СТЕНТ

Изобретение относится к медицинской технике, а именно к стенту, предназначенному для введения в полость тела человека или животного и размещения в ней. Стент имеет первую конфигурацию при введении, и указанный стент после введения в полость тела и размещения в ней предназначен иметь вторую конфигурацию. Стент содержит, по меньшей мере, одну сохраняющую часть, предназначенную для сохранения просвета в полости тела, и, по меньшей мере, одну расширяющуюся часть, предназначенную для удерживания стента в размещенном положении. В первой конфигурации, по меньшей мере, одна расширяющаяся часть имеет первый уменьшенный размер поперечного сечения, а во второй конфигурации, по меньшей мере, одна расширяющаяся часть имеет второй увеличенный размер поперечного сечения. По меньшей мере, одна сохраняющая часть во второй конфигурации имеет размер поперечного сечения, по меньшей мере, вдоль части продольной длины сохраняющей части, меньший нормального размера поперечного сечения полости тела вдоль продольной ...

СТЕНТ

... 1. Стент для введения в полость тела человека или животного и размещения в ней, причем указанный стент предназначен иметь первую конфигурацию при введении, и указанный стент после введения в полость тела и размещения в ней предназначен иметь вторую конфигурацию, ! отличающийся тем, что указанный стент содержит ! по меньшей мере, одну сохраняющую часть, предназначенную для сохранения просвета в полости тела, и ! по меньшей мере, одну расширяющуюся часть, предназначенную для удерживания стента в размещенном положении, ! причем в первой конфигурации указанная, по меньшей мере, одна расширяющаяся часть имеет первый уменьшенный размер поперечного сечения, а во второй конфигурации указанная, по меньшей мере, одна расширяющаяся часть имеет второй увеличенный размер поперечного сечения, и ! указанная, по меньшей мере, одна сохраняющая часть во второй конфигурации имеет размер поперечного сечения, по меньшей мере, вдоль части продольной длины сохраняющей части, меньший размера поперечного сечения ...

СИСТЕМЫ И СПОСОБЫ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЯ РАСШИРИТЕЛЬНОГО КОЛЬЦА

FROM SEVERAL COMPONENTS EXISTENCE ENDOLUMINALE TRANSPLANT ARRANGEMENT

ENDOLUMINALE DEVICE WITH SUPERELASTIC ONES AND PLASTIC DUCTILE ONE SECTIONS

SYSTEM FOR THE FILE OF A PROXIMALLY EXPAND STENTS

A STENT

MEDICAL DEVICES FROM NITINOL WITH OBTAINED VARIABLE STIFFNESS THROUGH W�RMEBEHANDLUNG

STENT WITH VARIABELEN CHARACTERISTICS

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Infundibular reducer devices

METHODS AND APPARATUS FOR INTRALUMINAL PLACEMENT OF A BIFURCATED INTRALUMINAL GRAFT

An aortic graft is provided with a unique combination of self-expanding and balloon expandable wires. The graft is bifurcated and includes ipsilateral and contralateral legs. Two extension grafts are provided for frictional engagement with the legs of the aortic graft. For placement, an introducer assembly including a dilator and a sheath assembly provides access for the introduction of a main catheter and a directional catheter. A balloon is provided on the main catheter for expanding the wires. The directional catheter, which includes a deflecting spring portion, permits placement of a guidewire through the ipsilateral leg and into the contralateral leg. In turn, a second introducer sheath and a second catheter assembly are provided contralaterally for introduction of a graft extension. Upon balloon-expansion, the graft extension is frictionally engaged with the contralateral leg of the aortic graft. A third catheter assembly including a second extension graft is provided for introduction ...

DIAMETRICALLY ADJUSTABLE ENDOPROSTHESES AND ASSOCIATED SYSTEMS AND METHODS

A diametrically adjustable endoprosthesis includes a controlled expansion element extending along at least a portion of a graft and is supported by a stent. The controlled expansion element diametrically constrains and limits expansion of the endoprosthesis. Upon deployment from a smaller, delivery configuration, the endoprosthesis can expand to the initial diameter set by the controlled expansion element. Thereafter, the endoprosthesis can be further diametrically expanded (e.g., using balloon dilation) by mechanically altering the controlled expansion element.

