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05-01-2012 дата публикации

Methods to improve adhesion of polymer coatings over stents

Номер: US20120004721A1

Автор: Daniel A. Castro, Stephen D. Pacetti, Yunbing Wang

Принадлежит: Individual

Methods are disclosed to improved adhesion of polymer coatings over polymer surfaces of stents which include plasma treatment, applying an adhesion promoting layer, surface treatments with solvents, and mechanical roughening techniques.

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Номер записи: 1

13-01-2017 дата публикации

Внутрисосудистый расправляемый стент

Номер: RU0000167983U1

Автор: Александр Васильевич Ченцов, Николай Михайлович Осипенко, Роберт Вениаминович Гольдштейн

Принадлежит: Федеральное государственное бюджетное учреждение науки Институт проблем механики им. А.Ю. Ишлинского Российской академии наук (ИПМех РАН)

Полезная модель относится к медицинской технике, а именно к расширяемым медицинским имплантатам для поддержания просвета в сосудах.Технический результат - повышение устойчивости формы под действием радиального сжатия.Достигается тем, что внутрисосудистый расправляемый стент содержит гибкий трубчатый корпус, выполненный в виде соединенных между собой замкнутых контурных элементов, примыкающих друг к другу в направлении окружности и вдоль продольной оси, при этом элементы в направлении окружности образованы кольцевыми дугами, каждый из концов которых оканчивается V-образными элементами. При этом внутри V-образных элементов выполнены V-образные сквозные прорези, наружные стенки прорезей выполнены утолщенными, при этом одни концы кольцевых дуг соединены с внешними стенками V-образных прорезей, а другие с внутренними, все вершины V-образных элементов в каждом ряду направлены в одну сторону, а в соседних рядах навстречу друг другу. Замыкаются контурные элементы с помощью направленных вдоль продольной оси стента ламелей, соединяющих через один V-образные элементы в соседних рядах. 4 ил. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 167 983 U1 (51) МПК A61F 2/82 (2013.01) A61F 2/844 (2013.01) A61F 2/90 (2013.01) A61F 2/91 (2013.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ТИТУЛЬНЫЙ ЛИСТ ОПИСАНИЯ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (21)(22) Заявка: 2016121660, 01.06.2016 (24) Дата начала отсчета срока действия патента: 01.06.2016 Дата регистрации: (72) Автор(ы): Гольдштейн Роберт Вениаминович (RU), Осипенко Николай Михайлович (RU), Ченцов Александр Васильевич (RU) Приоритет(ы): (22) Дата подачи заявки: 01.06.2016 (45) Опубликовано: 13.01.2017 Бюл. № 2 1 6 7 9 8 3 R U (57) Формула полезной модели Внутрисосудистый расправляемый стент, содержащий гибкий трубчатый корпус, выполненный в виде соединенных между собой замкнутых контурных элементов, примыкающих друг к другу в направлении окружности и вдоль продольной оси, при этом элементы в рядах в направлении окружности образованы ...

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Номер записи: 2

13-02-2019 дата публикации

Проводник для установки мочеточникового стента с фиксаторами в виде "свиных хвостов"

Номер: RU0000187018U1

Автор: Андрей Николаевич Шибаев, Владимир Викторович Базаев, Леонид Семёнович Рафф, Никита Александрович Амосов, Юлия Викторовна Павлова, Юрий Германович Андреев

Принадлежит: Андрей Николаевич Шибаев, Леонид Семёнович Рафф, Юрий Германович Андреев

Предлагаемая полезная модель относится к области медицины - урологии, а в частности к конструкции проводника для установки мочеточникового стента с фиксаторами в виде «свиных хвостов» при лапароскопических и открытых операциях на верхних мочевыводящих путях.Предлагаемая полезная модель упрощает доставку стента с одновременной его точной установкой при лапароскопических операциях на верхних мочевыводящих путях при проведении стента как в дистальном, так и в проксимальном направлениях с последующим облегченным удалением проводника.Технический результат в предлагаемой полезной модели достигают созданием проводника для установки мочеточникового стента с фиксаторами в виде «свиных хвостов», который согласно изобретению содержит мягкую центральную часть, выполненную в виде нити, и жесткие дистальные концы, причем длина каждого жесткого дистального конца больше длины окружности фиксатора стента, а мягкая центральная часть длиннее расстояния между фиксаторами стента, при этом часть мягкой центральной части выполнена с возможностью расположения с наружной стороны прямой части трубки стента, жесткие дистальные концы выполнены с возможностью расправления фиксаторов стента и имеют диаметр меньше диаметра отверстий на трубке стента. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 187 018 U1 (51) МПК A61F 2/82 (2013.01) A61F 2/95 (2013.01) A61M 25/01 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (52) СПК A61F 2/82 (2018.08); A61F 2/95 (2018.08); A61M 25/01 (2018.08) (21)(22) Заявка: 2018131242, 30.08.2018 (24) Дата начала отсчета срока действия патента: Дата регистрации: 13.02.2019 (45) Опубликовано: 13.02.2019 Бюл. № 5 Адрес для переписки: 105043, Москва, ул. Первомайская, 66, кв. 135, Широковой Т.К. (73) Патентообладатель(и): Андреев Юрий Германович (RU), Рафф Леонид Семенович (RU), Шибаев Андрей Николаевич (RU) (56) Список документов, цитированных в отчете о поиске: RU 2661093 C1, 11.07.2018. RU U 1 1 8 7 0 1 8 R U (54) Проводник ...

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Номер записи: 3

12-01-2012 дата публикации

Heart valve prosthesis using different types of living tissue and method of fabricating the same

Номер: US20120010697A1

Автор: Chang-Ha Lee, Cheul Lee, Eun Ae Jo, Hong-Gook Lim, Kang Sun Hong, Kyong-Min Shin, Sam Sea Oh, Yong-Jin Kim

Принадлежит: Taewoong Medical Co Ltd

A heart valve prosthesis and a method of fabricating the same. The heart valve prosthesis uses a leaflet of pig pericardium or a leaflet of cattle pericardium, which has a suitable thickness according to the size of the valve, and a stent. The heart valve prosthesis is fabricated by placing a valve body over a Dacron body, binding the valve body to the Dacron body using stitching fiber, rolling the Dacron body into a cylindrical form such that the valve body is located inside, binding opposite edges of the Dacron body to each other using stitching fiber, and inserting the resultant structure into a stent, which is knitted using a shape memory alloy wire. The heart valve prosthesis is friendly to and is not rejected by human tissue, is free from deformation, and can be implanted using a non-invasive manner without incising the chest wall of a patient.

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Номер записи: 4

09-02-2012 дата публикации

Ring stent

Номер: US20120035710A1

Автор: David Ernest Hartley

Принадлежит: David Ernest Hartley

A stent arrangement which has at least a first ring ( 3 ) and zig zag struts ( 5 ) extending axially from the periphery of the ring. There can be first and second rings ( 3, 4 ) axially spaced apart and defining substantially parallel planes and a plurality of zig zag portions ( 5 ) between the first and second ring portions around the periphery thereof. The stent can be formed from a single wire or laser cut from a cannula and can be covered or uncovered.

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Номер записи: 5

09-02-2012 дата публикации

Stent Graft Having A Marker And A Reinforcing And Marker Ring

Номер: US20120035714A1

Автор: Chantelle King, David Ernest Hartley, Werner D. Ducke

Принадлежит: Cook Medical Technologies LLC, William A Cook Australia Pty Ltd

A reinforcing and marker ring for a stent graft is disclosed. The reinforcing and marker ring comprises a plurality of turns of a substantially inextensible resilient wire in a circular shape and terminal ends at each end of the wire. The terminal ends each comprise a loop, each loop attachable to a stent graft having an opening or a fenestration so as to substantially lock a peripheral length of the circular shape. A marker winding is wound helically around the reinforcing wire, the marker winding being viewable on an image display system employing electromagnetic radiation so as to indicate the location of a periphery of the fenestration. The circular shape of the resilient wire, with the marker winding wound around it, is collapsible under radial pressure to form a squashed circular shape for loading into a delivery device, the squashed circular shape self-expandable back to a substantially circular shape upon release from the delivery device. The marker winding defines a curved passageway around the resilient wire of the reinforcing ring, the curved passageway having an internal diameter D, wherein the marker winding is helically wound with a pitch providing at least one winding per length D along the reinforcing wire of the reinforcing ring. The marker winding may be a radiopaque gold wire wound around a nitinol reinforcing wire.

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Номер записи: 6

09-02-2012 дата публикации

Polylactide-coated implant composed of a biocorrodible magnesium alloy

Номер: US20120035716A1

Автор: Alexander Borck, Bjoern Klocke

Принадлежит: BIOTRONIK AG

Some invention embodiments relate to an implant having a base body composed of a biocorrodible magnesium alloy and a polylactide coating. The implant is characterized in that the coating contains seed crystals and/or lipophilic substances as additives.

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Номер записи: 7

09-02-2012 дата публикации

Intravitreous self adaptive stent

Номер: US20120035738A1

Автор: Rongping Dai

Принадлежит: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Disclosed herein are devices, methods and kits for a stent for treating an eye, comprising a flexible material, wherein the stent is self adaptive to a dimension of a vitreous cavity in the eye.

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Номер записи: 8

23-02-2012 дата публикации

Forced deployment sequence handle assembly with independent actuating mechanism

Номер: US20120046652A1

Автор: Justin W. Sokel

Принадлежит: WL Gore and Associates Inc

A handle assembly for use in the deployment of a medical device via a plurality of deployment lines that extend through a catheter. The handle assembly includes a plurality of removable members for deployment or actuation of the medical device. The handle assembly also includes an actuating mechanism for displacing a wire extending through the catheter for actuating the medical device independently of the plurality of removable members.

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Номер записи: 9

23-02-2012 дата публикации

Graft Systems Having Filling Structures Supported by Scaffolds and Methods for Their Use

Номер: US20120046684A1

Автор: Amy Lee, Gwendolyn A. Watanabe, Michael A. Evans, Steven L. Herbowy

Принадлежит: Endologix LLC

Aneurysms are treated by filling at least one double-walled filling structure with a curable medium within the aneurysm. The filling structures may be delivered over balloon deployment mechanisms in order to shape and open tubular lumens therethrough. Scaffolds are placed into the tubular lumens in order to help maintain the shape, anchor the filling structures in place, and provide improved blood flow transition into and out of the tubular lumens.

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Номер записи: 10

15-03-2012 дата публикации

Endovascular aneurysm repair system

Номер: US20120065661A1

Автор: Lee Bolduc

Принадлежит: Aptus Endosystems Inc

Method and apparatus for implanting radially expandable prostheses in the body lumens rely on tacking or anchoring of the prostheses with separately introduced fasteners. The prostheses may be self-expanding or balloon expandable. After initial placement, a fastener applier system is introduced within the expanded prostheses to deploy a plurality of fasteners at least one prosthesis end, usually as each end of the prosthesis. The fasteners are usually helical fasteners which are delivered from a helical track in the fastener applier by rotation with a rotator wire. The fasteners will be applied singly, typically in circumferentially spaced-apart patterns about the interior of each end of the prosthesis.

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Номер записи: 11

15-03-2012 дата публикации

Intravascular hinge stent

Номер: US20120065723A1

Автор: Joseph Michael Thielen, William Joseph Drasler

Принадлежит: Individual

A balloon or self expandable endoprosthesis formed of a single or multiple joined stent sections. Each section has a node and strut structure extending throughout in order to uncouple expansion forces of the stent to hold a blood vessel outward from crush forces that resist the formation of an oval shape during crush deformation. The hinge can bend in the direction of a uniformly curved surface of the stent but not in the radial direction. The strut can bend in the radial direction but not in the uniformly curved surface of the stent. The widths, lengths, and radial dimensions of the hinges and struts provide a balloon-expandable hinge stent that is non-crushable. For a self-expanding stent the hinge and strut dimensions provide expansion forces that are controlled independently from crush forces. Expansion properties are determined by the hinge dimensions and crush properties are determined independently by strut dimensions.

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Номер записи: 12

22-03-2012 дата публикации

Stent With Hollow Drug-Eluting Elements

Номер: US20120071961A1

Автор: Ryan Bienvenu

Принадлежит: Medtronic Vascular Inc

A stent includes a plurality of cylindrical elements joined along a common longitudinal axis to form a tube. The cylindrical elements include struts joined by crowns. Hollow, drug-eluting elements are disposed between adjacent cylindrical elements and connect adjacent cylindrical elements to each other. A therapeutic substance fills the lumen of the drug-eluting elements, and openings in the walls of the drug-eluting elements allow elution of therapeutic substance from the lumen for treatment of a vessel.

