System and method for transapical access and closure

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1. A system for providing surgical access across a wall of a tissue structure , comprising:a. a delivery member having proximal and distal ends;b. a plurality of helical members, each having proximal and distal ends and a helical shape, each proximal end coupled to the delivery member distal end, each distal end extending distally of the delivery member distal end;c. a plurality of anchor members removably coupled to the helical member distal ends; andd. a plurality of suture members coupled distally to a portion of one of the anchor members and extending proximally to a position wherein at least a portion of each may be freely manipulated by an operator;wherein upon rotation of the delivery member in a first direction, the helical members and coupled anchor members are advanced across at least a portion of the wall of the tissue structure, pulling along the distal portions of the suture members in a deployed suture pattern which remains coupled to the anchor member.2. The system of claim 1 , wherein the deployed suture pattern is characterized in that in the aggregate it represents a number of helical loops encapsulated by the wall of the tissue structure that is greater than about one and one-half helical loops claim 1 , and is less than about four helical loops.3. The system of claim 2 , wherein the deployed suture pattern is characterized in that in the aggregate it represents a number of helical loops encapsulated by the wall of the tissue structure that is greater than about one and ...

System and method for safety syringe

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior. 1. A system for serially injecting liquids , comprising:a syringe body defining a syringe proximal opening and a distal needle interface at a distal end thereof;proximal and distal stopper members disposed in the syringe body, forming a proximal chamber between the proximal and distal stopper members and a distal chamber between the distal stopper member and the distal end of the syringe body;a first liquid in the distal chamber;a second liquid in the proximal chamber; a needle retention feature disposed in the plunger interior,', 'an energy-storage member disposed in the plunger interior, and', 'an energy-storage member latching member disposed in the plunger interior; and, 'a plunger member defining a plunger interior and configured to be manually manipulated to insert the proximal stopper member distally relative to the syringe body, the plunger member including'} a needle having a needle proximal end feature,', 'a hub, and', 'a needle latching member configured to couple the needle to the hub,, 'a needle hub assembly coupled to the distal needle interface ...

System and method for transapical access and closure

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1a. a delivery member having proximal and distal ends;b. a first helical member having proximal and distal ends and a helical shape, the proximal end coupled to the delivery member distal end, the distal end extending distally from the delivery member distal end;c. an anchor member removably coupled to the helical member distal end;d. a suture member coupled distally to a portion of the anchor member and extending proximally to a position wherein at least a portion of it may be freely manipulated by an operator; ande. an elongate instrument at least partially inserted through the first helical member;wherein upon rotation of the delivery member in a first direction, the first helical member and coupled anchor member are advanced across at least a portion of the wall of the tissue structure, pulling along the distal portion of the suture member in a deployed suture pattern which remains coupled to the anchor member, the deployed suture pattern being characterized in that it represents a number of helical loops encapsulated by the wall of the tissue structure that is greater than about one and one-half helical loops, and is deployed in a substantially helical configuration selected to movably accommodate the elongate instrument therethrough.. A system for providing surgical access across a wall of a tissue structure, comprising: This application is a continuation of U.S. patent application Ser. No. 13/725,916 filed on Dec. 21, 2012, which is a continuation of U.S. patent application Ser. No. ...

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body. 1. A system for mixing drug products and injecting , comprising:a syringe body defining a proximal opening and a distal needle interface at a distal end thereof;proximal and distal stopper members disposed in the syringe body, forming a proximal drug chamber between the proximal and distal stopper members and a distal drug chamber between the distal stopper member and the distal end of the syringe body; a needle retention feature disposed in the plunger interior,', 'an energy-storage member disposed in the plunger interior, and', 'an energy-storage member latching member disposed in the plunger interior; and, 'a plunger member defining a plunger interior and configured to be manually manipulated to insert the proximal stopper member relative to the syringe body, the plunger member including'} a needle having a needle proximal end feature,', 'a hub, and', 'a needle latching member configured to couple the needle to the hub,, 'a needle hub assembly coupled to the distal needle interface of the syringe body, the needle assembly including'}wherein first and second ...

