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Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Применить Всего найдено 9766. Отображено 100.
09-10-2017 дата публикации

Динамический фантом левого желудочка сердца

Номер: RU0000174282U1
Автор: Владимир Николаевич Макаренко, Владимир Сергеевич Березницкий, Михаил Дмитриевич Маргасов
Принадлежит: Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр сердечно-сосудистой хирургии имени А.Н. Бакулева" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦССХ им. А.Н. Бакулева" Минздрава России)

Полезная модель относится к медицинской технике и предназначена для моделирования левого желудочка сердца человека. Динамический фантом левого желудочка сердца включает имитатор левого желудочка сердца, выполненный из эластичного материала, шприц с поршнем, держатель для шприца, привод поршня, редуктор и электродвигатель. Технический результат - повышение воспроизводимости результатов измерений полезной модели в течение всего срока эксплуатации, достигается тем, что привод поршня состоит из штока, один конец которого соединен с поршнем, а другой конец шарнирно связан с шатуном, противоположный конец которого шарнирно закреплен на оси, вставленной в отверстие эксцентрика дискообразной формы, центральная ось вращения которого является выходом редуктора. Шток, шатун, эксцентрик дискообразной формы с осями выполнены из металла. 1 пр., 1 ил. Ц 1 174282 ко РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) (11) сэр а за за (13) х $ х $ ом КО оные М1 (50) МПК ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ СОЗВ 23/28 (2006.01) (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (21)(22) Заявка: 2017123234, 30.06.2017 (24) Дата начала отсчета срока действия патента: 30.06.2017 Дата регистрации: 09.10.2017 Приоритет(ы): (22) Дата подачи заявки: 30.06.2017 (45) Опубликовано: 09.10.2017 Бюл. № 28 Адрес для переписки: 119049, Москва, Ленинский пр-кт, 8, ФГБУ "НМИЦССХ им. А.Н. Бакулева" Минздрава России, отдел интеллектуальной собственности, Юшкевич Т.И. (72) Автор(ы): Макаренко Владимир Николаевич (КО), Маргасов Михаил Дмитриевич (КП), Березницкий Владимир Сергеевич (КП) (73) Патентообладатель(и): Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр сердечно-сосудистой хирургии имени А.Н. Бакулева" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦССХ им. А.Н. Бакулева" Минздрава России) (КП) (56) Список документов, цитированных в отчете о поиске: 0 2016/0133159 А1, 12.05.2016. 05 8535061 В2, 17.09.2013. КО 2311893 С1, 10.12.2007. (54) ДИНАМИЧЕСКИЙ ...

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Номер записи: 1
01-03-2012 дата публикации

Method and System For Patient-Specific Modeling of Blood Flow

Номер: US20120053921A1
Автор: Charles A. Taylor
Принадлежит: HeartFlow Inc

Embodiments include a system for planning treatment for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of the patient, create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, and determine a first fractional flow reserve within the anatomical structure of the patient based on the three-dimensional model and information regarding a physiological condition of the patient. The at least one computer system may be further configured to receive input from a user regarding a plan of treatment, modify the physiological condition of the patient based on the received input, and determine a second fractional flow reserve within the anatomical structure of the patient based on the modified physiological condition of the patient.

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Номер записи: 2
26-07-2012 дата публикации

Image processing device, image processing method and program

Номер: US20120188283A1
Автор: Takeshi Ohashi
Принадлежит: Sony Corp

An image processing device includes: a first feature amount extraction unit configured to extract a first feature amount from an image; a position detection unit configured to detect observation positions from the image based on a position detection dictionary, and the first feature amount extracted from the image; a second feature amount extraction unit configured to extract a second feature amount from the observation position; an observation-order determining unit configured to determine the order of observing the observation positions based on an order generation dictionary, and respective second feature amounts of the observation positions; and an image generation unit configured to generate observation images for displaying the observation positions in the observation order based on the image, the detected observation positions and the determined observation order.

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Номер записи: 3
28-02-2013 дата публикации

Detection of lipid core plaque cap thickness

Номер: US20130053698A1
Автор: Joel S. Raichlen, Sean P. Madden
Принадлежит: Infraredx Inc

Described are methods, systems, and apparatus, including computer program products for examining a blood vessel wall. The blood vessel wall is illuminated with near-infrared light. Reflected near-infrared light from the blood vessel wall is received. A reflectance spectrum based on the reflected near-infrared light from the blood vessel wall is determined. Whether the reflectance spectrum is indicative of a presence of a lipid core plaque (LCP) by applying an LCP classifier to the reflectance spectrum is determined. A thickness of an LCP cap is determined by applying an LCP cap thickness classifier to the reflectance spectrum if the reflectance spectrum is indicative of the presence of the LCP. Indicia of the thickness of the LCP cap are displayed.

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Номер записи: 4
07-03-2013 дата публикации

System and methods for intraoperative guidance feedback

Номер: US20130060146A1
Автор: Adrain Linus Dinesh MARIAMPILLAI, Beau Anthony STANDISH, Michael Ka Kit LEUNG, Victor Xiao Dong Yang
Принадлежит: RYERSON UNIVERSITY

Systems and methods for surgical guidance and image registration are provided, in which three-dimensional image data associated with an object or patient is registered to topological image data obtained using a surface topology imaging device. The surface topology imaging device may be rigidly attached to an optical position measurement system that also tracks fiducial markers on a movable instrument. The instrument may be registered to the topological image data, such that the topological image data and the movable instrument are registered to the three-dimensional image data. The three-dimensional image data may be CT or MRI data associated with a patient. The system may also co-register images pertaining to a surgical plan with the three-dimensional image data. In another aspect, the surface topology imaging device may be configured to directly track fiducial markers on a movable instrument. The fiducial markers may be tracked according to surface texture.

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Номер записи: 5
14-03-2013 дата публикации

Method and system for patient-specific modeling of blood flow

Номер: US20130064438A1
Автор: Charles A. Taylor, Christopher K. Zarins, Gilwoo Choi, Timothy A. Fonte, Ying Bai
Принадлежит: HeartFlow Inc

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

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Номер записи: 6
14-03-2013 дата публикации

Method and system for patient-specific modeling of blood flow

Номер: US20130066618A1
Автор: Charles A. Taylor, Christopher K. Zarins, Gilwoo Choi, Timothy A. Fonte, Ying Bai
Принадлежит: HeartFlow Inc

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

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Номер записи: 7
18-04-2013 дата публикации

System and method for data reconstruction in soft-field tomography

Номер: US20130096425A1
Автор: Kimmo Henrik Uutela, Matti Lassas, Petri Ola, Samuli Siltanen, Ville Kolehmainen
Принадлежит: General Electric Co

A system and method for data reconstruction in soft-field tomography are provided. One method includes selecting a model domain for an EIT data set, determining a minimally anisotropic error in the model domain and correcting the model domain. The method also performing isotropization using the determined minimally anisotropic error to recover a boundary shape and isotropic conductivity for the EIT data set.

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Номер записи: 8
23-05-2013 дата публикации

Method and apparatus for performing dual-modality imaging

Номер: US20130131493A1
Автор: Alexander Ganin, Joan M. Hanson, Kathryn M. Littlejohn, Ling Sun, Scott David Wollenweber, William J. Bridge
Принадлежит: General Electric Co

A method for performing an examination of a patient using a dual-modality imaging system includes accessing a list that includes a magnetic resonance imaging (MRI) examination protocol to be used to perform a predetermined MRI examination, the examination protocol including a plurality of MRI protocol actions, receiving an input selecting at least one of the MRI protocol actions, scanning the patient using the MRI examination protocol, scanning the patient using a positron emission tomography (PET) imaging system to acquire PET data, and marking the PET data, using a first visual indication, to indicate the selected MRI protocol action. An imaging system and a non-transitory computer readable medium are also described herein.

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Номер записи: 9
30-05-2013 дата публикации

Method and system for automatically setting a landmark for brain scans

Номер: US20130136329A1
Автор: Robert David Darrow, Thomas Kwok-Fah Foo, Vivek Prabhakar Vaidya, Xiaodong Tao
Принадлежит: General Electric Co

A method, system and apparatus for automatically setting a landmark for brain scans are described. In one embodiment, a method for medical image processing is described. The method comprises obtaining, by an imaging device, at least one image of a head of a subject. In addition, the method also comprises identifying, by a computer-based system, a reference feature in the at least one image associated with the head. The method also comprises automatically setting, by the computer-based system, a landmark based, at least in part, upon the reference feature.

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Номер записи: 10
22-08-2013 дата публикации

Method for evaluating blush in myocardial tissue

Номер: US20130217985A1
Автор: CHENG Chen, David Mark Henri GOYETTE, Peter DVORSKY, T. Bruce Ferguson, Jr.
Принадлежит: Novadaq Technologies ULC

Vessel perfusion and myocardial blush are determined by analyzing fluorescence signals obtained in a static region-of-interest (ROI) in a collection of fluorescence images of myocardial tissue. The blush value is determined from the total intensity of the intensity values of image elements located within the smallest contiguous range of image intensity values containing a predefined fraction of a total measured image intensity of all image elements within the ROI. Vessel (arterial) peak intensity is determined from image elements located within the ROI that have the smallest contiguous range of highest measured image intensity values and contain a predefined fraction of a total measured image intensity of all image elements within the ROI. Cardiac function can be established by comparing the time differential between the time of peak intensity in a blood vessel and that in a region of neighboring myocardial tissue both pre and post procedure.

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Номер записи: 11
03-10-2013 дата публикации

Method and Apparatus for Indicating the Emergence of an Ulcer

Номер: US20130261495A1
Автор: Adam Geboff, Brian Jude Petersen, David Charles Kale, David Robert LINDERS, Jeffrey Mark ENGLER, Jonathan David Bloom
Принадлежит: PODIMETRICS Inc

A method of monitoring a patient's foot forms a thermogram of the sole of at least one foot of the patient, and determines whether the thermogram presents at least one of a plurality of prescribed patterns. The method also compares the thermogram against a prior thermogram of the same foot, and produces output information indicating the emergence of an ulcer on a given portion on the at least one foot as a function of 1) whether the thermogram is determined to present the at least one pattern, and 2) the comparison with the prior thermogram, which shows non-ulcerated tissue at the given location.

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Номер записи: 12
17-10-2013 дата публикации

System and Method for Improved Intra-Oral Scanning Protocol and Calibration

Номер: US20130273492A1
Автор: Joell Cruz, Zachary B. Suttin, Sr.
Принадлежит: Biomet 3I LLC

A method of providing an accurate three-dimensional scan of a dental arch area is disclosed. The arch area has two segments and a connecting area between the two segments. The connecting area has homogeneous features. A connecting-geometry tool with at least one definable feature is affixed to the arch area. The definable feature overlays at least part of the connecting area. The arch area is scanned to produce a scanned dataset of the arch area. The definable feature of the connecting-geometry tool on the connection area is determined based on the scanned dataset. The dimensions of the arch area are determined based on the data relating to the definable features from the scanned dataset.

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Номер записи: 13
07-11-2013 дата публикации

Method for evaluating a pet dataset in relation to a neurotransmitter and / or neuromodulator

Номер: US20130296688A1
Автор: Bjorn Heismann, Sebastian Schmidt
Принадлежит: SIEMENS AG

A method is disclosed for evaluating a PET dataset with information concerning spatial distribution of a neurotransmitter and/or a neuromodulator in the brain of a patient wherein, in addition to the PET dataset, an especially morphometric magnetic resonance image dataset is recorded, which is or will be registered with the PET dataset. Concentration data of the spatial distribution is assigned to at least one specific region of the brain, especially to a nucleus, taking into account the magnetic resonance image data, for establishing result data assigned to the region.

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Номер записи: 14
14-11-2013 дата публикации

SYSTEM AND METHODS FOR MANAGING BLOOD LOSS OF A PATIENT

Номер: US20130303870A1
Автор: Miller Kevin J., Satish Siddarth, Zandifar Ali
Принадлежит: Gauss Sergical

One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample; extracting a feature from an area of the image corresponding to the physical sample; estimating a blood volume indicator of the physical sample according to the extracted feature; estimating a patient blood loss based on the blood volume indicator; estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss; receiving a measured patient hematocrit; and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit. 1. A method for managing blood loss of a patient , comprising:receiving an image of a physical sample;extracting a feature from an area of the image corresponding to the physical sample;estimating a blood volume indicator of the physical sample according to the extracted feature;estimating a patient blood loss based on the blood volume indicator;estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss;receiving a measured patient hematocrit; andgenerating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit.2. The method of claim 1 , further comprising tracking a quantity of a fluid administered to the patient intravenously and estimating an intracirculatory patient hematocrit based on a previous patient hematocrit claim 1 , the estimated patient blood loss claim 1 , a quantity of a fluid administered to the patient claim 1 , and the estimated patient blood volume.3. The method of claim 2 , further comprising extrapolating a volume of insensible patient fluid loss from a difference between the estimated intracirculatory patient hematocrit and the measured patient hematocrit.4. The method of claim 2 , further comprising estimating an effectiveness of the ...

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Номер записи: 15
14-11-2013 дата публикации

Method and apparatus for processing of stroke ct scans

Номер: US20130303900A1
Автор: Wieslaw Lucjan Nowinski
Принадлежит: Agency for Science Technology and Research Singapore

An automatic technique for stroke identification, localization, quantification and prediction, has the steps of receiving a CT scan, pre-processing it to extract the brain region corresponding to a brain volume of a subject who has suffered a stroke; identifying whether a hemorrhage is present in the brain volume and if so obtaining data characterizing the hemorrhage; otherwise identifying whether an infarct is present and if so obtaining data characterizing it; analyzing the results using a brain atlas; and, using the results of the analysis, obtaining at least one predictive value characterizing a prediction about the subject.

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Номер записи: 16
21-11-2013 дата публикации

Guide wire with position sensing electrodes

Номер: US20130310673A1
Автор: Andres Claudio Altmann, Assaf Govari, Christopher Thomas Beeckler
Принадлежит: Biosense Webster Israel Ltd

An apparatus includes a guide wire configured to be inserted into a passage of a living body, and at least one electrical conductor and electrical insulation covering a surface of the conductor with a gap formed in the electrical insulation at a predefined position on the guide wire. A processor is configured to measure an electrical impedance of the body between the conductor at the gap and one or more electrodes fixed to the body, and to calculate a location of the gap within the passage in the body in response to the measured impedance.

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Номер записи: 17
28-11-2013 дата публикации

DEVICES, SYSTEMS, AND METHODS FOR VIRTUAL STAINING

Номер: US20130317369A1
Автор: Bryant-Greenwood Peter, ROSENBLATT Kevin P., Yu Jeffrey N.
Принадлежит: Genetic Innovations, Inc.

The disclosure herein provides methods, systems, and devices for virtually staining biological tissue for enhanced visualization without use of an actual dye or tag by detecting how each pixel of an unstained tissue image changes in waveform after staining with a certain dye(s) and/or tag(s) or other transformation under a certain electromagnetic radiation source, developing a virtual staining transform based on such detection, and applying such virtual staining transform to an unstained biological tissue to virtually stain the tissue. 1. An apparatus for providing medical therapy to an in vivo tissue sample , the apparatus comprising:a medical probe having a virtual staining device configured to provide in vivo virtual staining of the in vivo tissue sample, the virtual staining device comprising an electromagnetic radiation source for directing an electromagnetic radiation at the tissue sample, and a detector for detecting electromagnetic radiation reflected or transmitted from the tissue sample,a communication interface configured to provide communication between the electromagnetic radiation source and a computer system, or the detector and the computer system;an initial image generation module of the computer system configured to generate an input image from the detected electromagnetic radiation from the tissue sample, wherein the first image comprises a plurality of pixels;a virtual staining module of the computer system configured to assign a virtual stain to the input image of the in vivo tissue sample based on an identified waveform associated with each one of a plurality of pixels forming the input image; anda therapeutic element configured to provide the medical therapy to the tissue sample based at least in part on the virtual stain.2. The apparatus of claim 1 , wherein the therapeutic element is incorporated into the medical probe.366-. (canceled)67. A computer-implemented method for virtually staining a tissue sample claim 1 , the computer-implemented ...

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Номер записи: 18
28-11-2013 дата публикации

ENDOSCOPE APPARATUS

Номер: US20130317371A1
Автор: TAKEI Shunji
Принадлежит:

An endoscope apparatus for generating an image of a target site containing a fluorescent substance, including an image pickup section provided with pixels for generating image pickup signals corresponding to a red color region and a band closer to a long wavelength side than the red color region and pixels for generating an image pickup signal corresponding to a band closer to a short wavelength side than the red color region, a light source section emitting to the target site, excitation light for exciting the fluorescent substance and generating fluorescence and reference light for generating reflected light from the target site, and an image processing unit that acquires an image obtained by separating a signal component generated upon receiving the fluorescence from the image pickup signal generated by the image pickup section and an image obtained by separating a signal component generated upon receiving the reflected light. 1. An endoscope apparatus for generating an image of a site to be observed containing a fluorescent substance that is excited by light in a wavelength band of a red color region and emits fluorescence in a wavelength band which is closer to a long wavelength side than the red color region , comprising:an image pickup section provided with pixels for generating image pickup signals corresponding to the wavelength band of the red color region and the wavelength band which is closer to the long wavelength side than the red color region and pixels for generating an image pickup signal corresponding to a wavelength band closer to a short wavelength side than the wavelength band of the red color region;a light source section configured to emit to the site to be observed, excitation light in the wavelength band of the red color region for exciting the fluorescent substance and generating the fluorescence and reference light in the wavelength band set closer to the short wavelength side than the wavelength band of the red color region for ...

