WL Gore and Associates Inc

Various aspects of the present disclosure are directed toward apparatuses, methods, and systems as relating to occlusion. In certain instances, the apparatuses, methods, and systems may include a device for placement in vessels, appendages, and openings in a body. The device may include a unitary frame having a face portion that includes a center frame portion a plurality of elongate members.

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Номер записи: 53
06-02-2020 дата публикации

Uncoupled LAA Device

Номер: US20200038004A1
Автор: Corcoran Michael Patrick, Marino Joseph A., Tan Englong
Принадлежит: Cardia, Inc

A medical device for treating an LAA is presented. The device includes a cap, a bulb and a joint assembly therebetween. The cap is a three layer mesh structure with a retaining hub securing the layers together. A plurality of proximal wire loops extend from the base layer to a proximal post of the joint assembly. The bulb has a plurality of distal wire loops that extend between a terminal post and a distal post of the joint assembly. The joint assembly comprises a first ball joint, a second ball joint and a housing. Each ball joint is retained in the housing independent ball and socket relationships. Each ball joint and post defines a longitudinal axis. The housing defines a housing longitudinal axis. By way of the ball and socket relationship each ball joint longitudinal axis may form an angle of between about 0 to about 35 degrees with the housing longitudinal axis in any direction. 1. A medical device to treat the LAA , the medical device having a deployed state and a confined state , the medical device comprising:a cap, a bulb and a joint assembly therebetween;the cap having a plurality of layers, one of the layers defining a base layer, the base layer constructed of at least two sections of mesh material immediately adjacent to one another, a plurality of proximal wire loops extending from the cap to a proximal post of the joint assembly;the bulb having a plurality of distal wire loops that extend between a terminal post and a distal post of the joint assembly, adjacent distal wire loops being connected one to another by at least one connection collar;the joint assembly comprising a first ball joint, a second ball joint and a housing, the proximal post extending proximally from the first ball joint, the distal post extending distally from the second ball joint, the housing having a proximal collar and a distal collar, the proximal collar retaining the first ball joint in a first ball and socket relationship, the distal collar retaining the second ball joint in ...

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Номер записи: 54
06-02-2020 дата публикации

AN OCCLISIVE MEDICAL IMPLANT

Номер: US20200038033A1
Автор: Clark Christopher J., DORAN BURNS P., McPhail Mark, Peiffer Dennis A., TISCHLER BRIAN J.
Принадлежит: Boston Scientific Scimed Inc.

An occlusive medical implant having a frame actuatable between a collapsed delivery configuration and an expanded implanted configuration, the frame including a generally tubular portion with a threaded insert configured to removably attach to a threaded distal end of a core wire; an occlusive element disposed on the frame; where a proximal portion of the occlusive element and the proximalmost extent of the threaded insert are substantially coplanar with a plane defined by three or more proximalmost extents of the frame in the expanded implanted configuration. 1. (canceled)2. A medical implant , comprising:a frame configured to actuate between a collapsed configuration and an expanded configuration,wherein the expanded configuration of the frame is compliant and is configured to substantially conform to a shape and/or geometry of a lateral wall of a left atrial appendage; and to be in sealing engagement therewith when implanted in the left atrial appendage;an occlusive element configured to cover at least a proximal portion of the frame, which proximal portion spans an opening formed by the lateral wall of the left atrial appendage in the expanded configuration of the frame, and is configured to cover at least a portion of the lateral wall of the left atrial appendage distal of the opening;wherein a proximal end of the frame includes a generally tubular portion, the generally tubular portion being configured to attach to a distal end of a core wire;wherein the generally tubular portion of the frame includes a threaded insert coupled thereto,wherein a proximalmost extent of the threaded insert is substantially coplanar with a plane defined by three or more proximalmost extents of the frame in the expanded configuration,wherein the portion of the occlusive element covering the opening is substantially coplanar with the proximalmost extent of the threaded insert and the plane defined by the proximalmost extent of the frame in the expanded configuration.3. The medical ...

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Номер записи: 55
06-02-2020 дата публикации

Vessel Occluder

Номер: US20200038034A1
Автор: Graczyk Beuthin Wendy, Liang Jessica, Luong-Uhl Tin, Maguire Shannon, Soliman Peter
Принадлежит: Terumo Corporation

A vessel occluder used to occlude blood flow within the vasculature is described. The vessel occluder can include an expandable mesh portion having a flexible membrane that expands within a cavity of the expandable mesh portion. When expanded, the flexible membrane blocks blood passage through the mesh portion. 1. A vascular plug comprising:a mesh portion having a radially compressed configuration when constrained in a catheter and a radially expanded configuration when unconstrained;a proximal support arm spanning a proximal section of an interior of the mesh portion and forming a ring portion in the interior of the mesh portion; anda membrane fixed to the ring portion, the membrane adopting a radially expanded configuration as the mesh portion adopts its radially expanded configuration, thereby limiting blood passage through the mesh portion.2. The vascular plug of claim 1 , further comprising a distal support arm spanning a distal section of the interior of the mesh portion.3. The vascular plug of claim 2 , wherein the distal support arm is connected to a distal end of the mesh portion.4. The vascular plug of claim 2 , wherein the proximal and distal support arms form the ring portion.5. The vascular plug of claim 2 , wherein the proximal support arm and the distal support arm curve radially outwardly near a center of the mesh portion to define the ring portion.6. The vascular plug of claim 1 , wherein the membrane expands to an orientation that is perpendicular to an axis between the proximal end and the distal end of the mesh portion.7. The vascular plug of claim 1 , wherein the membrane expands within the interior of the mesh portion at a non-perpendicular angle relative to an axis of the elongated pusher.8. The vascular plug of claim 1 , wherein the proximal support arm is connected to a proximal end of the mesh portion.9. The vascular plug of claim 1 , wherein the membrane comprises PET.10. A vascular plug comprising:a mesh portion having a radially ...

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Номер записи: 56
18-02-2021 дата публикации

METHOD AND APPARATUS

Номер: US20210045691A1
Автор: Bahmanyar Mohammad Reza, McLeod Christopher Neil, Zou Longfang
Принадлежит: IP2IPO INNOVATIONS LIMITED

An implantable intracardiac apparatus for implantation in a wall of the heart to secure a pressure sensor thereto, the apparatus comprising: a mesh configured to collapse to enable it to be carried, by a catheter, to a deployment site in the heart, and to expand upon deployment from the catheter to provide a conformable mesh layer for securement against the wall of the heart; wherein the conformable mesh layer comprises an opening occupied by a compliant diaphragm that is flush with the mesh layer, or recessed with respect to the mesh layer, when the mesh layer is secured against the wall of the heart; the apparatus further comprising a can for holding said pressure sensor, and the compliant diaphragm provides a wall of the can. 1. An implantable intracardiac apparatus for implantation in a wall of the heart to secure a pressure sensor thereto , the apparatus comprising: collapse to enable it to be carried, by a catheter, to a deployment site in the heart, and to', 'expand upon deployment from the catheter to provide a conformable mesh layer for securement against the wall of the heart;', 'wherein the conformable mesh layer comprises an opening occupied by a compliant diaphragm that is flush with the mesh layer, or recessed with respect to the mesh layer, when the mesh layer is secured against the wall of the heart;, 'a mesh configured tothe apparatus further comprising a can for holding said pressure sensor, and the compliant diaphragm provides a wall of the can.2. The apparatus of wherein the can is arranged so that when the conformable mesh layer is secured to the wall of the heart the can is held between the wall of the heart and the diaphragm.3. The apparatus of wherein the can is for implantation in the wall of the heart claim 2 , and the mesh layer provides a flange around the opening.4. The apparatus of wherein the mesh layer is arranged so that upon implantation of the can into a surface of the wall of the heart claim 3 , the flange lies flush against a ...

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Номер записи: 57
16-02-2017 дата публикации

Minimally invasive methods and apparatus

Номер: US20170042516A1
Автор: Edward M. Boyle, Jr.
Принадлежит: Individual

Methods and apparatus are provided to facilitate the minimally invasive removal of tissue biopsies and to facilitate the direct approach to anesthetizing the chest wall, in accordance with embodiments of the present invention. A pull-type cutting device 1 comprises two coaxially nested tubes, each extending from a proximal end 21 to a distal end 22 . The first tube 61 defines a guide wire lumen 23 for slidingly receiving a guide wire. The second tube 63 extends over the first tube 60 and coupled thereto at the distal end 22 defining an expandable portion 13 adjacent the distal end 22 . The second tube 63 defines an inflation lumen 25 extending from the shaft proximal end 21 to the expandable portion 13 . The inflation lumen 25 communicates inflation fluid from the proximal end 21 to the expandable portion 13 so as to inflate and deploy the expandable portion 13 . Disposed adjacent the shaft distal end 22 is a cutting head 10 comprising the expandable portion 13 having a cutting portion 11 distal from the shaft distal end 22.

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Номер записи: 58
16-02-2017 дата публикации

Temporary occlusion balloon devices and methods for preventing blood flow through a vascular perforation

Номер: US20170042519A1
Автор: Grant FOY, Jay Harper, Phil ARANAS, Ryan Michael SOTAK
Принадлежит: Spectranetics LLC

A device for occluding a perforation in a blood vessel includes a catheter shaft that has a first lumen and a second lumen. The first lumen is adapted to receive at least one of a guidewire and an implanted cardiac lead, and the second lumen is adapted to receive an inflation fluid. The device further includes an inflatable balloon that is carried by the catheter shaft. The inflatable balloon is adapted to receive the inflation fluid from the second lumen. The inflatable balloon has a working length of about 65 mm to about 80 mm and an inflated diameter of about 20 mm to about 25 mm.