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Номер записи: 13

05-04-2012 дата публикации

External scaffolds for expanding strictures in tubular organs and their use

Номер: US20120083819A1

Автор: Frank Wang, Tzu Hsin Feng

Принадлежит: Individual

External scaffolds for expanding a stricture in the lumen of a tubular structure or organ in a mammal are disclosed herein. A method for expanding a stricture in the lumen of a tubular structure or organ in a mammal using the above external scaffolds is also disclosed.

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Номер записи: 14

12-04-2012 дата публикации

Hydrogel jacketed stents

Номер: US20120089218A1

Автор: Peter S. Dardi

Принадлежит: Individual

Hydrogel jacketed stents provide the ability to fill in the stent frame in vivo to at least partially cover the interior of the surface of the stent following deployment while having the convenience of attaching the jacket to the exterior of the stent. The hydrogel can be pleated and/or folder over the exterior of the stent to provide for extension of the stent without damaging the hydrogel. The hydrogel sheet can be secured at one or more points along the circumference to associate the sheet of hydrogel with the exterior surface of the stent frame. The stent can be conveniently delivered using similar technology as conventional stents if desired. The hydrogel can provide for drug delivery if desired.

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Номер записи: 15

19-04-2012 дата публикации

Method To Minimize Chain Scission And Monomer Generation In Processing of Poly(L-Lactide) Stent

Номер: US20120091633A1

Автор: James Oberhauser, Yunbing Wang

Принадлежит: Abbott Cardiovascular Systems Inc

Methods of fabricating an implantable medical devices such as stents made from biodegradable polymers are disclosed that reduce or minimize chain scission and monomer generation during processing steps. The method includes processing a poly(L-lactide) resin having an number average molecular weight between 150 to 200 kD in an extruder in a molten state. A poly(L-lactide) tube is formed from the processed resin and a stent is fabricated from the tube. The number average molecular weight of the poly(L-lactide) of the stent after sterilization is 70 to 100 kD.

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Номер записи: 16

19-04-2012 дата публикации

Modular grafting system and method

Номер: US20120095547A1

Автор: Timothy A.M. Chuter

Принадлежит: Endovascular Technologies Inc

A system and method for treating and repairing complex anatomy characterized by a plurality of vessel portions oriented at various angles relative to each other. The system including a graft device that is capable of being assembled in situ and has associated therewith a method that avoids the cessation of blood flow to vital organs. A delivery catheter system and various graft supporting, mating and anchoring structures are additionally included.

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Номер записи: 17

26-04-2012 дата публикации

Adjustable socket system

Номер: US20120101597A1

Автор: Andrew BACHE

Принадлежит: OSSUR HF

An adjustable socket system is configured to accommodate a residual limb. The adjustable socket system has first and second opposed sides and includes a rigid first component arranged along the first side of the socket. An adjustable second component has a plurality of interconnected vertebrae elements connected to the first component and is arranged along the second side of the socket system. The adjustable prosthetic socket also has a base connector secured to the distal end area of the first component.

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Номер записи: 18

03-05-2012 дата публикации

Modular vascular prosthesis and methods of use

Номер: US20120102708A1

Автор: David P. Strauss, Duane DeMore, Michael R. Bialas, Rainer Bregulla, Robert Barbier

Принадлежит: Abbott Laboratories Vascular Enterprises Ltd

The present invention relates a vascular prosthesis and related assembly methods that includes a plurality of modular segments inter-engaged by flexible, and preferably lockable, inter-engageable elements forming joints or other connector areas. The segments may have a number of different mechanical properties and may be assembled by the clinician, through mechanical or chemical joining, to customize the prosthesis for a specific patient or application.

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Номер записи: 19

03-05-2012 дата публикации

Methods and compositions involving (s)-bucindolol

Номер: US20120108617A1

Автор: Jonathan D. Port, Michael R. Bristow

Принадлежит: Arca Biopharma Inc

Disclosed is bucindolol substantially free of its R-stereoisomer. Also disclosed are pharmaceutical compositions that include bucindolol substantially free of its R-stereoisomer or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier. Also disclosed are methods of treating a patient that involve administering to the patient a therapeutically effective amount of a composition of the present invention. Formula (I).

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Номер записи: 20

10-05-2012 дата публикации

Stent delivery system

Номер: US20120116493A1

Автор: Kinya Harada

Принадлежит: Terumo Corp

A stent delivery system includes a distal-side tube, a proximal-side tube, a fixing tube, a stent containing tubular member, a stent in the stent containing tubular member, and a pulling wire for moving the stent containing tubular member to the proximal side. The distal-side tube includes a distal-side priming slit provided in a side wall in proximity to a stent proximal end lock section and a proximal-side priming slit provided in a side wall on the proximal side of the distal-side tube. The slits are opened by injecting liquid, with the distal opening or the rear end opening of a guide wire lumen of the distal-side tube closed.

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Номер записи: 21

10-05-2012 дата публикации

Coated medical devices and methods

Номер: US20120116503A1

Автор: David D. Grewe, Keith Milner, Kenneth Haselby

Принадлежит: Med Inst LLC

The invention relates to medical device systems that include a delivery instrument comprising a sheath having an abluminal surface and a luminal surface; a radially-expandable frame disposed at least partially within the sheath, the frame having an abluminal surface at least partially in contact with the luminal surface of the sheath, and a luminal surface defining a sub-stantially cylindrical lumen; and a fine powder coating disposed on at least one of the abluminal surface of the frame and the luminal surface of the sheath. The invention also relates to methods of manufacturing, loading, and delivering the coated medical devices.

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Номер записи: 22

10-05-2012 дата публикации

Temporary protective gastrointestinal device

Номер: US20120116528A1

Автор: Ninh T. Nguyen

Принадлежит: Endoshield Inc

Disclosed is an intraluminal gastrointestinal (GI) device that is placed at the time of surgery to protect a freshly constructed GI anastomosis, GI staple-line, or the like. For the esophagus and stomach, the device covers the esophagus, stomach, and anastomosis/staple-line. For the pancreas or biliary duct, the device covers the biliary duct, pancreatic duct, and small bowel. For the colon and rectum, the device is a self expanding protective barrier that covers the anal canal, the anus, and the colon or rectum, approximately 18 cm proximal to the anus. These devices provide a waterproof barrier between the gastrointestinal content and the mucosa of the GI tract and the newly constructed anastomosis. Additionally, the design of the device is made to prevent migration within the gastrointestinal tract and facilitate removal of the device.

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Номер записи: 23

10-05-2012 дата публикации

Custom-fitted prosthetic socket devices and methods for producing same

Номер: US20120116539A1

Автор: Peter Armstrong, Wayne Armstrong

Принадлежит: Peter Armstrong, Wayne Armstrong

Methods of producing a custom-fitted prosthetic socket device for a residual limb include covering the distal end thereof with a liner, positioning the covered end within a socket cup to maintain a spaced relationship between the exterior of the liner and the interior of the socket cup, introducing an expandable, hardenable filler material into the socket cup, expanding the material to fill the volume between the liner and the socket cup, hardening the material, and removing the socket cup, hardened filler material, and liner, from the residual limb. Some methods include a filler material that hardens into a flexible solid foam cushioning layer which may optionally form a bond between the socket cup and the liner, embedding the liner in the cushioning layer. Some methods include selecting a socket cup from a plurality of sized socket cups, and/or providing the plurality of sized socket cups.

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Номер записи: 24

17-05-2012 дата публикации

Tubular silk compositions and methods of use thereof

Номер: US20120123519A1

Автор: Christopher M. Cannizzaro, David L. Kaplan, Gordana Vunjak-Novakovic, Michael L. Lovett, Xianyan Wang

Принадлежит: Massachusetts Institute of Technology, TUFTS UNIVERSITY

Described are tubular silk fibroin compositions and methods for their manufacture and use. Tubular compositions as described herein can be produced in a range of high burst strengths, can easily be made in a range of inner diameters, can be derivatized with functional moieties, and can be produced in a range of permeabilities suitable for particularized uses. In one aspect, the tubular compositions can be used in the repair or replacement of damaged or diseased blood vessels, including, but not limited to vessels smaller than about 6 mm.

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Номер записи: 25

17-05-2012 дата публикации

Blood-flow tubing

Номер: US20120123520A1

Автор: John Bruce Cameron Dick, John Graeme Houston, Peter Stonebridge

Принадлежит: Tayside University Hospitals NHS Trust

An artificial or modified natural blood flow tubing has a helical-flow inducer to induce helical flow in such a fashion as to eliminate or reduce turbulence. One inducer is a tubular stent of expansible mesh having a helical vane.

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Номер записи: 26

24-05-2012 дата публикации

Method for producing a small thin-walled tube from a magnesium alloy

Номер: US20120125070A1

Автор: Alois Birgmann, Maria Kuehlein, Martin Brandecker, Thomas Waltenberger

Принадлежит: LKR LEICHTMETALLKOMPETENZZENTRUM RANSHOFEN GMBH

The invention relates to a method for producing a small thin-walled tube for a medical application or for a medical product, in particular for a stent, wherein a blank of an in particular bioresorbable magnesium alloy is deformed to produce a small tube, after which the small tube is used for medical purposes or from which the medical product, such as a stent, can be made. In order to be able to produce the small tube in one step and with high precision, it is provided according to the invention that a male die ( 2 ) with a base body ( 3 ) and a mandrel ( 4 ) tapered relative to the base body ( 3 ) and the blank is provided with a blind hole or an opening, wherein a diameter of the blind hole or the opening of the blank is equal to or greater than an outer diameter of the mandrel ( 4 ), after which the blank with inserted mandrel ( 4 ) with the male die ( 2 ) is pressed forwards at least in part through a female die ( 5 ) with a receiving region ( 6 ) and a contouring region ( 7 ), wherein the contouring region ( 7 ) has a free diameter, which is larger than the outer diameter of the mandrel ( 4 ), but smaller than an outer diameter of the blank, in order to form the small tube.

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Номер записи: 27

24-05-2012 дата публикации

Devices and methods for in situ fenestration of a stent-graft at the site of a branch vessel

Номер: US20120130478A1

Автор: Edward E. Shaw

Принадлежит: WL Gore and Associates Inc

The present disclosure includes a stent-graft comprising a first portion that is configured to engage a vessel wall, a second portion that is configured not to engage the vessel wall, and a perfusion window that is configured to permit blood flow. The stent-graft may further comprise a transition portion between the first portion and the second portion, and the perfusion window may be formed in the first portion, the second portion, and/or the transition portion. In a variety of embodiments, one of the first and the second portion may have a smaller diameter than the other. Similarly, in a variety of embodiments, the transition portion may be frustoconically shaped.

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Номер записи: 28

31-05-2012 дата публикации

Stent Graft System

Номер: US20120136431A1

Автор: Wei-Hui Chen

Принадлежит: Individual

The stent graft system in accordance with the present invention has a trunk, a left subclavian tube, a left common carotid tube and a brachiocephalic tube. The trunk is tubular and expandable and has a descending end, an ascending end, a left subclavian mount, a left common carotid mount and a brachiocephalic mount, for receiving the aforementioned branch tubes that are elastic and self-expandable for respectively connecting the left subclavian artery, the left common carotid artery and the brachiocephalic artery to the trunk. With the above-described structure, the present invention allows fast determination of a suitable trunk and branch tubes for a patient and allows a medical institute to prepare compatible branch tubes and trunks for a composite stent graft system instead of numerous stent grafts of various combinations of differently sized tubular bodies and branches, wherein the former requires significantly less warehousing cost than the latter.

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Номер записи: 29

07-06-2012 дата публикации

Magnesium-Based Absorbable Implants

Номер: US20120143227A1

Автор: Ioannis Pandelidis, Mark Steckel

Принадлежит: Zorion Medical Inc

A bioabsorbable implant including an elongated metallic element comprising an alloy of more than about 70% by weight magnesium and about 2-20% by weight lithium, substantially free of rare earth metals. An implantable tissue filler includes a particulate material suspended in a carrier, comprising more than about 70% by weight magnesium and about 2-20% by weight lithium, substantially free of rare earth metals. A bioabsorbable implant includes an elongated metallic element having a core and at least two layers of alternating compositions of magnesium, iron, and alloys thereof. A bioabsorbable implant includes at least three wires including magnesium and defining a cylindrical sheath surrounding at least one core wire including iron. A bioabsorbable implant includes a plurality of intertwined magnesium alloy wires defining a strand, with an Fe-rich layer formed by vapor, chemical and/or electro-deposition defined on a surface of at least one of the wires.

