КОМБИНИРОВАННАЯ СИСТЕМА ФОТОАКУСТИЧЕСКОГО И УЛЬТРАЗВУКОВОГО ФОРМИРОВАНИЯ ИЗОБРАЖЕНИЙ

Изобретение относится к медицинской технике, а именно с системам и способам формирования изображений при диагностике биообъектов. Система содержит лазер для генерации фотоакустических сигналов, преобразователь, канал ультразвукового сигнала, канал фотоакустического сигнала, блок оценки движения и блок объединения изображений. Способ объединения изображений образца, использующий устройство, заключается в освещении образца системой освещения, передаче ультразвуковых волн в образец ультразвуковым преобразователем, генерации оценки движения из ультразвуковых сигналов, принятых в разные моменты времени от одного и того же местоположения образца, генерации фотоакустического изображения из принятых фотоакустических сигналов и его коррекции вследствие движения, используя оценку движения. Использование изобретения позволяет проводить точное совмещение изображений, устранить артефакты и улучшить распознавание элементов при использовании фотоакустического формирования изображения в комбинации с ультразвуковым ...

ОПРЕДЕЛЕНИЕ МЕСТОПОЛОЖЕНИЯ ПОСРЕДСТВОМ БЕСПРОВОДНОЙ СВЯЗИ

Группа изобретений относится к медицинской технике, в частности к системе SY для определения местоположения схемы RTC радиочастотного транспондера, соответствующей модулю UEU ультразвукового излучателя. Схема RTC радиочастотного транспондера излучает радиочастотные сигналы, которые модулируются на основе принятых ультразвуковых сигналов, которые излучаются или отражаются модулем UEU ультразвукового излучателя. Местоположение схемы RTC радиочастотного транспондера относительно модуля UEU ультразвукового излучателя определяется на основе временной разности ΔT1между излучением ультразвукового сигнала модулем UEU ультразвукового излучателя и обнаружением модулем RFD радиочастотного детектора соответствующей модуляции в радиочастотном сигнале, излученном или отраженном схемой (RTC) радиочастотного транспондера. 12 н. и 19 з.п. ф-лы, 13 ил.

СИСТЕМА И СПОСОБ ДЛЯ ОТСЛЕЖИВАНИЯ ПРОНИКАЮЩЕГО ИНСТРУМЕНТА

Группа изобретений относится к медицинской технике, а именно к средствам отслеживания проникающего инструмента. Система содержит матрицу интраоперационных измерительных преобразователей, выполненную с возможностью генерировать сигналы из положений в матрице и обеспечивать одно или более изображений целевой области в реальном времени, проникающий инструмент, имеющий тело с по меньшей мере одним датчиком, установленным в целевом положении на теле проникающего инструмента, причем датчик реагирует на сигналы из положений в матрице, модуль обработки сигналов, выполненный с возможностью определять положение и ориентацию проникающего инструмента в соответствии с сигналами из положений в матрице, причем модуль обработки сигналов дополнительно выполнен с возможностью классифицировать среду, в которой позиционировано целевое положение, на основе реакции упомянутого по меньшей мере одного датчика на сигналы из положений в матрице, модуль наложения, выполненный с возможностью генерировать наложенное ...

УЛЬТРАЗВУКОВАЯ СИСТЕМА ВИЗУАЛИЗАЦИИ И СПОСОБ ДЛЯ ПРОЦЕДУРЫ НАВЕДЕНИЯ ПО ИЗОБРАЖЕНИЮ

... 1. Система ультразвуковой визуализации (10), включающая в себя:- ультразвуковой датчик (20), имеющий матрицу (21) измерительных преобразователей, выполненную с возможностью обеспечивать ультразвуковой сигнал приема,- блок (30) обработки объема B-режима, выполненный с возможностью генерировать объем (31) B-режима на основе ультразвукового сигнала приема,- блок (40) обработки изображений B-режима, выполненный с возможностью обеспечения текущего изображения (41) B-режима на основе объема (31) B-режима,- блок (95) сегментации сосуда, выполненный с возможностью создания трехмерной карты (51) сосудов путем выполнения методики сегментации сосуда,- память (50), выполненную с возможностью хранения предварительно полученной трехмерной карты (51) сосудов,- блок (60) совмещения, выполненный с возможностью совмещения ранее полученной трехмерной карты (51) сосудов с объемом (31) B-режима и выбирать часть (61) трехмерной карты сосудов, соответствующую текущему изображению (41) B-режима,- дисплей (16), ...

МОДЕЛИРОВАНИЕ СЦЕНЫ В РЕАЛЬНОМ ВРЕМЕНИ, ОБЪЕДИНЯЮЩЕЕ ФОРМИРОВАНИЕ ТРЕХМЕРНОГО УЛЬТРАЗВУКОВОГО И ДВУМЕРНОГО РЕНТГЕНОВСКОГО ИЗОБРАЖЕНИЙ

ОПРЕДЕЛЕНИЕ МЕСТОПОЛОЖЕНИЯ ПОСРЕДСТВОМ БЕСПРОВОДНОЙ СВЯЗИ

Device for determination of position of puncture needle in workspace of ultrasound probe for human body, has processor unit introducing stitch projection and penetration depth of needle together with image for representation of projection

The device has a lens projecting an object point in a workspace parallel to a midpoint beam on pixels of a charge coupled device camera (4), where light is received through the lens. Image information of the camera, incidence angle of a linear detection light beam and ultrasound image are supplied to a processor unit. The processor unit introduces a stitch projection in a position at an angle, an intersection point of the stitch projection in plane-sound plumbing and penetration depth of a puncture needle together with the ultrasound image for representation of the projection. An independent claim is also included for a kit comprising a determination device.

System zum patientenspezifischen Modellieren von Blutfluss

System zum Bestimmen von kardiovaskulären Informationen für einen Patienten, wobei das System Folgendes umfasst: wenigstens ein Computersystem, das konfiguriert ist, um: patientenspezifische Daten bezüglich einer Geometrie einer anatomischen Struktur des Patienten zu empfangen, wobei die anatomische Struktur wenigstens einen Abschnitt einer Mehrzahl an Koronararterien, die von einer Aorta ausgehen, beinhaltet; basierend auf den patientenspezifischen Daten ein dreidimensionales Modell zu erzeugen, das einen ersten Abschnitt der anatomischen Struktur repräsentiert, wobei der erste Abschnitt der anatomischen Struktur wenigstens den Abschnitt der Mehrzahl an Koronararterien beinhaltet; wenigstens teilweise basierend auf einer Masse oder einem Volumen des Myokardgewebes ein physikbasiertes Modell bezüglich einer Blutflusseigenschaft im ersten Abschnitt der anatomischen Struktur zu erzeugen; und wenigstens teilweise basierend auf dem dreidimensionalen Modell und dem physikbasierten Modell eine ...

Verfahren zum Bestimmen eines Flussparameters und Flussparameterbestimmungseinrichtung

Die Erfindung betrifft ein Verfahren zum Bestimmen eines Flussparameters, welcher einen Fluidfluss in einem Abschnitt eines Gefäßes betrifft, wobei das Verfahren die folgenden Schritte umfasst: – Bereitstellen eines Ultraschalldatensatzes, welcher einen abzubildenden Bereich, in dem sich das Gefäß befindet, betrifft, – Bereitstellen eines medizinischen Bilddatensatzes, welcher basierend auf einer elektromagnetischen Strahlung aufgenommen wurde und den abzubildenden Bereich betrifft, – Ermitteln einer Position-Information, mit welcher der Abschnitt des Gefäßes in dem Ultraschalldatensatz lokalisierbar ist, basierend auf dem medizinischen Bilddatensatz, – Bestimmen des Flussparameters, welcher den Fluidfluss in dem Abschnitt des Gefäßes betrifft, basierend auf dem Ultraschalldatensatz und basierend auf der Position-Information.

Method of and apparatus for non invasive medical imaging using waveform inversion

There is provided a non-invasive method of generating image data of intra-cranial tissue using ultrasound energy that is transmitted across a head of a subject throughthe skull of the subject. The method comprises the steps of: a) providing an ultrasound observed data set derived from a measurement of one or more ultrasound waveforms generated by at least one source of ultrasound energy, the ultrasound energy being detected by a plurality of receivers located at an opposing side of a region within the intra-cranial cavity with respect to at least one source such that thereceivers detect ultrasound waveforms from the source which have been transmitted through the skull and intra-cranial cavity, the observed data set comprising a plurality of observed data values; b) providing at least one starting model for at least a portion of the head comprising a skull component and a soft tissue component, the skull component comprising a plurality of model parameters representative of the physicalproperties ...

Method of and apparatus for non invasive medical imaging using waveform inversion

Multimodal imaging system and method

COMBINED PHOTO-ACOUSTIC AND ULTRASONIC REPRESENTATION SYSTEM

Transmissive imaging and related apparatus and methods

Ultrasound imaging devices and heads up displays, as well and systems utilizing both are described. In some embodiments, ultrasound data or images may be displayed on a heads up display, which may be a head-mounted display. One or more users may manipulate the images. Image capture devices and sensors may also be implemented.

Method and system for patient-specific modeling of blood flow

C:\Users\kll\AppData\Local\Temp12713 IDAOBAFC.DOCX-22 12/2015 Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Method and system for patient-specific modeling of blood flow

Abstract A system for determining cardiovascular information for a patient, the system comprising: at least one computer system configured to: receive patient specific data regarding a geometry of an anatomical structure of the patient; create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, the three-dimensional model representing at least one fluid flow inlet and at least one fluid flow outlet; create at least one boundary condition model representing fluid flow through at least one of the at least one inlet or the at least one outlet, based at least in part on modeling a condition of hyperemia; and determine first information regarding a blood flow characteristic within the anatomical structure of the patient based on the three dimensional model and the at least one boundary condition model. cCD Co co VC C C) C) f I co C, Loij 0~ u~ EtIt C3oI ...

APPARATUS AND METHOD FOR DIAGNOSING VESSEL OCCLUSION

Apparatus and methods for diagnosing conditions consistent with the presence of cranial blood vessel blockage and large vessel occlusions (LVO's) using the framework of a small head-harness that is transportable, field-expedient, and durable, A single pulse set using ultrasonic or near- infrared energy is broadcast into a patient's brain allowing the apparatus to perform an area scan of the brain and detect and decipher cranial blood vessel blockage and LVO signal patterns. The interpretation of the pattern lies within the internal programming which produces a binary signal as to whether an LVO is suspected or not.

HISTOTRIPSY SYSTEMS AND METHODS

A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.

A SPINAL NAVIGATION METHOD, A SPINAL NAVIGATION SYSTEM AND A COMPUTER PROGRAM PRODUCT

The invention relates to a spinal navigation method. The method comprises the steps of providing a MRI, X-ray or CT based two-dimensional image of the spine of a subject and generating an ultrasound two-dimensional image using an ultrasound imaging device on the spine of said subject. Further, the method comprises the steps of matching the ultrasound two-dimensional image to the MRI, X-ray or CT based two-dimensional image, and relating a pre-specified segment of a spinal profile in the MRI, X-ray or CT based two- dimensional image to a corresponding segment in the ultrasound two- dimensional image.

METHOD, SYSTEM AND APPARATUS FOR ADAPTIVE IMAGE ACQUISITION

A method of adaptive image acquisition includes obtaining a guide image of patient tissue; receiving an intraoperative image of a portion of the patient tissue from an imaging instrument; and storing the intraoperative image. The method includes comparing the intraoperative image with the guide image to identify at least one region of the guide image matching the intraoperative image; and determining whether the at least one region identified meets at least one accuracy criterion. When the at least one region meets the at least one accuracy criterion, the guide image is rendered with an indication of the at least one region on a display. When the at least one region does not meet the at least one accuracy criterion, the method includes receiving and storing a further intraoperative image; combining the further intraoperative image with the intraoperative image; and repeating the comparing and determining.

MULTIMODAL IMAGING SYSTEM, APPARATUS, AND METHODS

In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of LI and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In one embodiment, the system further includes an optical element configured to adjust the optical path length of the reference arm, wherein the optical element is in optical communication with the reference arm and wherein the optical element is transmissive or reflective.

Ultrasonic diagnostic equipment, image processing apparatus, and image processing method

Ultrasonic diagnostic equipment according to an embodiment of the invention comprises an acquisition unit (16a) and a detection unit (16b). The acquisition unit (16a) acquires fluid volume data indicating fluid information related to a fluid that flows in an area three-dimensionally scanned by ultrasonic waves. The detection unit (16b) uses the fluid information to detect an area, in which the fluid exists in the aforementioned area, and uses the detected area to detect the luminal area of a lumen in the volume data that is to be image-processed.

VISUAL TRACKING AND ANNOTATION OF CLINICALLY IMPORTANT ANATOMICAL LANDMARKS FOR SURGICAL INTERVENTIONS

STAND-ALONE ULTRASOUND UNIT FOR IMAGE GUIDED SURGERY

The present invention relates to a device for use in image guided surgery. A stand-alone ultrasound based device (1) is provided for use in an image guided surgery system, comprising: • an interface (20a) suitable for interaction with a first neuro- navigation unit (8) not based on a ultrasound modality, to receive from said nonultrasonic neuro-navigation unit, pre-operative static computer tomographic or magnetic resonance images and realtime information on the position and movement of tools and probes used for image guided surgery, and • ultrasound image display means (3), suitable for showing realtime 2D and acquired intra-operative volumetric ultrasound images including intraoperative positioning and movement of probes and tools, and being capable of displaying said ultrasound images superimposed on the static CT or MR images received via said interface.

SYSTEM AND METHOD FOR FUSING THREE DIMENSIONAL IMAGE DATA FROM A PLURALITY OF DIFFERENT IMAGING SYSTEMS FOR USE IN DIAGNOSTIC IMAGING

A multi-modality cancer screening and diagnosis system is provided that allows cancer screening and diagnosis of a patient using at least two different and sequential three-dimensional imaging techniques without patient repositioning. The system includes a first three-dimensional image acquisition device, a second three-dimensional image acquisition device having a probe with a transmitter mounted thereon, and a positioning paddle for positioning and immobilizing an object to be imaged during the cancer screening and diagnosis procedure. The positioning paddle is designed to facilitate visualization of the breast in both three-dimensional modalities without movement of the patient, and preferably is designed to position the patient with comfort during a diagnosis procedure which uses both imaging modalities.

SUBJECT-INFORMATION ACQUIRING APPARATUS

A subject-information acquiring apparatus includes a light source; a bed having a holder holding an examined portion of a subject, the bed being configured to support the subject; acoustic wave detectors configured to detect acoustic waves and output electric signals, the acoustic waves being generated when the examined portion is irradiated with light from the light source; a supporting member configured to support the acoustic wave detectors such that a direction of maximum reception sensitivity of at least some acoustic wave detectors and a direction of maximum reception sensitivity of other acoustic wave detectors different from the at least some acoustic wave detectors are different and are directed toward a specific region; and a signal processing unit configured to acquire information about the inside of the examined portion on the basis of the electric signals. The holder can be changed in shape to fit a shape of the examined portion.

Optical coherence tomography device for characterization of atherosclerosis with a 1.7 micron swept laser source

An OCT system with a swept light source centered around 1.7 μm for identifying atherosclerotic plaque and visualization of large lipid pool is provided. Advantages for using the 1.7 μm swept source laser include higher contrast between lipid and normal tissue and deeper penetration of the optical signals from the 1.7 μm swept source laser into the tissue. With deeper penetration into the tissue, more structural information from deep within the tissue is obtained. The present invention also features multimodality imaging systems that integrate additional imaging systems into the OCT system at 1.7 μm. As an example, an integrated 1.3 μm and 1.7 μm OCT system is provided which simultaneously generates OCT images using both the OCT systems which are used to characterize and differentiate the types of tissue.

IMAGE PROCESSING AND PATIENT-SPECIFIC MODELING OF BLOOD FLOW

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Image processing apparatus and image processing method

An image processing apparatus according to an embodiment comprises processing circuitry configured to acquire morphology image data including a site of a subject and function image data including the site, extract a blood vessel region that corresponds to a blood vessel included in the morphology image data, calculate a fluid index in the blood vessel region, and based on the fluid index, calculate a first function index as an index indicating a function of a tissue to which a nutrient is supplied from the blood vessel, acquire a second function index as an index indicating a function of the tissue based on the function image data, detect a mismatch between the first function index and the second function index, and determine a spatial region that corresponds to the mismatch in the site.

ACOUSTIC WAVE DIAGNOSTIC APPARATUS AND CONTROL METHOD OF ACOUSTIC WAVE DIAGNOSTIC APPARATUS

There are provided an acoustic wave diagnostic apparatus and a control method of an acoustic wave diagnostic apparatus capable of easily performing measurement and preventing differences in measurement results by users. An ultrasound diagnostic apparatus includes: a display unit that displays an acquired acoustic wave image; a measurement target determination unit that determines a measurement target included in the acoustic wave image displayed on the display unit; a measurement algorithm setting unit that sets a measurement algorithm based on the measurement target; and a measurement unit that measures the measurement target in the acoustic wave image based on the measurement algorithm set by the measurement algorithm setting unit and displays a measurement result on the display unit.

ENHANCED REALITY MEDICAL GUIDANCE SYSTEMS AND METHODS OF USE

Apparatus, system and methods are described for providing a health care provider (HCP) with an enhanced reality perceptual experience for surgical, interventional, therapeutic, and diagnostic use. The apparatus, system and methods make use of a combination of sensors and audio visual data to cross-correlate information, and present the correlated information to the HCP on to one or more platforms for use during a diagnostic, interventional, therapeutic, or surgical procedure.

ULTRASOUND IMAGING SYSTEM AND METHOD FOR ASSOCIATING A PHOTOGRAPHIC IMAGE WITH AN ULTRASOUND IMAGE

An ultrasound imaging system and method includes acquiring an ultrasound image, acquiring a photographic image, and associating, with a processor that is a component of the ultrasound imaging system, the photographic image with the ultrasound image. The ultrasound imaging system and method also includes display the ultrasound image and the photographic image on a display device after associating the photographic image with the ultrasound image.

SYSTEMS AND METHODS FOR DETECTING AND DISPLAYING BODY LUMEN BIFURCATIONS

A method for generating an ultrasound image includes receiving a sequence of intravascular ultrasound (IVUS) data obtained as an IVUS imager moves through a body lumen; identifying at least one bifurcation of the body lumen from the sequence of IVUS data; determining a bifurcation angle between two branches of the body lumen; and displaying a longitudinal view of the body lumen using the IVUS data and incorporating the bifurcation angle to angularly align portions of the longitudinal view corresponding to the two portions of the body lumen.

COMBINED PHOTOACOUSTIC AND ULTRASOUND IMAGING SYSTEM

The present disclosure provides for a system that is adapted to simultaneously display photoacoustic and ultrasound images of the same object. An image combiner can perform spatial and temporal interpolation of the two images before generating a combined image. The combined image is then displayed on a display such as an LCD or CRT. The system is able to use motion estimates obtained from the ultrasound data to enhance the photoacoustic image thereby increasing its apparent frame rate, registering consecutive frames in order to reduce artifacts. The system is capable of generating combined ultrasound and photoacoustic images which are registered spatially and temporally.

Systems, methods and computer readable storage media storing instructions for image-guided interventions based on patient-specific models

Systems, methods, and computer-readable storage media relate to generate an integrated image based on strain data and elastic model. The method may include determining, by a processor, a range of probe positions for placement of an ultrasound probe with respect to a patient based on strain data, the range of positions including a first position, a second position, and one or more positions there between. The method may also include acquiring 3D TRUS images of the patient at each of the one or more positions of the range and generating a patient specific biomechanical model based on the 3D TRUS images. The method may further include integrating the patient specific biomechanical model, the 3D TRUS images and MR images to generate an integrated image of the prostate. The methods, systems, and computer readable media can improve efficiency and accuracy of 3D TRUS and MR image registration, e.g., for image-guided interventions.

SYSTEMS AND METHODS FOR REGISTERING IMAGES OBTAINED USING VARIOUS IMAGING MODALITIES AND VERIFYING IMAGE REGISTRATION

Embodiments of the present invention provide systems and methods to detect a moving anatomic feature during a treatment sequence based on a computed and/or a measured shortest distance between the anatomic feature and at least a portion of an imaging system.

APPARATUS AND METHOD FOR SUPPORTING ACQUISITION OF AREA-OF-INTEREST IN ULTRASOUND IMAGE

The present disclosure relates to an apparatus for supporting acquisition of an area-of-interest in an ultrasound image. An apparatus for supporting acquisition of an area-of-interest in an ultrasound image according to an aspect of the present disclosure may comprise: at least one processor configured to convert coordinates of one or more areas-of-interest extracted from a first image to coordinates on a 3D model and collect the coordinates on the 3D model of the one or more areas-of-interest; when a second image is acquired, calculate coordinates on the 3D model corresponding to the acquired second image and match the second image onto the 3D model including the coordinates of the collected areas-of-interest; and provide guide information to allow acquisition of the collected areas-of-interest from the second image, using the matching result.

RADIOPAQUE ARRANGEMENT OF ELECTRONIC COMPONENTS IN INTRA-CARDIAC ECHOCARDIOGRAPHY (ICE) CATHETER

A system comprises an imaging device for imaging within a body of a patient. The imaging device comprises a flexible elongate member and an imaging assembly disposed at a distal portion of the flexible elongate member. The imaging assembly comprises in an array of imaging elements and a plurality of electronic components configured to perform an electrical function associated with imaging within the body of the patient using the array of imaging elements. Each of the plurality of electronic components is radiopaque such that the plurality of electronic components comprises a radiopaque pattern at the distal portion of the flexible elongate member. A method of imaging within a patient body comprises receiving a radiographic image representative of an ultrasound imaging device positioned within the patient body and determining an orientation of the ultrasound imaging device using a radiopaque pattern of a plurality of electronic components in the radiographic image.