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Номер записи: 59
15-02-2018 дата публикации

SEALING DEVICE AND DELIVERY SYSTEM

Номер: US20180042592A1
Автор: BROWN Tyler J., Hua Khoa, Nelson Devin M., Rust Keith O.
Принадлежит:

A medical device for sealing a defect in a body includes a wire frame that includes a plurality of wires that form a first occluding member and a second occluding member. In some embodiments, a sealing member is in contact with the wire frame. In some embodiments, the sealing member is configured to define one or more openings in the sealing member. 1. A medical device comprising: a first eyelet,', 'a second eyelet,', 'a first disc member,', 'a second disc member, and', 'a defect-occupying portion disposed between the first disc member and the second disc member; and, 'a plurality of wound wires forminga sealing member in contact with the frame including one or more openings configured to at least partially prevent or relieve a fluid pressure differential between an interior and an exterior of the sealing member, the sealing member forming a first occluding member with the first disc member and a second occluding member with the second disc member configured to seal a range of defect sizes from a largest defect size to a smallest defect size that is approximately 60% of the largest defect size.2. The medical device of claim 1 , wherein the one or more openings define passages through the sealing member.3. The medical device of claim 1 , wherein the one or more openings being configured to at least partially prevent or relieve the fluid pressure differential facilitates maintaining the medical device in a desired position and configuration in relation to the patient's anatomy.4. The medical device of claim 1 , wherein the one or more openings includes two claim 1 , three claim 1 , four claim 1 , five claim 1 , six claim 1 , seven claim 1 , eight claim 1 , nine claim 1 , ten claim 1 , eleven claim 1 , or twelve openings.5. The medical device of claim 1 , wherein the one or more openings are arranged on at least one of the first occluding member and the second occluding member.7. The medical device of claim 1 , wherein the range of defect sizes includes at least one of ...

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Номер записи: 60
16-02-2017 дата публикации

METHOD AND PROSTHESIS FOR PERCUTANEOUS HERNIA REPAIR

Номер: US20170042656A1
Автор: Keane David
Принадлежит:

A method and prosthesis is provided for percutaneous repair of an anatomical defect, such as an inguinal hernia. The method involves percutaneously accessing the inguinal canal of a patient. Following hernia reduction, if required, the hernia defect may be accessed and repaired percutaneously from within the inguinal canal. An implantable prosthesis may be percutaneously delivered into the inguinal canal. The prosthesis may be advanced along the inguinal canal from the percutaneous entry location to the defect site, where it may be deployed over and/or within the defect. A biocompatible foam material may be percutaneously delivered into the inguinal canal to reduce and/or repair the hernia defect. The foam may fill and solidify to in the canal to prevent abdominal viscera from reentering the canal. Ablative therapy may be performed within the inguinal canal to cause a fibrotic response resulting in scar tissue formation and/or tissue shrinkage that narrows the canal. 1. A method of percutaneously repairing an inguinal hernia defect , the method comprising acts of: (a) percutaneously accessing an inguinal canal of a patient; (b) percutaneously delivering a biocompatible foam material into the inguinal canal.2. The method according to claim 1 , wherein act (b) includes filling the inguinal canal with the foam material from the location of percutaneous access toward the hernia defect.3. The method according to claim 2 , wherein act (b) includes filling the inguinal canal to the inguinal ring.4. The method according to claim 1 , wherein the foam material solidifies in the shape of the inguinal canal.5. The method according to claim 1 , further comprising an act (c) of percutaneously plugging and/or covering the hernia defect with an implantable prosthesis.6. The method according to claim 5 , wherein act (c) occurs prior to act (b).7. The method according to claim 5 , wherein act (c) includes percutaneously delivering the prosthesis into the inguinal canal claim 5 , and ...

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Номер записи: 61
16-02-2017 дата публикации

IMPLANTABLE DEVICE FOR USE IN THE HUMAN AND/OR ANIMAL BODY TO REPLACE AN ORGAN VALVE

Номер: US20170042675A1
Автор: Freudenthal Franz
Принадлежит:

The invention relates to an implantable device for use in the human and/or animal body to replace an organ valve, comprising a main body having a first end and a second end, wherein the first end and the second each have an opening to provide a fluid connection through the main body between the first end and the second end; a first membrane element arranged inside or at one end of the main body, wherein the membrane element is formed in such a manner that it allows the fluid connection through the main body in a first flow direction and blocks the same in a second flow direction opposite the first flow direction; wherein the main body has a large ratio of length to transverse expansion along the longitudinal axis of the main body in a first operating state (primary form) and a smaller ratio of length to transverse expansion along the longitudinal axis of the main body in a second operating state (secondary form); and wherein the main body can be reversibly transferred from the secondary form to the primary form counter to elastic material forces by the application of a force; and wherein the main body is formed from a single wire-like element or from a plurality of wire-like elements connected to each other by means interlocking winding and/or twisting and/or weaving in the manner of a woven and/or layered fabric and/or net. 1. An implantable device for use in the human and/or animal body to replace an organ valve , comprising:a main body having a first end and a second end, wherein the first end and the second end each have an opening to provide a fluid connection through the main body between the first end and the second end;a first membrane element arranged inside or at one end of the main body, wherein the membrane element is formed in such a manner that it allows the fluid connection through the main body in a first flow direction and blocks the same in a second flow direction opposite the first flow direction;wherein the main body has a large ratio of length ...

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Номер записи: 62
03-03-2022 дата публикации

Asymmetric Occluder Device

Номер: US20220061828A1
Автор: Hijazi Ziyad Mousa, Malakan Rad Elaheh
Принадлежит: OCCLUTECH HOLDING AG

An asymmetric occlusion device for occluding an opening in a body tissue where part of the opening is defined by a partial inadequate rim. The asymmetric occlusion device includes a waist portion having a distal end extending to a proximal end. The waist portion is of non-woven material extending around a longitudinal axis opening. The occlusion device further includes a pair of asymmetric occluder disks attached to the waist. The asymmetric distal and proximal occluder disks are formed of shape memory material. The asymmetric occluder disks include a short arm extending from the waist and an extended arm extending from the waist. The extended arm exceeds the length of the first short arm. The density of the first short arm exceeds the density of the second extended arm.

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Номер записи: 63
03-03-2022 дата публикации

Devices, systems, and methods for pyloric occlusion

Номер: US20220061853A1
Автор: Darren G. Curran, Gerard DUIGNAN, James Quinn, Ryan D. Lynch
Принадлежит: Boston Scientific Scimed Inc

An occlusion device or plug having a proximal plug section and a distal plug section. The plug sections may each be shifted between an unexpanded configuration and an expanded configuration at the deployment site to occlude the deployment site. A tubular member such as a silicone tube may be used to form an occlusion device or plug shiftable or expandable into a desired configuration. An intermediate section between a proximal plug section and a distal plug section may be configured to be manipulated at least to shift at least one of the plug sections from an expanded configuration to an unexpanded configuration. A pair of stents may be coupled together via an intermediate section in such manner such that manipulation of the intermediate section causes at least one of the stents to shift from an expanded configuration to an unexpanded configuration.

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Номер записи: 64
14-02-2019 дата публикации

MULTI-FUNCTIONAL OCCLUDER

Номер: US20190046169A1
Автор: KONETI NAGESWARA RAO
Принадлежит:

The present invention is related to an occlusion device for occluding an opening in a body tissue and a method of deploying the said occlusion device to the site of defect. The construction of the occlusion device comprising two discs, that are centrally connected by a central portion and retention screws, is such that it offers the major advantage of haemodynamic adjustment providing a better-fit to the size of the defect. 1. A multi-functional occlusion device comprising of:a flexible proximal disc preferably a high-pressure disc and a flexible distal disc preferably a low-pressure disc;a septum;retention screws on the outer side of said proximal and distal discs; anda central geometrically shaped connector section;wherein the said proximal disc and distal disc are of uniform size, and straddle the said septum to provide stability on opposite sides of a defect; andthe said central geometrically shaped connector section is cone shaped, and provides hemodynamic adjustment of the said proximal disc and distal disc.2. The multi-functional occlusion device according to claim 1 , wherein the said proximal disc and distal disc function as high-pressure disc and low-pressure disc claim 1 , respectively claim 1 , in the ventricular and arterial sections wherein the pressure gradient is high.3. The multi-functional occlusion device according to claim 1 , wherein the retention screws present on the outer side of the said discs enable deployment through trans-venous (antegrade) or trans-arterial (retrograde) approach.4. The multi-functional occlusion device according to claim 1 , wherein the central geometrically shaped connector section connects the said proximal disc and distal disc to maintain the high-pressure disc in the high-pressure chamber of the heart and the low-pressure disc in the low-pressure chamber of the heart claim 1 , and provides hemodynamic adjustment.5. The multi-functional occlusion device according to and claim 1 , wherein the central geometrically ...