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Номер записи: 19
05-12-2013 дата публикации

DENTAL APPARATUS, MEDICAL APPARATUS AND CALCULATION METHOD

Номер: US20130323673A1
Автор: Hakomori Shiho, Tamamura Koshi
Принадлежит: SONY CORPORATION

There is provided a dental apparatus including a light source for emitting a light to irradiate at least one of a tooth, a gum, a plaque and a calculus of an oral cavity, a light detector for detecting fluorescence from the oral cavity emitted to the light irradiated from the light source, and a control unit for outputting first data for visualizing a temporal change in a fluorescence intensity based on the fluorescence detected by the light detector. Also, there is provided a calculation method including irradiating an excited light, detecting a fluorescence intensity, and calculating a temporal change in the fluorescence intensity in a depth direction. 1. A dental apparatus , comprising:a light source for emitting a light to irradiate at least one of a tooth, a gum, a plaque and a calculus of an oral cavity;a light detector for detecting fluorescence from the oral cavity emitted to the light irradiated from the light source; anda control unit for outputting first data for visualizing a temporal change in a fluorescence intensity based on the fluorescence detected by the light detector.2. The dental apparatus according to claim 1 , whereina photosensitizer that is excited by irradiating the light is distributed in a depth direction of the gum such that the photosensitizer is bonded to or incorporated into periodontitis bacteria, andthe control unit outputs the first data based on a fluorescence intensity distribution in the depth direction of the gum from the photosensitizer emitted to the light irradiation.3. The dental apparatus according to claim 2 , whereinthe control unit calculates a temporal change in the fluorescence intensity in the depth direction based on a calculated temporal change in the distribution of the photosensitizer in a ground state in the depth direction, a calculated temporal change in an intensity distribution of the light in the depth direction, and a fluorescence intensity on a surface of the gum detected by the light detector.4. The ...

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Номер записи: 20
05-12-2013 дата публикации

DENTAL APPARATUS, IMAGE ACQUISITION METHOD, AND INFORMATION PROCESSING APPARATUS

Номер: US20130323674A1
Автор: Hakomori Shiho, Tamamura Koshi
Принадлежит: SONY CORPORATION

A dental apparatus includes a light irradiation unit for emitting a light to irradiate an oral cavity, an image capturing unit for image-capturing the oral cavity light irradiated by the light irradiation unit, and an output unit for outputting data for highlighting and displaying at least one of a plaque site and a calculus site on an image of the oral cavity based on an image captured result by the image capturing unit. 1. A dental apparatus , comprising:a light irradiation unit for emitting a light to irradiate an oral cavity;an image capturing unit for image-capturing the oral cavity light irradiated by the light irradiation unit; andan output unit for outputting data for highlighting and displaying at least one of a plaque site and a calculus site on an image of the oral cavity based on an image captured result by the image capturing unit.2. The dental apparatus according to claim 1 , whereina light source emits a near-infrared light, andthe output unit outputs the data for highlighting and displaying at least one of the plaque site and the calculus site on the image of the oral cavity based on a reflected light amount from the oral cavity emitted to the near-infrared rays irradiated by the light irradiation unit.3. The dental apparatus according to claim 2 , whereinthe output unit outputs the data for highlighting and displaying being capable of discerning the plaque site and the calculus site on the image of the oral cavity based on the reflected light amount from the oral cavity emitted to the near-infrared rays irradiated by the light irradiation unit.4. The dental apparatus according to claim 1 , whereinthe light irradiation unit emits p-polarized light, andthe output unit outputs the data for highlighting and displaying the calculus site on the image of the oral cavity based on an s-polarized light amount of a returned light from the oral cavity emitted to the p-polarized light irradiated by the light irradiation unit.5. The dental apparatus according to ...

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Номер записи: 21
12-12-2013 дата публикации

Multi-spectral imaging system and method for remote biometric measurement of human physiological parameters

Номер: US20130331669A1
Автор: John A. Kogut, Marc Berte
Принадлежит: Raytheon Co

Some embodiments relate to a method of collecting light reflected from a subject and analyzing the light to monitor time-varying physiological parameters of the subject. Other embodiments relate to a system including collection optics to receive light reflected from a subject, filters to filter the light around a number of wavelengths, image capture zones to receive filtered light from the filters and to generate data to represent the filtered light and an image and signal processing system to monitor time-varying physiological parameters of the subject indicated by the data.

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Номер записи: 22
12-12-2013 дата публикации

Pathlength Enhancement of Optical Measurement of Physiological Blood Parameters

Номер: US20130331710A1
Автор: Clark R. Baker, Jr., Youzhi Li
Принадлежит: Nellcor Puritan Bennett LLC

Systems and methods for measuring a physiological parameter of tissue in a patient are provided herein. In a first example, a method of measuring a physiological parameter of blood in a patient is provided. The method includes emitting at least two optical signals for propagation through tissue of the patient, detecting the optical signals after propagation, identifying propagation pathlengths of the optical signals, and identifying detected intensities of the optical signals. The method also includes processing at least the propagation pathlengths to scale the detected intensities for determination of a value of the physiological parameter.

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Номер записи: 23
19-12-2013 дата публикации

Apparatus And Method For Surgical Instrument With Integral Automated Tissue Classifier

Номер: US20130338479A1
Автор: Allende Pilar Beatriz Garcia, Conde Olga Maria, Krishnaswamy Venkataramanan, Lopez-Higuera José Miguel, PAULSEN Keith D., Pogue Brian William
Принадлежит:

A method and apparatus is described for optically scanning a field of view, the field of view including at least part of an organ as exposed during surgery, and for identifying and classifying areas of tumor within the field of view. The apparatus obtains a spectrum at each pixel of the field of view, and classifies pixels with a kNN-type or neural network classifier previously trained on samples of tumor and organ classified by a pathologist. Embodiments use statistical parameters extracted from each pixel and neighboring pixels. Results are displayed as a color-encoded map of tissue types to the surgeon. In variations, the apparatus provides light at one or more fluorescence stimulus wavelengths and measures the fluorescence light spectrum emitted from tissue corresponding to each stimulus wavelength. The measured emitted fluorescence light spectra are further used by the classifier to identify tissue types in the field of view. 1. An instrument for automated identification of tissue types and for providing guidance to a surgeon during surgical procedures comprising:a multi-wavelength optical system for projecting light from a source onto tissue to illuminate a confined spot of the tissue;a scanner for directing the illuminated spot across the tissue in raster form;a spectrally sensitive detector for receiving light from the optical system in order to produce measurements at a plurality of wavelengths from the illuminated spot on the tissue;a spectral processing classifier for determining a tissue type associated with each of a plurality of pixels of the image; anda display device for displaying the tissue type of the plurality of pixels of the image to the surgeon.2. The instrument of claim 1 , wherein the optical system is a multiwavelength claim 1 , confocal system.3. The instrument of claim 1 , further comprising apparatus for determining parameters from pixel spectra claim 1 , wherein the classifier classifies each pixel according to the parameters; and ...

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Номер записи: 24
26-12-2013 дата публикации

DETERMINATION BY INDEPENDENT COMPONENT ANALYSIS OF THE EFFICACY OF A TREATMENT

Номер: US20130345542A1
Автор: Descombes Xavier, Prigent Sylvain Mériadec, Zerubia Josiane, Zugaj Didier
Принадлежит:

A method is described for determining a value for quantifying the deviation from a mean value of a distribution of a divergence in severity between an initial instant and a later instant subsequent to the initial instant. 1. A method of determining a value for quantifying a deviation from a mean value of a distribution of a divergence in severity between an initial instant and a later instant subsequent to the initial instant , the severity depending on the contrast between zones receiving a treatment and zones receiving a vehicle , the method comprising the following steps:acquiring, for at least one patient, at in initial instant and at least one later instant subsequent to the initial instant, at least one hyperspectral image comprising at least one zone selected from the group consisting of a diseased zone receiving treatment, a healthy zone receiving treatment, a diseased zone receiving vehicle and a healthy zone receiving vehicle,determining a breakdown of the hyperspectral images into independent components,determining a representative component maximizing the divergence between healthy zone and pathological zone, for each image, from among the independent components,storing a linear combination of spectral bands corresponding to a representative component, for each image,determining the mean over all the images, of absolute values of the linear combinations of the spectral bands each corresponding to the representative component of an image,determining a representative component corrected as a function of the mean of the representative components for each image,determining a value of the divergence in severity as a function of the corrected representative components of the hyperspectral images acquired, for each patient and for each measurement instant, anddetermining a value for quantifying the deviation from the mean value between a distribution of the divergence in severity at the initial instant and a distribution of the divergence in severity at a later ...

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Номер записи: 25
02-01-2014 дата публикации

Binocular viewing assembly for a surgical visualization system

Номер: US20140005485A1
Автор: John Tesar, Steven T. Charles
Принадлежит: Camplex Inc

A surgical device includes a plurality of cameras integrated therein. The view of each of the plurality of cameras can be integrated together to provide a composite image. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the composite image generated by the plurality of cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as transparent on the composite image. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices.

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Номер записи: 26
02-01-2014 дата публикации

OPTICAL ASSEMBLY PROVIDING A SURGICAL MICROSCOPE VIEW FOR A SURGICAL VISUALIZATION SYSTEM

Номер: US20140005555A1
Автор: Tesar John
Принадлежит:

A surgical device includes a plurality of cameras integrated therein. The view of each of the plurality of cameras can be integrated together to provide a composite image. A surgical tool that includes an integrated camera may be used in conjunction with the surgical device. The image produced by the camera integrated with the surgical tool may be associated with the composite image generated by the plurality of cameras integrated in the surgical device. The position and orientation of the cameras and/or the surgical tool can be tracked, and the surgical tool can be rendered as transparent on the composite image. A surgical device may be powered by a hydraulic system, thereby reducing electromagnetic interference with tracking devices. 1. A surgical visualization system comprising:a binocular viewing assembly comprising a housing and a pair of eyepieces, said eyepieces configured to provide a view of at least one display disposed in the housing;an optical assembly disposed on the binocular viewing assembly, the optical assembly configured to provide a surgical microscope view of a surgical site, the optical assembly comprising at least one auxiliary camera;an articulating arm, the binocular viewing assembly disposed on the articulating arm, the articulating arm configured to adjust a position of the binocular viewing assembly and the optical assembly; andan image processing system in communication with the optical assembly and the display, the image processing system comprising at least one physical processor, receive video images acquired by the auxiliary camera,', 'provide output video images based on the received video images, and', 'present the output video images on the display so that the output video images are viewable through the eyepiece,, 'wherein the image processing system is configured towherein the optical assembly is configured to provide a working distance that is adjustable between about 15 cm and about 45 cm.2. The surgical visualization system of ...

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Номер записи: 27
02-01-2014 дата публикации

MOBILE VIDEO-BASED THERAPY

Номер: US20140007009A1
Автор: JR. Ronald L., Kulusky, Robinson Scott
Принадлежит: QUALCOMM INCORPORATED

Mobile video-based therapy, using a portable therapy device that includes a camera, a therapy application database, a processor, and a display. The camera is configured to generate images of a user, and the therapy application database is configured to store therapy applications. The processor is configured to select, from the therapy application database, a therapy application appropriate for assisting in physical or cognitive rehabilitation or therapy of the user, to invoke the therapy application, to recognize a gesture of the user from the generated images, and to control the invoked therapy application based on the recognized gesture. The display is configured to display an output of the controlled therapy application. 147.-. (canceled)48. A method comprising:determining, by a computing device, a medical condition of a user;selecting an application based on the determined medical condition;wherein determining a medical condition of the user includes:determining an identity of the user based on performing facial detection and recognition in a captured image from a capture device; andquerying a database that correlates users with medical conditions, using the determined identity.49. The method of claim 48 , further comprising:recognizing, by the computing device, whether the user possesses a controller based on information from the capture device,wherein the selecting the application is further based on whether the user possesses the controller.50. The method of claim 49 , wherein selecting the application comprises selecting an application that does not require possession of the controller claim 49 , if it is not recognized that the user possesses the controller.51. The method of claim 48 , wherein the capture device comprises a camera.52. The method of claim 48 , wherein the application is a therapy application appropriate for assisting in physical or cognitive rehabilitation of the user.53. The method of further comprising:recognizing a gesture of the user ...

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Номер записи: 28
16-01-2014 дата публикации

Methods for Stent Strut Detection and Related Measurement and Display Using Optical Coherence Tomography

Номер: US20140018669A1
Автор: Xu Chenyang
Принадлежит:

In one embodiment, the invention relates to a processor based method for generating positional and other information relating to a stent in the lumen of a vessel using a computer. The method includes the steps of generating an optical coherence image data set in response to an OCT scan of a sample containing at least one stent; and identifying at least one one-dimensional local cue in the image data set relating to the position of the stent. 120.-. (canceled)21. A method of detecting a stent in a lumen of a blood vessel comprising:storing an optical coherence tomography image data set comprising a plurality of scan lines in a memory device, the optical coherence tomography image data set generated in response to an optical coherence tomography (OCT) scan of the blood vessel; andidentifying at least one stent strut of the stent by detecting, using a processor, a one-dimensional local cue in one or more scan lines of the optical coherence tomography image data set anddisplaying a cross-sectional image of the blood vessel and one or more identified stent struts.22. The method of further comprising fitting an ellipse to a plurality of detected stent struts using the processor on a per frame basis.23. The method of further comprising removing detected stent struts that do not fit the ellipse.24. The method of further comprising determining a tilt claim 22 , a minor axis claim 22 , and major axis for each fitted ellipse on a per frame basis.25. The method of further comprising fitting an elliptical shape on a per frame basis as a result of average values obtained for the tilt claim 24 , center claim 24 , minor axis and minor axis.26. The method of further comprising averaging intensity values within each scan line within a region.27. The method of wherein the one dimensional local cue is an intensity profile.28. The method of wherein the one dimensional local cue is a shadow profile.29. The method of further comprisingdefining a depth below a lumen boundary in the optical ...

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Номер записи: 29
23-01-2014 дата публикации

ANNULAR VISION SYSTEM

Номер: US20140024951A1
Автор: Duindam Vincent, Herzlinger Peter M., Larkin David Q., Prisco Giuseppe Maria
Принадлежит:

A vision system that may be used in a catheter or similar guiding instrument includes receptors distributed in an annular area. Each of the receptors has a field of view covering only a portion of an object environment, and the field of view of each of the receptors overlaps with at least one of the fields of view of the other receptors. A processing system can receive image data from the receptors and combine image data from the receptors to construct a visual representation of the entirety of the object environment. 1. A system comprising:a plurality of receptors distributed in an annular area, wherein each of the receptors has a field of view covering only a portion of an object environment, and wherein the field of view of each of the receptors overlaps with at least one of the fields of view of the other receptors; anda processing system coupled to receive image data from the receptors, wherein the processing is configured to combine image data from the receptors to construct a representation of the object environment.2. The system of claim 1 , wherein each of the receptors comprises a lens and a distal end of an optical fiber.3. The system of claim 2 , further comprising:an image sensor; anda tube having a distal end and a proximal end, wherein the receptors are distributed on the distal end of the tube, and the optical fibers extend from the distal end to the proximal end of the tube where the optical fibers are positioned to project light onto the image sensor.4. The system of claim 2 , further comprising illumination fibers that positioned to project light into the object environment.5. The system of claim 1 , wherein each of the receptors comprises a lens and a distal end of a bundle containing a plurality of optical fibers.6. The system of claim 1 , wherein each of the receptors comprises an image sensor chip.7. The system of claim 6 , wherein each of the receptors further comprise an optical system having an optical axis that is offset from a center of ...

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Номер записи: 30
23-01-2014 дата публикации

Enhanced Laser Vein Contrast Enhancer with Projection of Analyzed Vein Data

Номер: US20140024952A1
Автор: Conlon Stephen, Goldman Ron, Luciano Vincent, Wood Fred
Принадлежит:

It is known in the art to use an apparatus to enhance the visual appearance of the veins and arteries in a patient to facilitate insertion of needles into those veins and arteries. This application discloses a number of inventions that add additional data collection and presentation capabilities to a handheld vein enhancement apparatus and a set of processes for the collection of blood and the delivery of IV medicines that use the handheld device to mediate the process. 1. A handheld system for assisting in the performance of a venipuncture procedure , said system comprising:a display means;a microprocessor, said microprocessor coupled to a memory, and thereby configured to access patient data stored therein and associated with a respective bar code, said patient data comprising patient identification data and required venipuncture data;a first laser configured to emit a beam of light at a first wavelength;a second laser configured to emit a beam of light at a second wavelength;an image capture means responsive to said first and second wavelengths of light;means for scanning, said means for scanning configured to scan said first wavelength of light, with said image capture means and said microprocessor thereby configured to decode a bar coded patient wrist band, and to provide said required venipuncture data corresponding to said bar code, upon said display means;said means for scanning further configured to scan said second wavelength of light in a pattern onto a target area of the patient to form a contrasted image of subcutaneous veins of the target area by differential absorption between the subcutaneous veins and the surrounding tissue therein, said image capture means further configured to output a signal representing said contrasted image to said second laser, with said means for scanning configured to receive said contrasted image from said second laser and to thereby scan said imaged subcutaneous veins in said contrasted image onto the target area using ...