HEART CHAMBER PROSTHETIC VALVE IMPLANT WITH BASE, MESH AND DOME SECTIONS WITH SINGLE CHAMBER ANCHORING FOR PRESERVATION, SUPPLEMENTATION AND/OR REPLACEMENT OF NATIVE VALVE FUNCTION

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed.

TRANSCATHETER VALVE PROSTHESIS

A heart valve system, the system including a radially self-expandable tubular body and a valve. The tubular body having an inflow end and an outflow end, and the tubular body including a proximal-most end at the inflow end and a distal-most end at the outflow end. The tubular body including a plurality of arched beams at the outflow end of the tubular body such that the arched beams form the distal-most end of the tubular body. Connection points linking the inflow end of the tubular body and the arched beams, a number of connection points being equivalent to a number of the valve leaflets. Each arched beam being directly attached to an adjacent arched beam such that the arched beams are continuous along the entire circumference of the tubular body at the outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets.

COMBINED BALLOON-EXPANDING AND SELF-EXPANDING STENT

A stent comprises a plurality of segments including a first balloon expandable segment which is not self-expanding, a second balloon expandable segment which is not self-expanding and a first self-expanding segment. The first self- expanding segment is disposed between the first and second balloon expandable segments. The segments are axially displaced from one another.

FLEXIBLE AND EXPANDABLE STENT

A stent consisting of at least two parts in juxtaposition, one part being o f self-expandable characteristics while the other part is balloon expandable.< /SDOAB> ...

ACTIVELY CONTROLLABLE HEART VALVE IMPLANT AND METHODS OF CONTROLLING SAME

A mitral valve implant includes a force-expanding mitral valve lattice having an interior orifice and a self-expanding valve trampoline attached at the interior orifice of the force-expanding mitral valve lattice. The mitral valve lattice is self-expandable to a first configuration and force expandable from the first configuration to a second configuration. The configurations can be circular or D-shaped. The mitral valve lattice comprises jack screws adjusting configurations of the mitral valve lattice. The valve trampoline has a cylindrical central region comprising valve leaflets. An outwardly flaring implant skirt is attached to the mitral valve lattice exterior. Wall-retaining wires are attached to the mitral valve lattice, are petal-shaped, and have a pre-set, radially outward, memory shape. The wires and skirt impart a force on a respective side of the native mitral valve when the mitral valve lattice is expanded within an annulus of the native mitral valve.

ENDOPROSTHESIS

An endoprosthesis is disclosed. The endoprosthesis can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The endoprosthesis comprises a first end portion expandable to a first diameter, a second portion expandable to a second diameter and an intermediate portion expandable to a third diameter that is less than at least one of the first diameter and second diameter. The endoprosthesis can define different shapes such as dog-bone, hourglass or a tapered shape. The intermediate portion is diametrically adjustable to a larger diameter upon application of an expansion force to the midsection and can remain at the larger diameter and maintain the deployed diameter in the absence of the expansion force.

A FLOW REGULATING DEVICE IN THE HEART

A blood flow regulator (100) for creating a shunt in the heart, comprising; a proximal element (101) having a general disc-shape, defined by a braid of one or more wires extending about a central aperture (103) of the proximal element; a distal element (102) having a general disc-shape, defined by a braid of one or more wires extending about a central aperture (104) of the distal element; and a third element (105) defining a neck section intermediate the proximal and distal elements and forming a cavity (106) having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop (107) of a wire extending radially outwardly from a center (108) of the distal element and returning towards said center of said distal element.

LATTICE

The invention relates to medical devices and methods of using them. The devices are prostheses which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The prostheses are configured to have a lattice resistant to dilation and creep, which is defined by a plurality of openings. The prosthesis may also optionally have a stent disposed proximal to the lattice. In exemplary embodiments, the fluoropolymer is expanded polytetrafluoroethylene. The composite materials exhibit high elongation while substantially retaining the strength properties of the fluoropolymer membrane. In at least one embodiment, the lattice is made of a composite material that includes a least one fluoropolymer membrane including serpentine fibrils and an elastomer. A lattice including a generally tubular member formed of a composite material including a least one fluoropolymer membrane containing serpentine fibrils and an elastomer is also ...