SYSTEM AND METHOD FOR SAFETY SYRINGE

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber. 1. A system for injecting , comprising:a. a syringe body defining an interior medicine chamber and a distal needle interface;b. a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber;c. a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; andd. a needle having proximal and distal ends, the proximal end being removably coupled to the distal needle interface of the syringe body and at least partially retractable into the interior medicine chamber upon manipulation of the plunger member relative to the syringe body to transform a plunger latching member from a latched state to an unlatched state, the plunger latching member intercoupled between the syringe body and the plunger member;wherein the plunger latching member is substantially disposed within a lumen defined by the plunger member.2. The system of claim 1 , wherein the syringe body comprises an off-the-shelf syringe body.3. The system of claim 1 , wherein the syringe body comprises a generally cylindrical geometry.4. The system of claim 1 , wherein the medicine chamber is configured to contain between about 0.5 cc and about 5 cc of medicine.5. The system of claim 4 , wherein the medicine ...

System and method for safety syringe

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.

System and method for safety syringe

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

INJECTION SYSTEM AND METHOD

An injection system includes a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the syringe body, forming respective proximal and distal drug chambers. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the syringe body. Moreover, the system includes a fluid conveying assembly including a penetrating member configured to penetrate the distal stopper member to fluidly couple the proximal and distal drug chambers, a distal exit tube, and a transfer member disposed at least partially around a portion of the penetrating member and defining a fluid passage. A distal end of the penetrating member is disposed in the distal exit tube. 1. An injection system , comprising:a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof;proximal and distal stopper members disposed in the syringe body, forming a proximal drug chamber between the proximal and distal stopper members and a distal drug chamber between the distal stopper member and the distal end of the syringe body;a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the syringe body; and a penetrating member configured to penetrate the distal stopper member to fluidly couple the proximal and distal drug chambers,', 'a distal exit tube, wherein a distal end of the penetrating member is disposed in the distal exit tube, and', 'a transfer member disposed at least partially around a portion of the penetrating member, wherein the distal transfer member defines a fluid passage., 'a fluid conveying assembly comprising'}2. The system of claim 1 , wherein the transfer member comprises a sleeve disposed on the portion of the penetrating member.3. The system of claim 2 , wherein the sleeve ...

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior. 1. A system for serially injecting liquids , comprising:a syringe body defining a syringe proximal opening and a distal interface at a distal end thereof;proximal and distal stopper members disposed in the syringe body, forming a proximal chamber between the proximal and distal stopper members and a distal chamber between the distal stopper member and the distal end of the syringe body;a first liquid in the distal chamber;a second liquid in the proximal chamber;a plunger member configured to be manually manipulated to insert the proximal stopper member distally relative to the syringe body; and a transfer pipe having a transfer pipe proximal end and a transfer pipe distal end,', 'a hub, and', 'a connector fluidly coupled to the transfer pipe distal end,, 'a hub assembly coupled to the distal interface of the syringe body, the hub assembly including'}wherein manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid from the distal chamber through thetransfer pipe, then serially ...

SYSTEM AND METHOD FOR SAFETY SYRINGE

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member. 1. A method for preparing a pre-filled multi-chamber injection system , the method comprising:providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end;introducing a first substance into a distal end of the body interior;disposing a distal stopper member in the body interior through the open proximal end of the injection system body, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior, wherein the first substance is disposed in the distal chamber;introducing a second substance into the body interior;disposing a proximal stopper member in the body interior through the open proximal end of the injection system body, such that the proximal stopper member defines a proximal end of the proximal chamber, wherein the second substance is disposed in the proximal chamber;inserting an elongate member at least partially into the body interior, the elongate member having a plurality of ...

System and method for safety syringe

A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body.

System and method for safety syringe

A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior.

INJECTION SYSTEM AND METHOD

An injection system includes an injection system body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the injection system body, forming a proximal drug and a distal drug chamber. The system further includes a plunger member configured to insert the proximal stopper member relative to the injection system body. Moreover, the system includes a valve forming an openable barrier between the distal needle interface and the distal drug chamber. The valve includes an outer member including a distal diaphragm, and an inner member. The distal diaphragm is configured to elastically deform distally away from the inner member with increased pressure in the distal drug chamber to allow flow from the distal drug chamber to the distal needle interface.

