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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 2865. Отображено 100.
12-01-2012 дата публикации

Energy based devices and methods for treatment of patent foramen ovale

Номер: US20120010608A1
Автор: Dan Francis, Hanson S. Gifford, Iii, Jose Alejandro, Kenneth Horne, Mark E. Deem, William Malecki
Принадлежит: Terumo Corp

Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device fuirther include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

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Номер записи: 1
02-02-2012 дата публикации

Sequential Activation RF Electrode Set for Renal Nerve Ablation

Номер: US20120029500A1
Автор: Mark L. Jenson
Принадлежит: Boston Scientific Scimed Inc

A catheter includes a flexible shaft having a length sufficient to access a patient's renal artery. A treatment element at the distal end of the shaft is dimensioned for deployment within the renal artery. The treatment element comprises a radially expandable structure configured to maintain positioning within the renal artery. A multiplicity of electrodes are spaced apart on the treatment element and configured for switchable activation and deactivation in a predetermined sequence to generate overlapping zones of heating directed at perivascular nerves of the renal artery. The overlapping heating zones comprise a distal zone associated with relatively high current densities at a distance from the treatment element sufficient to ablate the perivascular renal nerves and a proximal zone associated with current densities lower than those of the distal zone and insufficient to cause thermal injury to tissue of the renal artery adjacent the treatment element.

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Номер записи: 2
03-05-2012 дата публикации

Catheter with coronary sinus ostium anchor

Номер: US20120108953A1
Автор: Amy E. Thompson-Nauman, H. Toby Markowitz
Принадлежит: MEDTRONIC ABLATION FRONTIERS LLC

A method of treating cardiac tissue is provided, including positioning a first chamber of a medical device adjacent an atrial wall; directing a cryogenic coolant into the first chamber; anchoring the first chamber to the atrial wall through cryoadhesion; directing a distal portion of the medical device into the coronary sinus; and positioning a cardiac lead through at least a portion of the coronary sinus with the distal portion. The method may include measuring a temperature of the first chamber; removing the first chamber from the atrial wall once a predetermined threshold temperature of the first chamber is reached; anchoring a second chamber of the medical device to a portion of the coronary sinus; and/or perfusing blood flow through at least a portion of the second chamber.

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Номер записи: 3
10-05-2012 дата публикации

In-plane dual loop fixed diameter electrophysiology catheters and methods of manufacturing therefor

Номер: US20120116199A1
Автор: Alan de la Rama, Jennifer Velasco, Kailing Chen
Принадлежит: de la Rama Alan, Jennifer Velasco, Kailing Chen

An EP catheter includes a tubular body having a proximal region, a neck region, and a distal portion predisposed into an in-plane dual loop (at least, approximately, more or less) configuration and including a plurality of diagnostic electrodes. In deflectable catheter forms, at least one activation wire extends through at least a portion of the proximal region of the catheter body and is adapted to deflect the distal portion up to approximately 180 degrees relative to the proximal region. The catheter can be operated manually by a clinician or via a clinician-surrogate such as a computer processor-controlled surgical system. In addition, a variety of localization, visualization, and/or orientation-specific elements can be incorporated into the devices described, depicted, and claimed herein (e.g., metallic coil members, active impedance emitting or receiving electrodes, fluoroscopically opaque materials, and the like).

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Номер записи: 4
10-05-2012 дата публикации

Fixed loop deflectable electrophysiology catheters having an extended braid primary shaft coupled to the periphery of the fixed loop and methods of manufacturing therefor

Номер: US20120116200A1
Автор: Alan de la Rama, Jennifer Velasco, Pianka Roy
Принадлежит: de la Rama Alan, Jennifer Velasco, Pianka Roy

An EP catheter includes a tubular body having a proximal region, a neck region, and a distal portion predisposed into a single shallow helical fixed-diameter loop configuration and including a plurality of diagnostic electrodes. In deflectable catheter forms, at least one activation wire extends through at least a portion of the proximal region of the catheter body and is adapted to deflect the up to approximately 180 degrees relative to the proximal region. The catheter can be operated manually by a clinician or via a clinician-surrogate such as a computer processor-controlled surgical system. In addition, a variety of localization, visualization, and/or orientation-specific elements can be incorporated into the devices described, depicted, and claimed herein (e.g., metallic coil members, active impedance emitting or receiving electrodes, fluoroscopically opaque materials, and the like).

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Номер записи: 5
17-05-2012 дата публикации

Balloon catheter system

Номер: US20120123331A1
Автор: Shutaro Satake
Принадлежит: Japan Electel Inc

A balloon catheter system enables only a target site to be efficiently ablated, ensuring a balloon to be able to be brought into close contact with the target site in conformity to a shape of the target site. The balloon includes a contact portion that contacts the target site and a noncontact portion that does not contact the target site. A membrane thickness of the contact portion is thinner than that of the noncontact portion The target site that is in contact with the thin contact portion is selectively ablated, while the thick noncontact portion is less likely to exhibit a temperature increase. Hence, only the target portion is efficiently ablated.

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Номер записи: 6
21-06-2012 дата публикации

Tuned rf energy for selective treatment of atheroma and other target tissues and/or structures

Номер: US20120157988A1
Автор: Arthur G. Blanck, Corbett W. Stone, Michael F. Hoey, Raphael M. Michel, Tom A. Steinke
Принадлежит: Vessix Vascular Inc

A catheter and catheter system can use energy tailored for remodeling and/or removal of target material along a body lumen, often of atherosclerotic material of a blood vessel of a patient. An elongate flexible catheter body with a radially expandable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector system may measure and/or characterize the atherosclerotic material and its location, optionally using impedance monitoring.

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Номер записи: 7
09-08-2012 дата публикации

Systems, assemblies, and methods for treating a bronchial tree

Номер: US20120203216A1
Автор: Martin L. Mayse, Steven C. Dimmer
Принадлежит: Innovative Pulmonary Solutions Inc

Systems, assemblies, and methods to treat pulmonary diseases are used to decrease nervous system input to distal regions of the bronchial tree within the lungs. Treatment systems damage nerve tissue to temporarily or permanently decrease nervous system input. The treatment systems are capable of heating nerve tissue, cooling the nerve tissue, delivering a flowable substance that cause trauma to the nerve tissue, puncturing the nerve tissue, tearing the nerve tissue, cutting the nerve tissue, applying pressure to the nerve tissue, applying ultrasound to the nerve tissue, applying ionizing radiation to the nerve tissue, disrupting cell membranes of nerve tissue with electrical energy, or delivering long acting nerve blocking chemicals to the nerve tissue.

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Номер записи: 8
30-08-2012 дата публикации

Devices and methods for treatment of luminal tissue

Номер: US20120220996A1
Автор: Carson J. Shellengberger, George H. Smith, Jennifer A. Hodor, Jerome Jackson, Roger A. Stern, Roy D. Corbitt, Vincent N. Sullivan
Принадлежит: TYCO HEALTHCARE GROUP LP

Devices and methods are provided for treatment of tissue in a body lumen with an electrode deployment device. Embodiments typically include a device with a plurality of electrodes having a pre-selected electrode density arranged on the surface of a support. The support may comprise a non-distensible electrode backing that is spirally furled about an axis and coupled to an expansion member such as an inflatable elastic balloon. In some embodiments, the balloon is inflated to selectively expose a portion of the electrode surface while maintaining the electrode density.

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Номер записи: 9
27-09-2012 дата публикации

Cooling systems for electrode arrays

Номер: US20120245577A1
Автор: Alexander J. Asconeguy, Ricardo D. Roman, Teresa Ann Mihalik, Timothy J. Corvi
Принадлежит: MEDTRONIC ABLATION FRONTIERS LLC

A medical device is disclosed, including a catheter body; an electrode array coupled to the catheter body, the electrode array being transitionable from a substantially linear configuration to a substantially helical configuration; and a fluid conduit coupled to the catheter body spaced apart from the electrode array, wherein the fluid conduit is transitionable from a substantially linear configuration to a substantially helical configuration. The device may include a fluid source in communication with the fluid conduit and a radiofrequency signal generator coupled to the electrode array.

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Номер записи: 10
01-11-2012 дата публикации

Balloon Resection Method

Номер: US20120277578A1
Автор: Erhan H. Gunday, Lawrence J. Gerrans
Принадлежит: Sanovas Inc

A balloon resection method is disclosed generally comprising inserting a catheter with at least one balloon having an outer wall with a resecting, non-slip surface for resecting unwanted biological material, such as tissues or tumors, and supplying fluid thereto in pulsed fashion to repeatedly deflate and inflate the balloon. In certain embodiments, a pump controls the pulsed supply of fluid based on an established frequency or change in volume. In some embodiments, the a keyed connector is used to identify the balloon type, and in some cases, intra-lumen diameters and densities are calculated. In some embodiments, the balloon portion of the catheter includes multiple balloon segments, which in some cases, are inflatable separately from one another.

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Номер записи: 11
22-11-2012 дата публикации

Energy facilitated composition delivery

Номер: US20120296262A1
Автор: Osamu Katoh, Wayne Ogata
Принадлежит: RetroVascular Inc

A device for delivering a composition to a hollow body region is disclosed. In one aspect, the device comprises a first longitudinal member and a second longitudinal member. Both of the longitudinal members may comprise conductive electrodes. The longitudinal members are further configured to be connected to an energy source such that the conductive electrodes are configured to generate an energy field. At least one of the longitudinal members further comprises a delivery element configured to deliver at least one composition to the body region, such that the composition is delivered in a direction that is influenced by the generated energy field. In one aspect, the body region is a vessel comprising an occlusion.

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Номер записи: 12
07-02-2013 дата публикации

System and method for mapping gastro-intestinal electrical activity

Номер: US20130035576A1
Автор: Andrew John Pullan, Gregory Brian O'grady, Jonathan Christopher Erickson, Leo Koon-Wah Cheng, Peng Du
Принадлежит: Auckland Uniservices Ltd

A gastro-electrical activity mapping system and comprises a catheter insertable through a natural orifice into the gastro-intestinal (GI) tract and comprising an array of electrodes for contacting an interior surface of a section of the GI tract to detect electrical potentials at multiple electrodes, and a signal analysis and mapping system arranged to receive and process electrical signals from multiple electrodes of the array and spatially map GI smooth muscle electrical activity as an activation time map, a velocity map, or an amplitude map, which may be in the form of contour plots and may be mapped on an anatomical computer model of at least the section of the GI tract and may be animated. A GI mapping method and catheter are also claimed.

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Номер записи: 13
14-02-2013 дата публикации

Surgical Snare with Electrosurgical Tip and Method of Use

Номер: US20130041372A1
Автор: Robert E. Welt, Thomas B. Miller, William L. Athas
Принадлежит: Transenterix Inc

A medical device includes a tissue dissector and a snare loop on a common shaft. At least the distal tip of the snare loop is energizable to function as an electrosurgical element for tissue dissection. In use the snare loop is partially extended from the shaft to expose the electrosurgical element for electrosurgical dissection, and the snare loop is fully extended from the shaft to deploy the snare loop for retrieval and positioning of an implant such as a gastric banding device. The snare loop may be deployed through a pair of jaws also mounted on the shaft for use in tissue dissection.

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Номер записи: 14
25-07-2013 дата публикации

Devices for thermally-induced hepatic neuromodulation

Номер: US20130190748A1
Автор: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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Номер записи: 15
01-08-2013 дата публикации

Selective accumulation of energy with or without knowledge of tissue topography

Номер: US20130197614A1
Автор: Arthur G. Blanck, Linas Kunstmanas, Rolfe Tyson Gustus
Принадлежит: Vessix Vascular Inc

Medical devices and methods for making and using medical devices are disclosed. An example method may include a method for heating a body tissue region adjacent to a body lumen. The method may include positioning an energy delivery portion of a catheter within the lumen and engaging the body lumen with the energy delivery portion. Engaging the body lumen may complete a plurality of circuits. The method may also include determining a pulse characteristic in response to a thermal property of a first tissue type and applying controlled pulsed electrical energy with the pulse characteristic from the energy delivery portion through the plurality of circuits.

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Номер записи: 16
19-09-2013 дата публикации

Expandable electrode device and methods for nerve modulation

Номер: US20130245622A1
Автор: Huisun Wang, James M. Anderson
Принадлежит: Boston Scientific Scimed Inc

Embodiments of the disclosure provide an ablative system for nerve modulation through wall of a blood vessel. The ablative catheter system includes an elongate member having a proximal end and a distal end, a number of electrode elements, an expansion mechanism. The electrode elements are finger-like structures mounted at their proximal ends for pivotal rotation radially outward from the longitudinal axis of the elongate member from a collapsed state. Each electrode element having inner and an outer surface with an electrode portion connected to a source of electrical energy and an insulated portion and a slope surface forming the proximal portion of the inner surface, sloping outward from the longitudinal axis of the elongate member, and a tip portion at the distal portion of the inner surface, angled toward the longitudinal axis of the elongate member. The electrode element inner surfaces in the collapsed state define a central cavity.

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Номер записи: 17
07-11-2013 дата публикации

Delivery devices with coolable energy emitting assemblies

Номер: US20130296647A1
Автор: Martin L. Mayse, Steven C. Dimmer
Принадлежит: Holaira Inc

Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input.

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Номер записи: 18
20-02-2014 дата публикации

Modulation of nerves that innervate the liver

Номер: US20140052121A1
Автор: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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Номер записи: 19
06-03-2014 дата публикации

Neuromodulation methods using balloon catheter

Номер: US20140066924A1
Автор: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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Номер записи: 20
20-03-2014 дата публикации

Methods and apparatus for renal neuromodulation

Номер: US20140081259A1
Автор: Denise Zarins, Douglas Sutton, Erik Thai, Hanson Gifford, III, Howard R. Levin, Mark E. Deem, Mark Gelfand
Принадлежит: Medtronic Ardian Luxembourg SARL

Methods and apparatus are provided for renal neuromodulation using a pulsed electric field to effectuate electroporation or electrofusion. It is expected that renal neuromodulation (e.g., denervation) may, among other things, reduce expansion of an acute myocardial infarction, reduce or prevent the onset of morphological changes that are affiliated with congestive heart failure, and/or be efficacious in the treatment of end stage renal disease. Embodiments of the present invention are configured for percutaneous intravascular delivery of pulsed electric fields to achieve such neuromodulation.