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Номер записи: 31
20-02-2014 дата публикации

FLOWOMETRY IN OPTICAL COHERENCE TOMOGRAPHY FOR ANALYTE LEVEL ESTIMATION

Номер: US20140051952A1
Автор: Kechter George, Reichgott Samuel, Schurman Matthew J., Shakespeare Walter J., Wallace Phillip William
Принадлежит: GLT ACQUISITION CORP.

Optical coherence tomography (herein “OCT”) based analyte monitoring systems are disclosed. In one aspect, techniques are disclosed that can identify fluid flow in vivo (e.g., blood flow), which can act as a metric for gauging the extent of blood perfusion in tissue. For instance, if OCT is to be used to estimate the level of an analyte (e.g., glucose) in tissue, a measure of the extent of blood flow can potentially indicate the presence of an analyte correlating region, which would be suitable for analyte level estimation with OCT. Another aspect is related to systems and methods for scanning multiple regions. An optical beam is moved across the surface of the tissue in two distinct manners. The first can be a coarse scan, moving the beam to provide distinct scanning positions on the skin. The second can be a fine scan where the beam is applied for more detailed analysis. 1. A system for determining at least one blood characteristic in a tissue sample , comprising:an optical coherency tomography (OCT) apparatus configured to obtain intensity data measurements from each of a plurality of regions in the tissue sample; anda processor configured to analyze the intensity data measurements from the OCT apparatus to determine whether blood flow is present in at least one region.2. The system of claim 1 , wherein the processor is configured to convert the intensity data measurements into blood analyte levels from at least one of the regions determined to have a selected level of blood flow.3. The system of claim 1 , wherein the processor is configured to analyze speckle in the intensity data measurements.4. The system of claim 1 , wherein the processor is configured to compare speckle in different intensity data measurements to determine whether blood flow is present.5. The system of claim 4 , wherein the OCT apparatus is configured to provide the different intensity data measurements over a plurality of moments in time.6. The system of claim 4 , wherein the OCT apparatus ...

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Номер записи: 32
06-03-2014 дата публикации

System and method for quantifying or imaging pain using electrophysiological measurements

Номер: US20140066739A1
Автор: Bin He, Huishi Zhang
Принадлежит: Bin He, Huishi Zhang

A method for computing a quantitative metric indicative of pain experienced by a subject using an electrophysiological signal detection system is provided. Electrophysiological data are acquired from a subject with the electrophysiological signal detection system. Modulations in the acquired electrophysiological data that are associated with pain experienced by the subject during the acquisition of the electrophysiological data are identified. A quantitative metric indicative of the pain experienced by the subject is computed by processing the identified modulations in the acquired electrophysiological data.

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Номер записи: 33
13-03-2014 дата публикации

Diagnostic support apparatus and diagnostic support method

Номер: US20140072193A1
Автор: Hideto Motomura, Kazuki Kozuka, Yoshikuni Sato
Принадлежит: Panasonic Corp

The diagnostic support apparatus includes a feature quantity calculation unit vectorizing a test image into shift-invariant feature quantities, a base representation unit transforming the shift-invariant feature quantities of the test image into a linear combination of base vectors with first coefficients, the base vectors being calculated from a plurality of vectors representing shift-invariant feature quantities of a plurality of normal structural images including no lesion site, a lesion determination unit determining that the test image includes a lesion site when a difference between the first coefficients and second coefficients is greater than a determination threshold value, the second coefficients being used to transform shift-invariant feature quantities calculated from one of the normal structural images into a linear combination of the base vectors, and an output unit outputting a result of the determination by the lesion determination unit.

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Номер записи: 34
13-03-2014 дата публикации

Quantification of local circulation with oct angiography

Номер: US20140073917A1
Автор: David Huang, Jason Tokayer, Ou Tan, Yali Jia
Принадлежит: Oregon Health Science University

Impaired intraocular blood flow within vascular beds in the human eye is associated with certain ocular diseases including, for example, glaucoma, diabetic retinopathy and age-related macular degeneration. A reliable method to quantify blood flow in the various intraocular vascular beds could provide insight into the vascular component of ocular disease pathophysiology. Using ultrahigh-speed optical coherence tomography (OCT), a new 3D angiography algorithm called split-spectrum amplitude-decorrelation angiography (SSADA) was developed for imaging microcirculation within different intraocular regions. A method to quantify SSADA results was developed and used to detect perfusion changes in early stage ocular disease. Associated embodiments relating to methods for quantitatively measuring blood flow at various intraocular vasculature sites, systems for practicing such methods, and use of such methods and systems for diagnosing certain ocular diseases are herein described.

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Номер записи: 35
27-03-2014 дата публикации

Intra-operative molecular imaging

Номер: US20140088384A1
Автор: James Basilion
Принадлежит: CASE WESTERN RESERVE UNIVERSITY

A system for detecting tumor margins includes a topical protease-specific, fluorescence imaging probe that is activatable by enzymatic activation to produce a visually differentiated signal upon topical application to a targeted cancer cell that secretes an enzyme that activates the protease-specific, fluorescence imaging probe, means for topically administering the imaging probe to the cancer cell; and an imaging device to detect activation of the imaging probe administered to the cancer cell.

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Номер записи: 36
27-03-2014 дата публикации

FUNCTIONAL-IMAGING-BASED ABLATION MONITORING

Номер: US20140088418A1
Автор: Erkamp Ramon, HUANG SHENG-WEN, Jankovic Ladislav, Radulescu Emil, Shahzad Khalid, Shi Yan
Принадлежит: KONINKLIJKE PHILIPS N.V.

Functional imaging for localization in biological tissue entails measuring a response in the tissue () to electromagnetic radiation. A catheter () for real-time monitoring of cardiac ablation is employed to distinguish a hemorrhage zone () from the sandwiching necrotic and healthy tissue, or to distinguish exogenous photoacoustic contrast agent from bordering native tissue. A pair of wavelengths is selected for differential absorption () of the radiation in, correspondingly, the hemorrhage zone or where the contrast agent exists, and relatively similar absorption elsewhere. Near infrared laser or LED light may be used photoacoustically to serially acquire (S S) the two datasets to be compared, each representative of a time waveform. Alternatively, acquisition is for a pair of wavelength bands of microwave-induced thermoacoustic data. In either case, the members of the dataset pair are combined () by subtraction or division to effect the piece-wise cancellation/enhancement for display () of the resulting signal in real time. 1. An apparatus configured for using functional imaging for localization of biological tissue , said apparatus comprising:a processor for measuring responses in the biological tissue to electromagnetic radiation and distinguishing borders within the biological tissue of one or more of (i) a hemorrhage zone, disposed between (i)(a) healthy tissue and (i)(b) ablated tissue, from said healthy and ablated tissue, and (ii) a contrast agent from bordering native tissue, based upon the responses, wherein distinguishing the borders comprises combining, via the processor, datasets acquired, via a transducer, by electromagnetic irradiation, via an emitter, at different frequencies or frequency bands, wherein the datasets serve as measures of absorption by said biological tissue of the electromagnetic radiation, and wherein the different frequencies or frequency bands are (iii) selected for (iii)(a) differential absorption of radiation in, correspondingly, ...

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Номер записи: 37
27-03-2014 дата публикации

APPARATUS AND METHOD FOR FLUORESCENCE IMAGING AND TOMOGRAPHY USING SPATIALLY STRUCTURED ILLUMINATION

Номер: US20140088438A1
Автор: Feke Gilbert, Voci Laurie L.
Принадлежит: Bruker Biospin Corporation

An imaging system for imaging an object. More specifically, an imaging system enabling depth sectioned fluorescence imaging in a turbid medium, such as human or animal tissue, to substantially minimize the excitation radiation from reaching the detection beam path. The imaging system includes an arrangement of the excitation radiation source wherein the optical axis of the source is inclined relative to the optical axis of the camera, the optical plane of the source and the optical plane of the object are subject to a Scheimpflug condition, and the angle of inclination of the source is selected such that the excitation radiation incident upon the object is reflected to minimize excitation radiation from reaching the detection beam path. 1. An apparatus for quantitative modulated fluorescence imaging to perform depth sectioned fluorescence imaging of a turbid sample including a fluorescent turbid medium , the apparatus including projection optics , including a first optical axis , to expose the turbid sample to a periodic pattern of excitation radiation to provide depth-resolved discrimination of fluorescent structures within the turbid medium; an image capture module , including a second optical axis and a detection beam path , to receive a data image from the sample; and a signal processor to transform the data image from the sample , spatially filter the transformed data image from the sample , and reconstruct the filtered , transformed data image from the sample; the improvement comprising:an arrangement whereby the first optical axis is inclined relative to the second optical axis;the projection optics including an object plane and an image plane that are subject to a Scheimpflug condition;the periodic pattern of excitation radiation having periodicity in a direction perpendicular to a direction of a projection of the first optical axis onto the image plane, so that the phase of the periodic pattern of excitation radiation does not change with increasing depth ...

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Номер записи: 38
27-03-2014 дата публикации

Stereoscopic Plug-And-Play Dermatoscope And Web Interface

Номер: US20140088440A1
Автор: Asai Elizabeth Mary, Demas Nickolas Peter, Swart Elliot Krishna
Принадлежит:

A system includes a device () for imaging a skin abnormality of a patient, and a web interface (). The imaging device has a camera () recording a plurality of images from locations separated by that distance, thereby obtaining a stereoscopic image of the skin abnormality. The imaging device may be configured as a handheld unit, with the camera a plug-and-play webcam and the device having a USB connection () to a computer (). The web interface () links the computer () to a web site providing access to storage of the image data. The web interface provides a patient portal for entering information regarding the skin abnormality, and a doctor portal for accessing patient medical history and entering clinical data regarding the skin abnormality. The system may further include a server () to receive and analyze the image data, generate 3D stereoscopic images of the skin abnormality, and compute metrics for clinical evaluation of the skin abnormality. 1. A system comprising: a camera; and', 'a controller for controlling linear motion of the camera over a predetermined distance so that the camera records a plurality of images from locations separated by said distance, thereby obtaining a stereoscopic image of the skin abnormality;, 'an imaging device for imaging a skin abnormality of a patient, including'}a data path for transmission of image data to a computing device; anda web interface for linking the computing device to a web site providing access to storage of the image data.2. A system according to claim 1 , wherein the imaging device further includesa track for mounting the camera thereon, anda servo motor, connected to the camera and to the controller, for causing said linear motion along the track.3. A system according to claim 1 , wherein the camera includes LED illumination and a first polarizing filter.4. A system according to claim 3 , wherein the imaging device includes a second polarizing filter with polarization orthogonal to that of the first polarizing ...

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Номер записи: 39
27-03-2014 дата публикации

Noninvasive method for determining the presence of systemic hypertension in a subject

Номер: US20140088441A1
Автор: Christopher J. Kolanko, James E. Smith, James Vernon Odom, Lance Molnar
Принадлежит: Christopher J. Kolanko, James E. Smith, James Vernon Odom, Lance Molnar

A non-invasive method for determining and characterizing the presence of damage or abnormalities resulting from or concomitant with systemic hypertension in subject. This method is comprised of the acquisition of ocular image(s) and subsequent evaluation, classification and/or interpretation of these image(s). The ocular image(s) may be acquired by photography. Evaluation, classification, and/or interpretation may be automated or involve the active participation of a human. The ocular images may be classified into either a normal or clinical group or compared to an algorithm of hypertensive symptoms. The ocular images may, additionally, be processed and have the pertinent characteristics extracted to make the classification more exact.

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Номер записи: 40
03-04-2014 дата публикации

System and Method of Predicting Future Fractures

Номер: US20140093149A1
Автор: Arnaud Claude D., Lang Philipp, Liew Siau-Way, Steines Daniel, Vargas-Voracek Rene
Принадлежит: IMATX, INC.

Methods of predicting fracture risk of a patient include: obtaining an image of a bone of the patient; determining one or more bone structure parameters; predicting a fracture line with the bone structure parameter; predicting a fracture load at which a fracture will happen; estimating body habitus of the patient; calculating a peak impact force on the bone when the patient falls; and predicting a fracture risk by calculating the ratio between the peak impact force and the fracture load. Inventive methods also include determining the effect of a candidate agent on any subject's risk of fracture. 1. A method for predicting fracture risk using electronic image data of a part of a skeleton of a target in a computer system , the method comprising:performing a sliding window analysis of the electronic image data;generating at least one bone structure parameter corresponding to at least a portion of the target;generating a parameter map from the at least one bone structure parameter to predict a fracture line;analyzing the at least one bone structure parameter along the predicted fracture line to predict a fracture load at which a fracture will occur; andpredicting a fracture risk by calculating a ratio between the fracture load and a peak impact force on the part of the skeleton of the target.2. The method of claim 1 , wherein the peak impact force is estimated.3. The method of claim 1 , wherein the peak impact force is calculated.4. The method of claim 1 , further including obtaining a body habitus of the target and using the body habitus to estimate or calculate the peak impact force. This patent application is a continuation of U.S. patent application Ser. No. 11/228,126, filed Sep. 16, 2005, now U.S. Pat. No. 8,600,124, which claims the benefit of U.S. Patent Application Ser. No. 60/610,447, filed Sep. 16, 2004, the disclosures of which are incorporated by reference herein in its entireties.1. Field of the InventionThis invention relates to using imaging methods for ...

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Номер записи: 41
03-04-2014 дата публикации

OPTICAL COHERENCE TOMOGRAPHY AND PRESSURE BASED SYSTEMS AND METHODS

Номер: US20140094697A1
Автор: PETROFF Christopher, Schmitt Joseph
Принадлежит: LIGHTLAB IMAGING, INC.

In part, the invention relates to methods, apparatus, and systems suitable for determining a fractional flow reserve (FFR) and variations of modifications thereof One embodiment relates to a method and apparatus for obtaining a corrected FFR in a vessel having a stenosis. In one aspect, the invention relates to an apparatus for measuring corrected FFR of a vessel having a stenosis. In one embodiment, the apparatus includes a probe comprising an optical coherence tomography assembly and a pressure assembly; and a processor in communication with the optical coherence tomography assembly and the pressure assembly. In one embodiment, the pressure assembly measures values of pressure in predetermined locations the vessel and communicates them to the processor. In one embodiment, a dual guidewire is used to reduce the interference in the pressure measurement. 1. A data collection system comprising:a pressure assembly configured to measure pressure at one or more predetermined locations in a vessel, andan optical coherence tomography assembly configured to measure a geometry of the vessel at one or more of the predetermined locations within the vessel.2. The system of further comprising a probe claim 1 , wherein the optical coherence tomography assembly is disposed in the probe.3. The system of wherein the optical coherence tomography assembly comprises an optical fiber claim 2 , wherein the probe further comprisesa first torque wire having a first diameter and defining a first lumen anda second torque wire having a second diameter and defining a second lumen,wherein the first and second torque wires are joined, andwherein the optical fiber passes through the first lumen and the second lumen.4. The system of further comprising a probe claim 1 , wherein the optical coherence tomography assembly is disposed in the probe claim 1 , the optical coherence tomography assembly comprisesan optical fiber configured to transmit light of a first wavelength band and a second wavelength ...

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Номер записи: 42
03-04-2014 дата публикации

Imaging Systems and Methods

Номер: US20140095094A1
Автор: Frank Hermann Sotzik, Javier Andre Leicester, Venkateswara S. Venkatesan
Принадлежит: Individual

In one preferred form of the present invention, there is provided method 10 of generating at least one image. The method 10 includes applying electrical signals to an individual at various spaced apart nodes; measuring impedance related data between a number of the nodes; and using the impedance related data to generate three dimensional image data.

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Номер записи: 43
03-01-2019 дата публикации

ACOUSTIC WAVE DETECTION PROBE AND PHOTOACOUSTIC MEASUREMENT APPARATUS PROVIDED WITH THE SAME

Номер: US20190000323A1
Автор: IRISAWA Kaku
Принадлежит: FUJIFILM Corporation

In an acoustic wave detection probe provided with a light guide section that guides measuring light such that the measuring light is outputted toward a subject and an acoustic wave transducer that detects a photoacoustic wave generated in the subject by the projection of the measuring light, the light guide section includes a homogenizer that flat-tops an energy profile of the measuring light entered from the upstream side of the optical system, a light condensing member that condenses the measuring light transmitted through the homogenizer, and a bundle fiber which includes a plurality of optical fibers and is disposed such that the measuring light transmitted through the light condensing member enters from an entrance end of the bundle fiber. 2. A photoacoustic measuring apparatus as defined in claim 1 , wherein:the homogenizer is a light shaping diffuser in which small lenses are disposed randomly on one side of a substrate so that the measuring light is further diffused.3. A photoacoustic measuring apparatus as defined in claim 1 , wherein:the holding section is configured to hold the entrance end portion of the optical fibers so as to cover the input surface of the bundle fiber, and the holding section has a window at a portion at which the measuring light enters.4. A photoacoustic measuring apparatus as defined in claim 3 , wherein:the window is constituted by an ND filter.5. A photoacoustic measuring apparatus as defined in claim 1 , further comprising:an aperture member having an aperture that allows the measuring light, which is to enter the bundle fiber, to pass through and is provided at the entrance end of the bundle fiber, and gradually reduces the diameter of the aperture toward the entrance end to a size corresponding to the diameter of the bundle fiber.6. A photoacoustic measuring apparatus as defined in any one of claim 1 , wherein:the holding section includes therein a light guide member formed of a cap member and a ring shaped chip made of a ...