SYSTEM AND METHOD FOR SAFETY SYRINGE

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber. 1. A system for injecting , comprising:a. a syringe body defining an interior medicine chamber and a distal needle interface;b. a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber;c. a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; andd. a needle having proximal and distal ends, the proximal end being removably coupled to the distal needle interface of the syringe body and at least partially retractable into the interior medicine chamber upon manipulation of the plunger member relative to the syringe body to transform a plunger latching member from a latched state to an unlatched state, the plunger latching member intercoupled between the syringe body and the plunger member;wherein the plunger latching member is substantially disposed within a lumen defined by the plunger member.2. The system of claim 1 , wherein the syringe body comprises an off-the-shelf syringe body.3. The system of claim 1 , wherein the syringe body comprises a generally cylindrical geometry.4. The system of claim 1 , wherein the medicine chamber is configured to contain between about 0.5 cc and about 5 cc of medicine.5. The system of claim 4 , wherein the medicine ...

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1a. a delivery member having proximal and distal ends;b. a first helical member having proximal and distal ends and a helical shape, the proximal end coupled to the delivery member distal end, the distal end extending distally of the delivery member distal end;c. an anchor member removably coupled to the helical member distal end; andd. a suture member coupled distally to a portion of the anchor member and extending proximally to a position wherein at least a portion of it may be freely manipulated by an operator;wherein upon rotation of the delivery member in a first direction, the first helical member and coupled anchor member are advanced across at least a portion of the wall of the tissue structure, pulling along the distal portion of the suture member in a deployed suture pattern which remains coupled to the anchor member, the deployed suture pattern being characterized in that it is substantially helical and represents a number of helical loops encapsulated by the wall of the tissue structure that is greater than about one and one-half helical loops, and is less than about four helical loops.. A system for providing surgical access across a wall of a tissue structure, comprising: This application is a continuation of U.S. patent application Ser. No. 13/725,903 filed on Dec. 21, 2012, which is a continuation of U.S. patent application Ser. No. 13/640,041 filed on Oct. 8, 2012 which is a U.S. National Stage filing under 35 U.S.C. §371 of International Application No. PCT/US2011/040085, ...

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member. 1. A system for injecting , comprising:a syringe body defining a proximal opening and a distal needle interface; a needle retention feature disposed in the plunger interior,', 'an energy-storage member disposed in the plunger interior, and', 'an energy-storage member latching member disposed in the plunger interior; and, 'a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body, the plunger member including'} a needle having a needle proximal end feature,', 'a hub, and', 'a needle latching member configured to couple the needle to the hub,, 'a needle hub assembly coupled to the distal needle interface of the syringe body, the needle assembly including'}wherein the needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body to transform the energy-storage member latching member from a latched state to an unlatched state, andwherein the energy-storage member latching member is intercoupled between an interior surface of ...

System and method for transapical access and closure

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1 'wherein the externally projecting seal member defines an outer seal margin defining an outer seal diameter;', 'a. a base member having a proximal end and a distal end and an externally projecting seal member disposed therebetween and configured to interface with at least a portion of the tissue wall to assist in sealing the defect, the proximal end being configured to be manually manipulated by an operator;'} 'wherein in the collapsed configuration, each of the bendable strut members project out from a coupling junction with the distal portion of the base member, sweep toward the proximal end of the base member, and bend toward the outer seal margin;', 'b. a first plurality of bendable strut members coupled to the distal end of the base member and configured to occupy a collapsed configuration when bent in place toward the base member, and an expanded configuration when unrestrained;'}c. a proximal hub member movably and coaxially coupled about the outside of the base member and advanceable along a length of the base member; and 'wherein in the collapsed configuration, each of the bendable strut members project out from a coupling junction with the proximal hub member and sweep toward the distal end of the base member.', 'd. a second plurality of bendable strut members coupled to the proximal hub member and configured to occupy a collapsed configuration when bent in place toward the base member, and an expanded configuration when unrestrained;'}. An apparatus for closing a defect in a ...

Implantable medical device with openings for delivery of beneficial agents with combination release kinetics

A method and system for delivering drug includes a first set of holes filled with a first formulation of the drug and a second set of holes filled with a second formulation of the same drug. This dual formulation or dual release kinetic system allows the creation of specifically tailored release kinetics by summation of multiple release kinetics.

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body. 1. A system for mixing drug products and injecting , comprising:a cylindrical injection body defining a proximal opening and a distal needle interface at a distal end thereof;proximal and distal stopper members disposed in the cylindrical injection body, forming a proximal drug chamber between the proximal and distal stopper members and a distal drug chamber between the distal stopper member and the distal end of the cylindrical injection body; a needle retention feature disposed in the plunger interior,', 'an energy-storage member disposed in the plunger interior, and', 'an energy-storage member latching member disposed in the plunger interior; and, 'a plunger member defining a plunger interior and configured to insert the proximal stopper member relative to the cylindrical injection body, the plunger member including'} a needle having a needle proximal end feature,', 'a hub, and', 'a needle latching member configured to couple the needle to the hub,, 'a needle hub assembly coupled to the distal needle interface of the cylindrical injection body, the needle hub ...