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Номер записи: 21
07-01-2021 дата публикации

Medical device for use in bodily lumens, for example an atrium

Номер: US20210000537A1
Автор: Daniel Gelbart, Douglas Wayne GOERTZEN, Fernando Luis De Souza Lopes
Принадлежит: Kardium Inc

A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s).

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Номер записи: 22
02-01-2020 дата публикации

SYSTEM FOR INDUCING DESIRABLE TEMPERATURE EFFECTS ON BODY TISSUE

Номер: US20200000519A1
Автор: Blanck Arthur G., Briggs Len, Gustus Rolfe Tyson, Hoey Michael F., Perry Mike, Stone Corbett W.
Принадлежит:

A catheter and catheter system may be used to treat disease tissue by gentle heating in combination with gentle or standard dilation. An elongate flexible catheter body with a radially expandable balloon having a plurality of electrodes engage tissue including diseased tissue when the structure expands. 1. A system , comprising:a catheter body having a proximal end and a distal end with an axis therebetween;a radially expandable member having a low profile insertion configuration and a larger profile configuration; anda plurality of electrode pairs included on a plurality of flexible circuits, the flexible circuits distributed about an outer surface of the expandable member, so as to define a plurality of remodeling zones extending circumferentially about a wall of a body lumen when the expandable member is in the larger profile configuration; andwherein the plurality of electrode pairs is configured to transmit a tissue remodeling energy to each of the plurality of remodeling zones such that the tissue remodeling energy transmitted to remodeling zones including both a target tissue and a collateral tissue heats the target tissue sufficiently to efficaciously alter the target tissue without causing thermal damage to the collateral tissue.2. The system of claim 1 , wherein each of the flexible circuits includes an associated bipolar electrode pair.3. The system of claim 2 , wherein the electrodes of each bipolar electrode pair are disposed on its associated flexible circuit so as to have a predetermined bipolar pair separation distance therebetween when the expandable member is in the larger profile configuration.4. The system of claim 2 , wherein the bipolar electrode pairs are configured to be energized with RF energy claim 2 , and wherein the electrodes of the electrode pairs are circumferentially separated.5. The system of claim 4 , wherein a circumferential distance between the electrodes of the electrode pairs is within a range from about 0.25 to 2.5 mm.6. The ...

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Номер записи: 23
04-01-2018 дата публикации

An improved catheter and method of manufacture thereof

Номер: US20180000540A1
Автор: David Ogle, Roman GREIFENEDER
Принадлежит: CATHRX LTD

A sheath adapted for use with a catheter is disclosed comprising an electrical lead having a proximal end and a distal end and a lumen extending from the proximal end to the distal end, the electrical lead including a tubular member of non-conductive material. At least a first set of electrical conductors and a second set of electrical conductors extend from the proximal end to the distal end laid on the non-conductive tubular member, and an outer layer of non-conductive material is applied over the electrical conductors to cover the conductors. One or more electrodes are disposed on a distal portion of the sheath. Each electrode is in electrical communication with at least one of the electrical conductors through the outer layer. The first set of electrical conductors is helically wrapped around the lumen and the second set of electrical conductors is helically wrapped around the first set of electrical conductors.

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Номер записи: 24
04-01-2018 дата публикации

FLEXIBLE ELECTRODE

Номер: US20180000542A1
Автор: Marass Tim, Marrs James C., Oliverius Andrew Ryan
Принадлежит:

A flexible electrode includes an internal spring with an increased spring rate and/or distal-end and proximal-end turns having increased diameters. In an embodiment, a catheter electrode comprises an electrode body defining a cavity therein, the cavity comprising a first diameter; and a spring disposed within the cavity, the spring comprising a second diameter; wherein the first diameter is equal to the second diameter. 1. A catheter electrode comprising:an electrode body defining a cavity therein, the cavity comprising a first diameter; anda spring disposed within the cavity, the spring comprising a second diameter;wherein the first diameter is equal to the second diameter.2. The catheter electrode of claim 1 , wherein the electrode body is flexible.3. The catheter electrode of claim 1 , wherein the first diameter comprises a diameter of the cavity.4. The catheter electrode of claim 1 , wherein the spring comprises a plurality of turns claim 1 , wherein the plurality of turns comprises a distal-end turn and a proximal-end turn claim 1 , and wherein the second diameter comprises an outer diameter of at least one of the distal-end turn and the proximal-end turn.5. The catheter electrode of claim 4 , further comprising:a distal cap portion adjacent to the distal-end turn; anda proximal stem portion adjacent to the proximal-end turn.6. The catheter electrode of claim 5 , wherein the distal-end turn and the distal cap portion are welded together to form a first contact surface; and wherein the proximal-end turn and the proximal stem portion are welded together to form a second contact surface.7. The catheter electrode of claim 1 , wherein the catheter tip electrode is irrigated.8. The catheter electrode of claim 1 , further comprising a thermocouple or thermistor.9. The catheter electrode of claim 1 , wherein the spring has a spring rate of about 150 grams per inch or greater.10. A catheter electrode comprising:an electrode body, the electrode body defining a cavity ...

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Номер записи: 25
13-01-2022 дата публикации

Neuromodulation catheters having jacketed neuromodulation elements and related devices, systems, and methods

Номер: US20220008127A1
Автор: Don Tran, Jaime Rios, Rudy Beasley, Sina Som, Sukyoung Shin
Принадлежит: Medtronic Ardian Luxembourg SARL

A neuromodulation catheter in accordance with a particular embodiment includes an elongate shaft and a neuromodulation element operably connected to the shaft. The shaft includes a proximal hypotube segment at its proximal end portion and a jacket disposed around at least a portion of an outer surface of the hypotube segment. The jacket may be made at least partially of a polymer blend including polyether block amide and polysiloxane. The neuromodulation element includes a distal hypotube segment and a tubular jacket disposed around at least a portion of an outer surface of the distal hypotube segment. The jacket has reduced-diameter segments spaced apart along its longitudinal axis. The neuromodulation element further includes band electrodes respectively seated in the reduced-diameter segments and respectively forming closed loops extending circumferentially around the jacket.

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Номер записи: 26
14-01-2016 дата публикации

ENERGY DELIVERY DEVICES AND METHODS

Номер: US20160008066A1
Автор: DALBEC Timothy R., DANEK Christopher J., KAPLAN Gary S., Phan Huy D., Webster Noah D., WIZEMAN William J.
Принадлежит:

This relates to methods and devices for achieving contact between the wall of a cavity or passageway and a medical device when used in tortuous anatomy. 125-. (canceled)26. A medical device , comprising:a catheter extending from a proximal end toward a distal end, the catheter including an inflow lumen and an outflow lumen separate from the inflow lumen;a balloon at the distal end of the catheter, the balloon being movable between a collapsed configuration and an expanded configuration; anda first electrode disposed on an outer surface of the balloon, the first electrode being configured to contact tissues defining a body lumen when the balloon is in the expanded configuration, the first electrode being configured to deliver radiofrequency energy to the tissues defining the body lumen, wherein the inflow lumen is configured to deliver a fluid to the balloon, and the outflow lumen is configured to simultaneously convey the fluid from the balloon, the first electrode extending around the circumference of the balloon for an arc length that is less than 180 degrees.27. The medical device of claim 26 , wherein the first electrode is one of a plurality of electrodes disposed on the outer surface of the balloon.28. The medical device of claim 27 , wherein adjacent electrodes of the plurality of electrodes are circumferentially spaced from one another by an arc length of 70 to 110 degrees.29. The medical device of claim 27 , wherein adjacent electrodes of the plurality of electrodes are spaced from one another by an arc length of 45 to 75 degrees.30. The medical device of claim 27 , wherein adjacent electrodes of the plurality of electrodes are spaced from one another by an arc length of 33 to 57 degrees.31. The medical device of claim 26 , wherein delivering the fluid into the balloon inflates the balloon.32. The medical device of claim 26 , wherein the catheter further includes an activation lumen separate from both the inflow lumen and the outflow lumen claim 26 , and ...

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Номер записи: 27
14-01-2021 дата публикации

Medical device and treatment method

Номер: US20210007790A1
Автор: Tomoaki Takemura, Yukitoshi Kato, Yusuke Takahashi
Принадлежит: Terumo Corp

A medical device and a treatment method, in which energy is accurately applied to a target site by suppressing a positional displacement between an expansion body and a biological tissue. The medical device includes an elongated shaft portion and an expansion body disposed in a distal portion of the shaft portion and configured to expand and contract in a radial direction. The expansion body includes a holding portion having a proximal side holding portion and a distal side holding portion configured to hold the biological tissue, and a movable portion configured to open and close the holding portion.

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Номер записи: 28
14-01-2021 дата публикации

Medical device

Номер: US20210007791A1
Автор: Nozomu Yamazaki, Tomoaki Takemura, Yukitoshi Kato, Yusuke Takahashi
Принадлежит: Terumo Corp

A medical device is disclosed which can suppress torsion of a wire in a circumferential direction in an expansion body formed using the wire. The medical device includes an elongated shaft portion, and an expansion body disposed in a distal portion of the shaft portion, the expansion body configured to expand and contract in a radial direction. The expansion body has wire portions in which a distal portion and a proximal portion are linked with the shaft portion, and a holding portion formed using at least one of the wire portions, and holding a biological tissue. At least one of a proximal side and a distal side of the holding portion has an opening portion formed using a wire portion or formed using a plurality of the wire portions. When the expansion body expands, the wire portion forming the holding portion faces the opening portion.

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Номер записи: 29
11-01-2018 дата публикации

MAGNETIC NAVIGATION SYSTEMS AND METHODS

Номер: US20180008342A1
Автор: Ibrahim Tamer, Swanson David K.
Принадлежит:

Systems and methods for forming a lesion on an endocardial tissue of a patients heart involve placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, and placing a guiding assembly outside of the heart. An ablation assembly includes an ablation element and a first attraction element, and a guiding assembly includes a second attraction element. First and second attraction elements can be attracted via magnetism. Techniques involve forming an ablation on the cardiac tissue of a patient's heart with an ablation element of the ablation assembly. Optionally, techniques may include moving the second attraction element of the guiding assembly relative to the patient's heart, so as to effect a corresponding movement of the ablation element of the ablation assembly. 1placing an ablation assembly inside of the heart and adjacent to the endocardial tissue, the ablation assembly comprising an ablation element, a support structure, and a first attraction element;placing a guiding assembly outside of the heart, the guiding assembly comprising a second attraction element, such that a magnetic attraction is present between the first and second attraction elements, and the support structure of the ablation assembly forms a space between the ablation element and the endocardial tissue; andforming the lesion on the endocardial tissue of the patient's heart with the ablation element of the ablation assembly while the support structure isolates the ablation element from blood flowing in the patient's heart.. A method of forming a lesion on an endocardial tissue of a patients heart, comprising: This application is a continuation of U.S. application Ser. No. 131862,996 filed Apr. 15, 2013, which is a continuation of U.S. patent application Ser. No. 12/781,072 filed May 17, 2010 (now U.S. Pat. No. 8,430,875 issued Apr. 30, 2013) entitled “MAGNETIC NAVIGATION SYSTEMS AND METHODS,” which is a nonprovisional application of, and claims the benefit of the filing ...

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Номер записи: 30
08-01-2015 дата публикации

Electrode Assembly For Catheter System

Номер: US20150011991A1
Автор: Buysman John Jason, Dakin Gregory James
Принадлежит:

In an electrode assembly for a catheter system, a plurality of struts extends from a proximal end to a distal end of the electrode assembly. Each strut has a longitudinally extending proximal leg, a longitudinally extending distal leg, and a center segment extending between and interconnecting the proximal leg and the distal leg. A hinge interconnects the proximal leg and the center segment, and another hinge interconnects the distal leg and the center segment. The center segment of each of the struts has a corresponding electrode thereon. The electrode assembly is configurable between a collapsed configuration and an expanded configuration, with the electrodes being transversely spaced from the longitudinal axis of the electrode assembly a greater distance in the expanded configuration than in the collapsed configuration. 1. An electrode assembly for an electrode catheter system , the electrode assembly having a longitudinal axis , a proximal end and a distal end , the electrode assembly comprising:first and second struts each extending from the proximal end to the distal end of the electrode assembly and having a corresponding electrode disposed thereon intermediate said proximal and distal ends of the electrode assembly, wherein the electrode assembly is configurable between a collapsed configuration and an expanded configuration, the electrodes being transversely spaced from the longitudinal axis of the electrode assembly a greater distance in the expanded configuration than in the collapsed configuration, in the collapsed configuration the electrode on the first strut being at a first longitudinal position intermediate the proximal and distal ends of the electrode assembly and the electrode on the second strut being at a second longitudinal position intermediate the proximal and distal ends of the electrode assembly and different from the first longitudinal position of the electrode on the first strut, in the expanded configuration the first longitudinal ...

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Номер записи: 31
03-02-2022 дата публикации

Controlled and precise treatment of cardiac tissues

Номер: US20220031378A1
Автор: Landy Toth, Robert S. Schwartz
Принадлежит: Individual

Compositions, systems, devices, and methods for performing precise chemical treatment of tissues are disclosed. Systems, devices, and methods for administering a chemical agent to one or more a precise regions within a tissue mass are disclosed. Compositions, systems, devices, and methods for treating targeted regions within a tissue mass are disclosed. Systems, devices, and methods for identifying, localizing, monitoring neural traffic in the vicinity of, quantifying neural traffic in the vicinity of, and mapping neural traffic near targeted regions within a tissue mass are disclosed.