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Номер записи: 65
25-02-2016 дата публикации

PYLORIC OBSTRUCTION DEVICE

Номер: US20160051262A1
Автор: ALTMAN Nir, Fabian Izhak
Принадлежит:

An obstruction device includes an obstruction disc mounted on a shaft. The disc includes a membrane attached to a peripheral frame. An anchoring member extends from a distal portion of the shaft. The shaft, anchoring member and peripheral frame together have a unitary construction made from a bent slender element. 1. An obstruction device comprising:an obstruction disc mounted on a shaft, said disc comprising a membrane attached to a peripheral frame; andan anchoring member extending from a distal portion of said shaft, wherein said shaft is bent at a central bend point to form an arm that extends radially outwards from a central axis and which is then curved circumferentially about the central axis to form said peripheral frame.2. The obstruction device according to claim 1 , wherein said membrane is sealingly attached to said peripheral frame.3. The obstruction device according to claim 1 , wherein said shaft is made of a shape memory alloy.4. (canceled)5. The obstruction device according to claim 4 , wherein said arm is curved.6. The obstruction device according to claim 1 , wherein one or more ears extend from said peripheral frame.7. The obstruction device according to claim 1 , wherein said anchoring member has a crescent shape made of a distal curved portion claim 1 , round corners claim 1 , and round cusps.8. The obstruction device according to claim 1 , further comprising a delivery tube in which said obstruction device is disposed in a flattened configuration.9. The obstruction device according to claim 8 , further comprising an endoscope having a working channel in which said delivery tube and said obstruction device are mounted.10. The obstruction device according to claim 9 , comprising a pusher operative to push said anchoring member distally out of said delivery tube.11. A method comprising: 'an obstruction disc mounted on a shaft, said disc comprising a membrane attached to a peripheral frame, and an anchoring member extending from a distal portion ...

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Номер записи: 66
25-02-2021 дата публикации

DELIVERY SYSTEMS FOR CONTROL OF GASTROINTESTINAL BLEEDING

Номер: US20210052261A1
Автор: ENESTVEDT Brintha, MCCARTHY Simon J., PERRY Kenneth E., PERRY Kenneth P., Xie Hua
Принадлежит:

The present disclosure relates to a gastrointestinal delivery device of a dressing, where the delivery device is capable of fitting through a narrow channel before expanding and applying the dressing. The gastrointestinal delivery device may be used in all gastrointestinal bleeding applications and can be used with a biocompatible, foldable, thin profile, chitosan dressing. Various aspects of the device and its uses are provided herein. 1. A gastrointestinal delivery device comprising:an expandable support; anda releasable dressing;wherein the device is capable of fitting through a channel of 4 mm diameter or less.2. The gastrointestinal delivery device according to claim 1 , wherein the device is capable of fitting through one of: a channel of 3.8 mm diameter or less; a channel of 3.5 mm or less; or a channel of 3.2 mm or less.3. The gastrointestinal delivery device according to or claim 1 , wherein the releasable dressing attaches to the expandable support.4. The gastrointestinal delivery device according to any one of - claim 1 , wherein the device further comprises a sheath that envelopes the expandable support and the dressing.5. The gastrointestinal delivery device according to claim 4 , wherein the sheath constrains an expansion tension from the expandable support.6. The gastrointestinal delivery device according to any one of - claim 4 , wherein the expandable support is in an expanded format configuration.7. The gastrointestinal delivery device according to any one of - claim 4 , further comprising an axis connected to the expandable support.8. The gastrointestinal delivery device according to any one of - claim 4 , wherein the expandable support comprises an annular shape in an expanded format configuration.9. The gastrointestinal delivery device according to any one of - claim 4 , wherein the expandable support comprises a ribbon spring annular dressing support.10. The gastrointestinal delivery device according to any one of - claim 4 , wherein the ...

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Номер записи: 67
25-02-2021 дата публикации

Fixation devices, systems and methods for engaging tissue

Номер: US20210052274A1
Автор: Alfred H. Raschdorf, Eric A. Goldfarb, Ferolyn T. Powell, Jaime E. Sarabia, Jan Komtebedde, Kent D. Dell, Sylvia Wen-Chin Erickson
Принадлежит: Evalve Inc

System for fixation of leaflets of a heart valve including a delivery catheter having an elongated shaft, a proximal end portion and a distal end portion configured to be positioned proximate native leaflets of a heart valve from a remote vascular access point, the delivery catheter further includes a rotatable actuator rod having a threaded fastener at a distal end thereof, and a fixation device releasably coupled by a threaded connection to the threaded fastener of the actuator rod. The fixation device includes a first arm moveable between a closed position and an open position, a second arm moveable between a closed position and an open position. The fixation device further includes a first gripping element movable relative to the first arm in the open position, the first gripping element biased toward the first arm to capture a first leaflet of the heart valve therebetween, and a second gripping element movable relative to the second arm in the open position, the second gripping element biased toward the second arm to capture a second leaflet of the heart valve therebetween. The first gripping element and the second gripping element each includes a plurality of barbs extending therefrom, the plurality of barbs of each of the first gripping element and the second gripping element being aligned transversely in at least one row. The fixation device further includes a covering disposed on each of the first gripping element and the second gripping element, wherein the plurality of barbs of the first gripping element and the second gripping element, respectively, protrude through the covering.

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Номер записи: 68
23-02-2017 дата публикации

PERCUTANEOUS ATRIAL AND VENTRICULAR SEPTAL DEFECT CLOSURE DEVICE

Номер: US20170049425A1
Автор: Iaizzo Paul A., Rothstein Paul
Принадлежит:

Medical devices for closing anatomical apertures, such as atrial or ventricular septal defects, are disclosed. The medical devices can include a plug body having a proximal end, a distal end, and a longitudinal axis. The plug body can include an exterior surface, an interior surface defining an interior lumen, and a seal which can be located within the interior lumen. The medical devices can also include at least one arm member extending through the plug body between the exterior surface and the interior surface of the plug body. In certain embodiments, the medical device can include a distal loop and a proximal loop extending through the plug body. In certain embodiments, the proximal loop can be smaller than the distal loop, such that a top end and a bottom end of the proximal loop can fit within a top end and a bottom end of the distal loop. 116-. (canceled)17. A method of closing an anatomical aperture comprising:providing a delivery system for delivering a medical device for closing an anatomical aperture, the delivery system comprising a guide wire, a pushing tube, and a medical device comprising a plug body having a proximal end, a distal end, and an interior lumen along a longitudinal axis of the plug body, a seal located within the interior lumen, and a first pair of arm portions extending from the proximal end of the plug body and a second pair of arm portions extending from the distal end of the plug body;loading the medical device onto the guide wire;inserting the delivery system into a body lumen;advancing the guide wire through the body lumen to a deployment location within the anatomical aperture;pushing the medical device along the guide wire with the pushing tube through the body lumen to the deployment location; anddeploying the plug body of the medical device within the anatomical aperture such that the first pair of arm portions secure against tissue at the proximal end of the plug body and the second pair of arm portions secure against tissue at ...

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Номер записи: 69
22-02-2018 дата публикации

CLOSING DEVICE FOR TISSUE OPENINGS

Номер: US20180049731A1
Автор: Fearnot Neal E., Gittard Shaun Davis, Hadley Rita, Hardy Gregory James, Havel William J., JR. John C., McLawhorn Tyler E., Newkirk Jeremy T., Sherwinter Danny A., Sigmon, Surti Vihar C.
Принадлежит: Muffin Incorporated

There are shown and described embodiments of closure devices and systems for closing holes in tissue such as those caused unintentionally (e.g. hernia) or intentionally (e.g. openings in the right atrial appendage to access cardiac tissue). Such devices and systems include one or more mesh elements or anchors. In particular embodiments, a closure device includes first and second mesh closure members and a tether or stem connecting them. Embodiments of a delivery device for such closure devices are also described. 1. A closure for an opening in tissue , comprising:a first closure element, the first closure element having a first mesh enclosure, the first mesh enclosure having a first distal narrowed end and a second proximal narrowed end and a central volume, each of the first and second ends being inverted so as to be within the central volume of the first mesh enclosure, each of the first and second ends being surrounded by respective external surfaces of the first mesh enclosure;a second closure element, the second closure element having a second mesh enclosure physically separate from the first mesh enclosure, the second mesh enclosure having a third distal narrowed end and a fourth proximal narrowed end and a central volume, the third end being inverted so as to be within the central volume of the second mesh enclosure, each of the third and fourth ends being surrounded by respective external surfaces of the second mesh enclosure;a tether joining the first and second closure elements in an initial configuration prior to delivery of the closure elements to the opening, the tether having first and second enlarged ends, wherein the tether extends through at least the first narrowed end, parallel to and alongside the second narrowed end and into the second closure element, so that the first enlarged end of the tether is outside the first closure element adjacent or engaging the first end and the second enlarged end of the tether is within the central volume of the ...