System and method for transapical access and closure

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1a. a delivery member having proximal and distal ends;b. a plurality of helical members, each having proximal and distal ends and a helical shape, each proximal end coupled to the delivery member distal end, each distal end extending distally of the delivery member distal end;c. a plurality of anchor members removably coupled to the helical member distal ends; andd. a plurality of suture members coupled distally to a portion of one of the anchor members and extending proximally to a position wherein at least a portion of each may be freely manipulated by an operator;wherein upon rotation of the delivery member in a first direction, the helical members and coupled anchor members are advanced across at least a portion of the wall of the tissue structure, pulling along the distal portions of the suture members in a deployed suture pattern which remains coupled to the anchor member.. A system for providing surgical access across a wall of a tissue structure, comprising: This application is a continuation of U.S. patent application Ser. No. 13/725,897 filed on Dec. 21, 2012, which is a continuation of U.S. patent application Ser. No. 13/640,041 filed on Oct. 8, 2012 and issued as U.S. Pat. No. 9,044,267 on Jun. 2, 2015, which is a U.S. National Stage filing under 35 U.S.C. §371 of International Application No. PCT/US2011/040085, filed Jun. 10, 2011, which claims priority to U.S. Provisional Application Nos. 61/354,177, filed Jun. 11, 2010 and 61/361,365 filed Jul. 2, 2010. Priority to the ...

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1a. a delivery member having proximal and distal ends;b. a first helical member having proximal and distal ends and a helical shape, the proximal end coupled to the delivery member distal end, the distal end extending distally from the delivery member distal end;c. an anchor member removably coupled to the helical member distal end;d. a suture member coupled distally to a portion of the anchor member and extending proximally to a position wherein at least a portion of it may be freely manipulated by an operator; ande. an elongate instrument at least partially inserted through the first helical member;wherein upon rotation of the delivery member in a first direction, the first helical member and coupled anchor member are advanced across at least a portion of the wall of the tissue structure, pulling along the distal portion of the suture member in a deployed suture pattern which remains coupled to the anchor member, the deployed suture pattern being characterized in that it represents a number of helical loops encapsulated by the wall of the tissue structure that is greater than about one and one-half helical loops, and is deployed in a substantially helical configuration selected to movably accommodate the elongate instrument therethrough.. A system for providing surgical access across a wall of a tissue structure, comprising: This application is a continuation of U.S. patent application Ser. No. 14/558,584 filed on Dec. 2, 2014, which is a continuation of U.S. patent application Ser. No. ...

System and method for safety syringe

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

Injection system and method

An injection system includes a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the syringe body, forming respective proximal and distal drug chambers. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the syringe body. Moreover, the system includes a fluid conveying assembly including a penetrating member configured to penetrate the distal stopper member to fluidly couple the proximal and distal drug chambers, a distal exit tube, and a transfer member disposed at least partially around a portion of the penetrating member and defining a fluid passage. A distal end of the penetrating member is disposed in the distal exit tube.

System and method for safety syringe

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

System and method for safety syringe

A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior.

System and method for safety syringe

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

SYSTEM AND METHOD FOR SAFETY SYRINGE

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body.

SYSTEM AND METHOD FOR SAFETY SYRINGE

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber. 190-. (canceled)91. A system for mixing drug products and injecting , comprising:a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface and a distal medicine port at a distal end thereof;proximal and distal stopper members disposed in the syringe body, forming a proximal drug chamber between the proximal and distal stopper members and a distal drug chamber between the distal stopper member and the distal end of the syringe body; a needle retention feature disposed in the plunger interior,', 'an energy storage member disposed in the plunger interior, and', 'an energy storage member latching member disposed in the plunger interior; and, 'a plunger member defining a plunger interior and configured to be manually manipulated to insert the proximal stopper member relative to the syringe body, the plunger member including'} a needle having a needle proximal end,', 'a hub, and', 'a needle latching member configured to couple the needle to the hub,, 'a needle hub assembly coupled to the distal needle interface of the syringe body, the needle assembly including'}wherein first and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. ...