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Номер записи: 32
03-02-2022 дата публикации

Cautious irreversible-electroporation (ire) protocol for avoiding bubble generation

Номер: US20220031387A1
Автор: Assaf Govari
Принадлежит: Biosense Webster Israel Ltd

An irreversible electroporation (IRE) includes setting an initial IRE protocol for applying IRE pulses by electrodes of a catheter placed in contact with tissue in an organ. A notification is issued to a user upon determining that the initial IRE protocol is expected to cause bubbles in blood. In response to the notification, user input is received from the user, that selects between the initial IRE protocol and an alternative protocol that is not expected to cause the bubbles. The IRE pulses are applied according to the initial IRE protocol or the alternative IRE protocol, depending on the user input.

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Номер записи: 33
17-01-2019 дата публикации

APPARATUS FOR EFFECTIVE ABLATION AND NERVE SENSING ASSOCIATED WITH DENERVATION

Номер: US20190015002A1
Автор: Almany Steven, FISCHELL DAVID R., FISCHELL TIM A., Ghazarossian Vartan, John Michael Sasha
Принадлежит:

An intravascular catheter for nerve activity ablation and/or sensing includes one or more needles advanced through supported guide tubes (needle guiding elements) which expand to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the extra-luminal tissue including the media, adventitia and periadvential space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Electrodes near the distal ends of the needles allow sensing of nerve activity before and after attempted renal denervation. In a combination embodiment ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media. 1. A catheter for sensing the activity from nerves outside of the lumen of a target vessel of a human body comprising:a catheter body having a distal end for insertion into a patient, a proximal end for controlling the movement of at least one needle, and a central axis extending in a longitudinal direction;a connector configured to connect to external electronic equipment outside of a proximal end of the catheter, said equipment having a sensing subsystem configured for sensing local nerve activity within a patient, and configured to be connected to at least one additional electrode in electrical contact with the patient;at least one needle guiding element adapted to expand outwardly from the catheter body toward the interior wall of the target vessel;at least one needle, the needle having at least one distal electrode, the needle adapted to be advanced outwardly, guided by the at least one needle guiding element to penetrate and advance through the interior wall of the ...

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Номер записи: 34
21-01-2021 дата публикации

Intravascular catheter with peri-vascular nerve activity sensors

Номер: US20210015381A1
Автор: David R. Fischell, Steven ALMANY, Tim A. Fischell, Vartan Ghazarossian
Принадлежит: Ablative Solutions Inc

An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. The addition of an injection lumen at the proximal end of the catheter and openings in the needles adds the functionality of ablative fluid injection into the perivascular space for an integrated nerve sending and ablation capability.

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Номер записи: 35
21-01-2021 дата публикации

METHOD FOR PAINLESS RENAL DENERVATION USING A PERI-VASCULAR TISSUE ABLATION CATHETER WITH SUPPORT STRUCTURES

Номер: US20210015518A1
Автор: Burke Jeff Alan, Denison Andy Edward, FISCHELL DAVID R., Fischell Robert E., FISCHELL TIM A., Hayden Christopher Scott, Johnson Eric Thomas, Kent Darrin James, Ragland Robert Ryan
Принадлежит:

An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall. A method can involve injection/infusion of the ablative fluid over an extended time period of at least 10 seconds or with two injections at two different penetration depths to reduce or eliminate patient pain during ablation. 122-. (canceled)23. A transvascular method of minimizing pain during the treatment of extravascular tissue , comprising:providing a catheter having an elongate flexible body, a proximal end, a distal end, and a needle disposed within a lumen of a guide tube;transvascularly positioning the distal end of the catheter at a treatment site;deploying the needle into the vessel wall at a depth of more than 0.5 mm from an inside surface of the vessel wall while maintaining the guide tube against the vessel wall;desensitizing pain nerves by injecting an anesthetic agent through the needle; andablating sympathetic nerves by injecting an ablative agent through the needle.24. The transvascular method of claim 23 , further comprising deploying at least three needles into the vessel wall.25. The transvascular method of claim 24 , wherein the depth is between 0.5 mm and 4 mm. ...

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Номер записи: 36
21-01-2021 дата публикации

Ablation lesion quality

Номер: US20210015549A1
Автор: Ali Haghighi-Mood, Richard Jonathan Cohen
Принадлежит: Sirona Medical Technologies Inc

Improved ablation procedures and exemplary catheters for use with such procedures are provided. In one example, high quality homogenous lesions with well-defined borders can be created by introducing into a patient body a catheter that includes an electrode that is mounted on a distal end of the catheter, positioning the electrode to be in contact with tissue to be ablated such that at least 65 percent of an exposed distal surface area of the electrode is in contact with the tissue to be ablated, and applying electrical energy to the electrode sufficient to create an ablation lesion in the tissue.

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Номер записи: 37
22-01-2015 дата публикации

Ablation Mesh

Номер: US20150025531A1
Автор: Gittard Shaun D., Surti Vihar C.
Принадлежит: Cook Medical Technologies LLC

An ablation device and a method of ablating a tissue are provided. The ablation device includes a tubular member having a proximal portion, a distal portion, a lumen extending at least partially therethrough and a conductive portion. The tubular member has a first configuration and a second configuration. The ablation device includes a distal cap operably connected to the distal portion having a diameter that is smaller than a diameter of a distal end portion of an endoscope and a proximal ring connected to the proximal portion having a diameter greater than a diameter of the distal end portion. The ablation device also includes a first catheter operably connected to the distal cap and a second catheter operably connected to the proximal ring, where the proximal ring is movable relative to the distal cap to move the tubular member between the first configuration and the second confirmation. 1. An ablation device comprising:a tubular member having a proximal portion, a distal portion and a lumen extending at least partially therethrough, the tubular member having a first configuration and a second configuration, the tubular member comprises a conductive portion;a distal cap operably connected to the distal portion, the cap having a diameter that is smaller than a diameter of a distal end portion of an endoscope;a proximal ring connected to the proximal portion, the proximal ring having a diameter greater than a diameter of the distal end portion;a first catheter operably connected to the distal cap;a second catheter operably connected to the proximal ring;wherein the proximal ring is movable relative to the distal cap to move the tubular member between the first configuration and the second confirmation.2. The ablation device according to claim 1 , wherein the tubular member comprises a mesh.3. The ablation device according to claim 1 , further comprising a central ring positioned between the proximal ring and the distal cap.4. The ablation device according to claim ...

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Номер записи: 38
31-01-2019 дата публикации

SYSTEMS AND METHODS FOR SELECTING, ACTIVATING, OR SELECTING AND ACTIVATING TRANSDUCERS

Номер: US20190029608A1
Автор: Moisa Saar, WEBER Michael Hermann
Принадлежит:

A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation. 1. A medical device system comprising:a data processing device system;an input-output device system communicatively connected to the data processing device system; anda memory device system communicatively connected to the data processing device system and storing a program executable by the data processing device system, the program comprising:communication instructions configured to cause the data processing device system to communicate, via the input-output device system, with an electrode-based device system comprising a structure and a plurality of electrodes arrangeable in a three dimensional distribution on the structure, the structure and the plurality of electrodes locatable within a bodily cavity;first display instructions configured to cause the input-output device system to display information regarding at least the electrode-based device system, the displayed information including a graphical representation of at least a portion of the electrode-based device system, the graphical ...

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Номер записи: 39
31-01-2019 дата публикации

SYSTEMS AND METHODS FOR SELECTING, ACTIVATING, OR SELECTING AND ACTIVATING TRANSDUCERS

Номер: US20190029609A1
Автор: Moisa Saar, WEBER Michael Hermann
Принадлежит:

A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation. 1. A medical device system comprising:a data processing device system;an input-output device system communicatively connected to the data processing device system; anda memory device system communicatively connected to the data processing device system and storing a program executable by the data processing device system, the program comprising:communication instructions configured to cause the data processing device system to communicate, via the input-output device system, with an electrode-based device system comprising a structure and a plurality of electrodes arrangeable in a three dimensional distribution on the structure, the structure and the plurality of electrodes locatable within a bodily cavity, and the structure including a first domed portion and a part other than the first domed portion;first display instructions configured to cause the input-output device system to display information regarding at least the electrode-based device system, the displayed information including a ...

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Номер записи: 40
31-01-2019 дата публикации

Expandable elements for delivery of electric fields

Номер: US20190030328A1
Автор: Brian T. HOWARD, Mark T. Stewart
Принадлежит: MEDTRONIC INC

A method, system, and device for electroporation. A system may include a medical device with a plurality of electrodes borne on an expandable element and an energy generator in communication with the electrodes. The energy generator may have processing circuitry configured to selectively deliver electroporation energy to at least one of the electrodes. The processing circuitry may determine whether an alert condition is present and, if so, cease the delivery of electroporation energy to one or more electrodes identified as the cause of the alert condition and/or prevent the delivery of electroporation energy to the one or more electrodes identified as the cause of the alert condition. The energy generator may also be configured to deliver electroporation energy in a sequence of a plurality of energy delivery patterns to enhance lesion formation.

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Номер записи: 41
04-02-2021 дата публикации

CONGESTIVE OBSTRUCTION PULMONARY DISEASE (COPD)

Номер: US20210030470A1
Автор: Callas Peter, Ortiz Mark, Pearson Robert
Принадлежит: ANGIODYNAMICS, INC.

A method for treating Chronic Obstructive Pulmonary Disease (COPD) or chronic bronchitis to alleviate the discomforts of breathing by using non-thermal electroporation energy to ablate diseased portions of the lung including the bronchus, airways and alveoli which, in effect, opens the restrictive diseased portions thereby maximizing the overall surface area thereof causing improved airflow and uninhibited breathing. 1. A method of treating lung tissue comprising:obtaining access to the lung, wherein the lung comprises a target region and wherein the access comprises advancing at least one energy delivery device through the trachea, the at least one energy delivery device comprising an expandable member configured to expand an electrode;positioning the at least one energy delivery device within an airway of the target region, wherein the energy delivery device is coupled to an energy source;expanding the expandable member to expand the electrode, andapplying electrical pulses via the expanded electrode sufficient to irreversibly electroporate the target region.2. The method of claim 1 , wherein the step of positioning the at least one energy delivery device comprises:positioning the at least one energy delivery device within a diseased region of an inner wall of a bronchus of the lung.3. The method of claim 1 , wherein the step of positioning the at least one energy delivery device comprises:inserting the at least one energy delivery device within a diseased region of an alveolus of the lung.4. The method of claim 2 , wherein the step of inserting the at least one energy delivery device comprises:advancing the at least one energy delivery device through a patient's trachea prior to inserting the at least one energy delivery device within a diseased region of the bronchus.5. The method of claim 3 , wherein the step of inserting the at least one energy delivery device comprises:obtaining access percutaneously prior to inserting the at least one energy delivery device ...

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Номер записи: 42
08-02-2018 дата публикации

ENERGY DELIVERY DEVICES AND METHODS

Номер: US20180036073A1
Автор: DALBEC Timothy R., DANEK Christopher J., KAPLAN Gary, Phan Huy D., Webster Noah D., Wizeman William
Принадлежит:

This relates to methods and devices for achieving contact between the wall of a cavity or passageway and a medical device when used in tortuous anatomy. 125-. (canceled)26. A method of treating a lung , the method comprising:stimulating tissue surrounding an airway of the lung to constrict the airway by contacting the tissue with a pharmacological agent;after stimulating the tissue, measuring a parameter of the airway;identifying a treatment site based on the measured parameter by selecting the contacted tissue to receive energy from an electrode;delivering a liquid to the airway and exterior of the medical device to electrically couple the electrode to the contacted tissue;applying energy to the contacted tissue from the electrode, through the liquid, to damage nerve tissue while simultaneously delivering the liquid to and withdrawing the liquid from the airway to absorb heat from the contacted tissue, andafter applying energy to the contacted tissue, determining an effectiveness of the applying energy to the contacted tissue by determining whether the contacted tissue has a reduced ability to respond to a stimulus as compared to an ability to respond to the stimulus prior to the applying energy.27. The method of claim 26 , further including damaging the contacted tissue.28. The method of claim 27 , wherein the contacted tissue includes mucosal tissue.29. The method of claim 26 , wherein applying energy includes applying RF energy.30. The method of claim 26 , wherein the pharmacological agent is a bronchoconstricting agent.31. The method of claim 30 , wherein the bronchoconstricting agent is histamine or methacholine.32. A method of treating a lung claim 30 , the method comprising:circulating a liquid between an interior of a medical device, and exterior of the medical device within an airway of the lung, the medical device including a catheter and an electrode, to electrically couple the electrode to tissue surrounding the airway; andwhile circulating the liquid, ...

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Номер записи: 43
08-02-2018 дата публикации

MEDICAL DEVICE FOR USE IN BODILY LUMENS, FOR EXAMPLE AN ATRIUM

Номер: US20180036074A1
Автор: Gelbart Daniel, GOERTZEN Douglas Wayne, Lopes Fernando Luis de Souza
Принадлежит:

A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s). 134-. (canceled)35. A medical device comprising:a plurality of transducer element sets;an expandable frame comprising a proximal end and a distal end; anda plurality of flexible circuit strips, an elongated portion of each flexible circuit strip extending between the proximal and the distal ends of the expandable frame, each flexible circuit strip including a respective length of the respective elongated portion of the flexible circuit strip between the proximal and the distal ends of the expandable frame, and each flexible circuit strip comprising at least a first printed circuit board substrate and a set of one or more electrically conductive traces patterned on at least a portion of the first printed circuit board substrate and electrically coupled to a respective one of the transducer element sets,wherein a portion of the medical device is selectively movable between an unexpanded configuration in which the portion of the medical device is sized to be delivered percutaneously to a bodily cavity with the distal end of the expandable frame positioned to be introduced into the bodily cavity prior to the proximal end of the ...

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Номер записи: 44
08-02-2018 дата публикации

Medical device for use in bodily lumens, for example an atrium

Номер: US20180036075A1
Автор: Daniel Gelbart, Douglas Wayne GOERTZEN, Fernando Luis De Souza Lopes
Принадлежит: Kardium Inc

A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s).