INTRAVASCULAR DEVICES, SYSTEMS, AND METHODS UTILIZING PHOTOACOUSTIC, ULTRASOUND, AND OPTICAL COHERENCE TOMOGRAPHY IMAGING TECHNIQUES

Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic, ultrasound, and OCT modalities. In some embodiments, a medical sensing system includes a measurement apparatus configured to be placed within a vascular pathway and two optical emitters configured to emit optical pulses. The measurement apparatus may include a sensor array comprising two or more sensor modalities. The sensor array may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, transmit and receive ultrasound signals, and rotate around a longitudinal axis of the measurement device. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.

Control device, radiography system, medical imaging system, control method, and control program

A control device including: a control unit that, in a case in which continuous imaging that irradiates a breast of a subject with radiation emitted from a radiation source to capture a radiographic image in a compressed state in which the breast is compressed against an imaging table by a compression member and then captures an ultrasound image of the breast in the compressed state is performed, performs control to locate the radiation source at a non-facing position where the radiation source and the imaging table do not face each other.

Imaging system for generating a rendered image

The present application is directed to an imaging system having an imaging device for imaging at least a portion of an animal, wherein said imaging device is selected from a group consisting of X-ray computed tomography (CT), positron emission tomography (PET), single-photon emission computed tomography (SPECT), fluorescence and phosphorescence microscopy (FPM), infrared light spectroscopy (IR), Raman spectroscopy, ultrasound and any combination thereof. The system further comprises a photon transmitter of photons, introducible within the body of an animal; at least one imaging photon detector located either within or outside said animal, for detecting fluorescence excited within said animal by said transmitted photons; and an image processor adapted to superimpose said imaging device image and said photon detector image generating a rendered image of said at least a portion of said animal. Further, the present invention relates to a method of using the system.

Apparatus and method of image registration

A method for bringing an IVUS and an OCT image into register. In one embodiment, the method includes obtaining an IVUS image of an area of a lumen; obtaining an OCT image of the same area of the lumen; determining the same asymmetry in each of the IVUS and OCT images; and overlaying the IVUS and OCT images and rotating them with respect to one another until the asymmetry in each of the IVUS and OCT images are in register, and determining the angle of rotation that resulted in the registration. In another aspect, the invention relates to a probe for OCT and IVUS imaging. In one embodiment, the probe includes a sheath having a first end and a second end defining a lumen; a marker that is opaque to light and ultrasound located between the first end and second end; and an IVUS/OCT probe head positioned within the sheath.

СЕГМЕНТАЦИЯ КРУПНЫХ ОБЪЕКТОВ ИЗ НЕСКОЛЬКИХ ТРЕХМЕРНЫХ ВИДОВ

Группа изобретений относится к медицинской технике, а именно к средстам формирования ультразвуковых трехмерных изображений. Ультразвуковая система формирования изображения для обследования объекта в объеме содержит зонд получения ультразвуковых изображений, содержащий отслеживающее устройство положения зонда и предоставления положения точки наблюдения трехмерных ультразвуковых изображений, и процессор изображений, сконфигурированный для приема множества трехмерных ультразвуковых изображений и их соответствующих положений точки обзора и проведения сегментации объекта одновременно из множества трехмерных ультразвуковых изображений. Способ предоставления ультразвукового изображения осуществляется посредством системы, содержащей также машиночитаемый носитель, хранящий компьютерную программу выполнения этапов способа предоставления ультразвукового изображения объекта в объеме. Использование изобретений позволяет расширить арсенал средств для автоматизированной сегментации и регистрации трехмерных ...

ИНТЕГРАЦИЯ УЛЬТРАЗВУКОВОЙ И РЕНТГЕНОВСКОЙ МОДАЛЬНОСТЕЙ

УЛЬТРАЗВУКОВОЕ ИЗМЕРЕНИЕ ОБЪЕМНОГО ПОТОКА ДЛЯ АБЛЯЦИОННОЙ ТЕРАПИИ

... 1. Способ использования ультразвуковой информации для лечения абляцией патологии, содержащий:получение изображения планирования лечения патологии, подлежащей лечению посредством абляции, и одного или более кровеносных сосудов вблизи патологии;идентификацию патологии, подлежащей лечению посредством абляции, на ультразвуковом изображении;идентификацию одного или более кровеносных сосудов, которые находятся в непосредственной близости от патологии, посредством размещения формы поверхности в области, представляющей интерес, на ультразвуковом изображении;получение трехмерных ультразвуковых допплеровских данных из потока крови идентифицированных кровеносных сосудов посредством получения ультразвуковых допплеровских данных в пересечении потока одного или более кровеносных сосудов с использованием формы поверхности;вычисление количества крови, текущей через идентифицированные кровеносные сосуды, с использованием ультразвуковых допплеровских данных; иразработку плана лечения абляцией, который учитывает ...

System zum patientenspezifischen Modellieren von Blutfluss

System zum Ermöglichen der Bewertung einer Koronararterie eines Patienten basierend auf einem berechneten fraktionellen Flussreservewert, wobei das System Folgendes umfasst: wenigstens ein Computersystem, das konfiguriert ist, um: auf einem digitalen Anzeigegerät ein dreidimensionales Modell wenigstens eines Teils mehrerer Koronararterien, die von einer Aorta des Patienten abzweigen, anzuzeigen; auf dem Anzeigegerät eine erste fraktionelle Flussreserve anzuzeigen, die vom Computersystem für wenigstens eine der Koronararterien in dem dreidimensionalen Modell berechnet wurde; eine Eingabe hinsichtlich eines Behandlungsplans für die wenigstens eine der Koronararterien zu empfangen, wobei der Behandlungsplan ein Erweitern eines durch die wenigstens eine der Koronararterien definierten Lumens beinhaltet; und eine zweite fraktionelle Flussreserve für die wenigstens eine der Koronararterien zu berechnen und auf dem Anzeigegerät anzuzeigen, wobei das Berechnen der zweiten fraktionellen Flussreserve ...

Viskoelastizitätsmessung unter Verwendung einer amplitudenphasenmodulierten Ultraschallwelle

Eine viskoelastische Gewebeeigenschaft wird in vivo gemessen (32). Zur Gewinnung von weiteren Informationen und/oder zum Schätzen der Viskosität, des Schubmoduls, und/oder anderer Schubmerkmale wird eine amplituden- und phasenmodulierte Wellenform zu dem Gewebe gesendet (30). Die durch die Wellenform im Zeitverlauf verursachte Verschiebung umfasst Verschiebungen in Zusammenhang mit der Antwort auf verschiedene Frequenzen. Durch Untersuchung der Verschiebung in dem Frequenzbereich können eine oder mehr viskoelastische Eigenschaften für verschiedene Frequenzen berechnet werden (40). Der Frequenzgang kann die Gesundheit des Gewebes anzeigen.

Biomedical visualisation

Breast mapping and abnormality localization

Systems and methods for locating abnormalities within a breast and generating mappings of structures, such as ducts, within the breast. First imaging data may be acquired for a breast from a first imaging modality and second imaging data for the breast from a second imaging modality. The first imaging data is co-registered with the second imaging data, such that the first imaging data and the second imaging data share a common coordinate space. Based on the second imaging data, a plurality of structures within the breast are mapped to generate a mapping of the plurality of structures. From at least one of the first imaging data or the second imaging data, the abnormality in the breast is located. The mapping of the plurality of structures and the located abnormality in the breast may be concurrently displayed. A statistical analysis of the mapping of the breast structures may also be performed.

Method and system for patient-specific modeling of blood flow

C:\Users\kIl\AppData\Locl\Temp12713_1 DAOBAFC.DOCX-22 12 2015 Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Method for 3D imaging of mechanical assemblies transplanted into mammalian subjects

A medical imaging method is described for establishing implant configuration by measuring the positions and orientations of its components constrained by a defined kinematic relationship between them using stereo radiography images. The method allows the determination of a patient-specific implant configuration and enables accurate measurements of the pose of implant despite significant occlusions. The measurements obtained with this method can be used to determine the relative movement of an implant component relative to other components, bone or other landmark.

Method and system for patient-specific modeling of blood flow

C:\Users\kll\AppData\Local\Temp12713 IDAOBAFC.DOCX-22 12/2015 Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Ultrasound guided opening of blood-brain barrier

A system for delivering drugs or other molecules to the brain comprises an ultrasound imaging transducer configured to image structures such as the circle of Willis within a patient's head by way of a low attenuation acoustic window. The system includes a processor configured to register the ultrasound images to previously obtained images which also include the structures. The system includes ultrasound transducer elements operable to deliver ultrasound energy to a target region to cause the blood brain barrier to open. The system may include a drug delivery system that may be operated to deliver a drug to the patient in coordination with opening the blood brain barrier. Coordinates of the target region relative to the ultrasound imaging transducer are determined using registration information.

COMBINED PET/MR IMAGING SYSTEM AND APD-BASED PET DETECTOR FOR USE IN SIMULTANEOUS PET/MR IMAGING

APD-based PET modules are provided for use in combined PET/MR imaging. Each module includes a number of independent, optically isolated detectors. Each detector includes an array of scintillator (e.g LSO) crystals read out by an array of APDs. The modules are positioned in the tunnel of a MR scanner. Simultaneous, artifact-free images can be acquired with the APD-based PET and MR system resulting in a high-resolution and cost-effective integrated PET/MR system ...

IMAGING DEVICE

The invention provides an imaging device for use in medical interventions, such as surgery, comprising: an ultrasound probe to provide first image data; a cannula having a longitudinal internal channel and configured to be introduced into the human body; a direct vision camera arranged, at least partially, on or in the cannula to provide second image data; and a display device comprising at least one display to display an ultrasound image on the basis of the first image data and a direct vision image on the basis of the second image data.

METHOD AND SYSTEM OF DETERMINING PROBE POSITION IN SURGICAL SITE

One method to determine a position of a probe(112) in a surgical site with a plurality of reference structures may include receiving a three-dimensional image(300) of the surgical site generated before the probe(112) enters the surgical site and receiving a first two-dimensional image(206) generated by the probe(112) from a position within the surgical site. The three-dimensional image(300) is associated with a first coordinate system, and the first two-dimensional image(206) is associated with a second coordinate system. The method also includes acquiring registration to the plurality of reference structures based on the first two-dimensional image(206) to obtain a permissible set of probe pose parameters, extracting a second two-dimensional image(408) based on the permissible set of probe pose parameters from the three-dimensional image(300), and computing a correlation between the first two-dimensional image(206) and the extracted second two-dimensional image(408) to map the position ...

METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW

PROBE WITH OPTOACOUSTIC ISOLATOR

An optoacoustic probe including an ultrasound transducer array, an acoustic lens and a light path separated from the transducer array by an isolator to mitigate light energy from the light path from reaching the transducer array. The isolator can be formed from a mixture including a carrier material and between 10% and 80% by volume micro-bubbles. The isolator can be adapted to absorb, reflect or scatter light energy and absorb the optoacoustic response to light energy. In an embodiment, an optoacoustic probe also comprises an optical window and/or a diffuser, the isolator also separating the transducer array from these components.

SYSTEM AND METHOD FOR FUSING THREE DIMENSIONAL IMAGE DATA FROM A PLURALITY OF DIFFERENT IMAGING SYSTEMS FOR USE IN DIAGNOSTIC IMAGING

Method and system for patient-specific modeling of blood flow

Multi-mode imaging system, apparatus and method

환자별 혈류 모델링 방법 및 시스템

... 본 발명의 환자의 심혈관 정보를 결정하기 위한 시스템에 관한 것으로, 상기 시스템은 적어도 하나의 컴퓨터 시스템을 포함하며, 상기 적어도 하나의 컴퓨터 시스템은, 환자 심장의 기하 형태에 관한 환자별 데이터를 수신하도록 구성되고, 환자별 데이터에 기초하여 환자 심장의 적어도 일부분을 나타내는 3차원 모델을 생성하도록 구성되며, 환자 심장의 혈류 특성에 관한 물리학-기반 모델을 생성하도록 구성되고, 상기 3차원 모델 및 물리학-기반 모델에 기초하여 상기 환자 심장 내의 분획 혈류 예비력(FFR: Fractional Flow Reserve)을 결정하도록 구성된다.

METHOD FOR GENERATING A PET IMAGE DATA RECORD OF A MOVED EXAMINATION OBJECT AND FACILITY THEREFOR

METHODS AND SYSTEMS FOR ESTABLISHING PARAMETERS, PLAYBACK, AND ARTIFACT REMOVAL THREE-DIMENSIONAL IMAGING

The invention relates to systems and methods for the operation of three-dimensional imaging systems. Systems and methods of the invention are operable to display an image of tissue, receive a selection of points from within the image, establish a boundary corresponding to the selected points, and capture a three-dimensional image of the tissue within the designated boundary.

ULTRASONIC DIAGNOSTIC EQUIPMENT, IMAGE PROCESSING APPARATUS, AND IMAGE PROCESSING METHOD

Ultrasonic diagnostic equipment according to an embodiment of the invention comprises an acquisition unit (16a) and a detection unit (16b). The acquisition unit (16a) acquires fluid volume data indicating fluid information related to a fluid that flows in an area three-dimensionally scanned by ultrasonic waves. The detection unit (16b) uses the fluid information to detect an area, in which the fluid exists in the aforementioned area, and uses the detected area to detect the luminal area of a lumen in the volume data that is to be image-processed.

TOMOGRAPHIC IMAGE GENERATION DEVICE AND METHOD

... [Problem] To shorten the time needed to completely receive a photoacoustic signal and ultrasonic signal in a tomographic image generation device. [Solution] A trigger control circuit (28) outputs a light trigger signal and causes a subject to be irradiated with light. A sampling control circuit (29) outputs a sampling trigger signal. An A/D converting means (22) begins to sample a photoacoustic signal and stores the sampled photoacoustic signal in a reception memory (23). The trigger control circuit (28) outputs an ultrasonic trigger signal while the A/D converting means (22) continues sampling, and causes an ultrasonic wave to be sent to the subject. The A/D converting means (22) samples the reflective acoustic signal in connection with the photoacoustic signal, and stores the sampled reflective acoustic signal in the reception memory (23). A photoacoustic image generating means (25) and an ultrasonic image generating means (26) generate a photoacoustic image and an ultrasonic image on ...

MPR SLICE SELECTION FOR VISUALIZATION OF CATHETER IN THREE-DIMENSIONAL ULTRASOUND

A system employs an interventional tool (30), ultrasound imaging system and a multi-planar reformatting module (40). The interventional tool (30)has one or more image tracking points (31). The ultrasound imaging system includes an ultrasound probe (20)operable for generating an ultrasound volume image (22)of a portion or an entirety of the interventional tool (30)within an anatomical region. The multi-planar reformatting imaging module (40) generates two or more multi- planar reformatting images (41) of the interventional tool (30)within the anatomical region. A generation of the two multi-planar reformatting images (41)includes an identification of each image tracking point (31)within the ultrasound volume image (22), and a utilization of each identified image tracking point (31)as an origin of the multi-planar reformatting images (41).

ULTRASOUND IMAGING SYSTEM AND METHOD FOR IMAGE GUIDANCE PROCEDURE

The present invention relates to an ultrasound imaging system (10) comprising an ultrasound probe (20) having a transducer array (21) configured to provide an ultrasound receive signal. The system further comprises a B-mode volume processing unit (30) configured to generate a B-mode volume (31) based on the ultrasound receive signal, and a B-mode image processing unit (40) configured to provide a current B-mode image (41) based on the B-mode volume (31). The system further comprises a memory (50) configured to store a previously acquired 3D-vessel map (51). Also, the system comprises a registration unit (60) configured to register the previously acquired 3D-vessel map (51) to the B-mode volume (31) and to select a portion (61) of the 3D-vessel map corresponding to the current B-mode image (41). Further, the system comprises a display configured to display an ultrasound image (71) based on the current B-mode image (41) and the selected portion (61) of the 3D-vessel map (51). The present ...

Medical imaging device, tube voltage setting device, imaging control method, and recording medium storing imaging control program

A medical imaging device that includes: a press plate that presses a breast; an emitter that radiates radiation onto the breast; an acquisition section that acquires various information indicating a type of an acoustic matching member inserted between the press plate and the breast in cases in which ultrasound imaging of the breast is performed; and a setting section that sets a tube voltage of the emitter to a first tube voltage, in cases in which radiographic imaging of the breast is performed alone, and that sets the tube voltage of the emitter to a second tube voltage that is different from the first tube voltage, by employing the various information acquired by the acquisition section, in cases in which radiographic imaging and ultrasound imaging of the breast are performed consecutively with the acoustic matching member still inserted.

X-ray diagnosis apparatus and arm control method

An X-ray diagnosis apparatus according to an embodiment includes a calculating unit and a control unit. The calculating unit that calculates an angle between a specified position specified in an ultrasonic image generated through transmission and reception of ultrasonic waves by an ultrasound probe and a predetermined position in a radiographic space where a subject is radiographed based on information on a relative position between the radiographic space and a scanning space where the subject is scanned by the ultrasound probe. The control unit that controls an arm to move so that the subject is radiographed at the angle calculated by the calculating unit.

Methods and devices for registration of image data sets of a target region of a patient

A method for registering image data sets of a target region of a patient includes selecting a first anatomical structure only or at least partially only visible in the first image data set, and a second anatomical structure only or at least partially only visible in the second image data set, such that there is a known geometrical relationship between extended segments of the anatomical structures; automatically determining a first geometry information describing the geometry of at least a part of the first anatomical structure and a second geometry information describing the geometry of at least a part of the second anatomical structure, neither information being sufficient to enable registration of the image data sets on its own; automatically optimizing transformation parameters describing a rigid transformation of one of the anatomical structures with respect to the other and geometrical correspondences; and determining registration information from the optimized transformation parameters ...

MEDICAL IMAGING APPARATUS

The present invention relates to a medical imaging apparatus. The apparatus comprises an ultrasound acquisition unit including an ultrasound probe for acquiring ultrasound image data of a patient. An image data interface is provided for receiving 3D medical image data of the patient and a position determining unit for determining a position of the ultrasound probe. A calibration unit determines a transfer function between the ultrasound image data and the 3D medical image data at a plurality of positions (C) of the ultrasound probe and provides a corresponding plurality of calibrated transfer functions and calibration positions. A computation unit synchronizes the ultrasound image data and the 3D medical image data on the basis of a position of the ultrasound probe and the plurality of calibrated transfer functions, said computation unit is further adapted to weight the calibrated transfer functions on the basis of a position of the ultrasound probe. 111-. (canceled)12. A medical imaging apparatus comprising:an ultrasound probe configured to acquire ultrasound data;an electromagnetic tracker configured to determine a position of the ultrasound probe;a data base including three dimensional (3D) medical image data; and [{'sub': cal0', 'cal1, 'determine a transfer function between the ultrasound image data and the 3D medical image data at a plurality of positions (C) of the ultrasound probe and provide a corresponding plurality of calibrated transfer functions (T, T); and'}, 'synchronize the ultrasound image data and the 3D medical image data on based, at least in part, on the position of the ultrasound probe and the plurality of calibrated transfer functions., 'an image processing unit configured to13. The medical imaging apparatus of claim 12 , wherein the image processing unit is further configured to determine a plurality of calibration positions and synchronize the ultrasound image data and the 3D medical image data further based on the plurality of calibration ...

PHOTOACOUSTIC TRACKING AND REGISTRATION IN INTERVENTIONAL ULTRASOUND

An intraoperative registration and tracking system includes an optical source configured to illuminate tissue intraoperatively with electromagnetic radiation at a substantially localized spot so as to provide a photoacoustic source at the substantially localize spot, an optical imaging system configured to form an optical image of at least a portion of the tissue and to detect and determine a position of the substantially localized spot in the optical image, an ultrasound imaging system configured to form an ultrasound image of at least a portion of the tissue and to detect and determine a position of the substantially localized spot in the ultrasound image, and a registration system configured to determine a coordinate transformation that registers the optical image with the ultrasound image based at least partially on a correspondence of the spot in the optical image with the spot in the ultrasound image.

INTEGRATION OF ULTRASOUND AND X-RAY MODALITIES

A method for ultrasound image acquisition for tracking an object of interest in ultrasound image information includes receiving X-ray image information and ultrasound image information, determining, before the tracking, a spatial relationship between the X-ray image information and the ultrasound image information, detecting an object of interest in the X-ray image information and steering two-dimensional ultrasound image acquisition such that the object of interest is within an ultrasound image plane.

SENSOR COORDINATE CALIBRATION IN AN ULTRASOUND SYSTEM

A medical imaging apparatus includes: an ultrasound probe to transmit and receive an ultrasound signal to obtain an ultrasound image of an object; a sensor coupled to the ultrasound probe to provide a position information related to an ultrasound imaging position in the object; and a processor to extract a certain anatomical feature from the ultrasound image and the certain anatomical feature from a medical image, perform a first registration between the medical image and the ultrasound image by matching the certain anatomical feature in the ultrasound image the certain anatomical feature in the medical image, perform a second registration between the sensor and the medical image based on the position information and the first registration, and control a display to display a portion of the medical image corresponding to the ultrasound imaging position based on at least one of the first registration and the second registration.

Non-Invasive Convergent Heating Treatment

The invention relates to medical therapy of detrimental lesions. A system treats with non-invasive arrays of non-ionizing energy-radiation sources. The external sources focus energy dose distribution to a selected volume in a body. Energy output is directed towards a pathologic location and quenched around other sites or healthy tissue. Beam aiming is done without source movement. Targeted, volumetrically discrete energy deposition can beneficially manipulate lesions within the body. The purpose of the focused and enhanced energy deposition is to repair or disable pathologic physiology or structures, nerve pathways, extracellular fluid, and misfolded proteins. Locally augmented energy is used to enhance immunity, release pharmaceutical compounds from energy-sensitive vesicles and reconfigure or eliminate misfolded proteins and their aggregates. Targeted tissue may have enhanced sensitivity to received energy via a non-ionizing-radiation, treatment-localizing agent. This system optimizes ...

