Tobacco NEIP1 protein, coding gene and applications

The invention discloses a tobacco NEIP1 protein, coding gene and applications. The protein is the following (a) or (b), (a) is a protein composed of amino acid sequences shown in sequence 2 in a sequence table, and (b) is a protein derived from the sequence 2 through replacement and/or lack and/ or addition of one or of several amino acid residues of the amino acid sequences shown in the sequence 2 in a sequence table, and relevant to plant biomass or the lotus throne size. Proved by experiments, the protein can regulate and control the phenotype of plants such as leaf blades and lotus thrones, and is important for cultivation of plant species with addition of leaf blades and lotus thrones and especially edible vegetable plant species of cruciferae and the like.

Application of 7S,8R,8'R-(+)-lariciresinol-4,4'-bi-O-beta-D-glucopyranoside in preparing medicines

The invention discloses a preparation method of 7S,8R,8'R-(+)-lariciresinol-4,4'-bi-O-beta-D-glucopyranoside and an application of 7S,8R,8'R-(+)-lariciresinol-4,4'-bi-O-beta-D-glucopyranoside in preparing Anti-influenza virus medicines. The 7S,8R,8'R-(+)-lariciresinol-4,4'-bi-O-beta-D-glucopyranoside has direct therapeutic effects in Influenza A virus infection, can be orally taken, and is easy to take. The 7S,8R,8'R-(+)-lariciresinol-4,4'-bi-O-beta-D-glucopyranoside is a pure natural product, thus compared with western medicines, the 7S,8R,8'R-(+)-lariciresinol-4,4'-bi-O-beta-D-glucopyranoside is less likely to generate drug resistance.

Rice stress tolerance-related receptor type protein OsSIK2, as well as encoding gene and application thereof

The invention discloses a rice stress tolerance-related receptor type protein OsSIK2, as well as an encoding gene and application thereof. The protein provided by the invention is of (a) or (b) as follows: (a) the protein constituted by the amino acid sequence as shown in the sequence 2 in a sequence table; and (b) the protein which is related to plant stress tolerance and derived from (a) by performing substitution and/or deletion and/or addition on one or a plurality of amino acid residues in the amino acid sequence as shown in the sequence 2 in the sequence table. The protein disclosed by the invention has an important value for culturing stress-tolerant plant varieties, particularly culturing crops with tolerance to abiotic stress (salt tolerance), forest grass and other new species, can be used for culturing and identifying the stress-tolerant plant varieties required for farming and animal husbandry as well as control of an ecologic environment, and has important significance for ...

Post-treatment detection method and system based on net-harddisk video recorder dangerous invasion

The invention discloses a post-treatment detection method and a system based on net-harddisk video recorder dangerous intrusion. The post-treatment detection method comprises the following steps: reading a surveillance video file of a net-harddisk video recorder, and scanning a start frame to an end frame of an image frame sequence; obtaining all the image frames, obtaining a background model figure through traverse contrast; extracting a mobile object figure in the surveillance video on the basis that the background model figure is used as a reference figure; extracting motion features of the mobile object figure, building a rectangular coordinate system based on a scene, and carrying out three kinds of algorithm model detections on the mobile object figure in random order; outputting a detection result of the three kinds of algorithm models, wherein the detection result comprises an intrusion type, an intrusion start time and an intrusion end time. Due to the fact that the post-treatment ...

Method for preparing alpha-crystal-form imatinib mesylate

The invention discloses a method for preparing high-purity alpha-crystal-form imatinib mesylate, which belongs to the technical field of discovery and preparation of medicinal crystal forms. The method includes four steps of the step (A), the step (B), the step (C) and the step (D), wherein the step (A) includes dissolving imatinib by absolute ethyl alcohol on the condition of backflow and obtaining settled solution; the step (B) includes diluting methanesulfonic solution by dropping ethyl acetate; the step (C) includes decreasing temperature gradually, adding a few of crystal forms, cooling to the room temperature; and the step (D) includes washing solid obtained by ethyl acetate and drying in vacuum. The alpha-crystal-form imatinib mesylate prepared is determined to be high-purity alpha-crystal-form methanesulfonic acid imatinib after being subjected to X-ray powder diffraction, infrared spectrum and thermoanalysis, seed crystal in proper quantity is added during crystallization, crystallization ...

Reclaimed waste carpet fiber reinforced cement-based composite material, and preparation method and application thereof

The invention relates to a reclaimed waste carpet fiber reinforced cement-based composite material, and a preparation method and an application thereof. The invention provides the reclaimed waste carpet fiber reinforced cement-based composite material, which is energy-saving and environment-friendly and has a simple process. The reclaimed waste carpet fiber reinforced cement-based composite material consists of the following components in percentage by weight: 15.2 to 50.5 percent of cement, 12.1 to 35.8 percent of mineral admixture, 10.2 to 31.5 percent of stone, 18.2 to 24.2 percent of sand, 6.5 to 18.5 percent of water, 1.4 to 2.8 percent of carpet fiber, 1.0 to 2.8 percent of water-reducing agent and 0.1 to 0.2 percent of thickening agent. The preparation method comprises the following steps: stirring the cement, the mineral admixture, the stone, the sand and the carpet fiber uniformly; adding the water, the water-reducing agent and the thickening agent; and stirring to form pasty slurry ...

Soybean transcription active protein GmPHD6, and coding gene and application thereof

The invention discloses a soybean transcription active protein GmPHD6, and a coding gene and application thereof. The soybean PHD transcription factor is: (a) a protein composed of an amino acid sequence shown as Sequence 2 in a sequence table; or (b) a protein which is derived from the Sequence 2, is formed by the amino acid sequence shown as the Sequence 2 in the sequence table through the substitution and/or deletion and/or addition of one or some amino acid residues and is related to stress tolerance of plants. Experiments of the invention prove that the soybean PHD transcription factor GmPHD6 and the coding gene thereof can be used for the cultivation of stress-tolerant plant species, especially stress-tolerant soybean species such as salt-tolerant and drought-tolerant soybeans.

Plant adverse resistance related transcription factor GmWRKY78 as well as encoding gene and application thereof

The invention discloses a plant adverse resistance related transcription factor GmWRKY78 as well as an encoding gene and application thereof. The protein provided by the invention is shown as (a) or (b): (a) represents a protein consisting of amino acid sequences shown in a sequence 1 in a sequence table; and (b) represents a protein which is obtained by carrying out substitution and/or deletion and/or addition of one or more amino acid residues on the amino acid sequence shown in the sequence 1 in the sequence table, is related to plant adverse resistance and is derived from the sequence 1. The plant adverse resistance related transcription factor GmWRKY78 has important value in the aspects of culturing adverse-resistance plant varieties, particularly new varieties such as abiotic stress resistance (salt resistance, drought resistance and low-temperature resistance) crops and grasslands, can be used for culturing and identifying adverse resistance plant varieties required by agriculture ...

Uses of unsaturated fatty acids for inhibiting virus replication and /or infection

Uses of unsaturated fatty acid linoleic acid and docosenoic acid or pharmaceutically acceptable salts or esters thereof for inhibiting hepatitis C virus replication or preventing and/or treating hepatitis C virus inflection are disclosed.

Oxyntomodulin analogs and methods of making and using same

Provided are oxyntomodulin analogs. The peptide analogs have at least two cysteines. The two cysteines are separated by six amino acids such that they can be crosslinked using suitable crosslinking moieties. The crosslinked peptides have long half-lives and/or efficacy. For example, peptide analog compositions are used for inducing weight loss and/or reducing blood glucose levels.

Cotton Trihelix transcription factor GhGT23, coding genes and applications

The invention discloses a cotton Trihelix transcription factor GhGT23, coding genes and applications. The protein provided by the invention is a cotton Trihelix transcription factor protein, named after GhGT23 and coming from cotton (Gossypium), and is the following (a) or (b): (a) is a protein composed of amino acid sequences shown in sequence 2 in a sequence table, and (b) is a protein derived from the sequence 2 through replacement and/or lack and/ or addition of one or of several amino acid residues of the amino acid sequences shown in the sequence 2 in a sequence table, and relevant to stress tolerance of plants. The protein is important for cultivation of plant species with stress tolerance and especially new species with abiotic stress tolerance (salt tolerance), such as crops, forest grasses and the like, can be used for cultivation and identification of plant species, with stress tolerance, needed by agriculture and animal husbandry and ecological environmental management, and ...

Method for detecting picrasma quassioides alkali content in picrasma quassioides

The invention relates to the analytical chemistry field, particularly to a method for detecting picrasma quassioides alkali content in picrasma quassioides. The method comprises the following steps: preparing 1-carbomethoxy-Beta-carboline, nigakinone, and metiiylnigakinone standard solutions and drawing a standard curve; drying and smashing picrasma quassioides, and extracting to obtain a solution to be detected; detecting, wherein the detection chromatographic condition is that a C18 chromatographic column is adopted, the column temperature is 20-40 DEG C, the detection wave length is 205-280 nm, acetonitrile is taken as an A phase of a mobile phase while acid water is taken as a B phase of the mobile phase, the flow velocity is 1 mL/minute, and the elution procedures are performed in the way that the volume percent of acetonitrile is changed from 5% to 45% during the period from 0 minutes to 35 minutes, from 45% to 80 % during the period from 35 minutes to 40 minutes, from 80% to 90% ...

Network audio/video monitoring framework and communication method thereof

The invention is applicable in the technical field of security and provides a communication method for a network audio/video monitoring system. The method comprises the following steps that: A, a user side accesses into a cloud service side and transmits audio/video data subscription demand information to the cloud service side and the cloud service side transmits information for confirming subscription success to the user side after receiving the subscription demand information, wherein the user side is a registered user of the cloud service end; B, the cloud service side controls the corresponding audio/video equipment side to transmit the subscribed audio/video data to the user side according to the subscription demand of the user side and the audio/video equipment side transmits information for confirming that the subscription demand is received, wherein the audio/video equipment side is an audio/video data providing side authenticated by the cloud service side; and C, the audio/video ...

Anti-glyphosate EPSP (enolpyruvyl shikimate phosphate) synthase GmEPSPS-2 as well as encoding gene and application thereof

The invention discloses an anti-glyphosate protein as well as an encoding gene and application of the anti-glyphosate protein. The protein, provided by the invention, is the following (a), (b) or (c): (a) the protein consists of amino acid sequences shown at 56th-532th position of the sequence 1 in a sequence table; (b) the protein consists of amino acid sequences shown by the sequence 1 in a sequence table; and (c) the protein with glyphosate resistance is derived from the sequence 1 and subjects the amino acid sequences of (a) or (b) to substitution and/or deletion and/or addition of one or more amino acid residues. The GmEPSPS-2 protein and the encoding gene of the GmEPSPS-2 protein, provided by the invention, have remarkable resistance effect on glyphosate phytocide; experiments prove that GmEPSPS-2 transgenic tobaccos and GmEPSPS-2 transgenic corns can grow normally under the action of 0.15% glyphosate, while growth of the non-transgenic tobaccos or corns are obviously inhibited, leaves ...

Inspection method capable of inspecting traditional Chinese medicine injection tannins

The invention relates to an inspection method capable of inspecting traditional Chinese medicine injection tannins, and is used for inspecting the tannin impurities of a traditional Chinese medicine injection to control the quality of the traditional Chinese medicine injection. The inspection method provided by the invention is characterized by comprising the following steps: 1) coating a protein absorption membrane with proteins; 2) enabling a traditional Chinese medicine injection solution to be in contact with the protein coated membrane; 3) washing protein coated membrane by utilizing the solution containing organic solvents; and 4) observing the color of sample application speckles and judging the tannins in the traditional Chinese medicine injection. In the inspection method provided by the invention, the concentration of the tannins in the traditional Chinese medicine injection which are inspected by adopting a sample application mode and can reach 0.75-0.25mg/ml, can reach 0.07mg ...

Atriplex hortensis transcriptional active protein AhPHD1, its coding gene and application

The invention discloses an Atriplex hortensis transcriptional active protein AhPHD1 (Atriplex hortensis plant homodomain), its coding gene and application. The protein is named as AhPHD1, and is a protein with one of the following amino acid residue sequences: 1) the sequence 2 in a sequence table; and 2) the protein that is obtained by substituting and/or deleting and/or adding an amino acid residue sequence of the sequence 2 in the sequence table with one or several amino acid residues and is related to plant stress tolerance. Experiments of the invention prove that, the Atriplex hortensis protein and its coding gene can be used for cultivating stress tolerant plant varieties, particularly salt-tolerant dicotyledon varieties.