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Номер записи: 45
08-02-2018 дата публикации

MEDICAL DEVICE FOR USE IN BODILY LUMENS, FOR EXAMPLE AN ATRIUM

Номер: US20180036076A1
Автор: Gelbart Daniel, GOERTZEN Douglas Wayne, Lopes Fernando Luis de Souza
Принадлежит:

A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wail of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascular guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s). 1. (canceled)2. A medical system comprising:a catheter shaft;an expandable frame comprising a proximal end portion and a distal end portion, at least the proximal end portion of the expandable frame coupled to an end portion of the catheter shaft, the expandable frame having a first size, in a delivery configuration, configured to allow percutaneous or intravascular delivery of the expandable frame to a bodily cavity, the expandable frame, in an expanded configuration, having a second size greater than the first size, and the expandable frame in the expanded configuration configured to fit within the bodily cavity; anda plurality of flexible circuit strips including a plurality of transducer elements, the plurality of flexible circuit strips supported by the expandable frame, each flexible circuit strip of the plurality of flexible circuit strips including an electrically insulative substrate and electrically conductive traces patterned on at least a portion of the electrically insulative substrate, each flexible circuit strip including a respective longitudinal portion extending between the proximal end portion and the distal end ...

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Номер записи: 46
08-02-2018 дата публикации

MEDICAL DEVICE FOR USE IN BODILY LUMENS, FOR EXAMPLE AN ATRIUM

Номер: US20180036077A1
Автор: Gelbart Daniel, GOERTZEN Douglas Wayne, Lopes Fernando Luis de Souza
Принадлежит:

A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s). 1. (canceled)2. A medical system comprising:a catheter shaft;an expandable frame comprising a proximal end portion and a distal end portion, at least the proximal end portion of the expandable frame coupled to an end portion of the catheter shaft, the expandable frame having a first size, in a delivery configuration, configured to allow percutaneous or intravascular delivery of the expandable frame to a bodily cavity, the expandable frame, in an expanded configuration, having a second size greater than the first size, and the expandable frame in the expanded configuration configured to fit within the bodily cavity; andat least a first ablation electrode set supported by the expandable frame and constructed as at least part of a flexible circuit strip including at least a first electrically insulative substrate and at least one electrically conductive trace, each ablation electrode of the first ablation electrode set selectively operable to transmit energy sufficient to cause tissue ablation and patterned on at least a portion of the first electrically insulative substrate, each particular ablation electrode of the first ablation ...

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Номер записи: 47
07-02-2019 дата публикации

METHOD FOR ANALYSIS OF COMPLEX RHYTHM DISORDERS

Номер: US20190038157A1
Автор: Narayan Sanjiv M., Rappel Wouter-Jan
Принадлежит: The Regents of the University of California

A method of analyzing a complex rhythm disorder in a human heart includes accessing signals from a plurality of sensors disposed spatially in relation to the heart, where the signals are associated with activations of the heart, and identifying a region of the heart having an activation trail that is rotational or radially emanating, where the activation trail is indicative of the complex rhythm disorder and is based on activation times associated with the activations of the heart. 1. A method for analyzing a source of a complex heart rhythm disorder in a patient , the method comprising:collecting signals generated by a catheter assembly having a plurality of sensors positioned to detect cardiac activations at a plurality of locations associated with the patient's heart over a time period corresponding to a plurality of heart beats; identifying within each collected signal an activation onset of a heart beat detected by a sensor corresponding to a location of the plurality of locations;', 'organizing a sequence of activation onsets for the plurality of sensors based on one or more of occurrence over the time period and positions of the sensors to generate an activation trail;', 'determining a sensor map corresponding to the plurality of sensor locations; and', 'associating the activation trail with the sensor map to determine whether a discernible signature pattern is generated;', "if a discernible signature pattern is generated, determining at least one approximate core region, wherein the discernible signature pattern and the at least one approximate core region are indicative of a type of heart rhythm disorder and its location within the patient's heart; and"], 'inputting data comprising the collected signals and the plurality of locations into a computer processor configured for analyzing the signals bydisplaying a clinical representation of the discernible signature pattern and the at least one approximate core region on a graphical display device, wherein the ...

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Номер записи: 48
07-02-2019 дата публикации

Ablation check pulse routine and integration for electroporation

Номер: US20190038171A1
Автор: Brian T. HOWARD
Принадлежит: MEDTRONIC INC

Devices, systems, and methods relating to a low-voltage, pre-treatment pulse routine for evaluating a potential for non-target tissue damage from the delivery of energy, such as electroporation energy to an area of target tissue. In one embodiment, a medical system includes a medical device having a treatment element; and a control unit in communication with the medical device, the control unit being configured to: deliver a low-voltage, pre-treatment pulse routine through the treatment element to an area of target tissue; determine whether the low-voltage, pre-treatment pulse routine has a stimulation effect on an area of non-target tissue; and deliver an ablation energy routine through the treatment element to the area of target tissue when the control unit determines that the low-voltage, pre-treatment pulse routine does not have a stimulation effect on the area of non-target tissue.

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Номер записи: 49
07-02-2019 дата публикации

TISSUE ABLATION AND MONITORING THEREOF

Номер: US20190038350A1
Автор: Claude John P., SALAHIEH Amr, SAUL Tom
Принадлежит:

An ablation catheter including an elongate shaft, an inflatable balloon positioned at a distal region of the elongate shaft, a first ablation electrode disposed outside of and carried by an outer surface of the inflatable balloon, a first ultrasound transducer disposed outside of the inflatable balloon, and a flexible circuit. The flexible circuit includes a first conductor and a second conductor and is disposed outside of and carried by the outer surface of the inflatable balloon. The first conductor is in electrical communication with the first ablation electrode, and the second conductor in electrical communication with the first ultrasound transducer. 1. An ablation catheter , comprising:an elongate shaft;an inflatable balloon positioned at a distal region of the elongate shaft;a first ablation electrode disposed outside of and carried by an outer surface of the inflatable balloon;a first ultrasound transducer disposed outside of the inflatable balloon; anda flexible circuit, including a first conductor and a second conductor, disposed outside of and carried by the outer surface of the inflatable balloon, the first conductor in electrical communication with the first ablation electrode, and the second conductor in electrical communication with the first ultrasound transducer.2. The ablation catheter of claim 1 , wherein the first ultrasound transducer is positioned within a periphery of the first ablation electrode.3. The ablation catheter of claim 1 , wherein the first ultrasound transducer is disposed under the first ablation electrode.4. The ablation catheter of claim 1 , wherein the first ultrasound transducer is an ultrasound receiver.5. The ablation catheter of claim 1 , wherein the first ultrasound transducer is an ultrasound emitter.6. The ablation catheter of claim 1 , wherein the first ultrasound transducer is at least partially surrounded by an insulation layer.6. The ablation catheter of claim 1 , further comprising:a second ultrasound transducer ...

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Номер записи: 50
12-02-2015 дата публикации

EXPANDABLE CATHETER AND RELATED METHODS OF MANUFACTURE AND USE

Номер: US20150045788A1
Автор: BYRNE TJ, LEVENDUSKY JOSEPH A., Litscher Eric Karl, MANNION Paul, Nguyen Man Minh
Принадлежит:

A medical device may include an expandable energy delivery array reciprocally movable between a first configuration and a second configuration. The expandable energy delivery array may include a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces, and a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces. The second proximal end piece may be proximal to the first proximal end piece and the second distal end piece may be distal to the first distal end piece. 1. A medical device , comprising: a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces; and', 'a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces, wherein the second proximal end piece is proximal to the first proximal end piece, and the second distal end piece is distal to the first distal end piece., 'an expandable energy delivery array reciprocally movable between a first configuration and a second configuration, the expandable energy delivery array comprising2. The medical device of claim 1 , wherein the first and second assemblies are electrically insulated from one another.3. The medical device of claim 1 , wherein the first and second proximal end pieces are separated by an insulating element.4. The medical device of claim 3 , wherein the first and second proximal end pieces are longitudinally separated by the insulating element.5. The medical device of claim 1 , wherein the first and second distal end pieces are longitudinally separated by an insulating ...

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Номер записи: 51
15-02-2018 дата публикации

ELECTROSURGICAL (RF) MEDICAL INSTRUMENTS FOR CUTTING AND COAGULATING TISSUE

Номер: US20180042658A1
Автор: Aronhalt Taylor W., Baxter, Houser Kevin L., Hunt John V., III Chester O., IV Frederick E., Mallow Jennifer M., Shelton, Strobl Geoffrey S., Worrell Barry C., Yates David C.
Принадлежит:

An electrosurgical device is disclosed. The electrosurgical device includes a handle, a shaft extending distally from the handle, and an end effector coupled to a distal end of the shaft. The end effector comprises a first electrode and a second electrode. The second electrode includes a first position and a second position. The second electrode is configured to move from the first position to the second position when a force is applied to the end effector by a tissue section. The first electrode and the second electrode define a treatment area when the second electrode is in the second position. 1. An electrosurgical instrument comprising:a pencil-grip handle;a shaft coupled to the pencil grip handle; and a body;', 'a source electrode; and', 'one or more return electrodes,, 'an end effector coupled to the shaft, wherein the end effector compriseswherein the source electrode and the one or more return electrodes are configured to provide an electrosurgical signal to a tissue.2. The electrosurgical instrument of claim 1 , wherein the electrosurgical signal comprises a radio frequency (RF) signal.3. The electrosurgical instrument of claim 1 , wherein the pencil-grip handle comprises a power source and is cordless.4. The electrosurgical instrument of claim 1 , wherein the source electrode is disposed on a center portion of the body and the one or more return electrodes are disposed on a lateral portion of the body.5. The electrosurgical instrument of claim 1 , wherein the body defines an oval shape.6. The electrosurgical instrument of claim 1 , wherein the one or more return electrodes each comprise a first return electrode and a second return electrode.7. The electrosurgical instrument of claim 6 , further comprising an electrosurgical generator coupled to the end effector claim 6 , wherein the electrosurgical generator is configured to produce the electrosurgical signal comprising a first phase claim 6 , a second phase claim 6 , and a third phase claim 6 , wherein ...

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Номер записи: 52
15-02-2018 дата публикации

SYSTEMS, APPARATUSES, AND METHODS FOR TREATING TISSUE AND CONTROLLING STENOSIS

Номер: US20180042668A1
Автор: DEEM Mark E., Dimmer Steven C., GIFFORD, III Hanson S., Mayse Martin L.
Принадлежит:

Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input. The system, delivery devices, and methods can damage tissue and manage scarring and stenosis. 1. An energy delivery device , comprising:a catheter shaft; a cooling element movable from a collapsed state to an expanded state, and', 'an intercartilaginous energy emitter including a plurality of electrodes circumferentially offset from one another about a longitudinal axis of the ablation assembly, the electrodes being configured to delivery energy to a plurality of target regions of an airway that are spaced apart from one another with respect to a longitudinal axis of the ablation assembly, and wherein the energy emitter and the cooling element are configured to cooperate to form intercartilaginous lesions which are spaced apart from surface tissue of the airway and positioned between cartilaginous rings of the airway., 'and an ablation assembly coupled to the catheter shaft and including'}251-. (canceled) This application is a continuation of application Ser. No. 14/872,212 filed Oct. 1, 2015, which in turn is a continuation of application Ser. No. 13/509,581 filed Aug. 14, 2012, now U.S. Pat. No. 9,149,328 issued Oct. 6, 2015, which is a 371 of PCT/US10/56424 filed Nov. 11, 2010 which claims the benefit of U.S. Provisional Application No. 61/260,349 filed Nov. 11, 2009, each of which is hereby fully incorporated herein by reference.The present invention generally relates to systems, apparatuses, and methods for treating tissue, and more particularly, the invention relates to systems, apparatuses, and methods for eliciting a desired response while controlling stenosis.Pulmonary diseases may cause a wide range of problems ...

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Номер записи: 53
03-03-2022 дата публикации

Fitting and Directing an Expandable Catheter Based on Automatic Pulmonary Veins Anatomical Characterization

Номер: US20220061914A1
Автор: Adawi Eid, Dekel Zvi, Massarwi Fady, Rosenberg Avigdor
Принадлежит:

A method includes, using anatomical data, calculating multiple cross-sectional shapes of a lumen of an organ in a body of a patient at multiple respective positions on a medial axis of the lumen. One or more of the positions on the medial axis are identified, at which a given expandable frame of a catheter would fit the cross-sectional shapes. The one or more identified positions are presented to a user. 1. A method , comprising:using anatomical data, calculating multiple cross-sectional shapes of a lumen of an organ in a body of a patient at multiple respective positions on a medial axis of the lumen;identifying one or more of the positions on the medial axis, at which a given expandable frame of a catheter would fit the cross-sectional shapes; andpresenting the one or more identified positions to a user.2. The method according to claim 1 , wherein the one or more identified positions comprise a contiguous range of positions on the medial axis of the lumen.3. The method according to claim 1 , wherein the calculated cross-sectional shapes are orthogonal to the medial axis at the respective positions.4. The method according to claim 1 , wherein the cross-sectional shapes are oval.5. The method according to claim 4 , wherein identifying the positions comprises fitting the cross-sectional shapes to respective ellipses claim 4 , and identifying the one or more positions for which the ellipses have an ovality index larger than a predefined value claim 4 , wherein the ovality index is defined as maximal for a circle.6. The method according to claim 1 , further comprising claim 1 , for at least one of the identified positions claim 1 , presenting to the user an indication indicative of a diameter of the expandable frame of the catheter that would fit a cross-sectional shape of the lumen.7. The method according to claim 1 , wherein presenting the identified positions comprises marking the one or more identified positions on a medial cross-section diagram of the lumen.8. The ...

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Номер записи: 54
14-02-2019 дата публикации

Coronary sinus electrophysiology measurements device and methods

Номер: US20190046062A1
Автор: Dima Pinhasov, Lior Yankelson, Omer Shezifi
Принадлежит: Medical Research Infrastructure and Health Services Fund of the Tel Aviv Medical Center

An electrode array configured to be inserted at least partially into a blood vessel including: a self-expandable array body; at least two axially spaced-apart electrodes connected to said array body; wherein at least part of said array body expands to an open conformation and pushes at least one selected electrode against a blood vessel inner tissue with a force designed not to damage venous tissue.