ULTRASONIC DEVICE FOR DENTAL IMPLANT NAVIGATION

The present invention providing a real-time positioning ultrasonic system that locates the dental implant drill bit relative to placed reference points or fiducial markers, and guides the drill entry point and angular trajectory, so that drilling is effected in the most optimum location in the jaw bone, as planned based on pre-surgery cone-beam computed tomography scans.

MRI IMAGE FUSION METHODS AND USES THEREOF

A method for fusing a pre-operative MRI prostate image to an intra-operative TRUS or CT prostate image according to a least-cost affine transformation of the MRI contour onto the TRUS or CT contour, with smooth non-linear warping adjustment. MRI and CT processing may be performed as a pre-operational procedure for increased efficiency, while TRUS may be performed concurrent with a surgical procedure.

METHODS FOR USING RADIAL ENDOBRONCHIAL ULTRASOUND PROBES FOR THREE-DIMENSIONAL RECONSTRUCTION OF IMAGES AND IMPROVED TARGET LOCALIZATION

A method, including obtaining at least one preoperative image from an imaging modality; identifying, on the at least one preoperative image, at least one element located within an area of interest; obtaining at least one intraoperative image; highlighting the at least one element on the at least one intraoperative image; navigating a radial endobronchial ultrasound probe to the area of interest using the at least highlighted at least one element; acquiring a plurality of radial endobronchial ultrasound images; extracting a plurality of two-dimensional representations of the element, each of the plurality of two-dimensional representations of the element being extracted from a corresponding one of the plurality of radial endobronchial ultrasound images; reconstructing a three-dimensional representation of the element from the plurality of two-dimensional representations of the element; and projecting a two-dimensional projection of the three-dimensional representation of the element on at ...

SENSOR COORDINATE CALIBRATION IN AN ULTRASOUND SYSTEM

A medical imaging apparatus includes an ultrasound probe to transmit and receive an ultrasound signal to obtain an ultrasound image of an object; a sensor coupled to the ultrasound probe to provide a position information related to an ultrasound imaging position in the object; and a processor to extract a certain anatomical feature from the ultrasound image and the certain anatomical feature from a medical image of the object acquired by an imaging modality different from an ultrasound apparatus, perform a first registration between the medical image and the ultrasound image based on the certain anatomical feature, perform a second registration between the sensor and the medical image based on the position information and the first registration, and control a display to display a portion of the medical image corresponding to the ultrasound imaging position based on the second registration. 1. A medical imaging apparatus comprising:an ultrasound probe to transmit and receive an ultrasound signal to obtain an ultrasound image of an object;a sensor coupled to the ultrasound probe to provide a position information related to an ultrasound imaging position in the object; anda processor to extract a certain anatomical feature from the ultrasound image and the certain anatomical feature from a medical image of the object acquired by an imaging modality different from an ultrasound apparatus, perform a first registration between the medical image and the ultrasound image based on the certain anatomical feature, perform a second registration between the sensor and the medical image based on the position information and the first registration, and control a display to display a portion of the medical image corresponding to the ultrasound imaging position based on the second registration.2. The medical imaging apparatus of claim 1 , wherein the processor obtains a first sample point of the certain anatomical feature extracted from the medical image of the object claim 1 , ...

DEVICES AND METHODS FOR STRATIFICATION OF PATIENTS FOR RENAL DENERVATION BASED ON INTRAVASCULAR PRESSURE AND CROSS-SECTIONAL LUMEN MEASUREMENTS

Devices, systems, and methods for pulse wave velocity determination are disclosed. The apparatus includes an intravascular device that can be positioned within a renal artery. The intravascular device includes a flexible elongate member having a proximal portion and a distal portion. A pressure sensor can be coupled to the distal portion of the flexible elongate member. The pressure sensor can monitor a pressure within the renal artery. At least one imaging element can be coupled to the distal portion of the flexible elongate member. The imaging element can monitor a cross-sectional area of the renal artery. A processing system in communication with the intravascular device can control the monitoring of the pressure within the renal artery and the cross-sectional area of the renal artery. The processor can receive pressure data and cross-sectional area data and determine a pulse wave velocity of fluid within the renal artery.

Medical imaging system

A medical imaging system acquires a first medical image of a breast as an object using a first imaging apparatus in a state in which the breast is fixed, captures a second medical image of the breast as the object using a second imaging apparatus having a different imaging principle from the first imaging apparatus in a state in which the fixation of the breast is maintained, sets a period for which the second medical image is captured and a period for which the first medical image is analyzed so as to at least partially overlap each other in a case in which the first medical image is analyzed to detect a region of interest, and outputs positional information such that a region-of-interest image having the region of interest as a main object is captured in a case in which the region of interest has been detected.

METHOD AND SYSTEM FOR RECONSTRUCTING A THERMOACOUSTIC IMAGE

TISSUE IMAGING SYSTEM

The tissue imaging system incorporates an integrated X-Ray and Ultrasound Imaging system. The X-Ray system is used for imaging and generating a 3D Volume of the extracted tissue sample (specimen). The Ultrasound Imaging system is used for imaging the body area of interest of the patient from which the tissue sample is to be extracted. On the display of the system, the physician draws contours on the area of interest and the same is displayed as a 3D Volume. A 3D volume of the extracted tissue is generated using the x-ray imaging sub-system. Quantitative analysis is performed on the two 3D volumes (extracted tumor x-ray imaging and the contoured ultrasound imaging) to determine the difference between the contoured and the surgically extracted specimen to assist the physician in determining if further surgical intervention is required.

УЛЬТРАЗВУКОВАЯ СИСТЕМА ВИЗУАЛИЗАЦИИ И СПОСОБ ДЛЯ ПРОЦЕДУРЫ НАВЕДЕНИЯ ПО ИЗОБРАЖЕНИЮ

Группа изобретений относится к медицинской технике, а именно к ультразвуковым системам визуализации. Система ультразвуковой визуализации включает ультразвуковой датчик, имеющий матрицу измерительных преобразователей, который обеспечивает ультразвуковой сигнал приема, блок обработки объема B-режима, который генерирует объем B-режима на основе ультразвукового сигнала приема, блок обработки изображений B-режима, обеспечивающий текущее изображение B-режима на основе объема B-режима, блок сегментации сосуда, создающий трехмерную карту сосудов путем выполнения методики сегментации сосуда до вставки инвазивного медицинского устройства во время процедуры наведения по ультразвуковому изображению, память, которая хранит предварительно полученные трехмерные карты сосудов, блок совмещения, совмещающий ранее полученные трехмерные карты сосудов с объемом B-режима и выбирающий части трехмерной карты сосудов, которые соответствуют текущему изображению B-режима, причем блок совмещения выполнен с возможностью ...

ИНТЕГРАЦИЯ УЛЬТРАЗВУКОВОЙ И РЕНТГЕНОВСКОЙ МОДАЛЬНОСТЕЙ

Группа изобретений относится к медицинской технике, а именно к средствам отслеживания интересующего объекта по информации ультразвукового изображения. Способ получения ультразвуковых изображений содержит прием информации рентгеновского изображения и информации ультразвукового изображения, причем взаимное пространственное расположение информации рентгеновского изображения и информации ультразвукового изображения задано, обнаружение интересующего объекта по информации рентгеновского изображения, управление получением двумерного ультразвукового изображения так, чтобы интересующий объект находился в первой плоскости ультразвукового изображения, и при этом первая плоскость ультразвукового изображения содержит рентгеновский источник, ультразвуковой источник и проекцию интересующего объекта в информации рентгеновского изображения. Система для получения ультразвуковых изображений содержит рентгеновскую систему, имеющую рентгеновский источник и детектор рентгеновского излучения, и ультразвуковую ...

АППАРАТ МЕДИЦИНСКОЙ ВИЗУАЛИЗАЦИИ

УСТРОЙСТВО МЕДИЦИНСКОЙ ВИЗУАЛИЗАЦИИ

КОМБИНИРОВАННАЯ СИСТЕМА ФОТОАКУСТИЧЕСКОЙ И УЛЬТРАЗВУКОВОЙ ВИЗУАЛИЗАЦИИ

... 1. Система визуализации, содержащая: ! (a) средство для формирования фотоакустических сигналов; ! (b) по меньшей мере, первый преобразователь, выполненный с возможностью: (i) передачи ультразвуковых волн; (ii) приема ультразвуковых сигналов, порожденных ультразвуковыми волнами; и (iii) приема фотоакустических сигналов, сформированных средством формирования фотоакустических сигналов; ! (c) блок оценки параметров движения, выполненный с возможностью оценки параметров движения на основе ультразвуковых сигналов; и ! (d) блок объединения изображений, выполненный с возможностью приема и объединения ультразвуковых данных, фотоакустических данных и данных блока оценки параметров движения, сформированных из принятых ультразвуковых и фотоакустических сигналов и блоком оценки параметров движения, и введения поправки на движение, для формирования, по меньшей мере, фотоакустического изображения. ! 2. Комбинированная система визуализации, содержащая: ! (a) средство для формирования фотоакустических сигналов ...

Bestimmen der räumlichen Lage und Orientierung der Wirbelkörper der Wirbelsäule

Vorrichtung zum Bestimmen der räumlichen Lage und Orientierung eines Beckens und / oder der knöchernen Strukturen der Schulter-Arm-Region und / oder der Wirbelkörper einer Wirbelsäule (10) eines Wirbeltiers (170), umfassend:a) ein Röntgenaufnahmegerät (100 und 210) mit einem Röntgen-Strahlengang;b) ein optisches Aufnahmegerät (120-150, 180) zum Aufnehmen von Oberflächendaten (30), wobei das optische Aufnahmegerät einen optischen Strahlengang hat;c) ein optisches Element (150) zum Überlagern des optischen Strahlengangs und des Röntgen-Strahlengangs (160);d) Mittel zum Auslösen sowohl einer Aufnahme mit dem Röntgenaufnahmegerät als auch mit dem optischen Aufnahmegerät derart, dass die beiden Aufnahmen mit einem maximalen zeitlichen Abstand von einer Sekunden erfolgen;e) Mittel zum Überlagern der aufgenommenen mindestens einen Röntgenaufnahme und der optisch gewonnenen Oberflächendaten (30); undf) Mittel zum Berechnen eines dreidimensionalen Modells (50) aus den optisch gewonnenen Oberflächendaten ...

Video-basiertes Mono-Kamera-Navigationssystem

Die Erfindung betrifft ein Verfahren zur Herstellung eines video-basierten Mono-Kamera-Navigationssystems. Das System ist in der Lage, unter Nutzung einer einzigen Kamera und Markern versehen mit unterschiedlichen Geometrien und Farben die Ortsinformation eines Objektes zu bestimmen. Zu dem System gehören eine Videokamera (5), eine elektronische Datenverarbeitungsanlage (8), ein mit einem bestimmten Muster und einer bestimmten Farbe versehener erster Marker (6), der sich in einer bekannten festen Position zu einem ortsfesten oder ortsveränderlichen Objekt (10) befindet, und ein zweiter Marker (7), der mit einem anderen bestimmten Muster und einer anderen bestimmten Farbe versehen ist und mit einem lageveränderlichen Gegenstand (2), dessen jeweils eingenommene Lage in einem Messbereich erfasst werden soll, verbunden ist. Dieses System hat gegenüber bekannten Lösungen den Vorteil, dass nur eine Videokamera (5) benötigt wird und an diese Kamera (5) nur solche technischen Ansprüche gestellt ...

Multimodal imaging system and method

An imaging assembly, system and method for automated multimodal imaging of biological tissue is provided. It finds particular application in the medical imaging of breast tissue. An optical 3D scanner is included to determine the shape of the surface of tissue and output a plurality of 3D coordinates thereof. An X-ray generator is included for sequentially radiating X-rays at a plurality of angles, through the tissue, toward an X-ray detector positioned below the patient. An articulated arm holding an ultrasound transducer at an end thereof automatically moves the ultrasound transducer along a path defined by the obtained 3D coordinates for ultrasound imaging of the breasts while maintaining the transducer in contact with the surface at an orientation required for ultrasound imaging.

Biomedical visualisation

Systems and methods for improving soft tissue contrast, multiscale modeling and spectral CT

Systems and methods for improving soft tissue contrast, characterizing tissue, classifying phenotype, stratifying risk, and performing multi-scale modeling aided by multiple energy or contrast excitation and evaluation are provided. The systems and methods can include single and multi-phase acquisitions and broad and local spectrum imaging to assess atherosclerotic plaque tissues in the vessel wall and perivascular space.

PROCEDURE AND DEVICE FOR the REGISTRATION, VERIFICATION OF AND REFERENCE TO BODY ORGANS (N)

Multimodal imaging system, apparatus, and methods

In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of LI and a sample arm that includes a second optical fiber of length of L2 and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L2 is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In one embodiment, the system further includes an optical element configured to adjust the optical path length of the reference arm, wherein the optical element is in optical communication with the reference arm and wherein the optical element is transmissive or reflective.

System and method for diagnostic vector classification support

The diagnostic vector classification support system and method disclosed herein may both reduce the time and effort required to train radiologists to interpret medical images, and provide a decision support system for trained radiologists who, regardless of training, have the potential to miss relevant findings. In an embodiment, a morphological image is used to identify a zone of interest in a co-registered functional image. An operator's grading of a feature at least partially contained within the zone of interest is compared to one or more computer-generated grades for the feature. Where the operator and computer-generated grades differ, diagnostic support can be provided such as displaying additional images, revising the zone of interest, annotating one or more displayed images, displaying a computer-generated feature grade, among other possibilities disclosed herein.

Ultrasound device with video display capability and associated devices, systems, and methods

A method of operating a portable ultrasound device to display digital video information from a video camera includes loading instructions into a memory of the device that configures processor electronics to process digital video signals. When a request for the video is received, the ultrasound device can ready itself to receive digital video information and display an image at a display of the ultrasound device based at least in part on the video information. In one embodiment, the video modality is enabled when the portable ultrasound device detects that the digital camera device has been connected to a port.

Method and System For Patient-Specific Modeling of Blood Flow

Embodiments include a system for planning treatment for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of an anatomical structure of the patient, create a three-dimensional model representing at least a portion of the anatomical structure of the patient based on the patient-specific data, and determine a first fractional flow reserve within the anatomical structure of the patient based on the three-dimensional model and information regarding a physiological condition of the patient. The at least one computer system may be further configured to receive input from a user regarding a plan of treatment, modify the physiological condition of the patient based on the received input, and determine a second fractional flow reserve within the anatomical structure of the patient based on the modified physiological condition of the patient.

Medical image display apparatus and method for displaying medical images

A medical image display apparatus for displaying medical images of a biological tissue includes a physical quantity calculator that calculates a first physical quantity related to elasticity of the biological tissue, and a display image control unit that displays a first elastic image having a display form corresponding to the first physical quantity calculated by the physical quantity calculator and a second elastic image having a display form corresponding to a second physical quantity related to elasticity of the biological tissue calculated by other another medical image display apparatus as the medical images. The display image control unit displays images in which portions having a same elasticity in the biological tissue in a same display form as the first and second elastic images.

System and method to illustrate ultrasound data at independent displays

An ultrasound imaging system is provided that comprises a beamformer, a first processor, and a second processor. The beamformer receives an ultrasound image data acquired by a transducer probe. The first processor processes the ultrasound image data communicated from the beamformer so as to create a first illustration at a first interface to show to a user of the ultrasound imaging system. The second processor processes the ultrasound image data communicated from the beamformer so as to create a second illustration at a second interface to show to a patient of the ultrasound imaging system. The first processor performs different processing steps compared to the second processor such that the first illustration at the first interface is different than the second illustration at the second interface.

Information processing apparatus, information processing system, information processing method, and computer-readable recording medium

An information processing apparatus includes a display control unit configured to control display of a cross-sectional image along a first cross section passing through a subject and a cross-sectional image along a second cross section passing through a specified position of the subject; an acquisition unit configured to acquire an inclination of the first cross section with respect to the subject; and a setting unit configured to set the second cross section as a cross section that is parallel to the first cross section and that passes through the specified position on the basis of the acquired inclination.

Ultrasound diagnostic apparatus and method of displaying medical image thereof

An ultrasound diagnostic apparatus is provided. The ultrasound diagnostic apparatus includes an input device configured to receive an input to display a cross-section of a reference medical image, wherein the reference medical image identifies a location of the cross-section in relation to a subject, and includes a characteristic region, and a reference medical image display control device configured to display the cross-section of the reference medical image based on volume data of the reference medical image previously acquired, the cross-section displayed according to the input.

Method and system for patient-specific modeling of blood flow

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Method and system for patient-specific modeling of blood flow

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

MEDICAL IMAGING METHOD AND SYSTEM

In an imaging procedure, sound pressure is generated by applying ultrasound to the region to be imaged in order to cause a deformation of tissue therein from at least one acquired ultrasound image data set, first data are determined that represent, with spatial resolution, the deformation of the tissue as a reaction to the sound pressure. At least one magnetic resonance image data set is acquired, from which second data are determined that represent, with spatial resolution, the deformation of the tissue as a reaction to the sound pressure. The at least one ultrasound image data set and the at least one magnetic resonance image data set are brought into registration with each other by a comparison of the first data and the second data. 1. A method for medical imaging , comprising:subjecting tissue in a region of an examination subject to sound pressure by applying ultrasound to said region, in order to cause a deformation of said tissue in said region as a reaction to said sound pressure;operating an ultrasound imaging device to acquire at least one ultrasound image data set of said region during or after subjecting said tissue to said sound pressure;in a processor, determining first data from said at least one ultrasound image data set that represent, with spatial resolution, said deformation of said tissue as a reaction to said sound pressure;operating a magnetic resonance imaging device to acquire at least one magnetic resonance image data set of said region during or after said application of said sound pressure to said tissue;in said processor, determining second data from said at least one magnetic resonance image data set that represent, with spatial resolution, said deformation of said tissue as a reaction to said sound pressure; andin said processor, bringing said at least one ultrasound image data set and said at least one magnetic resonance image data set into registration with each other based on a comparison of said first data and said second data with ...

System For Diagnosing and Identifying Genetic Features, Genetic and Congenital Syndromes And Developmental Abnormalities

The invention is a system for diagnosing and identifying of genetic characteristics, genetic syndromes, congenital syndromes, developmental and exposure related syndromes, and veterinary breed characteristics in fetuses, children and adults, in humans and animals. The system takes a set of facial anatomical measurements of an individual target and biological relatives of the individual target, normalizes the facial anatomical measurements, and compares the normalized measurements with a database of set of anatomical features associated with a desired diagnostic data set. 1. A system for the identification and diagnosis of genetic features , genetic syndromes , congenital and developmental abnormalities of a human or animal target , the system comprising:a first data collection module, capable of obtaining facial anatomical measurements of the target;a database of data correlating facial anatomical measurements with a diagnostic data set;a second data collection module, capable of obtaining facial anatomical measurements of biological relatives of the target;a data filter module, capable of comparing the target's facial anatomical measurements with the facial anatomical measurements of the biological relatives to produce a filtered set of target facial measurements;a data processing module, capable of comparing the filtered set of target facial anatomical measurements with the database; anda reporting module, capable of providing a report of the comparison.2. The system of claim 1 , where the diagnostic data set comprises genetic characteristics.3. The system of claim 1 , where the diagnostic data set comprises genetic syndromes.4. The system of claim 1 , where the diagnostic data set comprises congenital syndromes.5. The system of claim 1 , where the diagnostic data set comprises developmental and exposure related syndromes.6. The system of claim 1 , where the diagnostic data set comprises veterinary breed characteristics.7. The system of claim 1 , further ...

Image processing apparatus, imaging system, and image processing method

An image processing apparatus comprises a selection unit configured to select at least a first region of interest from regions of interest set in an imaging target, an image obtainment unit configured to obtain a first image representing the imaging target, and a second image from an imaging apparatus that images at least part of the imaging target, an information obtainment unit configured to obtain information of an existence range, and a display control unit configured to add, to the first image, displays representing positions of set regions of interest, and when the second image contains the existence range of the selected region of interest, display the existence range of the selected region of interest on the second image, and when the second image contains the existence range of an unselected region of interest, hide the existence range information.

Ultrasonic probe and inspection apparatus equipped with the ultrasonic probe

An ultrasonic probe includes a light irradiating portion configured to radiate light for generating ultrasonic waves from a light absorber, an ultrasonic transducing portion configured to transduce the ultrasonic waves to an electric signal, and a light guide member configured to introduce light from a light source to the light irradiating portion. A light irradiating region of the light irradiating portion is included within an ultrasonic receiving region of the ultrasonic transducing portion.

SYSTEM AND METHOD FOR USING MEDICAL IMAGE FUSION

A method and system for diagnosis and treatment of medical conditions. The method includes communicating MRI, CT, PET and/or ultrasound image data, and fusing such data using an image-guided biopsy system. It further includes using such fused images in conjunction with the image-guided biopsy system for performing diagnosis and treatment procedures. 1. A method for guiding a procedure , comprising:annotating regions of a medical imaging scan to acquire a first image of an organ;modeling the medical imaging scan as an imaging scan volumetric model;communicating the annotations of the medical imaging scan and the volumetric model through a communication network to an ultrasound center;processing ultrasound data from an ultrasound scanner at the ultrasound center to form an ultrasound volumetric model of the organ;fusing the medical imaging volumetric model with the ultrasound volumetric model into a fused image based on predetermined anatomical features, wherein at least one of the medical imaging volumetric model and the ultrasound volumetric model is deformed according to a tissue model such that the predetermined anatomical features of the medical imaging volumetric model and the ultrasound volumetric model are aligned; andmerging real-time ultrasound data with the fused image and annotated regions at the ultrasound center, such that that the annotated regions of the medical imaging scan are presented on a display maintaining anatomically accurate relationships with the real-time ultrasound data.2. The method according to claim 1 , wherein the modeling comprises a segmentation of anatomical features.3. The method according to claim 1 , further comprising transforming at least one of the imaging scan volumetric model and the ultrasound volumetric model to a common physical coordinate system such that the common anatomy of the organ is in a corresponding coordinate position.4. The method according to claim 3 , further comprising determining a projection of the ...