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1. An apparatus for closing a defect in a tissue wall , comprising: 'wherein the seal member defines an outer seal margin defining an outer seal diameter;', 'a. a base member having a proximal end and a distal end and a seal member disposed therebetween, the proximal end being configured to be manually manipulated by an operator;'} 'wherein in the collapsed configuration, each of the bendable strut members project out from a coupling junction with the distal portion of the base member, sweep toward the proximal end of the base member, and bend toward the outer seal margin;', 'b. a first plurality of bendable strut members coupled to the distal end of the base member and configured to occupy a collapsed configuration when bent in place toward the base member, and an expanded configuration when unrestrained;'}c. a proximal hub member movably coupled to the base member and advanceable along a length of the base member; and 'wherein in the collapsed configuration, each of the bendable strut members project out from a coupling junction with the proximal hub member and sweep toward the distal end of the base member.', 'd. a second plurality of bendable strut members coupled to the proximal hub member and configured to occupy a collapsed configuration when bent in place toward the base member, and an expanded configuration when unrestrained;'}2. The apparatus of claim 1 , further comprising a tubular delivery member defining a delivery lumen through which the base member claim 1 , first plurality ...

SYSTEM AND METHOD FOR SAFETY SYRINGE

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.

System and method for transapical access and closure

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

System and method for safety syringe

A system for mixing drug products and injecting includes a syringe body, proximal and distal stopper members disposed in the syringe body, a plunger member, and a needle hub assembly coupled to the distal needle interface of the syringe body. The proximal and distal stopper members form a proximal drug chamber between there between and a distal drug chamber between the distal stopper member and a distal end of the syringe body. The plunger member includes a needle retention feature, an energy-storage member, and an energy-storage member latching member all disposed in disposed in a plunger interior. First and second sizes of the respective proximal and distal drug chambers can be modified by movement of the proximal and distal stopper members relative to the syringe body. The needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body.

INJECTION SYSTEM AND METHOD

An injection system includes a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the syringe body, forming respective proximal and distal drug chambers. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the syringe body. Moreover, the system includes a fluid conveying assembly including a penetrating member configured to penetrate the distal stopper member to fluidly couple the proximal and distal drug chambers, a distal exit tube, and a transfer member disposed at least partially around a portion of the penetrating member and defining a fluid passage. A distal end of the penetrating member is disposed in the distal exit tube.

SYSTEM AND METHOD FOR SAFETY SYRINGE

A system for injecting includes a syringe body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the syringe body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member. 1. A system for injecting , comprising:a syringe body defining a proximal opening and a distal needle interface; a needle retention feature disposed in the plunger interior,', 'an energy-storage member disposed in the plunger interior, and', 'an energy-storage member latching member disposed in the plunger interior; and, 'a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the syringe body, the plunger member including'} a needle having a needle proximal end feature,', 'a hub, and', 'a needle latching member configured to couple the needle to the hub,, 'a needle hub assembly coupled to the distal needle interface of the syringe body, the needle assembly including'}wherein the needle is at least partially retractable into plunger interior upon manipulation of the plunger member relative to the syringe body to transform the energy-storage member latching member from a latched state to an unlatched state,wherein the energy-storage member latching member is intercoupled between an interior surface of the ...

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1. A system for providing surgical access across a wall of a tissue structure , comprising:a. a delivery member having proximal and distal ends;b. a first helical member having proximal and distal ends and a helical shape, the proximal end coupled to the delivery member distal end, the distal end extending distally from the delivery member distal end;c. an anchor member removably coupled to the helical member distal end;d. a suture member coupled distally to a portion of the anchor member and extending proximally to a position wherein at least a portion of it may be freely manipulated by an operator; ande. an elongate instrument at least partially inserted through the first helical member;wherein upon rotation of the delivery member in a first direction, the first helical member and coupled anchor member are advanced across at least a portion of the wall of the tissue structure, pulling along the distal portion of the suture member in a deployed suture pattern which remains coupled to the anchor member, the deployed suture pattern being characterized in that it represents a number of helical loops encapsulated by the wall of the tissue structure that is greater than about one and one-half helical loops, and is deployed in a substantially helical configuration selected to movably accommodate the elongate instrument therethrough.2. The system of claim 1 , wherein upon rotation of the delivery member in a second direction opposite to the first direction claim 1 , a reverse load is applied to ...