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Номер записи: 55
25-02-2021 дата публикации

CATHETER AND RECANALIZATION CATHETER SYSTEM

Номер: US20210052321A1
Автор: HASE Yukiko, HORI Takayuki, Katoh Osamu, Ogata Wayne, SAKATA Kensuke
Принадлежит: ASAHI INTECC CO., LTD.

A catheter comprises a shaft, an extended shaft portion, and an electrode disposed on an outer circumferential surface of the shaft. The shaft has a first lumen and a second lumen that is arranged adjacent to the first lumen. The extended shaft portion is provided on a distal end portion of the shaft, has the first lumen, and has a distal end portion located on a distal end side of a distal end portion of the second lumen, in the shaft. 1. A catheter comprising:a shaft having a first lumen and a second lumen arranged adjacent to the first lumen in a radial direction of the shaft;an extended shaft portion that is provided on a distal end portion of the shaft and extends in a longitudinal direction of the shaft, the extended shaft portion having the first lumen and a distal end portion located on a distal end side of a distal end portion of the second lumen in the shaft; andan electrode disposed on an outer circumferential surface of the shaft.2. The catheter according to claim 1 , wherein a first opening formed in the distal end portion of the extended shaft portion, the first opening communicating with the first lumen; and', 'a second opening formed on a proximal end side of the first opening in the extended shaft portion and in a side face of the extended shaft portion on a side opposed to the second lumen, the second opening communicating with the first lumen, and, 'the extended shaft portion further comprisesthe shaft comprises a third opening formed in the distal end portion of the shaft, the third opening communicating with the second lumen.3. The catheter according to claim 1 , whereinthe shaft further comprises a fourth opening formed in a side face of the shaft on a proximal end side of the third opening, the fourth opening communicating with the second lumen.4. The catheter according to claim 1 , further comprisingan expanding/contracting portion disposed in the extended shaft portion, the expanding/contracting portion being configured to expand and ...

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Номер записи: 56
10-03-2022 дата публикации

Flex Circuit and Surface Mounted Electrode Catheter

Номер: US20220071695A1
Автор: Beeckler Christopher Thomas, Govari Assaf, Keyes Joseph Thomas
Принадлежит:

In one embodiment, a medical system includes a catheter to be inserted into a body part, and including an elongated deflectable element including a distal end, a proximal coupler connected to the distal end, an expandable assembly comprising flexible polymer circuit strips, each flexible polymer circuit strip including strip electrodes and a respective contact pad disposed thereon, the flexible polymer circuit strips having respective proximal ends connected to, and disposed circumferentially around, the proximal coupler, and surface mountable electrodes electrically connected to respective ones of the flexible polymer circuit strips, wherein each surface mountable electrode is electrically connected to the respective contact pad of a respective one of the flexible polymer circuit strips using at least one electrically conductive retainer. 1. A medical system including a catheter configured to be inserted into a body part of a living subject , and comprising:an elongated deflectable element including a distal end;a proximal coupler connected to the distal end;an expandable assembly comprising a plurality of flexible polymer circuit strips, each flexible polymer circuit strip including multiple strip electrodes and a respective contact pad disposed thereon, the flexible polymer circuit strips having respective proximal ends connected to, and disposed circumferentially around, the proximal coupler; anda plurality of surface mountable electrodes electrically connected to respective ones of the flexible polymer circuit strips, wherein each surface mountable electrode is electrically connected to the respective contact pad of a respective one of the flexible polymer circuit strips using at least one electrically conductive retainer.2. The system according to claim 1 , wherein each surface mountable electrode extends around the respective flexible polymer circuit strip.3. The system according to claim 1 , further comprising:an ablation power generator configured to be ...

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Номер записи: 57
01-03-2018 дата публикации

SYSTEM AND METHOD FOR ENDOMETRIAL ABLATION

Номер: US20180055561A1
Автор: Truckai Csaba
Принадлежит:

A wall of a uterus is ablated by expanding a structure in the uterus and applying energy across the wall of the structure into the uterine wall. An exterior surface of the structure conforms to an inner wall of the uterus, and the energy may cause vapor to collect between the wall and the structure. The vapor is released by providing a barrier to release which is inflated at a pressure above which the barrier at least partially collapses to allow the vapor to leave the uterus. 1. An electrosurgical ablation probe comprising:a shaft having a proximal end, a distal end, and a gas flow passage with an opening near a distal end of the shaft;a dielectric wall having an interior surface, an exterior surface, and an interior volume surrounding the distal end of the shaft;a barrier element in the flow passage, said barrier configured to open when a gas pressure in the interior volume falls below a predetermined pressure and close when said gas pressure in the interior volume rises above the predetermined pressure;a first electrode structure disposed within the gas flow passage; anda second electrode structure disposed on an exterior surface of the shaft;said first and second electrodes configured to be connected to a source of a radiofrequency voltage to initiate a plasma in an electrically non-conductive gas flowing through the flow passage into the interior volume of the dielectric wall when tissue establishes a current path between the first and second electrodes;2. An electrosurgical ablation probe as in claim 1 , wherein the barrier element is disposed in a distal end of the gas flow passage.3. An electrosurgical ablation probe as in claim 1 , wherein the barrier element is a balloon structure which is inflatable independently of the expandable structure.4. An electrosurgical ablation probe as in claim 3 , wherein the barrier element comprises a proximal portion of the expandable structure.5. An electrosurgical ablation probe as in claim 3 , further comprising an ...

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Номер записи: 58
04-03-2021 дата публикации

Mapping catheter with flex panel electrode assembly

Номер: US20210059745A1
Автор: Debby E. Highsmith
Принадлежит: Biosense Webster Israel Ltd

An apparatus includes a catheter assembly and an end effector. The catheter assembly includes an outer sheath with a distal end. The end effector is associated with a distal end of the catheter assembly. The end effector includes a panel assembly with microelectrodes for electrophysiological (EP) mapping. The microelectrodes are configured in a matrix within the panel assembly and provide multiple points of contact with the target tissue for EP mapping. The panel assembly can transition between a first contracted state and a second expanded state. The panel assembly can fit within the outer sheath in the first state. The panel assembly can expand outwardly away from a longitudinal axis defined by the catheter assembly in the second state once exposed distally relative to the distal end of the outer sheath.

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Номер записи: 59
02-03-2017 дата публикации

SELECTABLE ECCENTRIC REMODELING AND/OR ABLATION

Номер: US20170056105A1
Автор: Kelleher Brian S., Koenig Donald H., Michel Raphael M., Ross Stephen O., Steinke Tom A., Stone Corbett W.
Принадлежит:

A catheter and catheter system for eccentric remodeling and/or removal of atherosclerotic material of a blood vessel of a patient include an elongate flexible catheter body with a radially expandable structure. A plurality of electrodes or other electrosurgical energy delivery surfaces can radially engage atherosclerotic material when the structure expands. An atherosclerotic material detector near the distal end of the catheter body may measure circumferential atherosclerotic material distribution, and a power source selectively energizes the electrodes to eccentrically remodel the measured atherosclerotic material. 1. A system for remodeling tissue about a body lumen , the system comprising:(a) an energy source; and(b) a catheter coupled to the energy source, the catheter including an expandable device comprising a plurality of electrodes sequentially positioned along a length of the expandable device in a helical pattern, wherein the system is configured to remodel a target tissue while inhibiting damage to collateral tissue.2. The system of claim 1 , wherein the expandable device is configurable between an expanded condition and an unexpanded condition claim 1 , wherein claim 1 , when the expandable device is in the expanded condition claim 1 , the plurality of electrodes are in the helical pattern.3. The system of claim 2 , wherein the plurality of electrodes are positioned along an elongated body.4. The system of claim 3 , wherein the elongated body includes at least one helical loop when the expandable device is in the expanded condition.5. The system of claim 4 , wherein the elongated body includes a plurality of helical loops when the expandable device is in the expanded condition.6. The system of claim 4 , wherein the elongated body is substantially straight when the expandable device is in the unexpanded condition.7. The system of claim 3 , wherein the elongated body includes a nickel and titanium alloy.8. The system of claim 1 , wherein at least some of ...

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Номер записи: 60
04-03-2021 дата публикации

Catheter and recanalization catheter system

Номер: US20210060293A1
Автор: Kazuya Kubo, Maiko KATAOKA, Osamu Katoh, Ryotaro Kojima, Yoshiki Kaneko, Yukiko Hase
Принадлежит: Asahi Intecc Co Ltd

A catheter includes a shaft having a first lumen inside thereof, an expansion/contraction portion that is disposed on a distal end portion of the shaft and is expandable and contractible in a radial direction, and an actuation portion that expands and contracts the expansion/contraction portion. The expansion/contraction portion has a fixed portion fixed to the shaft, a sliding portion capable of sliding in a longitudinal direction of the shaft on an outer peripheral face of the shaft, and a suspension portion extending in the longitudinal direction of the shaft that connects the fixed portion with the sliding portion. When the sliding portion is slid toward the fixed portion by the actuation portion, the suspension portion expands in a radial direction of the shaft.

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Номер записи: 61
20-02-2020 дата публикации

EXPANDABLE CATHETER AND RELATED METHODS OF MANUFACTURE AND USE

Номер: US20200054391A1
Автор: BYRNE TJ, LEVENDUSKY JOSEPH A., Litscher Eric Karl, MANNION Paul, Nguyen Man Minh
Принадлежит: Boston Scientific Scirned, Inc.

A medical device may include an expandable energy delivery array reciprocally movable between a first configuration and a second configuration. The expandable energy delivery array may include a first assembly having a first proximal end piece, a first distal end piece, and one or more first energy transfer elements extending between the first proximal and first distal end pieces, and a second assembly having a second proximal end piece, a second distal end piece, and one or more second energy transfer elements extending between the second proximal and second distal end pieces. The second proximal end piece may be proximal to the first proximal end piece and the second distal end piece may be distal to the first distal end piece. 120.-. (canceled)21. A medical device , comprising: a first plurality of longitudinally extending legs formed in a first partially tubular member;', 'a second plurality of longitudinally extending legs formed in a second partially tubular member;', 'a first endpiece formed by first ends of the first and second partially tubular members; and', 'a second endpiece formed by second ends of the first and second partially tubular members, wherein a portion of the second partially tubular member is configured to be received in a portion of the first partially tubular member., 'an expandable electrode assembly reciprocally movable between a first configuration and a second configuration, the expandable electrode assembly including22. The medical device of claim 21 , wherein legs of the first partially tubular member circumferentially alternate with legs of the second partially tubular member.23. The medical device of claim 21 , wherein:the first ends of the first and second partially tubular members are substantially C-shaped,and the first endpiece is formed by inserting the first end of the second partially tubular member into a volume partially defined by the first end of the first partially tubular member.24. The medical device of claim 23 , ...

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Номер записи: 62
05-03-2015 дата публикации

Anchored RF Ablation Device for The Destruction of Tissue Masses

Номер: US20150066003A1
Автор: Adam Hagmann, Bruce Lee, Gordon Epstein, Jeffrey M. Cohen, Richard Spero
Принадлежит: Halt Medical Inc

The inventive ablation element comprises an elongated cannula having a proximal end and a distal end. The cannula defines an internal lumen and a cannula axis. A plurality of conductors contained within the lumen, each having a proximal end proximate the proximal end of the cannula, and a distal end proximate the distal end of the cannula. A plurality of ablation stylets each has a proximal end and a distal end, and each coupled to the distal end of a respective conductor, the conductors together with their respective stylets being mounted for axial movement. A trocar point defined proximate the distal end of the cannula. A deflection surface positioned between the trocar point and the proximal end of the cannula, the deflection surface being configured and positioned to deflect at least some of the stylets laterally with respect to the cannula axis in different directions defining an ablation volume.

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Номер записи: 63
28-02-2019 дата публикации

CHEMICAL MODULATION OF NERVES INNERVATING THE LIVER

Номер: US20190059969A1
Автор: Azamian Bobak Robert, Vafai Scott Bradley
Принадлежит:

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery. 1. (canceled)2. A method of altering glucose levels , the method comprising:inserting a catheter into a vasculature of a subject,wherein said catheter comprises a distal end configured to disrupt one or more nerves,advancing the distal end of the catheter to a location within a portion of a common hepatic artery of the vasculature; anddisrupting one or more nerves of a hepatic plexus surrounding the portion of the common hepatic artery to decrease a glucose level within the subject.3. The method of claim 2 , wherein the distal end comprises a cutting portion configured to transect said one or more nerves.4. The method of claim 2 , wherein the distal end comprises a compression member configured to apply mechanical compression to disrupt the one or more nerves.5. The method of claim 4 , wherein the compression member comprises a shape memory compression clip.6. The method of claim 4 , wherein the compression member comprises a vascular wall clamp.7. The method of claim 6 , wherein the catheter comprises a plurality of suction holes configured to create suction on a wall surface of the common hepatic artery.8. The method of claim 2 , wherein the distal end is configured to hold a cooling fluid configured to cryogenically disrupt said one or more nerves.9. The method of claim 8 , wherein the distal end comprises a balloon.10. The method of claim 2 , wherein the distal end comprises a delivery portion configured to deliver a chemoablative agent to ablate said one or more nerves.11. The method of ...

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Номер записи: 64
17-03-2022 дата публикации

ELONGATED MEDICAL SHEATH

Номер: US20220079654A1
Автор: Koon Lauren, Moriyama Eduardo
Принадлежит:

An elongated medical sheath is configured to be movable and positionable proximate to a biological feature of a patient. An expandable-and-collapsible support structure is configured to be selectively movable, at least in part, between an interior of the elongated medical sheath and an exterior of the elongated medical sheath. An energy-emitting assembly is supported by the expandable-and-collapsible support structure. 1. An apparatus , comprising:an elongated medical sheath configured to be movable and positionable proximate to a biological feature of a patient; andan expandable-and-collapsible support structure configured to be selectively movable, at least in part, between an interior of the elongated medical sheath and an exterior of the elongated medical sheath; andan energy-emitting assembly being supported by the expandable-and-collapsible support structure.2. The apparatus of claim 1 , wherein:{'claim-text': 'energy-emitting devices being supported by the expandable-and-collapsible support structure.', '#text': 'the energy-emitting assembly includes:'}3. The apparatus of claim 2 , wherein:{'claim-text': 'electrodes being supported by the expandable-and-collapsible support structure.', '#text': 'said energy-emitting devices include:'}4. The apparatus of claim 2 , wherein:{'claim-text': ['an expandable-and-collapsible cage structure configured to be selectively movable, at least in part, between the interior of the elongated medical sheath and the exterior of the elongated medical sheath; and', 'an elongated member extending from the expandable-and-collapsible cage structure; and', 'the elongated member is configured to be movable along the interior of the elongated medical sheath.'], '#text': 'the expandable-and-collapsible support structure includes:'}5. The apparatus of claim 4 , wherein:the expandable-and-collapsible cage structure has a distal section and a proximal section; andat least one of the energy-emitting devices is positioned at the distal ...