Multi-modality image acquisition

One or more techniques and/or systems described herein provide for generating a radiographic image and ultrasound image depicting parallel planes of an object under examination and may be used in conjunction with radiographic or ultrasound techniques known to those in the field (e.g., x-ray tomosynthesis, computed tomography ultrasound imaging, etc.). An ultrasound frontend component is configured to transmit ultrasound waves in a direction substantially parallel to a trajectory of radiation. In one example, one or more radiographic images of an object are spatially coincident to one or more ultrasound images of the object in the same position and/or geometric shape/volume, and the images may be combined to generate a combined image depicting features of the ultrasound image (e.g., the sensitivity of the ultrasound image) and features of the radiographic image (e.g., the morphological details of the radiographic image).

Breast measurement apparatus

A breast measurement apparatus comprises a receptacle for surrounding a breast; a plurality of optical fibers for irradiating the breast with examination light and detecting transmitted scattered light from the breast; an inner image generation unit for generating an optical CT image concerning the breast according to a detection signal of the transmitted scattered light; an ultrasonic probe, arranged so as to face the inside of the receptacle, for scanning the breast with an ultrasonic wave and receiving a reflected wave from the breast; an image generation unit for generating an ultrasonic image concerning the breast according to the reflected wave; and a mechanism for injecting and discharging a liquid interface agent into and from the inside of the receptacle.

System and method for dynamically varying the angle of light transmission in an optoacoustic imaging system

An optoacoustic probe includes an optical window, a light path, an acoustic lens and an ultrasound transducer array. The light path operatively connects a light source to the probe, and is adapted to transmit light through the optical window at an angle of light transmission. The ultrasound transducer array includes ultrasound transducer elements, and has the inner surface of the acoustic lens at its active end. The probe is enabled to vary the angle of light transmission responsive to at least one command. In an embodiment, the light source generates a light pulse at at least one predominant wavelength. The light path may comprise at least first plurality of optical fibers. A control and processing system may be provided that is capable of pulsing the light source, causing the probe to transmit ultrasound, receiving and processing optoacoustic and ultrasound data, and controlling the operation of the system. An electrical path operatively connecting the control and processing system to the probe transmits and receives ultrasound data, and receives optoacoustic data. The control and processing system may be capable of transmitting at least one command to the probe via a control line such that the probe is caused to vary an angle of light transmission of the first plurality of optical fibers responsive to a first one of the at least one commands.

3D TRANSURETHRAL ULTRASOUND SYSTEM FOR MULTI-MODAL FUSION

A three-dimensional transurethral ultrasound system includes a transurethral ultrasound probe, an ultrasound data processor configured to communicate with the transurethral ultrasound probe to receive ultrasound signals from the transurethral ultrasound probe and to output ultrasound imaging signals for three-dimensional ultrasound images of at least a portion of a patient's prostate, and a display system configured to communicate with the ultrasound data processor to receive the ultrasound imaging signals and to render three-dimensional ultrasound images of the at least the portion of the patient's prostate from the ultrasound imaging signals. 1. A three-dimensional transurethral ultrasound system , comprising:a transurethral ultrasound probe;an ultrasound data processor configured to communicate with said transurethral ultrasound probe to receive ultrasound signals from said transurethral ultrasound probe and to output ultrasound imaging signals for three-dimensional ultrasound images of at least a portion of a patient's prostate; anda display system configured to communicate with said ultrasound data processor to receive said ultrasound imaging signals and to render three-dimensional ultrasound images of said at least said portion of said patient's prostate from said ultrasound imaging signals.2. A three-dimensional transurethral ultrasound system according to claim 1 , further comprising an image registration unit configured to receive preoperative image data and register said preoperative image data with said three-dimensional ultrasound images.3. A three-dimensional transurethral ultrasound system according to claim 1 , wherein said preoperative image data is at least one of magnetic resonance imaging data claim 1 , x-ray computed tomography data claim 1 , positron emission tomography data claim 1 , single-photon emission computed tomography data claim 1 , or ultrasound data.4. A three-dimensional transurethral ultrasound system according to claim 1 , wherein ...

System and Method for Real-Time Ultrasound Guided Prostate Needle Biopsy Based on Biomechanical Model of the Prostate from Magnetic Resonance Imaging Data

A method and system for real-time ultrasound guided prostate needle biopsy based on a biomechanical model of the prostate from 3D planning image data, such as magnetic resonance imaging (MRI) data, is disclosed. The prostate is segmented in the 3D ultrasound image. A reference patient-specific biomechanical model of the prostate extracted from planning image data is fused to a boundary of the segmented prostate in the 3D ultrasound image, resulting in a fused 3D biomechanical prostate model. In response to movement of an ultrasound probe to a new location, a current 2D ultrasound image is received. The fused 3D biomechanical prostate model is deformed based on the current 2D ultrasound image to match a current deformation of the prostate due to the movement of the ultrasound probe to the new location. 1. A method comprising , comprising:segmenting a prostate in a 3D ultrasound image of a patient;fusing a reference patient-specific biomechanical model of the prostate extracted from a 3D planning image of the patient to a boundary of the segmented prostate in the 3D ultrasound image, resulting in a fused 3D biomechanical prostate model;in response to movement of an ultrasound probe to a new location, receiving a current 2D ultrasound image acquired by the ultrasound probe at the new location; anddeforming the fused 3D biomechanical prostate model based on the current 2D ultrasound image to match a current deformation of the prostate due to the movement of the ultrasound probe to the new location.2. The method of claim 1 , further comprising:fusing the reference patient-specific biomechanical model of the prostate to a boundary of the deformed fused 3D biomechanical prostate model, resulting in a new fused 3D biomechanical prostate model.3. The method of claim 2 , further comprising:mapping locations of suspicious regions annotated in the new fused 3D biomechanical prostate model to the current 2D ultrasound image; anddisplaying the current 2D ultrasound image with the ...

System and method for acquiring optoacoustic data and producing parametric maps thereof

A method is disclosed for generating sinograms by sampling a plurality of transducers acoustically coupled with the surface of a volume of tissue over a period of time after a light pulse at one wavelength, and after another light pulse at a different wavelength, and for processing those sinograms, reconstructing at least two optoacoustic images from the two sinograms, processing the two optoacoustic images to generate two envelope images and generating a parametric map from information in the two envelope images. In an embodiment, motion and tracking are determined to align the envelope images. In an embodiment, at least a second parametric map is produced from information in the same two envelope images. In an embodiment an ultrasound image is also acquired, and the parametric map is coregistered with and overlayed upon the ultrasound image, and then displayed.

SYSTEM AND METHOD FOR PROVIDING SELECTIVE CHANNEL SENSITIVITY IN AN OPTOACOUSTIC IMAGING SYSTEM

A method for controlling an optoacoustic imaging system includes the steps of analyzing sinogram data values to identify variations, storing information concerning the variations, generating first and second sinograms, and processing the sinograms to mitigate the effect of the variations. In the analyzing step, sinogram data values are analyzed to identify one or more variations that are related to performance of one or more of the discrete components of the optoacoustic imaging system. The identified variations are then stored. A first sinogram is generated by sampling transducer elements acoustically coupled with a surface of a volume for a predetermined period of time after delivery of a pulse of light having a first wavelength, the first sinogram containing one channel for each of the transducer elements. A second sinogram is generated by sampling the transducer elements acoustically coupled with the surface of the volume for the predetermined period of time after delivery of a pulse of light having a second wavelength, the second sinogram containing one channel for each of transducer elements. The first and second sinograms are processed using the stored information to mitigate the effect of the identified variations on the respective sinogram. 1. A method for controlling an optoacoustic imaging system comprising discrete components to produce at least one optoacoustic image corrected for variations in discrete components , comprising:analyzing sinogram data values to identify one or more variations that are related to performance of one or more of the discrete components of the optoacoustic imaging system;storing information concerning the one or more identified variations;generating a first sinogram by sampling a plurality of transducer elements acoustically coupled with a surface of a volume for a predetermined period of time after a pulse of light having a first wavelength, the first sinogram containing one channel for each of the plurality of transducer ...

IONIZING RADIATION DETECTOR FOR USE WITH ENDOSCOPIC ULTRASOUND

Embodiments provided herein relate to ionizing radiation detectors for use with endoscopic ultrasounds. In some embodiments, an apparatus is provided and includes an ultrasound transducer and an ionizing radiation detector, such as a scintillating detector. The ionizing radiation detector can comprise a scintillating material and a photodetector. 1. An endoscopic ultrasound apparatus for examination of tissue , the apparatus comprising:an ultrasound transducer; andan ionizing radiation detector positioned proximally to the ultrasound transducer.2. The apparatus of claim 1 , wherein the ionizing radiation detector comprises a scintillating detector that comprises a light detector and a scintillating material.3. The apparatus of claim 2 , wherein the light detector is integrally formed with the scintillating material.4. The apparatus of claim 2 , wherein the light detector is spaced apart from the scintillating material.5. The apparatus of claim 2 , wherein the scintillating material comprises a polymer.6. The apparatus of claim 5 , wherein the polymer comprises a compound comprising an aromatic group.7. The apparatus of claim 5 , wherein the scintillating material comprises at least one fluorophore.8. The apparatus of claim 5 , wherein the polymer comprises one or more of a polystyrene claim 5 , a polyvinyltoluene claim 5 , a phenyl silicone claim 5 , an epoxy with naphthalene claim 5 , or an acrylic with naphthalene.9. The apparatus of claim 1 , wherein a distance between the ultrasound transducer and the ionizing radiation detector is 0 cm to about 1.5 cmfixed.10. (canceled)11. The apparatus of claim 1 , wherein the ionizing radiation detector comprises a detector array.12. (canceled)13. The apparatus of claim 1 , wherein the ionizing radiation detector comprises a three-dimensional shape.14. The apparatus of claim 13 , wherein the three-dimensional shape is approximately hemispherical claim 13 , approximately spherical claim 13 , or multifaceted.15. The apparatus ...

Catheter with ultrasound sensor and method for creating a volume graphic by means of the catheter

A method is provided for creating a volume graphic via a catheter for introduction into a vessel which has an ultrasound unit, which is embodied to transmit ultrasound, to measure an echo of the transmitted ultrasound, and to create image data for a two-dimensional cross-section of the vessel on the basis of the measured echo. The method involves creating image data of a cross-section with the ultrasound unit at a plurality of different positions on a movement track of the catheter, and, in addition to the image data, creating position data for the current position of the ultrasound unit with a localization device. The method further involves creating the volume graphic from the image data of all cross-sections in which the cross-sections are arranged relative to one another in accordance with the position data.

Optoacoustic-Ultrasonic Contrast Agents with Enhanced Efficiency

Provided herein are dual contrast agents or nanocomposite particles designed to enhance optoacoustic-ultrasonic imaging. The contrast agents or particles have a core designed to enhance response to incident transient ultrasonic pressure waves and at least two layers disposed around the core. The inner first layer is designed to effectively absorb incident transient optical waves, convert absorbed optical energy into heat and demonstrates significant thermal expansion and/or conversion of thermal energy into acoustic pressure. The outer second layer thermally insulates the inner layer from the surrounding aqueous environment and enhances the generation of transient ultrasonic pressure waves during optoacoustic-ultrasonic imaging and sensing. Also provided are methods of enhancing contrast in a tissue optoacoustic-ultrasonic imaging and producing enhanced optoacoustic images by contacting the tissue with the dual contrast agent or nanocomposite particles. 1. A dual contrast agent designed to enhance optoacoustic-ultrasonic imaging , comprising:a nanocomposite particle having a core effective to enhance response to incident transient ultrasonic pressure waves and at least two layers disposed around the core, said two layers comprising:a first inner layer comprising at least one compound effective to absorb incident transient optical energy, convert absorbed optical energy into heat, wherein said compound significantly thermally expands or converts thermal energy into acoustic pressure or both; anda second thermally insulating outer layer comprising at least one compound effective to insulate the inner layer from a surrounding aqueous environment, wherein the design of the nanocomposite particle enhances generation of transient ultrasonic pressure waves during optoacoustic-ultrasonic imaging.2. The dual contrast agent of claim 1 , wherein the nanocomposite particle comprises at least two layers claim 1 , the contrast agent further comprising a thin bonding layer ...

INTERFRAME ENERGY NORMALIZATION IN AN OPTOACOUSTIC IMAGING SYSTEM

An optoacoustic imaging system includes a handheld probe and first and second pulsed light sources having a common output. The first and second light sources generate pulses of light at first and second predominant wavelengths, respectively. The handheld probe includes an ultrasound transducer array having an active end located at the distal end of the handheld probe for receiving an optoacoustic return signal. A sensor measures a portion of the light transmitted along the light path. A data acquisition samples the ultrasound transducer array during a predetermined period of time after a pulse of light from the first light source and during a predetermined period of time after a pulse of light from the second light source. The sampled data is stored. An image processing unit reconstructs a first optoacoustic image based on the sampled data corresponding to a pulse of light from the first light source and reconstructs a second optoacoustic image based on the sampled data corresponding to a pulse of light from the second light source. An energy normalizing unit computes a normalization factor based on a measurement from each sensor in the array and applies the normalization factor to data corresponding to the pulse of light. 1. An optoacoustic imaging system comprising:first and second light source having a common output, the first and second light source capable of generating at least one pulse of light at a first and second predominant wavelength, respectively; ultrasound transducer array having an active end located at the distal end of the handheld probe, the array capable of receiving an optoacoustic return signal;', 'optical window located at the distal end of the handheld probe;, 'handheld probe having a distal end and a proximal end, the probe comprisinglight path adapted to direct light from the common output to the optical window of the handheld probe;at least one sensor adapted to measure a portion of the light transmitted along the light path;data ...

APPARATUS AND METHOD FOR REAL-TIME TRACKING OF TISSUE STRUCTURES

A method and system are disclosed for radiosurgical treatment of moving tissues of the heart, including acquiring at least one volume of the tissue and acquiring at least one ultrasound data set, image or volume of the tissue using an ultrasound transducer disposed at a position. A similarity measure is computed between the ultrasound image or volume and the acquired volume or a simulated ultrasound data set, image or volume. A robot is configured in response to the similarity measure and the position of the transducer, and a radiation beam is fired from the configured robot. 1. An ultrasound tissue imaging method comprising:imaging a target with an ultrasound transducer to generate a stream of ultrasound data of the target, wherein the target is included within or adjacent to an anatomical site;imaging the anatomical site with a second imaging modality to generate ultrasound correction data of the anatomical site;compensating for distortion in the stream of ultrasound data using the ultrasound correction data of the anatomical site so as to generate compensated data; andtransmitting the compensated data.2. The method of claim 1 , wherein the second imaging modality generates intermittent ultrasound correction data of the anatomical site less frequently than the ultrasound transducer; and wherein the second imaging modality comprises a bi-plane x-ray imaging modality.3. (canceled)4. The method of claim 1 , wherein compensating for distortion in the stream of ultrasound data comprises observing a time sequence of positions of the target or a surrogate of the target using the second imaging modality; and wherein the step of compensating for distortion in the stream of ultrasound data further comprises developing a first motion curve of the target position from the stream of ultrasound image data and a second motion curve of the target position from the second imaging modality data.5. (canceled)6. The method of claim 4 , wherein the step of compensating for distortion ...

ULTRASOUND DIAGNOSTIC APPARATUS AND OPERATION METHOD OF ULTRASOUND DIAGNOSTIC APPARATUS

In an ultrasound diagnostic apparatus and an operation method of the ultrasound diagnostic apparatus of the invention, a control circuit performs polarization processing on a plurality of ultrasound transducers in a non-diagnosis period, during which transmission of ultrasound waves and reception of reflected waves for performing ultrasound diagnosis are not performed, in a case where the cumulative driving time of the plurality of ultrasound transducers for performing the ultrasound diagnosis becomes equal to or longer than a specified time. A transmission circuit generates a first transmission signal having a driving voltage for performing ultrasound diagnosis using a pulse generation circuit in the case of performing the ultrasound diagnosis, and generates a second transmission signal having a polarization voltage for performing polarization processing using the same pulse generation circuit as in the case of generating the first transmission signal in the case of performing the polarization processing. 1. An ultrasound diagnostic apparatus acquiring an ultrasound image and an endoscope image , comprising:an ultrasound endoscope comprising an ultrasound observation portion that transmits ultrasound waves using an ultrasound transducer array in which a plurality of ultrasound transducers are arranged, receives reflected waves of the ultrasound waves, and outputs a reception signal; andan ultrasound processor apparatus that generates the ultrasound image by converting the reception signal into an image,wherein the ultrasound processor apparatus comprises:a control circuit that performs polarization processing on the plurality of ultrasound transducers in a non-diagnosis period, during which transmission of the ultrasound waves and reception of the reflected waves for performing ultrasound diagnosis are not performed, in a case where a cumulative driving time of the plurality of ultrasound transducers for performing the ultrasound diagnosis becomes equal to or ...

METHOD AND SYSTEM FOR IMAGE PROCESSING TO DETERMINE BLOOD FLOW

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. 1184-. (canceled)185. A method for processing images to determine cardiovascular information , comprising the steps of:receiving image data including a plurality of coronary arteries originating from an aorta;processing the image data to generate three-dimensional shape models of the coronary arteries;simulating a blood flow for the generated three-dimensional shape models of the coronary arteries; anddetermining a fractional flow reserve (FFR) of the coronary arteries based on a blood flow simulation result, wherein in the step of simulating the blood flow, a computational fluid dynamics model is applied to the three-dimensional shape models of the coronary arteries, a lumped parameter model is combined with the computational fluid dynamics model, and a simplified coronary artery circulation model including coronary arteries, capillaries of the coronary arteries and coronary veins is used as the lumped parameter model.186. The method of claim 185 , wherein claim 185 , when simulating the blood flow claim 185 , when applying the computational fluid dynamics model to the three-dimensional shape models of the coronary arteries claim 185 , using an aorta blood pressure pattern as an inlet boundary condition.187. The method of claim 185 , wherein simulating the blood flow comprises determining lengths of centerlines of the three- ...

COMPUTATIONAL FLOW DYNAMICS BASED METHOD FOR STIMATING THROMBOEMBOLIC RISK IN PATIENTS WITH MYOCARDIAL INFARCTION

The present invention provides a method for determining thromboembolic risk in a patient. The method includes processing functional images of a patient's heart in order to create a computational fluid dynamic (CFD) modeling of the patient's heart. Once a CFD model is obtained, various metrics can be determined to estimate the patient's risk of left ventricular thrombosis. This method is particularly suited for determining thromboembolic risk in patients having suffered a myocardial infarction. However, the method can also be applied to a broader population at risk of cardioembolic and cryptogenic stroke. 1. A method for estimating thromboembolic risk in a patient comprising:obtaining a functional image of a heart of the patient;constructing a patient specific model using the image data obtained from the functional image of the heart of the patient;modeling computational fluid dynamics (CFD) of the heart of the patient using the patient specific model to obtain fluid dynamics data from the image data;validating the fluid dynamics data against data obtained from an echocardiogram of the heart of the patient;calculating thrombogenic metrics from the fluid dynamics data; andgenerating a thrombogenic risk assessment using the metrics.2. The method of further comprising obtaining the functional image using at least one of a computed tomography (CT) scanner claim 1 , cardiovascular magnetic resonance imager claim 1 , echocardiography claim 1 , and radionuclide imaging.3. The method of further comprising:segmenting the functional image of the heart of the patient to obtain the patient specific model of a left ventricle of the heart;registering a template of a generic left ventricle to the model of the left ventricle of the patient; andsimulating left ventricle flow for the model of the left ventricle.4. The method of further comprising segmenting the left ventricle model into approximately 20 or more individual phases over one cardiac cycle.5. The method of further ...

INTRAORAL SCANNING USING ULTRASOUND AND OPTICAL SCAN DATA

A first multitude of intraoral images of a first portion of a three-dimensional intraoral object are received. A pre-existing model that corresponds to the three-dimensional intraoral object is identified. A first intraoral image of the first multitude of intraoral images is registered to a first portion of the pre-existing model. A second intraoral image of the first multitude of intraoral images is registered to a second portion of the pre-existing model. 1. A method comprising:receiving, by a processing device, a first plurality of intraoral images of a first portion of a three-dimensional intraoral object;identifying a pre-existing model that corresponds to the three-dimensional intraoral object;registering a first intraoral image of the first plurality of intraoral images to a first portion of the pre-existing model; andregistering a second intraoral image of the first plurality of intraoral images to a second portion of the pre-existing model.2. The method of claim 1 , further comprising:generating a virtual model of the three-dimensional intraoral object based on the registration of the first intraoral image and the second intraoral image to the pre-existing model.3. The method of claim 1 , wherein: determining first rotations and translations based on the registering the first intraoral image to the first portion of the pre-existing model; and', 'registering the second intraoral image of the first plurality of intraoral images using the second portion of the pre-existing model comprises:', 'determining second rotations and translations based on the registering the second intraoral image to the second portion of the pre-existing model., 'registering the first intraoral image of the first plurality of intraoral images using the first portion of the pre-existing model comprises4. The method of claim 3 , further comprising:applying the first rotations and translations associated with the first intraoral image to a third intraoral image of a second plurality of ...

