СИСТЕМА И СПОСОБЫ ПОДДЕРЖАНИЯ УЗКОГО ПРОСВЕТА В ОРГАНИЗМЕ

Группа изобретений включает устройство для поддержания узкого просвета в организме, устройство для диагностики узкого просвета в органе с трубчатой анатомической структурой в организме, устройство для диагностики фаллопиевых труб, способ поддержания узкого просвета в организме (варианты), способ поддержания фаллопиевых труб узкого просвета, относятся к области медицины и предназначены для диагностической визуализации или обработки терапевтическими средствами для эффективной поддержки узкого просвета в организме. Устройство для поддержания узкого просвета в организме содержит механизм гидравлического проталкивания и извлекающий механизм. Механизм гидравлического проталкивания для проталкивания части для получения изображения или терапевтической части через указанный узкий просвет в организме имеет конфигурацию для проталкивания указанной части для получения изображения или указанной терапевтической части относительно указанного механизма гидравлического проталкивания и через узкий просвет ...

СИСТЕМА И СПОСОБ ОПРЕДЕЛЕНИЯ МЕСТА РАСПОЛОЖЕНИЯ И ИДЕНТИФИКАЦИИ ФУНКЦИОНАЛЬНЫХ НЕРВОВ, ИННЕРВИРУЮЩИХ СТЕНКУ АРТЕРИЙ, И КАТЕТЕРЫ ДЛЯ НИХ

Группа изобретений относится к области медицины и медицинской техники. Система содержит: катетер, выполненный с возможностью подачи электрического тока на внутреннюю стенку почечной артерии для стимуляции нерва, иннервирующего почечную артерию; измерительное устройство для измерения физиологических параметров, связанных с иннервацией почечной артерии; вычислительное устройство, связанное с измерительными устройствами для вычисления значений физиологических параметров; отображающее устройство для идентификации парасимпатического или симпатического нерва, иннервирующего внутреннюю стенку почечной артерии. Для картирования нерва, иннервирующего стенку почечной артерии, катетер вводят в полость артерии таким образом, что кончик катетера контактирует с участком, расположенным на внутренней стенке почечной артерии. Измеряют значения физиологических параметров перед приложением электрического тока. Осуществляют стимуляцию. При этом управляют электрическим током таким образом, что он имеет значение ...

СИСТЕМА И СПОСОБ ОПРЕДЕЛЕНИЯ МЕСТА РАСПОЛОЖЕНИЯ И ИДЕНТИФИКАЦИИ ФУНКЦИОНАЛЬНЫХ НЕРВОВ, ИННЕРВИРУЮЩИХ СТЕНКУ АРТЕРИЙ, И КАТЕТЕРЫ ДЛЯ НИХ

... 1. Система для картирования парасимпатического или симпатического нерва, иннервирующего стенку почечной артерии, причем указанная система содержит:(i) катетер, выполненный с возможностью подачи электрического тока в одно или более мест на внутренней стенке почечной артерии, достаточного для стимуляции нерва, иннервирующего указанную почечную артерию,(ii) одно или более измерительных устройств для измерения одного или более физиологических параметров, связанных с указанной иннервацией почечной артерии, причем указанные физиологические параметры выбраны из группы, содержащей: систологическое давление крови, диастолическое давление крови, среднее артериальное давление и частота сердечных сокращений,(iii) вычислительное устройство, выполненное с возможностью связи с указанным одним или более измерительных устройств для вычисления любого увеличения или уменьшения в значениях указанных физиологических параметров по отношению к исходному уровню,(iv) отображающее устройство для отображения указанного ...

СПОСОБ КОНСТРУИРОВАНИЯ ОРОШАЕМОГО БАЛЛОННОГО КАТЕТЕРА

СИСТЕМА И СПОСОБЫ ПОДДЕРЖАНИЯ УЗКОГО ПРОСВЕТА В ОРГАНИЗМЕ

... 1. Устройство для поддержания узкого просвета в организме, содержащее:механизм гидравлического проталкивания для проталкивания части для получения изображения или терапевтической части через указанный узкий просвет в организме; иизвлекающий механизм для извлечения указанной части для получения изображения или указанной терапевтической части из указанного узкого просвета в организме.2. Устройство по п. 1, дополнительно содержащее рукоятку, которая содержит один или несколько переходников люэра, один из которых выполнен с возможностью создания гидравлического давления для гидравлического проталкивания указанной части для получения изображения или указанной терапевтической части через указанный узкий просвет в организме.3. Устройство по п. 2, дополнительно содержащее переходник люэра для проводника, который находится в указанной рукоятке и выполнен с возможностью введения проводника для подачи электропитания и передачи сигналов для облегчения функции получения изображения, осуществляемой указанной ...

УСТРОЙСТВО И СПОСОБ ДЛЯ НЕОТЛОЖНОГО ЛЕЧЕНИЯ ОСТАНОВКИ СЕРДЦА

VORRICHTUNG FÜR TRANSLUMINALE EINGRIFFE MIT GEFÜHRTEN KATHETERN ODER ANDEREN GERÄTEN, DIE DIE GEFÄSSWANDE DURCHDRINGEN

Arrangement for interference-free time and position dependent impedance spectroscopy in hollow organs; has non-invasive measurement electrodes to fit shape of organ arranged on catheter

The arrangement has non-invasive measurement electrodes with small electrode polarisations, which fit the shape of the organ and are arranged on a hollow catheter with a larger outer diameter than the inner diameter of the organ or an elastic balloon catheter. The catheter is connected to a conventional retraction unit, which has a sensor for the retraction distance and any axial rotation. The catheter is connected to a circuit to generated pulses of a selected frequency between 0.1 kHz and 1 MHz and a measuring arrangement to determine the impedance spectrum from the pulse formations. The sensor at the retraction unit and the measurement arrangement connected to the catheter are connected to a processor circuit to determine the pulse formation as a function of the position of the catheter and its axial rotation.

CATHETER CONTROL DEVICE

A control device 41 preferably for a urinary catheter 2 includes an inlet port 11, an outlet port 12 connected with a urine collection receptacle 13, a flow conduit 14 and a normally closed valve 15, responsive to a timer 17 and optionally a pressure sensor 21 to open and close the valve. The pressure sensor may override the timer to open the valve 15. The bladder drainage and refill periods as set by the timer may be reprogrammable via interface 33. The device may also include a pH sensor 44, a flow meter 45, a manual overrride switch 35 to open the valve and a data transmission output interface.

Flow sensor arrangement and method for using a flow sensor arrangement

A flow sensor arrangement (S35, S36. S37, S39,...) is located on an elongated body (C1, C2, C3,...) for measuring the flow of a fluid, with one or more flow sensors (S1, S2, S3,...) being arranged on the elongated body (C1, C2, C3,...) to measure the flow along different spatial directions.

Bladder mapping

CATHETER FOR PRESSURE MEASUREMENT WITH SEVERAL LINES

ELECTRICAL PHYSIOLOGY CATHETER WITH GUIDANCE WIRE

BLUTFLUSS OKKLUDIERENDE, TEMPERATURE-MEASURING CATHETERS

TONOMETRI CATHETER DEVICE AND PROCEDURE WITH REMOTE SENSOR

TONOMETRI CATHETER COMBINATION

INTRAAORTALER CATHETER TO THE PERFUSION AND KONSERVATION THE KIDNEY

DEVICE FOR THE TELEMETERING OF MEANS OF A PRINTING MEASURING CATHETER

OESOPHAGEAL PROBE

BALLOON CATHETER WITH ULTRASONIC TRANSDUCERS

Embodiments of the present invention include a medical apparatus that includes a probe having a distal end configured for insertion into a body cavity and containing a lumen that opens through the distal end, and an inflatable balloon deployable through the lumen into the body cavity, the balloon having an exterior wall. The medical apparatus also includes a flexible printed circuit board having a first side attached to the exterior wall of the inflatable balloon and a second side opposite the first side, and an ultrasonic transducer mounted on the first side of the flexible printed circuit board and encapsulated between the exterior wall of the balloon and the flexible printed circuit board. (0 (o I~tC) LO V') 0 L) aOf ...

Systems, devices and methods for sensing physiologic data and draining and analyzing bodily fluids

Abstract Systems, devices and methods for sensing physiologic data and draining and analyzing bodily fluids are described which are capable of sensing physiologic data based on sensors 5 incorporated into a catheter adapted to reside in any of a urinary tract, gastrointestinal tract, rectal location, pre-peritoneal, pleural space or other body cavity. The devices aid emptying of the bladder, measure urine output and various urine parameters such as oxygen tension, urine conductance and urine specific gravity, monitor renal function, analyze urine parameters, including urine content, including the presence of infection, and track and/or control fluid 10 administration. 16639503_1 (GHMatters) P43852AU01 ...

Systems and methods for maintaining a narrow body lumen

SYSTEMS AND METHODS FOR MAINTAINING A NARROW BODY A device (100) for providing at least one of diagnosis and treatment of a fallopian tube of a patient, said device (100) comprising: an elongate catheter (304) comprising a distal end portion (426) configured to be inserted into the patient during use and a proximal end portion that extends out of the patient during use; an imaging device or illumination device (408) configured to image or illuminate the fallopian tube at a location distal of said distal end portion (426); and said distal end portion (426) includes an enlarged distal portion (430) configured to contact the walls of the fallopian tube and create a space around said imaging or illumination device (408).

METHOD AND APPARATUS FOR VERIFYING DATA MEASURED BY SEVERAL MEANS IN REAL-TIME

Luminal impedance device with integrated circuit modules

Impedance devices with integrated circuit modules and method of using the same to obtain luminal organ information. In one embodiment, a device comprises an elongated body for at least partial insertion into a mammalian luminal organ and having a first conductor extending therethrough, a proximal electrical unit connected to the elongated body to deliver power along the first conductor, and a sensor substrate located at or near a distal end of the elongated body and comprising a circuit module operable and/or configured to direct the sizing portion to obtain sizing data and the pressure sensor to obtain pressure data, and facilitate transmission of the sizing data and/or the pressure data to the proximal electrical unit.

Cardiac function evaluation system

A device adapted for determining cardiac viability, wherein said device includes: a cannula having a hollow body and at least a distal end adapted for insertion into a heart and operator end for adapted for an operator to position the catheter in the ventricular apex and adapted for connection to a plumbing system; an inflatable balloon positioned near to the distal end in fluid communication with the hollow body to allow for selected inflation of the balloon, a controller adapted to calculate the viability of the heart from pressure data detected within cannula or balloon which is inflated to various degrees with an incompressible fluid.

Ultrasound sequencing system and method

A system comprises a catheter configured for delivery to a body cavity defined by surrounding tissue; a plurality of ultrasound transducers coupled to a distal end of the catheter; and an electronics module configured to selectively turn on/off each ultrasound transducer according to a predetermined activation sequence and to process signals received from each ultrasound transducer to produce at least a 2D display of the surrounding tissue. A user can selectively calculate and display various aspects of cardiac activity. The user can display Dipole Density (DDM), Charge Density (CDM), or Voltage (V-V). The shape and location of the chamber (surface), and the potentials recorded at electrodes can be displayed. The system can also change back and forth between the different display modes, and with post processing tools, can change how various types of information is displayed. Methods are also provided.

Ablation and temperature measurement devices

A temperature measurement probe for a patient is provided. The probe includes a sensor assembly and produces a temperature map comprising temperature information for multiple patient locations.

Systems, devices and methods for sensing physiologic data and draining and analyzing bodily fluids

Systems, devices and methods for sensing physiologic data and draining and analyzing bodily fluids are described which are capable of sensing physiologic data based on sensors incorporated into a catheter adapted to reside in any of a urinary tract, gastrointestinal tract, rectal location, pre-peritoneal, pleural space or other body cavity. The devices aid emptying of the bladder, measure urine output and various urine parameters such as oxygen tension, urine conductance and urine specific gravity, monitor renal function, analyze urine parameters, including urine content, including the presence of infection, and track and/or control fluid administration.

Pressure-sensing catheters and related methods

A multi-lumen catheter can be used to measure pressure at multiple locations within the vasculature. The multi-lumen catheter can include multiple segments, such as a proximal portion, an intermediate portion, and a distal portion. A segment of a multi-lumen catheter may differ from another segment of the same multi-lumen catheter in radiodensity, hardness, and/or some other characteristic. Some multi-lumen catheters are designed to permit measurements of pressure in different lumens.

MULTI-FUNCTION CONDUCTING ELEMENTS FOR A CATHETER

Described embodiments include an apparatus that includes an expandable structure, configured for insertion into a body of a 5 subject, and a plurality of conducting elements coupled to the expandable structure. Each of the conducting elements comprises a respective coil and has an insulated portion that is electrically insulated from tissue of the subject, and an uninsulated portion configured to exchange signals with the 0 tissue, while in contact with the tissue. Other embodiments are also described. 3203295v1 C*4 Q0 co CY) cn C) z co w co LU C%4 Cl") ...

Mapping catheter

An analyzing apparatus and method

VEIN OCCLUSION DEVICES AND METHODS FOR CATHETER-BASED ABLATION

Medical devices and methods for deriving an indication of occlusion of a blood vessel from one or more physiologic sensor are disclosed. The physiological parameters contemplated for implementation in accordance with embodiments of the disclosure may include pressure, flow, force, temperature, or tension. An exemplary device comprises a catheter having an expandable chamber coupled to a distal end portion of the catheter shaft. In various embodiments, one or more physiologic sensors may be disposed on the catheter shaft and electrically coupled to control electronics that may be provided in a console for measurement of a physiologic signal. Alternatively, an external sensor may be disposed in fluid communication with a lumen of the catheter to derive a physiological parameter such as pressure via mechanical coupling of pressure distal to the expandable chamber to the fluid in the lumen. The parameters measured by the physiologic sensor(s) provide a measure of the physiological parameters ...

ENDOTRACHEAL TUBE APPARATUS

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface and a first location configured to be positioned at the patient's vocal folds. A first electrode is formed on the exterior surface of the endotracheal tube substantially below the first location. A second electrode is formed on the exterior surface of the endotracheal tube substantially above the first location. The first and second electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient.

AUTORETROPERFUSION DEVICES, SYSTEMS, AND METHODS FOR ACHIEVING VENOUS ARTERIALIZATION

Devices, systems, and methods for providing retroperfusion to at least one ischemic tissue in a minimally invasive manner are disclosed. At least some of the embodiments disclosed herein enable an anastomosis to be formed between a vein and an artery without the use of sutures and through a non-invasive procedure. In addition, various disclosed embodiments provide a cannula device comprising a Y-configuration for bifurcating arterial flow between an anastomosis and the underlying artery. The devices, systems and methods herein can further provide simultaneous autoretroperfusion therapy to more than one area of an ischemic tissue.

AUTORETROPERFUSION DEVICES, SYSTEMS, AND METHODS FOR ACHIEVING VENOUS ARTERIALIZATION

Devices, systems, and methods for providing retroperfusion to at least one ischemic tissue in a minimally invasive manner are disclosed. At least some of the embodiments disclosed herein enable an anastomosis to be formed between a vein and an artery without the use of sutures and through a non-invasive procedure. In addition, various disclosed embodiments provide a cannula device comprising a Y-configuration for bifurcating arterial flow between an anastomosis and the underlying artery. The devices, systems and methods herein can further provide simultaneous autoretroperfusion therapy to more than one area of an ischemic tissue.

ENDOTRACHEAL TUBE APPARATUS

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive ink electrodes are formed on the exterior surface of the endotracheal tube. The conductive ink electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least one conductor is coupled to the conductive ink electrodes and is configured to carry the EMG signals received by the conductive ink electrodes to a processing apparatus.

ORAL-ESOPHAGEAL-GASTRIC DEVICE WITH ESOPHAGEAL CUFF TO REDUCE GASTRIC REFLUX AND/OR EMESIS

A nasogastric/orogastric (Ng/Og) airway protection device includes an elongate device body having a distal end for insertion into the stomach through the esophagus and a proximal end. A main lumen extends the length of the device and is configured for at least one of gastric decompression, enteral feeding and enteral medication administration. A sump port is at the distal end. A sump lumen is formed the length of the device body and configured for venting gas and preventing adherence of the device against the gastric wall. An inflatable esophageal cuff is carried by the device body mid-esophagus and an inflation lumen is formed within the device body and connects the inflatable esophageal cuff through which the esophageal cuff is inflated and deflated. Upon inflation of the esophageal cuff, emesis and/or reflux is blocked from passing out of the stomach past the esophageal cuff positioned mid-esophagus to protect a patient's airway.

DEVICE, SYSTEM, AND METHOD FOR DETECTING, LOCALIZING, AND CHARACTERIZING PLAQUE-INDUCED STENOSIS OF A BLOOD VESSEL

The present invention is of system, device, and method for detection, localization, and characterization of plaque-induced stenosis of a blood vessel. More particularly, the present invention relates to a balloon catheter (101) having an expandable balloon (100) insertable into a blood vessel, which balloon comprises a plurality of pressure sensors (110, 120, 130, 140) operable to detect stenosis of the vessel, and further operable to report degrees of compressibility of stenotic regions of plaque within the vessel, thereby distinguishing between standard and vulnerable plaque.

TEMPERATURE SENSING CATHETER

A thermal sensing catheter (114) for detecting and isolating unstable arterial plaque. Miniaturized temperature sensors (106), preferably in the form of microthermistors, are embedded into expandable presentation elements (110) disposed at the distal end of a catheter. The sensors (106) may then be deployed to measure the surface temperature of the inner wall of coronary arteries or other vessels at multiple sites to identify sites of elevated temperature indicative of unstable plaque. A plurality of thermal sensors (106) are embedded into the sides of polymeric or metallic sensing elements (108) which expand out from the centerline of a catheter (114) toward the inner vessel walls.

DEVICES AND METHODS FOR PERCUTANEOUS INTRATUMORAL THERAPY DELIVERY

Percutaneous therapy or drug delivery devices are described herein. The device can include one or multiple lumens inside a cannula or catheter body. The device can include features for reducing or preventing backflow or reflux of infusate along the device insertion track, such as one or more bullet noses, over tubes, and/or micro-tips. The device can be used in any of a variety of treatment methods, including to inject cancer therapy medicinal products directly into pulmonary tumors or tumors located in other regions of the body. The device can include features to keep the distal tip secure during patient respiration or during other patient movement, and can reduce the incidence of reflux during therapy delivery.

PRESSURE CATHETER DEVICE

A pressure-sensing catheter (10) comprises an elongate member (15) and a monitor lumen (30). The pressure-sensing catheter may have a hollow pressure-compliant member (40) in fluid communication with the monitor lumen and thereby define a fluid column. A connector apparatus can be in fluid communication with the monitor lumen, and can comprise a first complementary connector (72) and a second complementary connector (98). One of the first complementary connector and the second complementary connector can have a pressurizing device that can displace a volume of fluid located within a bore of the other complementary connector into the fluid column, wherein the ratio of the volume of displaced fluid to the volume of the fluid column ranges from about 1:2 to about 1:4. The pressure catheter can comprise a radio-opaque band circumscribing the exterior of the elongate member.

SCALING IMPEDANCE LOCATION MEASUREMENTS OF A BALLOON CATHETER

A method includes, in a processor, receiving position signals that are indicative of positions of (i) multiple electrodes disposed on an inflatable balloon fitted at a distal end of a catheter, and (ii) first and second electrodes fitted on a shaft of the catheter, on either side of the balloon. The positions of the multiple electrodes disposed on the balloon are calculated based on the received position signals and based on a known distance between the first and second electrodes.

METHOD AND APPARATUS FOR CRYOGENIC TREATMENT OF A BODY CAVITY OR_LUMEN

APPARATUS FOR ASSESSMENT OF MICROVASCULAR DYSFUNCTION

Methods and devices for assessment of microvascular dysfunction, such as microvascular obstruction (MVO) and other dysfunctional diseases of the microvasculature of many organs, including the heart. The present subject matter provides novel devices and methods to successfully diagnose, restore patency, open and preserve flow, and limit reperfusion injury in organs and cases with microvascular dysfunction. The present subject matter provides apparatus and method to detect, measure and treat microvascular dysfunction in real time during scenarios such as invasive angiographic/therapeutic procedures. Such procedures include therapy for organ systems including the heart (acute myocardial infarction - primary percutaneous coronary intervention (PPCI)), brain stroke (CVA), bowel ischemia/infarction, pulmonary emboli/infarction, critical limb ischemia/infarction, renal ischemia/infarction, and others. The present subject matter provides various systems including an infusion and sensing catheter ...

SYSTEM AND METHODS FOR IMPROVED ACCESS TO VERTEBRAL BODIES FOR KYPHOPLASTY, VERTEBROPLASTY, VERTEBRAL BODY BIOPSY OR SCREW PLACEMENT

... ²²²A method of determining the size and/or placement of screws or other ²instruments in pedicles during surgery in a selected spinal area, comprising ²generating a dimensionally true three-dimensional image of the bony spine in ²the selected spinal area; hollowing out the vertebra in the three-dimensional ²image with cortical wall thicknesses selected by a surgeon performing the ²surgery; determining the narrowest cross section (isthmus) within each ²pedicle; generating a straight line starting at the center of the isthmus and ²extending inwardly to a point centered within the anterior cortex so that it ²is positioned concentrically within the pedicle without touching the walls ²thereof, the line terminating inside the vertebral body a predetermined ²distance from the anterior inner cortical wall and extending outwardly in the ²opposite direction to penetrate the posterior pedicle cortex; expanding the ²line concentrically and radially to a cross sectional size that is less than ²that of ...