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Номер записи: 65
10-03-2016 дата публикации

Energy delivery devices and methods

Номер: US20160066990A1
Автор: Christopher J. Danek, Gary S. Kaplan, Timothy R. Dalbec, William J. Wizeman
Принадлежит: Asthmatx Inc

This relates to methods and devices for achieving contact between the wall of a cavity or passageway and a medical device when used in tortuous anatomy.

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Номер записи: 66
27-02-2020 дата публикации

Systems, devices, and methods for performing medical procedures in the intestine

Номер: US20200060942A1
Автор: Harith RAJAGOPALAN, J. Christopher Flaherty, Jay Caplan
Принадлежит: Fractyl Laboratories Inc

A method for performing a medical procedure in an intestine of a patient is provided. The method comprises providing a system comprising: a catheter for insertion into the intestine, the catheter comprising: an elongate shaft comprising a distal portion; and a functional assembly positioned on the shaft distal portion and comprising at least one treatment element. The catheter is introduced into the patient, and target tissue is treated with the at least one treatment element. The target tissue comprises mucosal tissue of the small intestine, and the medical procedure can be configured to treat one or more diseases or disorders based on a measured physiologic parameter of the patient.

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Номер записи: 67
08-03-2018 дата публикации

NAVIGATION WITH ARBITRARY CATHETER GEOMETRIES AND METHOD OF CONTACT ASSESSMENT

Номер: US20180064495A1
Автор: Hareland Scott A.
Принадлежит:

A method and system for determining a location of a treatment element relative to an anatomical feature and for estimating contact between the treatment element and the anatomical feature in the context of a navigation system. The system may include a medical device including at least one treatment element and at least one navigation electrode and a navigation system in communication with the one or more navigation electrodes, the navigation system including a processing unit. The processing unit may be programmed to determine a plurality of points that define a surface geometry of the at least one treatment element, calculate a distance between each of the points and a closest point on the anatomical feature, and estimate the likelihood of contact between the points. 1. A system for determining a location of a medical device relative to an anatomical feature , the system comprising: an elongate body having a distal portion, a proximal portion, and a longitudinal axis;', 'at least one treatment element coupled to the elongate body distal portion, the at least one treatment element having a surface geometry; and', 'at least one navigation electrode coupled to the elongate body distal portion; and, 'a medical device including determine a first surface of the anatomical feature;', 'determine a spatial location of each of the at least one navigation electrode;', 'calculate the surface geometry of the at least one treatment element;', 'define a plurality of points on the surface geometry of the at least one treatment element;', 'for each of the plurality of points on the surface geometry of the at least one treatment element, define a point on the first surface of the anatomical feature that is closest to a corresponding point of the plurality of points on the surface geometry of the at least one treatment element; and', 'for each defined point on the first surface of the anatomical feature, estimate a likelihood of contact between the defined point on the first surface ...

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Номер записи: 68
15-03-2018 дата публикации

METHODS OF ABLATING TISSUE USING A CATHETER INJECTION SYSTEM

Номер: US20180071019A1
Автор: FISCHELL DAVID R., FISCHELL TIM A.
Принадлежит:

At the present time, physicians often treat patients with atrial fibrillation (AF) using radiofrequency (RF) catheter systems to ablate conducting tissue in the wall of the Left Atrium of the heart around the ostium of the pulmonary veins. These systems are expensive and take time consuming to use. The present invention circular ablation system CAS includes a multiplicity of expandable needles that can be expanded around a central axis and positioned to inject a fluid like ethanol to ablate conductive tissue in a ring around the ostium of a pulmonary vein quickly and without the need for expensive capital equipment. The expansion of the needles is accomplished by self-expanding or balloon expandable structures. The invention includes centering means so that the needles will be situated in a pattern surrounding the outside of the ostium of a vein. Also included are members that limit the distance of penetration of the needles into the wall of the left atrium. The present invention also has application to ablating tissue around the ostium of a renal artery for the treatment of hypertension. 1. A method of treating atrial fibrillation , the method including the steps of:a) advancing a guiding catheter until its distal end is situated in the ostium of a pulmonary vein;b) advancing a circular ablation system catheter through a guiding catheter until the distal end of the circular ablation system lies within the pulmonary vein, the circular ablation system including a distal portion proximal to the distal end of the catheter with expandable tubes having injection needles at their distal end, the circular ablation system designed to allow injection of ablative fluid through the injection needles;c) causing the expandable tubes with distal injection needles to expand outward into the wall of the left atrium of the heart; andd) injecting ablative fluid into the wall of the left atrium through the injection needles.2. The method of where the ablative fluid is ethyl alcohol.3. ...

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Номер записи: 69
07-03-2019 дата публикации

NEUROMODULATION FOR METABOLIC CONDITIONS OR SYNDROMES

Номер: US20190069942A1
Автор: Azamian Bobak Robert, Coe Jonathan Allen, Vafai Scott Bradley
Принадлежит:

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery. 1. (canceled)2. (canceled)3. A method of facilitating hepatic neuromodulation using a laparoscopic approach , the method comprising:laparoscopically delivering a radiofrequency energy delivery device within a subject;positioning a distal portion of the radiofrequency energy delivery device at a location adjacent a portion of a common hepatic artery,wherein the distal portion of the radiofrequency energy delivery device comprises at least one electrode; andcausing radiofrequency energy to be applied by the at least one electrode to one or more nerves of the hepatic plexus sufficient to ablate the one or more nerves in a manner that facilitates a reduction in at least one of a blood glucose level or a lipoprotein level in the subject; andremoving the radiofrequency energy delivery device from the subject.4. The method of claim 3 ,wherein the radiofrequency energy is in a range of 50 kHz to 5 MHz,wherein the radiofrequency energy heats the one or more nerves to a temperature of up to 90 degrees Celsius; andwherein the one or more nerves are sympathetic nerves of the hepatic plexus.5. The method of claim 3 , further comprising confirming ablation of the one or more nerves.6. The method of claim 3 , further comprising maintaining contact between the at least one electrode and the portion of common hepatic artery at a contact pressure of between 0.1 g/mmand 10 g/mm.7. A method of facilitating hepatic neuromodulation using a laparoscopic approach claim 3 , the method comprising:laparoscopically ...

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Номер записи: 70
16-03-2017 дата публикации

Surgical system for connecting body tissue

Номер: US20170071666A1
Автор: Anton Keller, Christoph Rothweiler, Dieter Weisshaupt
Принадлежит: Aesculap AG

A surgical system for connecting body tissue is provided. The surgical system includes a surgical instrument having two tool elements movable relative to each other, each of which comprises a high-frequency electrode. The high-frequency electrodes, in an approach position of the tool elements, define a minimum distance from each other, lying opposite each other and facing each other. The instrument has a shaft at the distal end of which at least a first one of the tool elements is arranged or formed. A second tool element is movable from an operating position, in which it is adapted for movement into the approach position, into a removal position and/or vice versa. A surface area of a perpendicular projection of the second tool element onto a projection plane extending perpendicularly to a shaft direction in a region of the second tool element is smaller in the removal position than in the operating position.

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Номер записи: 71
05-03-2020 дата публикации

Ablation catheters

Номер: US20200069364A1
Автор: Amr Salahieh, Brian D. Brandt, Emma LEPAK, John P. Claude, Jonah Lepak, Tom Saul
Принадлежит: Individual

Cardiac tissue ablation catheters including an inflatable and flexible toroidal or spherically shaped balloon disposed at a distal region of an elongate member, a flexible circuit carried by an outer surface of the balloon, the flexible circuit including, a plurality of flexible branches conforming to the radially outer surface of the balloon, each of the plurality of flexible branches including a substrate, a conductive trace carried by the substrate, and an ablation electrode carried by the substrate, the ablation electrode in electrical communication with the conductive trace, and an elongate shaft comprising a guidewire lumen extending in the elongate member and extending from a proximal region of the inflatable balloon to distal region of the inflatable balloon and being disposed within the inflatable balloon, wherein a distal region of the elongate shaft is secured directly or indirectly to the distal region of the inflatable balloon.

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Номер записи: 72
18-03-2021 дата публикации

CATHETER WITH THIN-FILM ELECTRODES ON EXPANDABLE MEMBRANE

Номер: US20210077184A1
Автор: BASU Shubhayu, Fuentes-Ortega Cesar, Tobey Dustin R., Van Niekerk Pieter E.
Принадлежит:

An apparatus includes a catheter and an end effector. The end effector includes an expandable body and a plurality of electrodes deposited on the outer surface of the expandable body. The expandable body is configured to transition between a non-expanded state and an expanded state. The expandable body has an inner surface and an outer surface. The expandable body defines a plurality of openings extending from the inner surface to the outer surface. The electrodes are configured to expand with the expandable body from the non-expanded state to the expanded state. The electrodes including one or more electrodes selected from the group consisting of mapping electrodes that are configured to sense electrical potentials in tissue contacting the mapping electrodes and ablation electrodes that are operable to ablate tissue contacting the ablation electrodes. 1. An apparatus comprising:(a) a catheter, at least a portion of the catheter being sized and configured to fit within a lumen of a cardiovascular system; and (i) an expandable body, the expandable body being configured to transition between a non-expanded state and an expanded state, the expandable body having an inner surface and an outer surface, the expandable body defining a plurality of openings extending from the inner surface to the outer surface, and', (A) mapping electrodes that are configured to sense electrical potentials in tissue contacting the mapping electrodes, and', '(B) ablation electrodes that are operable to ablate tissue contacting the ablation electrodes., '(ii) a plurality of electrodes deposited on the outer surface of the expandable body, the electrodes being configured to expand with the expandable body from the non-expanded state to the expanded state, the electrodes including one or more electrodes selected from the group consisting of], '(b) an end effector positioned at a distal end of the catheter, the end effector comprising2. The apparatus of claim 1 , the expandable body comprising a ...

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Номер записи: 73
19-03-2015 дата публикации

Electrosurgical (rf) medical instruments for cutting and coagulating tissue

Номер: US20150080891A1
Автор: Barry C. Worrell, Chester O. Baxter, III, David C. Yates, Frederick E. Shelton, IV, Geoffrey S. Strobl, Jennifer M. Mallow, John V. Hunt, Kevin L. Houser, Taylor W. Aronhalt
Принадлежит: Ethicon Endo Surgery Inc

An electrosurgical device is disclosed. The electrosurgical device includes a handle, a shaft extending distally from the handle, and an end effector coupled to a distal end of the shaft. The end effector comprises a first electrode and a second electrode. The second electrode includes a first position and a second position. The second electrode is configured to move from the first position to the second position when a force is applied to the end effector by a tissue section. The first electrode and the second electrode define a treatment area when the second electrode is in the second position.

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Номер записи: 74
05-06-2014 дата публикации

Methods and apparatus for introducing tumescent fluid to body tissue

Номер: US20140155879A1
Автор: Anna Grace Prestezog, Brady D. Esch, Halil Ibrahim Karabey, Jeff Zalewski, Michael S. Mirizzi, Robert Gordon Mcrae, Todd Schoenberger
Принадлежит: COVIDIEN LP

A catheter is usable to treat a hollow anatomical structure (HAS). The catheter comprises one or more shafts which extend away from a proximal end of the catheter toward a distal end thereof. The catheter further comprises an HAS constriction energy source located at or near the distal end of the catheter. The catheter further comprises at least one radially expandable transmural fluid delivery channel located in the catheter near the HAS constriction energy source.

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Номер записи: 75
14-03-2019 дата публикации

Ablation catheter having a shape memory stylet

Номер: US20190076179A1
Автор: Alexei Babkin, David Cabrita, Faysal S. Ahmed, Meital Mazor, Pedram Nourian
Принадлежит: Adagio Medical Inc

An ablation apparatus for creating a lesion in target tissue, the ablation apparatus having an ablation shaft including a handle, a first portion, an ablation portion, distal tip, at least one ablation energy delivery lumen, at least one ablation energy return lumen, and a stylet lumen that extends substantially along a length of the ablation shaft from the handle to at least the ablation portion. The ablation apparatus also includes a stylet that is capable of being inserted into the stylet lumen where the stylet is made of a shape-memory material.

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Номер записи: 76
14-03-2019 дата публикации

CATHETER SENSING AND IRRIGATING

Номер: US20190076190A1
Автор: Bond Jonathan Matthew, Collier Ian Matthew, Harlev Doron, Wallace Andrew Miles
Принадлежит:

Ablation systems of the present disclosure facilitate the safe formation of wide and deep lesions. For example, ablation systems of the present disclosure can allow for the flow of irrigation fluid and blood through an expandable ablation electrode, resulting in efficient and effective cooling of the ablation electrode as the ablation electrode delivers energy at a treatment site of the patient. Additionally, or alternatively, ablation systems of the present disclosure can include a deformable ablation electrode and a plurality of sensors that, in cooperation, sense the deformation of the ablation electrode, to provide a robust indication of the extent and direction of contact between the ablation electrode and tissue at a treatment site. 123-. (canceled)24. A catheter , comprising:an elongated shaft having a proximal end region and a distal end region;an irrigation element at the distal end region of the elongated shaft and positioned to direct irrigation fluid away from the distal end region of the elongated shaft; andan electrical energy delivery electrode at the distal end region of the elongated shaft and enveloping the irrigation element, the electrical energy delivery electrode comprises multiple struts that define a plurality of bounded cells,', 'the struts are configured to conduct and deliver electrical energy along a majority of their length,', 'the struts are movable relative to one another, and', 'at least a portion of the struts are in electrical communication with one another to form a single electrical conductor., 'wherein—'}25. The catheter of wherein the electrical energy delivery electrode comprises a braid.26. The catheter of wherein the electrical energy delivery electrode comprises a mesh.27. The catheter of wherein the struts are coupled to one another at joints.28. The catheter of wherein the struts are moveable relative to one another such that a radial dimension of the electrical energy delivery electrode increases as the struts move ...