HEART VALVE REPLACEMENT CATHETER

The disclosure pertains to catheter-based delivery system for intravascular heart valve replacement and methods of use thereof. In addition to the replacement heart valve and associated positioning and installation components, the delivery catheter of the system includes a deployable filter element, an actuator for the deployable filter element, and a fluid expandable balloon located proximate the distal end of the delivery catheter. The delivery catheter may be capable of carrying out a valvuloplasty and/or a determination of a distance within a patient.

STENT SYSTEM FOR PREVENTING RESTENOSIS

A system for treating a body lumen is disclosed. The system comprises an outer stent and an inner stent disposed within the lumen of the outer stent. At least one end of the inner stent extends outside of the lumen of the outer stent, so that the end of the inner stent contacts and conforms to the body lumen wall that is adjacent the end of the outer stent. A coating can be disposed on a surface, preferably the outer surface, of the inner stent. The coating contains a therapeutic substance that may be released into the body lumen wall to help in preventing restenosis. Also disclosed is a stent having a balloon-expandable portion connected to a self-expanding portion. Methods for deploying the system and the stent are also disclosed.

Expandable coil stent

An implantable coil stent comprises at least a first curved segment and a second curved segment which arc about the longitudinal axis of the stent. An expandable link extends between the second end of the first curved segment and the first end of the second curved segment.

CARDIAC VALVE ANNULUS RESTRAINING DEVICE

A catheter based system for treating mitral valve regurgitation includes a reshaping device having a body and a plurality of movable anchoring barbs attached to the body of the device. The reshaping device can be made from a biocompatible material having suitable shape memory properties. The devices of the current invention can be self expandable, balloon expandable, or a combination self expandable and balloon expandable. One embodiment of the invention includes a method for attaching a reshaping device to the annulus of a mitral valve, moving the body of the device from a fully expanded configuration to a resting configuration, and thereby reshaping the mitral valve annulus.

DEVICES AND METHODS FOR TREATMENT OF ABDOMINAL AORTIC ANEURYSM

Devices and methods for treating aneurysms, such as abdominal aortic aneurysms (“AAA”) generally include one or more stent-graft devices. Some embodiments include self-expanding and/or balloon-expandable stent components and one or more graft components coupled with the stent components. Using various combinations of self-expanding stent members, balloon-expandable stent members, graft members, and/or anchoring members enhances the anchoring abilities of a stent-graft device to prevent leakage around it, and may further allow the device to be adjusted after placement at a site for treatment. Some embodiments further include a skirt graft member for further prevention of leakage and/or device slippage.

Catheter with integrated embolic protection device

A prosthetic heart valve delivery catheter includes an embolic filter to provide integrated embolic protection to inhibit the release of emboli into the aorta, the aortic arch or branch vessels, and other vasculature during transvascular heart valve replacement procedures. The embolic filter will usually be fixedly or movably attached to a shaft of the delivery catheter proximal of the prosthetic heart valve.

PROSTHESIS AND METHOD FOR REPLACING THE NUCLEUS PULPOSUS OF AN INTERVERTEBRAL DISC OR FOR REPLACING AN ENTIRE INTERVERTEBRAL DISC

A prosthetic nucleus pulposus (5) for replacing the natural nucleus pulposus of an intervertebral disc. The prosthetic nucleus pulposus comprises a partially collapsed sealed envelope formed from a material which is permeable to extracellular body fluid. The envelope contains a solute (20) which provides an osmotic potential across the walls of the envelope. In use, the partially collapsed envelope is surgically implanted in the hallowed-out interior of an intervertebral disc and is allowed to absorb fluid, whereby expansion of the envelope and subsequent disc expansion is accomplished.

Endoluminales Transplantat

Branch stent

MIX STENT

ENDOLUMINALE PROSTHESIS

FLEXIBLE STENT AND MANUFACTURING PROCESS FOR IT

DEVICE TO IN-SITU-EMBOLIESCHUTZ

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Delivery system and method for self-centering a proximal end of a stent graft

A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.