DEVICE AND METHOD FOR VIRTUAL ANGIOGRAPHY

A system and method for performing a medical procedure is provided. The system includes a device having a shaft that generally extends from a proximal end to a distal end along a longitudinal axis. The distal end of the device is configured to identify a topographical profile of a lumen, wherein the topographical profile is determined by traversing the device a distance along the longitudinal axis of the lumen. The device also includes at least one of a plurality of projections movably coupled to the distal end and configured to provide a coupling with the lumen by extending in a direction substantially orthogonal to the longitudinal axis, and at least one radiopaque marker coupled to the distal end and designed to provide a contrast during imaging of the device.

PHYSIOLOGICAL SENSOR DELIVERY DEVICE AND METHOD

An intravaseular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.

COMPLIANT ELECTRODE FOR EMG ENDOTRACHEAL TUBE

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having a first cuff and a second cuff. Conductive ink electrodes are formed on an exterior surface of the first cuff. The conductive ink electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least one conductor is coupled to the conductive ink electrodes and is configured to carry the EMG signals received by the conductive ink electrodes to a processing apparatus.

TEMPERATURE SENSING CATHETER

An improved catheter is described. The catheter may have an inflation lumen reinforced with a metal support, such as a coil, to prevent collapse and deflation of the inflation lumen, while leaving a minimal impact on the size of the catheter. The catheter may be manufactured with a temperature sensing strip permanently integrated into the catheter during the manufacturing process. The temperature sensing strip is able to wirelessly send information regarding a patient's temperature to an external display, where it may be available for viewing by a care provider. Additionally, the drainage lumen of the catheter is preferably coated with a hydrophobic coating or treatment, and/or formed to include a patterned microstructure surface design, such as superhydrophobic patterned surface.

DEVICES, SYSTEMS AND METHODS FOR LOCALLY MEASURING BIOLOGICAL CONDUIT AND/OR LESION COMPLIANCE, OPPOSITION FORCE AND INNER DIAMETER OF A BIOLOGICAL CONDUIT

The present invention is directed in various methods, devices and systems relating to systems and methods for measuring and calculating a biological conduit's, e.g., a blood vessel, inner diameter, the opposition force of the conduit's wall on an expanding balloon disposed therein and the conduit and/or lesion compliance to the expanding balloon.

ENDOTRACHEAL TUBES AND SYSTEMS AND METHODS FOR EVALUATING BREATHING

The present application relates to endotracheal tubes and to systems and methods for detecting airway edema and evaluating breathing with an endotracheal tube. An example endotracheal tube includes a distal portion, a proximal portion, and a linker portion. The linker potion couples the distal portion and the proximal portion. The linker portion includes at least two struts. The struts extend between the distal portion and the proximal portion. Also, there is at least one opening defined between and along the length of the struts. The linker portion is configured to contact the vocal cords of the subject when in use.

ELECTRONIC CATHETER STETHOSCOPE

An electronic catheter stethoscope measures and analyzes acoustic fields and dynamic pressure variations in the gaseous or liquid fluid inside a conventional medical catheter that is positioned in a patient's urologic, digestive, reproductive, cardiovascular, neurological or pulmonary system. Measurement transducers are installed in a housing connectable to multiple preselected medical catheters. The transducers detect bodily functions that are transmitted to the preselected catheter from within the body. The transducers, housing, electrical interface and signal processing electronics are positioned outside the body.

ENDOCARDIAL MAPPING SYSTEM

A system for mapping electrical activity of a patient's heart includes a set of electrodes (19) spaced from the heart wall (18) and a set of electrodes (24, 26) in contact with the heart wall (18). Voltage measurements from the electrodes are used to generate three-dimensional and two-dimensional maps of the electrical activity of the heart.

APPARATUS FOR MONITORING BRONCHIAL ELECTROCARDIOGRAM

METHODS AND APPARATUS FOR MYOCARDIAL REVASCULARIZATION

An elongate probe for providing irradiation treatment of the heart, said probe having a distal end for engaging heart tissue of a subject, including a waveguide, which conveys radiation to the heart tissue; and a sensor, adjacent the distal end of the probe, which generates signals for use in controlling the treatment.

METHOD FOR VELOCITY COMPONENT VECTOR MAPPING

An elongate probe apparatus (20) for insertion into the body of a subject, comprising: a structure (24) having a substantially rigid configuration; a plurality of physiological sensors (26, 28, 30), which generate signals responsive to a physiological activity, said sensors (26, 28, 30)having substantially fixed positions on said structure (24) in said configuration; and one or more devices that generate position signals indicative of the positions of the physiological sensors on said structure in said configuration.

METHOD AND APPARATUS FOR CONTROLLING BODY TEMPERATURE

The present invention provides a method and apparatus for controlling the internal body temperature of a patient. According to the present invention, a catheter (20) is inserted into a large blood vessel of a patient. By selectively heating or cooling a portion (15) of the catheter lying within the blood vessel, the patient's body temperature may be increased or decreased as desired. The invention will find use in treating undesirable conditions of hypothermia or hyperthermia, or for inducing a condition of artificial hypothermia when desired. The method and system further provide for the cooling of initially hyperthermic patients whose blood or body temperature has been cooled below the desired target temperature.

OVER-THE-WIRE EP CATHETER

An over-the-wire (32) electrophysiology catheter (10) which has an emitting electrode (17) on the distal tip (12) electrically connected to a source of high frequency electrical energy. The intravascular device (1 0) is configured to be advanced through a patient's cardiac veins or coronary arteries and preferably is also provided with sensing electrodes (18) for detecting electrical activity of the patient's heart from within a blood vessel of the heart. The device forms large lesions in tissue adjacent to the blood vessel in which the device is located without significantly damaging the blood vessel to effectively terminates signals causing arrhythmia.

INFUSION CATHETER FOR CURATIVE EFFECT AT LEAST ON ONE PARTIAL OR COMPLETE OBSTRUCTION IN THE CHANNEL BODY

DEVICE, METHOD AND PROGRAM MONITORING TISSUE PERFUSION

L'invention concerne un dispositif (1) de monitorage de perfusion d'un tissu d'un organe (3), comprenant - un capteur de perfusion (2) configuré pour détecter une perfusion du tissu, et - au moins un capteur d'activité (4) configuré pour détecter une activité musculaire de l'organe (3), ledit au moins un capteur d'activité (4) étant disposé à proximité du capteur de perfusion (2), lesdits capteurs étant configurés pour être associés à une unité de traitement (5). L'invention concerne en outre un procédé et programme de monitorage associés.

MICROPROBE FOR NUCLEAR MAGNETIC RESONANCE ANALYSIS

INFUSION CATHETER DEVICE FOR PROCESSING AT LEAST ONE PARTIAL OR COMPLETE OBSTRUCTION IN A CONDUIT, SUCH AS CONDUIT BODY

L'invention concerne un dispositif formant cathéter d'infusion. Ce dispositif cathéter 10 comprend une forme sensiblement tubulaire allongée définissant un axe longitudinal, une extrémité distale (D) et une extrémité proximale (P), configuré pour être introduit dans un conduit (50) ayant une paroi interne (54) et une paroi externe (56), comprenant au moins une obstruction (60) ou occlusion partielle ou totale à traiter, ledit dispositif comprenant à son extrémité distale (D) un ou plusieurs orifices (16, 18, 20, 22) d'infusion d'un liquide d'infusion (LI), et en amont du ou des orifices d'infusion, côté proximal (P) du cathéter d'infusion (10), au moins un élément obturateur (70) d'obturation provisoire configuré pour traiter ladite obstruction (60) ou occlusion et réaliser l'infusion du liquide d'infusion (LI) en aval de l'élément obturateur (70) et en position d'obturation. Ce dispositif est notamment adapté à la chirurgie cardiaque et à la cardiologie interventionnelle.

COMPARTMENT SYNDROME MONITORING SYSTEMS AND METHODS

dispositivo distribuidor de sensor fisiológico e método

SMART EXPANDABLE MEMBER FOR MEDICAL APPLICATIONS

Devices and methods for assessing the compliance of vessel lumens and hollow portions of organs are described. The devices and methods are particularly adapted for determining the compliance of the native heart valves to facilitate the later implantation of a prosthetic heart valve. The devices are typically catheter-based having an expandable member fixed to a distal end of the catheter. Located within the expandable member is an imaging member. The methods typically comprise deploying the balloon percutaneously to a target location, expanding the balloon, and determining the compliance of a lumen, particularly a cardiac valve. An optical coherence tomography apparatus is a preferred apparatus for determining compliance.

SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN

A catheter is provided for placement within a body lumen, the catheter including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end. The catheter further includes at least one delivery waveguide and at least one collection waveguide positioned along the flexible conduit, the at least one delivery waveguide and the at least one collection waveguide constructed and arranged to transmit radiation at a wavelength in a range of about 250 to 2500 nanometers. The catheter further includes a flexible, expandable first surface encircling surrounding a segment of the conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located within the flexible, expandable first surface, and the distal end of at least one of the at least one delivery waveguide and the at least one collection waveguide tethered to the flexible, expandable first surface radially ...

SHAPE SENSING DEVICES FOR REAL-TIME MECHANICAL FUNCTION ASSESSMENT OF AN INTERNAL ORGAN

A system and method for functioning organ assessment include a sensing enabled flexible device (102) having an optical fiber configured to sense induced strain continuously over a length of the flexible device. The flexible device includes a manipulation mechanism (105) configured to permit engagement with an interior wall of an organ over the length. An interpretation module(115) is configured to receive optical signals from the optical fiber between two phases of movement of the organ while the organ is functioning and to interpret the optical signals to quantify parameters associated with the functioning of the organ.

DEVICE AND METHOD FOR MEASURING FETAL BLOOD PH

A hand-mounted device for obtaining a sample of blood from the scalp of a fetus and for measuring the pH of the blood sample includes a lancet for incising the scalp of the fetus, a capillary for obtaining a drop-sized sample of blood and a pH electrode within the capillary for analyzing the pH of the blood. Optionally, a motorized actuator may be provided for automatically advancing and withdrawing the lancet and the capillary. The pH measuring device includes an isolating mechanism, in the form of an everting bell-shaped member, an inflatable balloon member or an expandable funnel member, and a flushing/aspiration lumen, for clearing the distal region of the device of amniotic fluid while in use.

DEVICE, SYSTEM, AND METHOD FOR DETECTING AND LOCALIZING OBSTRUCTION WITHIN A BLOOD VESSEL

The present invention is of system, device, and method for detecting and localizing obstruction in a blood vessel (110). More particularly, the present invention is of a balloon catheter (201) having an expandable balloon (200) which comprises a plurality of strain gauges (202a,b,c;212a,b,c;222a,b,c) operable to report relative degrees of expansion of local portions of a wall of the expandable balloon (200). Incomplete expansion of a local portion of the balloon (200), under common pressure within the balloon (200), indicates presence of an obstruction, such as a region of plaque, within the blood vessel (110).

SYSTEMS AND PROCESSES FOR OPTICAL IMAGING OF LUMINAL ANATOMIC STRUCTURES

Exemplary embodiments of an apparatus for obtaining data for at least one portion within at least one luminal or hollow sample can be provided. For example, the exemplary apparatus can include a first optical arrangement configured to transceive at least one electromagnetic radiation to and from the portion. A second arrangement may be provided that can at least partially enclose the first arrangement. At least one third arrangement may be provided which is configured to be actuated so as to expand, at least in part, beyond a periphery of the second arrangement. Such exemplary third arrangement can be structured to facilitate a fluid flow and/or a gas flow therethrough. Further, a fourth arrangement may be provided which can be structured to (i) actuate a particular number of the third arrangement and/or (ii) adjust a distance between at least two outer portions of the third arrangement. According to one exemplary embodiment, the third arrangement can be a plurality of the third arrangements ...

EXPANDABLE DEVICE TO PROFILE THE WALL OF A HOLLOW BODY ORGAN

An expandable device (40) for profiling the wall of a hollow body organ includes a flexible, expandable member (42) capable of conforming to the wall of a cavity or hollow body organ. A temperature sensor (48) within the interior of the expandable member can move about and measure the temperature at different locations. One expandable member can be an elastomeric balloon for conforming to the walls of the hollow body organ and which can be coated or doped with a material (46) that responds to a change of temperature of the cavity wall. This change can be assessed by the sensor, e.g., a fiberoptic that can transmit light and collect the reflected light. The fiberoptic can have a reflection mechanism (50) at its tip to direct the angle of incidence. The controller can measure and process the collected signal to produce a graph representing, the temperature profile.

DEVICE, SYSTEM, AND METHOD FOR DETECTING AND LOCALIZING OBSTRUCTION WITHIN A BLOOD VESSEL

The present invention is of system, device, and method for detecting and localizing obstruction in a blood vessel. More particularly, the present invention is of a balloon catheter having an expandable balloon which comprises a plurality of strain gauges operable to report relative degrees of expansion of local portions of a wall of the expandable balloon. Incomplete expansion of a local portion of the balloon, under common pressure within the balloon, indicates presence of an obstruction, such as a region of plaque, within the blood vessel.

Enteral Feeding Catheter, Computer System and Computer Program for Operating the Feeding Catheter

The invention relates to an enteral feeding catheter ( 1 ) for channelling flowable nutrient into a patient's digestive tract, such as into patients stomach, duodenum or jejunum, said catheter having a first lumen ( 2 ), having an opening ( 3 ) for connecting it to a supply for of nutrient and channelling said nutrient from the proximal end (P) to the distal end (D), the distal end (D) of the first lumen ( 2 ) being provided with several radial outlets ( 4 ) for the exit of said nutrient into patient's digestive tract, the catheter ( 1 ) further comprising a second lumen ( 7 ), for being connected to a source/sink of gas ( 26 ) and a gas pressure gauge ( 24 ) at its proximal end and being connected to an inflatable and deflatable distal balloon ( 6 ) provided on the catheter ( 1 ) near the distal end (D). The invention refers also to a computer system and computer program to operate said feeding catheter.

REMOTE VITAL SIGN DETECTION DEVICE AND SYSTEM FOR NON-IMPLANTABLE MEDICAL DEVICES AND RELATED METHODS

A remote vital sign detection device has a sensor, an integrated circuit, and antenna. The integrated circuit is in communication with the sensor and the antenna. The sensor detects and generates an electronic response from a desired vital sign such as body temperature, pulse rate, respiration rate, and blood pressure and sends a signal corresponding to that vital sign to the integrated circuit. The integrated circuit converts the vital sign signal into vital sign data and transmits the vital sign data off-board via the antenna. The vital sign data is then transmitted to an external reader. The external reader receives the vital sign data and processes it for display or read-out by medical staff. An option intermediate receiver may relay vital sign data from the vital sign detection device to the external reader. The vital sign detection device is placed in a non-implantable medical device.

SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN

In a system and method for analyzing and treating a body lumen, a lumen-expanding balloon catheter with integrated one or more delivery waveguides and one or more collection waveguides is used to perform optical analysis of the tissues surrounding the lumen during expansion. The catheter can comprise an angioplasty catheter with integrated delivery waveguides and collection waveguides to perform spectroscopy of a stenotic plaque during angioplasty.

Delivering ablation therapy in a heart chamber

A method of representing the geometry of at least a portion of a human heart chamber includes positioning a catheter in a heart chamber. The position of the catheter in the heart chamber is determined. The catheter is re-positioned and the position is re-determined a plurality of times to determine the geometry of at least a portion of the heart chamber. A three-dimensional, anatomical representation of at least a portion of the heart chamber is then created.

Apparatus for the invasive use of oximeter probes

A reflectance oximeter probe is suitably disposed at a distal end of an elongated, substantially flat, semi-rigid chassis configured for insertion into an anatomical canal, for example in the esophagus, rectum or vaginal cavity of a human patient. The reflectance probe may also be suitably employed in many veterinary applications. An electrical connector extends from a proximal end of the chassis and terminates at a plug configured for mechanical and electrical connection to a pulse oximeter box. The reflectance probe includes first and second LED's mounted to an emitter assembly and a detector assembly spaced apart from and mounted substantially coplanar with respect to the emitter assembly. The reflectance probe generates and transmits signals to the oximeter box, the signals indicative of the dynamic oxygen saturation level of the blood perfused mucus membrane tissue.

Apparatus and method for fixing electrodes in a blood vessel

Endocardial implantable cardiac leads are disclosed for applying electrical stimulation to and/or sensing electrical activity of the heart at one or more distal electrode positioned at a cardiac implantation site within a cardiac vessel adjacent to and at a desired orientation to the left ventricle or atrium of the heart. The distal electrode(s) is supported by a tubular electrode support having a diameter large enough to bear against the blood vessel wall and a support lumen that allows blood to flow through it. A retention stent extends proximally from a distal stent end fixed to the tubular electrode support to a proximal stent end. After advancement to the cardiac implantation site employing a lead delivery mechanism, the retention stent is expandable from a collapsed stent state in which the outer diameter of the retention stent is less than the inner diameter of the vessel to an expanded stent state. The expanded stent is lodged against the blood vessel wall and inhibits movement ...

Method for the detection of intracardiac electrical potential fields

A catheter method for detecting intracardiac electrical potential fields makes use of a catheter provided with sensor electrodes which are connected through conductor wires to a signal receiver and processor. The catheter is inserted into the right or left ventricle through a hole formed in a vein or artery in a catheterization theatre, or during open thorax surgery, while normal cardiac function is maintained. The catheter has a distal end portion which may be inflatable, the size and shape of this end portion being such that the sensor electrodes are spaced substantially from the wall of the cardiac chamber in use of the catheter.

CHARGER FOR PRESSURE SENSING CATHETER

A charger for charging a pressure sensing catheter is provided. The charger can include a plurality of charging ports for receiving a portion of the proximal section of the pressure sensing catheter. The charging port may include an engagement portion for engaging with the portion of the proximal section of the pressure sensing catheter such that when the engagement portion engages with the proximal section of the pressure sensing catheter, the engagement portion is fluidly coupled to the catheter lumen and the pressure transmission medium from the engagement portion is displaced from the engagement portion to charge the one or more balloons of the pressure sensing catheter. The charger can include a cover for covering the engagement portion. The charger can include flutes defined on a surface of each charging port to permit a predetermined volume of the pressure transmission medium to be displaced from each charging port. 130-. (canceled)31. A charger for charging one or more balloons of a pressure sensing catheter with a pressure transmission medium , the charger comprising:a charger housing; a central axis,', 'a first end,', 'a second end opposite to the first end in a first direction parallel to the central axis,', 'a connecting charging port portion located between the first end and the second end of the charging port, the connecting charging port portion forming at least a portion of a length of an interior surface of the charging port, the connecting charging port portion tapering inward toward the central axis along the length of the interior surface, the connecting charging port portion configured to contact a seal on the proximal section of the pressure sensing catheter as the proximal section of the pressure sensing catheter is received in the charging port, and', 'the pressure transmission medium therewithin;, 'a charging port configured to receive a portion of a proximal section of a pressure sensing catheter, the charging port includinga pressure ...

Surgical tissue monitoring system

A tissue monitoring system includes an introducer having an inflatable section and a plurality of electrodes disposed thereon. The electrodes are alternatively connected to an electrode contact system which includes at least one signal line and at least one measurement line for taking readings about a circumferential segment of tissue encompassed by the electrodes.

Treating Heart Tissue

Some embodiments of a system or method for treating heart tissue can include a catheter device that provides a user with the ability to perform a number of heart treatment tasks (before, during, and after a cardiac surgery or a percutaneous coronary intervention). In particular embodiments, the catheter device can be used to (i) precondition heart muscle tissue before the heart is isolated from the circulatory system, (ii) deliver cardioplegia into the coronary sinus during the cardiac surgery when the heart is isolated from the circulatory system, and (iii) control the blood flow through the heart after the heart is reconnected with the circulatory system. In some embodiments, the catheter device can perform some or all of: (i) intermittently occluding the coronary sinus, (ii) delivering a treatment fluid into the coronary sinus, and (iii) monitoring a flow rate of blood passing from the coronary sinus to the right atrium.

DEVICE, SYSTEM AND METHODS FOR MEASUREMENT OF PRESSURES IN THE URINARY TRACT

A catheter for measuring pressure in the urinary tract of a patient includes a catheter body having a proximal and distal end. A plurality of lumens is formed in the catheter body, and an adaptor is coupled to the proximal end of the catheter body. The adaptor includes a port for each lumen. A first pressure sensor, typically including a balloon, is fluidically coupled to a first lumen and is configured and positioned to measure pressure in a urethra of the patient. A second pressure sensor, also typically including a balloon, is fluidically coupled to a second lumen and is configured and positioned on the catheter body to measure pressure in a bladder of the patient. An expandable retention member, which may be coupled to a third lumen, is positioned on the catheter body between the first and second expandable pressure sensors so that the catheter body may be retained at a selected location in the urinary tract to properly position the fluid pressure sensors in the bladder and urethra, ...