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Номер записи: 77
22-03-2018 дата публикации

SYSTEMS AND METHODS FOR SELECTING, ACTIVATING, OR SELECTING AND ACTIVATING TRANSDUCERS

Номер: US20180078218A1
Автор: Moisa Saar, WEBER Michael Hermann
Принадлежит:

A graphical representation may be displayed including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device. A set of user input may be received including an instruction set to reposition a first transducer graphical element in a state in which the first transducer graphical element is located at a first location in the graphical representation and a second transducer graphical element is located at a second location in the graphical representation, the second location closer to a predetermined location in the graphical representation than the first location. In response to conclusion of receipt of the set of user input, the first transducer graphical element may be repositioned from the first location in the graphical representation to the predetermined location in the graphical representation. 1. A system comprising:a data processing device system;an input-output device system communicatively connected to the data processing device system; anda memory device system communicatively connected to the data processing device system and storing a program executable by the data processing device system, the program comprising:display instructions configured to cause the input-output device system to display a graphical representation including at least a plurality of transducer graphical elements, each transducer graphical element of the plurality of transducer graphical elements representative of a respective transducer of a plurality of transducers of a transducer-based device, the graphical representation including a first spatial relationship between the plurality of transducer graphical elements that is consistent with a second spatial relationship between the plurality of transducers of the transducer-based device;input-processing instructions configured to cause reception of a set ...

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Номер записи: 78
23-03-2017 дата публикации

Systems and methods for reduction of atrial fibrillation

Номер: US20170079714A1
Автор: Clark C. Davis, Daryl R. Edmiston, Richard J. Linder, Scott D. Miles
Принадлежит: Coherex Medical Inc

Embodiments of the present invention are directed to ablation catheter systems configured, for example, to ablate tissue adjacent an ostium of the pulmonary vein in a left atria of a heart. In one embodiment, an ablation catheter system includes a handle and a catheter coupled to the handle defining a lumen extending through a length of the catheter, the catheter including a distal end thereof. The ablation catheter system may also include an electrode coupled to the handle with lines extending through the lumen of the catheter, the electrode being configured to be constrained adjacent the distal end of the catheter and configured to be deployed from the distal end of the catheter to an expanded configuration.

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Номер записи: 79
31-03-2022 дата публикации

Catheter apparatuses for modulation of nerves in communication with the pulmonary system and associated systems and methods

Номер: US20220096153A1
Автор: Martin Rothman, Paul Coates
Принадлежит: Medtronic Ardian Luxembourg SARL

Devices, systems, and methods for the selective positioning of an intravascular neuromodulation device are disclosed herein. Such systems can include, for example, an elongated shaft and a therapeutic assembly carried by a distal portion of the elongated shaft. The therapeutic assembly is configured for delivery within a blood vessel. The therapeutic assembly can include a pre-formed shape and can be transformable between a substantially straight delivery configuration; and a treatment configuration having the pre-formed helical shape to position the therapeutic assembly in stable contact with a wall of the body vessel. The therapeutic assembly can also include a mechanical decoupler operably connected to the therapeutic assembly that is configured to absorb at least a portion of a force exerted on the therapeutic assembly by the shaft so that the therapeutic assembly maintains a generally stationary position relative to the target site.

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Номер записи: 80
21-03-2019 дата публикации

SYSTEMS AND METHODS FOR DELIVERY OF A THERAPEUTIC AGENT

Номер: US20190083768A1
Автор: DEEM Mark E., GIFFORD, III Hanson S.
Принадлежит:

Methods and apparatus are provided for applying an fragment of a neurotoxin such as the active light chain (LC) of the botulinum toxin (BoNT), such as one of the serotype A, B, C, D, E, F or G botulinum toxins, via permeabilization of targeted cell membranes to enable translocation of the botulinum neurotoxin light chain (BoNT-LC) molecule across the targeted cell membrane to the cell cytosol where a therapeutic response is produced in a mammalian system. The methods and apparatus include use of catheter based delivery systems, non-invasive delivery systems, and transdermal delivery systems. 120-. (canceled)21. A device for altering function of a bronchial airway of a patient by controlling mucus secretion , the device comprising:a main catheter body configured to extend though a trachea into the bronchial airway; andat least one energy applicator having at least one energy emitter configured to emit energy relative to the main catheter body,wherein the device is adapted to deliver energy from the at least one energy emitter to produce an energy field concentrated in a target region in a wall of the bronchial airway in a first lateral direction from the catheter body to alter cells within the target region.22. The device of claim 21 , wherein the energy is at least one of x-ray energy claim 21 , radiofrequency energy claim 21 , DC current claim 21 , AC current claim 21 , microwave energy claim 21 , and ultrasound energy.23. The device of claim 21 , wherein the at least one energy emitter comprises at least one electrode claim 21 , and the energy is RF energy.24. The device of claim 21 , wherein the at least one energy emitter comprises at least one ultrasound transducer claim 21 , and the energy is ultrasound energy.25. The device of claim 21 , wherein the device is adapted to electroporate cells within the target region.26. The device of claim 25 , wherein the device is further configured to deliver a neurotoxin to the electroporated cells in the target region.27. ...

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Номер записи: 81
02-04-2015 дата публикации

Graphical user interface for association with an electrode structure deployed in contact with a tissue region

Номер: US20150094710A1
Автор: David S. Utley, Jay Qin, John W. Gaiser, Peter H. Muller, Scott H. West, Stuart D. Edwards
Принадлежит: Mederi Therapeutics Inc

Systems and methods deploy an electrode structure in contact with the tissue region. The electrode structure carries a sensor at a known location on the electrode structure to monitor an operating condition. The systems and methods provide an interface, which generate an idealized image of the electrode structure and an indicator image to represent the monitored operating condition in a spatial position on the idealized image corresponding to the location of the sensor on the electrode structure. The interface displays a view image comprising the idealized image and indicator image. The systems and methods cause the electrode structure to apply energy to heat the tissue region while the view image is displayed on the display screen.

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Номер записи: 82
07-04-2016 дата публикации

An ablation catheter

Номер: US20160095650A1
Автор: David Ogle, Roman GREIFENEDER, Tyler McKinley MORTIMER
Принадлежит: CATHRX LTD

An ablation catheter includes a control handle and a catheter sheath removably connectable to the control handle, the catheter sheath defining a fluid lumen and having a plurality of perforations proximal the distal end of the catheter sheath. The ablation catheter further includes a shape-imparting element inserted into the fluid lumen of the catheter sheath and removably connectable to the control handle. The shape-imparting element is connectable to an RF energy source so that, in use, the shape-imparting elements act as an electrode charging fluid into the fluid lumen to be expelled through the plurality of perforations on the catheter sheath.

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Номер записи: 83
07-04-2016 дата публикации

Catheter Apparatuses, Systems, and Methods for Renal Neuromodulation

Номер: US20160095654A1
Автор: Clark Benjamin J., Leung Mark S., Michlitsch Kenneth J., Thai Erik, Wu Andrew, Zarins Denise
Принадлежит:

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver an energy delivery element to a renal artery via an intravascular path. Thermal or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers. 144-. (canceled)45. A method , comprising:introducing a neuromodulation assembly at a distal portion of a treatment device proximate to neural fibers innervating penile tissue of a human patient diagnosed with erectile dysfunction or premature ejaculation;at least partially disrupting function of the neural fibers innervating the penile tissue by applying thermal energy to the neural fibers via the neuromodulation assembly; andremoving the neuromodulation assembly from the patient after treatment,wherein at least partial disruption of the function of the neural fibers innervating the penile tissue therapeutically treats the diagnosed erectile dysfunction or premature ejaculation.46. The method of wherein the neuromodulation assembly is introduced percutaneously.47. The method of wherein the patient is diagnosed with premature ejaculation claim 45 , and wherein at least partial disruption of the function of the neural fibers decreases a frequency of premature ejaculation in the patient.48. The method of wherein the patient is diagnosed with erectile dysfunction claim 45 , and wherein at least partial disruption of the function of the neural fibers increases a frequency of penile erections in the patient.49. A method for treating erectile ...

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Номер записи: 84
05-04-2018 дата публикации

EXPANDABLE INTRA-VENOUS CATHETER FOR A FASTER INTRA-VENOUS FLUID CHALLENGE

Номер: US20180093072A1
Автор: McNeese Marc A., McNeese Shandra Y.
Принадлежит:

An expandable intra-venous catheter for a faster intra-venous fluid challenge combination has a needle with a tip and an opposite base, a block receiving the needle axially, an inflator port in the block and an opposite IV port in the block, the IV port has fluid communication into the needle, at least three inflators deployed along the needle outwardly from the block, the inflator port has gaseous communication into the inflators, a sheath extending from the block over the inflators towards the tip, and an IV tube upon the needle and within the sheath. The present invention has a flat state and an expanded state. 1. A medical device comprising:a hollow needle with a tip and an opposite base;a block receiving said needle axially therein, an inflator port in said block and an opposite intra-venous port in said block;at least three inflators along said needle outwardly from said block towards said tip;said intra-venous port having fluid communication into said needle and said inflator port having gaseous communication into said inflators;a sheath extending from said block over said inflators towards said tip; and,an intra-venous tube concentric and coaxial upon said needle and within said sheath;wherein said device transitions from a flat state having said inflators flat and adjacent to said intra-venous tube to an expanded state having said inflators enlarged radially outwardly from said intra-venous tube.2. The medical device of further comprising:said block having a generally cylindrical form, a diameter, and a length perpendicular to the diameter, a shoulder having a diameter lesser than that of said block and a length lesser than that of said block, said shoulder being coaxial with said block, said shoulder locating opposite said inflator port and said intra-venous port, and said shoulder having fluid communication to said needle; and,said sheath having a conical portion fitting upon said shoulder.3. The medical device of further comprising:said sheath extending ...

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Номер записи: 85
28-03-2019 дата публикации

METHODS AND SYSTEMS FOR ENDOMETRIAL ABLATION UTILIZING RADIO FREQUENCY

Номер: US20190090941A1
Автор: Hundertmark Ronald, Toth Akos
Принадлежит: Minerva Surgical, Inc.

Methods, systems and devices for endometrial ablation. In accordance with a method, a working end of an RF ablation device is positioned in a patient uterus to contact endometrial tissue, the working end comprising a dielectric wall capable of non-expanded and expanded shapes. An indicator mechanism is operatively coupled to the wall and configured to indicate non-expanded and expanded shapes of the wall. 1. (canceled)2. An electrosurgical system for treating uterine tissue , comprising:a handle;a uterine treatment member;an expandable frame configured to deploy the uterine treatment member between non-expanded and expanded shapes;a translatable sleeve coupled between the handle and the frame for actuating the expandable frame to move the treatment member between the non-expanded and expanded shapes;an indicator mechanism on the handle coupled to the translatable sleeve and configured to visually indicate an extent of opening of the treatment member between the non-expanded and expanded shapes.3. The system of claim 2 , wherein the treatment member is configured to couple to an energy delivery controller for delivering ablative energy to uterine tissue claim 2 , and wherein the indicator mechanism generates an electrical signal which is delivered to the energy delivery controller to prevent the energy delivery controller from delivering RF current to the uterine tissue if the treatment member is not opened to a threshold expansion.4. The system of claim 2 , wherein the indicator mechanism comprises a sliding element coupled to axially translate in a slot in the handle.5. The system of claim 4 , wherein the sliding element has a first zone with a first color and a second zone with a second color different than the first color.6. The system of claim 5 , wherein the sliding element travels in a slot in the handle and the handle has a fixed indicator element claim 5 , wherein the fixed indicator element moves from the first zone with the first color to the second zone ...

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Номер записи: 86
28-03-2019 дата публикации

Methods and Apparatus for Monopolar Renal Neuromodulation

Номер: US20190090944A1
Автор: Denise Zarins, Hanson Gifford, III, Howard R. Levin, Mark Deem, Mark Gelfand, Nicolas Zadno
Принадлежит: Medtronic Ardian Luxembourg SARL

Methods and apparatus are provided for monopolar neuromodulation, e.g., via a pulsed electric field. Such monopolar neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, monopolar neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such monopolar neuromodulation is performed bilaterally.

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Номер записи: 87
28-03-2019 дата публикации

Device and Method for Treating Cardiac Disorders by Modulating Autonomic Response

Номер: US20190090946A1
Автор: Asirvatham Samuel J., Knudson Mark B.
Принадлежит: Mayo Foundation for Medical Education and Research

A method and device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia includes a treatment source arranged to supply a treatment medium, a catheter having an end sized for insertion into the pericardial space, a medium delivery assembly having a distal end arranged to be positioned by the catheter into the pericardium, with the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space. A connector operatively couples the delivery tip of the medium delivery assembly to the treatment source, and the delivery tip of the medium delivery assembly including a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space. The device performs modulation or ablation of the autonomic nervous system at selected treatment areas within the pericardium. 1. (canceled)2. A device for modulating the autonomic nervous system adjacent a pericardial space to treat cardiac arrhythmia , the device comprising:a treatment source arranged to supply a treatment medium;a catheter having a proximal end and a distal end, the distal end sized for insertion into the pericardial space;a medium delivery assembly, the medium delivery assembly having a proximal end and a distal end, the distal end of the medium delivery assembly arranged to be positioned by the distal end of the catheter, the distal end of the delivery assembly comprising a delivery tip arranged to extend away from the distal end of the catheter into the pericardial space; anda connector operatively coupling the delivery tip of the medium delivery assembly to the treatment source,wherein the delivery tip of the medium delivery assembly includes a plurality of delivery points for delivering the treatment medium at a plurality of treatment areas within the pericardial space.3. The device of claim 2 , wherein the delivery tip of the ...