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Номер записи: 70
26-02-2015 дата публикации

BRAIDED HEMOSTASIS SHAFT FOR IMPROVED TORSIONAL RESPONSE

Номер: US20150057703A1
Автор: GORST Oliver, Ryan Shawn, WILCOX Kevin John
Принадлежит:

A medical insertion device includes an elongated shaft extending from a proximal end to a distal end and having flexibility sufficient for insertion through a working channel of an endoscope along a tortuous path. The elongated shaft includes a coil extending from the proximal end to the distal end and having a channel extending longitudinally therethrough and a braided portion extending around a portion of the coil, the braided portion including a plurality of lines wound together such that first and second ones of the lines intersect to enclose a predetermined angle therebetween, the angle being between 25 and 55 degrees. 1. A medical insertion device , comprising: a coil extending from the proximal end to the distal end and having a channel extending longitudinally therethrough; and', 'a braided portion extending around a portion of the coil, the braided portion including a plurality of lines wound together such that first and second ones of the lines intersect to enclose a predetermined angle therebetween, the angle being between 25 and 55 degrees., 'an elongated shaft extending from a proximal end to a distal end and having flexibility sufficient for insertion through a working channel of an endoscope along a tortuous path, the elongated shaft including2. The medical insertion device of claim 1 , wherein the first one of the lines includes one of one claim 1 , two claim 1 , three and four filaments and the second one of the lines includes one of one claim 1 , two claim 1 , three and four filaments.3. The medical insertion device of claim 2 , wherein each of the lines contains the same number of filaments.4. The medical insertion device of claim 1 , wherein the braided portion includes eight lines wound together.5. The medical insertion device of claim 2 , wherein a diameter of filaments of the first one of the lines is the same as a diameter of filaments of the second one of the lines.6. The medical insertion device of claim 2 , wherein a diameter of filaments ...

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Номер записи: 71
03-03-2016 дата публикации

Closure Device and Methods and Systems for Using Same

Номер: US20160058434A1
Автор: DELALOYE Stéphane, HEFTI JEAN-LUC, PASSERINI REYNALD
Принадлежит:

Embodiments of the present disclosure are directed to apical closure systems, devices, and methods and systems for use thereof, for closing surgical openings or defects in the wall of the heart. 1. A closure device implantable via an access opening in the ventricle wall of a heart and operative to close the access opening , the device comprising:a support structure collapsible to a delivery state for implantation via the access opening, the support structure being self-expandable when released to expand to a deployed state in which the support structure defines at least (i) a first portion configured for positioning within the access opening, and (ii) a flange portion coupled to the first portion and configured for positioning substantially flat against the ventricle wall to prevent migration of the closure device in at least one direction following implantation; anda cover to at least partially cover the outer surface of the support structure.2. The closure device of claim 1 , wherein the flange portion is coupled to a distal portion of the first portion for bearing against the interior surface of the ventricle wall to prevent migration of the closure device in a direction out of the ventricle.3. The closure device of claim 1 , further comprising at least one protrusion to engage the ventricle wall for preventing migration of the closure device into the ventricle claim 1 , the protrusion being configured to project not more than between about 0.001 mm and about 2 mm from the exterior surface of the ventricle wall.4. The closure device of claim 3 , wherein the protrusion is configured to at least one of: (i) engage a portion of the ventricle wall inside the access opening; (ii) conform to the exterior surface of the ventricle wall; and (iii) comprise the proximal flange coupled to the first portion by a resilient coupling.5. The closure device of claim 1 , wherein the flange portion is coupled to a proximal portion of the first portion for bearing against the ...

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Номер записи: 72
03-03-2016 дата публикации

FILTER APPARATUS FOR OSTIUM OF LEFT ATRIAL APPENDAGE

Номер: US20160058539A1
Автор: Borillo Thomas E., Hauser Robert G., Holmes David, Schwartz Robert, Sutton Gregg S., VanTassel Robert A., Welch Jeffrey
Принадлежит: ATRITECH INC.

Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. 1. (canceled)2. A method of preventing atrial appendage thrombi from entering the blood stream comprising:piercing a wall of an atrial appendage with a distal tip of an atrial appendage anchor;securing a membrane over an ostium of the atrial appendage by extending the atrial appendage anchor through the wall of the atrial appendage and providing a tether between the atrial appendage anchor and the membrane,wherein the tether is adapted to hold the membrane snuggly against the ostium of the atrial appendage,further wherein the atrial appendage anchor is adapted to expand from the distal tip upon release thereby resisting being pulled from the wall of the atrial appendage.3. The method of claim 2 , wherein the membrane is adapted to be porous to blood and adapted to prevent thrombosis formed within the atrial appendage from leaving the atrial appendage.4. The method of claim 3 , wherein the membrane is adapted to be infiltrated with endothelial/endocardial cells thereby providing a nonthrombogenic surface.5. The method of claim 2 , wherein the membrane is adapted to be nonporous to blood and adapted to prevent thrombosis formed within the atrial appendage from entering the blood stream.6. The ...

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Номер записи: 73
04-03-2021 дата публикации

Occluder with access passage and closure thereof

Номер: US20210059650A1
Автор: Alex Bloomquist, Andrea Osberghaus, Brian Perszyk, Luann Raposo, Michael P. Meyer, Theodore P. Dale, Tracee Eidenschink
Принадлежит: St Jude Medical Cardiology Division Inc

The present disclosure is directed to embodiments of an occlusive medical device including a frame and at least one closure coupled to the frame. The frame includes a distal annular flange having a radially outer surface and a radially inner surface, a proximal annular flange having a radially outer surface and a radially inner surface, and a waist portion extending between and connecting the distal annular flange to the proximal annular flange. The radially inner surface of the distal annular flange, the waist member, and the radially inner surface of the proximal annular flange define an unobstructed passageway through the frame. The at least one closure is configured to close the passageway to: (i) provide an occlusive effect, and (ii) enable subsequent access through the passageway.

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Номер записи: 74
02-03-2017 дата публикации

DEVICES, SYSTEMS, AND METHODS FOR RESHAPING A HEART VALVE ANNULUS, INCLUDING THE USE OF MAGNETIC TOOLS

Номер: US20170055969A1
Автор: Chang Robert T., Machold Timothy R., RAHDERT DAVID A., Scott David, Tholfsen David R.
Принадлежит: MVRx, iNC.

Implants or systems of implants and methods apply a selected force vector or a selected combination of force vectors within or across the left atrium, which allow mitral valve leaflets to better coapt. The implants or systems of implants and methods make possible rapid deployment, facile endovascular delivery, and full intra-atrial retrievability. The implants or systems of implants and methods also make use of strong fluoroscopic landmarks. The implants or systems of implants and methods make use of an adjustable implant and a fixed length implant. The implants or systems of implants and methods may also utilize a bridge stop to secure the implant, and the methods of implantation employ various tools. 1. A method of establishing a pathway to a desired location within a body of a patient , the method comprising:providing a first elongate member extending along a longitudinal axis and having a first magnetically attracting element along a distal portion thereof;providing a second elongate member extending along a longitudinal axis and having a second magnetically attracting element along a distal portion thereof and an interior channel extending to a side hole in the distal portion;positioning the first elongate member at a first location within the body;positioning the second elongate member at a second location within the body adjacent the first location with a layer of tissue therebetween;aligning the distal portions of the first and second elongate member by magnetically coupling the first and second magnetically attracting elements on opposite sides of the layer of tissue; andpassing a piercing element between the first and second elongate elements through the layer of tissue and through the side hole of the second elongate member while magnetically coupled.2. The method of claim 1 , wherein aligning the distal portions comprises aligning the longitudinal axis of the distal portion of the first elongate member transverse to the longitudinal axis of the distal ...

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Номер записи: 75
15-05-2014 дата публикации

Percutaneous catheter directed intravascular occlusion device

Номер: US20140135828A1
Автор: John C. Oslund, Kurt Amplatz, Xiaoping Gu
Принадлежит: AGA Medical Corp

Embodiments of the present invention provide medical devices and methods for occluding a target site are provided. For example, the medical device may include a tubular member having proximal and distal ends and at least one plane of occlusion. The at least one plane of occlusion may be configured to substantially occlude the patent ductus arteriosus in less than about 1 minute. In addition or alternatively, the tubular member may consist of a single layer of material and be configured to be constrained within a catheter having an outer diameter of less than about 4 French for percutaneous delivery to the patent ductus arteriosus.

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Номер записи: 76
20-02-2020 дата публикации

Leadless pacemaker with collapsible anchoring device

Номер: US20200054882A1
Автор: Daniel Coyle, Paul A. Belk, Theodore Dale
Принадлежит: St Jude Medical Cardiology Division Inc

The present disclosure provides improved leadless pacemakers. In one embodiment, the leadless pacemaker includes an implantable pulse generator releasably coupled to a collapsible anchoring device. The collapsible anchoring device includes at least one pacing electrode configured to contact tissue at a target site.

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Номер записи: 77
28-02-2019 дата публикации

Patulous eustachian tube stent

Номер: US20190060125A1
Автор: Don Q. Ngo-Chu, Jetmir Palushi, Ketan P. Muni
Принадлежит: Acclarent Inc

A system effectively narrows a patulous Eustachian tube (ET) of a patient with a guide catheter, instrument, and insert. The guide catheter includes a shaft, a lumen and a distal end configured to provide access the ET when the guide catheter is inserted into a head of the patient. The instrument comprises a shaft. The insert comprises a body configured to radially expand and retract between a non-expanded state and an expanded state. The insert is sized and shaped to be received within the first lumen when in the non-expanded state and is operable to expand to the expanded state to substantially reduce an effective diameter of the ET.