Low profile medical device

Implant

The invention relates to an implant (1) for use in the occlusion of aneurysms (A) in blood vessels (Z) in the region of vascular ramifications (X, Y), in particular bifurcation aneurysms, wherein the implant (1) is present in an expanded state in which the implant is implanted in the blood vessel (Z) and in a contracted state in which the implant is movable through the blood vessel (Z). The implant (1) has a proximal fixing section (3), by which the implant (1) can be fixed to a vessel wall of the blood vessel (Z), a distal section (5), in which the implant (1) is radially expanded in relation to the fixing section (3) and which is intended for positioning in or before the aneurysm (A), and a transition section (4) between the fixing section (3) and the distal section (5). The implant (1) is made up of filaments (10) which are connected to one another or intersect, and in the transition section (4) one or more filaments (10) coming from the fixing section (3) or distal section (5) come ...

HYBRID STENT

A stent (10) comprises a plurality of segments, including at least one segment (100) which is in the form of a coil and at least one segment (90) which is in a form other than a coil and which is balloon expandable or self-expandable.

SYSTEM AND METHOD FOR DEPLOYING A PROXIMALLY-FLARING STENT

Disclosed herein are proximally-flaring stents and balloon catheter systems and methods for using the same to restore patency to a side branch and its ostium at a vessel bifurcation, where the side branch can only be approached from the direction of the main artery. The system and methods include a proximally-flaring stent (10) and one or more balloon catheters (250, 400) with inflatable balloons that are able to push a flanged proximal portion (40) of the proximally-flaring stent entirely against the artery walls of the main artery of the side branch so that blood flow is not occluded.

SYSTEMS AND METHODS OF MANUFACTURING AND USING AN EXPANSION RING

A method of connecting an expansion ring to at least one end of a braided implant is disclosed. The method can include positioning the braided implant about a tube; everting an end portion of the braided implant over a first end of the tube; assembling an expansion ring to the braided implant, the expansion ring being a multi-leaved expansion ring including clips terminating with an open-ended coupling opening. The openings can be pushed over a set of intersecting wires of the braided implant at respective circumferential locations on or adjacent the first end of the tube. The method can also include closing the openings over the set of intersecting wire; trimming ends of the braided implant; and reversing eversion of the braided implant thereby positioning the expansion ring internal to the braided implant.

TRANSCATHETER VALVE PROSTHESIS

A heart valve system, the system including a radially self-expandable tubular body, a valve, and a tubular fabric. The tubular body having an inflow end and an outflow end. The valve being coupled to the tubular body and including a plurality of valve leaflets. The fabric being disposed on an outer surface of the tubular body, and the fabric having an inflow end and an outflow end. Furthermore, the outflow end of the fabric being directly connected to an outer circumferential edge of the valve.

INTEGRATED HYBRID HEART VALVES

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate a valve-in-valve (ViV) procedure. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates a ViV procedure.

PROSTHETIC VALVE AND DELIVERY TOOL THEREFOR

An apparatus for use at a native valve of a heart of a subject comprises a tubular frame (30) circumscribing a longitudinal axis to define a lumen, a valve member (62) disposed within the lumen and coupled to the tubular frame, an outer frame (40), and a pin (50). The outer frame is composed of a shape-memory alloy. The tubular frame and the pin are composed of a material that is not the shape-memory alloy. The outer frame comprises a flange (42), defines an eyelet (44), and is disposed radially outward from the tubular frame. The pin defines a shaft (52) and a head (54), and couples the outer frame to the tubular frame. The head is disposed against the outer frame, radially outward from the eyelet, the shaft extends from the head through the eyelet to the tubular frame, and the shaft is welded to the tubular frame.

PROSTHESIS AND METHOD FOR REPLACING THE NUCLEUS PULPOSUS OF AN INTERVERTEBRAL DISC OR FOR REPLACING AN ENTIRE INTERVERTEBRAL DISC

A prosthetic nucleus pulposus (5) for replacing the natural nucleus pulposus of an intervertebral disc. The prosthetic nucleus pulposus comprises a partially collapsed sealed envelope formed from a material which is permeable to extracellular body fluid. The envelope contains a solute (20) which provides an osmotic potential across the walls of the envelope. In use, the partially collapsed envelope is surgically implanted in the hallowed-out interior of an intervertebral disc and is allowed to absorb fluid, whereby expansion of the envelope and subsequent disc expansion is accomplished.