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Номер записи: 44
02-01-2020 дата публикации

SYSTEMS AND METHODS FOR DYNAMICALLY IDENTIFYING A PATIENT SUPPORT SURFACE AND PATIENT MONITORING

Номер: US20200000376A1
Автор: Chapman Kenneth, Clark Matt, del Carpio Derek
Принадлежит:

Various patient monitoring systems can include a sensor configured to collect three dimensional information. The systems can identify a location of a patient support surface based on the three dimensional information. The systems can set a two dimensional planar threshold based on the patient support surface. The systems can identify a patient location above the patient support surface based on the three dimensional information and compare the patient location to the two dimensional planar threshold. Exceeding the threshold can be indicative of a high risk of a patient fall. An alert can be generated based on the threshold being exceeded. The systems can repeat the identification of the patient support surface location and the setting of the threshold to account for changes in the patient area. 132-. (canceled)33. A patient monitoring system for monitoring a patient area , the system comprising:a sensor configured to output a plurality of frames, the plurality of frames containing three dimensional pixel information of the patient area;a user interface; and receive the three dimensional pixel information of the plurality of frames;', 'identify a location and dimensions of a patient support surface based on the three dimensional pixel information;', 'set at least one threshold that is extended above, below, or vertically beyond the location and dimensions of the patient support surface;', 'determine a repositioning of the patient support surface;', 'adjust the at least one threshold based on the repositioning of the patient support surface;', 'identify one or more patient locations based on the three dimensional pixel information;', 'compare the one or more patient locations to the at least one threshold; and', 'generate an output with the user interface based on the one or more patient locations traversing the at least one threshold., 'control circuitry configured to34. The patient monitoring system of claim 33 , wherein the control circuitry is configured to:detect ...

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Номер записи: 45
07-01-2016 дата публикации

NON-TOUCH OPTICAL DETECTION OF VITAL SIGNS FROM AMPLIFIED VISUAL VARIATIONS

Номер: US20160000327A1
Автор: Khachaturian Mark, Smith Michael G.
Принадлежит: Arc Devices, LTD

A microprocessor is operably coupled to a camera from which patient vital signs are determined. A temporal-variation-amplifier of at least two images is operable to generate a temporal variation, a vital-sign generator is operable to generate at least one vital sign from the temporal variation and a display device is operable to display the at least one vital sign. 1. An apparatus of motion amplification to communicate biological vital signs , the apparatus comprising:a skin-pixel-identifier that identifies pixel values that are representative of the skin in at least two images;a spatial bandpass filter that is operably coupled to the skin-pixel-identifier and that processes output of the skin-pixel-identifier;a regional facial clusterial module that is operably coupled to the spatial bandpass filter and that applies spatial clustering to the output of the spatial bandpass filter;a temporal bandpass filter that is operably to the regional facial clusterial module and that is applied to output of the regional facial clusterial module;a temporal-variation identifier that is operably coupled to the temporal bandpass filter and that identifies temporal variation of the output of the temporal bandpass filter;a vital-sign generator that is operably coupled to the temporal-variation identifier that generates at least one vital sign from the temporal variation; anda display device that is operably coupled to the vital-sign generator that is operable to display the at least one vital sign.2. The apparatus of claim 1 , wherein the skin-pixel-identifier further comprises:an automatic seed point based clustering apparatus.3. The apparatus of claim 1 , wherein the regional facial clusterial module further comprises:a fuzzy clusterer.4. The apparatus of claim 1 , wherein the spatial bandpass filter further comprises:a one-dimensional spatial Fourier Transformation apparatus.5. The apparatus of claim 1 , wherein the spatial bandpass filter further comprises:a high pass filter.6. ...

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Номер записи: 46
07-01-2016 дата публикации

NON-TOUCH OPTICAL DETECTION OF VITAL SIGNS FROM AMPLIFIED VISUAL VARIATIONS OF REDUCED IMAGES

Номер: US20160000328A1
Автор: Khachaturian Mark, Smith Michael G.
Принадлежит: Arc Devices, LTD

A microprocessor is operably coupled to a camera from which patient vital signs are determined from reduced images. A temporal-variation-amplifier of at least two reduced images is operable to generate a temporal variation, a vital-sign generator is operable to generate at least one vital sign from the temporal variation and a display device is operable to display the at least one vital sign. 1. An apparatus of motion amplification to communicate biological vital signs , the apparatus comprising:a cropper that is operable to receive at least two images and crop the image to exclude a border area of the images, generating at least two cropped images;a skin-pixel-identifier that is operably coupled to the cropper and that identifies pixel values that are representative of the skin in at least two cropped images;a first frequency filter that is operably coupled to the skin-pixel-identifier and that applies a frequency filter to output of the skin-pixel-identifier;a regional facial clusterial module that is operably coupled to the first frequency filter and that applies spatial clustering to the output of the first frequency filter; —a second frequency filter that is operably regional facial clusterial module and that is applied to the output of the regional facial clusterial module;a temporal-variation identifier that is operably coupled to the second frequency filter and that identifies temporal variation of the output of the second frequency filter;a vital-sign generator that is operably coupled to the temporal-variation identifier that generates at least one vital sign from the temporal variation; anda display device that is operably coupled to the vital-sign generator that is operable to display the at least one vital sign.2. The apparatus of claim 1 , wherein the regional facial clusterial module further comprises:a fuzzy clusterer.3. The apparatus of claim 1 , wherein the first frequency filter further comprises:a one-dimensional spatial Fourier Transformation ...

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Номер записи: 47
07-01-2016 дата публикации

WIDE FIELD RAMAN IMAGING APPARATUS AND ASSOCIATED METHODS

Номер: US20160000329A1
Автор: Kircher Moritz, Toledo-Crow Ricardo
Принадлежит: Sloan-Kettering Institute for Cancer Research

Apparatus and methods are presented herein that permit real-time, accurate detection of residual tumor in the operating room. The Raman-based wide-field imaging apparatus and methods described herein permit real-time imaging of tumor-targeted R-MR nanoparticles over a wide field. 1. A wide field Raman imaging apparatus comprising:at least one light source for producing excitation light;optics for directing the excitation light onto and/or into a target tissue;a detector for detecting Raman scattered photons emanating from the target tissue following illumination by the excitation light, the Raman scattered photons indicative of the presence of a Raman reporter in and/or upon the target tissue; anda processor configured to process data corresponding to the Raman scattered photons detected from the target tissue and to produce an image depicting a wide field corresponding to the target tissue, the image visually indicating position and/or intensity of the Raman reporter within the wide field.2. The apparatus of claim 1 , wherein the at least one light source claim 1 , the detector claim 1 , and the processor are configured to produce a substantially real-time series of images visually indicating position and/or intensity of the Raman reporter within the wide field.3. The apparatus of claim 2 , wherein the processor is configured to produce each image of the real-time series of images by obtaining one or more monochromatic images within a given short interval of time (e.g. claim 2 , 500 milliseconds or less claim 2 , e.g. claim 2 , 50 milliseconds or less) claim 2 , each monochromatic image obtained at a wavelength corresponding to a spectral peak characteristic of the Raman reporter claim 2 , and to use the one or more monochromatic images to produce the image in the real-time series indicating the position and/or intensity of the Raman reporter within the wide field during the given short interval of time.4. The apparatus of any one of the preceding claims claim 2 , ...

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Номер записи: 48
07-01-2016 дата публикации

APPARATUS OF NON-TOUCH OPTICAL DETECTION OF VITAL SIGNS OF REDUCED IMAGES FROM SPATIAL AND TEMPORAL FILTERS

Номер: US20160000331A1
Автор: Khachaturian Mark, Smith Michael G.
Принадлежит: Arc Devices, LTD

A microprocessor is operably coupled to a camera from which patient vital signs are determined. A temporal variation of images from the camera is generated and amplified from which the patient vital sign, such as heart rate or respiratory rate, can be determined and displayed or stored. 1. An apparatus of motion amplification to communicate biological vital signs , the apparatus comprising:a cropper that is operable to receive at least two images and operable to crop the images to exclude a border area of the images, generating at least two cropped images;a temporal-variation-amplifier of the at least two cropped images that is operable to generate a temporal variation;a vital-sign generator that is operably coupled to the temporal-variation-amplifier that is operable to generate at least one vital sign from the temporal variation; anda display device that is operably coupled to the vital-sign generator that is operable to display the at least one vital sign.2. The apparatus of claim 1 , wherein the temporal-variation-amplifier further comprises:a skin-pixel-identifier that identifies pixel values that are representative of the skin in the at least two images; anda first frequency filter that is operably coupled to the skin-pixel-identifier and that is applied to output of the skin-pixel-identifier.3. The apparatus of claim 2 , wherein the temporal-variation-amplifier further comprises:a regional facial clusterial module that is operably coupled to the first frequency filter and that applies spatial clustering to the output of the first frequency filter; anda second frequency filter that is operably regional facial clusterial module and that is applied to output of the regional facial clusterial module, generating the temporal variation.4. The apparatus of claim 2 , wherein the regional facial clusterial module further comprises:a fuzzy clusterer.5. The apparatus of claim 2 , wherein the first frequency filter further comprises:a one-dimensional spatial Fourier ...

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Номер записи: 49
07-01-2021 дата публикации

NEUROLOGICAL EXAMINATION SYSTEM

Номер: US20210000350A1
Автор: HAAF JOEL, Zagorchev Lyubomir Georgiev
Принадлежит:

Systems and methods for evaluating an anatomical structure in a brain of a subject are provided. In an embodiment, a system for evaluating an anatomical structure in a brain of a subject includes a computing device in communication with a magnetic resonance imaging (MRI) device. The computing device operable to determine an abnormality in the anatomical structure by comparing a test activation level within a geometry of the anatomical structure to data in a normative database, and output, to a display device, a graphical representation of the abnormality in the anatomical structure. The test activation level is determined by aligning functional magnetic resonance imaging (fMRI) data obtained by use of the MRI device and the geometry of the anatomical structure. The geometry of the anatomical structure is delineated based on segmentation of magnetic resonance (MR) data obtained by use of the MRI device. The data in the normative database include activation levels of the anatomical structure of a plurality of neurologically non-diseased subjects.

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Номер записи: 50
03-01-2019 дата публикации

DEVICE, SYSTEM AND METHOD FOR GENERATING A PHOTOPLETHYSMOGRAPHIC IMAGE CARRYING VITAL SIGN INFORMATION OF A SUBJECT

Номер: US20190000391A1
Автор: ANDREIA Moco, De Haan Gerard
Принадлежит:

The present invention relates to a device, system and a method for generating a photoplethysmographic image carrying vital sign information of a subject. To provide an increased validity and robustness against motion, in particular against ballistocardiographic motion, the proposed device comprises an input interface () for obtaining image data of a skin region of a subject in at least two different wavelength channels, said image data comprising two or more image frames acquired by detecting light transmitted through or reflected from the skin region over time, wherein said image data comprise wavelength-dependent reflection or transmission information in said at least two different wavelength channels, a combination unit () for combining, per pixel or group of pixels and per time instant, image data values of said at least two different wavelength channels to obtain a time-variant pulse signal per pixel or group of pixels, and an image generation unit () for generating a photoplethysmographic image from a property of the respective pulse signals in a time window including at least two image frames. 1. A device for generating a photoplethysmographic image carrying vital sign information of a subject , said device comprising:an input interface for obtaining image data of a skin region of a subject in at least two different wavelength channels, said image data comprising two or more image frames acquired by detecting light transmitted through or reflected from the skin region over time, wherein said image data comprise wavelength-dependent reflection or transmission information in said at least two different wavelength channels,a combination unit for combining, per pixel or group of pixels and per time instant, image data values of said at least two different wavelength channels to obtain a time-variant pulse signal per pixel or group of pixels, wherein said combination unit is configured to combine the image data values of said at least two different wavelength ...

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Номер записи: 51
07-01-2016 дата публикации

SYSTEMS AND METHODS FOR IN VIVO VISUALIZATION OF LYMPHATIC VESSELS WITH OPTICAL COHERENCE TOMOGRAPHY

Номер: US20160000368A1
Автор: BARAN Utku, Wang Ruikang K., YOUSEFI Siavash
Принадлежит:

The present technology relates generally to systems and methods for in vivo visualization of lymphatic vessels. A system includes an optical coherence tomography (OCT) device and a computing device coupled to the OCT device configured to cause the OCT device to perform an OCT scan, generate image data in response to the OCT scan, and apply an eigendecomposition filter to the image data to produce processed image data. Alternatively or in addition, the computing device can compensate for scattering attenuation along an optical axis of the OCT scan in the image data set to generate compensated image data, enhance contrast of the compensated image data along a cross-section substantially orthogonal to the optical axis to generate contrast-enhanced image data, and identify at least one lymphatic vessel in the image data. 1. A system , comprising:an optical coherence tomography (OCT) device;a processor coupled to the OCT device; initiating an OCT scan with the OCT device;', 'generating image data in response to the OCT scan; and', 'applying an eigendecomposition filter to the image data to produce processed image data; and, 'a computer-readable medium storing instructions that, when executed by the processor, cause the processor to perform operations, the operations comprisinga display coupled to the processor and configured to display the processed image data.2. The system of wherein the eigendecomposition filter comprises a Hessian vesselness filter.3. The system of wherein the operations further comprise identifying at least one lymphatic vessel based on the processed image data.4. The system of wherein the operations further comprise generating a three-dimensional map of the lymphatic vessel.5. A method of visualizing lymphatic vessels in a body of a human patient claim 3 , the method comprising:generating an optical coherence image data set in response to an optical coherence tomography (OCT) scan of a portion of the body containing at least one lymphatic vessel; ...

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Номер записи: 52
07-01-2016 дата публикации

Apparatus of non-touch optical detection of vital signs from multiple filters

Номер: US20160000381A1
Автор: Mark Khachaturian, Michael G. Smith
Принадлежит: ARC Devices Ltd

A microprocessor is operably coupled to a camera from which patient vital signs are determined. A temporal variation of images from the camera is generated from multiple filters and then amplified from which the patient vital sign, such as heart rate or respiratory rate, can be determined and then displayed or stored.

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Номер записи: 53
04-01-2018 дата публикации

SKIN EVALUATION APPARATUS, SKIN EVALUATION METHOD, AND SKIN EVALUATION PROGRAM

Номер: US20180000349A1
Автор: IKEDA Eriko, Ishibashi Hideyasu, Tani Takeharu, YAMAGUCHI Yoshitaka, Yoshida Naoko
Принадлежит: FUJIFILM Corporation

Provided are a skin evaluation apparatus, a skin evaluation method, and a non-transitory computer readable recording medium storing a skin evaluation program capable of evaluating gloss of skin in consideration of both of a physical feature of the skin and an optical feature of the skin to quantitatively evaluate gloss of the skin closer to a practical point of view. The skin evaluation apparatus includes a shape information acquisition unit 22 that acquires information on a surface unevenness shape of the skin; an optical feature information acquisition unit 23 that acquires information on an optical feature of the skin; and an evaluation unit 24 that evaluates gloss of the skin on the basis of the information on the surface unevenness shape and the information on the optical feature. 1. A skin evaluation apparatus comprising:a shape information acquisition unit that acquires information on a surface unevenness shape of skin;an optical feature information acquisition unit that acquires information on an optical feature of the skin; andan evaluation unit that evaluates gloss of the skin on the basis of the information on the surface unevenness shape and the information on the optical feature.2. The skin evaluation apparatus according to claim 1 ,wherein the shape information acquisition unit acquires an image obtained by imaging the skin and acquires the information on the surface unevenness shape on the basis of the acquired image.3. The skin evaluation apparatus according to claim 1 ,wherein the shape information acquisition unit acquires an image obtained by imaging peeling of stratum corneum taken from the skin and acquires the information on the surface unevenness shape on the basis of the acquired image.4. The skin evaluation apparatus according to claim 1 ,wherein the shape information acquisition unit reads and acquires the information on the surface unevenness shape of the skin which is stored in advance in a data server apparatus.5. The skin evaluation ...

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Номер записи: 54
04-01-2018 дата публикации

Biological information detection device using second light from target onto which dots formed by first light are projected

Номер: US20180000359A1
Автор: Hisashi Watanabe
Принадлежит: Panasonic Intellectual Property Management Co Ltd

A biological information detection device includes a light source, an image capturing device, and one or more arithmetic circuits. The light source projects dots formed by light onto a target including a living body. The image capturing device includes photodetector cells and generates an image signal representing an image of the target onto which the dots are projected. The one or more arithmetic circuits detect a portion corresponding to at least a part of the living body in the image by using the image signal and calculate biological information of the living body by using image signal of the portion.