Preparation method of rare earth-modified oxygen-carrying carbon nanotube

The invention relates to a preparation method of a rare earth-modified oxygen-carrying carbon nanotube. The method comprises the following steps of: (1) submerging a functionally-treated carbon nanotube into a rare earth modifier at the room temperature for 2-4 hours, ultrasonically dispersing for 1-3 hours, filtering and drying; (2) putting the dried carbon nanotube into a sample room, heating the sample room to 300-400 DEG C, vacuumizing till the vacuum degree is over 10<-3>Pa, keeping the sample room in a vacuum state, and introducing high-purity oxygen of 9-10MPa after the sample room is naturally cooled to the room temperature; and (3) recording the pressure intensity change in the sample room simultaneously to obtain a product 2-3 hours after the pressure intensity stops falling. Compared with the prior art, the rare earth-modified oxygen-carrying carbon nanotube has the advantages of nontoxicity, excellent sensitivity enhancing performance, high dispersivity and the like.

New purpose of medicine for treating stomatitis

The invention discloses the application of a traditional Chinese preparation for treating stomatitis in the preparation of a micro-ecological regulator for preventing and treating intestine, stomach and mouth cavity diseases. A large amount of experiments indicate that the traditional Chinese preparation disclosed by the invention has good prevent and treatment effects on the intestine, stomach and mouth cavity flora disequilibrium caused by antibiotics.

Method and device for displaying click condition of web page

The invention discloses a method and a device for displaying a click condition of a web page. The method includes that numbers of clicks of pixels in the web page are acquired after a server receives a web page click information acquisition request transmitted by a terminal, and the numbers of clicks of the various pixels are determined respectively; and the numbers of clicks of the various pixels are transmitted to the terminal by the server, so that the terminal can determine display attributes of the various pixels in a heat display diagram of the web page according to the numbers of clicks of the various pixels and click rates respectively, and the heat display diagram of the web page can be generated according to the display attributes of the various pixels in the heat display diagram of the web page. By the method, the accuracy for displaying the click condition of the web page can be improved, and the accuracy for judging the click condition of the web page is improved.

Automatic illumination compensation method and system of video image

The invention is suitable for the technical field of multimedia data process, and provides an automatic illumination compensation method which comprises the following steps of: step A, separating a white component signal from a video signal; step B, converting the video signal into a pre-modulation color component signal and filtering stray lights; step C, respectively carrying out weighting operation on the white component signal and the color component signal according to a preset weight value to obtain a first compensation video signal; step D, carrying out the weighting operation on the first compensation video signal and the color component signal according to the preset weight value to obtain a second compensation video signal; step E, filtering and removing surrounding lights on the white component signal and the second compensation video signal; and step F, carrying out white balance regulation on the white component signal and the second compensation video signal after the surrounding ...

Method and device for acquiring font files of target characters in document files

The invention discloses a method and device for acquiring font files of target characters to be presented in document files. The method includes the steps of receiving a first request, for requesting the font files of the target characters in the document files, from user equipment, acquiring document files corresponding to document identification according to the document identification in the first request, extracting font information corresponding to the target characters from the acquired embedded font files in the document files according to location identification in the first request, generating font files of the document type which can be supported by a document display client side of the user equipment according to the extracted font information, and supplying the generated font files to the user equipment. The font files of the font document type which can be supported by the document display client side of the user equipment are generated according to the extracted font information ...

Use of polysaccharides from radix isatidis in manufacture of medicaments against influenza virus

Use of polysaccharides from Radix isatidis in the manufacture of medicaments for treating and/or preventing diseases induced by influenza virus and complication thereof, wherein the molecular weight of the polysaccharides from Radix isatidis is 3000-7000Da, and the influenza virus includes influenza virus A, influenza virus B, bird influenza virus, such as human influenza virus H1N1, H3N2, bird influenza virus H6N2, H7N3, H9N2 and INF B. The mechanism of the polysaccharides from Radix isatidis against influenza virus is due to the ability to inhibit the binding of influenza virus to the host cell. The present invention also discloses a pharmaceutical composition containing the polysaccharides from Radix isatidis and the method for preparing the polysaccharides.

Smart label printing system

The invention discloses a smart label printing system which comprises a processor module, a sensor module, a communication module, a printout control module, an RFID module, a red, yellow and green indicator light module, a key module and a power module. The sensor module transmits the consumable condition and the condition of a printer self to the processor module. The communication module and the processor module transmit data mutually. The key module transmits user command information to the processor module. The processor module receives the information, processes the information and then transmits the information to the printout control module. The processor module receives the information, processes the information and then exchanges data with the RFID module, and the RFID module is in wireless connection with a smart consumable module. The processor module receives the information, processes the information and then transmits the information to the red, yellow and green indicator ...

Three crystal forms of esomeprazole magnesium salt tetrahydrate and preparation method thereof

The invention relates to three crystal forms of esomeprazole magnesium salt tetrahydrate and a preparation method thereof, belonging to the technical field of detection and preparation of drug crystal forms. The invention relates to a crystal form B, a crystal form C and a crystal form D, wherein the PXRD (powder X-ray diffraction) spectrum of the crystal form B represented by the crystal face distance d has diffraction peaks at about 5.6A, 7.1A, 8.0A, 10.3A, 11.8A, 12.8A, 16.0A, 16.5A, 17.3A, 18.2A, 19.0A, 20.0A, 20.4A, 20.7A, 21.5A, 22.7A, 23.3A, 23.9A, 24.4A and 30.4A; the crystal form C has diffraction peaks at about 6.4A, 7.3A, 9.4A, 10.9A, 12.3A, 14.4A, 15.6A, 16.6A, 17.4A, 17.8A, 18.1A, 18.9A, 19.5A, 21.4A, 22.4A, 23.2A, 23.9A, 24.8A and 27.2A; and the crystal form D has diffraction peaks at about 5.0A, 7.1A, 12.1A, 14.1A, 18.7A, 21.3A, 22.4A, 23.2A and 28.4A. The invention lays foundation for development and application of new formulations of esomeprazole magnesium salt.

Irradiation crosslinked chitosan/gelatin/polyvinyl alcohol hydrogel dressing as well as preparation method and application thereof

The invention discloses an irradiation crosslinking chitosan/gelatin/polyvinyl alcohol hydrogel dressing as well as a preparation method and an application thereof. The preparation method comprises the steps that a chitosan, gelatin and polyvinyl alcohol solution is prepared by using ultrapure water serving as a solvent; the solution is stirred and mixed uniformly and then irradiated, and original hydrogel is obtained; the original hydrogel is put into the ultrapure water to be soaked; and the chitosan/gelatin/polyvinyl alcohol hydrogel dressing is prepared. The hydrogel dressing is extensive in raw material source, simple in preparation technology and stable in performance, and has the advantages of inflammation diminishing, wound pain relieving, scar reduction, wound healing promotion, wound seepage absorption, and excellent biocompatibility. The hydrogel dressing is easy to degrade after abandoned, and has a smaller influence on an environment. The hydrogel dressing can be applied to ...

Glyphosate resistant EPSP synthetase GmEPSPS, and coding gene and application thereof

The invention discloses a glyphosate resistant protein, and a coding gene and application thereof. The protein provided by the invention is (a) or (b) or (c) as follows: (a) a protein composed of an amino acid sequence shown as 73rd-504th site of a sequence 1 in the sequence table; (b) a protein composed of the amino acid sequence shown in the sequence 1 in the sequence table; and (c) a protein, derived from the sequence 1 and with glyphosate resistance, obtained by substitution and / or deletion and / or addition of one or several amino acid residues on the amino acid sequence of (a) or (b). The GmEPSPS protein and the coding gene thereof provided by the present invention have significant resistance effect on a glyphosate herbicide. Experiments prove that GmEPSPS transgenic tobacco and GmEPSPS transgenic maize can still grow normally under 0.15% of glyphosate, but non-transgenic tobacco and maize are obviously suppressed in growth, and have leaves yellowing and withered. It shows that ...

Crystallizing method for preparing alpha crystal form methanesulfonic acid imatinib

The invention discloses a simple preparation method for alpha crystal form methanesulfonic acid imatinib, which belongs to the technical field of drug crystal form discovery and preparation. The method includes four steps of (A) dripping methanesulfonic acid into suspension of imatinib and absolute ethyl alcohol at normal temperature and reacting to generate methanesulfonic acid imatinib; (B) performing micropore filtration for solution so as to obtain clear solution; (C) growing crystals for 1-2 hours at the same temperature; and (D) washing obtained solid by ethyl acetate and performing vacuum drying. The prepared alpha crystal form methanesulfonic acid imatinib crystals are determined as high-crystal-form-purity alpha crystal form methanesulfonic acid imatinib via X-ray powder diffraction, infrared spectrum and thermal analysis. A defined amount of seed crystals are added in a crystallization process, so that crystallization speed is increased obviously, and crystallization can be finished ...

Station terminal centralized control method and device based on intelligent telecontrol

The invention discloses a station terminal centralized control method and device based on intelligent telecontrol. The method comprises the steps of acquiring the transmission data of a measuring and controlling device, a protecting device, a fault recording device, an on-line monitoring device, a watt hour meter and a PMU of a station terminal according to a predetermined standard; converting the acquired transmission data into preset data models, storing the data models in entries of a transmission data table, and updating the entries according to acquiring time when the transmission data are acquired repeatedly; setting the transmission priorities of all the entries in the transmission data table according to different service classifications and instantaneity requirement classifications; sending the entries with high transmission priorities to a main dispatch station according to the sequence of the transmission priorities. According to the station terminal centralized control method ...

2,3,3,3-tetrafluoropropylene preparation method

The invention discloses a fluorination catalyst for preparing 2,3,3,3-tetrafluoropropylene. The catalyst has a structural formula of Cr1(Y, Z)0.005-0.5O0.1-1.0F1.0-3.0, wherein Y comprises one or more than two of Al, Zn and Mg, and Z is a rare earth element having an oxygen storage/evolution function. The invention also provides a 2,3,3,3-tetrafluoropropylene preparation method. The catalyst and the preparation method have the advantages of high raw material conversion rate and good product selectivity, and the life of the catalyst is long.

Arabidopsis ERIP2 protein as well as coding gene and application thereof

The invention discloses an arabidopsis ERIP2 protein as well as a coding gene and an application thereof. The protein provided by the invention is (a) or (b), wherein (a) is a protein composed of an amino acid sequence shown in a sequence 1 in a sequence list, (b) is a protein which is formed by substituting and/or deleting and/or adding one or more amino acid residues in an amino acid sequence shown in a sequence 2 and which is related to size of rosette or cotyledon of a plant and is derived from the sequence 2. Experimental results show that the arabidopsis ERIP2 protein can regulate and control phenotypes such as cotyledon and rosette of the plant and has significance in cultivation of plant varieties with blades and rosettes increased, especially in cultivation of edible cruciferae vegetables.

Networked distribution type multiple-mobile-robot system

The invention discloses a networked distribution type multiple-mobile-robot system which comprises an upper computer measurement and control system and a multiple-mobile-robot set. The upper computer measurement and control system comprises an upper computer monitoring unit and a communication network unit. Mobile robots make decisions according to sensor information obtained by a sensor detection unit and network information received by the mobile robots, operation conditions of the mobile robots are controlled, and the mobile robots operate in a coordinated mode according to a coordination algorithm of the multiple-mobile-robot set. Compared with the prior art, the networked distribution type multiple-mobile-robot system has the advantages of being simple in structure, strong in function, convenient to develop and the like. Multiple sensors replace a visual processing method, so that data processing complexity is lowered; a ZigBee wireless network based on CC2530 is constructed so that ...

Rice stress tolerance-related receptor-like protein OsSIK3, its coding gene and application

The invention discloses a rice stress tolerance-related receptor-like protein OsSIK3, its coding gene and application. The rice stress tolerance-related receptor-like protein OsSIK3 disclosed herein is the following protein of (a) or (b): (a) a protein having the amino acid sequence represented by SEQ ID No:2 in the sequence table; and (b) or a protein which is related to plant stress tolerance, is derived from (a), and has an amino acid sequence wherein one or more amino acid residues are substituted and/or deleted and/or added in the amino acid sequence represented by SEQ ID No:2 in the sequence table. The OsSIK3 gene disclosed herein can significantly raise the salt tolerance and drought tolerance. The protein disclosed herein has important values in cultivating stress-tolerant plant varieties, especially abiotic stress-tolerant (salt-tolerant) crops, trees, grass and other novel varieties, can be applied in cultivation and identification of stress-tolerant plant varieties required by ...