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Номер записи: 30

07-06-2012 дата публикации

Vacuum prosthesis with force sensing member

Номер: US20120143351A1

Автор: Michael E. Tompkins

Принадлежит: Hanger Orthopedic Group Inc

A prosthetic device includes a socket assembly defining a cavity and configured to receive a portion of a residual limb of a user within the cavity, a force sensing member configured to detect forces applied to the residual limb at a plurality of locations about the portion of the residual limb and generate signals based on the detected force, a vacuum system in fluid communication with the socket and configured to control an amount of vacuum applied to the cavity, and a controller coupled to the force sensing member and the vacuum system. The controller is configured to receive the signals from the force sensing member and control operation of the vacuum system during use of the prosthetic device by the user based at least in part on the signals received from the force sensing member.

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Номер записи: 31

14-06-2012 дата публикации

Apparatus for attaching radiopaque markers to a stent

Номер: US20120144663A1

Автор: Patrick P. Wu

Принадлежит: Abbott Cardiovascular Systems Inc

A mandrel for supporting a stent and rollers for pressing a radiopaque marker into a stent are disclosed. The mandrel can have a forward portion for carrying the stent and a rear portion for urging the stent forward portion into a gap between the rollers. The mandrel may be pushed or pulled into the gap, which is sized to allow the rollers to press the marker into engagement with the stent. Prior to moving the mandrel into the gap, the marker may be placed on a surface of the stent or partially inside a recess in the stent. Several markers can be efficiently and uniformly pressed onto the stent by moving the mandrel into the gap in one continuous movement in an axial or lateral direction. Markers can also be pressed onto the stent by placing the stent in the gap and rotating the stent about its central axis.

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Номер записи: 32

21-06-2012 дата публикации

Method for attaching radiopaque markers to a stent

Номер: US20120151744A1

Автор: Patrick P. Wu

Принадлежит: Abbott Cardiovascular Systems Inc

A mandrel for supporting a stent and rollers for pressing a radiopaque marker into a stent are disclosed. The mandrel can have a forward portion for carrying the stent and a rear portion for urging the stent forward portion into a gap between the rollers. The mandrel may be pushed or pulled into the gap, which is sized to allow the rollers to press the marker into engagement with the stent. Prior to moving the mandrel into the gap, the marker may be placed on a surface of the stent or partially inside a recess in the stent. Several markers can be efficiently and uniformly pressed onto the stent by moving the mandrel into the gap in one continuous movement in an axial or lateral direction. Markers can also be pressed onto the stent by placing the stent in the gap and rotating the stent about its central axis.

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Номер записи: 33

05-07-2012 дата публикации

Progenitor endothelial cell capturing with a drug eluting implantable medical device

Номер: US20120172970A1

Автор: Margaret Yoklavich, Robert John Cottone, Jr., Sherry Parker

Принадлежит: Orbus Medical Technologies Inc

A medical device for implantation into vessels or luminal structures within the body is provided, which stimulates positive blood vessel remodeling. The medical device, such as a stent and a synthetic graft, is provided with a coating with a pharmaceutical composition containing a controlled-release matrix and one or more pharmaceutical substances for direct delivery of drugs to surrounding tissues. The coating on the medical device further comprises one or more barrier layers, and a ligand such as a peptide, an antibody or a small molecule for capturing progenitor endothelial cells in the blood contacting surface of the device for restoring an endothelium at the site of injury. In particular, the drug-coated stents are for use, for example, in balloon angioplasty procedures for preventing or inhibiting restenosis.

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Номер записи: 34

05-07-2012 дата публикации

Dynamically Activated Variable Response Socket with Hydraulic Pump

Номер: US20120173000A1

Автор: Carl A. Caspers

Принадлежит: CARL CASPERS CONSULTING LLC

An articulating prosthetic foot is used for a prosthetic or orthotic artificial limb for amputees having a residual limb. The artificial limb has a pylon and a socket for receiving the residual limb and a vacuum pump connected to the socket. The articulating foot articulates on the pylon and has a hydraulic pump. The hydraulic pump is driven by the articulating motion of the foot and drives the vacuum pump.

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Номер записи: 35

12-07-2012 дата публикации

Structural hydrogel polymer device

Номер: US20120178874A1

Автор: Scott M. Epstein

Принадлежит: Individual

The present invention relates generally a manufacturing process which results in a completely hydrogel polymer device that maintains lumen patency which allows for numerous applications. Catheters and stents are particular examples, and their composition, mechanical characteristics, and the significantly unique ability to conduct and allow fluids to pass from one end to the other without physiological rejection, inflammation, or manifestation of complications due to implant or otherwise undesirable outcomes when used for ambulatory and or therapeutic interventions is the purpose of the invention.

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Номер записи: 36

19-07-2012 дата публикации

Polymer coating comprising 2- methoxyethyl acrylate units synthesized by surface-initiated atom transfer radical polymerization

Номер: US20120184029A1

Автор: Charlotte Juel, Katja Jankova Atanasova, Søren Hvilsted

Принадлежит: Danmarks Tekniskie Universitet

The present invention relates to preparation of a polymer coating comprising or consisting of polymer chains comprising or consisting of units of 2-methoxyethyl acrylate synthesized by Surface-Initiated Atom Transfer Radical Polymerization (SI ATRP) such as ARGET SI ATRP or AGET SI ATRP and uses of said polymer coating.

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Номер записи: 37

19-07-2012 дата публикации

Anti-obesity devices

Номер: US20120184967A1

Автор: Andy H. Levine, David A. Melanson, John C. Meade

Принадлежит: GI Dynamics Inc

Method and apparatus for limiting absorption of food products in specific parts of the digestive system is presented. A gastrointestinal implant device is anchored in the pyloric portion of the gastrointestinal system and extends beyond the ligament of Treitz. All food exiting the stomach is funneled through the device. The gastrointestinal device includes an anchor for anchoring the device in the pyloric portion and a flexible sleeve that extents into the duodenum. The anchor is collapsible for endoscopic delivery and removal.

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Номер записи: 38

26-07-2012 дата публикации

Joined Inflation Portions for Bifurcation Catheter

Номер: US20120186064A1

Автор: Daryl L. Martin, Richard A. Noddin

Принадлежит: Boston Scientific Scimed Inc

An example multi-lumen member forming dual inflation portions of a catheter assembly for treating bifurcated vessels includes a main tube defining a main lumen and a main inflation portion. The member includes a side tube defining a side lumen and a side inflation portion, the side tube extending along at least a first length of the main tube. The member also includes a portion extending along the first length of the main tube and coupling the main tube to the side tube to form a dual lumen configuration.

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Номер записи: 39

26-07-2012 дата публикации

Biodegradable endoprostheses and methods for their fabrication

Номер: US20120187606A1

Автор: John Yan, Vinayak Bhat, Xiaoxia Zheng

Принадлежит: Elixir Medical Corp

Biodegradable endoprostheses are formed from amorphous polymers having desirable biodegradation characteristics. The strength of such amorphous polymers is enhanced by annealing to increase crystallinity without substantially increasing the biodegradation time.

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Номер записи: 40

02-08-2012 дата публикации

Stretch resistant therapeutic device

Номер: US20120197286A1

Автор: Eric Leopold, Peter Wilson, Rupesh K. Desai

Принадлежит: Micrus Corp

A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.

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Номер записи: 41

09-08-2012 дата публикации

Intralumenally-implantable frames

Номер: US20120203327A1

Автор: Andrew K. Hoffa, Brian C. Case, Darin G. Schaeffer, Jacob A. Flagle, Michael L. Garrison

Принадлежит: Cook Medical Technologies LLC

Implantable frames for use in body passages are provided herein. The implantable frames can include a plurality of hoop members joined by a plurality of longitudinal connecting members to form a tubular frame defining a cylindrical lumen. The plurality of longitudinal connecting members may include first and second longitudinal connecting members joining a first hoop member to a second hoop member such that the first and second longitudinal connecting members extend across an entire space separating the first and second hoop members.

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Номер записи: 42

13-09-2012 дата публикации

Methods for fabricating polymer-bioceramic composite implantable medical devices

Номер: US20120228810A1

Автор: Bin Huang, David C. Gale

Принадлежит: Advanced Cardiovascular Systems Inc

Methods relating to polymer-bioceramic composite implantable medical devices are disclosed.

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Номер записи: 43

13-09-2012 дата публикации

Stent fabrication via tubular casting processes

Номер: US20120232643A1

Автор: Alfred N. K. CHIA, Kamal Ramzipoor, Liwei Wang

Принадлежит: Amaranth Medical Pte

Tubular casting processes, such as dip-coating, may be used to form substrates from polymeric solutions which may be used to fabricate implantable devices such as stents. The polymeric substrates may have multiple layers which retain the inherent properties of their starting materials and which are sufficiently ductile to prevent brittle fracture. Parameters such as the number of times the mandrel is immersed, the duration of time of each immersion within the solution, as well as the delay time between each immersion or the drying or curing time between dips and withdrawal rates of the mandrel from the solution may each be controlled to result in the desired mechanical characteristics. Additional post-processing may also be utilized to further increase strength of the substrate or to alter its shape.

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Номер записи: 44

20-09-2012 дата публикации

Defferential dilation stent and method of use

Номер: US20120239137A1

Автор: Kumar G. Jambunathan, Richard R. Heuser

Принадлежит: PQ Bypass Inc

Embodiments herein provide differential dilation stents for use in percutaneous interventions, such as transluminal bypass procedures. In some embodiments, the stents may be used in the process of creating an arteriovenous (AV) fistula during a percutaneous bypass procedure, and such stents may have two or more specialized regions that are configured to adopt a predetermined diameter, shape, and/or tensile strength upon insertion in order to suit the needs of the vessel or procedure. The disclosed stents may be used for creating and/or maintaining an arterial/venous fistula for bypass of an occlusion in a cardiac artery using a cardiac vein, or the femoral artery, for example using the tibial or popliteal vein.

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Номер записи: 45

11-10-2012 дата публикации

Intraluminal scaffold system and use thereof

Номер: US20120259399A1

Автор: Kevin J. Ehrenreich, Randolf Von Oepen

Принадлежит: ABBOTT LABORATORIES

Intraluminal scaffold assembly implantable in a body lumen of a patient to manipulate a valve of the lumen is provided. The intraluminal scaffold assembly includes an intraluminal scaffold, an elongated core member coupled with the intraluminal scaffold having a length sufficient to traverse a valve in a body lumen with the intraluminal scaffold positioned proximate the valve. The intraluminal scaffold assembly can further include one or more additional intraluminal scaffolds, a weighted element or an active element that is coupled with the elongated core member. A system including a delivery system and the intraluminal scaffold assembly, as well as methods of delivering the intraluminal scaffold assembly and using the intraluminal scaffold assembly to manipulate a valve in a body lumen, is also provided.

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Номер записи: 46

11-10-2012 дата публикации

Flexible intraluminal scaffold

Номер: US20120259400A1

Автор: Kevin J. Ehrenreich, Randolf Von Oepen

Принадлежит: ABBOTT LABORATORIES

Expandable intraluminal scaffold defining a longitudinal axis is provided, wherein the scaffold includes at least two filaments extending from a head portion disposed along the longitudinal axis at a first longitudinal end, each of the at least two filaments including a free end portion at a second longitudinal end opposite the head portion. The at least two filaments converge toward each other at a juncture disposed proximate the longitudinal axis between the first longitudinal end and the second longitudinal end. A system including a delivery system and the intraluminal scaffold, as well as a method of delivering the scaffold, is also provided.

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Номер записи: 47

25-10-2012 дата публикации

Graft Devices and Methods of Use

Номер: US20120271405A1

Автор: J. Christopher Flaherty, Jon Mcgrath, Lorenzo Soletti, Mohammed S. El-Kurdi

Принадлежит: Neograft Technologies Inc

A tubular graft device is provided comprising a tubular member and a fiber matrix of one or more polymers about a circumference of the tubular member. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a harvested saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft and connecting the graft between a first body space and a second body space, such as the aorta and a location on an occluded coronary artery, distal to the occlusion.