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Номер записи: 78
27-02-2020 дата публикации

DEVICE AND METHOD FOR CONTROLLING IN-VIVO PRESSURE

Номер: US20200060825A1
Автор: ABA ZAKAY Avraham, BRAUN Ori J., Keren Gad, Rottenberg Dan, Rozy Yoram, Shmulewitz Ascher
Принадлежит: V-WAVE LTD.

A differential pressure regulating device is provided for controlling in-vivo pressure in a body, and in particularly in a heart. The device may include a shunt being positioned between two or more lumens in a body, to enable fluids to flow between the lumens, and an adjustable flow regulation mechanism being configured to selectively cover an opening of the shunt, to regulate the flow of fluid through the shunt in relation to a pressure difference between the body lumens. In some embodiments a control mechanism coupled to the adjustable flow regulation mechanism may be provided, to remotely activate the adjustable flow regulation mechanism. 1. A device for implantation within an atrial septum of a patient's heart to treat a heart condition , the device comprising:a shunt comprising flexible material and configured to transition between a collapsed delivery state and an expanded deployed state, the shunt further configured to engage an opening in the atrial septum in the expanded deployed state and defining a continuous opening in the atrial septum to permit passage of blood through the atrial septum via the shunt, the continuous opening having a cross-sectional area dependent on blood pressure differential across the atrial septum such that blood flow through the shunt changes responsive to change in the blood pressure differential across the atrial septum.2. The device of claim 1 , wherein the shunt is configured to permit passage of blood through the atrial septum to unload an excessive filling pressure of a left ventricle in a patient with congestive heart failure.3. The device of claim 1 , wherein the shunt comprises a flexible metal.4. The device of claim 3 , wherein the flexible metal comprises Nitinol.5. The device of claim 1 , wherein the shunt comprises a shape-memory material.6. The device of claim 1 , wherein the shunt is configured to self-expand from the collapsed delivery state and the expanded deployed state.7. The device of claim 1 , wherein the ...

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Номер записи: 79
08-03-2018 дата публикации

Occluder For Occluding An Atrial Appendage And Production Process Therefor

Номер: US20180064446A1
Автор: Figulla Hans-Reiner, Moszner Robert, Ottma Rüdiger, Schmidt Kathrin, Schräder R.
Принадлежит: OCCLUTECH HOLDING AG

An occlusion device and a production process for it are described. The occlusion device consists of a mesh or braiding of at least one wire or thread wherein the occlusion device has been given a suitable design using a reshaping and/or heat-treatment process, is self-expandable, and is configured for secure anchoring in an atrial appendage of the left or right atrium of a heart. The occlusion device comprises a proximal retention region on a proximal end of the occlusion device a distal retention region and a central region between the proximal retention region and said distal retention region and wherein the occlusion device has a closed distal end without a holder, and wherein the occlusion device is at least partly of essentially spherical form, and hollow. 1. (canceled)2. A method of occluding an atrial appendage , comprising:advancing a distal end of a delivery device to a left atrial appendage;exposing an occlusion device within the left atrial appendage;allowing said occlusion device to self-expand to a distal first enlarged portion and a proximal second enlarged portion, wherein the first enlarged portion and the second enlarged portion are connected by a reduced-diameter region that has a smaller expanded diameter than said first enlarged portion and said second enlarged portion; and,allowing said first enlarged portion and said second enlarged portion to move, via said reduced-diameter region, relative to each other to thereby accommodate movements of a heart.3. The method of claim 2 , wherein said allowing said occlusion device to self-expand further comprises positioning said occlusion device such that at least a portion of said reduced diameter portion is spaced apart from a wall of said left atrial appendage and an interspace is created between said reduced diameter portion and said wall.4. The method of claim 2 , wherein said allowing said occlusion device to self-expand further comprises creating an interspace between tissue of said left atrial ...

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Номер записи: 80
08-03-2018 дата публикации

Transseptal Puncture Apparatus and Method for Using the Same

Номер: US20180064915A1
Автор: Armour Andrew, Chanduszko Andrzej J., Devellian Carol A., Kurth Paul
Принадлежит:

Devices and methods for performing a transseptal puncture procedure using a device which includes either an untapered or tapered blunt end cannula disposed in an introducer carrying a sharp guidewire disposed longitudinally through the lumen of the blunt cannula, and a blunt end dilator wherein the guidewire is flexible and has an atraumatic shape at its tip. The cannula gives the more flexible introducer a defined shape and steerabilty allowing an ordinarily skilled physician to easily access a selected location on the septal wall of the heart for transseptal puncture and introducer placement thereacross without employing an exposed sharp end needle during the procedure. 1. A method comprising:telescopically disposing a blunt end cannula into a flexible introducer having an interior lumen, a distal curve, and a distal taper to define a predetermined shape and steerability to at least a distal portion of the introducer, where the flexible introducer has insufficient columnar strength and unsuitable shape for accessing a selected location on the cardiac septal wall of a patient's heart when the cannula is not disposed within the interior lumen of the introducer and in close proximity to the distal taper thereof, but is able to access the predetermined location on the cardiac septal wall when the cannula is disposed within the interior lumen of the introducer and in close proximity to the distal taper thereof;intravascularly accessing a right atrium of a patient's heart with the introducer;steering the distal taper of the introducer to the selected location on a septal wall of the heart to tent the septal wall at the selected location;advancing a sharp ended floppy guidewire telescopically disposed within an interior lumen of the cannula while being supported by the cannula to provide sufficient columnar strength to the floppy guidewire to allow it to be pushed through the septal wall into a left atrium of the patient's heart; andadvancing the sharp ended floppy ...

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Номер записи: 81
09-03-2017 дата публикации

DEVICES AND SYSTEMS FOR INVERTING AND CLOSING THE LEFT ATRIAL APPENDAGE

Номер: US20170065262A9
Автор: Kassab Ghassan S.
Принадлежит:

Devices, systems, and methods for inverting and closing the left atrial appendage. In at least one embodiment of a method for closing a left atrial appendage of the present disclosure, the method comprises the steps of inverting a distal portion of a left atrial appendage, and constraining the inverted distal portion of the left atrial appendage using a device configured to fit within an interior of the left atrial appendage. 1. A double stent assembly for occluding a left atrial appendage , the double stent assembly comprising:an outer scaffold configured for expansion and to be anchored within an interior of a left atrial appendage; andan inner scaffold positioned within the outer scaffold and configured for expansion within the outer scaffold and further configured to receive and engage a distal portion of the left atrial appendage after inversion of the distal portion of the left atrial appendage.2. The double stent assembly of claim 1 , wherein the double stent assembly is configured for placement upon a balloon coupled to a catheter.3. The double stent assembly of claim 1 , wherein the outer scaffold is configured for self-expansion within the interior of the left atrial appendage and further configured to conform to the interior of the left atrial appendage.4. The double stent assembly of claim 1 , further comprising:an occluder membrane coupled to the outer scaffold, the occluder membrane configured to occlude an orifice of the left atrial appendage upon expansion of the occluder membrane.5. The double stent assembly of claim 4 , wherein the occluder membrane is configured to prevent emboli from within the interior of the left atrial appendage from being released from the interior of the left atrial appendage.6. The double stent assembly of claim 4 , wherein the occluder membrane comprises a valve configured to receive a catheter therethrough.7. The double stent assembly of claim 6 , wherein the valve is a self-closing valve.8. The double stent assembly of ...

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Номер записи: 82
09-03-2017 дата публикации

Apical Closure System

Номер: US20170065263A1
Автор: Tuval Yossi
Принадлежит:

Aspects of the present invention provide apparatuses and methods for closing an apical hole in a heart of a subject, including a hole-closure device that includes a tissue-attachment portion configured to attach to cardiac tissue around the apical hole, and a collapsible portion coupled to the tissue-attachment portion and configured to close the hole by collapsing inwardly inside the apical hole. 123-. (canceled)24: An apparatus for closing a hole in tissue comprising:a tissue-attachment portion configured to attach to tissue around a hole;a ring-shaped collapsible portion coupled to the tissue-attachment portion and being at least partially formed from a shape-memory material to be configured to close the hole by collapsing inwardly to assume a collapsed state from an expanded state; anda sealing material disposed within an interior of the collapsible portion and configured to seal a center of the collapsible portion when the collapsible portion is in the collapsed state,wherein collapse of the collapsible portion causes collapse of the tissue attachment portion, and wherein collapse of the tissue-attachment portion is configured to draw tissue together and in conjunction with the sealing material disposed within the interior of the collapsible portion is configured to close the hole.25: The apparatus of claim 24 , wherein the tissue-attachment portion comprises a shape-memory alloy that is configured to assume a U-shape when the tissue-attachment portion is not constrained.26: The apparatus of claim 24 , wherein the tissue-attachment portion comprises a plurality of tissue-attachment elements.27: The apparatus of claim 24 , wherein the tissue-attachment portion comprises a plurality of hooks.28: The apparatus of claim 24 , wherein the tissue-attachment portion comprises:a first tissue-attachment portion configured to couple to tissue around a first side of the hole; anda second tissue-attachment portion configured to couple to tissue around a second side of the ...