ANATOMICAL VESSEL HEAT SENSORS

Heat sensors can be positioned within the esophagus of a patient so as to monitor temperature changes during ablation procedures in the heart. Some heat sensors can include a wire that defines an extended heat sensing region capable of detecting a change in the local temperature. Some heat sensors can be conformable to an inner surface of the esophageal wall to maintain contact therewith or to be in close proximity thereto.

METHOD AND APPARATUS FOR CONTROLLING A PATIENT'S BODY TEMPERATURE BY IN SITU BLOOD TEMPERATURE MODIFICATION

The present invention provides a method and apparatus for controlling the internal body temperature of a patient. According to the present invention, a catheter is inserted through an incision into a large blood vessel of a patient. By selectively heating or cooling a portion of the catheter lying within the blood vessel, heat may be transferred to or from blood flowing within the vessel and the patient's body temperature may thereby be increased or decreased as desired. The invention will find use in treating undesirable conditions of hypothermia and hyperthermia, or for inducing a condition of artificial hypothermia when desired. The method and system further provide for the cooling of initially hypothermic patients whose blood or body temperature has been warmed above the desired target level and the warming of initially hyperthermic patients whose blood or body temperature has been cooled below the desired target temperature.

IMPEDANCE DEVICES FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS

Impedance devices for obtaining conductance measurements within luminal organs. In at least one embodiment of an impedance device of the present disclosure, the device, comprises an elongated body and an detector positioned upon the elongated body, the detector comprising at least five electrodes and configured to obtain one or more conductance measurements generated using a first arrangement of four of the at least five electrodes and further configured to obtain one or more fluid velocity measurements using a second arrangement of four of the at least five electrodes when the elongated body is positioned within a fluid environment of a mammalian luminal organ, wherein the first arrangement is different from the second arrangement.

ELECTRODE CONFIGURATIONS FOR DIAGNOSIS OF ARRHYTHMIAS

An apparatus includes a shaft and an end effector at a distal end of the shaft. The end effector is sized to fit in an anatomical passageway within a subject's cardiovascular system. The end effector includes at least one electrode pair that is configured to contact cardiovascular tissue and thereby pick up electrocardiogram signals. Each electrode pair includes first and second electrodes spaced apart along a longitudinal axis from each other by a gap area located between the electrodes, the gap area having a gap length with respect to the longitudinal axis such that a length of one of the electrodes along the longitudinal axis is equal to or greater than the gap length; and a ratio of an area defined by the gap area to one electrode area is equal to or less than one.

Mapping electrophysiological data in a heart chamber

A method of acquiring and mapping electrophysiological data in a heart chamber includes inserting a catheter having an electrode into the heart chamber. Electrophysiological data in the heart chamber is acquired with the electrode, and the position of the electrode is determined by using an electromagnetic field source external to the heart chamber. A geometrical representation of at least a portion of the heart chamber is created, and a three-dimensional map of the electrophysiological data is created and superimposed on the geometrical representation.

Flexible circuit coils

Disclosed is a system for determining a location and configuration of an expandable member. A flexible coil can be provided on a shape changing portion, such as an expandable portion, to measure a signal as the shape changes.

SYSTEMS, DEVICES AND METHODS FOR DRAINING AND ANALYZING BODILY FLUIDS

Systems, devices and methods for draining and analyzing bodily fluids are disclosed in which a drainage assembly is configured to prevent negative pressure build-up. The drainage assembly generally includes a catheter which may include a drainage lumen, a reservoir, a venting mechanism in fluid communication with the drainage lumen and a positive pressure lumen, and a controller. The venting mechanism may further include a valve which is configured to maintain a closed position, as well as a vent in fluid communication with the valve, where the venting mechanism is configured to inhibit wetting of the vent from fluid within the drainage lumen ...

Systems and methods for selective auto-retroperfusion along with regional mild hypothermia

Systems and methods for selective auto-retroperfusion along with regional mild hypothermia. In at least one embodiment of a system for providing a retroperfusion therapy to a venous vessel of the present disclosure, the system comprises a catheter for controlling blood perfusion pressure, the catheter comprising a body having a proximal open end, a distal end, a lumen extending between the proximal open end and the distal end, and a plurality of orifices disposed thereon, each of the orifices in fluid communication with the lumen, and at least one expandable balloon, each of the at least one expandable balloons coupled with the body, having an interior that is in fluid communication with the lumen, and adapted to move between an expanded configuration and a deflated configuration, and a flow unit for regulating the flow and pressure of a bodily fluid, and a regional hypothermia system operably coupled to the catheter, the regional hypothermia system operable to reduce and/or regulate a ...

POLYMERIC MARKER WITH HIGH RADIOPACITY FOR USE IN MEDICAL DEVICES

BALLOON CATHETER COMPRISING AN INFLATABLE BALLOON AND A CAPACITIVE SENSOR FOR MEASURING A DIAMETER OF THE BALLOON

DEVICE FOR DETECTING PROSTATE FEATURES

ТРЕХМЕРНОЕ ПРЕДСТАВЛЕНИЕ ВНУТРИСЕРДЕЧНОЙ АКТИВНОСТИ

Группа изобретений относится к медицине, а именно к медицинскому способу трехмерного представления электрической внутрисердечной активности и системе для его реализации. При этом осуществляют прием сигналов от катетера, который выполнен с возможностью введения в камеру сердца живого субъекта и содержит электроды для контакта с тканями в местоположениях внутри камеры сердца. Осуществляют дискретизацию значений напряжения сигналов. Вычисляют изогнутые трехмерные поверхности, описывающие электрическую активность ткани на электродах в периоды дискретизации в ответ на положения электродов и дискретизированные значения напряжения. Положения электродов представляют собой положения, проецируемые на плоскость. Вычисляют смещения перпендикулярно плоскости от проецируемых положений электродов. Приводят в соответствие изогнутые трехмерные поверхности в ответ на смещения перпендикулярно плоскости от проецируемых положений. Отображают трехмерные поверхности на дисплее в динамике по времени. Обеспечивается ...

Compartment Syndrome Monitoring Systems and Methods

Embodiments of a compartment monitor that can be implanted and left in situ to continuously (or semi-continuously) measure compartment pressures are presented. An exemplary monitor includes a pressure sensor adapted to be implanted in a compartment, a transmitter external to the compartment and coupled to the pressure sensor, and a receiver in communication with the transmitter to receive and process pressure data received from the transmitter. The monitor may also be configured to transmit measured pressure data to a networkable device. The networkable device can then communicate the patient's status and condition to a healthcare provider through a local area network (LAN) or wide area network (WAN). This communication allows the healthcare provider to remotely monitor a patient. The networkable device, or associated computing system, can record and display trends in the pressure data over time, and log the data to the patient's electronic health records.

Catheter, a balloon catheter and a method and apparatus for monitoring the transverse cross-section of a stoma

A balloon catheter ( 1 ) comprises a catheter ( 2 ) and a balloon ( 6 ) located on the distal end of the catheter. A pair of stimulating electrodes ( 15 ) for receiving a constant current stimulating signal when the balloon ( 6 ) is inflated with an electrically conductive medium and a plurality of sensing electrodes ( 16 ) for producing voltage response signals are located on the catheter ( 2 ). The voltage response signals are indicative of the values of the transverse cross-sectional area of the balloon ( 6 ) adjacent the sensing electrodes ( 16 ). A first lumen < 9 ) accommodates the inflating medium to and from the balloon ( 6 ), and a second lumen ( 19 ) accommodates electrically conductive wires ( 18 ) to the stimulating and sensing electrodes ( 15,16 ). A pressure sensing dement ( 21 ) is located in a protective housing ( 22 ) in the second lumen ( 19 ), and communicates through a communicating opening ( 26 ) in the protective housing ( 22 ) and through a communicating port ( 24 ) in the catheter ( 2 ) with a hollow interior region ( 7 ) of the balloon ( 6 ).

Methods and systems for determining vascular bodily lumen information and guiding medical devices

Methods and systems for determining information about a vascular bodily lumen are described. An exemplary method includes generating an electrical signal, delivering the electrical signal to a plurality of excitation elements in the vicinity of the vascular bodily lumen, measuring a responsive electrical signal from a plurality of sensing elements in response to the delivered electrical signal, and determining a lumen dimension. Specific embodiments include generating a multiple frequency electrical signal. Another embodiment includes measuring a plurality of responsive signals at a plurality of frequencies. Still other embodiments include using spatial diversity of the excitation elements. Yet other embodiments use method for calibration and de-embedding of such measurements to determine the lumen dimensions. Diagnostic devices incorporating the method are also disclosed, including guide wires, catheters and implants. The methods and systems described herein are advantageous as they do not include injecting a second fluid for the measurements.

Systems and methods for analysis and treatment of a body lumen

A catheter for placement within a body lumen, the catheter including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end, at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a lumen-expanding inflatable balloon disposed about a portion of the conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located within the balloon; and, at least one elongate arm connected to the conduit and positioned within the balloon, the at least one elongate arm radially translatable with respect to the conduit, and wherein at least one of the transmission output and transmission input is coupled to the elongate arm.

Method and apparatus for performing transesophageal cardiovascular procedures

An apparatus for performing a transesophageal cardiovascular procedure includes an elongated tubular main access device having a first lumen with an open proximal end and a distal side opening, and a second lumen with a rigid outer wall and a collapsible inner wall. The second lumen is adapted to receive an elongated probe or surgical device. The apparatus further includes an inflatable sealing means on the outside of the main access device above and below the side opening, and a first fluid conduit extending along the main access device for inflating the sealing means so that when the main access device is inserted into a patient's esophagus and the sealing means are inflated. The portion of the esophagus opposite the side opening is isolated from the remainder of the esophagus above and below the side opening.

System for continuous measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space, and use thereof

The present invention relates to a new system for measuring, recording and monitoring the splanchnic tissue perfusion and the pulmonary physiological dead space in an automated way, both continuously and intermittently, and in real time, which is easy to manage and generates information easy to interpret. Said system comprises at least four measuring devices of medical parameters, connected to a device receiving, converting, storing, integrating, processing, and allowing the management and display of the data recorded in the measurements and the parameters estimated by the same. For this purpose, said device comprises a specific computer program of estimation of parameters related to the measurement of the splanchnic tissue perfusion and the pulmonary physiological dead space, from the data derived from the measuring devices. Likewise, the present invention is related to the use of a device for measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space.

Apparatus and methods for treating obstructions within body lumens

Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.

System and method for mapping gastro-intestinal electrical activity

A gastro-electrical activity mapping system and comprises a catheter insertable through a natural orifice into the gastro-intestinal (GI) tract and comprising an array of electrodes for contacting an interior surface of a section of the GI tract to detect electrical potentials at multiple electrodes, and a signal analysis and mapping system arranged to receive and process electrical signals from multiple electrodes of the array and spatially map GI smooth muscle electrical activity as an activation time map, a velocity map, or an amplitude map, which may be in the form of contour plots and may be mapped on an anatomical computer model of at least the section of the GI tract and may be animated. A GI mapping method and catheter are also claimed.

DETECTING AND TREATING NERVOUS SYSTEM DISORDERS

Some embodiments of a mapping device may be capable of passing through cerebral veins and other cerebrovascular spaces to provide electrophysiological mapping of the brain. These embodiments of the device may also be capable of providing, simultaneously or separately, ablation energy or other treatments to targeted brain tissue. In such circumstances, a user may be enabled to analyze an electrophysiological map of a patient's brain and, at the same time or within a short time period before or after the mapping process, may be enabled to apply ablation energy for treatment of a central nervous system disorder. Such treatment may be accomplished without the use of invasive surgery in which the brain is accessed through an opening in the patient's cranium. 1. A method of using a catheter device to provide intravenous brain mapping from within one or more cerebral veins , comprising:advancing a distal tip portion of a brain mapping catheter device through a patient's vein that extends below the patient's head to a position within one or more cerebral veins proximal to brain tissue within the patient's head, wherein the brain mapping catheter device accesses the one or more cerebral veins without surgical access through an opening in the patient's cranium; andusing one or more electrodes positioned along the distal tip portion of the brain mapping catheter device to detect electrophysiological signals in a portion of the brain tissue while the one or more electrodes remain disposed within the one or more cerebral veins and while a proximal portion of the brain mapping catheter device resides external to the patient.2. The method of claim 1 , further comprising electrically coupling at least one component of the proximal portion of the brain mapping catheter device to an electrophysiological mapping control and display system.3. The method of claim 2 , wherein the brain mapping catheter device comprises a flexible elongated body having an internal conduit through which ...

Systems and Methods for Visualizing Ablated Tissue

Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue includes a catheter having an expandable balloon at a distal end, an illumination device positioned within the balloon for propagating light from an external light source for illuminating a tissue being treated to excite native nicotinamide adenine dinucleotide hydrogen (NADH) in the tissue, and an imaging device positioned within the balloon for detecting fluorescence from the illuminated tissue, the imaging device being configured to communicate detected NADH fluorescence to an external fluorescence camera. 1. A system for imaging tissue comprising:a catheter having an expandable balloon at a distal end;an illumination device positioned within the balloon for propagating light from an external light source for illuminating a tissue being treated to excite native reduced nicotinamide adenine dinucleotide (NADH) in the tissue; andan imaging device positioned within the balloon for detecting fluorescence from the illuminated tissue, the imaging device being configured to communicate detected NADH fluorescence to an external fluorescence camera.2. The system of further comprising an ablation device for ablating the tissue.3. The system of claim 1 , wherein the tissue being treated is heart tissue.4. The system of further comprising a display system connected to the camera for generating an image of the illuminated tissue based on the detected NADH fluorescence.5. The system of claim 4 , wherein in the image tissue that was effected by a treatment is illustrated as having less fluorescence than tissue not affected by the treatment6. The system of further comprising a dichroic mirror and a plurality of filters for conditioning light from the light source and light reflected by the tissue.7. A system for imaging tissue comprising:a catheter system configured to position an illumination device and an imaging device in proximity to a tissue;an ablation device ...

Method and apparatus for performing transesophageal cardiovascular procedures

An apparatus for performing a transesophageal cardiovascular procedure includes an elongated tubular main access device having a first lumen with an open proximal end and a distal side opening, and a second lumen with a rigid outer wall and a collapsible inner wall. The second lumen is adapted to receive an elongated probe or surgical device. The apparatus further includes an inflatable sealing means on the outside of the main access device above and below the side opening, and a first fluid conduit extending along the main access device for inflating the sealing means so that when the main access device is inserted into a patient's esophagus and the sealing means are inflated. The portion of the esophagus opposite the side opening is isolated from the remainder of the esophagus above and below the side opening.

DEVICE FOR SENSING A TARGET CHEMICAL AND METHOD OF ITS MAKING

The present invention relates to a device for sensing a target chemical. The device includes a flexible, non-planar substrate; a printed, solid-state sensing element comprising a chemical sensing material which produces an electrical signal upon interaction with the target chemical; a first printed electrode comprising a first conductive composition; and a second electrode comprising a second conductive composition. The first and second electrodes are electrically isolated from one another, and one or both of the first and second electrodes is in electrical contact with said sensing element. The first and second electrodes and the sensing element collectively form an electrochemical sensor which is coupled to the flexible, non-planar substrate. Medical devices comprising the device of the present invention and methods of making a device for sensing a target chemical are also disclosed. 1. A device for sensing a target chemical comprising:a flexible, non-planar substrate;a printed, solid-state sensing element comprising a chemical sensing material which produces an electrical signal upon interaction with the target chemical;a first printed electrode comprising a first conductive composition; anda second electrode comprising a second conductive composition, wherein said first and second electrodes are electrically isolated from one another, and one or both of the first and second electrodes is in electrical contact with said sensing element, wherein said first and second electrodes and said sensing element collectively form an electrochemical sensor, which is coupled to said flexible, non-planar substrate.2. The device according to claim 1 , wherein the first printed electrode is in electrical contact with said sensing element.3. The device according to claim 1 , wherein both the first and second electrodes are in electrical contact with said sensing element.4. The device according to claim 1 , wherein the second electrode is printed onto the substrate.5. The device ...

Catheter balloon methods and apparatus employing sensing elements

An apparatus for medical diagnosis and/or treatment is provides. The apparatus includes a flexible substrate forming an inflatable body and a plurality of sensing elements disposed on the flexible substrate. The plurality of sensing elements are disposed about the inflatable body such that the sensing elements are disposed at areas of minimal curvature of the inflatable body in a deflated state.

SURGICAL TISSUE MONITORING SYSTEM

A tissue monitoring system includes an introducer having an inflatable section and a plurality of electrodes disposed thereon. The electrodes are alternatively connected to an electrode contact system which includes at least one signal line and at least one measurement line for taking readings about a circumferential segment of tissue encompassed by the electrodes. 1. A method of monitoring tissue comprising:placing an introducer having an inflatable section and a plurality of electrodes disposed about the inflatable section adjacent to a section of tissue;distending the first inflatable section of the introducer;imposing an electrical signal on the tissue using a subset of the plurality of electrodes selected for an electrode contact system;measuring a resulting potential with the subset of the plurality of electrodes of the electrode contact system; andshifting the electrode contact system to alternate placement of the electrode contact system within the tissue.2. The method of claim 1 , wherein the step of shifting the electrode contact system includes electronically shifting each contact of the electrode contact system to encompass a different subset of the plurality of electrodes.3. The method of claim 2 , wherein electronically shifting each contact includes shifting each contact to an adjacent electrode on the inflatable section of the introducer.4. The method of claim 1 , wherein the introducer further includes a shaft extending through the introducer claim 1 , and wherein the step of shifting the electrode contact system includes rotating the shaft to shift the electrode contact system clockwise or counterclockwise around a circumferential segment of the tissue.5. The method of claim 1 , further comprising repeating the step of shifting the electrode contact system until an entire circumference of the tissue is characterized.6. The method of claim 1 , wherein the step of imposing an electrical signal includes attaching two electrodes of the subset of the ...

MEDICAL DEVICE WITH SLOTTED MEMORY METAL TUBE

A series of medical instruments can be made with the use of shape memory tube with a transformation temperature that is above or below ambient temperature. In the first case, the material behaves with the shape memory effect and in the second case the behavior is superelastic. The wall of the tube has been provided with a plurality of slots in specific places, often near or at the distal end of the instrument, and in specific arrangements which allow local variations in diameter, shape, and/or length. These variations can either be caused by the memory effect during temperature change or by superelastic behavior during change of the mechanical influences on the memory metal by the surrounding material. 1. A medical instrument comprising:at least one memory metal tube programmed for memory effect or superelasticity and having in at least one section thereof a plurality of slots such that the slotted section is capable of expansion and contraction, said memory metal tube having an expandable section that is substantially filled by an elastically deformable polymer, which upon expansion in a tubular cavity plugs the cavity; anda delivery tube that surrounds at least the slotted section of the memory metal tube during delivery and which is partially removed from surrounding the slotted section of the memory metal tube by a relative longitudinal movement between the respective tubes.2. The instrument of being a retrieval basket for retrieving particles to be removed from the human body.3. The instrument of being a dilator to enlarge the diameter of collapsed or obstructed ducts claim 1 , veins claim 1 , arteries or other cavities in the human body.4. The instrument of being a reaming tool to cut parts off the wall of a cavity by rotational movement around the longitudinal axis of the instrument.5. The instrument of being an expansion tool that is expandable at a distal end to enlarge a body cavity.6. The instrument of wherein the slots in the memory metal tube extend to ...

PRESSURE SENSING SYSTEM AND METHOD

A device for detecting rhinitis in a human subject includes an inflatable member that, in a first state, is configured to be introducible into the nasal cavity of the human subject; an expansion member configured to expand the inflatable member to an expanded, second state within the nasal cavity such that the inflatable member abuts against the tissue of the nasal cavity, and a pressure sensing member configured to measure a pressure exerted on the inflatable member by the tissue of the nasal cavity. A system for detecting rhinitis and methods for analyzing tissue response pressure, detecting rhinitis, predicting the efficacy of a planned rhinitis treatment and evaluating the efficacy of a previous rhinitis treatment are provided. 1. A method for detecting rhinitis , comprising:introducing an inflatable member into a nasal cavity of a human subject;expanding the inflatable member within the nasal cavity such that the inflatable member abuts against a tissue of the nasal cavity;measuring a pressure exerted on the inflatable member by the tissue of the nasal cavity over a period of time to create a measured pressure curve; andanalyzing the measured pressure curve to detect rhinitis.2. A method for evaluating the efficacy of a previously performed rhinitis treatment , comprising:introducing an inflatable member into a nasal cavity of a human subject;expanding the inflatable member within the nasal cavity such that the inflatable member abuts against a tissue of the nasal cavity;measuring a pressure exerted on the inflatable member by the tissue of the nasal cavity over a period of time to create a measured pressure curve; andanalyzing the measured pressure curve to evaluate the efficacy of the previous rhinitis treatment.3. A method for predicting the efficacy of a rhinitis treatment , comprising:introducing an inflatable member into a nasal cavity of a human subject;expanding the inflatable member within the nasal cavity such that the inflatable member abuts against ...

Systems and methods for making and using medical ablation systems having mapping catheters with improved anchoring ability

A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.