URINARY INCONTINENCE PROTECTOR WHICH IS SIZE-ADJUSTABLE

A urinary incontinence protector which is size-adjustable, according to an embodiment of the present invention, comprises the following: a urinary incontinence protector body having a hole on one side to communicate with the inside; wing members provided on upper and lower portions of the urinary incontinence protector body; and connection members with one ends connected to each wing member located on the upper and lower portions of the urinary incontinence protector body, and the other ends inserted into the urinary incontinence protector body through the hole. COPYRIGHT KIPO 2017 ...

A HYBRID INTRALUMINAL DEVICE WITH VARYING EXPANSION FORCE

A hybrid intraluminal device and a method for fabricating the device is described. The device has structural elements which have different properties. One portion of the device may contain a stent having a zigzag configuration. A second portion of the device may contain a stent having a braided configuration. The first and second portions may possess the same architectural pattern but yet exhibit variation in radial force as a result of various properties of the structural elements. The portions are attached to a coating to form a hybrid stent. Gaps between the different stent sections provide flexibility to the stent. The first and second portions may be configured in numerous ways. The structural features of the hybrid stent can be adapted to satisfy the criteria of specific medical applications.

METHOD OF MANUFACTURING A POLYMERIC STENT WITH A HYBRID SUPPORT STRUCTURE

Methods of manufacturing polymeric intraluminal stents and intraluminal stents are disclosed. The methods provide a method of manufacturing polymeric intraluminal stents (10) having a structure with hybrid strut configuration containing at least one circumferential ring element (40) in the structure in combination with geometric strut columns (20).

BIFURCATED ANEURYSM TREATMENT ARRANGEMENT

A vascular aneurysm-treating stent arrangement (10) having a proximal end (22) and a distal end (24), the stent being formed of a differentially expandable material, wherein the distal end (24) is deformably expandable to a cone shape (50) . A deformable enclosed chamber (50) is arranged on the distal end (24) of the stent (20) and nests within the aneurysm (62) . A different embolic agent is introduced into the aneurysm and into the chamber.

Device to treat vascular defect and method of making the same

The device includes a braided component formed from a network of wires having at least two different diameters. The outer surface of the braided component has roughness from about 30 microns to about 90 microns and the wires of different diameters provide the desired porosity to the device. The network of wires includes a biocompatible shape memory alloy and a noble metal as a coating material.

METHOD FOR AORTIC REPAIR AND AORTIC REPLACEMENT

An endovascularly deployed prosthetic includes a portion for being positioned within an ascending aorta. The prosthesis includes a replacement aortic valve on a proximal end thereof. The prosthesis includes an increased diameter portion that seals against the aorta at a more distal portion, and a pair of conduits extend from the increased diameter portion to the coronaries for fluidly coupling the coronaries to the prosthesis.

Pulmonary airflow

Devices, systems, and methods for improving airflow within an airway. One example embodiment includes a method for treating a subject. The method includes (1) placing an expandable object into one or more airways of the bronchial tree of the subject, (2) expanding the expandable object within at least one of the one or more airways such that at least a portion of a wall of the one or more airways is expanded, and (3) placing a stent in the airway such that a portion of the stent is adjacent to the portion of the wall of the one or more expanded airways.

CURVILINEAR CERVICAL INTERBODY DEVICE

An interbody spacer assembly includes a pair of end pieces spaced apart by a connector extending between them. The end pieces extend generally parallel to the end plates of adjoining vertebral bodies. Fasteners connect the end pieces to the vertebral bodies. Bone graft material or solid bone can be placed in the interior space defined by the end pieces and connector, which bone graft material or solid bone eventually fuses together and to the adjoining end plates through the end pieces. The spacer assembly has ratchets to connect the two end pieces. The ratchets near the fasteners are more closely spaced than the ratchets further from the fasteners, allowing the spacer assembly to more closely approximate the lordosis of the spine.

Delivery system and method for self-centering a Proximal end of a stent graft

A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen.