System and method for transapical access and closure

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1. A system for providing surgical access across a wall of a tissue structure , comprising:a. a delivery member having proximal and distal ends;b. a first helical member having proximal and distal ends and a helical shape, the proximal end coupled to the delivery member distal end, the distal end extending distally of the delivery member distal end;c. an anchor member removably coupled to the helical member distal end; andd. a suture member coupled distally to a portion of the anchor member and extending proximally to a position wherein at least a portion of it may be freely manipulated by an operator;wherein upon rotation of the delivery member in a first direction, the first helical member and coupled anchor member are advanced across at least a portion of the wall of the tissue structure, pulling along the distal portion of the suture member in a deployed suture pattern which remains coupled to the anchor member, the deployed suture pattern being characterized in that it represents a number of helical loops encapsulated by the wall of the tissue structure that is greater than about one and one-half helical loops, and is deployed in a substantially helical configuration selected to provide circumferential slack to facilitate relative movement of an elongate instrument therethrough.2. The system of claim 1 , wherein upon rotation of the delivery member in a second direction opposite to the first direction claim 1 , a reverse load is applied to the delivery member and coupled first helical ...

SYSTEM AND METHOD FOR TRANSAPICAL ACCESS AND CLOSURE

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed. 1a. a base member having a proximal end and a distal end and an externally projecting seal member disposed therebetween and configured to interface with at least a portion of the tissue wall to assist in sealing the defect, the proximal end being configured to be manually manipulated by an operator;wherein the externally projecting seal member defines an outer seal margin defining an outer seal diameter; 'wherein in the collapsed configuration, each of the bendable strut members project out from a coupling junction with the distal portion of the base member, sweep toward the proximal end of the base member, and bend toward the outer seal margin;', 'b. a first plurality of bendable strut members coupled to the distal end of the base member and configured to occupy a collapsed configuration when bent in place toward the base member, and an expanded configuration when unrestrained;'}c. a proximal hub member movably and coaxially coupled about the outside of the base member and advanceable along a length of the base member; and 'wherein in the collapsed configuration, each of the bendable strut members project out from a coupling junction with the proximal hub member and sweep toward the distal end of the base member.', 'd. a second plurality of bendable strut members coupled to the proximal hub member and configured to occupy a collapsed configuration when bent in place toward the base member, and an expanded configuration when unrestrained;'}. An apparatus for closing a defect in a tissue ...

Injection system and method

An injection system includes a syringe body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the syringe body, forming respective proximal and distal drug chambers. The system further includes a plunger member configured to be manually manipulated to insert the proximal stopper member relative to the syringe body. Moreover, the system includes a fluid conveying assembly including a penetrating member configured to penetrate the distal stopper member to fluidly couple the proximal and distal drug chambers, a distal exit tube, and a transfer member disposed at least partially around a portion of the penetrating member and defining a fluid passage. A distal end of the penetrating member is disposed in the distal exit tube.

Reservoir eluting stent

An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a first diameter to a second diameter. A plurality of different beneficial agents may be loaded into different openings within the struts for delivery to:the tissue. For treatment of conditions such as restenosis, different agents are loaded into different openings in the device to address different biological processes involved in restenosis and are delivered at different release kinetics matched to the biological process treated. The different agents may also be used to address different diseases from the same drug delivery device. In addition, anti-thrombotic agents may be affixed to at least a portion of the surfaces of the medical device for the prevention of sub-acute thrombosis. To ensure that the different agents remain affixed to the device as well as to each other, primer layers may be utilized.

System and method for transapical access and closure

Embodiments are described for creating and closing tissue access ports, such as transapical access ports, which involve placement of an introducer across the subject tissue structure, and deployment of a controllable port closure device assembly configured to remain in place with a ratcheting mechanism, and to hold the tissue surrounding the previous access port location closed against a sealing disc with proximal and distal strut assemblies, after the introducer has been removed.

Rapamycin reservoir eluting stent

System and method for safety syringe

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

System and method for safety syringe

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method includes introducing a first substance into a distal end of the body interior. The method includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. The method includes introducing a second substance into the body interior. The method includes disposing a proximal stopper member in the body interior. The method includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method includes coupling a plunger member to the proximal stopper member.

Implantable medical device with openings for delivery of beneficial agents with combination release kinetics

A method and system for delivering drug includes a first set of holes filled with a first formulation of the drug and a second set of holes filled with a second formulation of the same drug. This dual formulation or dual release kinetic system allows the creation of specifically tailored release kinetics by summation of multiple release kinetics.