SINGLE INJECTION METHODS FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS USING IMPEDANCE DEVICES

Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements. 1. A method for obtaining one or more conductance measurements using an impedance device , the method comprising the steps of:introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body;obtaining a first conductance measurement using the detector while the detector is surrounded by an outer sheath surrounding at least part of the impedance device, the first conductance measurement indicative of a fluid native to the mammalian luminal organ present within a lumen of the outer sheath;obtaining a second conductance measurement using the detector while the detector is surrounded by the outer sheath, the second conductance measurement indicative of a first injection of a first solution of a first compound through the lumen of the outer sheath;moving the impedance device and/or the outer sheath relative to one another so that the outer sheath no longer surrounds the detector;obtaining a third conductance measurement using the detector, the third conductance measurement indicative of the fluid native to the mammalian luminal organ;obtaining a fourth conductance measurement using the detector, the fourth conductance measurement indicative of a second injection of the ...

Biomarker Sampling in the Context of Neuromodulation Devices, Systems, and Methods

Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to biomarker sampling in the context of neuromodulation devices, systems, and methods. Some embodiments, for example, are directed to catheters, catheter systems, and methods for sampling biomarkers that change in response to neuromodulation. A system can include, for example, an elongated shaft and a neuromodulation and sampling assembly having a neuromodulation and a sampling element. 1. A system , comprising:a neuromodulation element configured to modulate nerves at or otherwise proximate to a renal artery of a patient;an elongated shaft having a first portion configured to be intravascularly positioned while the neuromodulation element modulates the nerves, and a second portion proximal to the first portion, the second portion configured to be extracorporeally positioned while the neuromodulation element modulates the nerves;an occlusion member extending around a segment of the first portion;a sampling port distal to the segment of the first portion;a sampling lumen extending from the sampling port toward the second portion;an inflation opening within the occlusion member; andan inflation lumen extending from the inflation opening toward the second portion.2. The system of claim 1 , further comprising an analyzer configured to analyze a biological sample from the patient for a biological parameter that changes in response to modulating the nerves.3. The system of wherein:the analyzer is operably connected to the second portion; andthe sampling lumen extends from the sampling port along the shaft to the analyzer.4. The system of claim 2 , further comprising a handle coupled to the second portion claim 2 , wherein the analyzer is carried by the handle.5. The system of wherein the analyzer includes an indicator configured to indicate a status of the biological parameter claim 2 , a ...

System and methods for locating and ablating arrhythomogenic tissues

The disclosure relates to a variety of systems and methods for sensing electrical events about a selected annulus region of the heart and for treating tissue in the selected annulus region. Wherein the system includes a first catheter that has an expandable member, an ablation element, and a lumen configured to allow a second catheter therethrough. The second catheter includes a distal section in a ring shape and a plurality of electrodes coupled around the ring. Optionally a second lumen can be included through the first catheter that allows for contrast media to be delivered to the distal end of the system. 120-. (canceled)21. A system for sensing electrical events about a selected intrabody annulus region and for treating tissue in the selected annulus region , comprising:a first catheter and a second catheter; a first handle assembly;', 'a first shaft having a first proximal end coupled to the first handle assembly, and a first distal end, the first shaft extending along a first axis;', 'a first lumen extending entirely through the first distal end of the first shaft along the first axis;', 'a second lumen extending entirely through the first distal end of the first shaft along the first axis;', 'an ablation element provided adjacent the first distal end of the first shaft;', 'an expandable member adjacent the first distal end; and', 'wherein the first lumen is adapted to receive the second catheter therethrough;, 'the first catheter comprising a second handle assembly;', 'a second shaft having a second proximal end coupled to the second handle assembly, and a second distal end, the second shaft of the second catheter extending along a second axis; and', 'a distal ring provided at the second distal end of the second shaft of the second catheter and oriented substantially perpendicular to the second axis of the second shaft of the second catheter, the distal ring having a plurality of discrete electrodes positioned about the distal ring of the second catheter., ' ...

MINIMALLY INVASIVE DETERMINATION OF COLLATERAL VENTILATION IN LUNGS

Minimally invasive methods, systems and devices are provided for qualitatively and quantitatively assessing collateral ventilation in the lungs. In particular, collateral ventilation of a target compartment within a lung of a patient is assessed by advancement of a catheter through the tracheobronchial tree to a feeding bronchus of the target compartment. The feeding bronchus is occluded by the catheter and a variety of measurements are taken with the use of the catheter in a manner which is of low risk to the patient. Examples of such measurements include but are not limited to flow rate, volume and pressure. These measurements are used to determine the presence of collateral ventilation and to quantify such collateral ventilation. 1. A method for determining the function or malfunction of an endobronchial prosthesis positioned within a lung passageway of a patient , said method comprising:occluding the lung passageway proximally of the endobronchial prosthesis;allowing the patient to breathe air without any markers; andmeasuring air flow or accumulation from the lung passageway over time wherein said measurement is correlative to the function or malfunction of the endobronchial prosthesis.2. A system for detecting collateral ventilation into a lung compartment in a patient , said system comprising:a catheter adapted to be introduced transtracheally to a bronchus leading to a target lung compartment;an occlusion member on a distal region of the catheter, said occlusion member being adapted to selectively occlude the bronchus; anda flow measurement sensor on the catheter to detect flow of air from the isolated compartment as the patient exhales.3. A system for detecting collateral ventilation into a lung compartment in a patient , said system comprising:a catheter adapted to be introduced transtracheally to a bronchus leading to a target lung compartment;an occlusion member or a distal region of the catheter, said occlusion member being adapted to selectively ...

CARDIAC CATHETER EMPLOYING CONFORMAL ELECTRONICS FOR MAPPING

An apparatus for medical diagnosis and/or treatment is provided. The apparatus includes a flexible substrate, an intermediate bus disposed on the flexible substrate, and a plurality of sensing elements disposed on the flexible substrate and coupled to the intermediate bus. The plurality of sensing elements and intermediate bus are disposed on the flexible substrate such that the sensing elements are disposed at areas of minimal strain of the flexible substrate. 1. An apparatus for medical diagnosis and/or treatment , the apparatus comprising:a flexible substrate;at least one intermediate bus disposed on the flexible substrate; and 'wherein each sensing element of the plurality of sensing elements is coupled to the at least one intermediate bus.', 'a plurality of sensing elements disposed in a close-packed array proximate to an end of the at least one intermediate bus,'}2. The apparatus of claim 1 , wherein the sensing elements are disposed at areas of minimal bending and/or flexing of the flexible substrate.3. The apparatus of claim 1 , wherein the flexible substrate is an adhesive patch or a bandage.4. The apparatus of claim 1 , wherein a measurement of the plurality of sensing elements provides a measure of an amount of contact between the inflatable body and a surface.5. The apparatus of claim 4 , wherein the surface is a portion of a tissue claim 4 , wherein a measurement from the plurality of sensing elements provides an indication of an arrhythmia condition of the tissue.6. The apparatus of claim 4 , wherein the surface is a portion of a tissue claim 4 , wherein a measurement from the plurality of sensing elements provides an indication of an artial fibrillation or a ventricular fibrillation of the tissue.7. The apparatus of claim 1 , wherein the flexible substrate forms an inflatable body claim 1 , and wherein a portion of the at least one intermediate bus is disposed about a distal region of the inflatable body.8. The apparatus of claim 7 , wherein the ...

Haptic system for balloon tipped catheter interventions

Embodiments of this invention include hand-held handles and systems for balloon-tipped catheter interventions that enable a user to appreciate a combination of palpable sensations as though his or her hand is actual anatomic tissue in situ in real time. The system may include a haptic handle coupled to the proximal end of the catheter where the haptic handle includes a balloon-shaped haptic interface that exhibits geometric characteristics reflecting an anatomy of the interventional balloon and provides tangible sensations representative of tissues surrounding the interventional balloon. Multiple sensors and actuators may be used to create a non-virtual, transparent experience communicated to a user with a three dimensional, volumetric haptic display. In one embodiment, the sensors are positioned about or within an inflatable balloon positioned at the distal aspect of an inserted catheter used to treat cardiac and vascular diseases such as coronary or peripheral vascular occlusion and ablation of cardiac tissue.

DEVICE WITH EXTERNAL PRESSURE SENSORS FOR ENHANCING PATIENT CARE AND METHODS OF USING SAME

A method for monitoring physiologic conditions of a patient includes inserting an esophageal or other suitable tube into the patient, the tube comprising a lumen having a proximal end, a distal end, and central portion, and a pressure sensor disposed about at least a portion of an outer surface of the lumen of the tube. The pressure sensor is capable of detecting a change in pressure when a force is exerted against the outer surface of the lumen. The tube is then positioned within the patient and an initial pressure reading of the pressure exerted against the pressure sensors disposed about the at least a portion of the outer surface of the lumen of the tube is taken. The method also includes monitoring changes in the initial pressure reading and, if needed, taking a second pressure reading. 1. A system for monitoring physiologic conditions of a patient , comprising:a medical device having an outer surface; anda pressure sensor disposed about at least a portion of the outer surface of the medical device; wherein the pressure sensor is capable of detecting a change in pressure when a force is exerted against the outer surface of the medical device.2. The system of claim 1 , wherein the medical device is selected from the group comprising an endotracheal tube claim 1 , an esophageal feeding tube claim 1 , a catheter claim 1 , or a dermal pad.3. The system of claim 2 , wherein the medical device is an endotracheal tube.4. The system of claim 3 , wherein the endotracheal tube comprises a lumen claim 3 , the lumen having a distal end claim 3 , a central portion claim 3 , and a proximal end.5. The system of claim 4 , wherein the medical device further comprises an inflatable cuff disposed between the central portion of the lumen and the distal end of the lumen.6. The system of claim 4 , wherein the pressure sensor is disposed on the outer surface of the central portion of the lumen.7. The system of claim 4 , wherein the pressure sensor is disposed on the outer surface of ...

VALVE APERTURE SIZING DEVICES AND METHODS

Valve aperture sizing devices and methods. In an exemplary method to size a valve aperture, the method comprises introducing at least part of a first device into a luminal organ at a valve aperture, the first device having a balloon positioned thereon, inflating the balloon within the valve aperture until a point of apposition is achieved, and obtaining a first valve aperture measurement based upon the point of apposition. 1. A method to size a valve aperture , comprising:introducing at least part of a first device into a luminal organ at a valve aperture, the first device having a balloon positioned thereon;inflating the balloon within the valve aperture until a point of apposition is achieved; andobtaining a first valve aperture measurement based upon the point of apposition.2. The method of claim 1 , further comprising:selecting a stent valve based upon the first valve aperture measurement.3. The method of claim 2 , further comprising:positioning the stent valve upon the balloon;re-introducing the at least part of the first device into the luminal organ; andre-inflating the balloon to place the stent valve within the luminal organ.4. The method of claim 3 , wherein the step of re-introducing is performed to re-introduce the at least part of the first device into the luminal organ at or near the valve aperture claim 3 , and wherein the step of re-inflating is performed to place the stent valve within the luminal organ at or near the valve aperture.5. The method of claim 3 , further comprising:positioning the stent valve around at least part of a second device;introducing the at least part of the second device into the luminal organ; andpositioning the stent valve within the luminal organ using the second device.6. The method of claim 1 , wherein the first device is configured as a catheter having a lumen therethrough and defining a suction/infusion port so that the lumen is in communication with the balloon claim 1 , and wherein the step of inflating is performed ...

Treating Heart Tissue

Some embodiments of a system or method for treating heart tissue can include a catheter device that provides a user with the ability to perform a number of heart treatment tasks (before, during, and after a cardiac surgery or a percutaneous coronary intervention). In particular embodiments, the catheter device can be used to (i) precondition heart muscle tissue before the heart is isolated from the circulatory system, (ii) deliver cardioplegia into the coronary sinus during the cardiac surgery when the heart is isolated from the circulatory system, and (iii) control the blood flow through the heart after the heart is reconnected with the circulatory system. In some embodiments, the catheter device can perform some or all of: (i) intermittently occluding the coronary sinus, (ii) delivering a treatment fluid into the coronary sinus, and (iii) monitoring a flow rate of blood passing from the coronary sinus to the right atrium. 1. (canceled)2. A method of using a coronary sinus occlusion catheter , comprising:engaging an inflatable balloon device of a distal tip portion of the coronary sinus occlusion catheter with an interior wall of the coronary sinus while the inflatable balloon device is in an inflated condition,detecting a first pressure at a first pressure sensor lumen that extends to a distal position that is distal of the inflatable balloon device;detecting a second pressure at a second pressure sensor lumen that extends to a proximal position that is proximal of the inflatable balloon device for detecting a second pressure; anddetermining a blood flow rate of blood passing along the distal tip portion in the coronary sinus from a region distal of the balloon device to a region proximal of the balloon device by comparing the first pressure detected at the first pressure sensor lumen and the second pressure detected at the second pressure sensor lumen.3. The method of claim 2 , further comprising intermittently adjusting the inflatable balloon device between a ...

METHODS FOR GENERATING LUMINAL ORGAN PROFILES USING IMPEDANCE

Methods to generate luminal organ profiles using impedance. One embodiment of such a method comprises the steps of introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position, measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities, moving the impedance device to a second position in the luminal organ, measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities, calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance, and constructing a profile of the treatment site. 1introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position;measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities;moving the impedance device to a second position in the luminal organ;measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities;calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance; andconstructing a profile of the treatment site based in part on the calculated first cross-sectional area and the calculated second cross-sectional area.. A method of creating a cross-sectional area profile of a targeted treatment site, the method comprising the ...

FUNCTIONAL ASSESSMENT AND TREATMENT CATHETERS AND METHODS FOR THEIR USE IN THE LUNG

Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed. 1. A functional assessment catheter for the lungs , said catheter comprising:a catheter shaft having a distal and a proximal end, and a central passage therebetween;a flow restrictive component disposed at the distal end of the catheter shaft, wherein the flow restrictive component has an expanded configuration and a contracted configuration; andan obturator disposed in the central passage and shiftable between a distally advanced position where it engages and elongates the flow restrictive component to cause the component to assume the contracted configuration, and a proximally retracted position where it allows the flow restrictive component to shorten and return to the expanded configuration.2. A functional assessment catheter as in claim 1 , wherein the flow restrictive component comprises a resilient scaffold and an elastomeric covering.3. A functional assessment catheter as in claim 2 , wherein the resilient scaffold comprises counter wound helical supports.4. A functional assessment catheter as in claim 1 , wherein a flow path is formed through the flow restrictive component so that gas may flow through the catheter shaft and through the flow restrictive component.5. A functional assessment catheter as in claim 4 , wherein the flow path comprises the central passage and an opening in a distal side of the elastomeric covering. ...

Body lumen junction localization

Devices, systems, and methods for the localization of body lumen junctions and other intraluminal structure are disclosed. Various embodiments permit clinicians to identify the locations of intraluminal structures and medical devices during non-surgical medical techniques, such as cardiac ablation, by determining the intralumen conductance and/or cross-sectional area at a plurality of locations within the body lumen

Abrading Balloon Catheter for Extravasated Drug Delivery

A method of extravasated drug delivery is disclosed, including inserting a catheter with a first balloon, a second balloon, and a third balloon positioned between the first and second balloons and having a wall with an abrasive outer surface, into a bodily cavity, inflating the first and second balloons to create a chamber therebetween, stimulating a flow of blood cells by inflating the third balloon until the abrasive outer surface abrades tissue, and delivering the agent to the chamber. A balloon catheter system is also provided including a balloon having a wall with an abrasive outer surface for abrading tissue, a catheter having a first lumen for supplying fluid to the balloon to inflate the balloon such that the abrasive surface stimulates a flow of blood cells, and a second lumen for supplying an agent to tissue. 1. A method of extravasated delivery of a therapeutic and/or diagnostic agent to tissue , comprising the steps of: a first balloon;', 'a second balloon; and', 'a third balloon positioned between the first and second balloons and having a wall with an abrasive outer surface;, 'inserting a catheter into a bodily cavity, said catheter comprising'}inflating the first and second balloons to create a chamber between the first balloon and the second balloon, wherein the boundaries of the chamber are defined by an inner surface of the cavity wall and the catheter;stimulating a flow of blood cells by repeatedly inflating and deflating the third balloon by supplying fluid to the third balloon such that the abrasive outer surface abrades tissue in the bodily cavity as the third balloon is repeatedly inflated and deflated; anddelivering the therapeutic and/or diagnostic agent to the chamber and external of the third balloon after stimulating the flow of blood cells.2. The method of claim 1 , wherein the abrasive outer surface comprises a mesh affixed to the wall of the third balloon.3. The method of claim 1 , wherein the first balloon and the second balloon each ...

Carotid Artery Occluding Apparatus with First and Second Occluding Balloons

An apparatus for preventing stroke by occluding blood flow through a right carotid artery and a left carotid artery of a patient is provided. The apparatus has a first occluding catheter that carries a first occluding balloon that has an inflated configuration that occludes either the right carotid artery or the left carotid artery. The apparatus also includes a second occluding catheter that carries a second occluding balloon that has an inflated configuration that occludes the other one of the right carotid artery or the left carotid artery that is not occluded by the first occluding balloon. An insertion device may also be present to allow for insertion of the first and second occluding catheters. 1. An apparatus for preventing stroke by occluding blood flow through a right carotid artery and a left carotid artery of a patient , comprising:a first occluding catheter that carries a first occluding balloon that has an inflated configuration that occludes either the right carotid artery or the left carotid artery; anda second occluding catheter that carries a second occluding balloon that has an inflated configuration that occludes the other one of the right carotid artery or the left carotid artery that is not occluded by the first occluding balloon.2. The apparatus as set forth in claim 1 , wherein the first occluding balloon is in the inflated configuration and is located in an innominate artery of the patient and occludes the right carotid artery and a right subclavian artery of the patient claim 1 , wherein the second occluding balloon is in the inflated configuration and is located in the left carotid artery and occludes the left carotid artery.3. The apparatus as set forth in claim 1 , wherein the first occluding balloon is in the inflated configuration and is located in the right carotid artery and occludes the right carotid artery and does not occlude a right subclavian artery of the patient claim 1 , and wherein the second occluding balloon is in the ...

Transducer interface system and method

A transducer interface system/method allowing conversion from an analog sensor input to a standardized analog output interface is disclosed. In some preferred embodiments the system/method permits a fiber optic pressure sensor to be interfaced to a standard patient care monitor (PCM) system using standardized Wheatstone Bridge analog interface inputs. Within this context the Wheatstone Bridge sensed output is defined by stimulus from the PCM and modulation of bridge element values by the conditioned output of an analog pressure sensor. The use of analog-to-digital-to-analog conversion in this transducer interface permits retrofitting of PCM devices having analog Wheatstone Bridge inputs with advanced patient monitoring sensors without the need for specialized modifications to the baseline PCM data collection framework. Methods disclosed herein include techniques to connect arbitrary types/numbers of analog sensors to traditional PCM systems without the need for PCM system hardware/software modifications.

TRACHEAL TUBE SENSOR DISPOSED ON PERMEABLE MEMBRANE

Various embodiments of an tracheal tube having a sensor coupled to a selectively permeable membrane are provided. In some embodiments, the membrane may be permeable to one or more blood gases and/or blood analytes. Certain embodiments of the endotracheal tube may be capable of deploying the sensor during intubation to sense one or more indicators of blood flow characteristics, such as a level of blood gases and/or blood analytes, in the respiratory tract. Embodiments of the present invention may include positioning of the sensor in a variety of suitable positions with respect to the permeable membrane, such as mounting the sensor to the underside of an inflatable permeable membrane. 120.-. (canceled)21. A tracheal tube system , comprising:a tubular body having a recess disposed therein and an open distal end for ventilating a patient;a cuff disposed around the tubular body above the open distal end and configured to be inflated to seal the cuff against a wall of a trachea;a sensor coupled to a membrane that is selectively permeable to an analyte or a gas, wherein the sensor is configured to measure a concentration of the analyte or the gas in the trachea, and wherein the recess receives the sensor during intubation and extubation; anda monitor coupled to the sensor and configured to receive a signal from the sensor and provide an output related to the concentration of the analyte or the gas in the trachea.22. The tracheal tube system of claim 21 , wherein the monitor comprises a display configured to display the output.23. The tracheal tube system of claim 22 , comprising an interface circuit coupled to the sensor and the monitor claim 22 , wherein the interface circuit is configured to process the signal from the sensor.24. The tracheal tube system of claim 21 , wherein the sensor comprises a carbon dioxide sensor.25. The tracheal tube system of claim 21 , wherein the sensor comprises an oxygen sensor.26. The tracheal tube system of claim 21 , wherein the sensor ...

Occlusion perfusion catheter

Catheters for occluding, visualizing, irrigating, evacuating, and delivering agents to a treatment area are disclosed. The catheters comprise a catheter body comprising five lumens, first and second occlusion balloons coupled to the catheter body, an optional space-occupying balloon coupled to the catheter body and disposed between the first and second occlusion balloons, and an optional visualization means that enables visualization between the first and second occlusion balloons. Methods for using these catheters are also disclosed. A method comprises inflating the first and second occlusion balloons, inflating the space-occupying balloon, allowing fluid to exit via an evacuation lumen, optionally irrigating or aspirating to facilitate fluid exit via said lumen, and delivering an agent to a treatment area via the agent lumen.

SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN

A system for analyzing a body lumen including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end; at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit; a spectrometer connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform diffuse reflectance spectroscopy, wherein the spectrometer emits at least one primary radiation signal of a wavelength having an absorption coefficient of between about 8 cmand about 10 cmwhen transmitted through a highly aqueous media; a controller system configured to calculate at least one of an extent, area, and volume of highly aqueous media based on the amount of absorption of the at least one primary radiation signal measured through the highly aqueous media by the spectrometer. 1a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end;at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit;{'sup': −1', '−1, 'a spectrometer connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform diffuse reflectance spectroscopy, wherein the spectrometer emits at least one primary radiation signal of a wavelength having an absorption coefficient of between about 8 cmand about 10 cmwhen transmitted through a highly aqueous media; and'}a controller system configured to calculate at least one of an extent, area, and volume of highly ...

BLOOD FLOW RATE MEASUREMENT SYSTEM

The present invention discloses a heat exchanging assembly with a body adaptable to a catheter for measuring blood flow rate with a supply system for providing the heat exchanging medium to the heat exchanging assembly at a constant temperature and constant flow rate. The heat exchanging assembly comprises a heat exchanging element, a plurality of temperature sensors, a sensor lumen and an inflation lumen. 1. A system for maintaining a heat-exchanging medium at a constant temperatur and at a constant flow rate comprising:a reservoir;a pump connected to said reservoir by a first path wherein said pump pumps heat-exchanging medium out of said reservoir;a cooling apparatus connected to said pump by a second path and connected to said reservoir by a third path wherein said cooling apparatus cools said heat-exchanging medium pumped out of said reservoir;a valve located in said third path wherein a first configuration of said valve allows said cooled heat-exchanging medium to flow along said third path to said reservoir and a second configuration of said valve redirects said cooled heat-exchanging medium from said third path to a fourth path;a catheter, connected to said valve by said fourth path; anda fifth path with a first end connected to said reservoir and a second end connected to said catheter wherein said cooled heat-exchanging medium flows from said catheter to said reservoir along said fifth path.2. The system of wherein said valve is located proximate said cooling apparatus to ensure said cooled heat-exchanging medium flowing to said catheter along said fourth path is at a stabilised cooled temperature.3. The system of wherein said cooling apparatus comprises a fan.4. The system of wherein said cooling apparatus comprises a peltier cooler.5. The system of wherein said pump comprises an electric pump connected to a power supply to circulate said heat-exchanging medium in said system.6. The system of wherein each of said first claim 1 , second claim 1 , third ...

MAP AND ABLATE CLOSED-LOOP COOLED ABLATION CATHETER

A system for performing mapping and ablation functions includes a catheter sized and shaped for vascular access. The catheter includes an elongate body extending between a proximal end and a distal end. A tip section positioned at the distal end of the catheter body and includes a proximal portion and a distal portion. One or more electrode structures are formed on an exterior surface of the tip section. The one or more electrode structures each includes a mapping electrode at the distal portion of the tip section and a contact pad electrically coupled to the mapping electrode. 1. A system for performing mapping and ablation functions , the system comprising:a catheter sized and shaped for vascular access and including an elongate body extending between a proximal end and a distal end;a tip section positioned at the distal end of the body, the tip section including a proximal portion and a distal portion; andone or more electrode structures on an exterior surface of the tip section, the one or more electrode structures each including a mapping electrode at the distal portion of the tip section and a contact pad electrically coupled to the mapping electrode.2. The system of claim 1 , wherein the tip section comprises an ablation electrode configured to deliver radio frequency (RF) energy for an RF ablation procedure claim 1 , and wherein the one or more electrode structures are on an exterior surface of the ablation electrode.3. The system of claim 2 , wherein the one or more electrode structures further includes an insulative base layer between each of the one or more electrode structures and the ablation electrode.4. The system of claim 2 , wherein the catheter includes at least one inner fluid lumen claim 2 , wherein the ablation electrode comprises an exterior wall that defines an open interior region within the ablation electrode claim 2 , and wherein the catheter system further comprises:a thermal mass within the open interior region; anda cooling chamber in ...

SURGICAL TECHNIQUE(S) AND/OR DEVICE(S)

One or more techniques and/or devices are disclosed for promoting standardization of the dissection of a portion of a patient's stomach, such as during laparoscopic sleeve gastrectomy (LSG), for example. In this way, LSG can be improved at least by allowing a surgeon and/or patient to choose a post surgery stomach size in a quantifiable manner. For example, a patient could discuss various stomach sizing options with their doctor and select the option believed to be most beneficial to the patient. Moreover, one or more techniques and/or devices are disclosed for decreasing tissue trauma while performing surgical stapling, such as during LSG. In this way, surgical procedures that implement stapling can be improved, as reduced tissue trauma generally accelerates healing time, among other things. For example, staples and/or staple cartridges may be designed to reduce pinching or pressure points along a staple line while achieving desired closure and/or hemostasis. 1. A device configured to promote standardizing tissue resection during sleeve gastrectomy comprising:a tube comprising one or more markings along at least some of a length of the tube;a balloon operatively coupled to one end of the tube, the balloon configured to block a surrounding orifice upon inflation; anda balloon inflation mechanism disposed along at least some of the length of the tube and configured to at least one of inflate or deflate the balloon.2. The device of claim 1 , comprising one or more secondary inflation channels disposed along at least some of the length of the tube and configured to at least one of provide or remove at least one of a gas claim 1 , a liquid claim 1 , or a solid to an area exterior to the tube.3. The device of claim 1 , the balloon inflation mechanism comprising a balloon inflation channel.4. The device of claim 3 , the balloon inflation channel configured to inflate the balloon based at least in part on providing at least one of a gas claim 3 , a liquid claim 3 , or a ...

ACCOUNTING FOR NON-UNIFORM LONGITUDINAL MOTION DURING MOVEMENT OF AN ENDOLUMINAL IMAGING PROBE

Apparatus and methods are provided including, while an endoluminal data-acquisition device is being moved through a lumen of a subject, acquiring a plurality of endoluminal data points of the lumen using the endoluminal data-acquisition device. At at least one location it is determined that an event occurred, the event causing the endoluminal data-acquisition device not to acquire a single endoluminal data point at the location. The endoluminal data points are displayed in a stack, in which the endoluminal data points are positioned at locations corresponding to relative locations within the lumen at which the endoluminal data points were acquired, and in which the event is accounted for. Other applications are also described. 1102-. (canceled)103. Apparatus comprising:an endoluminal data-acquisition device configured to acquire a plurality of endoluminal data points while moving through a lumen of a subject;a display; andat least one processor configured:to determine that, at at least one location, an event occurred, the event causing the endoluminal data-acquisition device not to acquire a single endoluminal data point at the location,to generate a stack of the endoluminal data points, in which the endoluminal data points are positioned at locations corresponding to relative locations within the lumen at which the endoluminal data points were acquired, and in which the event is accounted for, andto drive the display to display the stack.104. The apparatus according to claim 103 , wherein the processor is configured to drive the display to display a length scale in relation to the displayed stack of the endoluminal data points.105. The apparatus according to claim 103 , wherein the endoluminal data-acquisition device comprises an endoluminal imaging device that is configured to acquire a plurality of endoluminal images while the endoluminal imaging device is being moved through the lumen claim 103 , and wherein the processor is configured to generate the stack by ...

POLYMERIC MARKER WITH HIGH RADIOPACITY FOR USE IN MEDICAL DEVICES

High radiopacity is achieved in a polymeric marker by combining a polymeric resin, a powdered radiopaque agent having uniformly shaped particles of a specific particle size distribution and a wetting agent. The method to produce the marker calls for the blending and pelletization of these materials followed by extrusion onto support beading. The resulting supported tubing is subsequently cut to length with the beading still in place. After ejection of the beading remnant the marker is slipped into place on the device to be marked and attached by melt bonding. Marking of a guidewire allows lesions to be measured while the marking of balloon catheters allow the balloon to be properly positioned relative to a lesion. 117-. (canceled)18. A method of radiopaquely marking a medical device , comprising:providing a flexible polymeric radiopaque marker containing greater than 30 volume percent radiopaque particles, wherein such particles have an average diameter of at least 2 microns and a maximum diameter of about 20 microns;accurately positioning said marker on said medical device; andmelt bonding said marker in place.19. The method of claim 18 , further comprising disposing a length of heat shrink tubing about said accurately positioned marker and heating said tubing.20. The method of claim 18 , wherein said radiopaque particles comprise tungsten.21. The method of claim 18 , wherein said medical device comprises a balloon catheter and said marker is positioned on an inner member disposed within an expandable balloon.22. The method of claim 18 , wherein said medical device comprises a guidewire.23. The method of claim 22 , wherein a plurality of said markers are bonded to said guidewire.24. The method of claim 23 , wherein said markers are equally spaced relative to one another so as to function as a ruler under fluoroscopic inspection.25. The method of claim 23 , wherein said guidewire includes a radiopaque feature and wherein said markers are each spaced a preselected ...

CATHETER FOR MONITORING PRESSURE FOR MUSCLE COMPARTMENT SYNDROME

A multi-lumen catheter for monitoring intramuscular pressure having an elongated body configured and dimensioned for insertion into a compartment of a patient. The catheter has a pressure sensor to determine if excessive pressure is being applied. A sensor is in communication with the lumen to continuously measure pressure to provide continuous readings of intramuscular pressure. 116-. (canceled)17. A method for measuring intramuscular pressure within an orthopedic cast on a body of the patient for assessing muscle compartment syndrome , the method comprising the steps of:positioning a catheter having a lumen and a pressure sensor within the orthopedic cast so a distal portion of the catheter is retained within the cast and a proximal portion of the catheter is exposed from the cast;connecting the catheter to a pressure monitor;obtaining a first pressure reading of intramuscular pressure of a first muscle within the cast for assessing muscle compartment syndrome;transmitting the first pressure reading to an external monitor in communication with the catheter to indicate pressure, the indicated pressure informing if intramuscular pressure exceeds a threshold pressure; andleaving the catheter within the cast for an extended period of time to obtain multiple pressure readings over the extended period of time;wherein connection to a pressure monitor occurs without removing the cast.18. The method of claim 17 , further comprising the step of creating a simultaneous pulse-oximeter reading to determine when to appropriately surgically intervene.19. (canceled)20. The method of claim 17 , further comprising the step of inserting a second catheter having a lumen and a pressure sensor to obtain a pressure reading of a second muscle within the cast to assess muscle compartment syndrome in the second muscle claim 17 , a proximal portion of the second device extending external of the cast to be exposed from the cast.21. The method of claim 17 , wherein the cast is a foot cast.22. ...

INTRAUTERINE ACCESS CATHETER FOR DELIVERING AND FACILITATING OPERATION OF A MEDICAL APPARATUS FOR ASSISTING PARTURITION

A system for augmenting uterine forces includes a medical apparatus having a balloon body that transitions between a compacted state and an expanded state, a catheter that receives the medical apparatus and obtains electrical signals indicative of intrinsic uterine contractions, and a controller coupled to the catheter to receive the electrical signals, and to a source of an agent. The controller processes the electrical signals to detect an onset of an intrinsic uterine contraction, an increase in uterine contraction forces, or a decrease in uterine contraction forces. In response to a detection of an onset of an intrinsic uterine contraction or an increase in uterine contraction forces, the controller causes an agent to be delivered from the agent source to the balloon body to expand the balloon body. In response to a detection of a decrease in uterine contraction forces, the controller causes agent to discharge from the balloon body to collapse the balloon body. 1. A system for augmenting expulsive uterine forces towards a cervical canal during delivery of a fetus from a uterus , the system comprising:a medical apparatus having a balloon body configured to transition between a compacted state and an expanded state;a catheter configured to receive the medical apparatus and obtain electrical signals indicative of intrinsic uterine contractions; and process the electrical signals to detect one of an onset of an intrinsic uterine contraction, an increase in uterine contraction forces, and a decrease in uterine contraction forces,', 'in response to either of a detection of an onset of an intrinsic uterine contraction or an increase in uterine contraction forces, cause agent to be delivered from the agent source to the balloon body to at least partially expand the balloon body, and', 'in response to a detection of a decrease in uterine contraction forces, cause agent to discharge from the balloon body to at least partially collapse the balloon body., 'a controller ...

METHOD AND APPARATUS FOR PERFORMING TRANSESOPHAGEAL CARDIOVASCULAR PROCEDURES

An apparatus for performing a transesophageal cardiovascular procedure includes an elongated tubular main access device having a first lumen with an open proximal end and a distal side opening, and a second lumen with a rigid outer wall and a collapsible inner wall. The second lumen is adapted to receive an elongated probe or surgical device. The apparatus further includes an inflatable sealing means on the outside of the main access device above and below the side opening, and a first fluid conduit extending along the main access device for inflating the sealing means so that when the main access device is inserted into a patient's esophagus and the sealing means are inflated. The portion of the esophagus opposite the side opening is isolated from the remainder of the esophagus above and below the side opening. 110.-. (canceled)11. An apparatus for performing a minimally invasive procedure , the apparatus comprising:a first lumen configured to traverse a portion of a patient's esophagus, wherein the first lumen includes an open proximal end and a side opening in a distal end, wherein the opening is configured to be adjacent the patient's esophagus;a second lumen configured to receive any of a device and probe, wherein the second lumen includes a portion configured to direct the any of the device and the probe through the side opening in the distal end of the first lumen; andmeans for generating an opening in the patient's esophagus through the opening in the distal end of the first lumen to thereby provide access to the patient's intra-thoracic cavity from the esophagus, wherein the means for generating the opening is insertable into the second lumen.12. The apparatus of claim 11 , wherein the second lumen is configured to receive the device and to direct the device through the opening in the distal end of the first lumen and through the opening in the patient's esophagus into a intra-thoracic cavity of the patient claim 11 , and wherein the device is configured to ...

ACCESSORY TO ALLOW SENSING AT BALLOON INTERFACE

A device, system and method for temperature-based lesion formation assessment and mapping functionality using an accessory usable with an over-the-wire balloon catheter. The device may include a first annular element, a plurality of wires coupled to the first annular element, and a second annular element, the plurality of wires passing from the first annular element through the second annular element and into an elongate wire conduit coupled to the second annular element. At least one of the plurality of wires may include at least one temperature sensor and/or at least one mapping electrode. The first annular element coupled to an outer surface of a sheath. As a balloon catheter is advanced out of the sheath lumen, the distal tip of the catheter engages the second annular element and pushes the wires out of the sheath lumen, everting them over the balloon of the catheter. 1. An accessory for a medical device , the accessory comprising:a first annular element;a plurality of wires coupled to the first annular element; anda second annular element, the plurality of wires passing from the first annular element through the second annular element.2. The accessory of claim 1 , further comprising an elongate wire conduit coupled to the second annular element claim 1 , the plurality of wires passing through the second annular element and into the wire conduit.3. The accessory of claim 1 , wherein at least one of the plurality of wires includes at least one of a temperature sensor and a mapping electrode.4. The accessory of claim 3 , wherein at least one of the plurality of wires further includes a reference electrode.5. The accessory of claim 3 , wherein each of the plurality of wires includes at least one temperature sensor and at least one mapping electrode.7. The accessory of claim 1 , wherein the accessory further includes a sheath having a distal portion claim 1 , a proximal portion claim 1 , and a lumen extending between the distal portion and the proximal portion.9. ...

CATHETER FOR MONITORING UTERINE CONTRACTION PRESSURE

A multi-lumen catheter for monitoring uterine contraction pressure having an elongated body configured and dimensioned for insertion into a bladder of a patient, the catheter having a first lumen, a second lumen, and a first balloon at a distal portion, the first lumen communicating with the first balloon. The second lumen communicates with the bladder to remove fluid from the bladder. The first balloon is filled with a gas to form along with the first lumen a gas filled chamber to monitor pressure within the bladder to thereby monitor uterine contraction pressure of the patient. 120- (canceled)21. A system for monitoring uterine contraction pressure via measuring bladder pressure , the system comprising a catheter having an elongated body configured and dimensioned for insertion into a bladder of a patient , the catheter having a first lumen , a second lumen , and a first balloon at a distal portion , the first lumen communicating with the first balloon , and the second lumen having an opening communicating with the bladder to remove fluid from the bladder through the second lumen , the first balloon filled with a gas to form along with the first lumen a gas filled chamber to monitor pressure within the bladder to thereby monitor uterine contraction pressure of the patient , and a sensor to measure pressure in response to deformation of the balloon , the pressure sensor measuring pressure of the bladder to provide readings of bladder pressure.22. The system of claim 21 , wherein the pressure sensor continuously communicates with an external monitor to visually display pressure readings claim 21 , the pressure sensor providing continuous pressure measurements throughout its duration of insertion without requiring infusion of water into the bladder.23. The system of claim 21 , wherein the gas filled chamber is a closed system.24. The system of claim 21 , further comprising a temperature sensor to measure maternal core body temperature.25. The system of claim 21 , ...

SENSING AND MAPPING CATHETER FOR GUIDING AND SUPPORTING BALLOON CATHETER

A catheter configured to guide and support a balloon catheter for use in and around a pulmonary vein and its ostium, has an elongated shaft and a distal assembly, the elongated shaft including a proximal portion with a first flexibility and a distal portion including a second flexibility greater than the first flexibility, the distal assembly including an elbow portion and a generally circular portion generally transverse to the longitudinal axis, the generally circular portion including a third flexibility greater than the second flexibility. Single axis location sensors and sensing ring electrodes are carried on the generally circular portion. 1. An electrophysiology catheter , comprising:an elongated shaft defining a longitudinal axis of the catheter, the shaft including a proximal portion with a first flexibility and a distal portion including a second flexibility greater than the first flexibility;a distal assembly including an elbow portion and a generally circular portion generally transverse to the longitudinal axis, the generally circular portion including a third flexibility greater than the second flexibility;a single axis sensor situated in the generally circular portion; anda ring electrode situated on the generally circular portion.2. The catheter of claim 1 , wherein the elongated shaft includes a hypotube with a lumen.3. The catheter of claim 2 , wherein the hypotube is coextensive with the proximal portion of the shaft.4. The catheter of claim 3 , further including a preformed support member with shape memory that extends at least through the distal assembly claim 3 , wherein a distal end of the preformed support member is received in the lumen of the hypotube.5. The catheter of claim 1 , further including a preformed support member with shape memory that extends at least through the distal assembly.6. The catheter of claim 5 , wherein the preformed support member includes a proximal portion that extends through the shaft.7. The catheter of claim 5 ...

SYSTEMS AND METHODS FOR ENDOBRONCHIAL DIAGNOSTICS

Methods and systems for accessing and diagnosing diseased lung compartments are disclosed. Methods may comprise introducing a diagnostic catheter with an occluding member at its distal end into a lung segment; inflating the occluding member to isolate the lung compartment; and performing a diagnostic procedure with the catheter. The proximal end of the diagnostic catheter is configured to be attached to a console. Methods may also include allowing air to enter the lung compartment through the passage in the catheter while the patient is inhaling and blocking air from being expelled from the lung compartment through the catheter passage while the patient is exhaling by using a one-way flow element adapted to be disposed within or in-line with the passage of the catheter so that flow in a proximal-to-distal direction is allowed and flow in a distal-to-proximal direction is inhibited or prevented. 1. A method of assessing the functionality of a lung compartment in a patient , the method comprising:introducing a diagnostic catheter into the lung compartment, wherein the diagnostic catheter comprises a distal end, an occluding member at the distal end, and a proximal end configured to be attached to a console;inflating the occluding member to isolate the lung compartment;{'sub': '2', 'measuring COconcentration within the isolated lung compartment over time; and'}{'sub': '2', 'determining whether collateral ventilation is present in the isolated lung compartment based on the measured COconcentration within the isolated lung compartment over time.'}2. The method of claim 1 , wherein determining whether collateral ventilation is present in the isolated lung compartment comprises determining that no collateral ventilation is present if the COconcentration within the isolated lung compartment plateaus over time.3. The method of claim 1 , wherein determining whether collateral ventilation is present in the isolated lung compartment comprises determining that collateral ...

METHODS AND SYSTEMS FOR DETERMINING COLLATERAL VENTILATION

Methods and systems for determining collateral ventilation are disclosed. Methods may comprise introducing a diagnostic catheter into a lung compartment via an assisted ventilation device, inflating the occluding member to isolate the lung compartment, and performing a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device. The diagnostic procedure comprises determining an exhaled volume from the isolated lung compartment over a predetermined period of time while the patient is ventilated via the assisted ventilation device. The presence collateral ventilation may be determined based on the exhaled volume from the isolated lung compartment over the predetermined period of time. 1. A method of determining collateral ventilation in a patient , the method comprising:introducing a diagnostic catheter into a lung compartment via an assisted ventilation device, wherein the diagnostic catheter comprises a distal end comprising an occluding member and a proximal end configured to be attached to a console;inflating the occluding member to isolate the lung compartment; andperforming a diagnostic procedure with the catheter while the patient is ventilated via the assisted ventilation device, wherein data generated from the diagnostic procedure are displayed on the console;wherein the diagnostic procedure comprises determining an exhaled volume from the isolated lung compartment over a predetermined period of time while the patient is ventilated via the assisted ventilation device and determining whether collateral ventilation is present in the isolated lung compartment based on the exhaled volume from the isolated lung compartment over the predetermined period of time.2. The method of claim 1 , wherein determining whether collateral ventilation is present in the isolated lung compartment comprises determining that no collateral ventilation is present if the exhaled volume from the isolated lung compartment over the ...