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Номер записи: 83
09-03-2017 дата публикации

OCCLUSION DEVICE AND METHOD FOR ITS MANUFACTURE

Номер: US20170065264A1
Автор: Figulla Hans-Reiner, Krizanic Florian, Moszner Friedrich, Moszner Robert
Принадлежит: OCCLUTECH HOLDING AG

The present invention relates to an occlusion device () consisting of a braiding () of thin wires or threads () which is given a suitable form in a molding and heat treatment procedure. The occlusion device () has a proximal retention area () and a distal retention area (), whereby the ends of the wires or threads () converge into a holder () in distal retention area (). A cylindrical crosspiece () is furthermore disposed between the proximal and distal retention areas (). With the objective of providing an occlusion device which positions as flat as possible against the septum at the proximal side of a septal defect in the inserted state, the invention provides for the proximal retention area () of the braiding () to exhibit a completely closed proximal wall () disposed with a continuous surface at the proximal end of the occlusion device () which forms the proximal end () of said occlusion device (). 1. An occlusion device comprising a braiding comprising a plurality of thin wires or threads , said braiding having been given a suitable form in a molding and heat treatment procedure , having a proximal end portion , a distal end portion , and a crosspiece interposed between said proximal end portion and said distal end portion ,wherein the ends of each of the wires or threads converge at the distal end portion, each thread or wire originating in the distal end portion and extending to the proximal end portion before returning to the distal end portion; andwherein the proximal end portion consists of braiding free of discontinuities or ends of the plurality of thin wires or threads that results in a proximal wall having a continuous braided surface.2. The occlusion device according to claim 1 , wherein the proximal wall exhibits a curved surface as the continuous braided surface.3. The occlusion device according to claim 2 , wherein the curved surface conforms to the surface of a section of a ball-shaped claim 2 , bulb-shaped or teardrop-like body.4. The occlusion ...

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Номер записи: 84
11-03-2021 дата публикации

Conveyor for implant having at least one cavity

Номер: US20210068998A1
Автор: Anning Li, Shujun Li, SiYi Li
Принадлежит: Lifetech Scientific Shenzhen Co Ltd

A conveyor for an implant having at least one cavity, including a conveying handle, a conveying cable, and a core wire. The conveying cable is a tubular body, a proximal end of the core wire is connected to the conveying handle, and a distal end of the core wire penetrates a distal end of the conveying cable from a proximal end of the conveying cable; a first control is provided on the conveying handle, and when the implant is connected to the distal end of the conveying cable, the first control controls the distal end of the core wire to extend into the implant to straighten the curved implant, or the first control controls the core wire to withdraw from the implant to restore the implant to a preset shape. The conveyor can load and release the implant on the conveyor, and be used in the entire implanting process.

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Номер записи: 85
17-03-2016 дата публикации

MEDICAL MATERIAL

Номер: US20160074023A1
Автор: KAWADA Noriko, Nakayama Hidetaka, SAKAMOTO Yuki, TAKI Kensuke
Принадлежит: GUNZE LIMITED

There is provided a defect hole closing material which achieves minimally invasive medical treatment for Atrial Septal Defect, and poses little possibility of occurrence of a failure in the body in some distant future. 1. A medical material which comprises a cylindrical body of mesh-like structure made of a filamentary material , and has a configuration such that a cylinder diameter of a substantially central section of said cylindrical body is made smaller than a cylinder diameter of other section of said cylindrical body by constricting said substantially central section.2. The medical material according to claim 1 ,wherein said configuration is defined by an hourglass shape, a numeral “8” shape, or a double spindle shape.3. The medical material according to claim 1 ,wherein said filamentary material is a bioabsorbable material.4. The medical material according to claim 1 ,wherein a porous cylindrical layer, which is composed of any one of a nonwoven cloth, a sponge, a film, and a composite of them that are made of a bioabsorbable material, is placed on an inner surface of said cylindrical body.5. The medical material according to claim 1 ,wherein the cylinder diameter of said other section can be increased by, while securely holding a first end which is one end of said medical material in a direction of length of the cylindrical body, pulling a second end, which is the other end of said medical material, toward the first end.6. The medical material according to claim 5 , further comprising:a string which is passed into said cylindrical body so as to be directed to and engage with said second end, and then run up to said first end.7. The medical material according to claim 1 ,wherein, with respect to said substantially central section serving as a center, there are provided a first cylindrical section located toward the first end and a second cylindrical section located toward the second end,and wherein said first cylindrical section and said second cylindrical ...

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Номер записи: 86
17-03-2016 дата публикации

Surgical device for closure of atrial septal defect with minimally invasive approach

Номер: US20160074026A1
Автор: Ali Namazi, Farideh Roshanali, Seyed Nasser Pourmoosavi
Принадлежит: Individual

A method of providing a surgical device for closure of Atrial Septal Defect (ASD) with minimally invasive approach includes a head portion that includes a distal jaw being distal relative to a person holding the surgical device, a guide rod which drives the distal jaw, and a plurality of first suture-guide channels attached to the distal jaw, and a body portion which is stationary and includes a cylindrical base, a proximal jaw attached to the cylindrical base, and a plurality of second suture-guide channels attached to the proximal jaw. A lever drives the distal jaw away from the proximal jaw such that the distal jaw and the proximal jaw are spaced on different sides of an ASD hole. After a suture thread sutures a pericardium patch, the lever pulls the distal jaw backward toward the proximal jaw such that the first suture-guide channels couple with the second suture-guide channels.

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Номер записи: 87
15-03-2018 дата публикации

IMPLANTABLE SEALING DEVICE

Номер: US20180070934A1
Автор: Osypka Peter
Принадлежит:

An implantable sealing device is disclosed herein and includes an elongated elastic member having distal and a proximal ends, at least one sealing element including braiding having outside and inside faces. The braiding can include of a plurality of fine threads of a memory metal alloy and wherein at least one face of the braiding is coated by a membrane. The braiding can also include a fixing member positioned at one of the distal and proximal ends of the elastic member and being positioned opposite to the braiding. 1. A method for sealing a tissue opening , especially a trocar tube opening in a myocardium at an apex of a left ventricle comprising the steps of: an elongated elastic member having a distal and a proximal end;', 'at least one sealing element comprising a braiding extending radially from the elongated elastic member having outside and inside faces, the braiding being positioned respectively at one of the distal and proximal ends of the elastic member, wherein the braiding includes a plurality of fine threads of a memory metal alloy and wherein at least one face of the braiding is coated by a membrane; and', 'a fixing member being positioned respectively at the distal and proximal ends of the elastic member and being positioned opposite to the braiding;, "inserting a trocar tube including a folded sealing device and guiding the trocar tube through an opening in a myocardium into a patient's left ventricle, the sealing device comprising:"}pushing the braiding out of the trocar tube so that the umbrella moves from a folded position into a deployed position whereas the fixing member remains inside the trocar tube;stretching the elastic member by means of a tensioning cord and pulling the pre-stretched elastic member out of the opening in a myocardium whereby the fixing member is placed against a tissue of a myocardium and moves from a folded position into a deployed position;removing the trocar tube whereby the elastic member remains stretched; andremoving ...

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Номер записи: 88
07-03-2019 дата публикации

TISSUE ANCHORS WITH HEMOSTASIS SEAL

Номер: US20190069891A1
Автор: Campbell Thomas, DENTI Paolo, GILMORE Michael, GUIDOTTI Andrea, LYNN Kevin, MULLINS John, Murphy Charlotte, VANERMEN Hugo
Принадлежит: 4TECH INC.

A tissue anchor is provided that is configured to be delivered in a constrained state within a deployment tool. The tissue anchor includes a shaft and a tissue-coupling element, which (a) extends from a distal end of the shaft, and (b) is configured to be advanced through a heart wall and be coupled to a far side of the heart wall. The tissue anchor further includes a sealing element, which is (a) disposed around the shaft, (b) sized and shaped to be disposed entirely within the heart wall, and (c) configured to promote hemostasis. Other embodiments are also described. 158-. (canceled)59. A tissue anchor configured to be delivered in a constrained state within a deployment tool , the tissue anchor comprising:a shaft;a tissue-coupling element, which (a) extends from a distal end of the shaft, and (b) is configured to be advanced through a heart wall and be coupled to a far side of the heart wall; anda sealing element, which is (a) disposed around the shaft, (b) sized and shaped to be disposed entirely within the heart wall, and (c) configured to promote hemostasis.60. The tissue anchor according to claim 59 , wherein the tissue anchor further comprises a distal collar disposed around the shaft proximal to the distal end of the shaft.61. The tissue anchor according to claim 60 , wherein the sealing element is disposed proximal to the distal collar.62. The tissue anchor according to claim 61 , wherein the sealing element is disposed in contact with the distal collar.63. The tissue anchor according to claim 60 , wherein the tissue anchor further comprises a proximal collar disposed around the shaft proximal to the distal collar.64. The tissue anchor according to claim 63 , wherein the sealing element is disposed proximal to the distal collar and distal to the proximal collar.65. The tissue anchor according to claim 60 , wherein the sealing element comprises a sleeve that covers the distal collar.66. The tissue anchor according to claim 59 , wherein the sealing element ...