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Номер записи: 48

01-11-2012 дата публикации

Soluble coating comprising polyelectrolyte with hydrophobic counterions

Номер: US20120276185A1

Автор: Lothar W. Kleiner, Mikael O. Trollsas, Syed F.A. Hossainy

Принадлежит: Individual

The present invention provides an implantable device having a biosoluble coating comprising a polyelectrolyte and a counterion and the methods of making and using the same.

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Номер записи: 49

08-11-2012 дата публикации

Helical hybrid stent

Номер: US20120283817A1

Автор: Jacob Richter

Принадлежит: Medinol Ltd

An expandable helical stent is provided, wherein the stent may be formed of an amorphous metal alloy or other non-amorphous metal with a securement. The stent is formed from flat or tubular metal in a helical coiled structure which has an undulating pattern. The main stent component may be formed of a single helically coiled component. Alternatively, a plurality of helically coiled ribbons may be used to form a stent heterogeneous in design, material, or other characteristic particular to that stent. The helical tubular structure may be secured with a securement, such as a weld, interlock or a polymer, to maintain the helical coils in a tubular configuration. The helical coils of the main stent component may be spaced apart or nestled to each other to maintain the tubular shape of the helically coiled stent and prevent the polymer layer from sagging at any point between cycles of the coils.

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Номер записи: 50

08-11-2012 дата публикации

Antithrombotic and anti-restenotic drug eluting stent

Номер: US20120283822A1

Автор: Jonathon Z. Zhao, JR.

Принадлежит: Cordis Corp

An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. A plurality of different beneficial agents may be loaded into different openings within the struts for delivery to the tissue. For treatment of conditions such as restenosis, different beneficial agents are loaded into different openings in the device to address different biological processes involved in restenosis and are delivered at different release kinetics matched to the biological process treated. The different beneficial agents may also be used to address different diseases, such as restenosis and acute myocardial infarction from the same drug delivery device. In addition, anti-thrombotic agents may be affixed to at least a portion of the surfaces of the medical device for the prevention of sub-acute thrombosis.

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Номер записи: 51

15-11-2012 дата публикации

Electrochemical formation of foil-shaped stent struts

Номер: US20120285836A1

Автор: Randolf Von Oepen

Принадлежит: Abbott Cardiovascular Systems Inc

An apparatus and method for electrochemically treating the struts of an intravascular stent is disclosed. An intravascular stent is mounted in a chamber and is electrochemically treated in order to remove a portion of the stent struts in order to form an airfoil shape. The airfoil-shaped stent struts will reduce turbulent blood flow in the vasculature in which the stent is implanted thereby improving clinical outcome.

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Номер записи: 52

15-11-2012 дата публикации

Vascular remodeling device

Номер: US20120290067A1

Автор: Anh Cam, Jianlu Ma, Michael Louis LOSORDO, Xiaoling Zhao

Принадлежит: TYCO HEALTHCARE GROUP LP

Described herein are flexible implantable devices or stents that can conform to the shape of vessels of the neurovasculature. In some embodiments, the devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. In some embodiments, a vascular remodeling device includes a first section and a protruding section. During deployment, the device expands from a compressed configuration to an expanded configuration. The first section anchors the device in an afferent vessel and/or in an efferent vessel of a bifurcation and the protruding section is positioned in the junction of the bifurcation having an aneurysm and across the neck of the aneurysm or at least partially within the aneurysm.

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Номер записи: 53

15-11-2012 дата публикации

Paraplegia prevention valve for stent grafts

Номер: US20120290069A1

Автор: David Ernest Hartley, Krasnodar Ivancev, Piotr Miroslaw Kasprzak

Принадлежит: Cook Medical Technologies LLC

A stent graft defining a main lumen bounded by a wall of graft material is disclosed. The stent graft has a valve portion between proximal and distal portions. The valve portion is formed by a wall portion having a part-circumferential double layer portion comprising an inner underlap portion and an outer overlap portion, the double layer portion forming a passageway parallel to the main lumen. The passageway has an entrance mouth and an exit mouth. The passageway has an open condition where the underlap and overlap portions are spaced apart to form a vent lumen. The wall portion is broken by a narrow cut. The cut is openable by relative radial movement between its edges. This allows re-perfusion of an aneurism and perfusion of blood from within the lumen out towards blood vessels such as intercostals and can assist in minimising the chance of paraplegia.

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Номер записи: 54

15-11-2012 дата публикации

Implantable medical device having enhanced endothelial migration features and methods of making the same

Номер: US20120290074A1

Автор: Julio C. Palmaz

Принадлежит: Palmaz Scientific Inc

An implantable medical device having enhanced endothelial migration features, generally comprises: a structural member including a leading edge and a trailing edge interconnected by a third surface region, the leading edge including a second surface region in a generally curvilinear cross-section, and the trailing edge including a fourth surface region in a generally curvilinear cross-section, whereby blood flow over the second surface region generate shear stress at the second surface region without an eddy region in the second surface region.

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Номер записи: 55

22-11-2012 дата публикации

Method and device for loading medical appliance with medicaments and/or polymers

Номер: US20120294499A1

Автор: Bo YI, Changsheng Wu, Jie Zhang, Qiyi Luo, Zhirong Tang

Принадлежит: Microport Medical Shanghai Co Ltd

A method and a device for loading a medical appliance with a medicament and/or polymer includes capturing images of a plurality of grooves or holes of the medical appliance using an image capturing device; performing digital image processing on the image of each of the grooves or holes to obtain a pattern of each of the grooves or holes; calculating a central position of the pattern of each of the grooves or holes, and determining a loading position of each of the grooves or holes based on the central position; and adjusting a relative position between a loading device and the medical appliance to align an outlet of the loading device with the loading position of the medical appliance, and loading each of the grooves or holes with the medicament and/or polymer. The method and device can load the medical appliance with the medicament and/or polymer fast and efficiently.

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Номер записи: 56

22-11-2012 дата публикации

Methods and systems for performing vascular reconstruction

Номер: US20120296408A1

Автор: Donald K. Jones, Vladimir Mitelberg

Принадлежит: Individual

Devices, systems and methods are provided for performing intra-lumenal medical procedures in a desired area of the body. Stents, stent delivery devices and methods of performing medical procedures to redirect and or re-establish the intravascular flow of blood are provided for the treatment of hemorrhagic and ischemic disease states.

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Номер записи: 57

22-11-2012 дата публикации

Thoracic aorta stent graft

Номер: US20120296414A1

Автор: David Ernest Hartley

Принадлежит: Cook Medical Technologies LLC, William A Cook Australia Pty Ltd

A stent graft for placement in the thoracic arch of a patient has a tubular body defining a main lumen therethrough, a plurality of zig zag stents along the tubular body, each of the stents comprising a plurality of struts and bends, the bends being between adjacent struts. At least a first stent and an adjacent second stent having at least a pair of adjacent bends on the first stent aligned with an adjacent pair of bends on the second stent, whereby a first pair of adjacent struts of the first stent and a second pair of adjacent struts of the second adjacent stent together define a diamond shape region. A recess is within the diamond shaped region with the recess extending into the lumen of the tubular body. A fenestration extending into the tubular body within the recess in the diamond shaped region and a graft tube leading from the fenestration into the main lumen. There can be one, two or three diamond shaped regions, recesses, fenestrations and graft tubes Proximally of the or each diamond shaped region the tubular body has a first diameter, distally of the diamond shaped region the tubular body has a second diameter and in the region of the tubular body around the diamond shaped region the tubular body has a third diameter, the first diameter being greater than the second diameter and both the first and second diameter being greater than the third diameter whereby a central region is defined which will allow circumferential blood flow during an operation out of the graft tube into the recess and then into the central region.

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Номер записи: 58

06-12-2012 дата публикации

Gastrointestinal implant device and delivery system therefor

Номер: US20120310138A1

Автор: Niall Behan

Принадлежит: Vysera Biomedical Ltd

A delivery system comprises a delivery catheter with a distal capsule which contains a scaffold, a valve and a sleeve in the retracted configuration. The delivery system includes a proximal expandable element provided by an inflatable proximal balloon and a distal expandable element provided by a distal balloon. The proximal balloon provides a temporary seal at the proximal side of the valve. The distal balloon provides a temporary distal seal between a distal olive and a distal end of the sleeve. An inflation fluid is introduced into the sleeve between the proximal and distal balloons the fluid causes the sleeve to expand axially to the expanded deployed configuration. When the sleeve is in the extended deployed configuration the distal balloon is deflated, allowing the olive to detach and travel distally. The rest of the delivery system can then be withdrawn proximally, leaving the implant device in situ.

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Номер записи: 59

13-12-2012 дата публикации

Virtual prototyping and testing for medical device development

Номер: US20120316854A1

Автор: Michael V. Chobotov, Robert G. Whirley

Принадлежит: TriVascular Inc

A system and method of developing better-designed medical devices, particularly cardiovascular stents and endovascular grafts. The system comprises a geometry generator, a mesh generator, a stress/strain/deformation analyzer, and a visualization tool. Using analysis, preferably non-linear analysis, the stress/strain/deformation analyzer determines the predicted stresses, strains, and deformations on the candidate medical device. Such stresses, strains, and deformations may optionally be simulated visually using a visualization tool.

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Номер записи: 60

20-12-2012 дата публикации

Drug delivery system and method of manufacturing thereof

Номер: US20120321707A1

Автор: Richard C. Svrluga, Stephen M. Blinn

Принадлежит: Exogenesis Corp

In one embodiment, a drug delivery system and method provide a member including a combination of a drug substance and a polymer or other material, and an encapsulating layer formed in an outer surface of the member by gas cluster ion beam irradiation of the outer surface of the member, which encapsulating layer is adapted to determine one or more characteristics of the drug delivery system.

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Номер записи: 61

20-12-2012 дата публикации

Paraplegia prevention stent graft

Номер: US20120323303A1

Автор: Krasnodar Ivancev

Принадлежит: Cook Medical Technologies LLC

A stent graft ( 10 ) for deployment into the aorta of a patient has a tubular body ( 12 ) with a proximal portion ( 14 ) of a selected diameter and a portion ( 16 ) of a reduced diameter less than the selected diameter distal of the proximal portion and a tapered portion ( 18 ) extending between the proximal portion and the portion of reduced diameter. Low profile side arms ( 26, 28, 30, 32 ) are provided in the portion of reduced diameter and/or the tapered portion. The side arms are for connection of an arm extension to an aortic branch vessel. A paraplegia prevention vent tube ( 34 ) is provided in fluid communication with the main lumen and open to external of the tubular body in the region defined by the portion of reduced diameter and the tapered portion. The paraplegia prevention vent tube is not intended to be connected to a side branch of the aorta but is intended, and is so constructed and arranged, to provide temporary perfusion to external of the stent graft after deployment of the stent graft into the aorta and is intended, and is so constructed and arranged, to be subsequently blocked.

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Номер записи: 62

20-12-2012 дата публикации

Stent for endoluminal delivery of active principles or agents

Номер: US20120323312A1

Автор: Andrea Grignani, Enrico Pasquino, Giovanni Rolando, Maria Curcio

Принадлежит: Sorin Biomedica Cardio SpA

The present invention provides a stent for implantation at a site within a human or animal body comprising: an expandable body having an inner surface and an outer surface; and treatment agents applied to the outer surface of the expandable body, the treatment agents comprising a combination of Paclitaxel and FK506 or their derivatives or analogues.

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Номер записи: 63

10-01-2013 дата публикации

Stent for connecting adjacent tissues of organs

Номер: US20130012969A1

Автор: Kyong-Min Shin

Принадлежит: Individual

Disclosed herein is a stent for connecting adjacent tissues of the organs of a patient. The stent includes a hollow cylindrical body which is formed by weaving a superelastic shape-memory alloy wire in an overlapping manner such that rhombic openings are formed, and wing parts which are provided by expanding respective opposite ends of the hollow cylindrical body outwards and turning the opposite ends inside out on bent portions. The wing parts face each other so that the wing parts are tensed in a longitudinal direction of the cylindrical body. Thereby, the wing parts can elastically move inwards or outwards with respect to the longitudinal direction to automatically adjust a distance between the wing parts in response to the distance between the adjacent tissues of the organs or thicknesses of walls of the organs, so that the wing parts are put into close contact with the adjacent tissues.