SYSTEMS, METHODS, AND APPARATUS FOR ESOPHAGEAL PANOMETRY

Systems, methods, and apparatus for esophageal panometry are provided. An example method includes capturing measurement data including an area and a pressure of an esophageal body via a measurement device positioned with respect to the esophageal body; generating representations of the exported measurement data; analyzing the measurement data to determine esophageal reactivity based on the area and pressure; assessing esophageal function based on the determined esophageal reactivity; and outputting an indication of esophageal function. 1. A method comprising:capturing measurement data including an area and a pressure of an esophageal body via a measurement device positioned with respect to the esophageal body;exporting the measurement data for analysis;generating representations of the exported measurement data;analyzing the measurement data to determine esophageal reactivity based on the area and pressure;assessing esophageal function based on the determined esophageal reactivity; andoutputting an indication of esophageal function.2. The method of claim 1 , wherein the measurement device includes an inflatable balloon position with respect to the esophageal body to trigger a physical reaction by conforming to available space in the esophageal body.3. The method of claim 2 , wherein a distension of the balloon and a physiological response to the distension are indicative of a health condition.4. The method of claim 3 , wherein the disease includes at least one of stricture claim 3 , eosinophilic esophagitis claim 3 , or achalasia.5. The method of claim 1 , wherein the measurement device is configured to measure a shape of the esophageal body over a period of time to evaluate a change in the area and pressure of the esophageal body over the period of time.6. The method of claim 1 , wherein the measurement device is configured to measure a plurality of cross-sectional areas and a plurality of pressures of the esophageal body.7. The method of claim 1 , wherein the ...

ENDOTRACHEAL TUBE APPARATUS

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface. Conductive electrodes are formed on the endotracheal tube. The conductive electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. At least wireless sensor is formed on the endotracheal tube, and is configured to wirelessly transmit information to a processing apparatus. 1. A method , comprising:providing an endotracheal tube having an exterior surface and at least four electrodes on the exterior surface;monitoring at least one nerve of a patient using the electrodes, wherein the monitoring includes sending, by the electrodes, at least two channels of monitoring signals to a multi-channel nerve integrity monitor device; andidentifying, with the multi-channel nerve integrity monitor device, a subset of the at least two channels to display.2. The method of claim 1 , and further comprising:sending, by the electrodes, at least four channels of monitoring signals to the multi-channel nerve integrity monitor device.3. The method of claim 1 , and further comprising:sending, by the electrodes, at least six channels of monitoring signals to the multi-channel nerve integrity monitor device.4. The method of claim 1 , and further comprising:carrying the monitoring signals from the electrodes to the multi-channel nerve integrity monitor device with a plurality of conductors.5. The method of claim 1 , wherein the identifying the subset of the at least two channels comprises identifying one of the channels having a best one of the monitoring signals.6. The method of claim 1 , wherein the identifying the subset of the at least two channels comprises identifying one of the channels having a largest one of the monitoring signals.7. The method of claim 1 , and further comprising:positioning at least a portion of the endotracheal tube in a region of a trachea of the ...

APPARATUS AND METHOD FOR INTRA-CARDIAC MAPPING AND ABLATION

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a Maze procedure. The location of the ports and valves is based on using the convective cooling effect of the blood flow. The mapping can be performed by a catheter-deployed expandable net or a scanning catheter. The same net or catheter can also perform the ablation procedure. 1. (canceled)2. A method comprising:providing a structure and a plurality of elements arranged on the structure;activating at least a group of elements in the plurality of elements to generate heat, each element in the group of elements activated to generate heat sufficient to cause an increase in temperature above blood temperature but insufficient to cause tissue ablation;displaying a representation of a first spatial distribution of at least the group of elements; anddisplaying, for each particular element in the group of elements, respective information related to the heat generated by the activation of the particular element.3. The method of claim 2 , comprising displaying claim 2 , for each particular element in the group of elements claim 2 , the respective information related to the heat generated by the activation of the particular element at least proximate a location of the particular element in the displayed first spatial distribution of at least the group of elements.4. The method of claim 2 , comprising displaying all of the respective information for all elements in the group of elements according to a second spatial distribution claim 2 , the second spatial distribution corresponding to the first spatial distribution of at least the group of elements.5. The method of claim 2 , comprising displaying claim 2 , for each particular element in the group of elements claim 2 , the respective information related to the heat ...

A METHOD AND APPARATUS FOR MONITORING THE DEGREE OF OPENING OF THE CERVIX PRIOR TO THE ONSET OF LABOUR

A balloon catheter () of apparatus () for monitoring ripening of a cervix () in a female subject prior to the onset of labour in a pregnancy comprises a cervix engaging balloon located distally on a catheter (). The balloon () is located in the cervix () and inflated with air by a syringe () to a pressure of approximately 80 mmHg. As the cervix () commences to ripen an opening () extending through the cervix () increases in volume thus resulting in a fall in pressure in the cervix engaging balloon (). A microprocessor () in a housing on the catheter () monitors the pressure in the balloon at predetermined time intervals and determines the volume of the opening () extending through the cervix () from a look-up table. A communications module () in the housing transmits a signal at the end of each predefined time period indicative of the state of the cervix () for reception by a smart mobile phone which is configured by an app to display a representation of the current state of the cervix (). 1169-. (canceled)170. Apparatus for monitoring the degree of opening of the cervix in a female mammal , the apparatus comprising an inflatable first balloon configured for locating in the cervix , a pressure sensing means for monitoring a pressure indicative of the pressure of a compressible inflating medium in the first balloon , and a means for determining the degree of opening of the cervix from the pressure of the inflating medium monitored by the pressure sensing means , and for producing a signal indicative of the degree of opening of the cervix.171. Apparatus as claimed in in which the first balloon is of length to extend through the length of the cervix.172. Apparatus as claimed in in which a retaining means is provided for retaining the inflating medium in the first balloon after it has been inflated in the cervix to a first predefined pressure claim 170 , and preferably claim 170 , the retaining means comprises a first valve claim 170 , and preferably claim 170 , the ...

ENDOTRACHEAL TUBE APPARATUS

An apparatus for monitoring EMG signals of a patient's laryngeal muscles includes an endotracheal tube having an exterior surface and a first location configured to be positioned at the patient's vocal folds. A first electrode is formed on the exterior surface of the endotracheal tube substantially below the first location to receive EMG signals primarily from below the vocal folds. A second electrode is formed on the exterior surface of the endotracheal tube substantially above the first location to receive EMG signals primarily from above the vocal folds. The first and second electrodes are configured to receive the EMG signals from the laryngeal muscles when the endotracheal tube is placed in a trachea of the patient. 1. An apparatus for monitoring EMG signals of a patient's laryngeal muscles , comprising:an endotracheal tube having an exterior surface; anda plurality of conductive electrodes printed on the exterior surface along a posterior side of the endotracheal tube, wherein the conductive electrodes are laterally offset and not substantially longitudinally offset, wherein an anterior side opposite the posterior side is substantially free from conductive electrodes.2. The apparatus of claim 1 , wherein the posterior side of the endotracheal tube is configured to be positioned along a posterior trachea of the patient.3. The apparatus of claim 1 , wherein the anterior side is completely free from conductive electrodes.4. The apparatus of claim 3 , wherein the posterior side of the endotracheal tube is configured to be positioned along a posterior trachea of the patient claim 3 , and wherein the anterior side of the endotracheal tube is configured to be positioned along an anterior trachea of the patient.5. The apparatus of claim 4 , and further comprising a cuff inflating lumen formed in the anterior side of the endotracheal tube.6. The apparatus of claim 1 , wherein the conductive electrodes extend longitudinally along a length of the tube and are spaced ...

Medical-mapping device

A medical-mapping device includes an elongated electrode-support assembly having spaced-apart electrodes configured to be maneuverable, at least in part, into, and along, a confined space of a patient. The spaced-apart electrodes are configured to be selectively movable between a storage position and a deployment position.

MEASURING LUNG FUNCTION AND LUNG DISEASE PROGRESSION AT A LOBAR/SEGMENTAL LEVEL

A method for determining lung function in a patient is disclosed, in which a multi-lumen catheter with an expandable occluding element at its end is used to isolate a targeted lung compartment, and respiratory characteristics at the targeted lung compartment are measured over multiple respiratory cycles. The relation between various characteristics of the respiratory cycle is used to determine compliance of lung tissue within the targeted lung compartment.

CATHETER FOR MONITORING INTRAUTERINE PRESSURE TO PROTECT THE FALLOPIAN TUBES

A multi-lumen catheter for monitoring intrauterine pressure comprising an elongated body configured and dimensioned for insertion into a uterus of a patient, the catheter having a first lumen, a second lumen, and a first balloon at a distal portion. The first lumen communicates with the first balloon and the second lumen has an opening within the uterus for injection of x-ray dye or other fluid into the uterus for imaging the uterine cavity and the fallopian tubes of a patient. The first balloon contains a gas to form along with the first lumen a chamber to monitor pressure within the uterus to thereby determine if excessive pressure is being applied to the fallopian tubes of the patient. A sensor is in communication with the first lumen to measure pressure about a circumferential area of the balloon to measure pressure in the uterus to provide readings of intrauterine pressure. 113-. (canceled)14. A multi-lumen catheter for monitoring intrauterine pressure to prevent damage to the fallopian tubes of a patient while determining patency , the catheter comprising an elongated body configured and dimensioned for insertion into a uterus of a patient , the catheter having a first lumen , a second lumen and a pressure sensor , the second lumen having an opening within in communication with the uterus for injection of dye or other fluid out of the opening and into the uterus to assess a condition of the fallopian tubes , the pressure sensor monitoring pressure within the uterus to thereby assess if pressure beyond a predetermined pressure is being applied to the fallopian tubes of the patient in response to the injection and condition of the fallopian tubes.15. The catheter of claim 14 , wherein the catheter further comprises a pressure balloon for monitoring pressure claim 14 , a third lumen and a blocking balloon claim 14 , the third lumen communicating with the blocking balloon to inflate the blocking balloon to block outflow of dye and retain the catheter claim 14 , ...

SELF-INFLATING ANORECTAL EXPULSION DEVICE

An anorectal expulsion device includes a balloon having a wall that extends between proximal and distal ends of the balloon and defines a balloon interior. The balloon interior contains a self-expanding, low compression-set material (e.g., open cell foam). The device also includes a catheter that extends through the proximal end of the balloon and at least a portion of the balloon interior. An interior of the catheter is in fluid communication with the balloon interior. The device also includes a termination component (e.g., a cap or a valve) coupled to the catheter at a position along the catheter that is outside of and proximal to the proximal end of the balloon (e.g., at the proximal end of the catheter). The physical configuration of the termination component is adjustable, and controls whether the balloon interior is in fluid communication with the external environment. 1. A diagnostic device comprising:a balloon having (i) a proximal balloon end, (ii) a distal balloon end, and (iii) a balloon wall that extends between the proximal balloon end and the distal balloon end, wherein the balloon wall defines a balloon interior that contains a self-expanding, low compression-set material;a catheter having a proximal catheter end and a distal catheter end, wherein the catheter extends through an opening in the proximal balloon end, and wherein a lumen of the catheter is in fluid communication with the balloon interior; anda termination component coupled to the catheter at a position along the catheter that is proximal to the proximal balloon end, wherein (i) when the termination component is in a first physical configuration, the balloon interior is not in fluid communication with an environment external to the catheter at the proximal catheter end, and (ii) when the termination component is in a second physical configuration different than the first physical configuration, the balloon interior is in fluid communication with the environment external to the catheter at ...

SYSTEMS AND METHODS FOR LOCATING AND/OR CHARACTERIZING INTRAGASTRIC DEVICES

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of tracking and locating the same are provided. 1. A system for electromagnetically locating an intragastric device in three dimensional space , in real time , the system comprising:a) an electromagnetic field generator configured to generate an electromagnetic field;b) a removably attachable inductive reference sensor adapted to be removably attached to a body positioned within the electromagnetic field, whereby a reference sensor signal is generated and the reference sensor signal carries reference sensor position information associated with a position of the reference sensor within the electromagnetic field at an instance in time;c) a swallowable target sensor adapted to be positioned within the electromagnetic field, whereby a target sensor signal is generated and the target sensor signal carries target sensor position information associated with a position of the target sensor within the electromagnetic field at the instance in time; i) the processor processes the reference sensor signal so as to create one or more reference indicia associated with the position of the reference sensor at the instance in time; and', 'ii) the processor processes the target sensor signal so as to create one or more target indicia associated with the position of the target sensor at the instance in time; and, 'd) a processor adapted to be in electronic communication with the reference sensor and the target sensor, so as to receive the reference sensor signal and the target sensor signal; wherein'}e) a display adapted to be in electronic communication with the processor and configured to display the one or more reference indicia and the one or more target indicia.2. The system of claim 1 , wherein the instance in time comprises a plurality of instances in time.3. The system of claim 2 , whereina) the processor iteratively processes the received reference sensor signal ...

SYSTEM AND APPARATUS COMPRISING A MULTI-SENSOR CATHETER FOR RIGHT HEART AND PULMONARY ARTERY CATHETERIZATION

A system comprising a multi-sensor catheter for monitoring of a cardiac hemodynamic condition, e.g. heart failure, is disclosed. The multi-sensor catheter comprises multi-lumen catheter tubing comprising first and second optical pressure sensors, and their respective optical fibers and connectors. For right heart and pulmonary artery catheterization, a flow-directed multi-sensor catheter comprises a guidewire lumen, an inflatable balloon tip, and sensor locations are configured for placement of a sensor in each of the right atrium and pulmonary artery, for measurement of central venous pressure in the right atrium and a pulmonary artery pressure. An optical fiber for oximetry may be included. The outside diameter is small enough for insertion through a vein of the arm. For monitoring of a left atrial shunt, sensors of a multi-sensor catheter are configured for measuring pressures upstream and downstream of the shunt, e.g. in the left and right atria, or left atrium and coronary sinus. 1. A flow-directed multi-sensor catheter for right heart and pulmonary artery catheterization configured for assessment of a cardiac hemodynamic condition , through direct monitoring of a right atrial pressure and a pulmonary artery pressure , comprising:a length of multi-lumen catheter tubing comprising a plurality of lumens extending between a proximal end and a distal end comprising an atraumatic distal tip;one of the lumens being a guidewire lumen having a proximal port and an opening at the distal tip of the catheter tubing,an inflatable balloon near the distal tip, and one of the lumens being a balloon inflation lumen, the inflatable balloon being coupled by the balloon inflation lumen to a balloon inflation port at the proximal end of the catheter tubing;a plurality of optical sensors and a plurality of optical fibers;a sensor end of each optical fiber being attached and optically coupled to an individual one of the plurality of optical sensors;each optical sensor and its ...

OXYGEN MEASUREMENT DEVICE AND OXYGEN MEASUREMENT SYSTEM

An oxygen measurement device constituting an oxygen measurement system includes a urethral catheter and an oxygen sensor main body. The urethral catheter has a shaft in which a urethral catheter lumen that enables circulation of urine flowed in via a urethral catheter port from inside a bladder is formed; and has a hub in which a urine lumen that is provided at a proximal end of the shaft and communicates with the urethral catheter lumen is formed. The oxygen sensor main body is provided on the hub in a manner capable of being brought into contact with urine circulating in the urine lumen, and detects oxygen in the urine. 1. An oxygen measurement device that measures oxygen in a patient's urine , the oxygen measurement device comprising:an elongated urethral catheter possessing a distal portion that is positionable in a bladder of the patient, the elongated urethral catheter being comprised of a wall surrounding a urethral catheter lumen that extends from a distal end of the elongated urethral catheter to a proximal end of the elongated urethral catheter, the elongated urethral catheter including a urethral catheter port that passes through the wall of the elongated urethral catheter and communicates with the urethral catheter lumen to permit urine in the patient's bladder to enter the urethral catheter lumen by way of the urethral catheter port when the distal portion of the elongated urethral catheter is positioned in the patient's bladder;a hub provided at the proximal end of the elongated urethral catheter, the hub being comprised of a wall that surrounds a lumen extending throughout the hub and communicating with the urethral catheter lumen so that the urine flowing in the urethral catheter lumen circulates into the lumen in the hub; anda sensor that detects oxygen in the urine flowing in the lumen of the hub, the sensor comprising phosphor supported on a base, the base being mounted in the wall of the hub and the phosphor being exposed to the lumen in the hub ...

Monitoring system and oxygen measurement system

A monitoring system which constitutes an oxygen measurement system includes: an oxygen partial pressure calculation unit that calculates an oxygen partial pressure in urine based on an output signal from the oxygen measurement device; a monitor that displays the oxygen partial pressure calculated by the oxygen partial pressure calculation unit; and a display control unit that changes a format of display of the oxygen partial pressure displayed by the monitor according to the flow rate of urine acquired based on the output signal from the oxygen measurement device.

SYSTEM AND APPARATUS COMPRISING A MULTI-SENSOR CATHETER FOR RIGHT HEART AND PULMONARY ARTERY CATHETERIZATION

A system and apparatus comprising a multi-sensor catheter for right heart and pulmonary artery catheterization is disclosed. The multi-sensor catheter comprises multi-lumen catheter tubing into which at least three optical pressure sensors, and their respective optical fibers, are inserted. The three optical pressure sensors are arranged within a distal end portion of the catheter, spaced apart lengthwise within the distal end portion for measuring pressure concurrently at each sensor location. The sensor locations are configured for placement of at least one sensor in each of the right atrium, the right ventricle and the pulmonary artery, for concurrent measurement of pressure at each sensor location. The sensor arrangement may further comprise an optical thermo-dilution sensor, and another lumen is provided for fluid injection for thermo-dilution measurements. The catheter may comprise an inflatable balloon tip and a guidewire lumen, and preferably has an outside diameter of 6 French or less. 1. A multi-sensor catheter for right heart and pulmonary artery catheterization , comprising:a length of multi-lumen catheter tubing extending between a proximal end and a distal end, having an outside diameter of ≦8 French, and the distal end comprising an atraumatic tip;a plurality of optical sensors and a plurality of optical fibers; a sensor end of each optical fiber being attached and optically coupled to an individual one of the plurality of optical sensors;each optical sensor and its optical fiber being inserted into a respective lumen of the multi-lumen catheter tubing, the sensors being spaced apart lengthwise to provide a sensor arrangement with said plurality of optical sensors positioned at respective sensor locations spaced apart lengthwise within a distal end portion of the catheter tubing;a proximal end of each of the plurality of optical fibers being coupled to an optical input/output connector at the proximal end of the guidewire for connection to an optical ...

IMPEDANCE DEVICES AND METHODS OF USING THE SAME TO OBTAIN LUMINAL ORGAN MEASUREMENTS

Impedance devices and methods of using the same to obtain luminal organ measurements. In at least one embodiment of an impedance device of the present disclosure, the impedance device comprises an elongated body having a distal body end, and a first electrode located along the elongated body at or near the distal body end, the first electrode configured to obtain one or more conductance values within a mammalian luminal organ within an electric field, wherein a measured parameter of the mammalian luminal organ can be calculated based in part upon the one or more conductance values obtained by the first electrode. 1. An impedance device , comprising:an elongated body having a distal body end; anda first electrode located along the elongated body at the distal body end, the first electrode configured to obtain one or more conductance values within a mammalian luminal organ within an electric field;wherein the first electrode is configured to operate as an excitation electrode and a detection electrode; andwherein a measured parameter of the mammalian luminal organ can be calculated based in part upon the one or more conductance values obtained by the first electrode.2. The impedance device of claim 1 , wherein the first electrode is configured to generate the electric field with an external electrode within a mammalian body when the external electrode that is not coupled to the elongated body is positioned upon or within the mammalian body and when the first electrode and the external electrode are activated.3. The impedance device of claim 1 , wherein the first electrode is configured to detect the electric field generated by the first electrode and the external electrode.4. The impedance device of claim 1 , wherein the elongated body is selected from the group consisting of an elongated wire and an elongated catheter.5. The impedance device of claim 1 , further comprising:a data acquisition and processing system in communication with the impedance device and ...

Large surface area temperature sensing device

A temperature probe for monitoring temperatures of a surface of a tissue or organ within the body of a subject includes a section with a substantially two-dimensional arrangement and a plurality of temperature sensors positioned across an area defined by the substantially two-dimensional arrangement. Such an apparatus may be used in conjunction with procedures in which thermal techniques are used to diagnose a disease state or treat diseased tissue. Specifically, a temperature probe may be used to monitor temperatures across an area of a surface of a tissue or organ located close to the treated tissue to prevent subjection of the monitored tissue or organ to potentially damaging temperatures.

Catheter assembly

A catheter hub assembly includes a body. A pressure sensor is disposed within the body to sense pressure within a catheter and communicating with the body The body has a chamber formed therein having a predetermined volume. A stopper assembly, slideably moves to engage the body forming a gastight seal within the chamber for pushing a column of gas ahead of the stopper assembly as the stopper assembly moves from a first position to a second position.

Electronic catheter stethoscope

An electronic catheter stethoscope measures and analyzes acoustic fields and dynamic pressure variations in the gaseous or liquid fluid inside a conventional medical catheter that is positioned in a patient's urologic, digestive, reproductive, cardiovascular, neurological or pulmonary system. Measurement transducers are installed in a housing connectable to multiple preselected medical catheters. The transducers detect bodily functions that are transmitted to the preselected catheter from within the body. The transducers, housing, electrical interface and signal processing electronics are positioned outside the body.