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Номер записи: 89
07-03-2019 дата публикации

LEFT ATRIAL APPENDAGE OCCLUDER DEVICE ANCHORING SYSTEM, ANCHOR, AND METHOD OF ATTACHMENT

Номер: US20190069901A1
Автор: Forbes Thomas J.
Принадлежит:

The present invention relates in general to anchoring systems for occluder devices, and more specifically, to an anchoring system and method for implanting an occluder device within a left atrial appendage (“LAA”) of the heart. The anchoring system is configured so that an anchor penetrates the inner endocardium layer, middle myocardium layer, and outer epicardium layer of an LAA wall. The purpose of the present invention is to provide an occluder device anchor that has a low risk of embolization and/or causing injury to neighboring valve structures. An additional purpose of the present invention is to provide an anchoring system and method for implanting an occluder device within the LAA that allows for the occluder device to be retrievable after initial placement, reusable, and repositionable for an optimal final placement within the LAA. 1. An anchoring system for implanting an occluder device within a left atrial appendage (LAA) of a heart , comprising:an outer sheath;a delivery catheter;a LAA occluder device configured to occlude the LAA of a heart to prevent blood from pooling, collecting and forming blood clots in the LAA during atrial fibrillation to reduce the risk of stroke;an anchor comprising a first half, an opposite second half and a shaft connecting the first half to the second half;a contracted first position of the anchor;a deployed second position of the anchor;the outer sheath configured to be inserted into the LAA through a left atrium proper of the heart;the delivery catheter configured to be advanced through the outer sheath into the LAA;the delivery catheter configured to perforate an inner endocardium layer, middle myocardium layer, and outer epicardium layer of an LAA wall of the heart;the delivery catheter configured to create a small hole through the inner endocardium layer, middle myocardium layer, and outer epicardium layer of the LAA wall into a pericardial space;the delivery catheter configured to be removed from the LAA through the ...

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Номер записи: 90
23-03-2017 дата публикации

Wound Occlusion Device

Номер: US20170079632A1
Автор: Plass André
Принадлежит:

Novel wound occlusion devices (′) and methods for the acute treatment of massively bleeding external wounds are suggested. The novel devices which are insertable into wounds W are characterised by a base element (′); a sealing element () and a release mechanism of the sealing element (). The sealing element () comprises a frame element () and a layer element () and is transformable between a contracted and an expanded configuration (′) by the release mechanism. The sealing element () has in the expanded configuration (′) a shape adaptable to the shape of the wound W and forms a form-locked and/or force-locked connection with the wound W thereby occluding the wound and effectively stopping blood loss. 1. A wound occlusion device insertable into a wound W , comprising:a base element;a sealing element; anda release mechanism of the sealing element,wherein the sealing element comprises a frame element and a layer element, and the sealing element is transformable between a contracted and an expanded configuration by the release mechanism, and wherein the sealing element has in the expanded configuration a shape adaptable to the shape of a wound W, forming a form-locked and/or force-locked connection with the wound W, the form-locked and/or force-locked connection of the sealing element with the wound W providing an occlusion function.2. The wound occlusion device according to claim 1 , wherein the frame element of the sealing element is selected from the group consisting of a wire coil claim 1 , a wire mesh claim 1 , and a wire braiding.3. The wound occlusion device according to claim 1 , wherein the frame element of the sealing element is made of or comprises a shape-memory material claim 1 , preferably Nitinol.4. The wound occlusion device according to claim 1 , wherein the layer element is made of and/or covered by a material selected from the group consisting of a blood-proof material claim 1 , a water-proof material claim 1 , a haemostatic material claim 1 , an ...

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Номер записи: 91
23-03-2017 дата публикации

Castle-key clip for securing closed diverticula

Номер: US20170079654A1
Автор: Sam Malanowski, Todd Dickson
Принадлежит: EMPIRE TECHNOLOGY DEVELOPMENT LLC, SPARK MEDTECH DEVELOPMENT LLC

Several embodiments disclosed herein relate to apparatus, methods, and systems for treating a diverticulum. In some examples, disclosed is a clip for treating diverticulum. The clip can include a plurality of petals, points, and keys. Each of petals can include a curved portion, a first arm, and a second arm. A portion of the first arm of each petal can be flexibly interconnected to a portion of the second arm of another petal. The points can be formed by an end of the first arm of one of the petals and an end of the second arm of another of the petals. The petals can form a circular configuration. The keys can be attached to the curved portion of each of the petals and each of the keys can interact with a delivery device for maintaining the clip on the delivery device.

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Номер записи: 92
12-03-2020 дата публикации

Expandable Mesh with Locking Feature

Номер: US20200078157A1
Автор: JR. John C., McLawhorn Tyler E., Sigmon
Принадлежит: Cook Medical Technologies LLC

The present embodiments provide an expandable mesh comprising a first coupling element, a second coupling element, and an intermediate portion disposed between the first coupling element and the second coupling element. Proximal retraction of the first coupling element relative to the second coupling element causes the intermediate portion to flare out to an enlarged width. In one embodiment, the first coupling element comprises a first tube and the second coupling element comprises a second tube. 120-. (canceled)21. A method for manufacturing an expandable mesh , the method comprising:providing a mesh material having first and second regions;treating the mesh material to form a first coupling element at the first region of the mesh material,wherein the first coupling element is initially located proximal to the second region of the mesh material;everting the mesh material such that the second region of the mesh material is disposed proximal to the first coupling element; andtreating the mesh material to form a second coupling element at the second region, wherein an intermediate portion is disposed between the first coupling element and the second coupling element,wherein proximal retraction of the first coupling element relative to the second coupling element is adapted to cause the intermediate portion to flare out to an enlarged width.22. The method of claim 21 , wherein the first coupling element comprises a first tube claim 21 , and wherein the second coupling element comprises a second tube.23. The method of claim 22 , wherein at least one of the first tube or the second tube is formed by melting or heat-shrinking the mesh material.24. The method of claim 22 , wherein the expandable mesh comprises a delivery state in which the first and second tubes lack an axial overlap claim 22 , and further comprises an expanded state in which the first and second tubes at least partially axially overlap.25. The method of claim 22 , wherein a distal end of the first tube ...

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Номер записи: 93
25-03-2021 дата публикации

DEVICES AND METHODS FOR CLOSING A LEFT ATRIAL APPENDAGE

Номер: US20210085302A1
Автор: Rowe Stanton J., Schwartz Robert S.
Принадлежит:

Using a delivery system, a disk is introduced into a left atrium (LA) of a heart of a subject. The left atrial appendage (LAA) is everted into the LA by, the from within the LAA, grasping tissue of the LAA, and pulling the LAA through an ostium of the LAA and into the LA. Within the LA, the disk is expanded, and the perimeter of the everted LAA is sandwiched between a periphery of the disk and the wall around the ostium such that the everted LAA covers the ostium. The everted LAA is secured covering the ostium by anchoring the periphery of the disk around the perimeter of the everted LAA. Other embodiments are also described. 1. A method for use at a left atrial appendage (LAA) of a heart of a subject , the heart having a left atrium (LA) having a wall that defines an ostium that provides fluid communication between the LA and the LAA , the method comprising:using a delivery system, transluminally introducing a disk into the LA;everting the LAA into the LA by, the from within the LAA, grasping tissue of the LAA, and pulling the LAA through the ostium and into the LA; and flattening the everted LAA such that the flattened everted LAA defines a perimeter that circumscribes the ostium;', 'expanding the disk;', 'sandwiching the perimeter of the flattened everted LAA between a periphery of the disk and the wall around the ostium such that the flattened everted LAA covers the ostium; and', 'securing the flattened everted LAA covering the ostium by anchoring the periphery of the disk around the perimeter of the flattened everted LAA., 'within the LA2. The method according to claim 1 , wherein expanding the disk comprises laterally expanding the everted LAA by expanding the disk.3. The method according to claim 1 , wherein the delivery system includes a sheath claim 1 , and wherein expanding the disk comprises retracting the sheath claim 1 , allowing the disk to expand.4. The method according to claim 1 , wherein anchoring the periphery of the disk around the perimeter of ...

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Номер записи: 94
21-03-2019 дата публикации

SINUS VENOSUS ATRIAL SEPTAL DEFECT TREATMENT DEVICE

Номер: US20190083076A1
Автор: ALANBAEI Muath
Принадлежит:

Devices and methods for treating a sinus venosus atrial septal defect. A treatment device may have a tubular shape and may be configured to be arranged to provide a conduit between an upper right pulmonary vein (PV) and a left atrium (LA). The device may have a proximal portion comprising a flexible mesh configured to anchor within the LA, a distal portion comprising a flexible mesh configured to anchor within the target PV, and a central portion having a plurality of elongate parallel bars. A method for treating a sinus venosus atrial septal defect may include percutaneously advancing the device through the femoral vein and inferior vena cava (IVC), and into the right atrium (RA). The method may include creating a trans-septal opening, passing the device through the opening into the LA, and toward the upper right PV to treat the defect. 1. A device for treating a sinus venosus atrial septal defect , the device comprising a hollow lumen extending between first and second open ends , the lumen defined by a cylindrical sidewall and comprising:a proximal portion arranged at the first open end and comprising a self-expanding mesh, the proximal portion sized and configured to be arranged within a left atrium, the proximal portion further configured to anchor to a wall of the left atrium;a distal portion arranged at the second end and comprising a self-expanding mesh, the distal portion sized and configured to be arranged within a pulmonary vein, the distal portion further configured to anchor to a wall of the pulmonary vein; anda central portion extending between the proximal and distal portions, the central portion comprising a plurality of elongate parallel bars surrounded by a coating, wherein the central portion is sized and configured to be arranged within a right atrium, and to provide a conduit for blood flow between the pulmonary vein and the left atrium.2. The device of claim 1 , wherein the proximal portion is configured to expand to a bell-shaped skirt claim 1 ...