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Номер записи: 55
04-01-2018 дата публикации

NONINVASIVE METHOD AND SYSTEM FOR ESTIMATING MAMMALIAN CARDIAC CHAMBER SIZE AND MECHANICAL FUNCTION

Номер: US20180000374A1
Автор: Burton Timothy William Fawcett, Exner Derek, Gupta Sunny, Ramchandani Shyamlal, Yazdi Mohsen Najafi
Принадлежит:

The present disclosure generally relates to systems and methods and systems of a noninvasive technique for characterizing cardiac chamber size and cardiac mechanical function. A mathematical analysis of three-dimensional (3D) high resolution data may be used to estimate chamber size and cardiac mechanical function. For example, high-resolution mammalian signals are analyzed across multiple leads, as 3D orthogonal (X,Y,Z), or 10-channel data, for 30 to 800 seconds, to derive estimates of cardiac chamber size and cardiac mechanical function. Multiple mathematical approaches may be used to analyze the dynamical and geometrical properties of the data. 119.-. (canceled)20. A system to noninvasively estimate a subject's cardiac chamber size and cardiac mechanical function , including left ventricular ejection fraction , the system comprising:a processor; and ["obtain orthogonal data from an acquired measurement of one more surface electrical signals of the subject, wherein the orthogonal data have been obtained from measurements acquired via noninvasive equipment configured to measure electrical properties of the subject's heart;", 'determine, via a numerical integral operation of one or more vectorcardiogram components associated with a vectorcardiogram of the orthogonal data, at least one value of one or more first parameters selected from the group consisting of a sum QRST integral parameter, a 3D volume integral parameter, a spatial QRST angle parameter, a 3D QRS loop volume parameter, a 3D T-loop volume parameter, a spatial ventricular gradient parameter, a spatial ventricular gradient azimuth parameter, and a spatial ventricular gradient elevation parameter;', 'determine at least one value of an estimated cardiac chamber size parameter by applying the at least one value of the one or more first parameters and the at least one value of the one or more second parameters in one or more first models associated with the cardiac chamber size; and', 'determine at least one ...

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Номер записи: 56
05-01-2017 дата публикации

Micro-Camera Based Health Monitor

Номер: US20170000392A1
Автор: SMITH FRASER
Принадлежит:

A camera coupled to a processor is disclosed. The camera is configured to capture images of the subject. The processor is configured to amplify microscopic temporal variations between the images of the subject and generate a profile of at least one microscopic temporally detected physiological variation of the tissues of the subject. The processor is further configured to compare the profile of the subject to a pre-existing profile of the subject and/or an aggregate profile of a plurality of third-party subjects, said aggregate profile corresponding to the at least one microscopic temporally detected physiological variation of the third-party subjects, the aggregate third-party profile corresponding to a known state of the tissue of the third-party subjects. 1. A wearable device configured to monitor a physiological condition of a subject , comprising:a wearable camera having a coupling member configured to attach the camera to a portion of the subject, the camera configured to capture a plurality of images of a portion of a tissue of the subject;a processor in communication with the camera, said processor comprising executable code configured to amplify microscopic temporal variations between the plurality of images of the tissue of the subject and generate a profile of at least one microscopic temporally detected physiological variation of the tissue of the subject and store the profile in a database; andwherein the processor is further configured to compare the profile of the tissue of the subject with a database corresponding to previous profiles of the at least one microscopic temporally detected physiological variation of the tissue of the subject.2. The device of claim 1 , wherein the processor is further configured to compare the profile of the tissue of the subject to an aggregate profile of a first plurality of third-party subjects claim 1 , said aggregate profile of the first plurality of third-party subjects corresponding to the at least one microscopic ...

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Номер записи: 57
04-01-2018 дата публикации

SELF-OPERABLE, NON-INVASIVE, NON-CONTACT BIO-SIGNAL MONITORING

Номер: US20180000415A1
Автор: Gupta Kavita Shashank, Gupta Subhanshu
Принадлежит:

Unique methods and bio-imaging systems are introduced herein for self-automated self-operable biomedical devices and methods for bio-signal monitoring, such as electrocardiograms (ECG), heart rate, and other vital signs, requiring no trained medical assistance or minimal assistance. In particular, methods and devices disclosed herein may require no dedicated medical resources, generate diagnostic quality results, and provide for motion artifact correction without inducing discomfort or irritation. Moreover, long term recording is realizable. Such methods and devices reduce the backlog of patients at out-patient wards as well as emergency response in remote areas. 1. A system for assisted sensor placement for bio-signal monitoring , comprisinga plurality of sensors fixable to an article worn by a subject;an imaging device positioned at a distance from the subject configured to capture an image of the subject;one or more computer-readable storage media containing anatomical reference data and computer-readable instructions; and determining target sensor positions on the article worn by the subject based on subject anatomy in the image captured with the imaging device and the anatomical reference data,', 'determining actual sensor positions of the plurality of sensors, and', 'comparing the target sensor positions with the actual sensor positions; and, 'one or more processors that, upon execution of the computer-readable instructions, perform steps comprising'}an output device for providing results of the comparison to the subject.2. The system of claim 1 , wherein the plurality of sensors are non-contact electrodes.3. The system of claim 1 , wherein the output device is a display for showing the results of the comparison to the subject on a screen.4. The system of claim 1 , wherein the one or more processors perform the step of determining actual sensor positions based on image processing of the image captured with the imaging device.5. The system of claim 4 , wherein ...

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Номер записи: 58
04-01-2018 дата публикации

Classifying hormone receptor status of malignant tumorous tissue from breast thermographic images

Номер: US20180000462A1
Автор: Himanshu J. MADHU, Krithika Venkataramani, Siva TEJA KAKILETI
Принадлежит: Niramai Health Analytix Pvt Ltd

What is disclosed is a system and method for classifying the hormone receptor status of malignant tumorous tissue identified in a thermographic image of a breast. One embodiment of the present method involves the following. First, receive thermographic image(s) of both breasts of a patient with a malignant tumorous region and analyzing the image(s) to define a boundary contour of the breast. Then, the breast regions are segment into regions of elevated temperature. A function of first probability mass function Q, ƒ(Q), is determined based on temperatures of pixels within a first segmented region. A function of the second probability mass function P, ƒ(P), is determined based on temperatures of pixels within a second region. A distance measure between the two functions ƒ(Q) and ƒ(P) is calculated and provided to a classifier trained to classify the malignant tissue as hormone receptor positive, and negative otherwise, based on the distance measure.

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Номер записи: 59
05-01-2017 дата публикации

SYSTEM FOR MEASURING LOWER EXTREMITY MUSCLE STRENGTH

Номер: US20170000402A1
Автор: LEE Yang Soo, MOON Sang Jun
Принадлежит:

The present invention relates to a system for measuring lower extremity muscle strength, and more particularly, to a system for measuring lower extremity muscle strength which can effectively measure or train lower extremity muscle strength by means of a simpler method. 1. A system for measuring lower extremity muscle strength , comprising:a sitting part on which an object to be measured sits;a sensing unit mounted on the sitting part or at a portion of the object to be measured contacting the sitting part; anda ground reaction force measuring unit measuring a ground reaction force generated by a lower extremity of the object to be measured,wherein the sensing unit senses whether the object to be measured is separated from the sitting part.2. The system of claim 1 , wherein the sensing unit senses the moment that a hip or a thigh of the object to be measured is attached on the sitting part and is separated from the sitting part.3. The system of claim 1 , wherein the sensing unit is provided as a switch which is mounted at a hip or a thigh of the object to be measured and is detachable and when the hip or the thigh of the object to be measured is separated from the sitting part claim 1 , the switch is switched to an on or off state.4. The system of claim 1 , wherein the sensing unit is provided as a switch which is mounted at a hip or a thigh of the object to be measured and is detachable and provides information on timing when the hip or the thigh of the object to be measured is separated from the sitting part.5. The system of claim 1 , wherein the sensing unit includes:a first sensing element mounted at a hip or a thigh of the object to be measured; anda second sensing element mounted at a position contacting the first sensing element at the sitting part.6. The system of claim 1 , wherein the ground reaction force measuring unit includes:a first ground reaction force measuring unit provided at one lower extremity; anda second ground reaction force measuring unit ...

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Номер записи: 60
05-01-2017 дата публикации

Methods for Assessing Erythema

Номер: US20170000406A1
Автор: Neubauer Andreas, Schnidar Harald
Принадлежит:

The present invention relates to methods for an objective and quantitative erythema documentation and analysis. In particular, the invention relates to a method for assessing erythema of a subject comprising the steps of measuring the light reflectance of a skin or mucosal area of the subject, obtaining the L* value and the a* value of said measurement according to the L*a*b* color space, and calculating the erythema value according to the formula (L*−L*)×a*. 1. A computer-based method for assessing erythema of a subject comprising the steps ofmeasuring the light reflectance of a skin or mucosal or conjunctive area of the subject; andobtaining the L* value and the a* value of said measurement according to the L*a*b* color space; and {'br': None, 'sub': 'max', '(L*−L*)×a*.'}, 'calculating the erythema value according to the formula'}2. The method of for assessing the risk of a subject to develop erythema caused by irradiation comprising the steps ofmeasuring the light reflectance of a skin or mucosal area of the subject prior to irradiation,obtaining the L* value and the a* value of said measurement according to the L*a*b* color space, {'br': None, 'sub': 'max', '(L*−L*)×a*, and'}, 'calculating the baseline erythema value according to the formula'}correlating the baseline erythema value to the risk of the subject to develop erythema caused by irradiation.3. The method of for predicting the intensity of erythema that a subject develops due to irradiation comprising the steps ofmeasuring the light reflectance of a skin or mucosal area of the subject prior to irradiation,obtaining the L* value and the a* value of said measurement according to the L*a*b* color space, and {'br': None, 'sub': 'max', '(L*−L*)×a*, and'}, 'calculating the baseline erythema value according to the formula'}correlating the baseline erythema value to the intensity of erythema that the subject develops due to irradiation.4. The method of for predicting the time until a subject develops erythema ...

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Номер записи: 61
05-01-2017 дата публикации

BIOMETRICS INFORMATION REGISTRATION METHOD, BIOMETRICS AUTHENTICATION METHOD, BIOMETRICS INFORMATION REGISTRATION DEVICE AND BIOMETRICS AUTHENTICATION DEVICE

Номер: US20170000411A1
Автор: Komura Kazuhiro
Принадлежит:

A biometrics information registration method for causing a computer to execute a process including extracting vein data representing a vein image and a feature amount from an image obtained by an image obtainment unit; and making a storage unit store the vein data and the feature amount, wherein the feature amount includes a first feature amount representing a relationship between two of a plurality of segments obtained by vectorizing the vein image. 1. A biometrics information registration method for causing a computer to execute a process comprising:extracting vein data representing a vein image and a feature amount from an image obtained by an image obtainment unit; andmaking a storage unit store the vein data and the feature amount, whereinthe feature amount includes a first feature amount representing a relationship between two of a plurality of segments obtained by vectorizing the vein image.2. The biometrics information registration method according to claim 1 , whereinthe first feature amount represents a frequency distribution of angles obtained by obtaining an angle between divisional segments respectively of the two segments for each of all combinations of divisional segments respectively of the two segments.3. The biometrics information registration method according to claim 2 , whereinthe first feature amount is obtained for each of a plurality of areas when the image is divided into the plurality of areas by a first division pattern.4. The biometrics information registration method according to claim 1 , whereinthe feature amount includes a second feature amount representing a frequency distribution of directions obtained by obtaining a direction of an angle between divisional segments respectively of the two segments for each of all combinations of divisional segments respectively of the two segments.5. The biometrics information registration method according to claim 4 , whereinthe second feature amount is obtained for each of a plurality of areas ...

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Номер записи: 62
07-01-2016 дата публикации

SURGICAL VISION AND SENSOR SYSTEM

Номер: US20160000514A1
Автор: Ellman Alan
Принадлежит:

The present invention pertains to an enhanced surgical tool and display device for conducting surgical procedures which includes a wearable headgear including a frame for positioning an optical display into a field of view. A controller is attached to a portion of the frame and adapted to provide a computer generated image to an optical display. An optical display, including an active side for projecting a computer generated image, electrically communicates with the controller and is attached to the controller such that the active side is visible in a field of view. 1. An enhanced surgical tool and display device for conducting surgical procedures , comprising:a wearable headgear including a frame for positioning an optical display into a field of view;a controller attached to a portion of the frame, said controller adapted to provide a computer generated image to said optical display;the optical display including an active side adapted for projecting the computer generated image, wherein said optical display is in electrical communication with the controller, and wherein said optical display is attached to the controller such that the active side is visible in a field of view;a surgical tool including a first end for grasping the surgical tool and a second distal end for surgical contact with a region of surgically operative material; anda camera attached to the second distal end of the surgical tool and in wireless communication with the controller, wherein said camera is adapted to record and transmit visual images from a region of surgically operative material adjacent the distal end of the surgical tool to the controller, and wherein said controller is adapted to configure the visual images for projection to the active side of the optical display.2. The enhanced surgical tool and display device according to claim 1 , wherein the camera is adapted to record a video image and a still image and wherein the controller is adapted to provide an immediate projection ...

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Номер записи: 63
03-01-2019 дата публикации

METHOD AND SYSTEM FOR IMAGE PROCESSING TO DETERMINE BLOOD FLOW

Номер: US20190000554A1
Автор: Taylor Charles A.
Принадлежит:

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. 1184-. (canceled)185. A method for processing images to determine cardiovascular information , comprising the steps of:receiving image data including a plurality of coronary arteries originating from an aorta;processing the image data to generate three-dimensional shape models of the coronary arteries;simulating a blood flow for the generated three-dimensional shape models of the coronary arteries; anddetermining a fractional flow reserve (FFR) of the coronary arteries based on a blood flow simulation result, wherein in the step of simulating the blood flow, a computational fluid dynamics model is applied to the three-dimensional shape models of the coronary arteries, a lumped parameter model is combined with the computational fluid dynamics model, and a simplified coronary artery circulation model including coronary arteries, capillaries of the coronary arteries and coronary veins is used as the lumped parameter model.186. The method of claim 185 , wherein claim 185 , when simulating the blood flow claim 185 , when applying the computational fluid dynamics model to the three-dimensional shape models of the coronary arteries claim 185 , using an aorta blood pressure pattern as an inlet boundary condition.187. The method of claim 185 , wherein simulating the blood flow comprises determining lengths of centerlines of the three- ...

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Номер записи: 64
02-01-2020 дата публикации

Intraoperative Systems and Methods for Determining and Providing for Display a Virtual Image Overlaid onto a Visual Image of a Bone

Номер: US20200000523A1
Автор: Ferro Austin, Ferro Thomas D., Gill Scott, LEE Donald, Phillips Joe
Принадлежит:

Example methods and systems may be used intraoperatively to help surgeons perform accurate and replicable surgeries, such as knee arthroplasty surgeries. An example system combines real time measurement and tracking components with functionality to compile data collected by the hardware to register a bone of a patient, calculate an axis (e.g., mechanical axis) of the leg of the patient, assist a surgeon in placing cut guides, and verify a placement of an inserted prosthesis. 1. A system comprising:a measurement device to collect information of a surface of a bone of a limb of a patient, to track one or more reference points positioned on one or more bones or an anatomy of the patient, and to track one or more reference points positioned on a surgical device;one or more processors; and determining a visual model of the bone based on the collected information of the surface of the bone;', 'recognizing a position and a movement of the bone in physical space based on the tracked reference points positioned on the one or more of the bone or the anatomy of the patient and causing the visual model of the bone to reflect the position and the movement of the bone in physical space;', 'recognizing a position and a movement of the surgical device in physical space based on the tracked reference points positioned on the surgical device; and', 'providing for display a virtual image overlaid onto the visual model of the bone, wherein the virtual image includes information for assisting in placement of the surgical device at a position on the bone based on the position and the movement of the surgical device in physical space., 'data storage including instructions executable by the one or more processors for performing functions comprising2. The system of claim 1 , wherein the one or more processors perform the functions intraoperatively during surgery.3. The system of claim 1 , wherein the function of providing for display the virtual image comprises:receiving a live image of the ...

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Номер записи: 65
05-01-2017 дата публикации

Method And Device For Manufacturing And Controlling The Conformity Of A Dental Prosthesis From Parameters Obtained With A Shade Selecting Device

Номер: US20170000591A1
Автор: Guillot Julien, Rougier Frédérik
Принадлежит: TCM

A method for manufacturing and controlling the conformity of a dental prosthesis from parameters obtained intra-orally with a shade selecting device is described herein. The method includes: 1. A method for manufacturing and controlling the conformity of a dental prosthesis from parameters obtained intra-orally with a shade selecting device characterized in that it comprises the following steps:a) selecting the shade of the client tooth to be replaced or restored by the practitioner using the shade selecting device belonging to the practitioner, called DPraticien, with local storage of such data,b) transmitting these data to a computer station of the practitioner which is equipped with software for the visualization of the measurement data and possibly with software for the entry of the client's contact information and specific data, both software programs being advantageously combined,c) transmitting these data to the computer station of the dental technician,d) manufacturing the prosthesis according to the data received from the practitioner,e) controlling the data of the prosthesis manufactured by the dental technician using a shade selecting device identical to that belonging to said dental technician, called DProthésiste, calibrated in the same way as the DPraticien device of the practitioner,f) sending of the compliant prosthesis by the dental technician to the practitioner.2. The method for manufacturing and controlling the conformity of a dental prosthesis according to claim 1 , characterized in that it comprises the following steps:a) selecting the shade of the client's tooth to be replaced or restored by the practitioner using the DPraticien,b) transmitting these data to the practitioner's computer station,c) transmitting these data from the practitioner's computer station to the computer station of the dental technician,d) manufacturing the prosthesis according to the data received from the practitioner,e) controlling the data of the prosthesis ...