OXYNTOMODULIN ANALOGS AND METHODS OF MAKING AND USING SAME

Provided are oxyntomodulin analogs. The peptide analogs have at least two cysteines. The two cysteines are separated by six amino acids such that they can be crosslinked using suitable crosslinking moieties. The crosslinked peptides have long half-lives and/or efficacy. For example, peptide analog compositions are used for inducing weight loss and/or reducing blood glucose levels. 2. The crosslinked peptide of claim 1 , wherein i is at position number 17 or number 213. The crosslinked peptide of claim 1 , wherein the serine at position 2 is D-serine.4. The crosslinked peptide of claim 1 , wherein the peptide is conjugated with at least one polyethylene glycol group and/or at least one lipid group.5. The crosslinked peptide of claim 1 , wherein the amino acids at positions i+2 to i+6 have a sequence selected from the group consisting of:RAQDFV (SEQ ID NO:3), AAKEFI (SEQ ID NO:4), AVRLFI (SEQ ID NO:5), and a sequence having at least 80% homology with SEQ ID NO:3, SEQ ID NO:4, or SEQ ID NO:5.6. The crosslinked peptide of claim 1 , wherein the peptide has the following structure:HsQGTFTSDYSKYLDECAAKEFICWLMNTKRNRNNIA (SEQ ID NO:11).8. The crosslinked peptide of claim 7 , wherein R at each occurrence on the crosslinking moiety is an H.9. A fusion protein comprising a crosslinked peptide of claim 1 , a peptide spacer claim 1 , and a protein.10. A composition comprising one or more crosslinked peptide of and/or one or more fusion protein of and a pharmaceutically acceptable carrier.11. A method of lowering blood glucose level in an individual in need of treatment comprising administering a composition of to the individual claim 10 , wherein the administration results in a lowered blood glucose level.12. A method of inducing weight loss of an individual in need of treatment comprising administering a composition of to the individual claim 10 , wherein the administration results in a lowered blood glucose level. This application is a continuation of International Patent ...

Method and system for simultaneously displaying flight news and plans on same Gantt chart interface

The invention discloses a method and a system for simultaneously displaying flight news and plans on a same Gantt chart interface. The method includes steps of inputting all flight numbers of rescheduled flights; grouping planes of all rescheduled flights; respectively generating a news zone and a plan zone of each flight in the same Gantt chart, and adjacently arranging the news zones and the plan zones of the flights belonging to the same group according to grouping results; adding different marks on different flights in the same zone belonging to the same group, and adding same marks on the same flights in the different zones; outputting and displaying the Gantt chart interface added with the marks. The flight news and plans can be displayed on the same Gantt chart interface at the same time, so that convenience is brought for flight rescheduling departments to visually compare and quickly analyze the plans, and making and coordinate time for flight rescheduling plans is shortened.

Network video monitoring system, encryption/decryption method and device of video signal thereof

The invention is suitable for the technical field of security, and provides a network video monitoring system, and an encryption/decryption method and an encryption/decryption device of a video signal of the network video monitoring system. The encryption method comprises the steps: A1, separating an image signal from the collected video signal, encrypting the image signal; and A2, merging the encrypted image signal with other signals in the video signal except for the image signal into a digital signal and then outputting the digital signal. The encryption method disclosed by the invention is different from a common encryption technology, by adopting a manner of signal separating, partially encrypting, merging and then outputting the signal, and separation is needed before decryption, so that the security of the video data in a data transmission process can be improved, and the problems of copying, tampering, backing, malicious accessing the video data and the like occurred due to the ...

Production process of low-density light reinforced floor

A production process of a low-density light reinforced floor includes: overlaying melamine dipped balancing paper, a low-density fiberboard, melamine dipped decorative paper and melamine dipped abrasion-resisting paper on a paving table from top to bottom to form a slab, installing the slab and bonding the slab in a pressing mode. The density of an adopted base material is 0.40-0.80g/cm<3>, and the produced reinforced floor is light in weight, saves logistics cost and greatly reduces waste of forest resources.

Fuzzy formation and obstacle avoidance control method for multi-mobile-robot system

The invention discloses a fuzzy formation and obstacle avoidance control method for a multi-mobile-robot system. Firstly, a pilot robot detects whether an obstacle exist in a forward direction region of operation or not; if not, the operation is continued according to an original formation pattern; if yes, the multi-mobile-robot system enters an obstacle avoidance state, and then all following robots are informed through broadcasting; finally, the following robots switch the formation pattern according to kinds of stored formation information and the information broadcast by the pilot robot, and the positions in the formation pattern are determined; the steps are repeated. According to the fuzzy formation and obstacle avoidance control method, the multiple mobile robots perform formation under the unknown environment, and the robots can effectively avoid the obstacle for the operation. The pilot robot detects the obstacle information and broadcasts the switching information of the formation ...

Technique of producing fuel oil through normal-pressure catalytic cracking of tar

The invention relates to a technique of producing a fuel oil through normal-pressure catalytic cracking of tar. The technique comprises the process steps of pretreating, material feeding, catalyzing, cracking, fractionating and the like under the normal pressure condition; the used catalyst is a Y type zeolite molecular sieve, and a ceramic ring is used as a filler; the whole production process is totally closed clean continuous production; automatic neutralization is realized by an alkaline washing method; carbon residue is screened as good-quality carbon; the collected gas can be used as a fuel for daily life; according to the technique, gasoline 90#, and diesel oils 0# to -20# can be produced; the oil yield reaches up to the range from 70% to 85%; catalytic cracking is sufficient; the oil product is good in quality; the production cost is reduced.

Compound traditional Chinese medicine preparation with effects of benefiting qi and activating blood circulation for preventing and treating gastric cancer, and preparation method thereof

The invention relates to a compound traditional Chinese medicine preparation with effects of benefiting qi and activating blood circulation for preventing and treating a gastric cancer, and a preparation method thereof, and belongs to the technical field of a traditional Chinese medicine preparation for preventing and treating the gastric cancer. The technical scheme is that the compound traditional Chinese medicine preparation is prepared from the following traditional Chinese medicine components by weight percent: 15-25% of glaucescent fissistigma root, 15-25% of buckwheat leaves, 15-20% of bighead atractylodes rhizome, 10-15% of curcuma zedoary, 10-15% of semen coicis and 10-15% of brucea javanica. The preparation can be prepared into capsules, tablets, powder and the like according to the requirements; the full formula has the effects of benefiting qi and activating blood circulation, and eliminating stagnation to stop pain, and can effectively relieve epigastrium pain, swelling and ...

Breeding method for improving DHA (Docosahexaenioc Acid) content in oyster body

The invention provides a breeding method for improving DHA (Docosahexaenioc Acid) content in an oyster body, wherein purebred oysters from various subspecies or populations of the same species are used as parents; and next, hybrid progenies with high DHA content can be generated through homologous outbreeding between the subspecies or populations of the same species. With the adoption of the breeding method for improving the DHA content in the oyster body, the DHA content in the oyster body can be improved by more than 20% and the efficiency is high; in addition, techniques such as transgenosis and medication are not required by the breeding method for improving the DHA content in the oyster body; therefore, the operation is simple and convenient and the practicability is strong; the breeding method for improving the DHA content in the oyster body can enable nutritional ingredients in the oyster body to be improved remarkably, so that the problem that the nutritional quality of the current ...

Soybean transcription active protein GmPHD5, and coding gene and application thereof

The invention discloses a soybean transcription active protein GmPHD5, and a coding gene and application thereof. The soybean PHD transcription factor is: (a) a protein composed of an amino acid sequence shown as Sequence 2 in a sequence table; or (b) a protein which is derived from the Sequence 2, is formed by the amino acid sequence shown as the Sequence 2 in the sequence table through the substitution and/or deletion and/or addition of one or some amino acid residues and is related to stress tolerance of plants. Experiments of the invention prove that the soybean PHD transcription factor GmPHD5 and the coding gene thereof can be used for the cultivation of stress-tolerant plant species, and the GmPHD5 gene can obviously improve the salt tolerance and drought tolerance of plants.

Plant lateral branch number correlated transcription factor AtDOF 4.2, its encoding gene and application

The invention discloses a plant lateral branch number correlated transcription factor AtDOF 4.2, its encoding gene and an application. A protein provided by the invention is one of the following proteins (a) and (b): (a) a protein composed of amino acid sequence as shown in Sequence 2 in a sequence table; and (b) a protein which is correlated with the plant lateral branch number and is derived from (a) after one or more amino acid residue substitution and/or deletion and/or addition of the amino acid sequence as shown in the Sequence 2 in the sequence table. It is proved through experiments that the cloned AtDOF 4.2 gene has a certain value of cultivating plant varieties with high lateral branch number, especially new species such as greening-related forest trees, flowers and lawn grass and the like.

Crystallization method for preparing amorphous esomeprazole magnesium salt

The invention relates to a crystallization method for preparing amorphous esomeprazole magnesium salt and belongs to the technical field of discovery and preparation of a medicine crystal form. The method comprises the following four steps: (1) mixing esomeprazole sodium salt, a water absorbent and ethanol at a suitable temperature according to a certain mass volume ratio; (2) adding ethanol solution of MgCl2*6H2O into the system to perform the reaction to obtain esomeprazole magnesium salt; (3) filtering to remove inorganic salt impurities and after concentrating filtrate, dropwise adding a proper quantity of dissolving agent acetonitrile; (4) washing the obtained precipitates by acetonitrile and carrying out vacuum drying to obtain the target product. By detection of analysis methods such as X-ray powder diffraction (PXRD), differential scanning calorimetry (DSC), infrared spectroscopy (IR) and the like, the target product is the amorphous esomeprazole magnesium salt and does not comprise ...

Disesquihydrate of esomeprazole magnesium salt and preparation method of disesquihydrate

The invention relates to a disesquihydrate of an esomeprazole magnesium salt and a preparation method of the disesquihydrate, belonging to the technical fields of discovery and preparation of drug crystal forms. The novel hydrate of the esomeprazole magnesium salt, prepared by the invention, is detected as the disesquihydrate of the esomeprazole magnesium salt through analysis methods such as thermal gravimetric analysis (TGA), powder X-ray diffraction (PXRD), differential scanning calorimetry (DSC), infrared spectroscopy (IR) and the like. Due to the preparation of the disesquihydrate of the esomeprazole magnesium salt, the basis is laid for the development and application of new dosage forms.

Method for rapidly correcting deformation of annular cooling machine trolley

The invention discloses a rapid correction method, and particularly relates to a method for rapidly correcting deformation of an annular cooling machine trolley, which belongs to the technical field of the maintenance and governing of metallurgic raw device. The invention provides a method for rapidly correcting the deformation of the annular cooling machine trolley, which is unnecessary for stopping the production in the process for correcting the deformation of the annular cooling machine trolley. The rapid correction method is characterized in that a standby pressure wheel is machined according to tilting deformation data of a trolley body counted in normal times, when leakage of the trolley appears, the deformation of the trolley can be corrected by directly replacing the pressure wheel which plays an adjustment role according to the detected tilting deformation situation of a trolley body causing the leakage.

Constant value remote setting maintenance-free system for transformer substation

The invention discloses a constant value remote setting maintenance-free system for a transformer substation. The system comprises a master station and at least one slave station, wherein the master station is connected with each slave station through an electric power data network or special line network; each slave station is connected with various relay protection devices downwards and communicates with the master station through a China Southern Power Grid 103 protocol upwards; and the master station sends a command to each slave station, the slave station converts the command received from the master station into a corresponding protocol command and sends the command to the relay protection devices, the relay protection devices send data to the slave station after receiving the command, and the slave station converts a data packet and sends the converted data packet to the master station. By the system, a model is maintenance-free, and production efficiency is greatly improved.

Method and system for remote operation of relay protection device constant values

The invention provides a method and a system for remote operation of relay protection device constant values. The method includes the steps that: after receiving a first up-sending instruction sent by a relay protection and fault information processing main-station, a relay protection and fault information processing sub-station transmits pre-stored configuration information of each relay protection device to the relay protection and fault information processing main-station, and the configuration information of each relay protection device includes control word constant value displaying manner information on an LCD (liquid crystal display) panel of each relay protection device; the relay protection and fault information processing main-station stores the configuration information of each relay protection device; after each relay protection device receives a second up-sending instruction sent by the relay protection and fault information processing main-station, the control word constant ...

Method for laminating thin molded laminate flooring by laminating device

The invention provides a method for laminating a thin molded laminate flooring by a laminating device. The laminating device is arranged on a hot press; the hot press is provided with an upper hot flat plate and a lower hot flat plate; the laminating device comprises an upper hot flat plate, a first copper net buffering pad, a first silica gel buffering pad, an upper steel plate, a laminate flooring blank, a lower steel plate, a second silica gel buffering pad, a second copper net buffering pad and a lower hot flat plate; and the method comprises the steps of mounting the laminating device, assembling the blank, laminating the blank, and the like. According to the invention, the problem that the thin laminate flooring blank is liable to be cracked in the laminating process is solved; and the method provided by the invention can be used for laminating the thin laminate flooring.

Multi-electromechanical-system distributed intelligent synchronous control device and method

The invention discloses a multi-electromechanical-system distributed intelligent synchronous control system. Operation state information is transmitted to a controller and an intelligent decision circuit through a detecting module; whether each part of a whole device is in fault is judged, a decision result is obtained; a certain controller in a controller set is then selected through an intelligent switching circuit to control an actuator to work; multiple electromechanical systems are communicated with each other, data are sent to the actuator; starting, stopping, speed reducing and steering tasks of the electromechanical systems are completed. Adjoining robot information is used for achieving multi-robot-system synchronous control, and synchronous control can be achieved without a robot kinetic model. The problem that in a real system, the robot kinetic model is not easy to obtain accurately, and practical interference affects the multi-robot system is avoided. Theoretical research of ...