PROVIDING A PROJECTION DATA SET

The present invention relates to providing a projection data for providing a guidance image. In order to provide an enhanced guiding image technique for generating a guidance image of the patient's anatomy to be projected on the body surface of the patient, such that a at least a basis for a corrected guidance image for a better correlation to the patient's current motion can be provided, in particular to the patient's current breathing motion state, a device () for providing a projection data set is provided that comprises a storage means (), an input interface (), a processing unit () and an output interface (). The storage means is configured to store a pre-determined basis data set representing a 3D tomographic image of a subject (). The input interface is configured to receive reference data representing a current spatial depiction at least of a target region () of the subject. The processing unit is configured to register the reference data on the pre-determined basis data set. The processing unit is further configured to transform, based on the reference data and the result of the registration, the pre-determined basis data set resulting in a working data set representing a transformed 3D tomographic image indicating the current spatial anatomy relation at least for the target region of the subject. The processing unit is also configured to segment the working data set resulting in a projection data set representing the target region of the subject. Still further, output interface is configured to provide the projection data set for a further purpose. 1. A device for providing a projection data set , comprising:a storage means;an input interface;a processing unit; andan output interface;wherein the storage means is configured to store a pre-determined basis data set representing a 3D tomographic image of a subject;wherein the input interface is configured to receive reference data representing a current spatial depiction at least of a target region of the ...

SERIAL ARCHITECTURE AND ENERGY SAVING METHODS FOR ULTRASOUND AND THERMOACOUSTIC SYSTEMS

Disclosed is the electronic architecture, including component arrangement and use of switches, and power saving method for use in a dual mode USTA instrumentation. In an embodiment, the instrument architecture includes US and TA analog components, including a transducer, TA preamplifier, pulser, switches, and AFE (or ADC with programmable amplifier) arranged in a way which allows efficient usage of the same transducer elements, electronic components, wiring, and AFE channels in both US and TA modalities. The operation with fast power control over the TA preamplifier is described, which allows turning off the TA preamplifier power between TA measurements cycles with or without US measurement between TA measurements. TA preamplifier energy saving allows such designs to reduce TA preamplifier power consumption many times, which enables TA preamplifier integration inside transducer housing or probe housing, and/or the use of the TA preamplifier in portable battery-operated or hand-held devices. 1. An instrument for thermoacoustic data acquisition and/or imaging , comprising:a transducer or a transducer array for receiving thermoacoustic signals from an interrogated object;a thermoacoustic data acquisition unit comprising a thermoacoustic preamplifier and an analog front end for providing analog to digital conversion of input signals, said data acquisition unit or one or more of its individual components having a fast-disable low power mode and a fast-enable full power mode, each mode being capable of being activated multiple times per second between and during measurement cycles;wherein the thermoacoustic data acquisition unit is configured to amplify and digitize signals received by said transducer or said transducer array;a circuit providing digital processing and/or digital control in the instrument;wherein the instrument is configured to switch said thermoacoustic data acquisition unit or one or more of its components between low power mode and full power mode ...

Visualization and recordation system interface with virtual ground for biomedical system and methods

Methods, apparatus, and systems for medical procedures are disclosed herein. For example, a plurality of analog sensor signals and an analog reference signal are received by an analog-to-digital converter to produce respective digitized versions of the analog sensor signals. The respective digitized versions of the analog sensor signals are digital filtered to produce respective filtered digitized versions of the analog sensor signals. The filtered digitized versions of the analog sensor signals are output to a visualization system to provide real time display thereof. The filtered digitized versions of the analog sensor signals are communicated to a digital-to-analog converter to produce an analog version of the filtered digitized versions of the analog sensor signals. The analog version of the filtered digitized versions of the analog sensor signals along with the analog reference signal are output to a recordation system to provide supplemental processing and storage thereof.

Devices, Systems, and Methods for Improved Accuracy Model of Vessel Anatomy

Devices, systems, and methods of imaging a blood vessel are provided. For example, the method can include obtaining fluoroscopic image data of a region of interest in a blood vessel using an x-ray source; obtaining intravascular ultrasound (IVUS) data at a plurality of positions across the region of interest using an IVUS component disposed on an intravascular device; processing the fluoroscopic image data and IVUS data, including: determining, using the fluoroscopic image data, a position of the intravascular device with respect to the x-ray source at each of the plurality of positions across the region of interest; co-registering the fluoroscopic image data and the IVUS image data; and generating, a model of the region of interest including position information of a border of a lumen of the blood vessel at each of the plurality of locations; and outputting a visual representation of the model of the region of interest.

SEGMENTATION OF LARGE OBJECTS FROM MULTIPLE THREE-DIMENSIONAL VIEWS

The present invention relates to an ultrasound imaging system () for inspecting an object () in a volume (). The ultra-sound imaging system comprises an ultrasound image acquisition probe () for acquiring three-dimensional ultrasound images and providing three-dimensional ultrasound image data, comprising a tracking device () for tracking a position of the ultrasound image acquisition probe () and providing a viewpoint position () of the three-dimensional ultrasound images. By this, an improved initialization and improved co-registration and co-segmentation is enabled by providing a plurality of three-dimensional ultrasound images and their respective viewpoint positions (), and to conduct a segmentation () of the object () simultaneously out of the plurality of three-dimensional ultrasound images and taking into account the viewpoint positions (). 1. An ultrasound imaging system for inspecting an object in a volume , the ultrasound imaging system comprising:an ultrasound image acquisition probe for acquiring three-dimensional ultrasound images and providing three-dimensional ultrasound image data, comprising a tracking device for tracking a position of the ultrasound image acquisition probe and providing a viewpoint position of the three-dimensional ultrasound images, andan image processor configured to receive the three-dimensional ultrasound image data and to provide display data, wherein the image processor is configured to receive a plurality of three-dimensional ultrasound images and their respective viewpoint positions, and to conduct a segmentation of the object simultaneously out of the plurality of three-dimensional ultrasound images.2. The ultrasound imaging system of claim 1 , wherein the image processor is configured to conduct the segmentation by minimizing an energy term so that a deformed initial geometric shape matches the object's boundary as good as possible.3. The ultrasound imaging system of claim 2 , wherein the energy term comprises a first ...

SENSOR COORDINATE CALIBRATION IN AN ULTRASOUND SYSTEM

Sensor coupled to the ultrasound probe provides position information related to an ultrasound imaging position in the object. A processor performs first registration between the medical image and the ultrasound image based on the anatomical feature in the ultrasound image and a medical image of the object acquired by imaging modality different from the ultrasound apparatus, obtains first registration information which provides a relationship between a coordinate system of the medical image and a coordinate system of the ultrasound image based on the first registration, performs second registration between the sensor and the medical image based on the position information and the first registration information, and obtains second registration information based on the second registration. A display may display a portion of the medical image corresponding to the ultrasound imaging position based on the second registration information. 1. A medical imaging apparatus comprising:an ultrasound apparatus including an ultrasound probe configured to transmit and receive an ultrasound signal to obtain an ultrasound image of an object;a sensor coupled to the ultrasound probe and configured to provide a position information related to an ultrasound imaging position in the object; anda processor configured to extract a certain anatomical feature from the ultrasound image and the certain anatomical feature from a medical image of the object acquired by an imaging modality different from the ultrasound apparatus, perform a first registration between the medical image and the ultrasound image based on the certain anatomical feature, obtain a first registration information which provides a relationship between a coordinate system of the medical image and a coordinate system of the ultrasound image based on the first registration, perform a second registration between the sensor and the medical image based on the position information and the first registration information, obtain a ...

METHOD AND APPARATUS FOR DETERMINING LOCAL ACOUSTIC FIELD INTENSITY WITHIN A SOFT SOLID

This method, for determining the local intensity (I) of an acoustic field propagating in a target region of a soft solid, at a position located within said target region, includes at least the following steps: determining () a value of an ultrasound attenuation coefficient (α) of the soft body in the target region; determining () a value of the shear modulus (μ) of the soft body in the target region; determining () a value of the speed of sound (c) in the target region of the soft body; and building (), with the values determined in steps a), b) and c), a viscoelastic model (M) of a steady-state displacement induced by an acoustic field having a time invariant shape or a viscoelastic model of a difference between two steady-state displacements induced by an acoustic field having a time invariant shape. Moreover, this method also includes the following steps: applying () to the target region the acoustic field emitted by an ultrasound source, for a duration such that the acoustic field induces a steady-state localized deformation (Formula (I)) of the soft body in the target region; measuring () at least one steady state displacement induced by the acoustic field at a given position in the target region; and computing () the amplitude of the intensity of the acoustic field at said given position by inverting the viscoelastic model (M) at said given position, for the displacement(s) measured at step f). 12828. Method for determining a local intensity (I) of an acoustic field (AF) induced by an ultrasound source () and propagating in a target region () of a soft solid () , at a position ({right arrow over (r)}) located within said target region , characterized in that said method includes at least the following steps:{'b': '102', 'a) determining () a value of an ultrasound attenuation coefficient (α) of the soft body in the target region;'}{'b': '104', 'b) determining () a value of the shear modulus (μ) of the soft body in the target region;'}{'b': '106', 'c) ...

ACOUSTIC WAVE IMAGE DISPLAY DEVICE AND METHOD

A first acoustic wave image and a second acoustic wave image are displayed on top of each other in different display colors, and a first operation icon for selecting the first acoustic wave image and a second operation icon for selecting the second acoustic wave image are displayed on operation icon display unit. The first operation icon and the second operation icon are displayed on top of each other in a display order identical to a display order of the first acoustic wave image and the second acoustic wave image that are displayed on top of each other on image display unit. 1. An acoustic wave image display device in a system for displaying a first acoustic wave image and a second acoustic wave image on image display unit , the first acoustic wave image being generated on the basis of detected signals of photoacoustic waves generated , from within a subject , by the subject receiving light emitted to the subject , the second acoustic wave image being generated on the basis of detected signals of reflected acoustic waves , which are acoustic waves transmitted to the subject and reflected within the subject , the acoustic wave image display device comprising:an image display control unit that causes the first acoustic wave image and the second acoustic wave image to be displayed on top of each other on the image display unit in different display colors;operation icon display unit for displaying a first operation icon for selecting the first acoustic wave image and a second operation icon for selecting the second acoustic wave image; andan operation icon display control unit that causes the first operation icon and the second operation icon to be displayed on top of each other on the operation icon display unit in a display order identical to a display order of the first acoustic wave image and the second acoustic wave image that are displayed on top of each other on the image display unit.2. The acoustic wave image display device according to claim 1 , further ...

MEDICAL IMAGING APPARATUS AND METHOD OF OPERATING SAME

Provided is a method of operating a medical imaging apparatus, comprising: acquiring a first image of a first type corresponding to a first respiratory state of an object; determining motion information of the object with respect to a respiratory state, based on first and second images of a second type respectively corresponding to the first respiratory state and a second respiratory state of the object; and generating a second image of the first type corresponding to the second respiratory state by applying the motion information to the first image of the first type. 1. A method of operating a medical imaging apparatus , the method comprising:acquiring a first image of a first type corresponding to a first respiratory state of an object;determining motion information of the object with respect to a respiratory state, based on first and second images of a second type respectively corresponding to the first respiratory state and a second respiratory state of the object; andgenerating a second image of the first type corresponding to the second respiratory state by applying the motion information to the first image of the first type.2. The method of claim 1 , further comprising matching at least one of the first and second images of the first type with at least one of the first and second images of the second type.3. The method of claim 2 , wherein the matching of the at least one of the first and second images of the first type with the at least one of the first and second images of the second type comprises matching at least two images of the first and second types corresponding to a same respiratory state.4. The method of claim 2 , further comprising displaying a matched image.5. The method of claim 1 , further comprising:displaying at least one of the first and second images of the first type and at least one of the first and second images of the second type; andreceiving a user input for selecting the at least one of the first and second images of the first type ...

UPDATING AN INDICATION OF A LUMEN LOCATION

Apparatus and methods are described including an endoluminal device configured to move along a portion of a lumen of a subject's body, an extraluminal imaging device, and at least one computer processor. While the endoluminal device moves along the portion of the lumen, a display displays an extraluminal image of the lumen in which a first indication of a location of the lumen is shown. The extraluminal imaging device acquires a sequence of extraluminal images of the endoluminal device moving along the portion of the lumen. The indication of the location of the lumen that is displayed is updated based upon the acquired sequence of extraluminal images, and the acquired sequence of images is displayed with the updated indication of the location of the lumen overlaid upon the images. Other applications are also described. 1. An apparatus , comprising: drive the display to display an extraluminal roadmap image of a lumen of a body of a subject, the extraluminal roadmap image showing a pathway of the lumen, wherein the extraluminal roadmap image is obtained with a contrast agent within the lumen;', 'identify, in the extraluminal roadmap image, a plurality of first pixels comprising the pathway of the lumen;', 'acquire, using the extraluminal imaging device, a plurality of extraluminal images of an endoluminal device moving along the lumen, wherein the plurality of extraluminal images is obtained without the contrast agent within the lumen;', 'select a master image comprising a plurality of second pixels, wherein the master image comprises a first extraluminal image in the plurality of extraluminal images or a blank image with a size corresponding to a size of the first extraluminal image;', 'determine a closest pixel of the plurality of second pixels to a pixel of the plurality of first pixels;', 'determine a distance between the closest pixel of the plurality of second pixels and the pixel of the plurality of first pixels;', 'identify, in a second extraluminal image of ...

Dual modality imaging system for coregistered functional and anatomical mapping

A real-time imaging system that provides ultrasonic imaging and optoacoustic imaging coregistered through application of the same hand-held probe to generate and detect ultrasonic and optoacoustic signals. These signals are digitized, processed and used to reconstruct anatomical maps superimposed with maps of two functional parameters of blood hemoglobin index and blood oxygenation index. The blood hemoglobin index represents blood hemoglobin concentration changes in the areas of diagnostic interest relative to the background blood concentration. The blood oxygenation index represents blood oxygenation changes in the areas of diagnostic interest relative to the background level of blood oxygenation. These coregistered maps can be used to noninvasively differentiate malignant tumors from benign lumps and cysts.

IMAGING APPARATUS FOR DIAGNOSIS, CONTROL METHOD THEREFOR, PROGRAM, AND COMPUTER READABLE STORAGE MEDIUM

A control method, computer readable medium, and imaging apparatus for diagnosis being configured to create a tomographic image are disclosed. The method includes obtaining ultrasound line data oriented in a radial direction from a rotation center based on a signal obtained by executing the scanning; obtaining optical interference line data oriented in a radial direction from the rotation center based on a signal obtained by executing the scanning; identifying a line or a group of lines having a same feature out of each line data of the ultrasound tomographic image and the optical tomographic image; determining segmentation positions for a bundle of lines corresponding to at least a single frame included in each tomographic image from each line data of the ultrasound tomographic image and the optical tomographic image with respect to the identified line or group of lines; and creating a tomographic image from the determined bundle of lines. 1. A control method of an imaging apparatus for diagnosis , the imaging apparatus for diagnosis being configured to create an ultrasound tomographic image and an optical tomographic image inside an examination target object to which an imaging core moves using a probe that houses the imaging core provided with an ultrasound transceiver and an optical transceiver by performing scanning moves the imaging core along an axial direction of the probe while rotating the imaging core , the control method comprising:obtaining ultrasound line data oriented in a radial direction from a rotation center on a basis of a signal obtained by executing the scanning;obtaining optical interference line data oriented in a radial direction from the rotation center on a basis of a signal obtained by executing the scanning;identifying a line or a group of lines having a same feature out of each line data of the ultrasound tomographic image and the optical tomographic image;determining segmentation positions for a bundle of lines corresponding to at least ...

Three-dimensional model for surgical planning

Pre-surgical planning can use a three-dimensional model of an anatomical structure having a plurality of fiduciary points and a surgical mark integrated into the three-dimensional model using a contrast material. A model image of the three-dimensional model can be superimposed with a diagnostic image of the anatomical structure using the plurality of fiduciary points in order to create a superimposed image.

Method and Apparatus for Registering Image Data Between Different Types of Image Data to Guide a Medical Procedure

A method and apparatus are provided for registering image data between two different types of image data. The image data is obtained during two separate scanning processes. The first process is a high-resolution imaging process, such as a CT scan or an MRI. The second process is a lower resolution process, such as ultrasound. The image data is registered in real time so that the combined image data can be displayed during the second process to guide a medical professional during a procedure. 1. A method for registering image data between two images , comprising the steps of:scanning a patient using a first imaging modality to obtain a first set of image data for a portion of the patient;scanning a patient using a second imaging modality to obtain a second set of image data for the portion of the patient;identifying a portion of the first set of image data corresponding to a portion of interest; andanalyzing the second set of data relative to the identified portion to identify a portion of the second image data corresponding to the portion of interest.2. The method of comprising the step of illustrating the portion of interest on a display of the second image data in response to the step of analyzing the second set of image data.3. A method for registering image data of a patient from two imaging devices to guide a surgical procedure claim 1 , wherein a first set of image data of the patient is provided by a first imaging device using a first imaging modality claim 1 , wherein the method comprises the steps of:scanning a patient using a second imaging device to obtain a second set of image data for a portion of the patient, wherein the second imaging device uses a second imaging modality that is different than the first imaging modality;automatically processing the second set of image data to correlate the second set of image data with the first image data modality to align image data of a target tissue of the patient from the second imaging modality with image data ...

Quantitative Imaging System and Uses Thereof

Provided herein are imaging systems such as a system for quantitative tomography and a laser optoacoustic ultrasonic imaging system assembly (LOUISA) for imaging a tissue region, for example, a breast, in a subject. Generally, the system components are a laser that emits instant pulses of laser light in a wavelength cycling mode, fiberoptic bundles or optical arc-shaped fiber bundles configured to deliver laser light, an imaging module with an imaging tank, an optoacoustic array(s) of ultrawide-band ultrasonic transducers and ultrasound array(s) of ultrasonic transducers and a coupling medium and an electronics subsystem. Also provided is a method for imaging quantitative functional parameters and/or molecular parameters and anatomical structures in a volumetric tissue region of interest, such as a breast, in a subject utilizing the system for quantitative tomography.

IMAGING APPARATUS FOR DIAGNOSIS AND PROGRAM

An imaging apparatus is disclosed for diagnosis generating a first tomographic image and a second tomographic image inside a lumen of a measurement subject body by using an ultrasound signal which is transmitted and received by a first transmitting and receiving unit and an optical signal which is transmitted and received by a second transmitting and receiving unit in a case where a transmitting and receiving unit in which the first transmitting and receiving unit performing transmission and reception of the ultrasound signal and the second transmitting and receiving unit performing transmission and reception of the optical signal are disposed moves in an axial direction while rotating in the lumen of the measurement subject body. 1. An imaging apparatus for diagnosis generating a first tomographic image and a second tomographic image inside a lumen of a measurement subject body by using an ultrasound signal which is transmitted and received by a first transmitting and receiving unit and an optical signal which is transmitted and received by a second transmitting and receiving unit in a case where a transmitting and receiving unit in which the first transmitting and receiving unit performing transmission and reception of the ultrasound signal and the second transmitting and receiving unit performing transmission and reception of the optical signal are disposed moves in an axial direction while rotating in the lumen of the measurement subject body , the apparatus comprising:first discrimination means for discriminating whether to generate both the first tomographic image and the second tomographic image or to generate only the first tomographic image; andgain correction means for changing a gain at a time of generating the first tomographic image based on the ultrasound signal received by the first transmitting and receiving unit, in accordance with a result of discrimination made by the first discrimination means.2. The imaging apparatus for diagnosis according to ...

Method, device, and system for determining abnormality in myocardium region

A method, device, and system for determining at least one blood vessel contributing to an abnormality in a myocardium region are provided. The method includes receiving from a medical imaging device a medical image associated with the myocardium region. The method further includes identifying from the medical image a region of abnormality in the myocardium region. Additionally, the method includes generating a simulation of a plurality of blood vessels associated with the myocardium region. The method includes determining from the simulation of the plurality of blood vessels at least one blood vessel contributing to the abnormality in the myocardium region. The at least one blood vessel is associated with the region of abnormality in the myocardium region.

ULTRASOUND GUIDANCE SYSTEM AND METHOD

An ultrasound guidance system and method include an augmented reality device, a camera, and a computing system. The computing system receives a user input from a user including a target internal anatomical structure of the patient. The computing system then processes image data of surface anatomy of the patient captured by the camera. The computing system processes the image data to identify surface anatomical structures to locate underlying internal anatomy of the patient. The computing system uses this information to determine a probe location on a surface of the patient in which an ultrasound probe is capable of imaging the target internal anatomical structure of the patient when placed against the surface. The computing system then generates output data for a display of the augmented reality device including a target indicia that overlays an image of the patient on the display at the probe location. 1. A guidance system comprising:an augmented reality device having a display;a camera configured to capture image data; and receive a user input from a user, the user input comprising a target internal anatomical structure of the patient,', 'process the image data captured by the camera, the image data comprising at least an image of surface anatomy of the patient, wherein processing the image data comprises identifying at least one surface anatomical structure of the patient to locate internal anatomy of the patient,', 'determine a probe location, based on the processed image data and the user input, wherein the probe location is on a surface of the patient where an ultrasound probe, when placed against the surface at the location, is capable of imaging the target internal anatomical structure of the patient, and', 'generate output data for the display of the augmented reality device, the output data comprising a target indicia, wherein the target indicia overlays an image of the patient, on the display, at the probe location., 'a computing system comprising a ...