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Номер записи: 64

17-01-2013 дата публикации

Method for fabricating medical devices with porous polymeric structures

Номер: US20130017313A1

Автор: Kumin Yang, Neftali Fernandez

Принадлежит: Abbott Cardiovascular Systems Inc

Medical articles with porous polymeric structures and methods of forming thereof are disclosed. The porous structure can have pores sizes that are nanoporous or greater than nanoporous. The porous structure can be a coating or layer of a medical device such as a stent, stent graft, catheter, or lead for pacemakers or implantable cardioverter defibrillators. Additionally, the body of the medical device can be a porous polymeric structure. The porous structure can be made from bioabsorbable polymers. The porous structures can be formed by contacting a polymer with a supercritical fluid.

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Номер записи: 65

14-02-2013 дата публикации

Method of making polymer-bioceramic composite implantable medical devices

Номер: US20130041065A1

Автор: Bin Huang, David C. Gale, Garth L. Wilkes, Syed Faiyaz Ahmed Hossainy, Vincent J. Gueriguian, Yunbing Wang

Принадлежит: Advanced Cardiovascular Systems Inc

Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed.

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Номер записи: 66

14-02-2013 дата публикации

In vivo sensor and method of making same

Номер: US20130041251A1

Автор: Christopher E. Banas, Christopher T. Boyle, Denes Marton, Steven R. Bailey

Принадлежит: Advanced Bio Prosthetic Surfaces Ltd

Implantable in vivo sensors used to monitor physical, chemical or electrical parameters within a body. The in vivo sensors are integral with an implantable medical device and are responsive to externally or internally applied energy. Upon application of energy, the sensors undergo a phase change in at least part of the material of the device which is then detected external to the body by conventional techniques such as radiography, ultrasound imaging, magnetic resonance imaging, radio frequency imaging or the like. The in vivo sensors of the present invention may be employed to provide volumetric measurements, flow rate measurements, pressure measurements, electrical measurements, biochemical measurements, temperature, measurements, or measure the degree and type of deposits within the lumen of an endoluminal implant, such as a stent or other type of endoluminal conduit. The in vivo sensors may also be used therapeutically to modulate mechanical and/or physical properties of the endoluminal implant in response to the sensed or monitored parameter.

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Номер записи: 67

14-02-2013 дата публикации

Vascular Shield and Delivery System

Номер: US20130041453A1

Автор: Paul M. Consigny

Принадлежит: Abbott Cardiovascular Systems Inc

Devices for providing physical support to vascular regions including vascular regions that may contain an anastomosis region are disclosed. These devices may also deliver therapeutic agents to the vascular region. Methods for using these devices are disclosed, as well.

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Номер записи: 68

14-02-2013 дата публикации

Branch vessel prostheses

Номер: US20130041456A1

Автор: Roy K. Greenberg

Принадлежит: Roy K. Greenberg

The present embodiments provide a branch vessel prosthesis for placement at least partially between a main vessel and a branch vessel of a patient. The branch vessel prosthesis has a graft including a generally tubular body of a biocompatible material. At least one stent is coupled to a proximal region of the graft, and at least one stent is coupled to a distal region of the graft. The proximal region of the graft includes a generally straight configuration in an expanded deployed state that is substantially parallel to a longitudinal axis of a main vessel. The distal region of the graft includes a generally straight configuration in the expanded deployed state that is substantially parallel to a branch vessel. A curvature of a central region varies an angle in which the distal region of the graft is disposed relative to the proximal region.

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Номер записи: 69

21-02-2013 дата публикации

Stented Prosthetic Heart Valves

Номер: US20130046378A1

Автор: Billie J. Millwee, Carol E. Eberhardt, Debra A. Taitague, Janice L. Shay, Mark J. Capps, Mark J. Dolan

Принадлежит: MEDTRONIC INC

A surgical sutureless valve that is attached to a stent frame for delivery to a location in a patient using percutaneous implantation devices and methods.

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Номер записи: 70

28-02-2013 дата публикации

Deformable Lumen Support Devices and Methods of Use

Номер: US20130053943A1

Автор: Andy Edward Denison, Kent C.B. Stalker

Принадлежит: CeloNova Stent Inc

Lumen support devices and methods of their use are provided. A lumen support includes one or more plastically deformable cells having two stable configurations with no stable configurations between the two stable configurations. The lumen support device may be plastically deformed to other stable configurations.

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Номер записи: 71

14-03-2013 дата публикации

Device for loading self-expanding stents

Номер: US20130061463A1

Автор: Dennis Vaughan, Israel James Jessop, Thomas D. Ellsworth

Принадлежит: Cordis Corp

A loading device for self-expanding stents that utilizes a rod with a stop on one end, a compressible sleeve that is slidably mounted on the rod and a compressible member slidably mounted on the rod and configured to increase the diameter of the compressible sleeve when forced against it.

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Номер записи: 72

21-03-2013 дата публикации

COATINGS OF ACRYLAMIDE-BASED COPOLYMERS

Номер: US20130071449A1

Автор: Glauser Thierry, HOSSAINY Syed Faiyaz Ahmed, Trollsas Mikael O.

Принадлежит: Abbott Cardiovascular Systems Inc.

An implantable device including a conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided. 2. The implantable device of claim 1 , wherein the linker comprises succinic anhydride claim 1 , glutaric anhydride claim 1 , dimethyl succinic anhydride claim 1 , methyl glutaric anhydride claim 1 , a thioester claim 1 , a disulfide bond claim 1 , a PLA-oligomer claim 1 , a PLGA-oligomer claim 1 , a PCL-oligomer claim 1 , an ester linkage claim 1 , or an anhydride linkage.3. The implantable device of claim 1 , wherein the linker comprises succinic anhydride claim 1 , glutaric anhydride claim 1 , dimethyl succinic anhydride claim 1 , or methyl glutaric anhydride.4. The implantable device of claim 1 , wherein the linker comprises poly(ethylene glycol) (PEG) claim 1 , an alkyl chain claim 1 , or a peptide sequence.5. The implantable device of claim 4 , wherein the peptide sequence comprises glycine-phenylalinine-leucine-glycine.6. The implantable device of claim 1 , wherein the linker comprises poly(ethylene glycol) (PEG) claim 1 , poly(alkylene oxide) claim 1 , C1-C12 alkyl claim 1 , C1-C12 cycloalkyl claim 1 , or C1-C12 aryl.7. The implantable device of claim 1 , wherein the copolymer is poly[N-(2-hydroxypropyl)methacrylamide-co-methoxyethyl methacrylate] (HPMA-co-MOEMA).8. The implantable device of claim 1 , wherein the copolymer is a random or block copolymer.9. The implantable device of claim 1 , which is a stent.10. The implantable device of claim 1 , wherein the bioactive agent is selected from the group consisting of halofuginone claim 1 , paclitaxel claim 1 , docetaxel claim 1 , estradiol claim 1 , 17-beta-estradiol claim 1 , a nitric oxide donor claim 1 , super oxide dismutase claim 1 , a super oxide dismutase mimic claim 1 , 4-amino-2 claim 1 ,2 claim 1 ,6 claim 1 ,6-tetramethylpiperidine-1-oxyl (4-amino-TEMPO) claim 1 , tacrolimus claim 1 , dexamethasone claim 1 , rapamycin claim 1 , a rapamycin derivative claim 1 , 40-O-(2-hydroxy)ethyl- ...

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Номер записи: 73

21-03-2013 дата публикации

Stent

Номер: US20130073023A1

Автор: Bertrand Olivier, Leask Richard Lawrence, Mongrain Rosaire

Принадлежит:

A stent insertable in a body vessel, the body vessel defining a vessel wall. The stent includes a plurality of struts, the struts defining a substantially elongated stent passageway, the struts being configured, sized and operatively coupled to each other in a manner such that the stent is deformable between a first configuration and a second configuration. In the first configuration, the stent passageway has a first radial dimension and a first longitudinal dimension, and in the second configuration, the stent has a second radial dimension and a second longitudinal dimension, the second radial dimension being at least as large as the first radial dimension and the second longitudinal dimension being larger than the first longitudinal dimension. The stent is able to expand substantially longitudinally with the body vessel as the body vessel grows without reducing in diameter so as to reduce risks of damaging the vessel wall as the body vessel grows. 1. A stent insertable in a body vessel , said body vessel defining a vessel wall , said stent comprising:a plurality of struts, said struts defining a substantially elongated stent passageway, said struts being configured, sized and operatively coupled to each other in a manner such that said stent is deformable-longitudinally and radially between a first configuration and a second configuration;wherein in said first configuration, said stent passageway has a first radial dimension and a first longitudinal dimension and in said second configuration, said stent has a second radial dimension and a second longitudinal dimension;said second radial dimension being larger than said first radial dimension and said second longitudinal dimension being larger than said first longitudinal dimension;wherein, after having been inserted in said body vessel, said stent is able to expand substantially longitudinally and radially with said body vessel as said body vessel grows.2. A stent as defined in claim 1 , wherein said struts define ...

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Номер записи: 74

21-03-2013 дата публикации

Co-BASED ALLOYS FOR BIOMEDICAL APPLICATIONS AND STENT

Номер: US20130073028A1

Автор: CHIBA Akihiko

Принадлежит: SEIKO INSTRUMENTS INC.

A first object of the present invention is to provide Co-based alloys for biomedical applications which are Ni-free, high intensity and high elastic modulus and are suitable for plastic workability. Moreover, a second object of the present invention is to provide Co-based alloys for biomedical applications having X-ray visibility. Furthermore, a third object of the present invention is to provide a stent using the alloys. The Co-based alloys for biomedical applications according to the present invention is configured by adding alloy elements having biocompatibility and an effect of increasing stacking fault energy of the alloys. 1. Co-based alloys for biomedical applications comprising:an alloy element, which has biocompatibility and is effective in increasing stacking fault energy of the corresponding alloys, which is added to Co—Cr—W system alloys.2. The Co-based alloys for biomedical applications according to claim 1 , wherein the alloy element is one type or two types or more selected from a group consisting of Nb claim 1 , Ta and Fe.3. The Co-based alloys for biomedical applications according to claim 1 , wherein the alloy element is Nb and/or Ta.4. The Co-based alloys for biomedical applications according to claim 2 , wherein the alloy element is Nb and/or Ta.5. The Co-based alloys for biomedical applications according to claim 1 , containing Cr: 5% by mass to 30% by mass and W: 5% by mass to 20% by mass.6. The Co-based alloys for biomedical applications according to claim 2 , containing Cr: 5% by mass to 30% by mass and W: 5% by mass to 20% by mass.7. The Co-based alloys for biomedical applications according to claim 3 , containing Cr: 5% by mass to 30% by mass and W: 5% by mass to 20% by mass.8. The Co-based alloys for biomedical applications according to claim 4 , containing Cr: 5% by mass to 30% by mass and W: 5% by mass to 20% by mass.9. The Co-based alloys for biomedical applications according to claim 3 , wherein the addition amount of the alloy element ...

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Номер записи: 75

21-03-2013 дата публикации

STENT WITH IMPROVED END CELL STRUCTURAL MEMBER

Номер: US20130073052A1

Автор: Kim Seoggwan, Swift Richard A.

Принадлежит:

A stent () is provided with an improved structural member () at the end () of the stent structure () to minimize deformation of the stent structure when pushing forces are applied to the end of the stent. The improved structural member is wider than other structural members () in the stent structure. The improved structural member is better able to distribute pushing forces to the other structural members in the stent structure with minimal deformation. 1. A stent , comprisinga series of structural members extending around a circumference from a first end to a second end, said structural members being expandable between a collapsed diameter and an expanded diameter;wherein said structural members forming one of said first and second ends comprise a series of first structural members and a series second structural members, wherein each of said first structural members are circumferentially interconnected by said second structural members;a pushing member attached to an outer end of each of said first structural members; andwherein said first structural members are at least 1.5 times as wide as said second structural members.2. The stent according to claim 1 , wherein said stent is about 5 French or less in diameter.3. The stent according to claim 1 , wherein said stent is between about 4 and about 5 French in diameter.4. The stent according to claim 1 , wherein said first structural members are at least 2.25 times wider than said second structural members.5. The stent according to claim 1 , wherein said stent is self-expanding.6. The stent according to claim 1 , wherein a cross-section of said series of structural members is generally rectangular.7. The stent according to claim 1 , wherein said pushing member is a round eyelet.8. The stent according to claim 1 , wherein each of said pushing members is attached to one of said second structural members on both sides of each of said first structural members.9. The stent according to claim 8 , wherein each of said first ...