Electric vibration test device with replaceable horizontal sliding tables

An electric vibration test device with replaceable horizontal sliding tables is characterized by comprising a stand, a vibration table and at least two horizontal sliding table components, wherein the vibration table is arranged at one end of the stand; a horizontal sliding table mounting area is arranged at the other end of the stand; fastener connecting holes are formed in the horizontal sliding table mounting area; the horizontal sliding table components comprise table tops, guide bearing mechanisms and fixing plates; fasteners corresponding to the fastener connecting holes in the horizontal sliding table mounting area are formed in the fixing plates of the horizontal sliding table components, so that the horizontal sliding table components are fixedly mounted in the horizontal sliding table mounting area in a replaceable manner by connection between the fasteners and the fastener connecting holes; and when the vibration table is turned into a horizontal position, a movable ring of the ...

Ground station of universalized configurable unmanned aerial vehicle

The invention discloses a ground station of a universalized configurable unmanned aerial vehicle, belonging to the technical field of unmanned aerial vehicle control. The ground station comprises a task planning module, a HOTAS (Hands on the Throttle and Stick) and pedal manipulation data acquisition module, a voice identifying and alarming module, an electronic flying information module and a multi-point touch module which are deployed on a computer A, and a flying information communication module, a training communication module, an aircraft adapting module, a databank module, a voice and video acquisition module and a 3D (Three-dimensional) view display module which are deployed on a computer B. On the basis that the psychological and physiological characteristics of a unmanned aerial vehicle manipulator are considered, the comprehensive problems of flying control and task control, and the problems of three-dimensional information sensation and fatigue caused by long-time operation are ...

Bioabsorbable semi-crystalline polymer for controlling release of drug from a coating

The present invention provides a semi-crystalline polymer for a coating on an implantable device for controlling release of drug and methods of making and using the same.

Intelligent online waveform recording system of distributing line

The invention discloses an intelligent online waveform recording system of a distributing line, which comprises three waveform collectors and a centralized processor. The three waveform collectors are respectively connected with three-phase current of the distributing line; the waveform collector comprises a current transformer, a signal processing circuit, a low-pass filter circuit, a first microprocessor and a first communication module; the first microprocessor is used for recording the present current change waveform according to current information when the first microprocessor judges that abrupt change of current of the distributing line happens according to the current information or timing is finished and sending current waveform information to the centralized processor through the first communication module; and the centralized processor performs centralized processing on the current waveform information of the three waveform collectors and obtains three-phase current information ...

Application of GmMYB73 in cultivating stress tolerance transgenic plants

The invention discloses an application of GmMYB73 in cultivating stress tolerance transgenic plants. The invention provides an application of GmMYB73 protein or an encoding gene thereof or following expression vectors in cultivating stress tolerance transgenic plants. In the application, the amino acid sequence of the GmMYB73 protein is a sequence 2 in a sequence list; and the nucleotide sequence of the encoding gene of the GmMYB73 protein is a sequence 1 in the sequence list. Experiments of the application prove that a transcription factor gene of an MYB family is cloned from soy, and researches discover that the over-expression of a GmMYB73 gene can be used for improving the stress tolerance of a transgenic plant, so that the GmMYB73 has important theoretical and practical significance in cultivating stress tolerance plant varieties and particularly cultivating new species such as abiotic stress resistance (salt tolerance) crops and forest grass, and can be used for cultivating and identifying ...

Genes conferring stress tolerance in plants and uses thereof

Compositions and methods for imparting stress tolerance to plants using WRKY nucleic acids and polypeptides.

Multi-cell mechanical simulation experiment platform

The invention provides a multi-cell mechanical loading device. The loading device comprises a piston of which the upper end is provided with a brace and a loading box of which one side is provided with an opening, wherein the specification of the piston is consistent with the internal specification of the loading box; the bottom of the loading box is provided with a sensor; and a signal acquisition instrument is arranged outside the loading box. The invention also provides a multi-cell mechanical simulation experiment platform. The experiment platform comprises the multi-cell mechanical loading device as mentioned above, a computer system and a universal material testing machine with a clamp, wherein the multi-cell mechanical loading device is fixed on the clamp; and the computer system is connected with the universal material testing machine. The invention has the following advantages: through the up-and-down movement of the piston, air is compressed to load pressure to cells, the stress ...

Transcriptional active protein AtPHD6 as well coding gene and application thereof

The invention discloses a transcriptional active protein AtPHD6 as well as a coding gene and application thereof. The protein provided by the invention is a protein with one of the following amino acid residue sequences: (a) a protein consisting of an amino acid sequence shown by a sequence 2 in a sequence table, and (b) a protein which is obtained by substituting and/or deleting and/or adding one or more amino acid residues on the amino acid sequence shown by the sequence 2 in the sequence table, is related to plant stress tolerance and is derived from the sequence 2. The transcriptional active protein AtPHD6 has an important value for culturing stress tolerance plant varieties in particular new varieties including abiotic stress tolerance (salt tolerance) crops, forest grasses and the like, can be used for culturing and identifying the stress tolerance plant varieties needed by agriculture and animal husbandry and ecological environmental control, and is of great significance for improving ...

Positioning and clamping mechanism of welding fixture of automobile stamping piece

The invention discloses a positioning and clamping mechanism of a welding fixture of an automobile stamping piece, which comprises an installing seat which is installed on a bottom board of the welding fixture; one end of the installing seat is provided with a locking cylinder, and the other end of the installing seat is fixed with a supporting block; a piston rod of the locking cylinder penetrates through the installing seat and the supporting block; a positioning pin which is positioned towards a positioning hole of the stamping piece is fixed on the extending end of the piston rod of the locking cylinder; the upper end of the installing seat is hinged with a bent pressing block; the lower end of the pressing block is buckled outside the supporting block; and a hinge mechanism is also fixed on the piston rod of the locking cylinder and is hinged with the upper end of the bent pressing block through a connecting rod. According to the invention, one locking cylinder is adopted for simultaneously ...

Application of synuclein gamma (SNCG) gene in diagnosis and hormone therapy of breast cancer

The invention relates to the application of synuclein gamma (SNCG) gene in diagnosis and hormone therapy of breast cancer, and the hormone therapy of breast cancer can be influenced by SNCG gene through adjusting the activated state of estrogen receptor (ER). The invention also relates to the application of the SNCG gene in the preparation of products for diagnosing the breast cancer. The invention has the advantages that the SNCG gene expression can be used for adjusting ER and hormone therapy sensibility, so that a new thought is created for the hormone therapy of the breast cancer; the SNCG gene expression can be used for adjusting ER and hormone therapy sensibility, so that the possibility of developing a new medicine for treating the breast cancer can be improved; and the SNCG gene can be used as a specific marker gene for diagnosing the breast cancer, so that the breast cancer can be more accurately and rapidly diagnosed.

Preparation method for folic acid-decorated and rare earth-modified carbon nano tube

The invention relates to a preparation method for a folic acid-decorated and rare earth-modified carbon nano tube. The method comprises the following steps: 1, soaking a carbon nano tube after functionalization processing into a rare earth modifying agent for 2-4 hours at room temperature, performing ultrasonic dispersion for 1-3 hours, filtering and drying; 2, using thionyl chloride to process the rare earth modified carbon nano tube obtained in step 1, so as to enable the functional group carboxyl on the rare earth modified carbon nano tube to be converted into acyl chloride, and grafting the obtained acylating chlorination carbon nano tube on a polymer polyethyleneglycol through an esterification reaction; and 3, adopting folic acid to perform decoration processing on the product obtained in step 2, so as to enable the product to have biocompatibility. Compared with the prior art, the preparation method has the advantages of no toxicity, excellent sensibilization performance, favorable ...

AMYLIN FAMILY PEPTIDES AND METHODS FOR MAKING AND USING THEM

The present invention relates to novel compounds having a function of a peptide in the amylin family, related nucleic acids, expression constructs, host cells, and processes production of the compounds. The compounds of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent metabolic disorders such as obesity, diabetes, and increased cardiovascular risk. 117-. (canceled)18. A method of treating eating disorders , insulin-resistance , obesity , abnormal postprandial hyperglycemia , diabetes of any kind , including Type I , Type II , and gestational diabetes , Metabolic Syndrome , Dumping Syndrome , hypertension , dyslipidemia , cardiovascular disease , hyperlipidemia , sleep apnea , cancer , pulmonary hypertension , cholecystitis , and osteoarthritis comprising administering to a subject in need thereof an effective amount of a peptide having at least 92% sequence identity to the amino acid sequence of SEQ ID NO: 137.19. The method of claim 18 , wherein the peptide having at least 92% sequence identity comprises the amino acid sequence of SEQ ID NO: 55 claim 18 , 67 claim 18 , 70 claim 18 , 73 claim 18 , 82 claim 18 , 83 claim 18 , 84 claim 18 , 89 claim 18 , 94 claim 18 , 100 claim 18 , 103 claim 18 , 106 claim 18 , 107 claim 18 , 111 claim 18 , 112 claim 18 , 125 claim 18 , 133 claim 18 , or 137.20. The method of claim 18 , wherein the peptide having at least 92% sequence identity comprises the amino acid sequence of SEQ ID NO: 137.21. The method of claim 18 , wherein the peptide is linked to a polyethylene glycol polymer claim 18 , a polyamino acid claim 18 , or a fatty acid.22. A method of treating eating disorders claim 18 , insulin-resistance claim 18 , obesity claim 18 , abnormal postprandial hyperglycemia claim 18 , diabetes of any kind claim 18 , including Type I claim 18 , Type II claim 18 , and gestational diabetes claim 18 , Metabolic Syndrome claim 18 , Dumping ...

Plant Stress Tolerance Related Protein GmSIK1 and Encoding Gene and Use Thereof

Provided are a plant stress tolerance related protein GmSIK1 and encoding gene and use thereof. The GmSIK1 protein has the amino acid sequence as shown in SEQ ID NO: 2. The transgenic plant with enhanced stress tolerance such as drought tolerance and/or salt tolerance can be obtained from introducing the encoding gene of GmSIK1 protein into plant cell. 1. A proteinselected from the group consisting off:(a) a protein consisting of amino acid residues 34-714 starting from an N-terminus of an amino acid sequence as shown in SEQ ID NO: 2;(b) a protein consisting of the amino acid sequence as shown in SEQ ID NO: 2;(c) a protein related to plant stress tolerance and derived from the protein of (a) by substituting and/or deleting and/or adding one or more amino acid residues in the amino acid sequence as shown in SEQ ID NO: 2; and(d) a protein related to plant stress tolerance and consisting of an amino acid sequence that is at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or at least 99% homologous with the amino acid sequence as shown in SEQ ID NO 2.2. An encoding gene of the protein according to .3. The encoding gene according to claim 2 , wherein the encoding gene is selected from the group consisting of 1) a DNA molecule comprising the nucleotide sequence of SEQ ID NO: 1;2) a DNA molecule that specifically hybridizes with the DNA molecule defined in 1) under stringent conditions and encodes a plant stress tolerance related protein; and3) a DNA molecule that is at least 70%, at least 75%, at least 80%, at least 85%, at least 90%, at least 95%, at least 96%, at least 97%, at least 98% or at least 99% homologous with the DNA sequence defined in 1) and encodes a plant stress tolerance related protein.4. A recombinant vector claim 2 , a recombinant bacterium claim 2 , a transgenic cell line claim 2 , or an expression kit comprising the encoding gene according to .5. A primer pair for amplifying a full-length or ...

Genes Conferring Drought and Salt Tolerance and Uses Thereof

Compositions and methods for conferring drought and salt tolerance to plants using tocopherol cyclase (TC) genes, including polynucleotides, polypeptides, vectors, cells and plants.

Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS

Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. 111-. (canceled)12. A method of forming a coating on an implantable medical device , comprising:a) forming a coating comprising nano- or micro-particles of a drug in crystalline or partially crystalline form onto at least a portion of an implantable medical device, andb) wrapping the implantable medical device on top of the coating comprising the nano- or micro-particles of the drug with a sheet of a polymer; andc) heating the sheet of the polymer at a temperature above the glass transition temperature of the polymer to form a coating comprising the polymer on top of the nano- or micro-particles of the drug.1321-. (canceled)22. The method of claim 12 , wherein the polymer is selected from the group consisting of poly(ethylene glycol terephthalate)-co-poly(butylene terephthalate) claim 12 , hyaluronic acid claim 12 , poly(ethylene glycol) claim 12 , phosphoryl choline claim 12 , poly(amide ester) (PEA) claim 12 , poly(d claim 12 ,l-lactide) (DLPLA) claim 12 , polyhydroxyalkanoate (PHA) claim 12 , polycaprolactone (PCL) claim 12 , poly(vinylidene fluoride) (PVDF) claim 12 , poly(hexafluoro propylene) (HFP) claim 12 , poly(ethylene vinyl alcohol) claim 12 , and combinations thereof.2327-. (canceled)28. The method of claim 22 , wherein the drug is selected from the group consisting of ABT-578™ claim 22 , paclitaxel claim 22 , docetaxel claim 22 , paclitaxel derivatives claim 22 , tacrolimus claim 22 , pimecrolimus claim 22 , batimastat claim 22 , mycophenolic acid claim 22 , estradiol claim 22 , clobetasol claim 22 , dexamethasone claim 22 , rapamycin claim 22 , 40-O-(2-hydroxy)ethyl-rapamycin (everolimus) claim 22 , 40-O-(3-hydroxy)propyl-rapamycin claim 22 , 40-O-(2-hydroxy)ethoxy]ethyl-rapamycin claim 22 , 40- ...