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Номер записи: 88
09-04-2015 дата публикации

Blood flow rate measurement device

Номер: US20150099989A1
Автор: Risato KOBAYASHI
Принадлежит: Terumo Corp

A blood flow rate acquisition device which does not require an injection operation for injecting a cooling saline into a blood vessel and can acquire a blood flow rate inside the blood vessel includes an elongated member that is insertable into a blood vessel, a flow velocity measuring member that is disposed in a distal end of a distal end portion of the elongated member in order to measure a flow velocity of blood flow, a cross-sectional area measuring member that is disposed on a side surface in the distal end portion of the elongated member in order to measure a cross-sectional area of a lumen of the blood vessel, and an acquisition device that acquires the blood flow rate by using detection values detected by the flow velocity measuring member and the cross-sectional area measuring member.

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Номер записи: 89
13-04-2017 дата публикации

Self-centering multiray ablation catheter

Номер: US20170100189A1
Автор: Jeffrey Clark, Jeffrey Schultz, John Ashton, Ryan Hoitink
Принадлежит: Biosense Webster Israel Ltd

A catheter for ablating tissue is disclosed that has a self-centering multiray electrode assembly. The self-centering multiray electrode assembly may have a plurality of spines, each of which a preshaped, expanded configuration that curves to change an orientation of the spine from being directed towards the distal end of catheter body to being directed towards the proximal end of the catheter body. The ablation electrodes engage ostial tissue when a maximal outer diameter of the self-centering multiray electrode assembly is engaged with an inner diameter of a vessel. The compliance of each spine may vary along its length. When the self-centering multiray electrode assembly is engaged within a vessel, the ablation electrodes are brought into contact with tissue and may be used to form lesions in a circumferential path around the vessel.

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Номер записи: 90
23-04-2015 дата публикации

Immune system neuromodulation and associated systems and methods

Номер: US20150111918A1
Автор: Neil Barman, Paul Sobotka
Принадлежит: Medtronic Ardian Luxembourg S.a.r.l

Methods for treating a patient using therapeutic immune system neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to methods including modulating nerves proximate a vessel or duct of an immune system organ using an intravascularly or intraluminally positioned therapeutic element. One or more measurable physiological parameters corresponding to an immune system disorder, a condition associated with sympathetic activity in an immune system organ, or a condition associated with central sympathetic activity in the patient can thereby be reduced.

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Номер записи: 91
23-04-2015 дата публикации

Modulation of nerves innervating the liver

Номер: US20150112332A1
Автор: Bobak Robert Azamian, Jonathan Allen Coe, Scott Bradley Vafai
Принадлежит: Metavention Inc

According to some embodiments, a method of treating a subject having diabetes or symptoms associated with diabetes is provided. The method includes delivering a neuromodulation catheter within a vessel (e.g., hepatic artery) having surrounding nerves that innervate the liver (e.g., sympathetic nerves of the hepatic plexus). The method may also include modulating (e.g., disrupting, ablating, stimulating) the nerves by mechanical compression, energy delivery, or fluid delivery.

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Номер записи: 92
03-07-2014 дата публикации

Systems and methods for reduction of atrial fibrillation

Номер: US20140188098A1
Автор: Clark C. Davis, Daryl R. Edmiston, Richard J. Linder, Scott D. Miles
Принадлежит: Coherex Medical Inc

Embodiments of the present invention are directed to ablation catheter systems configured, for example, to ablate tissue adjacent an ostium of the pulmonary vein in a left atria of a heart. In one embodiment, an ablation catheter system includes a handle and a catheter coupled to the handle defining a lumen extending through a length of the catheter, the catheter including a distal end thereof. The ablation catheter system may also include an electrode coupled to the handle with lines extending through the lumen of the catheter, the electrode being configured to be constrained adjacent the distal end of the catheter and configured to be deployed from the distal end of the catheter to an expanded configuration.

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Номер записи: 93
11-04-2019 дата публикации

SYSTEMS, ASSEMBLIES, AND METHODS FOR TREATING A BRONCHIAL TREE

Номер: US20190105102A1
Автор: Dimmer Steven C., Mayse Martin L.
Принадлежит:

Systems, assemblies, and methods to treat pulmonary diseases are used to decrease nervous system input to distal regions of the bronchial tree within the lungs. Treatment systems damage nerve tissue to temporarily or permanently decrease nervous system input. The treatment systems are capable of heating nerve tissue, cooling the nerve tissue, delivering a flowable substance that cause trauma to the nerve tissue, puncturing the nerve tissue, tearing the nerve tissue, cutting the nerve tissue, applying pressure to the nerve tissue, applying ultrasound to the nerve tissue, applying ionizing radiation to the nerve tissue, disrupting cell membranes of nerve tissue with electrical energy, or delivering long acting nerve blocking chemicals to the nerve tissue. 1. A method of treating at least partial obstruction of an airway caused by excessive intraluminal mucus , mucous glands hypertrophy , or both , the method comprising:damaging nerve tissue at a first location along the airway so as to attenuate transmission of signals to and/or from mucous producing cells at a second location along the airway so as to reduce a production of mucous from the mucous producing cells.2. The method of claim 1 , wherein damaging nerve tissue comprises damaging efferent nerve tissue to inhibit signals from being transmitted from the brain to airway to mucous producing cells.3. The method of claim 1 , wherein damaging nerve tissue disrupts a baseline level of mucous secretion.4. The method of claim 1 , wherein damaging nerve tissue attentuates transmission of signals traveling along vagus nerves that cause mucus production.5. The method of claim 1 , wherein attenuation of the transmission of signals comprises hindering claim 1 , limiting claim 1 , blocking claim 1 , and/or interrupting transmission of signals.6. The method of claim 1 , wherein attenuation of the transmission of signals comprises decreasing signal amplitude claim 1 , weakening transmission of signals claim 1 , or both.7. The ...

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Номер записи: 94
30-04-2015 дата публикации

INTRAVASCULAR CATHETER WITH PERI-VASCULAR NERVE ACTIVITY SENSORS

Номер: US20150119674A1
Автор: Almany Steven, FISCHELL DAVID R., FISCHELL TIM A., Ghazarossian Vartan
Принадлежит: ABLATIVE SOLUTIONS, INC.

An intravascular catheter for peri-vascular nerve activity sensing or measurement includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The system also may include means to limit and/or adjust the depth of penetration of the needles. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. The addition of an injection lumen at the proximal end of the catheter and openings in the needles adds the functionality of ablative fluid injection into the perivascular space for an integrated nerve sending and ablation capability. 1. A catheter for sensing the activity of nerves outside of the interior wall of a target vessel of a human body comprising:a catheter body having a central axis extending in a longitudinal direction and also having a central lumen;at least two needle guiding elements adapted to expand outwardly toward the interior wall of the target vessel;at least two needles, each needle having a distal electrode, the at least two needles adapted to be advanced outwardly, guided by the at least two needle guiding elements to penetrate the interior wall of the target vessel and advance further into the tissue outside of the inside wall of the target vessel;at least two wires for conducting signals sensed by the at least two electrodes, the wires connecting the electrodes to external equipment outside of the catheter.2. The catheter of where each needle guiding element is a guide tube having a lumen.3. The catheter of where each needle is advanced outwardly coaxially through ...

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Номер записи: 95
30-04-2015 дата публикации

METHOD AND APPARATUS FOR SPARING PAIN CONDUCTING NERVES DURING RENAL DENERVATION

Номер: US20150119875A1
Автор: Almany Steven, FISCHELL DAVID R., FISCHELL TIM A., Ghazarossian Vartan
Принадлежит: ABLATIVE SOLUTIONS, INC.

An intravascular catheter for peri-vascular nerve activity ablation and/or sensing includes multiple needles advanced through supported guide tubes (needle guiding elements) which expand with open ends around a central axis to contact the interior surface of the wall of the renal artery or other vessel of a human body allowing the needles to be advanced though the vessel wall into the perivascular space. The catheter also includes structures which provide radial and lateral support to the guide tubes so that the guide tubes open uniformly and maintain their position against the interior surface of the vessel wall as the sharpened needles are advanced to penetrate into the vessel wall. Ablative energy or fluid is delivered from the needles in or near the adventitia to ablate nerves outside of the media while sparing nerves within the media. 1. A catheter for ablating the nerves outside of the media of a target vessel of a human body comprising:a catheter body having a central axis extending in a longitudinal direction;at least two needle guiding elements adapted to expand outwardly toward the interior wall of the target vessel;at least two needles, each needle having a distal electrode, the at least two needles adapted to be advanced outwardly, guided by the at least two needle guiding elements to penetrate the interior wall of the target vessel and advance further into the tissue outside of the inside wall of the target vessel;at least two wires for conducting electrical current to the at least two electrodes, the wires connecting the electrodes to external equipment outside of the catheter.2. The catheter of where each needle guiding element is a guide tube having a lumen.3. The catheter of where each needle is advanced outwardly coaxially through the lumen of a guide tube.4. The catheter of further including at least three needle guiding elements claim 1 , three needles claim 1 , and three insulated wires.5. The catheter of where the needle guiding elements have a ...

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Номер записи: 96
30-04-2015 дата публикации

Embedded thermocouple in denervation flex circuit

Номер: US20150119882A1
Автор: Hong Cao, Kenneth R. Larson
Принадлежит: Boston Scientific Scimed Inc

A medical device for sympathetic nerve ablation may include a catheter shaft, an expandable member disposed on or coupled to the catheter shaft, and a plurality of elongate electrode assemblies each constructed as a flexible circuit having a plurality of layers. The expandable member may be configured to shift between an unexpanded configuration and an expanded configuration. The plurality of electrode assemblies may be disposed on an outer surface of the expandable member. Each of the plurality of electrode assemblies may include a temperature sensor within the plurality of layers.

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Номер записи: 97
13-05-2021 дата публикации

ELECTROPORATION SYSTEM AND METHOD OF ENERGIZING A CATHETER

Номер: US20210137587A1
Автор: Olson Eric
Принадлежит:

The present disclosure provides electroporation systems and methods of energizing a catheter for delivering electroporation. A catheter for delivering electroporation includes a distal section and an electrode assembly. The distal section is configured to be positioned in a vein within a body. The vein defines a central axis. The electrode assembly is coupled to the distal section and includes a structure and a plurality of electrodes distributed thereabout. The structure is configured to at least partially contact the vein. Each of the electrodes is configured to be selectively energized to form a circumferential ring of energized electrodes that is concentric with the central axis of the vein. 1. A catheter for delivering electroporation , the catheter comprising:a distal section configured to be positioned in a vein within a body, the vein defining a central axis; and a structure configured to at least partially contact the vein, and', 'a plurality of electrodes distributed about the structure, each electrode of the plurality of electrodes configured to be selectively energized to form a circumferential ring of energized electrodes that is concentric with the central axis of the vein., 'an electrode assembly coupled to the distal section, the electrode assembly comprising2. The catheter of claim 1 , wherein the structure comprises a balloon around which the plurality of electrodes are distributed.3. The catheter of claim 1 , wherein the structure comprises a basket having a plurality of splines along which the plurality of electrodes is distributed.4. The catheter of claim 3 , wherein the plurality of splines define first and second poles at which the plurality of splines join claim 3 , and wherein the plurality of electrodes are concentrated away from the first and second poles.5. The catheter of claim 1 , wherein the circumferential ring of energized electrodes is non-circular.6. An electroporation system comprising: a structure configured to at least partially ...

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Номер записи: 98
13-05-2021 дата публикации

Devices and methods for treating a nerve of the nasal cavity using image guidance

Номер: US20210137610A1
Автор: Mojgan SAADAT, Vahid Saadat, William Jason Fox
Принадлежит: Arrinex Inc

The invention disclosed here generally relates to devices used to identify the location of a never in order to modify a property of the nerve. Specifically, the invention utilized pre-operative scans of a patient's nasal cavity in order to identify target treatment locations when a nerve to be treated is located. The image of the nasal cavity and target treatment location can be registered with the real time position of the nasal cavity using a surgical navigation system in order to assist in guiding a surgical probe to the target treatment location.

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Номер записи: 99
03-05-2018 дата публикации

BLADDER TISSUE MODIFICATION FOR OVERACTIVE BLADDER DISORDERS

Номер: US20180116707A1
Автор: Avneri Itzhak, Avneri Shahar, BEN-EZRA Omry
Принадлежит:

Regions of tissue having reduced electrical propagation are created in a bladder to affect its electrical or mechanical properties. To create these tissue regions, a tubular device is advanced through the urethra leading to the interior of the bladder, a distal expandable structure of the device is expanded to contact the inner wall of the bladder, and electrodes or other active energy delivery elements of the device are activated to deliver ablation energy. The electrodes or other active energy delivery elements are disposed over the expandable structure which is shaped to conform to the interior of the bladder. The inner wall of the organ is ablated in a predetermined pattern. The same or other electrodes disposed over the expandable structure can used to electrically map the bladder. This map of electrical activity can be used to create the predetermined pattern. 1. A device for treating a disorder in a hollow bodily organ , the device comprising:a shaft advanceable through a bodily channel of a subject to reach a cavity of the organ;an ablation member having a collapsed configuration for advancement through the bodily channel and an expanded configuration adapted to create a predetermined pattern of electrically isolated tissue regions in an inner wall of the hollow bodily organ, with each electrically isolated tissue region being defined by at least one continuous ablation line and being no larger than half of a total inner surface area of the bodily organ.2. The device of claim 1 , further comprising an expandable member coupled to a distal end of the shaft claim 1 , the expandable member having a collapsed configuration advanceable through the bodily passage to reach the cavity of the organ and an expanded configuration configured to contact an inner wall of the organ when the expandable member is advanced therein.3. The device of claim 2 , wherein the ablation member is disposed over the expandable member.4. The device of claim 2 , wherein the expandable ...

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Номер записи: 100