Nonlinear Imaging with Dual Band Pulse Complexes

The invention presents methods and instrumentation for measurement or imaging of a region of an object with waves of a general nature, for example electromagnetic (EM) and elastic (EL) waves, where the material parameters for wave propagation and scattering in the object depend on the wave field strength. The invention specially addresses suppression of 3order multiple scattering noise, referred to as pulse reverberation noise, and also suppression of linear scattering components to enhanced signal components from nonlinear scattering. The pulse reverberation noise is divided into three classes where the invention specially addresses Class I and Class II 3order multiple scattering that are generated from the same three scatterers, but in opposite sequence. 1. A method for measurement or imaging of a region of an object with waves where object material parameters for wave propagation are modified by the wave field strength , comprising the steps of: a low frequency (LF) pulse with frequencies in an LF band transmitted from an LF aperture, and', 'a high frequency (HF) pulse with frequencies in an HF band transmitted from an HF aperture, —wherein the pulse length of the transmitted HF pulse is less than half an oscillation period of the transmitted LF pulse;', 'wherein the transmitted HF pulse propagates spatially so close to or within the transmitted LF pulse that the HF pulse observes a manipulation of the object material parameters by the co-propagating LF pulse for at least a part of a propagation depth of the HF pulse; and', 'wherein at least the transmitted LF pulse varies for each transmitted pulse complex to produce different manipulations of the object, and for each transmit direction at least one LF pulse is non-zero and the transmitted LF pulse can also be zero;, 'a) transmitting at least two pulse wave complexes in each of at least two transmit directions towards the region, each of said pulse complexes comprising'}b) picking up HF receive signals from one ...

MULTI-MODAL IMAGING ALIGNMENT

A controller for maintaining alignment of X-Ray imagery and ultrasound imagery includes a memory that stores instructions, and a processor that executes the instructions. When executed by the processor, the instructions cause the controller to execute a process that includes receiving data from an X-Ray system used to perform X-Ray imaging, and receiving data from an ultrasound imaging probe used to perform ultrasound imaging. The process executed by the controller also includes registering imagery based on X-Rays to imagery from the ultrasound imaging probe based on an X-Ray image of the ultrasound imaging probe among the imagery based on X-Rays, and detecting, from the data from the ultrasound imaging probe, movement of the ultrasound imaging probe. 1. A controller for maintaining alignment of X-Ray imagery and ultrasound imagery , comprising:a memory that stores instructions; anda processor that executes the instructions,wherein, when executed by the processor, the instructions cause the controller to execute a process comprising:receiving data from an X-Ray system used to perform X-Ray imaging;receiving data from an ultrasound imaging probe used to perform ultrasound imaging, registering imagery based on X-Rays to imagery from the ultrasound imaging probe based on an X-Ray image of the ultrasound imaging probe among the imagery based on X-Rays; anddetecting, from the data from the ultrasound imaging probe, movement of the ultrasound imaging probe.2. The controller of claim 1 , determining that the movement of the ultrasound imaging probe exceeds a predetermined threshold, and', 'generating a notification based on detecting the movement of the ultrasound imaging probe., 'wherein the process executed by the controller further comprises3. The controller of claim 1 , wherein the process executed by the controller further comprises:compensating for the movement of the ultrasound imaging probe to maintain alignment between the imagery based on X-Rays and the imagery ...

MEDICAL IMAGING SYSTEM, SURGICAL GUIDANCE SYSTEM AND MEDICAL IMAGING METHOD

A medical imaging system according to embodiment includes an ultrasonic probe, positioning circuitry, first mapping relationship estimation circuitry, repositioning circuitry and a display. The first mapping relationship estimation circuitry estimates a first mapping relationship between a position of the ultrasonic probe when a subject is in a first position state and a position of the ultrasonic probe when the subject is in a second position state. The repositioning circuitry determines a target position of a volume image corresponding to the position of the ultrasonic probe in the second position state according to the first mapping relationship and a second mapping relationship between the position of the ultrasonic probe in the first position state and the target position of the volume image of the subject. The display displays the image of the target position obtained from the volume image according to the target position of the volume image. 1. A medical imaging system , comprising:an ultrasonic probe configured to transmit and receive ultrasonic waves;positioning circuitry attached to the ultrasonic probe to detect a position of the ultrasonic probe;first mapping relationship estimation circuitry configured to record the position of the ultrasonic probe when a subject is in a first position state and the position of the ultrasonic probe when the subject is in a second position state and estimate a first mapping relationship between the position of the ultrasonic probe in the first position state and the position of the ultrasonic probe in the second position state;repositioning circuitry configured to determine a target position of a volume image corresponding to the position of the ultrasonic probe in the second position state according to the first mapping relationship and a second mapping relationship between the position of the ultrasonic probe in the first position state and the target position of the volume image of the subject; anda display configured ...

SYSTEM AND METHOD FOR REGISTERING ULTRASOUND INFORMATION TO AN X-RAY IMAGE

A system and a method of medical imaging includes registering an ultrasound image to a non-ultrasound image according to a first transformation. The system and method includes registering the non-ultrasound image to the x-ray image according to a second transformation. The system and method includes registering the ultrasound image to the x-ray image based on the first transformation and the second transformation and co-displaying ultrasound information registered to the x-ray image. The ultrasound information is based on the ultrasound data. 1. A method of medical imaging comprising:accessing ultrasound data;generating an ultrasound image based on the ultrasound data;accessing a non-ultrasound image and an x-ray image;registering the ultrasound image to the non-ultrasound image according to a first transformation;registering the non-ultrasound image to the x-ray image according to a second transformation;registering the ultrasound image to the x-ray image based on the first transformation and the second transformation; andco-displaying ultrasound information registered to the x-ray image,wherein the ultrasound information is based on the ultrasound data.2. The method of claim 1 , wherein the ultrasound image comprises a live ultrasound image.3. The method of claim 2 , wherein said registering the ultrasound image to the x-ray image is performed in real-time and claim 2 , wherein said co-displaying the ultrasound information registered to the x-ray image is updated in real-time.4. The method of claim 1 , further comprising identifying a location on the ultrasound image claim 1 , and wherein the ultrasound information comprises a marker indicating a corresponding location on the x-ray image.5. The method of claim 1 , wherein the ultrasound information comprises a graphic positioned on the x-ray image to indicate a region or volume from which the ultrasound data was acquired.6. The method of claim 5 , wherein the graphic comprises an outline of the region or the ...

ULTRASOUND DIAGNOSTIC APPARATUS, MEDICAL IMAGE PROCESSING APPARATUS, AND MEDICAL IMAGE PROCESSING METHOD

An ultrasound diagnostic apparatus according to one embodiment includes processing circuitry. The processing circuitry acquires local function index values related to a right ventricle. The processing circuitry generates a functional image of the right ventricle representing a distribution of the local function index values, using a medical model diagram of the right ventricle, the medical model diagram being a model diagram in which the right ventricle is developed onto a plane, and in which a blood inlet portion leading into the right ventricle and a blood outflow portion leading out from the right ventricle are plotted to positions that are separated from each other on the external circumference side of the model diagram. The processing circuitry then causes a display to display the functional image of the right ventricle. 1. An ultrasound diagnostic apparatus comprising processing circuitry configured to:acquire local function index values related to a right ventricle;generate a functional image of the right ventricle representing a distribution of the local function index values, using a medical model diagram of the right ventricle, the medical model diagram being a model diagram in which the right ventricle is developed onto a plane, and in which a blood inlet portion leading into the right ventricle and a blood outflow portion leading out from the right ventricle are plotted to positions that are separated from each other on an external circumference side of the model diagram; andcause a display to display the functional image of the right ventricle.2. The ultrasound diagnostic apparatus according to claim 1 , wherein the processing circuitry is configured to generate the functional image of the right ventricle in which the local function index values are mapped to corresponding positions of a region separating the blood inlet portion and the blood outflow portion claim 1 , in the medical model diagram of the right ventricle.3. The ultrasound diagnostic ...

ULTRASONIC IMAGE PICKUP DEVICE AND IMAGE PROCESSING DEVICE

Alignment of an ultrasonograph and volume data obtained beforehand is correctly performed without requiring a user to perform complicated operation. First volume data for an ultrasonograph and second volume data obtained by another imaging apparatus are received and aligned. A predetermined imaging part selected from a plurality of imaging parts of a subject is received from a user. The second volume data are initially rotated by a rotation angle corresponding to the imaging part received by the receptor, and alignment of the initially rotated second volume data and the first volume data after is further carried out. 1. An ultrasonic imaging apparatus comprising:an ultrasound probe that transmits a ultrasonic wave to a subject and receives a ultrasonic wave from the subject,a position sensor attached to the ultrasound probe,an image generator that generates an ultrasonograph from the signal received by the ultrasound probe, and generates first volume data from the ultrasonograph and positional information of the ultrasound probe obtained from the position sensor, andan image processor that receives and processes second volume data obtained for the subject by another external imaging apparatus, wherein:the image processor comprises an aligner that carries out alignment of the first volume data and the second volume data,the aligner comprises a receptor that receives a predetermined imaging part selected from a plurality of imaging parts of the subject from a user, and a rotation processor,the rotation processor initially rotates the second volume data by a rotation angle corresponding to the imaging part received by the receptor, and further carries out alignment of the initially rotated second volume data and the first volume data.2. The ultrasonic imaging apparatus according to claim 1 , wherein the rotation processor obtains the rotation angle corresponding to the imaging part received by the receptor from a relation of a plurality of imaging parts and rotation ...

PHOTOACOUSTIC TRACKING AND REGISTRATION IN INTERVENTIONAL ULTRASOUND

An intraoperative registration and tracking system includes an optical source configured to illuminate tissue intraoperatively with electromagnetic radiation at a substantially localized spot so as to provide a photoacoustic source at the substantially localize spot, an optical imaging system configured to form an optical image of at least a portion of the tissue and to detect and determine a position of the substantially localized spot in the optical image, an ultrasound imaging system configured to form an ultrasound image of at least a portion of the tissue and to detect and determine a position of the substantially localized spot in the ultrasound image, and a registration system configured to determine a coordinate transformation that registers the optical image with the ultrasound image based at least partially on a correspondence of the spot in the optical image with the spot in the ultrasound image. 1. An intraoperative registration and tracking system , comprising:an optical source configured to illuminate tissue intraoperatively with electromagnetic radiation at a substantially localized spot so as to provide a photoacoustic source at said substantially localize spot;an optical imaging system configured to form an optical image of at least a portion of said tissue and to detect and determine a position of said substantially localized spot in said optical image;an ultrasound imaging system configured to form an ultrasound image of at least a portion of said tissue and to detect and determine a position of said substantially localized spot in said ultrasound image; anda registration system configured to determine a coordinate transformation that registers said optical image with said ultrasound image based at least partially on a correspondence of said spot in said optical image with said spot in said ultrasound image.2. An intraoperative registration and tracking system according to claim 1 , wherein said optical source is configured to illuminate said ...

APPARATUS AND METHOD FOR REAL-TIME TRACKING OF TISSUE STRUCTURES

A method and system are disclosed for radiosurgical treatment of moving tissues of the heart, including acquiring at least one volume of the tissue and acquiring at least one ultrasound data set, image or volume of the tissue using an ultrasound transducer disposed at a position. A similarity measure is computed between the ultrasound image or volume and the acquired volume or a simulated ultrasound data set, image or volume. A robot is configured in response to the similarity measure and the position of the transducer, and a radiation beam is fired from the configured robot. 1. A system for estimating ultrasound image quality at a variety of positions to determine a desired ultrasound transducer position , the system comprising:an input module configured to receive anatomical image data from a first imaging modality, the anatomical image data including a target;an image quality estimation module coupled to the input module, the image quality estimation module configured to estimate ultrasound image quality when imaging the target at a position relative to the target by analyzing the acquired image data to estimate ultrasound velocity along a route from the position to the target, the route passing through one or more tissue types; anda display module coupled with the image quality estimation module, the display module configured to output an indication of the ultrasound image quality at positions relative to the target to the user.2. The system of claim 1 , wherein the received image data comprises CT image data claim 1 , and wherein the route is evaluated by the image quality estimation module by classifying the route tissue types based on their CT intensity values.3. The system of claim 2 , wherein the image quality estimation module virtually propagates an ultrasound beam along the route and through the one or more tissue types using a ray casting method and estimates ultrasound transmission at discrete sampling points by calculating a different between incoming ...

ELASTOGRAPHY IMAGING WITH MAGNETIC RESONANCE IMAGING GUIDED FOCUSED ULTRASOUND

A technology is described for multipoint tissue elastic property measurement. An example method (700) 700 includes generating a treatment map (710) of an anatomical region that shows focal points within the anatomical region to be exposed to Focused Ultrasound (FUS) pulses; acquiring a reference MR-ARFI image () of the anatomical region containing the focal points using the treatment map; acquiring an active MR-ARFI image () for each of the focal points in the anatomical region during exposure of the focal points to the FUS pulses using the treatment map; interleaving the reference MR-ARFI image and active MR-ARFI images () to create a combined image of the anatomical region and the focal points; and calculating a tissue displacement measurement () for the focal points exposed to the simultaneous and/or rapidly interleaved FUS pulses using the combined image of the anatomical region and the focal points exposed to the simultaneous FUS pulses. 1. A system for multipoint tissue elastic property measurement comprising:an imaging apparatus operable in conjunction with a treatment apparatus configured to acquire a reference image of an anatomical region containing focal points prior to exposing the focal points to focused ultrasound (FUS) pulses and to acquire an active image for each of the focal points in the anatomical region during exposure of the focal points to the FUS pulses; anda computing apparatus configured to interleave the reference image of the anatomical region and active images for the focal points creating a combined image of the anatomical region and the focal points, and calculate displacement measurements for the focal points exposed to the FUS pulses using the combined image.2. A system as in claim 1 , wherein the imaging apparatus comprises a Magnetic Resonance Imaging (MM) apparatus that is in communication with the computing apparatus.3. A system as in claim 1 , wherein the treatment apparatus comprises an ultrasound transducer configured to emit ...

Ultrasonic apparatus and method of controlling the same

Disclosed are an ultrasonic apparatus for displaying one of an ultrasonic image, an external image and a composite image thereof by recognizing the position of eyes of a user, and a control method thereof. The ultrasonic apparatus includes a storage configured to store an external image of an object, an image processor configured to generate a composite image by registering an ultrasonic image of the object with respect to the stored external image, a recognizer configured to recognize a position of eyes of a user, and a display configured to display one of the ultrasonic image, the external image and the composite image of the ultrasonic image and the external image, based on the recognized position of the eyes of the user.

System And Method For Mixed Modality Acoustic Sampling

Systems and methods for relaying electrical signals representing acoustic response of a volume of tissue to light and ultrasound stimulation. In an embodiment, a plurality of ultrasound transducers receive acoustic energy from the volume and generate electrical energy, which is transmitted via an electrical path to a relay system. The ultrasound transducers are operated at a wide band frequency of at least 1 MHz to 5 MHz to receive acoustic energy from the volume of tissue responsive to light stimulation and at a narrower band frequency to receive acoustic energy from the volume of tissue responsive to acoustic stimulation. The relay system relays the electrical signals to an optoacoustic system or an ultrasound instrument for further processing depending on whether the electrical signals resulted from ultrasound or light stimulation. In an embodiment, optoacoustic, ultrasound, or other images are generated from the electrical signals and may be coregistered, overlayed, or displayed. 1. A system for selectively relaying electrical signals representing an acoustic response of a volume of tissue , comprising:an optoacoustic system capable of processing electrical signals resulting from light stimulation, the optoacoustic system comprising an electrical input having a first impedance and being configured to receive electrical signals representing an acoustic response of the volume resulting from light stimulation;an ultrasound instrument capable of processing electrical signals resulting from ultrasound stimulation, the ultrasound instrument comprising an electrical input having a second impedance and being configured to receive electrical signals representing an acoustic response of the volume resulting from ultrasound stimulation; an electrical path input;', "an optoacoustic system output, the optoacoustic system output being operatively connected to the optoacoustic system's electrical input;", "an ultrasound instrument output, the ultrasound instrument output being ...

Photoacoustic Imaging Apparatus

In a photoacoustic imaging apparatus, a detecting portion includes a light source portion having a plurality of LED elements, an ultrasonic detector arranged in the vicinity of the light source portion, configured to detect an acoustic wave as an ultrasonic wave generated by absorption of light emitted from the light source portion to a test object, and a light source drive circuit arranged in the vicinity of the light source portion, driving the light source portion. 1. A photoacoustic imaging apparatus comprising:a detecting portion configured to be capable of emitting light to a test object, detecting an acoustic wave generated by absorption of the light that is emitted by a target in the test object; anda signal processing portion processing and imaging a signal detected by the detecting portion,the detecting portion arranged close to the test object, including a light source portion having a plurality of LED elements emitting the light to the test object, an ultrasonic detector arranged in a vicinity of the light source portion, configured to detect the acoustic wave as an ultrasonic wave generated by the absorption of the light emitted from the light source portion to the test object, and a light source drive circuit arranged in the vicinity of the light source portion, driving the light source portion.2. The photoacoustic imaging apparatus according to claim 1 , whereinthe ultrasonic detector has an ultrasonic vibrating element detecting the acoustic wave as the ultrasonic wave, andin a plan view, the ultrasonic vibrating element is arranged in a substantially central portion of the detecting portion, and the light source portion is arranged adjacent to the ultrasonic vibrating element.3. The photoacoustic imaging apparatus according to claim 2 , whereinthe ultrasonic vibrating element of the ultrasonic detector is arranged to extend along a first direction, andthe light source portion having the LED elements is arranged in a vicinity of the ultrasonic ...

Using ultrasound and artificial intelligence to assess muscle stretch reflexes

The present disclosure provides using ultrasound technology and artificial intelligence to enhance MSR assessment by making the assessment more objective, reproducible, and recordable to allow a more precise and/or personalized approach to the medical practice of individual patients via using multiple ultrasound functions and artificial intelligence to improve the accuracy and consistency of assessing reflexes and allowing MSR data to be combined with other patient medical information for improved diagnosis and management of a patient's condition.

GAS-FILLED STRUCTURES AND RELATED COMPOSITIONS, METHODS AND SYSTEMS FOR MAGNETIC RESONANCE IMAGING

Gas vesicle protein structures and related compositions, methods, and systems for singleplexed and/or multiplexed magnetic resonance imaging of a target site alone or in combination with ultrasound are described, in which the gas vesicle protein structures provide contrast for the imaging. 1. A contrast-enhanced magnetic resonance imaging method comprising:imaging a target site comprising a gas vesicle protein structure (GVPS), the GVPS containing gas having a gas susceptibility value different from a bulk material susceptibility at the target site to obtain a MRI image, the imaging comprising detecting volume susceptibilities of the target site and/or relaxation rates of nuclear spins of atoms in the bulk material.2AnabaenaHalobacterium archaeaBacillus megaterium.. The magnetic resonance imaging method of claim 1 , wherein the GVPS is a GVPS selected from a species of bacteria claim 1 , claim 1 , or3. The magnetic resonance imaging method of claim 1 , wherein the gas susceptibility is different from the bulk material susceptibility by at least 3 ppm.4. The magnetic resonance imaging method of claim 1 , wherein the GVPS is provided in a contrast agent having a concentration equal to or lower than 100 nM.5. The magnetic resonance imaging method of claim 1 , wherein the MRI image is QSM claim 1 , T2 claim 1 , T2* claim 1 , T2- or T2*-weighted map.6. A background-free magnetic resonance imaging method comprising:administering to a target site a contrast agent comprising a gas vesicle protein structure (GVPS), the GVPS containing gas having a gas susceptibility value different from a bulk material susceptibility at the target site,imaging the target site to obtain a first MRI image,collapsing the GVPS type by applying collapsing ultrasound to the target site, the collapsing ultrasound applied at a collapsing ultrasound pressure greater than a selectable acoustic collapse pressure value derived from an acoustic collapse pressure profile of the GVPS,and after collapsing, ...

Method and system for determining fractional fat content of tissue

A system and method for determining fractional fat content of tissue comprises registering thermoacoustic image coordinates to an acquired ultrasound image, the acquired ultrasound image at least comprising target tissue within a region of interest; defining a thermoacoustic voxel grid coincident with the region of interest; obtaining thermoacoustic image measurement values from tissue within the region of interest corresponding to the voxels within the defined thermoecoustic voxel grid to yield a thermoacoustic measurement matrix; normalizing the thermoacoustic image measurement values within the thermoacoustic measurement matrix; calculating a fractional fat content map for the target tissue within the region of interest based on the normalized thermoacoustic image measurement values within the thermoacoustic measurement matrix and a reference thermoacoustic measurement value; and correcting the fractional fat content map based on tissue speed-of-sound data to yield a final fractional fat content map for the target tissue within the region of interest.

METHOD, SYSTEM AND APPARATUS FOR QUANTITATIVE SURGICAL IMAGE REGISTRATION

A method in a computing device for quantitative surgical image registration includes: prior to a surgical procedure, obtaining, using a first imaging modality, a preoperative image of patient tissue and a plurality of preoperative measurements of a material property of the patient tissue. The preoperative measurements correspond to respective points in the preoperative image. The method includes storing the preoperative image and the preoperative measurements, and during the surgical procedure, using a second imaging modality, capturing an intraoperative image of the patient tissue and a second plurality of intraoperative measurements of the material property of the patient tissue. The intraoperative measurements correspond to respective points in the intraoperative image. The method includes comparing the first and second pluralities of measurements to determine a transformation for registering the preoperative image and the intraoperative image; and storing the transformation in association with one of the intraoperative image and the preoperative image. 1. A method of image registration , comprising:prior to a surgical procedure, obtaining a preoperative image of patient tissue at a computing device using a first imaging modality;using the first imaging modality, obtaining a first plurality of preoperative measurements of a material property of the patient tissue at the computing device, each measurement of the first plurality of preoperative measurements corresponding to a respective point in the preoperative image;storing the preoperative image and the preoperative measurements in a memory of the computing device;during the surgical procedure; obtaining an intraoperative image of the patient tissue at the computing device using a second imaging modality;using the second imaging modality, obtaining a second plurality of intraoperative measurements of the material property of the patient tissue at the computing device, each measurement of the second plurality of ...