Methods of Forming Coatings with a Crystalline or Partially Crystalline Drug for Implantable Medical Devices using Sonocrystallization

Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided.

Methods of forming coatings with a crystalline or partially crystalline drug for implantable medical devices using supercritical fluid assisted sorption

Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. 1. A method of forming a coating comprising nano-particles or microparticles of a drug in slow-dissolving polymorph on an implantable device , comprising:a) applying to an implantable device a composition comprising a drug and a polymeric material to form a coating on the device, andb) inducing formation of a slow-dissolving polymorph of the drug by supercritical fluid assisted sorption and subsequent pressure swing to form nano-particles or microparticles of the drug in a slow-dissolving polymorph.2. The method of claim 1 , wherein the supercritical fluid used in the process is supercritical CO.3. The method of claim 1 , wherein the coated device is exposed to the supercritical fluid for a period of about 1 minute to about 2 hours such that the drug becomes crystalline having a crystallinity of about 1% to about 100%.4. The method of claim 1 , wherein the polymeric material is selected from the group consisting of poly(ethylene glycol terephthalate)-co-poly(butylene terephthalate) claim 1 , hyaluronic acid claim 1 , poly(ethylene glycol) claim 1 , phosphoryl choline claim 1 , poly(amide ester) claim 1 , poly(D claim 1 ,L-lactide) claim 1 , polyhydroxyalkanoate claim 1 , polycaprolactone claim 1 , poly(vinylidene fluoride) claim 1 , poly(hexafluoro propylene) claim 1 , poly(ethylene vinyl alcohol) claim 1 , and combinations thereof.5. The method of claim 4 , wherein the drug is selected from the group consisting of ABT-578™ claim 4 , paclitaxel claim 4 , docetaxel claim 4 , tacrolimus claim 4 , pimecrolimus claim 4 , batimastat claim 4 , mycophenolic acid claim 4 , estradiol claim 4 , clobetasol claim 4 , dexamethasone claim 4 , rapamycin claim 4 , 40-O-(2-hydroxy)ethyl-rapamycin (everolimus) claim 4 , 40-O-( ...

Methods of Forming Coatings with a Crystalline or Partially Crystalline Drug for Implantable Medical Devices

Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided. 1. A method of forming a coating on an implantable medical device , comprising:a) applying a powder of a drug in crystalline or partially crystalline form onto at least a portion of an implantable medical device;b) wrapping the implantable medical device on top of the drug with a sheet of a polymer; andc) heating the sheet of the polymer at a temperature above the glass transition temperature of the polymer to form a coating comprising the polymer on top of the drug.2. The method of claim 1 , wherein the powder of the drug comprises nano- or micro-particles of the drug.3. The method of claim 1 , wherein the polymer is selected from the group consisting of poly(ethylene glycol terephthalate)-co-poly(butylene terephthalate) claim 1 , hyaluronic acid claim 1 , poly(ethylene glycol) claim 1 , phosphoryl choline claim 1 , poly(amide ester) claim 1 , poly(D claim 1 ,L-lactide) claim 1 , polyhydroxyalkanoate claim 1 , polycaprolactone claim 1 , poly(vinylidene fluoride) claim 1 , poly(hexafluoro propylene) claim 1 , poly(ethylene vinyl alcohol) claim 1 , and combinations thereof.4. The method of claim 3 , wherein the drug is selected from the group consisting of ABT-578™ claim 3 , paclitaxel claim 3 , docetaxel claim 3 , tacrolimus claim 3 , pimecrolimus claim 3 , batimastat claim 3 , mycophenolic acid claim 3 , estradiol claim 3 , clobetasol claim 3 , dexamethasone claim 3 , rapamycin claim 3 , everolimus claim 3 , 40-O-(3-hydroxy)propyl-rapamycin claim 3 , 40-O-[2-(2-hydroxy)ethoxy]ethyl-rapamycin claim 3 , 40-O-tetrazole-rapamycin claim 3 , 4-amino-2 claim 3 ,2 claim 3 ,6 claim 3 ,6-tetramethylpiperidine-1-oxyl (4-amino-TEMPO) claim 3 , and combinations thereof.5. The method of claim 1 , wherein the crystallinity ...

USE OF POLYSACCHARIDES FROM RADIX ISATIDIS IN MANUFACTURE OF MEDICAMENTS AGAINST INFLUENZA VIRUS

A process of using root polysaccharide in the manufacture of medicaments for treating and/or preventing diseases induced by influenza virus and complications thereof, wherein the molecular weight of the root polysaccharide is 3000-7000 Da, and the influenza viruses include influenza virus A, influenza virus B, avian influenza virus, such as human influenza virus H1N1, H3N2, avian influenza virus H6N2, H7N3, H9N2 and INF B. The mechanism of the root polysaccharide against influenza virus is due to the ability to inhibit the attachment of influenza virus to the host cell. The present invention also discloses a pharmaceutical composition containing the above-mentioned root polysaccharides and a method for preparing the polysaccharides. 1IsatisIsatis. A process in preventing and/or treating diseases caused by influenza viruses and complications thereof , using root polysaccharide , wherein the molecular weight of the root polysaccharide is 3000-7000 Dalton.2IsatisRadix Isatidis. The process according to claim 1 , wherein the root polysaccharide is extracted from raw materials according to a method comprising:{'i': 'Radix Isatidis', 'A. decocting the raw materials by adding suitable times of distilled water to produce a decocted fluid, concentrating the decocted fluid to produce a concentrated solution so that the baume degree of which is 18-20° Bé at 50° C.;'}B. cooling the concentrated solution obtained in Step A to below 45° C., adding alcohol to produce an alcohol solution so that alcohol content is up to 60% or above 60% in the alcohol solution, allowing the alcohol solution to stand for more than 12 hours to precipitate;C. passing the alcohol solution through a macroporous resin column, eluting with pure water, and collecting an eluent;D. deproteinizing the eluent, and placing the deproteinized solution in a dialysis bag with a proper molecular weight to dialyse; and{'i': 'Isatis', 'E. evaporating the solution inside and/or outside the dialysis bag with a rotary ...

EXTENDED RELEASE BIODEGRADABLE OCULAR IMPLANTS

Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer. 141.-. (canceled)42. A method for making an extended release bioerodible implant for treating an ocular condition , the method comprising the steps of:(a) blending an active agent with a first bioerodible polymer;(b) extruding the blend of step (a) to form a filament;(c) breaking the extruded filament of step (b) into particles with a size of between about 30 μm and about 50 μm;(d) blending additional quantities of the active agent with a second bioerodible polymer;(e) mixing the particles of step (c) with the blend of step (d):(f) extruding the mixture of step (e) to form a filament;(g) cutting the filament of step (f) to form an extended release bioerodible implant for insertion into an ocular region for treating an ocular condition.43. The method of claim 42 , wherein the implant formed in step (g) has as diameter of about 0.05 mm to 3 mm and a length of about 0.5 to about 10 mm.44. The method of claim 42 , wherein the active agent is a steroidal anti-inflammatory agent.45. The method of claim 44 , wherein the active agent is dexamethasone.46. The method of claim 42 , wherein the active agent is dexamethasone claim 42 ,and wherein the first bioerodible polymer is selected from the group consisting of i) RG755, which is a poly(D,L-lactide-co-glycolide) having a molecular weight of about 40,000 and a lactide:glycolide content of about 75:25 by weight, ii) R203, which is a poly(D,L-lactide) having a molecular weight of about 14,000, iii) RG503, which is a poly(D,L-lactide-co-glycolide) having a molecular weight of about 28,000 and a lactide:glycolide content of about 50:50 by weight, iv) RG502, which is a poly(D,L-lactide-co-glycolide) having a molecular weight of about 11,700 and ...

Cross-Linked Peptides and Proteins, Methods of Making Same, and Uses Thereof

Cross-linked proteins and peptides, and methods of making and uses of such cross-linked proteins and peptides. The cross-linked proteins and peptides have rigid, distance-matching bismethylene aryl cross-linking moieties. Compositions comprising the cross-linked proteins and peptides can be used as pharmaceutical delivery formulations. The cross-linked proteins and peptides can have improved properties, such as cell permeability, as compared to the parent protein or peptide. 4) The cross-linked protein or peptide of claim 1 , wherein the two cysteines connecting the bismethylene aryl moiety are selected from the group consisting of L-cysteine claim 1 , D-cysteine claim 1 , α-methyl L-cysteine claim 1 , α-methyl D-cysteine claim 1 , and a combination thereof.5) The cross-linked protein or peptide of claim 1 , wherein one or both of the cross-linking cysteine residues is D-cysteine.6) The cross-linked protein or peptide of claim 1 , wherein Rand Rare hydrogen or methyl.7) The cross-linked protein or peptide of claim 1 , wherein the protein has at least one helical motif.8) The cross-linked protein or peptide of claim 1 , wherein the peptide is conjugated to a fluorophore.9) The cross-linked protein or peptide of claim 8 , wherein the fluorophore is fluorescein or fluorescein isothiocyanate (FITC).10) The cross-linked protein or peptide of claim 8 , wherein the fluorophore molecule is conjugated to the peptide through an aminohexanoic acid moiety.12) A composition comprising at least one cross-linked peptide or protein of and at least one excipient. This application claims priority to U.S. provisional patent application No. 61/459,569, filed Dec. 15, 2010, the disclosure of which is incorporated herein by reference.The present invention is related to cross-linked peptides and proteins, method of making such peptides and proteins, and uses of same. More particularly, the invention relates to peptides and proteins cross linked through cysteine and methylcysteine residues ...

LIQUID (METH)ACRYLIC SYRUP FOR IMPREGNATING A FIBROUS SUBSTRATE, METHOD OF IMPREGNATING A FIBROUS SUBSTRATE, COMPOSITE MATERIAL OBTAINED FOLLOWING POLYMERISATION OF THE PRE-IMPREGNATED SUBSTRATE

The present invention relates to a liquid (meth)acrylic syrup for impregnating a fibrous substrate. The present invention relates in particular to a viscous liquid syrup mainly containing methacrylic or acrylic components. The invention also relates to a process for manufacturing such a syrup. The invention also relates to a process for impregnating a fibrous substrate or long fibers with said viscous liquid syrup. The invention also relates to a fibrous substrate preimpregnated with said syrup, which is useful for manufacturing mechanical or structured parts or products. 1. A liquid (meth)acrylic syrup for impregnating a fibrous substrate , said fibrous substrate consisting of long fibers , wherein said syrup comprises:a) a (meth)acrylic polymer,b) a (meth)acrylic monomer, phosphorus-based additives such as phosphinates, diphosphinates, phosphonates, phosphates, red phosphorus, ammonium polyphosphates with a number of units n of at least 1000, and', 'hydrated mineral fillers such as metal hydroxides,, 'c) at least one flame-retardant substance chosen fromthe overall content of flame-retardant substance in said liquid (meth)acrylic syrup being less than 50% by weight, said liquid (meth)acrylic syrup having a dynamic viscosity of between 10 mPa·s and 10 000 mPa·s.3. The liquid (meth)acrylic syrup as claimed in claim 2 , wherein Rand Rare methyl claim 2 , ethyl claim 2 , n-propyl claim 2 , isopropyl claim 2 , n-butyl claim 2 , tert-butyl claim 2 , n-pentyl and/or phenyl groups.4. The liquid (meth)acrylic syrup as claimed in claim 2 , wherein Ris a methylene claim 2 , ethylene claim 2 , n-propylene claim 2 , isopropylene claim 2 , n-butylene claim 2 , tert-butylene claim 2 , n-pentylene claim 2 , n-octylene or n-dodecylene group; or a phenylene claim 2 , methylphenylene claim 2 , ethylphenylene claim 2 , tert-butylphenylene claim 2 , methylnaphthylene claim 2 , phenylmethylene claim 2 , phenylethylene claim 2 , phenylpropylene or naphthalene group.5. The liquid (meth) ...