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Номер записи: 66
06-01-2022 дата публикации

IMAGE GENERATING APPARATUS, IMAGE GENERATING METHOD AND STORAGE MEDIUM

Номер: US20220005240A1
Автор: KUTSUNA Hideaki, SHINODA Kensuke
Принадлежит: Canon Medical Systems Corporation

An image generating apparatus according to an embodiment includes processing circuitry. The processing circuitry is configured to successively generate Magnetic Resonance (MR) images in a plurality of temporal phases by using a first reconstruction method. The processing circuitry is configured to determine a first temporal phase before MR images in all the temporal phases during a predetermined time period are generated. The processing circuitry is configured to generate an MR image in the first temporal phase determined by the determining unit, by using a second reconstruction method having a larger processing load than the first reconstruction method. 1. An image generating apparatus , comprising:processing circuitry configuredto successively generate Magnetic Resonance (MR) images in a plurality of temporal phases by using a first reconstruction method;to determine a first temporal phase before MR images in all temporal phases during a predetermined time period are generated; andto generate an MR image in the determined first temporal phase, by using a second reconstruction method having a larger processing load than the first reconstruction method.2. The image generating apparatus according to claim 1 , wherein the processing circuitry is configured to determine the first temporal phase claim 1 , on a basis of a brightness change corresponding to the temporal phases in the MR images successively generated.3. The image generating apparatus according to claim 1 , whereinthe processing circuitry is configuredto further determine a second temporal phase different from the first temporal phase, on a basis of the determined first temporal phase, andto further generates an MR image in the determined second temporal phase, by using the second reconstruction method.4. The image generating apparatus according to claim 3 , wherein the second temporal phase is a temporal phase later than the first temporal phase.5. The image generating apparatus according to claim 3 , ...

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Номер записи: 67
01-01-2015 дата публикации

Methods for the Compensation of Imaging Technique In The Processing of Radiographic Images

Номер: US20150003712A1
Автор: Daniel Steines, Philipp Lang, Rene Vargas-Voracek, Siau-Way Liew
Принадлежит: Imaging Therapeutics Inc, Imatx Inc

The present invention relates to methods and devices for analyzing x-ray images. In particular, devices, methods and algorithms are provided that allow for the accurate and reliable evaluation of bone structure and macro-anatomical parameters from x-ray images.

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Номер записи: 68
05-01-2017 дата публикации

NMR Measurements of NMR Biomarker GlycA

Номер: US20170003269A1
Автор: Dennis W. Bennett, Irina Y. Shalaurova, James D. Otvos, Justyna E. WOLAK-DINSMORE
Принадлежит: Liposcience Inc

Biomarkers and/or risk assessments identify patients having an increased risk of certain clinical disease states including, for example, CHD, type 2 diabetes, dementia, or all-cause death (ACD) using NMR signal to measure a level of “GlycA” in arbitrary units or in defined units (e.g., μmol/L) that can be determined using a defined single peak region of proton NMR spectra. The GlycA measurement can be used as an inflammation biomarker for clinical disease states . The NMR signal for GlycA can include a fitting region of signal between about 2.080 ppm and 1.845 ppm of the proton NMR spectra.

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Номер записи: 69
13-01-2022 дата публикации

SYSTEM AND METHOD OF DETERMINING AN ACCURATE ENHANCED LUND AND BROWDER CHART AND TOTAL BODY SURFACE AREA BURN SCORE

Номер: US20220008001A1
Автор: Argenta Christopher, Foderaro Greg, Paniagua Thomas, Williams Aaron
Принадлежит:

A system and method of generating an enhanced Lund and Browder chart and total body surface area burn score is described herein. In some embodiments, a plurality of images is obtained from of a patient using a camera system. The images may be taken by aligning the patient's body with pose templates presented on a display of the camera system. The non-skin portions of the images may be removed, and skin analysis performed on the skin portion to determine burn location, coverage, and depth. Further, landmarks may be detected in the images to morph and align the images with the pose templates to obtain standard poses. The plurality of images may be combined and presented in two-dimensional and three-dimensional models with labels and the total surface area burn score. 1. A method of creating an enhanced Lund and Browder chart and determining a total body surface area burn score for a patient with burns , the method comprising the steps of:obtaining, by at least one camera, a plurality of images of the patient with burns,wherein the patient is positioned based on at least one pose template presented to a user via a display associated with the at least one camera;recognizing patient body landmarks in the plurality of images;recognizing patient skin regions in the plurality of images;recognizing a background in the plurality of images;recognizing distractors in the plurality of images;recognizing burn locations on the patient in the plurality of images;combining the plurality of images to create the enhanced Lund and Browder chart; anddetermining the total body surface area burn score based at least in part on the enhanced Lund and Browder chart.2. The method of claim 1 ,wherein the enhanced Lund and Browder chart is a two-dimensional model of the patient including burns,wherein the enhanced Lund and Browder chart is two-dimensional and customized to a size and a shape of the patient,wherein the enhanced Lund and Browder chart is a combined image from the plurality of ...

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Номер записи: 70
07-01-2016 дата публикации

THERMOMETER HAVING A DIGITAL INFRARED SENSOR

Номер: US20160003690A1
Автор: Barrett John, Crawley Martin, Cronin Michael, Gerst Steven, Gross Irwin, Khachaturian Mark, Smith Michael G., Turnbull Derek
Принадлежит: Arc Devices, LTD

A non-touch thermometer that senses temperature from a digital infrared sensor is described. A digital signal representing a temperature without conversion from analog is transmitted from the digital infrared sensor received by a microprocessor and converted to body core temperature by the microprocessor. 1. A device comprising: a microprocessor;', 'a battery that is operably coupled to the microprocessor;', 'a display device that is operably coupled to the microprocessor;', 'a first digital interface that is operably coupled to the microprocessor;, 'a first circuit board including a second digital interface, the second interface being that is operably coupled to the first interface; and', 'a digital infrared sensor that is operable to receive an infrared signal, the digital infrared sensor also being operably coupled to the second interface, the digital infrared sensor having ports that provide only digital readout signals that are representative of the infrared signal that is received by the digital infrared sensor,, 'a second circuit board includingwherein the microprocessor is operable to receive from the ports of the digital infrared sensor the digital readout signals that are representative of the infrared signal and the microprocessor is operable to determine a temperature from the digital readout signals that are representative of the infrared signal, andwherein no analog-to-digital converter is operably coupled between the digital infrared sensor and the microprocessor.2. The device of wherein the display device further comprises:a green traffic light operable to indicate that the temperature is good;an amber traffic light operable to indicate that the temperature is low; anda red traffic light operable to indicate that the temperature is high.3. The device of further comprising:the digital infrared sensor having no analog sensor readout ports.4. The device of further comprising:a camera that is operably coupled to the microprocessor and providing at least ...

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Номер записи: 71
01-01-2015 дата публикации

GESTURE-BASED DERMATOLOGIC DATA COLLECTION AND PRESENTATION

Номер: US20150005640A1
Автор: Conwell William Y., Davis Bruce L., Gibson Richard F., Reed Alastair M., Rhoads Geoffrey B., Rodriguez Tony F., Sharma Ravi K., Stach John, Thagadur Shivappa Shankar
Принадлежит:

In one particular arrangement, a smartphone camera is moved by a user to capture dermatologic imagery from a variety of viewpoints. When the user thereafter holds the phone in a particular pose (e.g., with the display inclined upwardly, and with a display edge oriented substantially horizontally), the device switches to a display mode—presenting information derived from the earlier-captured dermatologic imagery. The device thus switches automatically between data collection and data presentation modes, based on pose and motion. A great variety of other features and arrangements are also detailed. 122-. (canceled)23. A method comprising the acts:sensing whether a mobile device is in a static, viewing pose;when the mobile device is sensed not to be in the static, viewing pose, collecting frames of imagery of a user; andwhen the mobile device is sensed to be in the static, viewing pose, presenting information for user review, the presented information being based, at least in part, on said collected frames of imagery;wherein the device automatically switches between data collection and data presentation modes.24. The method of in which claim 23 , when the mobile device is sensed not to be in said static claim 23 , viewing pose claim 23 , the method comprises collecting frames of imagery of the user from different viewpoints.25. The method of that further includes:sensing whether the mobile device is in motion; andwhen the mobile device is sensed to be in motion, collecting said frames of imagery of the user;wherein the device automatically switches between data collection and data presentation modes, based on pose and motion.26. The method of in which the device comprises a phone having a display and at least two cameras claim 23 , one of said cameras being on a side of the device with said display claim 23 , wherein said static claim 23 , viewing pose is a pose in which the display is upwardly inclined claim 23 , with a bottom edge of the display being substantially ...

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Номер записи: 72
01-01-2015 дата публикации

DERMOSCOPIC DATA ACQUISITION EMPLOYING DISPLAY ILLUMINATION

Номер: US20150005644A1
Автор: Rhoads Geoffrey B.
Принадлежит:

In one arrangement, a smartphone camera gathers skin imagery while controlled spectral illumination is emitted from the smartphone display. In a particular embodiment, differently colored bands move across a darkened screen to illuminate the skin from different angles as plural images are being captured. The collection of imagery from different viewing angles, with different spectral illumination, and different illumination angles, can provide imagery (including composite imagery) useful in manual or automated dermoscopic analysis. A great variety of other features and arrangements are also detailed. 129-. (canceled)30. A method employing a portable device that includes both a camera and a display screen , the method comprising the acts:presenting a first illumination from the device display screen to a subject at a first time;capturing a first image of said subject with the device camera while presenting said first illumination;presenting a second, different illumination from the device display screen to the subject at a second time; andcapturing a second image of said subject with the device camera while presenting said second illumination;wherein neither said first nor said second illumination comprises a viewfinder rendering of captured imagery.31. The method of in which:said presenting actions comprise controlling the display to present a color band of a first uniform color that moves from one side of the device display screen to a second, opposite side of the device display screen; andsaid capturing actions comprise capturing the first image with said color band at a first location, and capturing the second image with said color band at a second location.32. The method of in which said first illumination consists of light from display pixels of only a first color.33. The method of in which said first illumination consists of light from display pixels of only first and second colors.34. The method of in which the portable device includes both said camera and ...

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Номер записи: 73
04-01-2018 дата публикации

BLOOD VESSEL EXTRACTION IN TWO-DIMENSIONAL THERMOGRAPHY

Номер: US20180005085A1
Автор: Kakileti Siva Teja
Принадлежит:

What is disclosed is a system and method for isolating blood vessels in a thermographic image of a patient's breast or any other muscular region of the body. A thermographic image of a patient is received. A temperature-based analysis is performed on the image to detect vessel pixels. An intensity-based method analysis is performed on the image. A shape-based analysis is also performed to detect pixels of vessel-like structures. Candidate pixels which satisfy one or more of intensity-based or temperature-based or shaped-based criterion are identified. A constraint of local maximallity is thereafter imposed on each candidate pixel that satisfies both criterion to eliminate spurious non-vessel pixels. Candidate pixels which satisfy both criterion are then marked with a different color such that the vessel structures in the breast tissue can be visually differentiated. The vessel structures are provided to a classifier system which classifies the tissue in the thermal image as malignant and non-malignant otherwise, based on a tortuosity of the vessel structures. 1. A method for isolating blood vessels in a thermographic image of a patient , the method comprising:receiving a thermographic image of a patient;performing blood vessel detection on the received image to detect pixels of vessel-like structures;identifying pixels associated with vessel structures in the thermal image; anddrawing lines on the thermal image to represent identified blood vessel structures.2. A method of claim 1 , wherein the blood vessel structures are detected based on temperature of the pixels claim 1 , intensity of pixels or a shape-based method to detect a patch of pixels that are vessel-like structures claim 1 , wherein said method further comprisesidentifying candidate pixels associated with vessel structures in the breast tissue in the thermal image that satisfy one or all of the temperature-based, intensity-based and shaped-based methods; andremoving non-vessel pixels from the identified ...

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Номер записи: 74
02-01-2020 дата публикации

INTEGRATIVE PREDICTION OF A COGNITIVE EVOLUTION OF A SUBJECT

Номер: US20200005095A1
Автор: KOBER TOBIAS, POPP JULIUS, RICHIARDI JONAS
Принадлежит:

System and method for automatically predicting an evolution of a cognitive score for a subject by classifying a cognitive data set for said subject into either a first class or a second class, the method comprising: 1. A machine learning method for predicting an evolution of a cognitive score for a subject by automatically classifying a cognitive dataset for said subject into either a first class associated with a first evolution of said cognitive score or a second class associated with a second evolution of said cognitive score , said cognitive set of data comprising biomarker cognitive data including normalized volumetric information and CDR sum-of-boxes (CDRSoB) neuropsychological score , the method comprising:{'b': '1', 'claim-text': acquiring brain structural images from said group of subjects and extracting for each subject volumetric information for a set of predefined brain regions;', 'for each subject, normalizing said volumetric information by the total intracranial volume of said subject in order to obtain said normalized volumetric information;', 'acquiring for each subject a first CDRSoB neuropsychological score;, 'a) determining the cognitive set of data for each subject of a group of subjects by acquiring biomarker cognitive data for the subject, wherein said biomarker cognitive data have been established or measured for said subject at a first time period T, said acquisition of biomarker cognitive data comprising{'b': 2', '1, 'b) acquiring for each subject a second CDRSoB neuropsychological score, wherein said second CDRSoB neuropsychological score has been measured for the subject at a second time period T temporally situated after T;'}c) automatically classifying each subject in function of the value of the second CDRSoB neuropsychological score compared to the value of the first CDRSoB neuropsychological score either into said first class or into said second class;d) grouping the predefined brain regions within atrophy networks, and determining ...

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Номер записи: 75
07-01-2021 дата публикации

SYSTEMS AND METHODS OF MEASURING THE BODY BASED ON IMAGE ANALYSIS

Номер: US20210004957A1
Автор: AALAMIFAR Fereshteh
Принадлежит: PediaMetrix Inc.

The present disclosure is generally related to systems and methods that can be implemented in a mobile application to allow users, such as parents and care providers, to measure and monitor, for example, a patient's body including an infant's head shape, at the point of care. The point of care can be, for instance, the home environment, a doctor's office, or a hospital setting. After acquiring 2D and/or 3D images of the body part, parameters reflecting potential deformity can be calculated. If abnormal measurements are determined, the user can be guided through therapeutic options to improve the condition. Based on the severity of the condition, different recommendations can be provided. Moreover, longitudinal monitoring and evaluation of the parameters can be performed. Monitoring of the normal child development can also be performed through longitudinal determination of parameters and comparison to normative values. Data can be shared with clinician's office. 1. A system , comprising:an image sensor configured to acquire one or more images of a head of a patient, the head of the patient having a cranial shape;a display; and receive the one or more images of the head of the patient,', 'determine a cranial contour based on the received one or more images of the head of the patient,', 'calculate at least one cranial parameter based on the determined cranial contour, the at least one cranial parameter being one selected from a group including cephalic index and cranial vault asymmetry index,', 'compare the at least one cranial parameter to a pre-determined threshold of the at least one cranial parameter, and', 'determine, based on the comparison, an abnormality of the cranial shape of the head of the patient., 'processing circuitry configured to'}2. The system according to claim 1 , wherein the processing circuitry is further configured to claim 1 , during acquisition of the one or more images of the head of the patient by the image sensor claim 1 , overlay an ...

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Номер записи: 76
07-01-2021 дата публикации

DISPLAY OF MEDICAL IMAGE DATA

Номер: US20210004960A1
Автор: GROTH ALEXANDRA, SAALBACH Axel, WEESE Rolf Jürgen
Принадлежит:

A system and method are provided for display of medical image data, with the display of the medical image data being determined on the basis of schematic image data of a schematic representation of an anatomical structure. The schematic representation may provide a particular view of the anatomical structure. The type of anatomical structure and the view of the anatomical structure provided by the schematic representation may be determined based on one or more image features in the schematic image data. The view may be characterized as a geometrically-defined perspective at which the anatomical structure is shown in the schematic representation. An output image may be generated showing the anatomical structure in the medical image data in accordance with said determined geometrically-defined perspective. A user may thus be provided with a display of medical image data which is easier to interpret having considered said schematic representation. 1. A system for display of medical image data , comprising:an input interface for accessing first image data comprising a schematic representation of an anatomical structure, the schematic representation providing a particular view of the anatomical structure;a memory comprising instruction data representing a set of instructions; analyze the first image data to determine i) a type of anatomical structure and ii) the view of the anatomical structure provided by the schematic representation, based on one or more image features in the first image data, the view being characterized as a geometrically-defined perspective at which the anatomical structure is shown in the schematic representation;', 'via the input interface, access second image data being volumetric image data acquired of a patient, the second image data comprising the type of anatomical structure; and', 'generate an output image showing the anatomical structure in the second image data in accordance with said geometrically-defined perspective., 'a processor ...