DEVICES, SYSTEMS AND METHODS FOR USING AND MONITORING MEDICAL DEVICES

Medical devices are provided, comprising a medical device and a sensor. 1. A screw comprising a sensor module , the sensor module comprising: a sensor channel; and a communication interface coupled to the sensor channel , where the screw is configured as a bone screw.2. The screw of wherein the sensor channel includes a sensor and a sensor channel coupled to the sensor and to the communication interface.3. The screw of wherein the sensor is a microelectromechanical sensor (MEMS) selected from one or more of the following sensors: a global-positioning-system (GPS) claim 2 , accelerometer claim 2 , Hall-effect claim 2 , electrical claim 2 , magnetic claim 2 , thermal claim 2 , pressure claim 2 , radiation claim 2 , optical claim 2 , quantity-differential claim 2 , capacitive claim 2 , inductive claim 2 , and time.4. (canceled)5. The screw of wherein said sensor includes one or more of the following sensors: fluid pressure sensors claim 2 , fluid volume sensors claim 2 , contact sensors claim 2 , position sensors claim 2 , pulse pressure sensors claim 2 , blood volume sensors claim 2 , blood flow sensors claim 2 , chemistry sensors claim 2 , metabolic sensors claim 2 , accelerometers claim 2 , mechanical stress sensors and temperature sensors.6. (canceled)7. (canceled)8. The screw of claim 1 , further comprising a power supply coupled to the sensor channel and the communication interface.9. (canceled)10. (canceled)11. The screw of claim 1 , further comprising a controller coupled to the sensor channel and the communication interface.1223-. (canceled)24. A method claim 1 , comprising: sensing a physical quantity using the screw of ; and generating a representation of the sensed quantity.25. (canceled)26. (canceled)27. The method of claim 24 , further comprising storing the representation of the sensed quantity.28. The method of claim 24 , further comprising transmitting wirelessly the representation of the sensed quantity to a device.29. The method of claim 24 , further ...

Applying Bipolar Ablation Energy Between Shorted Electrode Groups

A system includes a catheter, a switching assembly, and a processor. The catheter including an expandable frame, which is coupled to a distal end of the catheter, and multiple electrodes, which are disposed on the expandable frame in a radial geometry. The switching assembly is electrically connected to the catheter, and is configured to electrically short between selected ones of the electrodes. The processor is configured, for first and second disjoint groups of the electrodes, to control the switching assembly to electrically short the electrodes within each of the first and second groups, for applying one or more bipolar ablation energy between the first and second groups when the electrodes are placed in contact with a target tissue of the organ.

Sensor carrier

The invention relates to an auxiliary instrument for insertion into vessels or lumens with small inner diameters. The auxiliary instrument has a proximal end and a distal end and has at least one localization element whose position and orientation can be determined with an electromagnetic position detection system. The localization element is located directly adjacent to or at least close to the distal end of the auxiliary instrument and is configured to capture an alternating electromagnetic field. A distal end region of the auxiliary instrument extends from the distal end of the auxiliary instrument to a proximal end of the localization element such that the localization element is located within the distal end region. In that part of the distal end region in which the localization element is located, the auxiliary instrument has a low bending stiffness of less than 10 Nmm 2 , at least in sections. At least two lines are led from the localization element to the proximal end of the auxiliary instrument and are electrically conductively connected at least to the localization element. The localization element has a length with an amount that is at least ten times the amount of an outer diameter of the localization element.

PRESSURE CATHETER CONNECTOR

A connector for connecting a pressure sensing catheter to charger is provided. The connector can include a first engagement portion engageable with a charger engagement portion of the charger to displace a pressure transmission medium in the charger engagement portion to charge one or more balloons of the pressure sensing catheter. The connector can have a handle that includes a tab terminating in an end surface engageable with an engagement surface of the charger when the first engagement portion engages with the charger engagement portion. The connector includes a distal abutment portion that engages with a portion of the charger engagement portion to provide an audible or tactile feedback, so as to prevent inadvertent overcharging of the balloons. 1. A connector for a pressure sensing catheter , the pressure sensing catheter comprising a catheter lumen and one or more balloons , at least one of the balloons being fluidly coupled to the catheter lumen , the one or more balloons being charged by a pressure transmission medium displaced when the pressure sensing catheter is connected to a charger via the connector , the connector comprising:a body having a lumen fluidly connectable to the catheter lumen of the pressure sensing catheter for transmitting the displaced pressure transmission medium;a first engagement portion attached to the body, the first engagement portion being engageable with a charger engagement portion of the charger, wherein engagement of the first engagement portion with the charger engagement portion displaces the pressure transmission medium present in the charger engagement portion to charge the one or more balloons;a handle attached to the body at a handle attachment portion, the handle terminating in a first end and a second end opposite to the first end,the handle being elongate and disposed in a direction parallel to a longitudinal axis of the connector, such that the first end and the second end are positioned apart in the direction ...

Smart device for bladder mapping

Systems, devices and methods for the treatment of bladder conditions using bladder visualization without the need for optical elements and for subsequent direct electrical pacing are provided. The systems, devices and methods generally apply pacing stimulus directly to the bladder wall, from one or more of the inner and outer bladder surfaces.

Apparatus and method for endovascular device guiding and positioning using physiological parameters

An endovascular navigation system and method are disclosed. The endovascular navigation system includes an elongate flexible member configured to access the venous vasculature of a patient, a processor, and a display. The elongate flexible member includes an endovascular electrogram lead disposed at a distal end of the elongate flexible member and configured to sense an endovascular electrogram signal of the venous vasculature of the patient, and a first wireless interface configured to wirelessly transmit the endovascular electrogram signal to the processor. The processor includes a second wireless interface configured to wirelessly receive the endovascular electrogram signal from the elongate flexible member. The processor is configured to determine that the position of the distal end of the elongate flexible member is within a predetermined structure within the venous vasculature of the patient. The display is configured to display a visual indication that the distal end of the elongate flexible member is within the predetermined structure within the venous vasculature of the patient.

EXPANDABLE BALLOON MAPPING AND ABLATION DEVICE

The present disclosure relates to the field of tissue mapping and ablation. Specifically, the present disclosure relates to expandable medical devices for identifying and treating local anatomical abnormalities within a body lumen. More specifically, the present disclosure relates to systems and methods of focal treatment for overactive bladders. 1. A medical device , comprising:a balloon configured to move between a collapsed configuration and an expanded configuration;a plurality of electrodes carried about an outer surface of the balloon; anda spacer disposed between the surface of the balloon and each of the plurality of electrodes.2. The medical device of claim 1 , wherein the balloon is a non-compliant balloon.3. The medical device of claim 1 , wherein the balloon comprises a polymer selected from the group consisting of PEBAX claim 1 , PET claim 1 , PEN claim 1 , PBT claim 1 , PEEK claim 1 , Hytrel claim 1 , polyurethane and nylon.4. The medical device of claim 1 , wherein each of the plurality of electrodes extends outward from the outer surface of the balloon.5. The medical device of claim 1 , wherein each of the plurality of electrodes is electrically coupled to an ablation energy source.6. The medical device of claim 1 , wherein each of the plurality of electrodes is electrically coupled to an electrical activity processing system.7. The medical device of claim 1 , wherein the electrodes are configured to act as one or more of the following: sensing electrodes claim 1 , mapping electrodes claim 1 , stimulating electrodes claim 1 , ablation electrodes.8. A medical device claim 1 , comprising:a balloon configured to move between a collapsed configuration and an expanded configuration;an expandable-collapsible framework disposed about an outer surface of the balloon; anda plurality of electrodes carried about an outer surface of the framework.9. The medical device of claim 8 , wherein the framework is free-floating about the surface of the balloon.10. The ...

Methods and systems for determining vascular bodily lumen information and guiding medical devices

Methods and systems for determining information about a vascular bodily lumen are described. An exemplary method includes generating an electrical signal, delivering the electrical signal to a plurality of excitation elements in the vicinity of the vascular bodily lumen, measuring a responsive electrical signal from a plurality of sensing elements in response to the delivered electrical signal, and determining a lumen dimension. Specific embodiments include generating a multiple frequency electrical signal. Another embodiment includes measuring a plurality of responsive signals at a plurality of frequencies. Still other embodiments include using spatial diversity of the excitation elements. Yet other embodiments use method for calibration and de-embedding of such measurements to determine the lumen dimensions. Diagnostic devices incorporating the method are also disclosed, including guide wires, catheters and implants. The methods and systems described herein are advantageous as they do not include injecting a second fluid for the measurements.

CRYOGENIC TREATMENT SYSTEMS

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session. 1. A system for inflating and evacuating a liner , comprising:an expandable liner configured for positioning within a body lumen;a pump in fluid communication with the liner;a pump output pathway fluidly coupling the pump and the liner;a pump input pathway fluidly coupling the pump and the liner;a first valve positioned along the pump output pathway and configurable between an open position and a closed position;a second valve positioned along the pump input pathway and configurable between an open position and a closed position;wherein the liner is expandable via the pump with air received through the second valve when the second valve is in the closed position and the first valve is in the open position, andwherein the liner is evacuated via the pump when the second valve is in the open position and the first valve is in the closed position such that a fluid within the liner is exhausted via the first valve.2. The system of further comprising a cryogenic fluid reservoir fluidly coupled to the liner.3. The system of wherein the liner comprises a non-distensible membrane.4. The system of wherein the pump comprises a non-reversible pump.5. The system of wherein the first valve comprises a 3-way valve.6. The system of wherein the 3-way valve comprises a 3-way ...

IMPEDANCE DEVICES AND METHODS OF USING THE SAME TO OBTAIN LUMINAL ORGAN MEASUREMENTS

Impedance systems and methods of use. The impedance systems include only one electrode positioned upon an elongate body, and at least two external electrodes. The only one electrode is configured to both excite an electric field and detect the electric field. The only one electrode works with a first external electrode to generate an electric field and works with a second external electrode to obtain conductance measurements from the electric field. In other embodiments the first external electrode and/or the second external electrode may also be configured to both excite an electric field and detect the electric field. In other embodiments, both the first external electrode and the second external electrode can work with the only one electrode to both generate an electric field and obtain at least one conductance measurement. 1. An impedance system , comprising:an elongated body;only one electrode located on the elongated body,at least two external electrodes external to the elongated body;wherein the only one electrode is configured to operate as both an excitation electrode to generate an electric field and as a detection electrode to obtain one or more conductance values within a luminal organ within the electric field.2. The impedance system of claim 1 , wherein the at least two external electrodes comprise a first external electrode and a second external electrode claim 1 , wherein the only one electrode is configured to generate the electric field with the first external electrode and further configured to obtain the one or more conductance values with the second external electrode.3. The impedance system of claim 1 , wherein the at least two external electrodes comprise a first external electrode and a second external electrode claim 1 , wherein the first external electrode is configured to both generate the electric field with the only one electrode and obtain the one or more conductance values with the only one electrode.4. The impedance system of claim 3 ...

TISSUE ABLATION AND MONITORING THEREOF

An ablation catheter including an elongate shaft, an inflatable balloon positioned at a distal region of the elongate shaft, a first ablation electrode disposed outside of and carried by an outer surface of the inflatable balloon, a first ultrasound transducer disposed outside of the inflatable balloon, and a flexible circuit. The flexible circuit includes a first conductor and a second conductor and is disposed outside of and carried by the outer surface of the inflatable balloon. The first conductor is in electrical communication with the first ablation electrode, and the second conductor in electrical communication with the first ultrasound transducer. 1. An ablation catheter , comprising:an elongate shaft;an inflatable balloon positioned at a distal region of the elongate shaft;a first ablation electrode disposed outside of and carried by an outer surface of the inflatable balloon;a first ultrasound transducer disposed outside of the inflatable balloon; anda flexible circuit, including a first conductor and a second conductor, disposed outside of and carried by the outer surface of the inflatable balloon, the first conductor in electrical communication with the first ablation electrode, and the second conductor in electrical communication with the first ultrasound transducer.2. The ablation catheter of claim 1 , wherein the first ultrasound transducer is positioned within a periphery of the first ablation electrode.3. The ablation catheter of claim 1 , wherein the first ultrasound transducer is disposed under the first ablation electrode.4. The ablation catheter of claim 1 , wherein the first ultrasound transducer is an ultrasound receiver.5. The ablation catheter of claim 1 , wherein the first ultrasound transducer is an ultrasound emitter.6. The ablation catheter of claim 1 , wherein the first ultrasound transducer is at least partially surrounded by an insulation layer.6. The ablation catheter of claim 1 , further comprising:a second ultrasound transducer ...

DEPLOYABLE LOCAL MAGNETIC RESONANCE IMAGING COIL AND METHODS FOR USE THEREOF

A catheter device for deploying a local magnetic resonance imaging coil is provided. The catheter device comprises an inner shaft, an outer sheath, and a local magnetic resonance imaging coil. The outer sheath includes a plurality of slits extending in an axial direction proximate a distal end of the outer sheath. The slits separate a portion of the outer sheath into a plurality of struts. The local magnetic resonance imaging coil is disposed between the inner shaft and the outer sheath and is coupled to the plurality of struts. Moving the outer sheath relative to the inner shaft expands the catheter device from a contracted position to an expanded position. 1. A catheter device for deploying a local magnetic resonance imaging coil , the catheter device comprising:an inner shaft;an outer sheath enveloping the inner shaft and including a plurality of slits extending in an axial direction proximate a distal end of the outer sheath, the slits separating a portion of the outer sheath into a plurality of struts;a local magnetic resonance imaging coil disposed between the inner shaft and the outer sheath and coupled to the plurality of struts;wherein moving the outer sheath relative to the inner shaft expands the catheter device from a contracted device position to an expanded device position; andwherein when the catheter device is in the expanded position, the struts are bent radially outwards away from the inner shaft expanding the local magnetic resonance imaging coil from a contracted coil position to an expanded coil position.2. The catheter device of further comprising a handle including a sliding member rigidly fixed to the outer sheath.3. The catheter device of in which the sliding member is configured to move the outer sheath relative to the inner shaft to expand the catheter device from the contracted device position to the expanded device position.4. The catheter device of in which the inner shaft and the outer sheath are rigidly fixed relative to each other at ...

BALLOON POSITIONING USING MAGNETIC RESONANCE IMAGING (MRI) BLOOD FLOW MEASUREMENTS

A method for positioning a balloon, which is fitted at a distal end of a catheter, at an ostium of a blood vessel of a patient, includes attempting to achieve circumferential physical contact between the balloon and an entire circumference of the ostium. One or more slices across the ostium are imaged with magnetic resonance imaging (MRI), and the extent of blood flow along the circumference of the ostium is estimated using the MRI. Based on the estimated extent of blood flow, an extent of the circumferential physical contact between the balloon and the ostium is indicated to a user. 1. A method , comprising:positioning a balloon, which is fitted at a distal end of a catheter, at an ostium of a blood vessel of a patient, attempting to achieve circumferential physical contact between the balloon and an entire circumference of the ostium;imaging with magnetic resonance imaging (MRI) one or more slices across the ostium, and estimating using the MRI the extent of blood flow along the circumference of the ostium; andbased on the estimated extent of blood flow, indicating to a user an extent of the circumferential physical contact between the balloon and the ostium.2. The method according to claim 1 , wherein positioning the balloon comprises positioning the balloon at an ostium of a pulmonary vein.3. The method according to claim 1 , and comprising claim 1 , based on the indicated extent of the circumferential physical contact claim 1 , performing a treatment using the balloon.4. The method according to claim 3 , wherein performing the treatment using the balloon comprises performing radiofrequency (RF) ablation.5. The method according to claim 3 , wherein performing the treatment using the balloon comprises performing cryogenic ablation.6. The method according to claim 3 , wherein performing the treatment using the balloon comprises performing laser ablation.7. The method according to claim 1 , wherein imaging the slices comprises applying an MRI protocol that does not ...

DYNAMIC ABLATION AND SENSING ACCORDING TO CONTACT OF SEGMENTED ELECTRODES

A system includes an expandable distal end of a catheter and a processor. The expandable distal end has multiple electrodes that are configured to be placed in contact with a tissue in an organ and to apply ablative power to tissue. The processor is configured to, during application of the ablative power, determine whether a physical contact between the electrodes and tissue meets a predefined contact quality, and, if the physical contact of an electrode among the electrodes with the tissue does not meet the predefined contact quality, re-use the electrode for electrophysiological (EP) sensing. 1. A system , comprising:an expandable distal end of a catheter having multiple electrodes that are configured to be placed in contact with tissue in an organ and to apply ablative power to tissue; and during application of the ablative power, determine whether a physical contact between the electrodes and tissue meets a predefined contact quality; and', 'if the physical contact of an electrode among the electrodes with the tissue does not meet the predefined contact quality, re-use the electrode for electrophysiological (EP) sensing., 'a processor, which is configured to2. The system according to claim 1 , wherein the ablative power comprises at least one of a radiofrequency (RF) power outputted by an RF generator and irreversible electroporation (IRE) pulses outputted by an IRE pulse generator.3. The system according to claim 1 , and comprising a switching assembly configured to switch the electrode between a generator of the ablative power and an EP sensing system claim 1 , wherein the processor is configured to control the switching assembly to (i) initially connect the electrode to the generator and (ii) subsequently connect the electrode to the EP sensing system for re-using the electrode for EP sensing.4. The system according to claim 3 , wherein each of the electrodes comprises a plurality of electrode segments claim 3 , and wherein the switching assembly and the ...

PRECISION CHEMICAL ABLATION AND TREATMENT OF TISSUES

A method includes delivering a composition to a tissue site within a volume of tissue; and at least one of monitoring the effect of the composition on an electrophysiological state of a region in the volume of tissue and monitoring the migration of the composition in the region after delivery to the site; wherein the composition comprises an ablative agent for performing a treatment within a body of a subject and an excipient for limiting migration of at least one of the composition and the ablative agent within the body after delivery to the tissue site. 1. A method , comprising:delivering a composition to a tissue site within a volume of tissue; andat least one of monitoring the effect of the composition on an electrophysiological state of a region in the volume of tissue and monitoring the migration of the composition in the region after delivery to the site;wherein the composition comprises an ablative agent for performing a treatment within a body of a subject and an excipient for limiting migration of at least one of the composition and the ablative agent within the body after delivery to the tissue site.2. The method in accordance with claim 1 , wherein delivering the composition to the tissue site comprises forming a pattern of the composition in the region.3. The method in accordance with claim 2 , wherein the pattern is formed in the shape of a ring around the perimeter of the region claim 2 , so as to isolate the region from the surrounding volume of tissue.4. The method in accordance with claim 2 , wherein the pattern is formed through deposition of a plurality of boluses at points over a three-dimensional path within the volume of tissue.5. The method in accordance with claim 2 , wherein the region includes a tumor and the pattern is formed over the margin of the tumor.6. The method in accordance with claim 1 , wherein delivering the composition to the tissue site comprises:identifying a branch of an arterial tree that exclusively provides blood flow to ...

Cyrogenic treatment systems

Methods and apparatus for the treatment of a body cavity or lumen are described where a heated fluid and/or gas may be introduced through a catheter and into treatment area within the body contained between one or more inflatable/expandable members. The catheter may also have optional pressure and temperature sensing elements which may allow for control of the pressure and temperature within the treatment zone and also prevent the pressure from exceeding a pressure of the inflatable/expandable members to thereby contain the treatment area between these inflatable/expandable members. Optionally, a chilled, room temperature, or warmed fluid such as water may then be used to rapidly terminate the treatment session.

Probe Deployment Device

The present disclosure relates to an apparatus for mounting on a guide member for insertion into an anatomical cavity, the apparatus comprising a body defining a cavity for receiving a guide member therethrough, a drive arrangement for moving the body along a guide member disposed through the body, a probe secured to the body for, in use, obtaining a measurement from, taking a sample of, applying a substance to, or applying a therapy to, an environment of the body, and a measurement arrangement for measuring a position relative to the guide member disposed through the body. 1. An apparatus for mounting on a guide member for insertion into an anatomical cavity , the apparatus comprising:a body defining a cavity for receiving a guide member therethrough;a drive arrangement for moving the body along a guide member disposed through the body;a probe secured to the body for, in use, obtaining a measurement from, taking a sample of, applying a substance to, or applying a therapy to, an environment of the body; anda measurement arrangement for measuring a position relative to the guide member disposed through the body.2. (canceled)3. The apparatus of claim 14 , wherein the drive arrangement comprises one or more rotating members coupled to the body and arranged to engage the guide member to move the body along the guide member.4. The apparatus of claim 3 , wherein the one or more rotating members are arranged to move the body along the guide member by frictional engagement of the guide member.5. The apparatus of claim 3 , wherein the one or more rotating members are configured as a pinion or a worm gear claim 3 , the pinion or the worm gear being arranged to move the body along the guide member by engaging a rack surface on the guide member.6. The apparatus of any one of claim 3 , wherein the drive arrangement comprises a capstan and a tendon engaging the capstan for actuating the drive arrangement.7. The apparatus of any one of claim 3 , wherein the drive arrangement ...