ANTI-THEFT CABLE BOX

An anti-theft cable box includes a reel module, a conductive ring module, a coil spring module, an external connection module and an outer casing. The reel module includes an upper plate and a lower plate. A bottom surface of the upper plate is spaced from a top surface of the lower plate to form a cable groove between the upper plate and the lower plate. A cable is installed in the cable groove. The conductive ring module is disposed under the reel module, and the reel module is pivotally connected with the conductive ring module. The coil spring module is disposed under the conductive ring module. The external connection module includes an outer shell. The outer shell surrounds the coil spring module. The outer casing covers the reel module, the conductive ring module, the coil spring module and the external connection module. 1. An anti-theft cable box mounted on a display stand of electronic products , the anti-theft cable box comprising:a reel module including an upper plate, a lower plate and a cable, a middle of the upper plate protruding downward to form a hollow first barrel portion, a portion of a bottom surface of the hollow first barrel portion being recessed upward to form a first notch, a middle of the hollow first barrel portion having an accommodating space penetrating through the bottom surface of the hollow first barrel portion, a middle of the lower plate opening a circular first connecting hole vertically penetrating through the middle of the lower plate, the hollow first barrel portion of the upper plate being fixed in the first connecting hole, a bottom surface of the upper plate being spaced from a top surface of the lower plate to form a cable groove between the bottom surface of the upper plate and the top surface of the lower plate, the cable being installed in the cable groove, one end of the cable being connected with a connection plug, the other end of the cable being externally connected to an electronic device to be displayed;a ...

Multifunctional Castor

A multifunctional castor with steering, directional and brake functions and is provided with a mounting seat, a rotary seat, an engaging member, a wheel, a brake swing member, a longitudinal rod assembly, an engaging assembly, a transverse rod, a brake pedal and a brake-release pedal. Pressing down or pushing up the brake pedal can activate the steering, direction and brake functions of the castor, and then the steering, direction and brake functions of the castor can be deactivated by controlling the brake-release pedal. 1. A multifunctional castor comprising:a mounting seat with a shaft portion;a rotary seat rotatably mounted on the mounting seat and having a pivot portion pivoted to the shaft portion;an engaging member fixed in the rotary seat and including an engaging hole and an engaging tooth;a wheel rotatably disposed on the rotary seat and including a wheel toothed portion;a brake swing member including a brake pivot portion pivoted to the rotary seat, a brake press portion located at one side of the brake pivot portion, and a brake toothed portion located at another side of the brake pivot portion and used to engage with or disengage from the wheel toothed portion;a longitudinal rod assembly disposed in the shaft portion and the rotary seat in such a manner that the longitudinal rod assembly is moveable along an axial direction of the shaft portion and includes: a first end, a second send abutting against the brake press portion, and a first shoulder portion and a second shoulder portion between the first and second ends;an engaging assembly disposed between the first and second shoulder portions of the longitudinal rod assembly and including a protruding engaging portion for engaging with or disengaging from the engaging hole of the engaging member, and an engaging toothed portion for engaging with or disengaging from the engaging tooth of the engaging member;a transverse rod inserted in the shaft portion and including a push portion for pushing against ...

WOUND HEALING VIA AUTOLOGOUS STEM CELL MOBILIZATION

The present invention relates to the field of wound healing. More specifically, the present invention provides methods and compositions useful for improved wound healing via autologous stem cell mobilization. In one embodiment, a method for improving wound healing in a patient comprises administering to the patient a therapeutically effective amount of a stem cell mobilizer and a low dose of an immunosuppressive agent. 1. A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and an immunosuppressive agent.2. The method of claim 1 , wherein the stem cell mobilizer is selected from the group consisting of AMD3100 claim 1 , AMD3465 claim 1 , TG-0054 claim 1 , BKT140 claim 1 , G-CSF claim 1 , GM-CSF claim 1 , SDF-1 claim 1 , and SCF.3. The method of claim 1 , wherein the stem cell mobilizer is a CXCR4 antagonist.4. The method of claim 3 , wherein the stem cell mobilizer is AMD3100.5. The method of claim 1 , wherein the immunosuppressive agent is selected from the group consisting of Tacrolimus claim 1 , cyclosporine claim 1 , Orthoclone OKT3 claim 1 , mycophenolate claim 1 , and sirolimus.6. The method of claim 5 , wherein the immunosuppressive agent is Tacrolimus.7. The method of claim 1 , wherein the immunosuppressive agent is administered in a low dose amount.8. The method of claim 1 , wherein the stem cell mobilizer and the immunosuppressive agent are the same compound.9. A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and a low dose of an immunosuppressive agent.10. A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of AMD3100 and a low dose of Tacrolimus.11. The method of claim 10 , wherein the low dose of Tacrolimus is in the range of about 0.01 mg/kg to about 0.05 mg/kg.12. A method for ...

TITANIUM ALLOY PRODUCT, HOUSING, AND METHOD FOR MANUFACTURING THE SAME

A titanium alloy product includes a titanium alloy substrate and a plurality of first holes defined in a surface of the titanium alloy substrate. The first holes have an opening on the surface of the titanium alloy substrate and an inner wall connecting with the opening, a diameter of the inner space is greater than a diameter of the opening. The product tensile strength of bonding between the titanium alloy product and a material part filled in the first holes is very high. A housing with the titanium alloy product and a method for manufacturing the titanium alloy product are also disclosed. 1. A titanium alloy product , comprising:a titanium alloy substrate; anda plurality of first holes defined in a surface of the titanium alloy substrate;wherein at least one of the plurality of first holes has an opening on the surface of the titanium alloy substrate and an inner wall connecting with the opening, a longest segment of two points on a periphery of the opening is defined as segment A;a longest segment of two points on the inner wall is defined as segment B;a plane A defined by segment A and a point not on segment A but on the periphery of the opening is parallel to a plane B defined by segment B and a point not on segment B but on the inner wall;a length of segment B is greater of a length of segment A.2. The titanium alloy product of claim 1 , wherein the titanium alloy product further comprises a plurality of second holes disposed on an inner wall of the plurality of first holes claim 1 , the inner wall of the plurality of first holes is further recessed to form the plurality of second holes claim 1 , at least one of the plurality of the second hole comprises a main body and a plurality of spikes claim 1 , the plurality of spikes is formed radially on the main body; and the plurality of the second holes is formed radially in the inner wall of at least one of the plurality of the first holes.3. The titanium alloy product of claim 1 , wherein a range of a median ...

EXTENDED RELEASE BIODEGRADABLE OCULAR IMPLANTS

Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer. 1. A method for treating an ocular condition , the method comprising implanting into an ocular site a drug delivery system comprising: (i) an active agent, and;', '(ii) a bioerodible polymer,, '(a) at least one bioerodible implant suitable for insertion into an ocular region or site, the bioerodible implant comprising;'}wherein the bioerodible implant can release a therapeutic level of the active agent at a substantially continuous rate upon insertion into an ocular region or site for a period time between about 30 days and about 1 year.2. The method of claim 1 , wherein the drug delivery system comprises a first and a second bioerodible implant wherein the first bioerodible implant comprises a first active agent and a first bioerodible polymer and wherein the second bioerodible implant comprises a second active agent and a second bioerodible polymer.3. The method of claim 1 , wherein the drug delivery system comprises a first claim 1 , a second claim 1 , and a third bioerodible implant claim 1 , wherein the first bioerodible implant comprises a first active agent and a first bioerodible polymer and wherein the second bioerodible implant comprises a second active agent and wherein the third bioerodible implant comprises a third active agent and a third bioerodible polymer.4. The method of claim 3 , wherein the first claim 3 , the second and the third active agent are the same.5. The method of claim 4 , wherein the first claim 4 , the second and the third active agent is dexamethasone.6. The method of claim 1 , wherein the ocular site is the vitreous of the eye.7. The method of claim 6 , wherein the implanting into the ocular site is by a scieral incision.8. The method of claim 7 , ...

Antibody targeted to tissue factor, preparation method therefor, and use thereof

The present invention provides a tissue factor (TF) monoclonal antibody and a preparation method therefor. The monoclonal antibody provided by the present invention can specifically bind with a TF antigen, has high affinity and low immunogenicity, and has the activity of resisting tumors and the like.

EXTENDED RELEASE BIODEGRADABLE OCULAR IMPLANTS

Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer. 1. An extended release bioerodible implant for treating an ocular condition in a subject , the implant made by a method comprising the steps of:(a) blending an active agent with a first bioerodible polymer;(b) extruding the blend of step (a) to form a filament;(c) breaking the extruded filament of step (b) into particles with a size of between about 30 p.m and about 50 μm;(d) blending additional quantities of the active agent with a second bioerodible polymer;(e) mixing the particles of step (c) with the blend of step (d):(f) extruding the mixture of step (e) to form a filament;(g) cutting the filament of step (f) to form an extended release bioerodible implant for insertion into an ocular region or site of the subject.2. The implant of claim 1 , wherein the implant formed in step (g) has a diameter of about 0.05 mm to about 3 mm and a length of about 0.5 to about 10 mm.3. The implant of claim 1 , wherein the active agent is a steroidal anti-inflammatory agent.4. The implant of claim 1 , wherein the active agent is dexamethasone.5. The implant of claim 1 , which when administered into the ocular region or site of the subject claim 1 , releases a therapeutic level of the therapeutic agent into the ocular region or site for a period of time of between about 30 days and about 1 year.6. The implant of claim 1 , wherein:the active agent is dexamethasone;the first bioerodible polymer is selected from the group consisting of i) RG755, which is a poly(D,L-lactide-co-glycolide) having a molecular weight of about 40,000 and a lactide:glycolide content of about 75:25 by weight, ii) 8203, which is a poly(D,L-lactide) having a molecular weight of about 14,000, iii) RG503, which is a poly(D,L- ...

METHODS OF RECRUITING SDF-PRODUCING MACROPHAGES

The present invention relates to the field of wound healing. More specifically, the present invention provides methods and compositions useful for improved wound healing via autologous stem cell mobilization. In one embodiment, a method for improving wound healing in a patient comprises administering to the patient a therapeutically effective amount of a stem cell mobilizer and a low dose of an immunosuppressive agent. 1. A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and an immunosuppressive agent.2. The method of claim 1 , wherein the stem cell mobilizer is selected from the group consisting of AMD3100 claim 1 , AMD3465 claim 1 , TG-0054 claim 1 , BKT140 claim 1 , G-CSF claim 1 , GM-CSF claim 1 , SDF-1 claim 1 , and SCF.3. The method of claim 1 , wherein the stem cell mobilizer is a CXCR4 antagonist.4. The method of claim 3 , wherein the stem cell mobilizer is AMD3100.5. The method of claim 1 , wherein the immunosuppressive agent is selected from the group consisting of Tacrolimus claim 1 , cyclosporine claim 1 , Orthoclone OKT3 claim 1 , mycophenolate claim 1 , and sirolimus.6. The method of claim 5 , wherein the immunosuppressive agent is Tacrolimus.7. The method of claim 1 , wherein the immunosuppressive agent is administered in a low dose amount.8. The method of claim 1 , wherein the stem cell mobilizer and the immunosuppressive agent are the same compound.9. A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of a stem cell mobilizer and a low dose of an immunosuppressive agent.10. A method for improving wound healing in a patient comprising administering to the patient a therapeutically effective amount of AMD3100 and a low dose of Tacrolimus.11. The method of claim 10 , wherein the low dose of Tacrolimus is in the range of about 0.01 mg/kg to about 0.05 mg/kg.12. A method for ...

EXTENDED RELEASE BIODEGRADABLE OCULAR IMPLANTS

Biodegradable implants sized and suitable for implantation in an ocular region or site and methods for treating ocular conditions. The implants provide an extended release of an active agent at a therapeutically effective amount for a period of time between 50 days and one year, or longer. 2. The drug delivery system of claim 1 , wherein the drug delivery system comprises:(a) a first implant with a first release characteristic, and;(b) a second implant with a second release characteristic, wherein the first and second release characteristics differ.3. The drug delivery system of claim 2 , wherein the release profile of the drug delivery system corresponds to the sum of the first and second release profiles.4. The drug delivery system of claim 1 , wherein the drug delivery system comprises:(a) a first implant with a first release characteristic,(b) a second implant with a second release characteristic, and;(c) a third implant with a third release characteristic.5. The drug delivery system of claim 4 , wherein the release profile of the drug delivery system corresponds to the sum of the first claim 4 , second and third release profiles.6. The drug delivery system of claim 1 , wherein the drug delivery system comprises at least two different implants which have different bioerodible polymers.7. The drug delivery system of comprising first claim 4 , second and third bioerodible implants claim 4 , whereinthe first implant comprises a first polymer with a first average molecular weight; the second implant comprises a second polymer with a second average molecular weight, andthe third implant comprises a third polymer with a third average molecular weight.8. The drug delivery system of claim 1 , wherein the active agent is an anti-inflammatory compound.9. The drug delivery system of claim 1 , wherein the active agent is an anti-angiogenesis compound.10. A drug delivery system for treating an ocular condition comprising; (i) an anti-inflammatory drug, and;', '(ii) a ...