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Номер записи: 77
02-01-2020 дата публикации

HYPERSPECTRAL IMAGING SENSOR

Номер: US20200005455A1
Автор: Alshurafa Nabil I., Cossairt Oliver Strider, Katsaggelos Aggelos K.
Принадлежит:

Systems, methods, and computer readable media for hyperspectral imaging are provided. An example hyperspectral imaging sensor system to identify item composition includes an imager to capture hyperspectral imaging data of one or more items with respect to a target. The example includes a sensor to be positioned with respect to the target to trigger capture of the image data by the imager based on a characteristic of the target. The example includes a processor to prepare the captured imaging data for analysis to at least: identify the one or more items; determine composition of the one or more items; calculate an energy intake associated with the one or more items; and classify the target based on the energy intake. 1. A hyperspectral imaging sensor system to identify item composition , the system comprising:an imager to capture hyperspectral imaging data of one or more items with respect to a target;a sensor to be positioned with respect to the target to trigger capture of the image data by the imager based on a characteristic of the target; and identify the one or more items;', 'determine composition of the one or more items;', 'calculate an energy intake associated with the one or more items; and', 'classify the target based on the energy intake., 'a processor to prepare the captured imaging data for analysis to at least2. The system of claim 1 , wherein the one or more items include food items.3. The system of claim 1 , wherein the characteristic of the target includes at least one of chewing or swallowing.4. The system of claim 1 , wherein the sensor includes at least one of a proximity sensor claim 1 , an inertial measurement unit claim 1 , or a light sensor.5. The system of claim 1 , wherein the imager is to capture both hyperspectral imaging data and red-green-blue imaging data to be fused into combined imaging data for analysis.6. The system of claim 1 , wherein the energy intake is based on caloric content of the one or more items to be determined by ...

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Номер записи: 78
03-01-2019 дата публикации

APPARATUS HAVING A DIGITAL INFRARED SENSOR

Номер: US20190005642A1
Автор: Barrett John, Crawley Martin, Cronin Michael, Gerst Steven, Gross Irwin, Khachaturian Mark, Smith Michael G., Turnbull Derek
Принадлежит: Arc Devices, LTD

An apparatus that senses temperature from a digital infrared sensor is described. A digital signal representing a temperature without conversion from analog is transmitted from the digital infrared sensor received by a microprocessor and converted to body core temperature by the microprocessor. 1. A device comprising: a microprocessor;', 'a battery that is operably coupled to the microprocessor;', 'a display device that is operably coupled to the microprocessor;', 'a first digital interface that is operably coupled to the microprocessor;, 'a first circuit board including a second digital interface, the second digital interface being that is operably coupled to the first digital interface; and', 'a digital infrared sensor that is operable to receive an infrared signal, the digital infrared sensor also being operably coupled to the second digital interface, the digital infrared sensor having ports that provide digital readout signals that are representative of the infrared signal that is received by the digital infrared sensor,, 'a second circuit board includingwherein the microprocessor is operable to receive from the ports of the digital infrared sensor the digital readout signals that are representative of the infrared signal and the microprocessor is operable to determine a temperature from the digital readout signals that are representative of the infrared signal, andwherein no analog-to-digital converter is operably coupled between the digital infrared sensor and the microprocessor.2. The device of wherein the display device further comprises:a green traffic light operable to indicate that the temperature is good;an amber traffic light operable to indicate that the temperature is low; anda red traffic light operable to indicate that the temperature is high.3. The device of further comprising:the digital infrared sensor having no analog sensor readout ports.4. The device of further comprising:a camera that is operably coupled to the microprocessor and providing ...

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Номер записи: 79
12-01-2017 дата публикации

METHOD OF ESTIMATING BLOOD PRESSURE BASED ON IMAGE

Номер: US20170007137A1
Автор: HONG Kwang-Seok, LEE Ho Sung, PARK JinSoo
Принадлежит: Research and Business Foundation SUNGKYUNKWAN UNIVERSITY

A method of estimating a blood pressure based on an image is provided. The method includes obtaining, by camera, an image including a skin of a user, determining, by a computer device, a skin region, in which at least one portion of the skin is displayed, from the image, and storing a mean value of color data of a designated color model for each of two target regions which have different positions in the skin region from each other, estimating, by the computer device, a pulse-wave transit time (PTT) based on a pulse wave signal determined based on a change in the mean value of the color data for each of the two target regions, and estimating, by the computer device, the blood pressure using the PTT. 1. A method of estimating a blood pressure based on an image , comprising:obtaining, by camera, an image including a skin of a user;determining, by a computer device, a skin region, in which at least one portion of the skin is displayed, from the image, and storing a mean value of color data of a designated color model for each of two target regions which have different positions in the skin region from each other;estimating, by the computer device, a pulse-wave transit time (PTT) based on a pulse wave signal determined based on a change in the mean value of the color data for each of the two target regions; andestimating, by the computer device, the blood pressure using the PTT.2. The method of claim 1 , wherein the storing of the mean value comprises:dividing the skin region in the image into two and storing the mean value of the color data for the two target regions; orextracting skin regions from images obtained by two cameras respectively and storing the mean value of the color data by determining the extracted two skin regions as the two target.3. The method of claim 1 , wherein the storing of the mean value comprises:setting, by the computer device, the two target regions by dividing the image; andgenerating a change in the mean value of the color data for each of ...

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Номер записи: 80
12-01-2017 дата публикации

MICROWAVE TOMOGRAPHY APPARATUS AND METHOD THEREOF

Номер: US20170007150A1
Автор: CHOI Hyung Do, JEON Soon Ik, KIM Bo Ra, KIM Hyuk Je, KIM Jang Yeol, LEE Jong Moon, Lee Kwang Jae, SON Seong Ho
Принадлежит: Electronics and Telecommunications Research Institute

According to the exemplary embodiment of the present invention, a microwave tomography apparatus is an apparatus which measures microwave tomograph of a subject which is inserted into a medium container including: a plurality of antennas which is located in the medium container and transmits and receives an electromagnetic wave; a plurality of transceivers which, when a radio wave signal transmitted from one of the plurality of antennas is simultaneously received by the remaining antennas of the plurality of antennas, measures intensity and phase information of the radio wave signal received from the remaining antennas; and a controller which generates an image using the values measured by the plurality of transceivers. 1. A microwave tomography apparatus in a system which measures microwave tomograph of a subject which is inserted into a medium container , the apparatus comprising:a plurality of antennas which is located in the medium container and transmits and receives an electromagnetic wave;a plurality of transceivers which, when a radio wave signal transmitted from one of the plurality of antennas is simultaneously received by the remaining antennas of the plurality of antennas, measures intensity and phase information of the radio wave signal received from the remaining antennas; anda controller which generates an image using the values measured by the plurality of transceivers.2. The apparatus of claim 1 , wherein the controller controls to perform primary measurement which measures the intensity and phase information of the radio wave signal in a state when the subject is not present in the medium container and controls to perform secondary measurement of the intensity and phase information of the radio wave signal in a state when the measuring subject is inserted into the medium container.3. The apparatus of claim 1 , wherein the plurality of transceivers is connected to the plurality of antennas by one to one correspondence.4. The apparatus of claim 1 , ...

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Номер записи: 81
12-01-2017 дата публикации

CANCER DETECTOR USING DEEP OPTICAL SCANNING

Номер: US20170007187A1
Автор: Breneisen Michael, Murray John, Schneider Kenneth S., Strom Joel A.
Принадлежит: Telebyte, Inc.

A device and a system, based upon Deep Optical Scanning (DEOS), for the detection of certain cancers such as breast cancer and the determination of their response to therapy. DEOS is based upon the nonlinear optical interaction of incident laser generated light with tissue. The cancers may either be subsurface or on the surface. The system includes hardware and software components that form subsystems including: an Optical Electronic Subsystem, a Digitization Subsystem, a Parameter Computation Subsystem, an Archive, an Artificial Intelligence Subsystem, and a Presentation Subsystem. The device can be made portable and is non-invasive in its application to a patient. The system can be integrated into a hybrid architecture with other imaging techniques used for the detection of cancers. 1. A computer-implemented method for cancer detection using deep optical scanning , comprising:sequentially illuminating a target area of a patient's body using a plurality of optical transmissions, wherein each transmission has a different wavelength; andprocessing reflected optical signals from the target area using a nonlinear optics (NLO) technique, wherein the processing produces digital representations of the reflected optical signals; and producing an initial decision by a neural network that uses the digital representations as input, and', 'refining the initial decision by an expert system that executes a rule based logical reasoning algorithm to determine, based on at least one data source, whether the initial decision should be changed., 'generating an output decision as to whether cancer is detected in the target area, wherein the output decision is generated by2. The method of claim 1 , wherein the NLO technique is second harmonic generation claim 1 , wherein the digital representations are formed by calculating an energy spectral density (ESD) for each transmission claim 1 , and wherein each ESD is a time integral of a power spectral density of reflected optical signals.3. ...

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Номер записи: 82
04-01-2018 дата публикации

EXERCISE EVALUATING APPARATUS

Номер: US20180007277A1
Автор: AIBARA Takehiro
Принадлежит:

An exercise evaluating apparatus including: a processor; and a recording medium which records a program executed by the processor to perform processing, wherein, the processor is configured to perform: generating a combined image from a plurality of images successively imaging a moving subject, the combined image being an image in which a change in motion of the subject according to a time series can be understood; obtaining motion data corresponding to motion of the subject output from a motion sensor attached to the subject; and controlling the display to display the combined image and the motion data in a state corresponding a time series of the plurality of images used in generating the combined image with a time series of the obtained motion data. 1. An exercise evaluating apparatus comprising:a processor; anda recording medium which records a program executed by the processor to perform processing, generating a combined image from a plurality of images successively imaging a moving subject, the combined image being an image in which a change in motion of the subject according to a time series can be understood;', 'obtaining motion data corresponding to motion of the subject output from a motion sensor attached to the subject; and', 'controlling a display to display the combined image and the motion data in a state corresponding a time series of the plurality of images used in generating the combined image with a time series of the obtained motion data., 'wherein, the processor is configured to perform2. The exercise evaluating apparatus according to claim 1 , wherein claim 1 , in the controlling of the display claim 1 , when the motion data for a predetermined term is displayed on the display claim 1 , the combined image and the motion data are displayed on the display so that the time series of the plurality of images used in generating the combined image imaged for the predetermined term is corresponded with the time series of the motion data.3. The exercise ...

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Номер записи: 83
14-01-2016 дата публикации

IMAGE DETECTION SYSTEM FOR DIAGNOSING PHYSIOLOGIC STATUS OF ORGAN HAVING FLUORESCENT MATTER

Номер: US20160007855A1
Автор: Liu Tzu-Ming
Принадлежит: NATIONAL TAIWAN UNIVERSITY

An image detection system for diagnosing a metabolic function and physiological status of a tissue or an organ having a fluorescent matter is provided. The image detection system includes a source emitting exciting light, a scan unit converting the exciting light into a scan of the exciting light, a light-guiding unit including an object lens, a splitter unit, and a detection unit. The splitter unit directs the scan of the exciting light to enter a tissue having a fluorescent matter such that the fluorescent matter in the tissue is excited by the scan of the exciting light and emits fluorescence light, whereby a layer of the tissue is scanned by the scan of the exciting light. The splitter unit directs the fluorescence light emitted from the tissue to the detection unit for processing so as to generate a fluorescent image of the layer of the tissue. 1. An image detection system , comprising:a source that emits exciting light;a scan unit that converts the exciting light into a scan of the exciting light;a light-guiding unit including an object lens, the object lens guiding the scan of the exciting light into a tissue having a fluorescent matter such that the fluorescent matter in the tissue is excited by the scan of the exciting light and emits fluorescence light, whereby a layer of the tissue is scanned by the scan of the exciting light;a detection unit that detects and processes the fluorescence light emitted by the tissue, so as to generate a fluorescent image of the layer of the tissue; anda splitter unit that directs the scan of the exciting light to the object lens so as to enter the tissue, and further directs the fluorescence light emitted by the tissue to the detection unit such that the fluorescent image of the layer of the tissue is generated by the detection unit.2. The image detection system of claim 1 , wherein the detection unit comprises a filter claim 1 , a photomultiplier and a processor claim 1 , the filter is used to allow the fluorescence light ...

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Номер записи: 84
14-01-2016 дата публикации

IMAGING SYSTEM WITH HYPERSPECTRAL CAMERA GUIDED PROBE

Номер: US20160007858A1
Автор: Hendriks Bernardus Hendrikus Wilhelmus, Lucassen Gerhardus Eilhelmus, Mueller Manfred, Pully Vishnu Vardhan, REICH CHRISTIAN, Schleipen Johannes Joseph Hubertina Barbara
Принадлежит:

A medical imaging system for identifying a target structure (TS), e.g. a tumor, in a biological tissue. A hyperspectral camera system is used for imaging a surface area (A) of the tissue (BT), e.g. with a limited spectral resolution, but enough to allow identification of suspicious areas where the target structure (TS) may be, e.g. such areas can be visually indicated on a display to the operator. A probe (PR), e.g. an optical surface probe, is used to provide probe measurement of a smaller surface area (A) of the tissue, but with more information indicative of the target structure. The probe is selected to provide a higher specificity with respect to identification of the target structure than the hyperspectral camera (HSC). The hyperspectral processing algorithm (PP) is then calibrated based on probe measurement data performed within the suspicious areas, thus providing a calibrated hyperspectral processing algorithm resulting in images with an enhanced sensitivity to identify the target structure. Only few probe measurements are required to significantly improve the resulting image, thereby providing a reliable and fast target structure (TS) identification. 1. A medical imaging system arranged to identify a target structure in an associated biological tissue , the system comprisinga hyperspectral camera system arranged to provide a hyperspectral image covering a first surface area of the biological tissue, wherein pixels of the hyperspectral image contains information at different light wavelength bands,a probe arranged to provide a probe measurement of a second surface area of the biological tissue with information indicative of the target structure, and to generate probe measurement data accordingly, wherein the second surface area is smaller than the first surface area, and wherein the probe is selected to provide a higher specificity with respect to identification of the target structure than the hyperspectral camera system, anda processor functionally ...

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Номер записи: 85
14-01-2016 дата публикации

Coherent Frequency-Domain Microwave-Induced ThermoAcoustic Imaging

Номер: US20160007859A1
Автор: HAO Nan, Mohammad Amin Arbabian
Принадлежит: Leland Stanford Junior University

A thermoacoustic imaging device is provided having a transmitter configured to provide an electromagnetic transmit signal (e.g. a continuous sinusoidal signal) to an object being imaged. The transmit signal is a modulated continuous-wave signal based on a carrier frequency signal f c modulated at a modulation frequency at or near f m . The detector is further configured to receive an acoustic signal from the object being imaged, and is responsive to acoustic frequencies at or near 2f m . A non-linear thermoacoustic effect in the object being imaged generates the acoustic signal from the object being imaged. Spectroscopic maps could be generated and imaged object could be analyzed. The device enhances signal-to-noise ratio of the reconstructed image and reduces the requirement of peak power in thermoacoustic imaging systems. In addition, the generated pressure of the imaged object is separated from microwave leakage and feedthrough in frequency through the nonlinear thermoacoustic effect.

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Номер записи: 86
14-01-2016 дата публикации

BLOOD FLOW INDEX CALCULATING METHOD, BLOOD FLOW INDEX CALCULATING APPARATUS, AND RECORDING MEDIUM

Номер: US20160007865A1
Автор: INOMATA Akihiro, Sakata Masato, Sekiguchi Hidenori, Uchida Daisuke
Принадлежит:

A blood flow index calculating method includes: obtaining, by a camera, an image capturing a first site of a living body and a second site of the living body; extracting an area of the first site of the living body and an area of the second site of the living body, by a processor; detecting a pulse wave pattern of the first site of the living body from the area of the first site of the living body and detecting a pulse wave pattern of the second site of the living body from the area of the second site of the living body, by the processor; first calculating a delay amount from the pulse wave pattern of the first site and the pulse wave pattern of the second site, by the processor; and second calculating an index related to blood flow by using the delay amount, by the processor. 1. A blood flow index calculating method comprising:obtaining, by a camera, an image capturing a first site of a living body and a second site of the living body, the first site being a part of the living body of a subject, and the second site being a site different from the first site;extracting an area of the first site of the living body and an area of the second site of the living body, the areas being included in the image, by a processor;detecting a pulse wave pattern of the first site of the living body from the area of the first site of the living body and detecting a pulse wave pattern of the second site of the living body from the area of the second site of the living body, by the processor;first calculating a delay amount from the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second site of the living body, by the processor; andsecond calculating an index related to blood flow by using the delay amount, by the processor.2. The blood flow index calculating method according to claim 1 , further including third calculating a similarity between the pulse wave pattern of the first site of the living body and the pulse wave pattern of the second ...