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Номер записи: 76

21-03-2013 дата публикации

Implantable Prosthetic Device For Distribution Of Weight On Amputated Limb And Method Of Use With An External Prosthetic Device

Номер: US20130073057A1

Автор: Larry Nelson Smith

Принадлежит: Individual

Embodiments of the invention include an implantable force distribution boot with hydraulic features that mimic the natural hydraulics of a joint. Further embodiments include an exterior prosthetic leg device having intermittent and/or variable electromagnetic features that can engage with magnetic blades on the implantable force distribution boot. In use, the exterior prosthetic leg can be maintained on a residual limb by magnetic force between the implanted blades and the exterior electromagnets. Also disclosed are surgical techniques for preparing a residual limb to better receive and adapt to a prosthetic device. The techniques include an improved surgical method for harvesting a vascularized glabrous skin free flap.

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Номер записи: 77

28-03-2013 дата публикации

Distal detachment mechanisms for vascular devices

Номер: US20130079864A1

Автор: Michael C. Brown, Thomas Boden

Принадлежит: Codman and Shurtleff Inc

A system for delivering an expandable implant into the vasculature of a patient, including an elongated core element having a proximal end accessible exterior to the patient and a distal end including at least one feature for engaging a proximal portion of the implant in a collapsed state. The system further includes an expansion limiter having an inner diameter and a length sufficient to cover the proximal portion of the implant and to retain the proximal portion in the collapsed state, and at least one elongated member having a distal end connected to the expansion limiter and a proximal end accessible exterior to the patient to enable proximal movement of the expansion limiter to release the implant.

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Номер записи: 78

28-03-2013 дата публикации

STENT FOR THE POSITIONING AND ANCHORING OF A VALVULAR PROSTHESIS IN AN IMPLANTATION SITE IN THE HEART OF A PATIENT

Номер: US20130079869A1

Автор: Jung Johannes, Straubinger Helmut

Принадлежит:

The present invention relates to a stet for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient. Specifically, the present invention relates to an expandable stent for an endoprosthesis used in the treatment of a narrowing of a cardiac valve and/or a cardiac valve insufficiency. So as to ensure that no longitudinal displacement of a valvular prosthesis fastened to a stent will occur relative the stent in the implanted state of the stent, even given the peristaltic motion of the heart, the stent according to the invention comprises at least one fastening portion via which the valvular prosthesis is connectable to the stent. The stent further comprises positioning arches and retaining arches, whereby at least one positioning arch is connected to at least one retaining arch via a first connecting web. The stent moreover comprises at least one auxiliary retaining arch which connects the respective arms of the at least one retaining arch connected to the at least one positioning arch. 121-. (canceled)22. A stent , comprising:a lattice skirt, having a plurality of closed cells extending around a circumference of the stent and disposed at a first end of the stent;a plurality of first arches, each having an apex projecting toward the first end of the stent and configured to be disposed within a sinus pocket of a native valve radially outward of a plurality of leaflets of the native valve when the stent is implanted;a first set of retaining arms, wherein respective first ends of each of the retaining arms of the first set are joined to the lattice skirt, and wherein respective second ends of each of the retaining arms of the first set are joined to one another;a second set of retaining arms, wherein respective first ends of each of the retaining arms of the second set are joined to the lattice skirt, and wherein respective second ends of each of the retaining arms of the second set are joined to one another;a first pair of ...

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Номер записи: 79

28-03-2013 дата публикации

Endoluminal prosthesis with steerable branch

Номер: US20130079870A1

Автор: Blayne A. Roeder, Jarin Kratzberg, Matthew S. Huser, Roy K. Greenberg

Принадлежит: CLEVELAND CLINIC FOUNDATION, Cook Medical Technologies LLC

An endoluminal prosthesis may include a tubular main graft body including a sidewall and proximal and distal ends. A first stent may be positioned near the proximal end of the main graft body. A second stent may be positioned adjacent to and distal of the first stent. An opening in the sidewall may be positioned longitudinally between a peak of the first stent and a valley of the second stent. A tubular branch may be disposed in the opening. The branch may include first and second end openings. The branch may be flexibly orientable between a retrograde configuration in which the first end opening is oriented toward the distal end and the second end opening is oriented toward the proximal end and an antegrade configuration in which the first end opening is oriented toward the proximal end and the second end opening is oriented toward the distal end.

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Номер записи: 80

28-03-2013 дата публикации

VASCULAR ELASTANCE

Номер: US20130079871A1

Автор: Little Eric F., Scandurra John, Scorzelli Christopher, Vollmers Karl

Принадлежит: Regents of the University of Minnesota

A device includes a balloon and an interface. The balloon has an outer surface and a central lumen aligned on a longitudinal axis. The balloon is configured to receive a compressible fluid. The interface is coupled to the outer surface and has an external surface configured to bond with a tissue. 1. A device comprising:a balloon having an outer surface and a central lumen aligned on a longitudinal axis, the balloon configured to receive a compressible fluid; andan interface coupled to the outer surface and having an external surface configured to bond with a tissue.2. The device of wherein the balloon has a toroidal shape.3. The device of wherein the balloon includes a plurality of fenestrations.4. The device of wherein the balloon includes a plurality of inflatable elements distributed about the central lumen.5. The device of wherein the inflatable elements are aligned with the longitudinal axis.6. The device of wherein the interface including at least one of a scaffold or stent.7. The device of wherein the interface including a cylindrical sleeve.8. The device of wherein the external surface configured to enable endothelial cell development.9. The device of wherein the interface configured to provide a fluid-tight joint with the tissue.10. A device comprising:a core having a compliant member and a channel, the channel configured to receive a portion of an organ and the compliant member having a volume determined by fluid pressure in the channel; anda frame configured to receive the core an oppose expansion of the core.11. The device of wherein the core includes a cylindrical configuration and a longitudinal joint.12. The device of wherein the frame includes a tubular shell.13. The device of wherein the compliant member includes at least one of foam or a balloon.14. A device comprising:a chamber having an aperture and an impermeable wall, the aperture configured to couple with an organ; anda membrane sealably coupled to the aperture.15. The device of wherein the ...

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Номер записи: 81

04-04-2013 дата публикации

DRUG-IMPREGNATED BIODEGRADABLE STENT AND METHODS OF MAKING THE SAME

Номер: US20130084322A1

Автор: Wu Tim

Принадлежит: Tim Wu

The present invention relates to a drug-impregnated implantable medical device such as stent manufactured from polymers, and more particularly, biodegradable polymers including biodegradable polyesters. The invented medical devices include at least one therapeutic agent impregnated in at least one biodegradable polymer wherein at least a portion of the therapeutic agent in this polymer is crystalline. The device and methods to impregnated one or more therapeutic agents, where each therapeutics agent may be chosen from the following categories: immunosuppressant agents, anti-neoplastic agents and anti-inflammatory agents were disclosed. Other embodiments include methods of fabricating drug-impregnated implantable medical devices. 1. A drug-impregnated bioabsorbable stent , the stent , comprising: a stent body fabricated from a biodegradable polyester polymer and at least one therapeutic agent impregnated inside the biodegradable polymer stent body , wherein the at least a port of the therapeutic agent is crystallize. The therapeutic agent is selected from the groups consisting of immunosuppressant agent , anti-neoplastic agent , or/and anti-inflammatory agents.2. The stent of claim 1 , wherein said immunosuppressant agent is selected from the group consisting of sirolimus claim 1 , zotarolimus claim 1 , tacrolimus claim 1 , everolimus claim 1 , biolimus claim 1 , pimecrolimus claim 1 , supralimus claim 1 , temsirolimus claim 1 , TAFA 93 claim 1 , invamycin and neuroimmunophilins claim 1 , and combinations or analogs thereof.3. The stent of claim 1 , wherein said anti-neoplastic agent is selected from the group consisting of paclitaxel claim 1 , carboplatin claim 1 , vinorelbine claim 1 , doxorubicin claim 1 , gemcitabine claim 1 , actinomycin-D claim 1 , cisplatin claim 1 , camptothecin claim 1 , 5-fluorouracil claim 1 , cyclophosphamide claim 1 , 1-β-D-arabinofuranosylcytosine claim 1 , and combinations or analogs thereof.4. A stent of claim 1 , wherein aid anti- ...

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Номер записи: 82

04-04-2013 дата публикации

ELECTROSPUN PTFE COATED STENT AND METHOD OF USE

Номер: US20130085565A1

Автор: Dolmatch Bart, Eller Zeke, Hall John William, Kellar Robert S., Radford Robert J., Simmons Rachel Lynn

Принадлежит: Merit Medical System, Inc.

A stent or other prosthesis may be formed by coating a single continuous wire scaffold with a polymer coating. The polymer coating may consist of layers of electrospun polytetrafluoroethylene (PTFE). Electrospun PTFE of certain porosities may permit endothelial cell growth within the prosthesis. 1. A stent , comprising:a scaffolding structure configured to resist radial compression when disposed in a lumen of a patient, anda coating disposed on at least a portion of the scaffolding structure, the coating comprising a first layer of electrospun polytetrafluoroethylene (PTFE).2. The stent of wherein the stent further comprises a second layer of electrospun PTFE claim 1 , wherein the stent is generally tubular in shape and the first layer of electrospun PTFE is disposed such that it defines an inside surface of the stent and the second layer of electrospun PTFE is disposed such that it defines an outside surface of the stent.3. The stent of wherein the first layer of electrospun PTFE has an average pore size of between about 2 microns and about 8 microns.4. The stent of wherein the first layer of electrospun PTFE has an average pore size of between about 3 microns and about 5 microns.5. The stent of wherein the first layer of electrospun PTFE has an average pore size configured to permit the growth of endothelial cells on the inside surface of the stent.6. The stent of wherein the second layer of electrospun PTFE has an average pore size of about 1.5 microns or less.7. The stent of wherein the second layer of electrospun PTFE has an average pore size configured to resist tissue growth through the outside surface of the stent.8. The stent of claim 7 , further comprising a cuff adjacent an end of the stent claim 7 , the cuff configured to promote rapid cellular ingrowth into the cuff.9. The stent of wherein a tie layer is disposed between the first layer of electrospun PTFE and the second layer of electrospun PTFE.10. The stent of wherein the tie layer comprises PTFE.11. ...

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Номер записи: 83

11-04-2013 дата публикации

Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS

Номер: US20130087270A1

Автор: Askaryar Homayon, Glauser Thierry, Hossainy Syed Faiyaz, Lin Qing, Tang Yiwen

Принадлежит:

Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. 111-. (canceled)12. A method of forming a coating on an implantable medical device , comprising:a) forming a coating comprising nano- or micro-particles of a drug in crystalline or partially crystalline form onto at least a portion of an implantable medical device, andb) wrapping the implantable medical device on top of the coating comprising the nano- or micro-particles of the drug with a sheet of a polymer; andc) heating the sheet of the polymer at a temperature above the glass transition temperature of the polymer to form a coating comprising the polymer on top of the nano- or micro-particles of the drug.1321-. (canceled)22. The method of claim 12 , wherein the polymer is selected from the group consisting of poly(ethylene glycol terephthalate)-co-poly(butylene terephthalate) claim 12 , hyaluronic acid claim 12 , poly(ethylene glycol) claim 12 , phosphoryl choline claim 12 , poly(amide ester) (PEA) claim 12 , poly(d claim 12 ,l-lactide) (DLPLA) claim 12 , polyhydroxyalkanoate (PHA) claim 12 , polycaprolactone (PCL) claim 12 , poly(vinylidene fluoride) (PVDF) claim 12 , poly(hexafluoro propylene) (HFP) claim 12 , poly(ethylene vinyl alcohol) claim 12 , and combinations thereof.2327-. (canceled)28. The method of claim 22 , wherein the drug is selected from the group consisting of ABT-578™ claim 22 , paclitaxel claim 22 , docetaxel claim 22 , paclitaxel derivatives claim 22 , tacrolimus claim 22 , pimecrolimus claim 22 , batimastat claim 22 , mycophenolic acid claim 22 , estradiol claim 22 , clobetasol claim 22 , dexamethasone claim 22 , rapamycin claim 22 , 40-O-(2-hydroxy)ethyl-rapamycin (everolimus) claim 22 , 40-O-(3-hydroxy)propyl-rapamycin claim 22 , 40-O-(2-hydroxy)ethoxy]ethyl-rapamycin claim 22 , 40- ...