PEPTIDE-PEPTIDASE INHIBITOR CONJUGATES AND METHODS OF USING SAME

Peptide-peptidase inhibitor conjugate molecules are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions. Such diseases, conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, and other diabetes-related disorders. 1. A peptide-peptidase inhibitor conjugate comprising a peptide covalently linked to a peptidase inhibitor.2. The conjugate according to claim 1 , wherein the peptide is selected from the group consisting of a GLP-1 peptide claim 1 , a GIP peptide claim 1 , a GLP-2 peptide claim 1 , an exendin claim 1 , a PYY peptide claim 1 , an amylin peptide claim 1 , a calcitonin claim 1 , a leptin and analogs or hybrids thereof.3. The conjugate according to claim 1 , wherein the peptidase inhibitor is selected from the group consisting of a vasopeptidase inhibitor claim 1 , an angiotensin converting enzyme inhibitor claim 1 , an endothelial converting enzyme inhibitor claim 1 , a human endopeptidase inhibitor claim 1 , a dipeptidyl peptidase IV (DPP-IV) inhibitor an aminopeptidase inhibitor claim 1 , a cysteine protease inhibitor claim 1 , a serine protease inhibitor claim 1 , and a carboxypeptidase inhibitor.4. The conjugate according to claim 2 , wherein the peptide is GLP-1 or an analog of GLP-1 comprising a sequence as set forth in any one of SEQ ID NOs: 41-59.5. The conjugate according to claim 2 , wherein the peptide is GIP or an analog of GIP comprising a sequence as set forth in any one of SEQ ID NOs: 74-88 or 293-295.6. The conjugate according to claim 1 , wherein the peptide-peptidase inhibitor conjugate is synthesized chemically or recombinantly.7. The conjugate according to claim 1 , wherein the plasma half-life of the conjugate is greater than the plasma half-life of the peptide not conjugated to the peptidase ...

RESPONSIVE APPLICATION TASK MANAGEMENT

A system may detect a quit operation corresponding to a child application. In response to detection the quit operation, the system may store, in a memory, a mapping between the child application identifier and the child application task, and suspend display of the child application. The system may generate a foreground and background switching entry corresponding to the child application, the foreground and background switching entry associated with the child application identifier. The system may display the foreground and background switching entry in a visible region of the graphical user interface generated based on a parent application. The system may detect a selection operation indicative of the foreground and background switching entry. In response to the selection operation, the system may obtain the child application task from the memory according to the child application identifier, and resume display of the child application based on the child application task. 1. A method comprising:displaying, on a graphical user interface, content generated by a child application of a parent application;detecting a quit operation corresponding to a child application; obtaining a child application identifier of the child application and a child application task corresponding to the child application identifier,', 'storing, in a memory, a mapping between the child application identifier and the child application task, and', 'hiding the content generated by the child application;, 'in response to detecting the quit operationgenerating a foreground and background switching entry corresponding to the child application, the foreground and background switching entry associated with the child application identifier;displaying the foreground and background switching entry on a parent application region of the graphical user interface;detecting a selection operation indicative of selection of the foreground and background switching entry; and obtaining the child application ...

Cable assembly

The present invention includes a cable having a plurality of conducting wires; a circuit board arranged at a front of the cable, the conducting wires of the cable being soldered at a rear of the circuit board; a connector arranged at a front of the circuit board and having a plurality of terminal slots; a plurality of terminals secured in the terminal slots to connect to the front of the circuit board with its rear end. The circuit board joined between the cable and the connector in this invention is configured to control the resistance, besides it also benefits the soldering of the cable and the contactor and reduces the yield loss due to the solder paste applied in the SMT process; and the requirements of high frequency specifications can also be satisfied by the circuit arranged on the circuit board.

Soft segmentation based rules optimization for zero detection loss false positive reduction

A system and method includes soft-segment based rules optimization that can mitigate the overall false positives while maintaining 100% true positive detection. The soft clustering allows real-time re-assignment of an account to a dominate archetype behavior, as well as rule optimization based on a logical order with more relaxation on thresholds for the most inefficient rules is performed within each archetype. The rule optimization provides false positive reduction compared to a baseline rule system. The method can be used to reduce false positives for any rule-based detection system in which the same true positive detection is required.

Purification of polymers for coating applications

Various embodiments of methods and devices for coating stents are described herein. Among these embodiments are methods of manufacturing an implantable medical device by purifying a polymer with a fluid capable of swelling the polymer, and subsequently coating a device with the purified polymer or fabricating a device from the purified polymer. A preferred polymer is poly(vinylidene fluoride-co-hexafluoropropylene).

Methods of recruiting SDF-producing macrophages

The present invention relates to the field of wound healing. More specifically, the present invention provides methods and compositions useful for improved wound healing via autologous stem cell mobilization. In one embodiment, a method for improving wound healing in a patient comprises administering to the patient a therapeutically effective amount of a stem cell mobilizer and a low dose of an immunosuppressive agent.

Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS

Methods for making coatings on an implantable device such as a drug-eluting stent comprising a polymer and nano or microparticles of a drug in slow-dissolving polymorph, implantable devices produced by the methods and methods of using the coatings are provided.

Rotary dehydrating tub for mop

Antibody targeted to tissue factor, preparation method therefor, and use thereof

The present invention provides a tissue factor (TF) monoclonal antibody and a preparation method therefor. The monoclonal antibody provided by the present invention can specifically bind with a TF antigen, has high affinity and low immunogenicity, and has the activity of resisting tumors and the like.

Shock isolation cushion

A shock isolation cushion has two basal components and at least one shock isolation tier. The two basal components are disposed at an interval. The at least one shock isolation tier is disposed between the two basal components and is sequentially stacked from one of the two basal components to the other one of the two basal components. Wherein each of the at least one shock isolation tier has multiple shock isolation units. Each of the multiple shock isolation units has a supporting section and at least two buffering sections. The at least two buffering sections respectively extend from two opposite ends of the supporting section. Each of the at least two buffering sections is curved to form an opening between the buffering section and the supporting section.

LIQUID (METH) ACRYLIC SYRUP FOR IMPREGNATING A FIBROUS SUBSTRATE, METHOD FOR IMPREGNATING A FIBROUS SUBSTRATE, COMPOSITE MATERIAL OBTAINED AFTER POLYMERIZATION OF SAID PRE-IMPREGNATED SUBSTRATE.

Embedded tablet PC for replacing Ethernet power supply module

LIQUID (METH) ACRYLIC SYRUP FOR IMPREGNATING A FIBROUS SUBSTRATE, METHOD FOR IMPREGNATING A FIBROUS SUBSTRATE, COMPOSITE MATERIAL OBTAINED AFTER POLYMERIZATION OF SAID PRE-IMPREGNATED SUBSTRATE.

La présente invention concerne un sirop (méth)acrylique liquide d'imprégnation d'un substrat fibreux. La présente invention concerne en particulier un sirop liquide visqueux contenant principalement des composants méthacryliques ou acryliques. L'invention concerne également un procédé de fabrication d'un tel sirop. L'invention concerne en outre un procédé d'imprégnation d'un substrat fibreux ou de fibres longues avec ledit sirop liquide visqueux. L'invention concerne également un substrat fibreux pré-imprégné avec ledit sirop qui est utile pour la fabrication de pièces ou produits mécaniques ou structurés. La présente invention concerne également un procédé de fabrication pour la fabrication de pièces ou d'articles mécaniques ou structurés et des pièces mécaniques ou structurées tridimensionnelles obtenues par ce procédé. L'invention s'applique à la réalisation de pièces mécaniques ou d'éléments stucturels en matériau composite thermoplastique résistant au feu.

Linear single chain recombinant anti-cea/cd3/cd28 trispecific antibody

This invention refers to a linear single chain recombinant trispecific antibody (scTsAb). This trispecific antibody is composed of an anti-carcinoembryonic antigen (CEA), an anti-CD3, and an anti-CD28 (CEA-scTsAb). More specifically, a Fc linking peptide fuses the anti-CEA single chain fragment (scFv) to the anti-CD3 scFv, and an HSA linking peptide fuses the anti CD3 scFv to the anti-CD28 heavy variable chain (V H) in tandem. A c-myc-tag and/or (His) 6-tag is attached to the C terminal of the CEA-scTsAb either alternatively or simultaneously. This invention also refers DNA sequence coding for the said scTsAbs, plasmids containing the said sequences, and host cells containing the said plasmids. These invented scTsAbs are intended for use in the development of therapeutic drug candidate for treatment of human colon cancer.

Peptide-Peptidase Inhibitor Conjugates and Methods of Using Same

Peptide-peptidase inhibitor conjugate molecules are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions. Such diseases, conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, and other diabetes-related disorders.

Capacitive touch panel with two-layer printed circuit board

Systems and Methods for Wireless Communications

A method to improve TCP throughput by separating TCP acknowledgment flow from TCP normal data flow in a wireless communications environment. This method creates dedicated signaling air interface link and signaling A10 link for TCP acknowledgment flow and assigns a higher priority value to TOS field of IP packets encapsulating TCP acknowledgments than those encapsulating TCP normal data.

Extended release biodegradable ocular implant

【課題】 眼疾患、例えば後眼疾患の治療のために、長期間、所望の後眼領域または部位において治療薬剤レベルを維持できるように、治療用薬剤を送達できる治療用薬剤送達システムを提供する。 【解決手段】 眼領域または部位に挿入するのに適した少なくとも1つの生侵食性インプラントを含んで成る眼疾患の治療用薬剤送達システムであって、生侵食性インプラントが、（i）活性剤、および（ii）生侵食性ポリマーを含んで成り、生侵食性インプラントが、治療レベルの活性剤を眼領域または部位に30日〜1年の期間にわたって放出することができる、薬剤送達システム。 【選択図】なし

Amylin family peptides and methods for making and using them

Provided is a specified amylin family peptide and its variants as well as their use in the manufacture of medicaments for treating eating disorders, diabetes, cardiovascular diseases and other diseases. (62) Divided Out of 549332

Lower limb exercise auxiliary device

一種下肢運動輔助裝置，包括一基座、一腳踏曲柄機構、一固定機構及一電控部。該腳踏曲柄機構設置於該基座上，該固定機構樞接於基座，該電控部用以驅動腳踏曲柄機構。此裝置可擺放於地面、床上或者藉由該固定機構與輪椅連接供使用者對該腳踏曲柄機構進行踩踏，所述使用者包括一般人或者腳部活動度不佳的人，使用時可選擇由電控部自動控制踩踏動作或者選擇由人自主性的踩踏，前者可被動的訓練腳部關節(包括髖、膝及踝關節)的活動度，後者可做肌力訓練。在踩踏前或踩踏過程中，可隨時調整踩踏的速度、時間及方向。

Elastic non-metal clip and assembled fence including the same

An assembled fence includes a transverse bar, a vertical bar and a clip, wherein the clip is an elastic non-metal clip. Due to the installation of the elastic non-metal clip, all fence parts, including the clip, can be assembled in the assembly site; the clip which does not need to be assembled in the vertical bar in advance will not be damaged and is free from a problem of scratching other parts such as the vertical bar in a transportation process; and the non-metal clip is low in cost.

Input module and electronic device thereof

Antibody targeted to tissue factor, preparation method therefor, and use thereof

Key free mouse device

A mouse device includes an upper cover, an intermediate cover, a lower cover, a circuit board, and two switches. Two protrusion posts of the upper cover are respectively penetrated through two perforations of the intermediate cover. Two first pivotal parts of the upper cover are respectively connected with two second pivotal parts of the intermediate cover. The upper cover is fixedly connected to an annular sidewall of the lower cover. The circuit board and the two switches are disposed on the lower cover. When the upper cover is rotated relative to the intermediate cover through the two first pivotal parts and two second pivotal parts, one of the two switches is triggered by the corresponding protrusion post so as to generate a corresponding electronic signal. The use of the present mouse device can prevent from introducing foreign matters, reduce the depressing force and avoid erroneously triggering the switch.

Method and system for admission and congestion control of network communication traffic

A method for controlling communications traffic on an inter-access-network link includes receiving a request for transmission of a traffic flow and determining a priority queue associated with the traffic flow. If the priority queue corresponds to the one of a first plurality of priority levels, the method further includes determining whether one or more predetermined criteria for the traffic flow are satisfied. If yes, the method additionally admitting the traffic flow, storing information associated with the traffic flow in the queue, and transmitting information associated with the traffic flow from the queue based on at least a strict priority process. If the queue corresponds to the one of a second plurality of priority levels, the method further admitting the traffic flow, storing information associated with the traffic flow in the queue, and transmitting information associated with the traffic flow from the queue based on at least an arbitrated priority process.