METHODS AND SYSTEMS FOR DETECTING PLEURAL IRREGULARITIES IN MEDICAL IMAGES

Various methods and systems are provided for a medical imaging system. In one embodiment, a method includes acquiring a series of medical images of a lung, identifying a pleural line in each medical image of the series, evaluating the pleural line for irregularities in each medical image of the series, and outputting an annotated version of each medical image of the series, the annotated version including visual markers for healthy pleura and irregular pleura. In this way, an operator of the medical imaging system may be alerted to pleural irregularities during a scan.

System and method for lung visualization using ultrasound

A system for ultrasound interrogation of a lung includes a memory, an electromagnetic (EM) board, an extended working channel (EWC), an EM sensor, a US transducer, and a processor. The memory stores a three dimensional (3D) model, a pathway plan for navigating a luminal network. An EM board generates an EM field. The EWC is configured to navigate the luminal network of a patient toward a target following the pathway plan and the EM sensor extends distally from the EWC and senses the EM field. The US transducer extends distally from a distal end of the EWC and generates US waves and receives US waves reflected from the luminal network and the processor processes the sensed EM field to synchronize a location of the EM sensor in the 3D model, to process the reflected US waves to generate images, or to integrate the generated images with the 3D model.

SYSTEM AND METHOD FOR LUNG VISUALIZATION USING ULTRASOUND

A system for ultrasound interrogation of a lung including a memory, an electromagnetic (EM) board, an extended working channel (EWC), an EM sensor, a US transducer, and a processor. The memory stores a three dimensional (3D) model and pathway plan for navigating a luminal network. The EM board generates an EM field. The EWC is configured to navigate the luminal network toward a target following the pathway plan. The EM sensor extends distally from a distal end of the EWC and is configured to sense the EM field. The US transducer extends distally from a distal end of the EWC, generates US waves, and receives US waves reflected from the luminal network. The processor processes the sensed EM field to synchronize a location of the EM sensor in the 3D model, to process the reflected US waves to generate images, or to integrate the generated images with the 3D model. 1. A system for ultrasound (US) interrogation comprising:a memory storing a three dimensional (3D) model of a luminal network and a pathway plan for navigating a luminal network;an electromagnetic (EM) board configured to generate an EM field;an extended working channel (EWC) configured to navigate the luminal network toward a target in accordance with a pathway plan;an EM sensor extending distally from a distal end of the EWC and configured to sense the EM field;a US transducer configured to generate US waves and receive US waves reflected from the luminal network; anda processor configured to process the sensed EM field to synchronize a location of the EM sensor in the 3D model, to process the reflected US waves to generate US images, or to integrate the generated images with the 3D model.2. The system according to claim 1 , further comprising a display device configured to display the integrated 3D model and US images.3. The system according to claim 2 , wherein the display is further configured to display a status based on the location of the EM sensor.4. The system according to claim 3 , wherein the ...

Probe and imaging apparatus for diagnosis

A probe includes a transmitting and receiving unit in which an ultrasonic wave transmitting and receiving unit and a light transmitting and receiving unit are arranged. The ultrasonic wave transmitting and receiving unit and the light transmitting and receiving unit are arranged along an axial direction. A distance L [mm] between a position of the ultrasonic wave transmitting and receiving unit in the axial direction and a position of the light transmitting and receiving unit in the axial direction, and the angular difference θ [degrees] between a transmit direction of an ultrasonic wave of the ultrasonic wave transmitting and receiving unit and a transmit direction of light of the light transmitting and receiving unit satisfy a relationship of L=V/ω×θ/360 when having a rotary velocity ω [r/s] of the transmitting and receiving unit 221 and a movement velocity V [mm/s] of the transmitting and receiving unit 221 in the axial direction.

Medical information processing system and medical information processing method

According to one embodiment, a medical information processing system includes processing circuitry. The processing circuitry acquires an ultrasound image of a subject. The processing circuitry acquires a first modality image of the subject, the first modality image differing from the ultrasound image. The processing circuitry acquires an imaging position for the ultrasound image. The processing circuitry generates diagnosis support information for the subject based on the ultrasound image, the imaging position for the ultrasound image, and the first modality image.

APPARATUS, METHODS AND COMPUTER-ACCESSIBLE MEDIA FOR IN SITU THREE-DIMENSIONAL RECONSTRUCTION OF LUMINAL STRUCTURES

An apparatus for determining a shape of a luminal sample including: a catheter including a lens, the catheter disposed within a strain-sensing sheath such that the lens rotates and translates; a structural imaging system optically coupled to the catheter; a strain-sensing system optically coupled to the catheter; and a controller coupled to the strain-sensing system and the structural imaging system. The controller determines: a first position of the catheter relative to the luminal sample at a first location within the strain-sensing sheath; a second position of the catheter relative to the luminal sample at a second location within the strain-sensing sheath; a first strain of the strain-sensing sheath at the first location; a second strain of the strain-sensing sheath at the second location; a local curvature of the luminal sample relative to the catheter; a local curvature of the catheter; and a local curvature of the luminal sample. 1. An apparatus , comprising:at least one optical waveguide that emits electromagnetic radiation comprising a first electromagnetic radiation and a third electromagnetic radiation,a scanning arrangement that at least one of rotates and translates to direct the electromagnetic radiation, 'the strain-sensing sheath comprising a strain-sensing system optically coupled to the at least one waveguide; and', 'a strain-sensing sheath that at least partially encloses the at least one optical waveguide and the scanning arrangement,'} [ transmitting the first electromagnetic radiation towards the strain-sensing sheath,', 'obtaining a second electromagnetic radiation from the strain-sensing sheath based on fluorescence excited by the first electromagnetic radiation, and', 'determining the first strain based on obtaining the second electromagnetic radiation, and, 'determine a first strain of the strain-sensing sheath at a first location by, transmitting the third electromagnetic radiation towards the strain-sensing sheath,', 'obtaining a fourth ...

IMAGE PROCESSING METHOD AND APPARATUS AND PROGRAM

An image processing method for performing registration between a first medical image and a second medical image both being three-dimensional images is provided. The image processing method includes extracting a first vascular image in the first medical image and a second vascular image in the second medical image, detecting at least one vascular portion structure including a plurality of vascular portions close or connected to each other with respect to each of the first and second vascular images extracted, for each of a plurality of combinations of the at least one vascular portion structure in the first vascular image and the at least one vascular portion structure in the second vascular image, performing coordinate transformation on at least one of the first and second vascular images such that a deviation between the vascular portion structures becomes small, and calculating similarity in a prescribed area including the vascular portion structures between the first and second vascular images, and performing coordinate transformation for the registration using the coordinate transformation highest in the calculated similarity. 1. An image processing method for performing registration between a first medical image and a second medical image both being three-dimensional images , the image processing method comprising:extracting a first vascular image in the first medical image and a second vascular image in the second medical image;detecting at least one vascular portion structure including a plurality of vascular portions close or connected to each other with respect to each of the first and second vascular images extracted;for each of a plurality of combinations of the at least one vascular portion structure in the first vascular image and the at least one vascular portion structure in the second vascular image, performing coordinate transformation on at least one of the first and second vascular images such that a deviation between the vascular portion ...

MEDICAL IMAGING APPARATUS AND METHOD OF OPERATING SAME

Provided is a method of operating a medical imaging apparatus, comprising: acquiring a first image of a first type corresponding to a first respiratory state of an object; determining motion information of the object with respect to a respiratory state, based on first and second images of a second type respectively corresponding to the first respiratory state and a second respiratory state of the object; and generating a second image of the first type corresponding to the second respiratory state by applying the motion information to the first image of the first type. 1. A method of operating a medical imaging apparatus , the method comprising:acquiring a first image of a first type corresponding to a first respiratory state of an object;acquiring a first ultrasound image corresponding to the first respiratory state of the object and a second ultrasound image corresponding to a second respiratory state of the object;generating a second image of the first type in which the second respiratory state of the object is predicted, based on anatomical information extracted from the first ultrasound image and the second ultrasound image; andregistering the second image of the first type and the second ultrasound image.2. The method of claim 1 , wherein the generating the second image of the first type comprisespredicting a second anatomical information corresponding to the second respiratory state of the object from a first anatomical information corresponding to the first respiratory state of the object in the first image of a first type, based on the anatomical information extracted from the first ultrasound image and the second ultrasound image; andgenerating the second image of the first type based on the second anatomical information.3. The method of claim 2 , wherein the predicting the second anatomical information comprisesdetermining motion information of the object with respect to a respiratory state, based on the anatomical information extracted from the first ...

Method and Device for Displaying an Object

A method and a device for displaying an object, in particular biological tissue. The method has the following steps: a) generating a first image of at least one sub-region of the object using a first device; b) generating a second image of at least one sub-region of the object using a second device; c) ascertaining first coordinates of at least some image points of the second image in a first coordinate system; d) ascertaining second coordinates of the image points of the second image by projecting the first coordinates in a second coordinate system which is different from the first coordinate system and which is assigned to the first device; and e) generating a combined image of the object from the first and the second image using the ascertained second coordinates of the image points of the second image. 1a) generating a first image of at least one sub-region of the object by means of a first intraoperative imaging device;b) generating a second image of at least one sub-region of the object by means of a second intraoperative imaging device;c) ascertaining first coordinates of at least some image points of the second image in a first coordinate system;d) ascertaining second coordinates of at least some of the image points of the second image by projecting the first ascertained coordinates in a second coordinate system which is different from the first coordinate system and which is assigned to the first device; and with a multitude of light spots as supporting points, wherein the endoscopy device comprises a navigated light source, or', 'by marking a sub-region of the object of interest with a plurality of supporting points with a separate position determining device,', 'so that generation of the combined image is achieved following the marking process by replacing or overlaying image points of the first image within the selected sub-region of interest with image points of the second image., 'e) generating a combined image of the object from the first and the ...

SCAN ALIGNMENT BASED ON PATIENT-BASED SURFACE IN MEDICAL DIAGNOSTIC ULTRASOUND IMAGING

Imaging from sequential scans is aligned based on patient information. A three-dimensional distribution of a patient-related object or objects, such as an outer surface of the patient or an organ in the patient, is stored with any results (e.g., images and/or measurements). Rather than the entire scan volume, the three-dimensional distributions from the different scans are used to align between the scans. The alignment allows diagnostically useful comparison between the scans, such as guiding an imaging technician to more rapidly determine the location of a same lesion for size comparison. 1. A method for aligning scans from different times with a medical imager , the method comprising:scanning a patient at a first time, the scanning resulting in first scan data representing the patient at the first time;scanning, by the medical imager, the patient at a second time, the scanning resulting in second scan data representing the patient at the second time, the second time being for a different imaging session than the first time;generating a first surface in three-dimensions, the first surface representing the patient at the first time;generating a second surface in three-dimensions, the second surface representing the patient at the second time;determining a spatial transformation between the first surface and the second surface;comparing first information from the first scan data with second information from the second scan data based on the spatial transformation; anddisplaying an image of the first and second information.2. The method of wherein generating the first and second surfaces comprises generating the first and second surfaces as outer surfaces of the patient.3. The method of wherein generating the first and second surfaces comprises generating with a depth camera.4. The method of wherein generating the first and second surfaces comprises generating the outer surfaces from the first and second scan data.5. The method of wherein generating the first and ...

IMAGE REGISTRATION FOR CT OR MR IMAGERY AND ULTRASOUND IMAGERY USING MOBILE DEVICE

A method for fusion of live ultrasound imagery with computed tomography (CT) scan images or magnetic resonance images, the method comprising steps of acquiring a series of CT scan images or magnetic resonance images, acquiring a series of ultrasound images, applying a manual registration process on a computing device to register each of the CT scan images or magnetic resonance images with corresponding ultrasound images, and displaying on a display associated with the computing device the live ultrasound imagery and corresponding CT scan images or magnetic resonance images. 1. A method for fusion of live ultrasound imagery with computed tomography (CT) scan images or magnetic resonance images , the method comprising steps of:acquiring a series of CT scan images or magnetic resonance images;acquiring a series of ultrasound images;applying a manual registration process on a computing device to register each of the CT scan images or magnetic resonance images with corresponding ultrasound images; anddisplaying on a display associated with the computing device the live ultrasound imagery and corresponding CT scan images or magnetic resonance images.2. The method of wherein the manual registration process comprise displaying to a user on a display a CT scan image or magnetic resonance image claim 1 , displaying a plurality of ultrasound images to the user on the display and receiving a selection from the user of one of the plurality of ultrasound images corresponding with the CT scan image or the magnetic resonance image.3. The method of wherein the manual registration process further comprises receiving from the user a tracing of contours of an organ displayed on the display.4. The method of wherein the manual registration process further comprises receiving from the user a tracing of contours of a region of interest displayed on the display.5. The method of wherein the series of CT scan images or magnetic resonance images and the series of ultrasound images are renal ...

APPARATUS AND METHODS OF MONITORING MATERNAL AND FETAL HEART RATE

Systems and methods of maternal and fetal monitoring include acquiring ultrasound physiological data with an ultrasound transducer. A plurality of electrodes acquire biopotential physiological data from the skin of a patient. A controller receives the ultrasound and biopotential physiological data and calculates fetal heart rate (fHR) values, maternal heart rate (mHR) values, and uterine activity (UA) values from the ultrasound and biopotential physiological data. 1. A maternal and fetal monitoring system comprising:an ultrasound transducer that acquires ultrasound physiological data;a plurality of electrodes that acquire biopotential physiological data;a controller that receives the ultrasound and biopotential physiological data and calculates fetal heart rate (fHR)values, maternal heart rate (mHR) values, and uterine activity (UA) values from the ultrasound and biopotential physiological data; anda graphical display communicatively connected to the controller to receive and visually present the calculated fHR values, mHR values, and UA values.2. The maternal and fetal monitoring system of claim 1 , wherein the controller calculates first values of fHR claim 1 , mHR claim 1 , and UA from the biopotential physiological data and the controller calculates second values of fHR claim 1 , mHR claim 1 , and UA from the ultrasound physiological data claim 1 , and the first values or the second values are selected as the calculated fHR values claim 1 , mHR values claim 1 , and UA values presented on the graphical display.3. The maternal and fetal monitoring system of claim 2 , wherein the controller further calculates a biopotential signal to noise ratio (SNR) from the biopotential physiological data claim 2 , calculates an ultrasound SNR from the ultrasound physiological data claim 2 , and selects between the first values of fHR claim 2 , mHR claim 2 , and UA and the second values of fHR claim 2 , mHR claim 2 , and UA based upon the greater of the biopotential SNR and the ...

INTEGRATED IMAGING COMPONENT AND INTRAVASCULAR DEVICE DELIVERY SYSTEM

An apparatus and method for the intravascular placement of a filter includes an outer shaft with marker boards, an inner shaft, an intravascular ultrasound catheter with an ultrasonic imaging element, and the filter that is to be deployed. The ultrasound imaging element is enclosed within a proximal and distal transducer capsule configured to support the electronics of wiring of the element and provide for ease of insertion and withdrawal of the catheter. A guide wire is enclosed by and is moveable relative to the ultrasound catheter. In the stored position, the filter is secured adjacent to the distal inner shaft and proximal to the ultrasound catheter. When the apparatus is introduced into the vasculature, the ultrasound catheter provides real-time imaging of the vessel for identifying the appropriate location for placement of the filter. Once such a location has been identified, the filter is deployed and optionally, the ultrasonic imaging element used to confirm position, placement deployment of the filter. 1. An intravascular imaging capsule , comprising:an imaging component mounted on a support frame with a proximal end and a distal end having a base adapted and configured to at least partially encircle a support tube, a proximal facing shoulder mount and a distal facing shoulder mount;a distal tip having a distal end and a proximal end and a lumen extending from the proximal end to the distal end wherein a proximal portion of the lumen is sized to fit over a portion of the distal facing shoulder mount and a distal portion of the lumen is sized to have an inner diameter of about the same size as an inner diameter of the support tube; andproximal cap having a distal end and a proximal end and a lumen extending from the proximal end to the distal end sized to be greater than the largest cross section dimension of the support tube wherein a distal portion of the lumen is sized to fit over a portion of the proximal facing shoulder mount.2. The capsule of wherein ...

SINUPLASTY TOOL

A sinuplasty tool, consisting of a handle, and a rigid tube, containing a rigid tube lumen, having a rigid tube distal end and a rigid tube proximal end connected to the handle. The tool also has a resilient tube, containing a resilient tube lumen, having a resilient tube distal end and a resilient tube proximal end fixed to the rigid tube distal end so that the lumens align. The resilient tube has a multiplicity of separated openings partially encircling the resilient tube so as to form ribs in the resilient tube and permitting the resilient tube to bend. The resilient tube distal end may be inserted into a sinus of a living subject. The tool also has a wire, traversing the aligned lumens, connected to the resilient tube distal end and coupled to the handle, so that applying tension to the wire causes the resilient tube to bend. 1. A sinuplasty tool , comprising:a handle;a rigid tube, containing a rigid tube lumen, having a rigid tube distal end and a rigid tube proximal end connected to the handle;a resilient tube, containing a resilient tube lumen, having a resilient tube distal end and a resilient tube proximal end fixedly attached to the rigid tube distal end so that the resilient tube lumen and the rigid tube lumen align, the resilient tube having a multiplicity of separated openings partially encircling the resilient tube so as to form ribs in the resilient tube and permitting the resilient tube to bend, the resilient tube distal end being configured to be inserted into a sinus of a body of a living subject; anda wire, traversing the aligned lumens, connected to a region in proximity to the resilient tube distal end and coupled to the handle, so that applying tension to the wire causes the resilient tube to bend.2. The sinuplasty tool according to claim 1 , and comprising locking elements claim 1 , formed on the ribs claim 1 , configured to interlock the ribs when the resilient tube is fully bent.3. The sinuplasty tool according to claim 1 , and comprising a ...

Statistical Mapping in an Optoacoustic Imaging System

Electromagnetic energy is deposited into a volume, an acoustic return signal from energy deposited in the volume is measured, and a parametric map that estimates values of at least one parameter as spatially represented in the volume is computed. A reference level of a region of interest is determined, and upper and lower color map limits are specified, with at least one of them being determined in relation to the reference level. The parametric map is then rendered in the palette of a color map by mapping the estimated values of the parametric map onto the color map according to the color map limits. Two wavelengths of energy can be applied to the volume, and the parametric map computation can be adapted by applying an implicit or explicit model of, or theoretical basis for, distribution of electromagnetic energy fluence within the volume pertaining to the two wavelengths. The actual electromagnetic energy fluence caused by each wavelength has a propensity, due to variability within the volume, to differ from the modeled or theoretical electromagnetic energy fluence. 1. A method to produce a qualitative image , comprising:depositing electromagnetic energy into the volume using one or more energy sources to deposit at least two wavelengths of electromagnetic energy into the volume so as to provide a source of molecular contrast for a parametric map;measuring acoustic return signals from energy deposited in the volume;computing a parametric map that estimates values of at least one parameter as spatially represented in the volume; i) determining at least one reference level within at least one region of interest of the parametric map; and', 'ii) specifying an upper color map limit and a lower color map limit, at least one of the upper color map limit or the lower color map limit being determined in relation to the at least one reference level; and,, 'producing a mapping configuration to adjust for effects resulting from at least some of the variability in the spatial ...

Method and apparatus for registering medical images

A method for registering medical images of different types, includes: receiving a selection of at least one point in a first medical image that is acquired in non-real time; extracting, from the first medical image, a first anatomic object which includes the selected point and a second anatomic object which is adjacent to the selected point; extracting, from a second medical image that is acquired in real time, a third anatomic object which corresponds to the first anatomic object and a fourth anatomic object which corresponds to the second anatomic object; and registering the first medical image and the second medical image based on a geometric relation between the first, second, third, and fourth anatomic objects.

CARDIAC MAPPING AND NAVIGATION FOR TRANSCATHETER PROCEDURES

The invention is a device, system, and method for imaging heart features and deploying implants therein, such as prosthetic heart valves. The invention uses 3D imaging with electrophysiological imaging, combined with prosthetic heart valve deployment. Real-time imaging vie ECHO or fluoroscopy or other real-time methods may be provided with the 3D image generated by the imaging system. 1. A method for delivering a prosthetic heart valve within a patient , comprising:advancing an electrophysiological mapping catheter into the patient to a position adjacent a native heart valve annulus;collecting mapping data from an area adjacent the native heart valve annulus with the electrophysiological mapping catheter;activating a 3D imaging system to present a display of the area adjacent the native heart valve annulus using the mapping data, wherein the display comprises a 3D image derived from the mapping data;advancing a distal end of a prosthetic heart valve delivery catheter into the patient to a position adjacent the native heart valve annulus, wherein the prosthetic heart valve delivery catheter has a prosthetic heart valve positioned at the distal end thereof;monitoring the location and orientation of the prosthetic heart valve and/or prosthetic heart valve delivery catheter within the patient via the display of the 3D image of the area adjacent the native heart valve annulus; anddeploying the prosthetic heart valve within the native heart valve annulus.2. The method of claim 1 , further comprising:providing real-time imaging of tissue at and adjacent the native valve annulus; andactivating the 3D imaging system to add the real-time imaging to the display.3. The method of claim 2 , wherein the real-time imaging of tissue is provided via a fluoroscopic system.4. The method of claim 3 , further comprising:after deployment of the prosthetic heart valve, monitoring the performance of the prosthetic heart valve via the fluoroscopic system.5. The method of claim 2 , wherein ...