Monitoring of Neuromodulation Using Biomarkers

Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers. 129-. (canceled)30. A method of assessing efficacy of a renal neuromodulation procedure in a human subject , the method comprising:determining a baseline level of one or more biomarkers in bodily fluid collected from the human subject;at least partially inhibiting sympathetic neural activity in a renal nerve of the human subject via energy delivered by a neuromodulation assembly positioned within a renal blood vessel of the human subject;determining a post-neuromodulation level for the biomarker(s) in bodily fluid collected from the human subject within about 5 minutes to about 14 days post-neuromodulation; andcomparing the post-neuromodulation level to the baseline level,wherein the neuromodulation procedure is classified as at least partially successful if the post-neuromodulation level differs significantly from the baseline level.31. The method of wherein the one or more biomarkers includes a catecholamine metabolite.32. The method of wherein the one or more biomarkers includes norepinephrine and a metabolite thereof in urine collected from the human subject.33. The method of wherein the urine for determining the post-neuromodulation level is collected from the human subject within about 5 minutes to about 30 minutes post-neuromodulation.34. The method of wherein the bodily fluid for determining the post-neuromodulation level is collected from the human subject prior to removing the neuromodulation assembly from the human subject.35. The method of wherein the one or more biomarkers includes neuropeptide Y in plasma collected from the human subject.36. The method of wherein the one or more biomarkers includes vasopressin in plasma collected from the human subject.37. The method of wherein the one or more biomarkers includes total catecholamines and metabolites thereof in urine collected ...

SYSTEMS AND METHODS FOR MAKING AND USING MEDICAL ABLATION SYSTEMS HAVING MAPPING CATHETERS WITH IMPROVED ANCHORING ABILITY

A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion. 1. An ablation system comprising:an ablation catheter having a distal portion and a proximal portion, the ablation catheter configured and arranged for insertion into patient vasculature;an expansion element coupled to the distal portion of the ablation catheter, the expansion element configured and arranged for ablating patient tissue;a mapping catheter comprising an elongated body insertable through the catheter and the expansion element, the elongated body comprising a distal end that is extendable from a distal end of the expansion element, the distal end of the elongated body comprising a plurality of electrodes, wherein the distal end is formed, at least in part, from a shape memory material that bends into a preformed shape upon release from a confined space, the preformed shape comprising a loop transverse to a longitudinal axis of the elongated body; anda control module coupled to the ablation catheter and the mapping catheter, the control module configured and arranged for controlling mapping of electrical activity by the mapping catheter and ablation ...

A TEMPERATURE SENSING LAVAGE CATHETER

A catheter for measuring temperature of a fluid in a body cavity includes a catheter body having a proximal end and an opposite distal end with a tip; an inflow lumen; an outflow lumen; and a temperature sensor lumen having a temperature sensor. The temperature sensor lumen is arranged closer to the outflow lumen and to the inflow lumen in the catheter body. The temperature sensor includes a sensing element positioned at the tip of the distal end to measure a temperature of a fluid in a body cavity when the distal end of the catheter body is inserted into a body cavity.

Bladder urodynamic measurement apparatus

A bladder urodynamic measurement apparatus is provided, which can measure and record pressure inside a bladder continuously for a short time period to a long time period. A bladder urodynamic measurement apparatus 10 according to the present invention includes a pressure sensor 20 configured to measure a value of pressure that is applied to an inside of a urinary catheter 50 by urine in a bladder 55, and a recording device 30 configured to record a pressure value measured by the pressure sensor 20.

SYSTEMS, METHODS AND DEVICES FOR DIAGNOSING SLEEP APNEA

Systems, methods and devices for diagnosing sleep apnea are provided herein. In one example, a device for detecting airway obstructions may be provided where the device may include a wearable hollow nasal tube to be positioned in an upper airway above a constriction point and an end imaging sensor coupled to the nasal tube to collect airway image data. The device further may include a controller and communication interface to communicatively link and relay airway image data to a select remote device to determine airway obstructions. In some examples, a method may be provided including receiving airway image data from a remote end imaging sensor coupled to a nasal tube disposed within an upper airway above a constriction point, and analyzing the airway image data and displaying in a sleep study report the airway image data to identify airway closures related to obstructive sleep apnea. 1. A device for detecting airway obstructions during sleep to diagnose OSA , comprising:a wearable hollow nasal tube to be positioned in an upper airway above a constriction point;an end imaging sensor coupled to the nasal tube to collect airway image data; anda controller and communication interface to communicatively link and relay the airway image data during sleep to a select remote device to determine airway obstructions.2. The device of claim 1 , further comprising an inflatable balloon to anchor the nasal tube such that the end imaging sensor is disposed in an airway image data collection position.3. The device of claim 1 , wherein the nasal tube is curved relative to a longitudinal axis.4. The device of claim 1 , wherein the end imaging sensor is placed at a distal end of the nasal tube such that an image data collection position of the end imaging sensor is within a nasopharynx above the constriction point claim 1 , and wherein the end imaging sensor is further angled downward relative to a nose opening to view an airway.5. The device of claim 1 , wherein the end imaging ...

Controlled-Flow Infusion Catheter and Method

Devices and methods for determining fluid flow resistance at a targeted location in a bodily fluid vessel by monitoring changes in pressure gradiants across the location while fluid flow is being manipulated by introducing infusate into the target area at different rates. 1. A method of making real-time determinations of flow resistance through a targeted location in a fluid vessel comprising:placing a distal pressure sensor distal of a targeted location in a fluid vessel;placing a proximal pressure sensor proximal of the targeted location in the fluid vessel;increasing resistance to natural blood flow through the vessel at the targeted location;introducing infusate at an infusate flow rate into the vessel proximal of the distal sensor;changing the infusate flow rate while monitoring pressure differences between the proximal and distal sensors;calculating flow resistance using a measured change in pressure differences in response to the change in infusate flow rate.2. The method of wherein placing said distal pressure sensor distal of the targeted location in the fluid vessel comprises placing a pressure-sensing guide wire distal of the targeted location in the fluid vessel.3. The method of wherein placing said distal pressure sensor distal of the targeted location in the fluid vessel comprises placing a catheter to which said distal pressure sensor is attached at a location such that said distal pressure sensor is distal of the targeted location.4. The method of wherein increasing resistance to natural blood flow through the vessel comprises placing a catheter at the targeted location.5. The method of further comprising inflating a balloon on the catheter.6. The method of wherein introducing infusate at an infusate flow rate into the vessel proximal of the distal sensor comprises activating an infusate pump connected to a catheter having an infusate exit port located at the target location proximal of the distal sensor.7. A method of determining flow resistance ...

SYSTEM AND APPARATUS COMPRISING A MULTI-SENSOR CATHETER FOR RIGHT HEART AND PULMONARY ARTERY CATHETERIZATION

A system and apparatus comprising a multi-sensor catheter for right heart and pulmonary artery catheterization is disclosed. The multi-sensor catheter comprises multi-lumen catheter tubing into which at least three optical pressure sensors, and their respective optical fibers, are inserted. The three optical pressure sensors are arranged within a distal end portion of the catheter, spaced apart lengthwise within the distal end portion for measuring pressure concurrently at each sensor location. The sensor locations are configured for placement of at least one sensor in each of the right atrium, the right ventricle and the pulmonary artery, for concurrent measurement of pressure at each sensor location. The sensor arrangement may further comprise an optical thermo-dilution sensor, and another lumen is provided for fluid injection for thermo-dilution measurements. The catheter may comprise an inflatable balloon tip and a guidewire lumen, and preferably has an outside diameter of 6 French or less. 1. A multi-sensor catheter for right heart and pulmonary artery catheterization comprising:a length of catheter tubing extending between a proximal end and a distal end, and the distal end comprising a distal tip;a plurality of optical sensors and a plurality of optical fibers; a sensor end of each optical fiber being attached and optically coupled to an individual one of the plurality of optical sensors;the plurality of optical sensors and optical fibers extending within the catheter tubing, the sensors being spaced apart lengthwise to provide a sensor arrangement with said plurality of optical sensors positioned at respective sensor locations spaced apart lengthwise within a distal end portion of the catheter tubing;a proximal end of each of the plurality of optical fibers being coupled to an optical input/output connector at the proximal end of the multi-sensor catheter for connection to an optical control system; andthe plurality of optical sensors of the sensor ...

CATHETER ASSEMBLY

A catheter hub assembly includes a body. A pressure sensor is disposed within the body to sense pressure within a catheter and communicating with the body The body has a chamber formed therein having a predetermined volume. A stopper assembly, slideably moves to engage the body forming a gastight seal within the chamber for pushing a column of gas ahead of the stopper assembly as the stopper assembly moves from a first position to a second position. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. An electronics assembly for a catheter comprising:a housing;a first circuitry disposed within said housing;a connector disposed on said housing, said connector including a second circuitry communicating with the first circuitry;a first catheter hub assembly having a first hub assembly housing, a pressure sensor disposed within said hub assembly housing to sense a pressure within a catheter communicating with said housing, the housing having a chamber formed therein, the chamber having a predetermined volume, the pressure sensor communicating with said second circuitry; andat least a second catheter hub assembly having a second hub assembly housing, a second pressure sensor disposed within the second hub assembly housing to sense a pressure within a catheter communicating with the second hub assembly housing, the housing having a chamber formed therein, the chamber having a predetermined volume, and the sensor communicating with the second circuitry.11. The electronics assembly of claim 10 , wherein the connector is selectively attached to the housing.12. The electronics assembly of claim 10 , wherein the hub sub assembly and second hub assembly are affixed to the connector.13. The electronics assembly of claim 10 , further comprising a stopper assembly comprising a bore formed therein claim 10 , a seal disposed at least partially within said bore claim 10 , and extending beyond said bore; the bore ...

SYSTEMS AND METHOD OR USES OF ABLATING CARDIAC TISSUE

The subject of this disclosure is devices, systems, and uses thereof to treat a plurality of patients for paroxysmal atrial fibrillation. The solution can include delivering a multi-electrode radiofrequency balloon catheter and a multi-electrode diagnostic catheter to one or more targeted pulmonary veins; ablating tissue of the one or more targeted pulmonary veins using the multi-electrode radiofrequency balloon catheter; diagnosing the one or more targeted pulmonary veins using the multi-electrode diagnostic catheter; and achieving at least one of a predetermined clinical effectiveness and acute effectiveness of the method or use based on use of the multi-electrode radiofrequency balloon catheter and the multi-electrode diagnostic catheter in the isolation of the one or more targeted pulmonary veins. 1. Use of a multi-electrode radiofrequency balloon catheter to treat a plurality of patients for paroxysmal atrial fibrillation , comprising:delivering the multi-electrode radiofrequency balloon catheter having a plurality of electrodes for radiofrequency ablation and a diagnostic catheter to one or more targeted pulmonary veins;ablating tissue of the one or more targeted pulmonary veins with one or more of the plurality of the electrodes of the multi-electrode radiofrequency balloon catheter;diagnosing the one or more targeted pulmonary veins using the diagnostic catheter; andachieving at least one of a predetermined clinical effectiveness and acute effectiveness of the multi-electrode radiofrequency balloon catheter and the diagnostic catheter in the isolation of the one or more targeted pulmonary veins, during and approximately 3 months after the ablating step;wherein acute effectiveness is defined by confirming if there is an entrance block in all targeted pulmonary veins after adenosine and/or isoproterenol challenge, the acute effectiveness being defined by success greater than approximately 80% for the plurality of patients.2. Use of claim 1 , wherein the acute ...

Pressure Catheter Device

An intrauterine pressure-sensing catheter for detecting pressure changes within the uterus of a patient is disclosed having a tube with a primary lumen extending from a proximal end to a distal end of the elongate tube. A monitor lumen is positioned within the elongate tube between the primary lumen and a wall of the elongate tube and extends from a proximal end of the elongate tube to a distal end of the elongate tube. A compliant balloon is disposed about an exterior of the elongate tube adjacent a distal end tip. A sleeve is slidably mounted on an exterior of the elongate tube and disposed over the compliant balloon during insertion of the catheter within the patient. The distal end tip is configured to prevent movement of the sleeve over the tip and is further configured to provide a zone of protection for the compliant balloon. 1. An intrauterine pressure-sensing catheter for detecting pressure within the uterus of a patient , comprising:an elongate tube comprising a primary lumen extending from a proximal end of the elongate tube to a distal end of the elongate tube;a monitor lumen positioned within the elongate tube between the primary lumen and a wall of the elongate tube, said monitor lumen extending from a proximal end of the elongate tube to a distal end of the elongate tube;a compliant balloon defining an interior chamber in fluid communication with the monitor lumen, said compliant balloon being disposed about an exterior of the elongate tube wherein the monitor lumen and the interior chamber of the compliant balloon define a fluid column;a sleeve slidably mounted on an exterior of the elongate tube and disposed over the compliant balloon during insertion of the catheter within the patient;an integral distal end tip formed from the elongate member and located adjacent to the balloon, the tip comprising an outer diameter that is greater than an outer diameter of the sleeve.2. The pressure sensing catheter of claim 1 , wherein the sleeve comprises a ...

Flex circuit/balloon assemblies utilizing textured surfaces for enhanced bonding

Systems, methods and devices for remodeling a tissue of or adjacent to a body passageway may include or utilize a catheter having an expandable balloon with a plurality of flexible circuits. In some instances, laser texturing may be utilized to facilitate enhanced bonding of the flexible circuits to the expandable balloon.

OXYGEN SENSOR CALIBRATION

An example device includes processing circuitry configured to receive, from an oxygen sensor, an ambient air signal indicative of an oxygen partial pressure of ambient air. The processing circuitry is further configured to receive, from an atmospheric pressure sensor, an atmospheric pressure sensor signal indicative of atmospheric pressure. The processing circuitry is configured to determine, based on the atmospheric pressure sensor signal, an oxygen partial pressure of the ambient air, determine, based at least in part on the oxygen partial pressure of the ambient air and the ambient air signal, the one or more calibration parameters, and calibrate, based on the one or more calibration parameters, the oxygen sensor. The calibrated oxygen sensor may be used to, for example, determine the oxygen content of urine of a patient to monitor renal function of the patient. 1. A method comprising:receiving, by processing circuitry and from an oxygen sensor, an ambient air signal indicative of an oxygen partial pressure of ambient air;receiving, by the processing circuitry and from an atmospheric pressure sensor, an atmospheric pressure sensor signal indicative of atmospheric pressure;determining, by the processing circuitry and based on the atmospheric pressure sensor signal, an oxygen partial pressure of the ambient air;determining, by the processing circuitry and based at least in part on the oxygen partial pressure of the ambient air and the ambient air signal, one or more calibration parameters; andcalibrating, by the processing circuitry and based on the one or more calibration parameters, the oxygen sensor.2. The method of claim 1 , wherein calibrating the oxygen sensor comprises:determining, by the processing circuitry, an oxygen partial pressure in a fluid based on a fluid signal from the oxygen sensor; andapplying, by the processing circuitry, a function to the determined oxygen partial pressure, wherein the function is based on the one or more calibration ...

ADJUSTABLE SURGICAL INSTRUMENTS AND METHODS OF USE AND FABRICATION

A system for assessing an intervertebral disc space comprises an elongated catheter with proximal and distal ends and an expandable body carried at the distal end of the elongated catheter. The expandable body includes a distal cap portion. The system further includes a mandrel extending through the elongated catheter and the expandable body and attached to the distal cap portion. The mandrel is movable within the elongated catheter and the expandable body to reposition the distal cap portion relative to the distal end of the elongated catheter while the expandable body is positioned within the intervertebral disc space. 123-. (canceled)24. A medical device for intervertebral disc assessment and treatment comprising:an elongated catheter with proximal and distal ends;an expandable body comprising an underinflated expandable tube connected to and extending between the distal end of the elongated catheter and distal cap portion; anda mandrel extending through the elongated catheter and the expandable body and fixedly attached to the distal cap portion to control movement of the cap portion within uninflated, underinflated, and fully inflated expandable bodies.25. The medical device of wherein the expandable body is rolled or folded.26. The medical device of wherein the mandrel is fixedly attached to the distal cap portion forming a rigid bond.27. The medical device of wherein the mandrel is formed from a tubular member.28. The medical device of wherein the mandrel includes a handle extending proximally of the proximal end of the catheter.29. The medical device of wherein the mandrel includes an elongated wire member.30. The medical device of wherein the mandrel may elongate the expandable body between 0 and 55 mm.31. The medical device of wherein the mandrel is movable within the elongated catheter during expansion of the expandable body from the uninflated state to the inflated state. Degenerated disc disease refers to a syndrome in which a compromised disc causes ...

APPARATUS AND METHOD FOR INTRA-CARDIAC MAPPING AND ABLATION

An intra-cardiac mapping system is based on locating the ports through which blood flows in or out the heart chambers. For many procedures, such as ablation to cure atrial fibrillation, locating the pulmonary veins and the mitral valve accurately allows to perform a Maze procedure. The location of the ports and valves is based on using the convective cooling effect of the blood flow. The mapping can be performed by a catheter-deployed expandable net or a scanning catheter. The same net or catheter can also perform the ablation procedure. 1. (canceled)2. A method executed by a control computer , the method comprising:the control computer causing a display console to display a plurality of tissue-ablation-pattern elements in a distribution, the plurality of tissue-ablation-pattern elements respectively corresponding to a plurality of ablation elements configured to ablate tissue;the control computer receiving user-input indicating user-selection of some, but not all, of the displayed tissue-ablation-pattern elements as a tissue ablation pattern, the user-selected tissue-ablation-pattern elements comprising a first set of tissue-ablation-pattern elements respectively corresponding to a first set of ablation elements of the plurality of ablation elements; andthe control computer causing the display console to display a representation of the tissue ablation pattern at least in response to the user-input in a manner that distinguishes the user-selected tissue-ablation-pattern elements from others of the tissue-ablation-pattern elements that are not user-selected as part of the tissue ablation pattern, the displayed representation of the tissue ablation pattern displaying the first set of tissue-ablation-pattern elements along a first circumferential path around at least a displayed representation of a first tissue port, wherein the first circumferential path includes a portion that extends radially inward.3. The method of claim 2 , wherein the displayed representation of ...

SYSTEMS AND METHODS FOR SENSING LUNG FLUID AND FUNCTIONALITY

An apparatus for monitoring for accumulation of lung fluid comprises a feeding tube having first electrode(s) positioned thereon for electrical contact with tissue of an esophagus of a target patient including a lower esophageal sphincter (LES) and/or tissue in proximity to the LES, second electrode(s) sized and shaped for contacting skin of the target patient, and a non-transitory memory having stored thereon code instructions for applying alternating current(s) to pair(s) of first and second electrodes, measuring a voltage over the pair(s), and computing an estimate of a change of lung fluid relative to a baseline in lung(s) of the target patient according to the applied alternating current and measured voltage, wherein the applying, the measuring, and the computing the estimate of the change in lung fluid are iteratively executed for monitoring the target patient for accumulation of lung fluid while the feeding tube is in use. 1. An apparatus for differentiating between medical states of a subject , the apparatus comprising:a feeding tube;at least one first electrode disposed on a distal end of the feeding tube;at least one second electrode sized and shaped for contacting a surface of a skin of a subject; and (1) select a combination including a selected frequency spectrum of an alternating current and a selected electrode pair including the at least one first electrode and the at least one second electrode;', '(2) compute an impedance value according to voltage over the selected electrode pair and according to the alternating current applied at the selected frequency spectrum, and', '(3) compute a sub-impedance score according to the computed impedance value;', '(4) iterate (1), (2), and (3) for another combination;', '(5) differentiate between at least two medical states of the subject according to a plurality of the computed sub-impedance scores., 'a non-transitory memory having stored thereon a code which, when executed by at least one hardware processor of a ...

INTRAVASCULAR BLOOD FLOW MEASUREMENT USING DIFFERENTIAL PRESSURE PRINCIPLE AND AN EXPANDING FLOW SENSOR

A blood flow measurement system for measuring a blood flow quantity such as flow velocity or flow volume inside a blood vessel includes an intravascular blood flow measurement device with a body that comprises an expandable body section. A control unit sequentially provides a size control signal indicative of a respective one of the at least two predetermined expandable sizes to be assumed by the expandable body section. A pressure sensor unit measures respective sequences of blood pressure signals over a measuring time span defined with respect to a heart cycle period. A flow determination unit uses the values of cross sectional area of the expandable body section, the associated pressure signals and a known value of a density of blood, to calculate a value of a blood flow quantity inside the blood vessel based on Bernoulli's law. 1. An intravascular blood flow measurement device , comprising:a body suitable for placement inside a blood vessel of a living being and extending along a longitudinal direction;an expandable body section of the body, having a longitudinal extension in the longitudinal direction and a cross-sectional area perpendicular to the longitudinal direction that is controllably and reversibly expandable to assume a respective one of at least two different predetermined expanded sizes associated with at least two respective values of an expanded cross sectional area of the expandable body section;a controllable actuator arranged and configured to set the expandable body section to one of the at least two sizes; anda pressure sensor unit comprising at least one pressure sensor arranged on the body within the longitudinal extension of the expandable body section, the pressure sensor unit being configured to provide, for each of at least three values of cross sectional area of the body, including the at least two values of the expanded cross-sectional area of the expandable body section, a respective sequence of pressure signals indicative of a ...