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Номер записи: 95
21-03-2019 дата публикации

Tissue Anchors with Hemostasis Seal

Номер: US20190083085A1
Автор: Campbell Thomas, DENTI Paolo, GILMORE Michael, GUIDOTTI Andrea, LYNN Kevin, MULLINS John, Murphy Charlotte, VANERMEN Hugo
Принадлежит: 4TECH INC.

Apparatus for use with a deployment tool is provided. The apparatus includes a tissue anchor configured to be delivered in a constrained state within the deployment tool. The tissue anchor includes a shaft and a tissue-coupling element, which extends from a distal end of the shaft and is configured to be advanced through an incision in a wall of a cardiac chamber and be coupled to a far outer side of the wall. A spring is disposed proximal to a sealing element, and is configured to distally push the sealing element against an inner side of the wall to seal the incision. Other embodiments are also described. 1. Apparatus for use with a deployment tool , the apparatus comprising:a tissue anchor configured to be delivered in a constrained state within the deployment tool, the tissue anchor comprising a shaft and a tissue-coupling element, which extends from a distal end of the shaft and is configured to be advanced through an incision in a wall of a cardiac chamber and be coupled to a far outer side of the wall;a sealing element; anda spring, which is disposed proximal to the sealing element, and which is configured to distally push the sealing element against an inner side of the wall to seal the incision.2. The apparatus according to claim 1 , wherein the sealing element is disposed around a portion of the shaft.3. The apparatus according to claim 1 , wherein the spring is disposed around a portion of the shaft.4. The apparatus according to claim 1 , wherein the sealing element is annular.5. The apparatus according to claim 1 , further comprising a flexible elongate tension member fixed to the tissue-coupling element claim 1 , wherein the flexible elongate tension member passes through the seal and the spring.6. The apparatus according to claim 5 , wherein the tissue-coupling element comprises a wire claim 5 , and wherein the flexible elongate tension member is fixed to the wire.7. The apparatus according to claim 1 , further comprising one or more tethers coupled to ...

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Номер записи: 96
02-04-2015 дата публикации

VASCULATURE CLOSURE DEVICES AND METHODS

Номер: US20150094759A1
Автор: Ben-Yosef Alon, Penner Abraham, Wolinsky Lone
Принадлежит:

Vasculature closure devices, and systems and methods for their use, are provided. In one embodiment, the vasculature closure device includes an expandable support frame deployable within a vessel, a sealing membrane at least partially supported by the support frame, and a cross-member support extending across at least a portion of the sealing membrane. Upon expanding the support frame, the device is configured to intraluminally position the sealing membrane against a puncture site existing in a wall of the vessel. The cross-member support includes a flexible wire coupled to the sealing membrane at an intermediate portion of the flexible wire and configured to maintain the sealing membrane against the puncture site. 1. A vasculature closure device , comprising:an expandable support frame deployable within a vessel;a sealing membrane at least partially supported by the support frame; anda cross-member support extending across at least a portion of the sealing membrane;wherein, upon expanding the support frame, the device is configured to intraluminally position the sealing membrane against a puncture site existing in a wall of the vessel;wherein the cross-member support comprises a flexible wire configured to maintain the sealing membrane against the puncture site; andwherein the flexible wire comprises a first wire segment and a second wire segment defining an X-shape of the cross-member support and configured to distribute forces applied to the cross-member support.2. The vasculature closure device of claim 1 , wherein the flexible wire is attached to opposite sides of the support frame.3. The vasculature closure device of claim 1 , wherein the flexible wire is formed of a suture material.4. The vasculature closure device of claim 1 , wherein the flexible wire extends over the sealing membrane and is configured to be positioned between the sealing membrane and the wall of the vessel.5. The vasculature closure device of claim 1 , wherein the flexible wire extends ...

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Номер записи: 97
19-03-2020 дата публикации

Method and Apparatus For Intraluminally Occluding Hollow or Tubular Body Structures

Номер: US20200085443A1
Автор: Miller Arnold, Miller Raanan
Принадлежит: Amsel Medical Corporation

Catheter-based devices and methods for endoluminally accessing and occluding hollow anatomical structures are disclosed. Occlusion clips are contained in one or more needles that pierce opposing walls of the anatomical structure to deploy the clips externally of the structure. The clips then are drawn together to press the opposing anatomical walls together. 1. Apparatus for endoluminally occluding at least a portion of a hollow mammalian anatomical structure having opposing walls , the walls each having an inner surface and an outer surface , the apparatus comprising:a catheter having proximal and distal ends and advanceable through a natural body lumen to the hollow anatomical structure, the catheter having two catheter lumens open at the distal region of the catheter, each lumen containing a needle having an outlet, each needle containing an occlusion clip, each clip being configurable from a low-profile configuration containable within the needle to a deployed, larger-profile configuration when released from the needle;the needles being extendable from the distal ends of their catheter lumens to pierce opposing walls of the anatomical structure and locate the needle outlets exteriorly of the anatomical structure;a clip pusher associated with each occlusion clip and movable within its associated needle to push the clips out of the needle outlets while the distal tips of the needles are located exteriorly of the walls of the anatomical structure, thereby deploying the clips on opposite sides of the anatomical structure;at least one cord connecting the clips and being manipulable to draw the clips toward each other after the clips have been released from the needles to clamp the opposing walls of the anatomical structure between the clips; andmeans for securing the clips in their tissue-clamping configuration.2. The apparatus as defined in wherein each clip is expandable from its low profile to its enlarged profile after release from the needles.3. The apparatus as ...

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Номер записи: 98
05-04-2018 дата публикации

PATENT FORAMEN OVALE (PFO) CLOSURE DEVICE WITH LINEARLY ELONGATING PETALS

Номер: US20180092634A1
Автор: Callaghan David J.
Принадлежит:

The present invention provides a device for occluding an anatomical aperture, such as an atrial septal defect (ASD) or a patent foramen ovale (PFO). The occluder includes two sides connected by a central tube. In some embodiments, the occluder is formed from filaments that are joined together to define a substantially cylindrical form with openings defining struts. Upon the application of force, the struts deform into loops. The loops may be of various shapes, sizes, and configurations, and, in at least some embodiments, the loops have rounded peripheries. The occluder further includes a catch system that maintains its deployed state in vivo. When the occluder is deployed in vivo, the two sides are disposed on opposite sides of the septal tissue surrounding the aperture and the catch system is engaged so that the occluder closes the aperture. 131.-. (canceled)32. A device for occluding a defect in a body and having a delivery configuration and a deployed configuration , the occluder comprising: {'b': 2', '2', '2, 'a proximal end portion, p a distal end portion, p a central portion, and p struts extending joined to the proximal end portion, the distal end portion, and the central portion forming a proximal occlusive element having overlapping petals and a distal occlusive element having overlapping petals in the deployed configuration.'}, 'an occluder body formed from a cut-tube and including33. The device of claim 32 , wherein one end of each of the petals of the proximal occlusive element and the distal occlusive element originates from the central portion.34. The device of claim 32 , wherein the proximal end portion claim 32 , the central portion claim 32 , and the distal end portion are generally coaxially aligned with a longitudinal axis of the occluder body in the deployed configuration and in the delivery configuration.35. The device of claim 32 , wherein the proximal end portion claim 32 , the central portion claim 32 , and the distal end portion each include ...

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Номер записи: 99
12-04-2018 дата публикации

Device, Kit And Method For Closure Of A Body Lumen Puncture

Номер: US20180098759A1
Автор: Jonsson Anders
Принадлежит: ITSO Medical AB

A medical device and method for closure of a puncture in a body lumen are disclosed. The device has an aggregate () of a support structure () and a substantially fluid tight patch member () attached thereto at an attachment unit (). The aggregate has a first, temporary delivery shape, for delivery to an interior of said body lumen and to be subsequently subjected to a change of shape to a second shape, which is a tubular shape. When delivered in said body lumen, the patch member is arranged radially outside of said tubular support structure and arranged towards an inner tissue wall of the body lumen. The aggregate is the detached from a delivery device and said puncture is intraluminally closed in a leakage tight manner, advantageously supported by a physiological pressure of a body fluid in said body lumen. The device may biodegrade over time. 1an elongate delivery unit having a distal end; and an aggregate ofa support structure having a first shape, which is a temporary delivery shape, for delivery to an interior of said body lumen through said puncture and to be subsequently controllably subjected to a change of shape to a second shape, which is a tubular shape, when delivered in said body lumen, anda patch member attached to said support structure at an intermediate portion between two opposite ends thereof; whereinsaid distal end of said elongate delivery unit is radially releasably attached to said aggregate at an attachment position intermediate between ends of said patch member and detachable therefrom upon deployment of said aggregate in said body lumen;wherein said patch member is sized and shaped for arranging it towards an inner tissue wall of said body lumen at a site of said puncture of said body lumen and extending over a puncture opening, andwherein said delivery unit extends in a direction radially from said aggregate through said opening, such that said puncture is controllably sealed off by said patch when drawing said delivery device in a ...

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Номер записи: 100