Lobed balloon catheter and method of use

A balloon catheter with a balloon having at least a section which has an uninflated configuration with at least two lobes and an inflated configuration with a cylindrical surface. In a presently preferred embodiment, the balloon has a lobed inner surface and a lobed outer surface. In one embodiment, the balloon has a uniform wall thickness around a circumference of the lobed balloon section. However, in alternative embodiments the balloon wall thickness may nonuniform around the balloon circumference. Each lobe forms a deflated balloon wing when the balloon is deflated.

Reservoir Eluting Stent

Injection system and method

An injection system includes an injection system body defining a proximal opening at a proximal end thereof and a distal needle interface at a distal end thereof. The system also includes proximal and distal stopper members disposed in the injection system body, forming a proximal drug and a distal drug chamber. The system further includes a plunger member configured to insert the proximal stopper member relative to the injection system body. Moreover, the system includes a valve forming an openable barrier between the distal needle interface and the distal drug chamber. The valve includes an outer member including a distal diaphragm, and an inner member. The distal diaphragm is configured to elastically deform distally away from the inner member with increased pressure in the distal drug chamber to allow flow from the distal drug chamber to the distal needle interface.

System and method for safety syringe

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber =to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to= insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at =least partially inserted into the stopper =member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at= least partially contained within the interior medicine chamber.

System and method for safety syringe

One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; and a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially inserted into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber.

安全注射器用のシステムおよび方法

【課題】医薬品を混合し注射するシステムを提供する。 【解決手段】注射器本体３４と、注射器本体内に配置された近位および遠位ストッパ部材３２、３６と、プランジャ部材と、注射器本体の遠位ニードルインタフェースに結合されたニードルハブアセンブリを具えるシステム。近位および遠位ストッパ部材は、それらの間および遠位ストッパ部材と注射器本体の遠位端との間の遠位薬剤チャンバ４２との間に近位薬剤チャンバ４０を形成する。プランジャ部材は、ニードル保持構造と、エネルギー貯蔵部材と、エネルギー貯蔵部材ラッチ部材とを具え、これらはすべてプランジャ内部に配置されている。近位および遠位薬剤チャンバのそれぞれの第１および第２のサイズは、注射器本体に対する近位および遠位ストッパ部材の移動によって変えることができる。 【選択図】図６－１

System and method for safety syringe

A system for serially injecting liquids includes a syringe body, proximal and distal stopper members disposed in the syringe body, a first liquid in a distal chamber, a second liquid in a proximal chamber, a plunger member, and a needle hub assembly coupled to a distal needle interface of the syringe body. The plunger member includes a needle retention feature disposed in a plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. Manipulating the plunger member to insert the proximal stopper member distally relative to the syringe body initially expels the first liquid, then the second liquid. The needle is at least partially retractable into plunger interior.

安全注射器のためのシステム及び方法

【課題】安全注射器のための好適なシステム及び方法を提供すること。【解決手段】１つの実施形態は、注射のためのシステムを対象とし、本システムは、内部薬剤チャンバを画定する注射器本体；薬剤を薬剤チャンバ内に収容するために内部薬剤チャンバに挿入されるように構成されているストッパー部材；ストッパー部材を注射器本体に対して挿入するために手動で操作されるように構成されているプランジャ部材；ならびに近位端及び遠位端を有する針であって、近位端が、ストッパー部材中に少なくとも部分的に挿入されることで、ストッパー部材の格納の際に、針をストッパーと共に近位に引っ張って、内部薬剤チャンバ内に少なくとも部分的に収容するように構成されているアンカー幾何形状を備える、針、を備える。【選択図】図１Ｂ

System and method for safety syringe

A method for preparing a pre-filled multi-chamber injection system includes providing an injection system body, the injection system body defining an open proximal end, a body interior, and an open distal end. The method also includes introducing a first substance into a distal end of the body interior. The method further includes disposing a distal stopper member in the body interior, the distal stopper member and the injection system body defining proximal and distal chambers in the body interior. Moreover, the method includes introducing a second substance into the body interior. In addition, the method includes disposing a proximal stopper member in the body interior. The method also includes inserting an elongate member at least partially into the body interior, the elongate member having a plurality of flow channels for fluidly coupling the proximal and distal chambers. The method further includes coupling a plunger member to the proximal stopper member.

System for safety syringe