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Номер записи: 84

11-04-2013 дата публикации

Radially expandable polymer prosthesis and method of making same

Номер: US20130090718A1

Автор: Brenna Hearn Lord, Nicole F. Hou, Timothy A. Limon

Принадлежит: Abbott Cardiovascular Systems Inc

Polymeric stents having fracture toughness and resistance to recoil after deployment are disclosed along with methods of manufacturing such stents. Improvements to mechanical characteristics and other improvements may be achieved by having polymer chains within individual stent struts oriented in a direction that is closer to or in line with the axis of the individual stent struts. The struts are connected to each other by hinge elements that are configured to bend during crimping and deployment of the stent. Ring struts form ring structures. A ring structure can have an overall curvilinear length from about 12 mm to about 15 mm.

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Номер записи: 85

11-04-2013 дата публикации

Highly Flexible Stent and Method of Manufacture

Номер: US20130090719A1

Автор: Bales, Jahrmarkt Scott L., Jr. Thomas O., Kratsch Peter K., Slater Charles R.

Принадлежит: C. R. BARD, INC.

Preferred embodiments of a stent with a high degree of flexibility are shown and described. The stent can include a continuous helical winding having interconnected struts joined at vertices, and having bridges connecting sections of the helical winding to each other. An annular ring can be provided at one or both ends of the helical winding, and the annular ring can have five extensions extending to connect to the helical winding. One of the extensions can connect to a bridge and another extension can connect to a vertex. The struts at the ends of the helical winding can have strut lengths that differ from the strut lengths of the struts in a central portion of the winding between the ends of the winding. 1. A method of manufacturing an implantable prosthesis , comprising:forming a first pattern defining a continuous helical winding having a plurality of circumferential sections circumscribing a longitudinal axis from a first end to a second end, the circumferential sections being spaced apart along the axis and including a plurality of struts joined together end-to-end, the end-to-end joining of two struts of the plurality of struts defining a vertex between the two struts, a plurality of bridges connecting one circumferential section to an adjacent circumferential section; andforming a second pattern defining an annular ring having five extensions with a first extension and a second extension extending from the annular ring connecting to the first or second ends of the continuous helical winding, the first extension connecting to an end vertex at the first or second end, the second extension connecting to one of the plurality of bridges, the annular ring including a plurality of struts with adjacent struts joined together.2. The method according to claim 1 , wherein the forming a first pattern comprises forming the plurality of bridges to have a minimum width greater than a width of any of the plurality of struts.3. The method according to claim 1 , wherein the ...

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Номер записи: 86

11-04-2013 дата публикации

DEVICE FOR SPLINTING A CAVITY, ORGAN DUCT AND/OR VESSEL

Номер: US20130090720A1

Автор: MAHR RICHARD, PFEFFER JOACHIN GEORG

Принадлежит:

The invention relates to a device for splinting and/or maintaining a cavity, an organ duct and or a vessel in a human or animal body, said device including at least one compressible and self-expanding stent that is composed of at least three phases. 1. A device for the splinting and/or holding open of a cavity , organ duct and/or vessel in the human or animal body , the device comprising at least one stent which is compressible in a tube and is self-expanding , wherein the stent comprises at least three phases , wherein at least two of these phases are functional phases and at least one of these phases is a transition phase.2. The device according to claim 1 , wherein the two or more functional phases have different degrees of expansion and wherein the cavity claim 1 , organ duct and/or vessel is splinted and/or held open by those functional phases of the stent with the greater degree of expansion.3. The device according to claim 2 , wherein the functional phases of the stent comprise a distal phase and a proximal phase and the distal phase of the stent has a greater degree of expansion than the proximal phase.4. The device according to claim 3 , wherein the distal phase of the stent has a length of 0.5 cm to 20 cm claim 3 , the tube a length of 0.5 cm to 50 cm and the whole stent a length of 2 cm to 50 cm.5. The device according to claim 3 , wherein the distal phase-has a smaller degree of expansion than the proximal phase of the stent.6. The device according to claim 3 , wherein the stent has a net structure and/or a multiplicity of openings claim 3 , wherein the openings of the transition phase are larger than those of the functional phases.7. The device according to claim 3 , wherein the functional phases and the transition phases are made of at least one continuous wire claim 3 , fibre claim 3 , thread claim 3 , woven fabric or interlaid scrim.8. The device according to claim 7 , wherein the transition phase in each case at least two sections of the wire are ...

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Номер записи: 87

11-04-2013 дата публикации

Highly Flexible Stent and Method of Manufacture

Номер: US20130090721A1

Автор: Bales, Jahrmarkt Scott L., Jr. Thomas O., Kratsch Peter K., Slater Charles R.

Принадлежит: C. R. BARD, INC.

Preferred embodiments of a stent with a high degree of flexibility are shown and described. The stent can include a continuous helical winding having interconnected struts joined at vertices, and having bridges connecting sections of the helical winding to each other. An annular ring can be provided at one or both ends of the helical winding, and the annular ring can have extensions extending to connect to the helical winding. One of the extensions can connect to a bridge and another extension can connect to a vertex. The struts at the ends of the helical winding can have strut lengths that differ from the strut lengths of the struts in a central portion of the winding between the ends of the winding. 1. A method of manufacturing an implantable prosthesis , comprising:forming a first pattern defining a continuous helical winding having a plurality of circumferential sections circumscribing a longitudinal axis from a first end to a second end, the circumferential sections being spaced apart along the axis and including a plurality of struts joined together end-to-end, the end-to-end joining of two struts of the plurality of struts defining a vertex between the two struts, a plurality of bridges connecting one circumferential section to an adjacent circumferential section; andforming a second pattern defining an annular ring having a first extension and a second extension extending therefrom and connecting to the first or second ends of the continuous helical winding, the first extension connecting to an end vertex at the first or second end, the second extension connecting to one of the plurality of bridges, the annular ring including a plurality of struts with adjacent struts joined together.2. The method according to claim 1 , wherein the forming a first pattern comprises forming the plurality of bridges to have a minimum width greater than a width of any of the plurality of struts.3. The method according to claim 1 , wherein the forming a first pattern comprises ...

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Номер записи: 88

11-04-2013 дата публикации

MULTI-COMPONENT BIFURCATED STENT-GRAFT SYSTEMS

Номер: US20130090722A1

Автор: Benary Rafi, Shalev Alon

Принадлежит: ENDOSPAN LTD.

A multiple-component expandable endoluminal system for treating a lesion at a bifurcation including a self expandable tubular root member having a side-looking engagement aperture, a self expandable tubular trunk member comprising a substantially blood impervious polymeric liner secured therealong; both having a radially compressed state adapted for percutaneous intraluminal delivery and a radially expanded state adapted for endoluminal support. 1. A stent graft system comprising:a first component, which comprises a tubular structure, which comprises a first support element and a first covering element attached to said first support element, two sides of said first component being positionable, respectively, in first and second branches that branch from a main trunk of a subject, wherein said first covering element is shaped so as to define an opening arranged to face said main trunk; anda second component, which comprises a second support element and a second covering element attached to said second support element,wherein said second component comprises a proximal segment and a distal segment, said proximal segment being dimensioned to be anchorably disposed within said first component, such that said distal segment of said second component extends out of said first component through said opening,wherein a diameter of a distal section of said distal segment not disposed within said first component is greater than a diameter of said opening, andwherein said diameter of said distal section increases as said distal section exits from said opening.2. The stent graft system according to claim 1 , wherein said first component is adapted for transluminal delivery for transport to a site within a body lumen by being radially compressed from a larger cross-section to a smaller cross-section.3. The stent graft system according to claim 1 , wherein said second component is adapted for transluminal delivery for transport to a site within a body lumen by being radially ...

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Номер записи: 89

18-04-2013 дата публикации

Adjustable Support For Tubular Medical Device Processing

Номер: US20130091680A1

Автор: Adam K. Hoopai

Принадлежит: Abbott Cardiovascular Systems Inc

An apparatus and method for supporting a tubular medical device, such as a stent or scaffold, includes a rod disposed between two collets. The rod can be shaped to form a range of different size or length helical supports to support a wide range of tubular medical devices. The rod is shaped into a full or partial helix by rotating one of the collets relative to the other.

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Номер записи: 90

18-04-2013 дата публикации

Composite ePTFE/Textile Prosthesis

Номер: US20130095264A1

Автор: Chouinard Paul F., Dong Jerry, Haverkost Patrick A., Kujawski Dennis, Rakos Ronald, Sowinski Krzysztof

Принадлежит: MAQUET CARDIOVASCULAR LLC

A composite intraluminal prosthesis which is preferably used as a vascular prothesis includes a layer of ePTFE and a layer of textile material which are secured together by an elastomeric bonding agent. The ePTFE layer includes a porous microstructure defined by nodes interconnected by fibrils. The adhesive bonding agent is preferably applied in solution so that the bonding agent enters the pores of the microstructure of the ePTFE. This helps secure the textile layer to the ePTFE layer. 1. A composite multilayer implantable structure comprising:a first layer from a textile material;a second layer formed of expanded polytetrafluoroethyene; andan elastomeric bonding agent formed from an aromatic polycarbonate urethane applied to one of said first and second layers.23-. (canceled)4. A composite structure of wherein said first layer comprises a textile pattern selected from the group comprising knits claim 1 , weaves claim 1 , stretch-knits claim 1 , braids claim 1 , non-woven textile structures and combinations thereof.52. A composite structure of claim wherein said first layer is placed in contact with said one surface of said second layer.6. A composite structure of wherein said first and second layers are substantially planar.7. A composite structure of wherein said first and second planar layers form a vascular patch.8. A composite structure of wherein said vascular patch includes said first layer being a blood contact layer and said second layer being a tissue contacting layer.9. A composite structure of wherein said first and second layers are substantially tubular and wherein said first layer comprises a knitted textile pattern.10. A composite structure of wherein said first and second layers are substantially tubular and form an elongate tubular vascular graft.11. (canceled)12. A composite structure of wherein said first layer of the vascular graft is adapted for contacting blood is positioned interior to said second layer adapted for contacting tissue.13. A ...

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Номер записи: 91

18-04-2013 дата публикации

DEVICE AND METHODS FOR MEASURING AND TREATING AN ANATOMICAL STRUCTURE

Номер: US20130096409A1

Автор: Hiltner Jason Fredrick, Taylor William J.

Принадлежит: ACIST MEDICAL SYSTEMS, INC.

A sensor delivery device and methods of using the device are provided, wherein the sensor delivery device includes a sensor that is adapted to obtain a measurement that can be used to calculate cross-sectional area of a surrounding anatomical structure. In certain cases, the sensor is an electrode arrangement, wherein the electrode arrangement generates a current and measures voltage resulting from the current. The voltage measurement is then used to calculate conductivity of fluid in the surrounding anatomical structure and thus cross-sectional area. 1. An intravascular sensor delivery device comprising:a distal sleeve having a guidewire lumen for slidably receiving a medical guidewire;a first sensor coupled to the distal sleeve, wherein the first sensor is adapted to measure blood pressure and generate a signal representative of the blood pressure;a second sensor coupled to the distal sleeve, wherein the second sensor is adapted to measure cross-sectional area of a surrounding anatomical structure and generate a signal representative of the cross-sectional area;a proximal portion coupled to the distal sleeve, the proximal portion comprising a communication channel, wherein the communication channel communicates the signal from the first sensor and the signal from the second sensor to a location outside of the patient.2. The device of wherein the second sensor comprises an electrode arrangement.3. The device of wherein the electrode arrangement includes source electrodes and sense electrodes claim 2 , wherein the source electrodes generate a current and the sense electrodes measure voltage resulting from the current.4. The device of wherein the signal representative of the cross-sectional area is the voltage measured by the sense electrodes.5. The device of wherein the electrode arrangement includes two source electrodes and two sense electrodes.6. The device of wherein the source electrodes and the sense electrodes are ring-shaped electrodes that surround a ...