Lens of sun glasses and buckle structure of frame

Manufacturing apparatus for water-repellant fabric structure

Improvement of smoke shaft wall for joss paper incinerator

Medical absorbing article

一種醫療吸收用品，包含：一吸收本體，及至少一顯示標籤。該吸收本體用以覆蓋於傷口上以吸收傷口滲液。該顯示標籤設置於該吸收本體中並部分凸伸出該吸收本體，且依據該吸收本體所吸附滲液狀態而改變顏色。藉由觀察該顯示標籤的顏色變化，可以得知該吸收本體是否以吸附過多的滲液而飽和或是了解傷口的狀況。

Network TV and multimedia real-time broadcasting system

Biochemical reactor

Adaptive frame structure for TDD point-to-point wireless transmission

The present invention relates to an arrangement for point-to-point transmission over links between first and second link (end) terminals in a system implementing time division duplex (TDD) and wherein information is sent over the links in frames divided into time slots. It is adapted to determine the lengths of the frames on a per link basis using one or more link parameters, the frame length hence being variable.

Composition and methods for treatment of congestive heart failure

Biochemical reactor

Heat dissipation patch

Peptide-peptidase inhibitor conjugates and methods of using same

Peptide-peptidase inhibitor conjugate molecules are disclosed. These conjugate molecules are useful as agents for the treatment and prevention of metabolic and cardiovascular diseases, disorders, and conditions. Such diseases, conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, insulin-resistance, obesity, and diabetes mellitus of any kind, and other diabetes-related disorders.

Optical fiber line organizing device

一種光纖整線裝置，包含一導引單元，及至少一滑動地設置於該導引單元上的定位單元。該定位單元包括一滑動地設置於該導引單元上的本體、一由該本體向外延伸的第一定位機構、一與該第一定位機構相間隔且同方向地由該本體向外延伸的第二定位機構，及一由該本體、該第一定位機構與該第二定位機構相配合界定出的定位槽。利用與光纖導線之直徑相配合的定位槽，再配合該第一定位機構與該第二定位機構，不但能迅速地將光纖導線依設定順序定位於該定位槽中，也能避免定位於該定位槽中所述光纖導線因施力大小不一而發生損壞，或是位置順序發生錯置的情形。

Fabric curtain blind forming machine

Biochemical reactor of which the lens used for converging the test tube fluorescent can quickly eliminate fogging phenomenon and is not deformed under heat

本發明是一種生化反應器，用以容置多數試管，其包含有一外殼、一試管架、一固定座、一透鏡座以及一菲涅耳透鏡，該試管架、固定座、透鏡座、菲涅耳透鏡均設於該外殼內部，該試管架用以供該等試管置放，該固定座位於該試管架下方且具有多數位置與該等試管對應的通孔，該透鏡座位於該固定座下方，並具有一頂板、以及多數位於該頂板且位置與該等試管對應的穿孔，該菲涅耳透鏡夾設於該透鏡座之頂板與該固定座之間，故不易因受熱而變形，且該菲涅耳透鏡厚度薄體積小，即便其中一側受熱起霧，菲涅耳透鏡在短時間內便受熱均勻，因此霧氣很快就會消散。

Method of displaying multiple images formed from pixels

A method of displaying multiple images formed from pixels, including the steps of providing a plurality of raw images, extracting a utility image zone for each of the raw images, and dividing the utility image zone of each of the raw images into a plurality of image pixels, for each of the image pixels of each of the utility image zones establishing a plurality of pixel arrays arranged to distribute in a predetermined orientation, providing a raw canvas, dividing the canvas into a plurality of canvas pixels, and for each of the canvas pixels, establishing a plurality of canvas pixel matrixes arranged with respect to the predetermined orientation of the pixel arrays, adjusting sizes of the image pixels of the utility image zones equal to sizes of the canvas pixels of the raw canvas respectively, superimposing the image pixel arrays onto the canvas pixel arrays respectively in a predetermined order to form a multiple image canvas, providing a plurality of filtering grids in such a manner that the filtering grids are capable of sliding along the multiple image canvas so as to selectively block and display the image pixels, and providing illumination to the multiple image canvas for display advertising images.

Biodegradable ocular implants with long-term release characteristics

The present invention provides a bioerodible implant for treating an ocular condition, the implant comprising (a) a dispersion comprising an active agent dispersed with a first bioerodible polymer, and (b) a particle comprising the active agent and a second bioerodible polymer, wherein the particle has an active agent release characteristic which differs from the active agent release characteristic of the dispersion (continued release period of 50d to 1y). In addition, the invention provides a bioerodible implant for treating a posterior ocular condition, the bioerodible implant comprising (a) a first region containing a first mixture of an active agent and a first bioerodible polymer, and (b) a second region containing a second mixture of the active agent and a second bioerodible polymer, wherein the first and second regions have different active agent release characteristics. Corresponding methods for producing bioerodible implants are also provided.

Composition and methods for treatment of congestive heart failure

Provided herein is the use of GLP-1 molecules or agonists and analogs thereof, and the use of exendin molecules or agonists and analogs thereof, including their derivatives and active fragments, for the prevention or treatment of congestive heart failure. Pharmaceutical compositions for use in the methods described herein are also disclosed. Further provided are compositions and methods for the treatment and/or prevention of diabetes mellitus, hyperglycemia, insulin resistance and obesity, and for the reduction of food intake and suppression of appetite of subjects.

Lamellar stacked solid electrolytic condenser

Bidirectional antenna tracking system with vehicle attitude compensation

High-pressure valve module

Bus applicable to solar cell assembly

Controller for use in resonant direct current/direct current converter

Biological sludge for the production of biomass fuels

Cable connector assembly

Wound healing via autologous stem cell mobilization

The present application relates to therapeutically effective amount of a stem cell mobilizer and Rapamycin for use as a medicament for improving wound healing in a patient.

Motor stator and wire tying device thereof

本發明為一種馬達定子及其結線裝置，其包含有一鐵心，於鐵心內側間隔設有複數線圈繞組，並於鐵心一側設置結線裝置，結線裝置包含有複數連接片及一外框體，各連接片為金屬導體且包含有一弧片段及至少一導接部，該等弧片段呈長窄形薄片狀且沿長軸向彎曲呈圓弧形，該等導接部分別連接該等線圈繞組，其中數片連接片供連接電源，該外框體包覆該等連接片並分隔該等連接片，本發明藉由模組化的結線裝置之設計，能夠簡易的安裝連接各線圈繞組，且在不增加馬達定子整體厚度的情況下，提供更大的電流量通過，而可適用於大功率之馬達規格。

Waterproof and dustproof protection device for mobile phone

Dust collection drum

Can reduce the noise and wear less gear difference reducer

Composition and methods for treatment of congestive heart failure

Provided herein is the use of GLP-1 molecules or agonists and analogs thereof, and the use of exendin molecules or agonists and analogs thereof, including their derivatives and active fragments, for the prevention or treatment of congestive heart failure. Pharmaceutical compositions for use in the methods described herein are also disclosed. Further provided are compositions and methods for the treatment and/or prevention of diabetes mellitus, hyperglycemia, insulin resistance and obesity, and for the reduction of food intake and suppression of appetite of subjects.

Improvement of helmet structure

Amylin family peptides and methods for making and using them

The present invention relates to novel compounds having a function of a peptide in the amylin family, related nucleic acids, expression constructs, host cells, and processes production of the compounds. The compounds of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent metabolic disorders such as obesity, diabetes, and increased cardiovascular risk.

Uses of unsaturated fatty acids for inhibiting virus replication and /or infection

Uses of unsaturated fatty acid linoleic acid and docosenoic acid or pharmaceutically acceptable salts or esters thereof for inhibiting hepatitis C virus replication or preventing and/or treating hepatitis C virus inflection are disclosed.

Pivot joint that is light to open and heavy to close

Dryer

Power factor correction controller, controlling method thereof, and electric power converter using the same

A power factor correction controller is utilized for a power factor correction circuit in a critical conduction mode of an electric power converter. The power factor correction controller generates a control voltage according to an output voltage outputted from the electric power converter, and utilizes a first threshold value to detect the control voltage. The power factor correction controller can control the power factor correction circuit to operate in different modes according to various levels of a load. Therefore, an objective according to the present invention for reducing electric power consumption of the electric power converter in a light load or a no-load mode and improving energy transmission efficiency can be attained.

Secure videoconferencing system and method thereof

Shearing device for side strip

Ratchet wrench structure

本發明係關於一種棘輪扳手結構，其係包括：一本體係設有第一容槽、第二容槽及第三容槽；一棘輪係樞設於第一容槽內；一制齒係容置於第二容槽內，該制齒後側係設有凹弧槽，該制齒係凸設有凸塊，該凸塊與凹弧槽間係有第一抵面，制齒遠離第三容槽開放端係設有第二抵面；一轉向組係樞設於第三容槽內，該轉向組係包括：一轉向件、一第一頂帽及一彈性元件，一轉向件係設有圓柱塊以樞設於第三容槽內，該圓柱塊係設有限制槽，該圓柱塊一端係設有頂面，該頂面係抵於第二抵面上，藉由第二抵面之限制，該轉向件係樞設於第三容槽處；一第一頂帽及彈性元件係容設於限制槽內，該第一頂帽外周面係靠抵於第一抵面上，藉由第一抵面限制第一頂帽，第一頂帽再限制轉向件，轉向件即樞設於第三容槽處。

Ecofriendly water-repellant colored fabric manufacturing device

Ratchet wrench structure

本發明係關於一種棘輪扳手結構，其係包括：一本體係設有頭部及第一齒部；一驅動頭係樞設於頭部內，該驅動頭係設有卡制部、平面、容置空間、套接部、容桿孔、容槽、第一邊面及第二邊面；一制齒係容置於容置空間內，制齒係設有第二齒部以與第一齒部相嚙合，制齒遠離第二齒部側係靠抵於卡制部之平面處，制齒係設有容置孔；一控制組係包括：轉動盤及作動彈簧；該轉動盤係蓋設於頭部頂面，該轉動盤係設有撥動栓、凹孔、槽孔，該轉動盤係凸塊，凸塊與撥動栓間係設有容室；該作動彈簧係座落於驅動頭上端面，該作動彈簧一端係設有延伸腳，延伸腳係容置於制齒之容置孔內，作動彈簧另端延伸形成卡制端，卡制端係套設於撥動栓上，該卡制端係設於容室處。

Modular fence

Cross-linked peptides and proteins, methods of making same, and uses thereof

Modular fence

A modular picket fence including a pair of vertical posts (12, 14) positioned at suitable distance. A pair of horizontal upper and lower rails (18, 22) extend between the vertical posts. The upper rail has a plurality of aperture (30), which are aligned with a plurality of aperture (30) on the lower rail. Vertical pickets (16) are inserted into the rail apertures. The end portion of each vertical picket has two transverse apertures (32, 34). A locking member (40) is assembled inside each end portion of the vertical picket. The locking member has spring biased stoppers (44) extending through the transverse apertures at the end portion of the vertical picket, and further extending inside the horizontal rail when the end portion of the vertical picket is inserted into one of the apertures of the horizontal rail, thereby preventing vertical movement of the vertical pickets with respect to the horizontal rails.

Photo-patternable dielectric materials and formulations and methods of use

Printed circuit board

A printed circuit board includes a first signal via, a second signal via, and a first ground via. A distance between the first ground via and the first signal via is substantially equal to a distance between the first ground via and the second signal via.

LED-based surface light-source device

Nitride transistor structure enhances the electron mobility and the carrier concentration of a two-dimensional electron gas channel to achieve efficacy of increasing performance

本發明係為一種氮化物電晶體結構及其製作方法，藉由在氮化物電晶體結構中插入一層或多層以較低五三比成長之氮化物中間層，進一步改善二維電子氣通道之電子遷移率與載子濃度，來達到提升氮化物電晶體性能之功效。

Method of manufacturing mesocarbon microbeads

本發明專利是一種介相碳微球之製作方法，提供一氣氛壓力於一瀝青溶液內並進行加熱攪拌處理，有效地縮短瀝青熱處理時間，增加瀝青中高分子量成分，促使瀝青溶液能夠快速生成大量的介相碳微球；且本發明係使用另一瀝青當作潤濕溶劑，與原本的瀝青溶液製作成待萃取流體，可有效地節省大量潤濕(有機)溶劑的使用，更可有效地回收再利用剩餘的瀝青溶液，與原本的瀝青溶液混合之後繼續使用，減少環境污染，而達到節省能源、增加產率以及降低生產成本之功效。

Improved structure of solid-state electrolytic capacitor

遠程觸控裝置

Fence accessory

The present invention is directed to fence accessory comprising at least two ornament bodies (1,3), each of the at least two ornament bodies comprising a first connecting part (5A) and a second connecting part (5B) at two opposing ends thereof, wherein the first connecting part of one of the at least two ornament bodies and the second connecting part of another one of the at least two ornament bodies are configured to be connected to a fence bar (2) and clamped together as one unit, and wherein the first connecting part and the second connecting part of each of the at least two ornament bodies are mirror image of each other.

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