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Номер записи: 87
14-01-2016 дата публикации

APPARATUS AND METHOD FOR DETERMINING A RESPIRATION VOLUME SIGNAL FROM IMAGE DATA

Номер: US20160007883A1
Автор: ROCQUE Mukul Julius, Shan Caifeng
Принадлежит:

The present invention relates to apparatus () for determining a respiration volume signal from a subject (), comprising a processing unit () for receiving image data () detected from a field of view () and for determining an alternating signal (S)including vital sign information (R) of the subject () from the image data (), an analysis unit () for determining at least one characteristic parameter (A) corresponding to a respiration parameter of the subject () on the basis of the alternating signal (S), a calibration unit () for determining a calibration value (V V) on the basis of a breathing volume measured during inhale and/or exhale of the subject () by means of an airflow or an air volume measurement, and a calculation unit () for calculating the respiration volume of the subject () on the basis of the calibration value (V V) and the at least one characteristic parameter (A). 1. An apparatus for determining a respiration volume signal from a subject , comprising:a processing unit for receiving image data detected from a field of view and for determining a plurality of alternating signals including vital sign information of the subject from different areas of the filed of view from the image data,an analysis unit for determining at least one characteristic parameter corresponding to a respiration parameter of the subject on the basis of the plurality of alternating signals,a calibration unit for determining a calibration value on the basis of a breathing volume measured during inhale and/or exhale of the subject by means of an airflow or an air volume measurement, anda calculation unit for calculating the respiration volume of the subject on the basis of the calibration value and the at least one characteristic parameter wherein the plurality of alternating signals are weighted by a weight factor.2. The apparatus as claimed in claim 1 , wherein the processing unit is connected to an image detection unit for providing the image data from the field of view.3. The ...

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Номер записи: 88
14-01-2016 дата публикации

Surgery assistance apparatus and method, and non-transitory recording medium having stored therein surgery assistance program

Номер: US20160008085A1
Автор: Yoshinori Itai
Принадлежит: Fujifilm Corp

A surgery assistance apparatus includes an organ region extraction unit that extracts a tubular-organ region from a three-dimensional image obtained by imaging a tubular-organ and a blood vessel dominating the tubular-organ, a blood vessel region extraction unit that extracts a blood vessel region dominating the tubular-organ from the three-dimensional image, a branching structure extraction unit that extracts a branching structure of the blood vessel from the extracted blood vessel region, and a dominated region identification unit that identifies, with respect to an arbitrary partial blood vessel corresponding to an upper edge branching at least once to reach an edge including a terminal-end of the extracted branching structure, a dominated region in the tubular-organ region that is dominated by the arbitrary partial blood vessel by using positional relationships between a plurality of terminal end points present after the edge of the arbitrary partial blood vessel branches last and the tubular-organ region.

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Номер записи: 89
14-01-2016 дата публикации

Systems and Methods for Planning Hair Transplantation

Номер: US20160008086A1
Автор: Franklin Timothy Mcarthur, Gabriele Zingaretti, HUI Zhang
Принадлежит: Restoration Robotics Inc

Systems and methods for creating a treatment plan for cosmetic procedures, for example, a hair transplantation procedure, are provided. The treatment plan allows user to provide input on a proposed hair element using a free-hand drawing in a two-dimensional plane, and for the proposed hair element to be generated and displayed on a three-dimensional model of a body surface. Various techniques and methods described in the application provide for improved planning of a natural looking hair.

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Номер записи: 90
14-01-2021 дата публикации

Systems and Methods for Generating Biomarkers Based on Multivariate MRI and Multimodality Classifiers for Disorder Diagnosis

Номер: US20210007603A1
Автор: Huddleston Daniel, Mahmoudi Babak
Принадлежит:

In some embodiments, the systems and methods of the disclosure can efficiently and accurately classify neurodegenerative disorder(s) and/or movement disorder(s) of a subject (e.g., a patient) using at least quantitative features associated with one or more regions of interest determined from one or more sets of image data of the subjects brain. The method may include processing one or more sets of MRI image data of the subjects brain to extract one or more quantitative features for one or more regions. The one or more quantitative features may include a first quantitative and a second quantitative feature. The method may further include classifying at least the one or more quantitative features into one or more classes associated with neurodegenerative dementia disorder, neurodegenerative movement disorder, non-neurodegenerative movement disorder and/or heathy control. The method may include generating a report including a classification of at least the one or more quantitative features. 1. A computer-implemented method for classifying neurodegenerative disorder(s) and/or movement disorder(s) of a subject , the method comprising:receiving subject data of a subject, the subject data including one or more sets of MRI image data of a brain of the subject;processing one or more sets of MRI image data to extract one or more quantitative features for one or more regions, the one or more quantitative features for the one or more regions includes a first quantitative feature for the one or more regions and a second quantitative feature for the one or more regions;classifying at least the one or more quantitative features for the one or more regions into one or more classes associated with neurodegenerative dementia disorder, neurodegenerative movement disorder, non-neurodegenerative movement disorder, and/or heathy control; andgenerating a report including a classification of at least the one or more quantitative features.2. The method according to claim 1 , wherein the one ...

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Номер записи: 91
14-01-2021 дата публикации

METHOD OF AND IMAGING SYSTEM FOR CLINICAL SIGN DETECTION

Номер: US20210007606A1
Автор: Chen Shann-Ching, Chou Cheng-Fu, Su Tung-Hung
Принадлежит:

The disclosure provides a method of and an imaging system for clinical sign detection. The method uses an imaging system having an RGB image sensor and the processing device disclosed herein. An image of a patient or examinee is captured by the RGB image sensor to generate an RGB image. Clinical signs of the patient or examinee are detected by the processing device based on the RGB images. 1. A method of clinical sign detection , applicable to an imaging system having an RGB image sensor and a processing device , comprising:capturing an image of a patient or examinee by the RGB image sensor to generate an RGB image; anddetecting clinical signs of the patient or examinee based on the RGB image by the processing device.2. The method according to claim 1 , wherein after the step of generating the RGB image claim 1 , the method further comprises:setting the RGB image in each RGB channel as inputs for detecting the clinical signs of the patient or examinee.3. The method according to claim 1 , wherein after the step of generating the RGB image claim 1 , the method further comprises:extracting melanin components and hemoglobin components from the RGB image to generate a melanin image and a hemoglobin image;setting the RGB image in each RGB channel, the melanin image, and the hemoglobin image as inputs for detecting the clinical signs of the patient or examinee.4. The method according to claim 1 , wherein the step of detecting the clinical signs of the patient or examinee based on the RGB image comprises:locating at least one key region of interest (ROI) from the RGB image based on a deep learning neural network based (DNN-based) localization algorithm;determining at least one abnormal ROI from the RGB image based on a DNN-based classification algorithm; andidentifying the clinical signs based on at least one of the key ROI and the abnormal ROI.5. The method according to further comprises:feeding the at least one key ROI to a machine learning classifier to produce a ...

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Номер записи: 92
14-01-2021 дата публикации

Method and Apparatus for Non-Invasive Hemoglobin Level Prediction

Номер: US20210007648A1
Автор: Ahamed Sheikh Iqbal, Hasan Md Kamrul, Love Richard R.
Принадлежит:

An image-based hemoglobin estimation tool for measuring hemoglobin can be embedded in hand held devices such as smartphones, and similar known and to be developed technology. The hand-held device acquires video data of a finger illuminated from the dorsal surface by a first near infrared light responsive to hemoglobin and a second near infrared light near responsive to plasma. The acquired video is segmented into frames and processed to produce a Photoplethysmography (PPG) waveform. The features of the PPG waveform can then be identified, and the waveform and corresponding features evaluated by a predictive hemoglobin model. The predictive hemoglobin model can be provided at a remote computer, enabling non-invasive hemoglobin analysis from point of care locations. Near infrared lights of 850 nm and 1070 nm are particularly effective in the process. 1. A method for non-invasively blood hemoglobin levels , comprising the following steps:acquiring a time-based series of images of the finger ventral pad-tip illuminated from the dorsal side of the finger with a near infrared light responsive to blood hemoglobin, and white light;acquiring a second time-based series of images of the finger ventral pad-tip illuminated from the dorsal side of the finger with a near infrared light responsive to blood plasma, and white light;dividing images in each of the first and second time-based series into groups of blocks;generating time series signals from each block;identifying at least one Photoplethysmography (PPG) cycle from each of the time series signals, including a systolic peak and a diastolic peak; andprocessing the PPG cycles to determine blood hemoglobin levels.2. The method of claim 1 , wherein the step of acquiring a time-based series of images comprises acquiring a first and a second video claim 1 , and wherein the near infrared light responsive to blood hemoglobin has a wavelength of between 800 and 950 nm and the near infrared light responsive to plasma has a wavelength ...

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Номер записи: 93
11-01-2018 дата публикации

System of joint brain tumor and cortex reconstruction

Номер: US20180008187A1
Автор: Bi Song, Chen-Rui Chou, Ming-Chang Liu
Принадлежит: Sony Corp

System for performing fully automatic brain tumor and tumor-aware cortex reconstructions upon receiving multi-modal MRI data (T1, T1c, T2, T2-Flair). The system outputs imaging which delineates distinctions between tumors (including tumor edema, and tumor active core), from white matter and gray matter surfaces. In cases where existing MRI model data is insufficient then the model is trained on-the-fly for tumor segmentation and classification. A tumor-aware cortex segmentation that is adaptive to the presence of the tumor is performed using labels, from which the system reconstructs and visualizes both tumor and cortical surfaces for diagnostic and surgical guidance. The technology has been validated using a publicly-available challenge dataset.

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Номер записи: 94
11-01-2018 дата публикации

MEASURING AND MONITORING SKIN FEATURE COLORS, FORM AND SIZE

Номер: US20180008188A1
Автор: ADIRI Yonatan, Mendelowitz Shachar, Omer Ido, SALOMON Roee
Принадлежит: OWNHEALTH LTD.

Kits, diagnostic systems and methods are provided, which measure the distribution of colors of skin features by comparison to calibrated colors which are co-imaged with the skin feature. The colors on the calibration template (calibrator) are selected to represent the expected range of feature colors under various illumination and capturing conditions. The calibrator may also comprise features with different forms and size for calibrating geometric parameters of the skin features in the captured images. Measurements may be enhanced by monitoring over time changes in the distribution of colors, by measuring two and three dimensional geometrical parameters of the skin feature and by associating the data with medical diagnostic parameters. Thus, simple means for skin diagnosis and monitoring are provided which simplify and improve current dermatologic diagnostic procedures. 126-. (canceled)27. A method comprising:attaching a calibrator comprising a plurality of color areas onto a skin area next to a skin feature;capturing at least one image of the skin area, which includes both the skin feature and at least a part of the calibrator;deriving, from the at least one captured image, an image normalization function from a comparison between captured calibrator colors and the selected calibrator colors; andapplying the image normalization function to the captured skin feature to yield normalized colors of the skin feature.28. The method of claim 27 , further comprising associating at least one color parameter of the skin feature with medical diagnostic criteria claim 27 , and monitoring the at least one color parameters over time in periodically captured images.29. The method of claim 27 , further comprising capturing a plurality of images of the skin feature and deriving a three-dimensional characterization of the skin feature therefrom.30. The method of claim 27 , further comprising deriving from the at least one captured image at least one geometric parameter of the skin ...

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Номер записи: 95
10-01-2019 дата публикации

SYSTEMS AND METHODS FOR DYNAMICALLY IDENTIFYING A PATIENT SUPPORT SURFACE AND PATIENT MONITORING

Номер: US20190008416A1
Автор: Chapman Kenneth, Clark Matt, del Carpio Derek
Принадлежит:

Various patient monitoring systems can include a sensor configured to collect three dimensional information. The systems can identify a location of a patient support surface based on the three dimensional information. The systems can set a two dimensional planar threshold based on the patient support surface. The systems can identify a patient location above the patient support surface based on the three dimensional information and compare the patient location to the two dimensional planar threshold. Exceeding the threshold can be indicative of a high risk of a patient fall. An alert can be generated based on the threshold being exceeded. The systems can repeat the identification of the patient support surface location and the setting of the threshold to account for changes in the patient area. 132-. (canceled)33. A patient monitoring system for monitoring a patient area , the system comprising:a sensor configured to output a plurality of frames, the plurality of frames containing three dimensional information of the patient area, wherein the three dimensional information comprises grid positions of a plurality of pixels represented by coordinates along X- and Y-axes and depth of each pixel relative to a floor along a Z-axis; andcontrol circuitry configured to:receive the three dimensional information of the plurality of frames;identify a location of a patient support surface by segmenting the three dimensional information into candidate areas and grouping one or more planar surfaces in the candidate areas based on pixel depth;set at least one threshold above the location of the patient support surface on the Z-axis;identify one or more patient locations based on pixels that are above a depth of the patient support surface and within the location of the patient support surface;compare the one or more patient locations to the at least one threshold; andgenerate an output for display on a user interface based on the one or more patient locations traversing the at ...

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Номер записи: 96
10-01-2019 дата публикации

SYSTEM AND METHODS FOR MANAGING BLOOD LOSS OF A PATIENT

Номер: US20190008427A1
Автор: MILLER Kevin J, Satish Siddarth, Zandifar Ali
Принадлежит:

One variation of the method for managing blood loss of a patient includes: receiving an image of a physical sample; extracting a feature from an area of the image corresponding to the physical sample; estimating a blood volume indicator of the physical sample according to the extracted feature; estimating a patient blood loss based on the blood volume indicator; estimating a euvolemic patient hematocrit based on an estimated patient blood volume and the estimated patient blood loss; receiving a measured patient hematocrit; and generating a volemic status indicator based on a comparison between the measured patient hematocrit and the estimated euvolemic patient hematocrit. 117-. (canceled)18. A method for managing blood loss of a patient , comprising:tracking a quantity of a fluid administered to the patient intravenously;receiving an image of a physical sample;extracting a feature from an area of the image correlated with the physical sample;estimating a red blood cell content of the physical sample based on the extracted feature;estimating an extracorporeal blood content of the physical sample based on the estimated red blood cell content of the physical sample; andestimating a hematocrit of the patient based on a previous hematocrit of the patient, the quantity of the fluid administered to the patient, and the estimated extracorporeal blood content of the physical sample.19. The method of claim 18 , wherein tracking the quantity of the fluid administered to the patient intravenously comprises tracking the quantity of a known composition administered to the patient according to a transfusion rate claim 18 , wherein estimating hematocrit of the patient comprises estimating the hematocrit of the patient further based on the known composition of the fluid.20. The method of claim 18 , wherein extracting the feature from the area of the image correlated with the physical sample comprises extracting a subset of pixels from a set of pixels within the area of the image.21. ...

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Номер записи: 97
08-01-2015 дата публикации

Methods and systems for a high-resolution brain image pipeline and database program

Номер: US20150010223A1
Автор: Guillermo Sapiro, Noam Harel
Принадлежит: Surgical Information Sciences Inc

A volumetric segmentation method is disclosed for brain region analysis, in particular but not limited to, regions of the basal ganglia such as the subthalamic nucleus (STN). This serves for visualization and localization within the sub-cortical region of the basal ganglia, as an example of prediction of a region of interest for deep brain stimulation procedures. A statistical shape model is applied for variation modes of the STN, or the corresponding regions of interest, and its predictors on high-quality training sets obtained from high-field, e.g., 7 T, MR imaging. The partial least squares regression (PLSR) method is applied to induce the spatial relationship between the region to be predicted, e.g., STN, and its predictors. The prediction accuracy for validating the invention is evaluated by measuring the shape similarity and the errors in position, size, and orientation between manually segmented STN and its predicted one.

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Номер записи: 98
10-01-2019 дата публикации

METHOD AND SYSTEM FOR QUANTIFYING LIMITATIONS IN CORONARY ARTERY BLOOD FLOW DURING PHYSICAL ACTIVITY IN PATIENTS WITH CORONARY ARTERY DISEASE

Номер: US20190008462A1
Автор: Taylor Charles A.
Принадлежит:

Embodiments include a system for determining cardiovascular information for a patient with coronary artery disease. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart and create a model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create, for a given level of physical activity, a physics-based model of blood flow through the patient's heart simulated during a selected level of physical activity; determine and normalize one or more values of at least one blood flow characteristic within the patient's heart during the simulated level of physical activity; and compare the one or more normalized values of the at least one blood flow characteristic to a threshold to determine whether the level of physical activity exceeds an acceptable level of risk. 130-. (canceled)31. A system for quantifying limitations in coronary artery blood flow during exercise in a patient with coronary artery disease , the system comprising:at least one computer system configured for:receiving data regarding geometry of a patient's vasculature;creating a geometric model representing the geometry of at least a portion of the patient's vasculature, the geometric model reflecting vascular geometry at a first physiological state;computing, using the geometric model, a blood flow characteristic of blood flow through the geometric model for a second physiological state, different from the first physiological state; anddetermining a score quantifying a risk of a of injury to the patient at the second physiological state, based on the computed blood flow characteristic.32. The system of claim 31 , wherein the at least one computer system is further configured for:generating a physics-based model based on the geometric model; andcomputing the blood flow based on the physics-based model.33. The system of claim ...

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Номер записи: 99
10-01-2019 дата публикации

Optical Feedback RF Ablator and Ablator Tip

Номер: US20190008586A1
Автор: John W. Sliwa, Stephen A. Morse, Zhenyi Ma
Принадлежит: St Jude Medical LLC

An ablation catheter comprises an elongated catheter body; at least one ablation element disposed in a distal portion which is adjacent the distal end of the catheter body; an illumination optical element disposed in the distal portion, the illumination optical element being light-transmissive to emit light from the illumination optical element to the targeted tissue region; and a collection optical element disposed in the distal portion, the collection optical element being light-transmissive to collect one or more of returned, backscattered or newly excited light from the targeted tissue region. The illumination or excitation optical element and the collection optical element are axially spaced from one another and axially optically isolated from one another within the distal portion to substantially prevent light from traveling between the illumination optical element and the collection optical element along a path within the distal portion.

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Номер записи: 100