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Номер записи: 92

18-04-2013 дата публикации

Method and apparatus for treating a patient by intentionally occluding a blood vessel, including method and apparatus for inducing weight loss in a patient by intentionally occluding the celiac artery

Номер: US20130096580A1

Автор: Reynolds M. Delgado, William E. Cohn

Принадлежит: Reynolds M. Delgado, William E. Cohn

A method for inducing weight loss in a patient, the method comprising: intentionally occluding a blood vessel so as to create hypoperfusion in a gastrointestinal organ serviced by the blood vessel, whereby to interfere with normal gastrointestinal function and thereby induce weight loss in a patient.

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Номер записи: 93

18-04-2013 дата публикации

Medical Implant Maintaining Gaps upon Crimping, Method and Delivery Device

Номер: US20130096664A1

Автор: Hou-Sen Lim, Wolfgang Goetz

Принадлежит: Transcatheter Technologies GmbH

An implant, intended to be detachably fixed or crimped on a portion or an outer surface of a catheter for being delivered to an implantation site, includes a longitudinal axis, or an inner space or inner volume longitudinally extending within the implant, and a radial direction perpendicular to the longitudinal axis, space or volume. The implant includes a first structural element having a first portion, a second structural element having a second portion, and one or more interconnecting elements arranged between the first and the second structural elements. In the implant, the first portion and/or the second portion is/are located less radially as regards the longitudinal axis, inner space, or volume than a third portion of the one or more interconnecting elements.

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Номер записи: 94

18-04-2013 дата публикации

OPTIMAL RATIO OF POLAR AND BENDING MOMENT OF INERTIA FOR STENT STRUT DESIGN

Номер: US20130096668A1

Автор: ABUNASSAR CHAD

Принадлежит: Abbott Cardiovascular Systems Inc.

An intravascular stent is provided to be implanted in coronary arteries and other body lumens. The transverse cross-section of at least some of the stent struts have a ratio of polar and bending moments of inertia, which results in optimal resistance to stent twisting. This resistance to twisting ratio for the stent struts minimizes out of plane twisting of the struts or projecting edges of the struts when the stent is expanded from a compressed diameter to an expanded diameter in a coronary artery. 117-. (canceled)18. A stent , comprising:an elongated tubular member having struts forming a stent pattern comprising cylindrical rings connected by links;the struts having a transverse cross-section that is a four sided polygon, a first side and a second side are opposite each other and have the same length;a third side and a fourth side are opposite each other and spaced apart by a distance h;the first side and second side are not parallel to each other and the third side and the fourth side are parallel to each other; andthe lengths of the first side, second side, third side and fourth side are selected so that a ratio of twisting resistance to bending resistance in the struts is 1.51.19. The stent of claim 18 , wherein the third side is shorter than the fourth side and forms an inner surface of the elongated tubular member.20. The stent of claim 19 , wherein the fourth side forms an outer surface of the elongated tubular member.21. The stent of claim 18 , wherein the third side is shorter than the first side and the second side.22. The stent of claim 18 , wherein the fourth side is longer than the first side and the second side.23. The stent of claim 18 , wherein certain lengths of the fourth side range from 0.0045 inch to 0.0054 inch and certain lengths of the third side range from 0.0032 inch to 0.0045 inch claim 18 , to provide the ratio of twisting resistance to bending resistance of 1.51.24. The stent of claim 23 , wherein certain lengths of the first side and ...

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Номер записи: 95

18-04-2013 дата публикации

Expandable Medical Implant

Номер: US20130096670A1

Автор: Goetz Wolfgang, Lim Hou-Sen

Принадлежит: Transcatheter Technologies GmbH

An implant includes at least one supporting arrangement which is suited for supporting the implant at or on an implantation position, wherein both the supporting arrangement and the implant are expandable from a first diameter to a second diameter and/or are collapsible from the second diameter to the first diameter. The supporting arrangement includes bars which are connected to each other by means of connecting sections and at least one post for connecting the supporting arrangement with at least one other structure of the implant. At least two of the connecting sections differ in at least one material characteristic, for example, thickness. 1. An implant comprising:at least one supporting arrangement which is suited for supporting the implant at or on an implantation site, wherein both the supporting arrangement and the implant are expandable from a first diameter to a second diameter and/or are collapsible from the second diameter to the first diameter, wherein the supporting arrangement comprises:bars which are connected to each other, by means of connecting sections; andat least one post for connecting the supporting arrangement with at least one other structure of the implant, wherein at least two of the connecting sections differ in at least one material or one geometrical characteristic.2. An implant according to claim 1 , wherein the material or the geometrical characteristic is a thickness of at least one section of the connecting sections.311. An implant according to claim 1 , wherein a first connecting section having the smallest distance to a post has a first thickness d claim 1 , wherein thickness d is the smallest thickness of all thicknesses of the connecting sections.4221. An implant according to claim 3 , wherein a second connecting section having the next smaller distance to the post has a second thickness d claim 3 , wherein thickness d is larger than thickness d.5332. An implant according to claim 3 , wherein a third connecting section having ...

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Номер записи: 96

18-04-2013 дата публикации

NON-CIRCULAR ESOPHAGEAL STENTS AND DELIVERY SYSTEMS

Номер: US20130096692A1

Автор: Baron, SR. Todd H., Topazian Mark D., Wong Kee Song Louis-Michel

Принадлежит: Mayo Foundation for Medical Education and Research

Stents that have non-circular cross-sectional profiles and systems for delivering the stents are described herein. 1. An esophageal stent comprising:a body member comprising a first end, a second end, and a length along a longitudinal axis extending between the first end and the second end;wherein the body member has a delivery configuration and a deployed configuration, wherein the body member is expandable from the delivery configuration to the deployed configuration;and wherein, in the deployed configuration, the stent comprises a non-circular cross-sectional profile in the absence of any external constraints acting on the stent, wherein the cross-sectional profile is determined in a plane transverse to the longitudinal axis, and wherein the cross-sectional profile defines a major axis extending across a maximum dimension of the cross-sectional profile and a minor axis transverse to the major axis at a midpoint of the major axis, wherein the body member is larger across the major axis than across the minor axis.2. A stent according to claim 1 , wherein the non-circular cross-sectional profile is substantially uniform along substantially the entire length of the body member.3. A stent according to claim 1 , wherein the non-circular cross-sectional profile comprises an oval or elliptical cross-sectional profile.4. A stent according to claim 1 , wherein the body member comprises a first major axis in a first cross-sectional profile obtained at a first location proximate the first end of the body member and a central major axis in a central cross-sectional profile obtained at a central location proximate a midpoint of the length of the body member claim 1 , wherein the body member is larger across the first major axis than across the central major axis.5. A stent according to claim 4 , wherein the body member comprises a first minor axis in the first cross-sectional profile and a central minor axis in the central cross-sectional profile claim 4 , wherein the body ...

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Номер записи: 97

18-04-2013 дата публикации

VACUUM PUMP SYSTEMS FOR PROSTHETIC LIMBS AND METHODS OF USING THE SAME

Номер: US20130096694A1

Автор: Caldwell Ryan J., Chen Wei, Hansen Andrew H., Kuhar Bennett E., Nelson Andrew J., NICKEL Eric, Radcliffe Regan A., Wood Sean M., Yngve Kevin A.

Принадлежит: Northwestern University

Pump systems for use in suspension of a prosthetic device from a residual limb and methods of suspending a prosthetic device from a residual limb are disclosed. The pump systems include a mechanically activated pump having a first compression member coupled to a second compression member, a compressible bladder disposed between the first and second compression members, and coupling elements that engage and couple together the first and second compression members. The mechanically activated pump may be connected with an electrically activated pump within a fluid circuit of a hybrid pump system to provide vacuum engagement between a prosthetic device and a residual limb. 1. A pump system for use in suspension of a prosthetic device from a residual limb comprising:a mechanically activated pump having a first compression member coupled to a second compression member;a compressible bladder disposed between the first and second compression members; andcoupling elements that engage and couple together the first and second compression members, wherein all of the coupling elements are disposed about an outer perimeter of the compressible bladder.2. The pump system in accordance with claim 1 , wherein the bladder is coupled within a fluid circuit that is configured to provide vacuum engagement with the residual limb.3. The pump system in accordance with claim 2 , wherein the pump system is incorporated into a prosthetic device that further comprises a socket that is configured to receive the residual limb and the fluid circuit is connected to the socket.4. The pump system in accordance with claim 3 , wherein the prosthetic device further comprises a knee joint claim 3 , and the socket is configured to receive a transfemoral residual limb with the mechanically activated pump being positioned above the knee joint of the prosthetic device.5. The pump system in accordance with claim 3 , wherein the socket is configured to receive a transtibial residual limb.6. The pump system in ...

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Номер записи: 98

25-04-2013 дата публикации

Methods for Making a Supported Graft

Номер: US20130102839A1

Автор: Banas Christopher E., Edwin Tarun J., Kowligi Rajagopal R., McCrea Brendan

Принадлежит: BARD PERIPHERAL VASCULAR, INC.

A method for preparing a stent-graft for intraluminal delivery, including positioning an expanded polytetrafluoroethylene (ePTFE) substrate over a support mandrel, coupling a shape memory member to a polymer cladding to form a polymer clad member, winding the polymer clad member in an overlapping helical manner onto a surface of the ePTFE substrate, joining and sealing adjacent overlapping regions of the polymer clad member together and to the surface of the ePTFE substrate to form a stent-graft, manipulating the stent-graft from a larger first diameter to a smaller second diameter, and loading the stent-graft into a restraining sheath at the smaller second diameter. 1positioning an expanded polytetrafluoroethylene (ePTFE) substrate over a support mandrel;coupling a shape memory member to a polymer cladding to form a polymer clad member;winding the polymer clad member in an overlapping helical manner onto a surface of the ePTFE substrate;joining and sealing adjacent overlapping regions of the polymer clad member together and to the surface of the ePTFE substrate to form a stent-graft;manipulating the stent-graft from a larger first diameter to a smaller second diameter; andloading the stent-graft into a restraining sheath at the smaller second diameter.. A method for preparing a stent-graft for intraluminal delivery, comprising: This application is a continuation of U.S. patent application Ser. No. 13/434,472, filed Mar. 29, 2012, which is a continuation of U.S. patent application Ser. No. 12/546,483, filed Aug. 24, 2009, now U.S. Pat. No. 7,578,899, which is a continuation of U.S. patent application Ser. No. 11/429,849, filed May 8, 2006, now U.S. Pat. No. 7,578,899, which is a continuation of U.S. patent application Ser. No. 10/431,685, filed May 8, 2003, now U.S. Pat. No. 7,060,150, which is a divisional of U.S. patent application Ser. No. 09/855,918, filed May 15, 2001, now abandoned, which is a divisional of U.S. patent application Ser. No. 08/999,583, filed ...

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Номер записи: 99

25-04-2013 дата публикации

METHOD AND APPARATUS FOR ENDOVASCULAR THERAPY OF AORTIC PATHOLOGY

Номер: US20130103132A1

Автор: Madjarov Jeko Metodiev

Принадлежит: THE CHARLOTTE-MECKLENBURG HOSPITAL AUTHORITY d/b/a CAROLINAS HEALTHCARE SYSTEM

Assemblies, devices, and methods for positioning the same proximate a target site within a body lumen are provided. The assembly includes first and second components that can function independently of one another to address a patient's vascular abnormalities or can cooperate to form an assembly. The assembly is designed to address aortic pathologies near clusters of arterial branches in a way that allows blood to continue flowing to the arterial branches during the procedure while providing an adequate landing zone for the adjoining component. One of the components may include a tapered portion near one end that can be received by a corresponding end of the other component. Alternatively, one of the components may include an invaginated end that is able to receive a corresponding end of the other component such that the position of each component is substantially fixed with respect to the other. 1. A vascular assembly for treating a target site within a body lumen comprising:a first component defining a first end, a second end, and a lumen extending therebetween; anda second component defining a first end, a second end, and a lumen extending therebetween, wherein the second end of the second component is configured to receive the second end of the first component,wherein the first component is configured to engage an inner surface of a vessel wall proximate a first group of arterial branches at the target site,wherein the second component is configured to engage an inner surface of the vessel wall proximate a second group of arterial branches at the target site, andwherein each of the first and second components is independently deployable to the target site and is configured for use at the target site both independently of the other component and in cooperation with the other component.2. The vascular assembly of claim 1 , wherein the second end of at least one of the first and second components has a smaller inner diameter than the first end of the respective ...

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Номер записи: 100

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