METHODS AND SYSTEMS FOR VALVE REGURGITATION ASSESSMENT

The invention provides a method for assessing cardiac valve regurgitation. The method includes obtaining 4D ultrasound data of a region of interest, wherein the region of interest comprises a cardiac valve. The 4D ultrasound data comprises a time sequence of 3D ultrasound images comprising B-mode ultrasound data and color Doppler ultrasound data. Image stabilization is performed on the images of the time sequence of 3D ultrasound images and a dynamic jet is then segmented from the time sequence of stabilized 3D ultrasound images. A dynamic surface model is fit to the valve in the time sequence of stabilized 3D ultrasound images based on the segmented jet. The method further includes identifying a dynamic regurgitant orifice based on the applied surface model and the time sequence of stabilized 3D ultrasound images and fitting a flow convergence model to the time sequence of stabilized 3D ultrasound images based on the identified dynamic regurgitant orifice. A regurgitant flow is then estimated based on the identified regurgitant orifice. 1. A method for calculating cardiac valve regurgitation , the method comprising:obtaining 4D ultrasound data of a region of interest, wherein the region of interest comprises a cardiac valve and wherein the 4D ultrasound data comprises a time sequence of 3D ultrasound images comprising B-mode ultrasound data and color Doppler ultrasound data;performing image stabilization on the images of the time sequence of 3D ultrasound images;segmenting a dynamic jet from the time sequence of stabilized 3D ultrasound images;fitting a dynamic surface model to the valve in the time sequence of stabilized 3D ultrasound images based on the segmented dynamic jet;identifying a dynamic regurgitant orifice based on the dynamic surface model and the time sequence of stabilized 3D ultrasound images;fitting a flow convergence model to the time sequence of stabilized 3D ultrasound images based on the identified dynamic regurgitant orifice; andestimating a ...

Continuous autoregulation system

A method for measuring an intracranial bioimpedance in a patient's head, to help evaluate cerebral autoregulation, may involve securing a volumetric integral phase-shift spectroscopy (VIPS) device to the patient's head, measuring the intracranial bioimpedance with the VIPS device by measuring a phase shift between a magnetic field transmitted from a transmitter on one side of a VIPS device and a magnetic field received at a receiver on another side of the VIPS device, at one or more frequencies, and evaluating cerebral autoregulation in the intracranial bioimpedance, using a processor in the VIPS device.

METHODS AND PROBES FOR VAGINAL TACTILE AND ULTRASOUND IMAGING

A vaginal probe is equipped with tactile sensors and ultrasound elements and configured for simultaneous acquisition of tactile images and ultrasound images for the same portion of vaginal tissues and pelvic floor muscles. The probe is configured for placement into vagina to record tactile images and ultrasound images in static, during tissue deformation as well as pelvic floor muscle contraction. Acquired and recorded tactile data are transmitted to a data processor for composing elasticity images of pelvic floor structures and muscle functional images and visually presenting thereof on a display. 1. A method for vaginal tactile and ultrasound imaging , said method comprising the steps of:a) providing a vaginal probe equipped with a plurality of tactile sensors and a plurality of ultrasound elements positioned adjacent thereto,b) inserting said vaginal probe into a vagina along a vaginal canal, andc) simultaneously acquiring tactile images representing tissue stress and ultrasound images representing tissue strain for the same portion of vaginal and pelvic floor tissues during vaginal wall deformations.2. The method as in claim 1 , wherein said step (c) is performed during pelvic floor muscle contractions.3. The method as in claim 1 , wherein said step (c) is performed while manipulating said vaginal probe inside the vaginal canal.4. The method as in further comprising a step (d) of composing an elasticity image using said tactile images and said ultrasound images.5. The method as in claim 4 , wherein said step (d) further comprising composing said tissue elasticity images using tissue stress data derived from said tactile images and tissue strain data derived from said ultrasound images.6. The method as in further comprising a step of presenting said tactile images and said ultrasound images either separately or overlaid together on a display.7. The method as in further comprising a step (e) of composing pelvic floor muscle functional images from said tactile ...

Object information acquiring apparatus

An object information acquiring apparatus comprises a light irradiation unit configured to irradiate an object with light; a sound generating member arranged between the object and the light irradiation unit and configured to generate a substantially planar ultrasonic wave based on the irradiated light; an acoustic wave probe configured to acquire an acoustic wave generated inside the object due to the light and convert the acoustic wave into a first electric signal; and an information generating unit configured to generate information concerning optical characteristics of an interior of the object, based on the first electric signal, wherein the sound generating member allows a part of the light irradiated from the light irradiation unit to pass through the sound generating member to the object.

ULTRASONIC IMAGING SYSTEM

An ultrasonic imaging system includes an ultrasonic probe and a processing unit. The ultrasonic probe is operable at multiple different tilt angles to perform ultrasonic measurement and to obtain a plurality 2D ultrasonic images corresponding respectively to the different tilt angles. The processing unit calculates a 3D ultrasonic images based on the 2D ultrasonic images and the corresponding tilt angles. 1. An ultrasonic imaging system , comprising:an ultrasonic probe operable at multiple different tilt angles that are defined by coplanar lines to send ultrasonic signals into a test target and to receive reflected ultrasonic signals corresponding to the ultrasonic signals from the test target; anda processing unit electrically coupled to said ultrasonic probe for controlling said ultrasonic probe to send the ultrasonic signals and to receive the reflected ultrasonic signals, and configured to generate a plurality of two-dimensional (2D) ultrasonic images that respectively correspond to the different tilt angles based on the reflected ultrasonic signals, and to generate a three-dimensional (3D) ultrasonic image based on the 2D ultrasonic images and the different tilt angles.2. The ultrasonic imaging system of claim 1 , further comprising an inertial measurement unit (IMU) mounted to said ultrasonic probe in such a way that said IMU tilts at a same angle as said ultrasonic probe claim 1 , and configured to detect acceleration components respectively corresponding to three axial directions that are defined with respect to said IMU;wherein said processing unit is electrically coupled to said IMU for receiving, when said ultrasonic probe is at each of the tilt angles, the acceleration components generated by said IMU at the tilt angle, and calculates the tilt angle based on the acceleration components corresponding to the tilt angle.4. The ultrasonic imaging system of claim 3 , wherein the 2D ultrasonic images respectively correspond to multiple sections of the test ...

Synthesizing and Segmenting Cross-Domain Medical Images

Systems and methods for generating synthesized images are provided. An input medical image of a patient in a first domain is received. A synthesized image in a second domain is generated from the input medical image of the patient in the first domain using a first generator. The first generator is trained based on a comparison between segmentation results of a training image in the first domain from a first segmentor and segmentation results of a synthesized training image in the second domain from a second segmentor. The synthesized training image in the second domain is generated by the first generator from the training image in the first domain. The synthesized image in the second domain is output.

METHOD AND SYSTEM FOR PATIENT-SPECIFIC MODELING OF BLOOD FLOW

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patients heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. 1184-. (canceled)185. A method for assessing cardiac hemodynamic information , comprising:generating or acquiring anatomic information comprising at least a location and topology of a narrowing of a blood vessel;generating or acquiring blood flow information comprising at least flow information in one or more vessels proximal to the location of the narrowing; andestimating a myocardial fractional flow reserve based at least on the anatomic information and the blood flow information.186. The method of claim 185 , comprising:employing a computed tomography (CT) system to generate a set of CT image data;determining a cardiac phase of interest using the set of CT image data;segmenting the coronary arteries from one or more CT images at the cardiac phase of interest; andderiving the anatomic information based at least on the segmented coronary arteries.187. The method of claim 186 , comprising:employing an ultrasound system to generate a set of ultrasound data; andregistering the ultrasound data based on the cardiac phase of interest.188. The method of claim 185 , comprising:employing a system to generate a set of image data;determining a cardiac phase of interest using the set of image data;segmenting the coronary arteries from one or more reconstructed images at the cardiac phase of interest; andderiving the anatomic information based at ...

Method and system for image processing and patient-specific modeling of blood flow

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.

Image Fusion-Based Tracking without a Tracking Sensor

An ultrasound imaging system include a console with transmit circuitry configured to generate an excitation electrical pulse that excites transducer elements of a probe to produce an ultrasound pressure field and configured to receive an echo signal generated in response to the ultrasound pressure field interacting with tissue. The console further includes receive circuitry configured to convert the echo signal into an electrical signal, and an echo processor configured to generate a live ultrasound image based on the electrical signal into. The console further includes a tracking processor configured to extract, in real-time, a feature common to both the live ultrasound image and previously generated volumetric image data from at least the live ultrasound image, and register, in real-time, the live ultrasound image with previously generated volumetric image data based on the common feature extracted in real-time to create the fused image. A display displays the fused image.

Patient bearing system, a robotic system

A patient bearing system and a robotic system are disclosed. The patient bearing system includes a patient bearing and at least one ultrasound transducer with an ultrasound head at least partly located in the patient bearing and being spatially located to transmit ultrasound signals to a target space. The ultrasound head is at least partly located in the patient bearing. The robotic system includes a patient bearing system and a robot configured for at least partly operate the system and the computer system is programmed for performing image acquisitions and analysis of a body part at least partly located in target space.

Imaging with Infrared Imaging Signals

An infrared imaging signal is generated. An image of an exit signal of the infrared imaging signal is captured. The infrared imaging signal is within a frequency band. 1. An imaging device comprising:an emitter for emitting infrared light within a frequency band;a display pixel array including a plurality of pixels, each pixel in the plurality of pixels is individually configurable to modulate an amplitude of the infrared light received from the emitter to generate an infrared holographic imaging signal according to a holographic pattern driven onto the display pixel array; andan image pixel array including a plurality of imaging pixels configured to receive incident light within the frequency band and reject light outside of the frequency band.2. The imaging device of further comprising:a reference wavefront generator configured to illuminate the image pixel array with a reference wavefront in response to receiving an activation signal, the reference wavefront generator to illuminate the image pixel array during a time period overlapping with a capturing of an infrared image by the image pixel array, wherein the reference wavefront is within the frequency band.3. The imaging device of claim 2 , wherein the reference wavefront generator receives the infrared light from the emitter claim 2 , and wherein the emitter is a laser and the frequency band is monochromatic infrared light.4. The imaging device of further comprising:a directional ultrasonic emitter configured to dynamically focus an ultrasonic signal to a given voxel in three-dimensional space, wherein the directional ultrasonic emitter is configured to focus the ultrasonic signal to a first voxel in three-dimensional space while the holographic pattern is driven onto the display pixel array and while an infrared image is captured with the image pixel array.5. The imaging device of claim 1 , wherein the image pixel array is positioned to image an exit signal generated by the infrared holographic imaging signal ...

METHOD AND SYSTEM FOR IMAGE PROCESSING TO DETERMINE BLOOD FLOW

Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model. 1184-. (canceled)185. A medical image diagnostic apparatus for processing medical images , comprising:processing circuitry configured to acquire data of a plurality of Fractional Flow Reserve (FFR) distribution maps comprising at least two time phases regarding a coronary artery; anda display configured to display a representation of the at least one FFR distribution map in phase to the at least one FFR distribution map, wherein the processing circuitry restricts display objects displayed by the display for the representation of the at least one FFR distribution map based on the at least one FFR distribution map.186. The medical image diagnostic apparatus according to claim 185 , wherein the processing circuitry acquires data of a plurality of morphological images comprising the at least two time phases claim 185 , and converts the at least one FFR distribution map into a at least one corresponding color map claim 185 , respectively claim 185 , and the display displays a plurality of superimposed images claim 185 , as the representation of the at least one FFR distribution map claim 185 , obtained by superposing the at least one color map and the plurality of morphological images respectively corresponding in phase.187. The medical image diagnostic apparatus according to claim 186 , wherein the processing circuitry restricts display ...

SYSTEM AND METHOD FOR PREDICTIVE FUSION

An image fusion system provides a predicted alignment between images of different modalities and synchronization of the alignment, once acquired. A spatial tracker detects and tracks a position and orientation of an imaging device within an environment. A predicted pose of an anatomical feature can be determined, based on previously acquired image data, with respect to a desired position and orientation of the imaging device. When the imaging device is moved into the desired position and orientation, a relationship is established between the pose of the anatomical feature in the image data and the pose of the anatomical feature imaged by the imaging device. Based on tracking information provided by the spatial tracker, the relationship is maintained even when the imaging device moves to various positions during a procedure 1. A system , comprising: obtain feature information indicative of a pose of a feature in a first image of a first modality;', 'obtain tracking information from a spatial tracker configured to identify a position and orientation of an imaging device producing images of a second modality; and', 'determine when a pose of the imaging device matches a predetermined pose suitable to produce a second image of the feature having a pose that matches a reference pose of the feature based on at least one of the feature information or the tracking information., 'a processor coupled to memory storing computer-executable instructions that, when executed by the processor, configure the processor to2. The system of claim 1 , wherein the processor is further configured to update claim 1 , responsive to movement of the imaging device claim 1 , an indication of the pose of the feature in the second image produced by the imaging device based on at least one of the tracking information or the feature information.3. The system of claim 2 , wherein the processor is further configured to:obtain a relationship between the pose of the imaging device in space and a pose of ...

FUSED ULTRASOUND AND MAGNETIC RESONANCE IMAGING APPARATUS

An apparatus includes a housing, an ultrasound transducer in the housing and positioned to direct ultrasound signals to a volume of a subject and detect reflected ultrasound signals from the volume of the subject, a magnet arranged in the housing and positioned such that a magnetic field of the magnet penetrates the volume of the subject, a radiofrequency (RF) system to perturb a nuclear spin polarization of nuclei in the volume of the subject and detect radio waves emitted from the volume, and an electronic controller programmed to compile an image of at least a first region of the subject based on the detected ultrasound signals and compile a magnetic resonance image of at least a second region of the subject based on the detected radio waves. 1. An apparatus , comprising:a housing comprising a first surface;an ultrasound transducer arranged in the housing and positioned relative to the first surface to direct ultrasound signals to a volume of a subject external to the housing adjacent the first surface and detect reflected ultrasound signals from the volume of the subject responsive to the directed ultrasound signals during operation of the apparatus;a magnet arranged in the housing and positioned relative to the first surface such that a magnetic field of the magnet penetrates the volume of the subject external to the housing adjacent to the first surface;a radiofrequency (RF) system comprising one or more RF coils arranged in the housing and positioned relative to the first surface to perturb a nuclear spin polarization of nuclei in the volume of the subject and detect radio waves emitted from the volume of the subject in response to the perturbations during operation of the apparatus; andan electronic controller in communication with the ultrasound transducer and the RF system, the electronic controller being programmed to compile an image of at least a first region of the subject based on the detected ultrasound signals and compile a magnetic resonance image ...

Position measurement device, treatment system including the same, and position measurement method

To provide a position measurement device capable of measuring a target position with high accuracy according to an ultrasonic image during treatment, a treatment system including the device, and a position measurement method. A first image is constructed according to an ultrasonic waveform acquired by an ultrasonic sensor 104 C, a three-dimensional image acquired in advance and the first image are collated on the basis of sensor position information acquired by a sensor position measurement unit 105 to calculate sound velocities of each body tissue of a patient 100 , a second image is constructed according to the ultrasonic waveform acquired by the ultrasonic sensor 104 C using the calculated sound velocities of each body tissue of the patient 100 , and a target tissue position is calculated according to the second image.

BIOPSY WORKFLOW USING MULTIMODAL IMAGING

The subject matter discussed herein relates to multi-modal image alignment to facilitate biopsy procedures and post-biopsy procedures. In one such example, prostate structures (or other suitable anatomic features or structures) are automatically segmented in pre-biopsy MR and pre-biopsy ultrasound images. Thereafter, pre-biopsy MR and pre-biopsy ultrasound contours are aligned. To account for non-linear deformation of the imaged anatomic structure, a patient-specific transformation model is trained via deep learning based at least in part on the pre-biopsy ultrasound images. The pre-biopsy ultrasound images that are overlaid with the pre-biopsy MR contours and based off the deformable transformation model are then aligned with the biopsy ultrasound images. Such real-time alignment using multi-modality imaging techniques provides guidance during the biopsy and post-biopsy system. 1. A multi-modal imaging method to generate a patient-specific transformation model , comprising the steps of:acquiring pre-biopsy magnetic resonance (MR) image data and pre-biopsy ultrasound image data of a patient;segmenting an anatomic region of interest and one or more lesions in an MR volume generated from the MR image data;segmenting the anatomic region of interest in an ultrasound volume generated from the ultrasound image data;aligning contours of the segmented anatomic region of interest in the MR volume with corresponding contours of the anatomic region of interest in the ultrasound volume to generate a pre-biopsy volume in which the MR volume and the ultrasound volume are aligned and on which contours of the one or more lesions from the MR volume are aligned;training a deep learning transformation model based at least in part on the pre-biopsy ultrasound image data to create a deformable transformation model specific to the patient.2. The method of claim 1 , wherein the pre-biopsy MR image data claim 1 , the pre-biopsy ultrasound image data claim 1 , and the biopsy ultrasound ...

REAL-TIME TRACKING FOR FUSING ULTRASOUND IMAGERY AND X-RAY IMAGERY

A registration system includes a controller (). The controller () includes a memory () that stores instructions; and a processor () that executes the instructions. When executed, the instructions cause the controller () to execute a process that includes obtaining a fluoroscopic X-ray image (S) from an X-ray imaging system (), and a visual image (S) of a hybrid marker () affixed to the X-ray imaging system () from a camera system (). A transformation between the hybrid marker () and the X-ray imaging system () is estimated (S) based on the fluoroscopic X-ray image. A transformation between the hybrid marker () and the camera system () is estimated (S) based on the visual image. Ultrasound images from an ultrasound system () are registered (S) to the fluoroscopic X-ray image from the X-ray imaging system () based on the transformation estimated between the hybrid marker () and the X-ray imaging system (), so as to provide a fusion of the ultrasound images to the fluoroscopic X-ray image. 1100160. A registration system () that includes a controller () , the controller comprising:{'b': '162', 'a memory () that stores instructions; and'}{'b': '161', 'a processor () that executes the instructions,'}{'b': 161', '160, 'wherein, when executed by the processor (), the instructions cause the controller () to execute a process comprising{'b': 810', '190', '820', '110', '190', '140', '190, 'obtaining a fluoroscopic X-ray image (S) from an X-ray imaging system (), and a visual image (S) of a hybrid marker () affixed to the X-ray imaging system () from a camera system () separate from the X-ray imaging system ();'}{'b': 830', '110', '190', '840', '110', '140, 'estimating a transformation (S) between the hybrid marker () and the X-ray imaging system (), based on the fluoroscopic X-ray image, and estimating a transformation (S) between the hybrid marker () and the camera system () based on the visual image; and'}{'b': 850', '156', '190', '110', '190, 'registering ultrasound images ...

VESSEL GEOMETRY AND ADDITIONAL BOUNDARY CONDITIONS FOR HEMODYNAMIC FFR/IFR SIMULATIONS FROM INTRAVASCULAR IMAGING

An apparatus for modeling coronary physiology and a corresponding method are provided in which at least one diagnostic image and intravascular imaging data are co-registered and used in combination to retrieve more accurate, patient-specific vessel parameters to be used in the modeling of the vessel geometry and the fluid dynamics of the blood flow. 1. An apparatus for modeling coronary physiology , comprisingan input unit configured to receivingat least one diagnostic image of a vasculature of a patient, andintravascular image data obtained from a vessel of the vasculature;a modeling unit configured to generate, on the basis of the at least one diagnostic image, a physiological model of the patient, the physiological model comprising a model of the vessel of the vasculature;an extraction unit configured to extract at least one vessel parameter of the vessel of the vasculature from the intravascular image data; andan adaption unit configured to adapt the physiological model on the basis of the at least one vessel parameter.2. The apparatus according to claim 1 , whereinthe at least one diagnostic image is obtained using X-ray angiography.3. The apparatus according to claim 1 , whereinthe intravascular image data is obtained using intravascular ultrasound (IVUS) and/or optical coherence tomography (OCT).4. The apparatus according to claim 1 , whereinthe intravascular image data comprises a time-series of intravascular images obtained during a cardiac cycle of the patient.5. The apparatus according to claim 1 , whereinthe generating of the physiological model comprises a segmenting of the vessel of the vasculature; and whereinthe model is generated for at least one segment of the vessel.6. The apparatus according to claim 1 , whereinthe intravascular image data comprises a plurality of intravascular images, wherein each one of the plurality of intravascular image has been obtained at one of a plurality of different intravascular imaging positions along the vessel of ...

SYSTEMS AND METHODS FOR DISPLAYING MEDICAL IMAGES

Various embodiments relate to methods and systems for displaying an ultrasound image of a patient's target body portion using a wearable display module. A wearable display module can be mounted on a user's head. A wearable display module can display ultrasound images as a heads up display so that a user can view an ultrasound image while maintaining lines of sight with other viewpoints. Various embodiments relate to methods and systems for displaying both an ultrasound image and a light image (e.g., a near infrared image). A single display can be configured to display the light image and the ultrasound image on a single surface, in close proximity, and at the same time or in sequence. This disclosure provides in some embodiments for the use of wireless communication between various imaging probes, sensors, image processors, and display modules in order to facilitate more effective viewing of images. 1. A method for displaying an ultrasound image , the method comprising:identifying a target body portion of a patient to be imaged;emitting ultrasound signals from an ultrasound probe, wherein the ultrasound signals cause echo signals to be reflected from tissue within the target body portion;receiving the echo signals;generating an ultrasound image of the target body portion based at least in part on the echo signals; anddisplaying the ultrasound image on a head-mounted display.2. The method of claim 1 , further comprising:transmitting the ultrasound image to a remote display accessible to a remote healthcare professional;receiving treatment instructions from the remote healthcare professional; andadministering treatment based at least in part on the instructions from the remote healthcare professional.3. The method of claim 1 , further comprising:generating echo signal data based at least in part on the echo signals;transmitting the echo signal data wirelessly to an image processor that generates the ultrasound image.4. The method of claim 1 , further comprising ...