Blutgefässtransplantat

System zur Herstellung eines abzweigenden Transplantats

MISCH-STENT

Delivery system for implantable medical device

EXPAND-CASH STENT WITH A SELFEXPAND-CASH SECTION

EXPAND OSTIUMENDOPROTHESE AND SUPPLY SYSTEM

IMPLANTIERBARE CONTAINER SUPPORT

HYBRID STENTVORRICHTUNG

EXPAND-CASH SPULENFÖRMIGER STENT

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Modular vascular prosthesis and methods of use

The present invention relates a vascular prosthesis and related assembly methods that includes a plurality of modular segments inter-engaged by flexible, and preferably lockable, inter-engageable elements forming joints or other connector areas. The segments may have a number of different mechanical properties and may be assembled by the clinician, through mechanical or chemical joining, to customize the prosthesis for a specific patient or application.

Proximally Self-Locking Long Bone Prosthesis

A femoral stem hip implant for insertion into a surgically created aperture in a femur includes a monolithic femoral stem made of shape memory material. The stem is configured to be inserted into the aperture, has a proximal portion and a longitudinal axis. The shape memory material within the proximal portion has a cross-section perpendicular to the longitudinal axis. At least a portion of the shape memory material within the proximal portion is in a compressed state by application of a plurality of compressive forces at a temperature below an austenitic finish temperature of the shape memory material so that the cross-section expands through shape memory effect via the formation of austenite in response to a temperature increase after insertion into the aperture thereby causing a locking-force to be exerted against an inner surface of the aperture, the locking force being sufficient to stabilize the implant in the aperture.

Branch vessel prostheses

The present embodiments provide a branch vessel prosthesis for placement at least partially between a main vessel and a branch vessel of a patient. The branch vessel prosthesis has a graft including a generally tubular body of a biocompatible material. At least one stent is coupled to a proximal region of the graft, and at least one stent is coupled to a distal region of the graft. The proximal region of the graft includes a generally straight configuration in an expanded deployed state that is substantially parallel to a longitudinal axis of a main vessel. The distal region of the graft includes a generally straight configuration in the expanded deployed state that is substantially parallel to a branch vessel. A curvature of a central region varies an angle in which the distal region of the graft is disposed relative to the proximal region.

Device for endovascular aortic repair and method of using the same

A device and method for endovascular repair of a patient's aorta is disclosed. The device includes a frame component that has a balloon-expandable frame and a self-expanding frame secured to the balloon-expandable frame. The device also includes a valve element positioned at the proximal end of the frame component. The device may include another prosthetic component that may be secured to the frame component. The prosthetic component may include at least one conduit configured to receive a covered stent.

Collapsible valve prosthesis

A collapsible valve prosthesis includes an armature and a set of prosthetic valve leaflets supported by the armature. The armature is expandable from a contracted condition to an expanded condition for anchoring at an annulus of a natural valve site, and includes a tubular intra-annular portion defining a blood flow lumen having an inflow side and an outflow side. The tubular intra-annular portion supports the prosthetic valve leaflets in the blood flow lumen and is provided with outward formations for coupling with the natural valve site. The armature includes an over-annular portion linked to the intra-annular portion to extend collar-like over the annulus of the natural valve site at the inflow side of the blood flow lumen. The armature may also include an under-annular portion to extend collar-like at the outflow side of the blood flow lumen. The prosthesis may permit mitral valve replacement (MVR) without removing the native valve leaflets and the chordae tendineae.

Integrated hybrid heart valves

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate a valve-in-valve (ViV) procedure. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates a ViV procedure.

AORTIC VALVE STENT GRAFT

An implantable endoluminal prosthesis for replacing a damaged aortic valve is provided. In one embodiment, the prosthesis includes a balloon-expandable stent, a tubular conduit that extends into the ascending aorta, and a self-expanding stent. The tubular conduit extends across the balloon-expandable stent. The tubular conduit includes an artificial valve. The self-expanding stent extends across the tubular conduit into the ascending aorta. The balloon-expandable stent, the tubular conduit, and the self-expanding stent are coupled to provide unidirectional flow of fluid into the aorta and further into the coronary arteries. Also provided is a method for implanting the endoluminal prosthesis. 140-. (canceled)41. An endoluminal prosthesis comprising:at least one stent; anda tubular conduit comprising an aortic valve replacement that allows fluid to pass in an upstream to downstream direction, wherein at least a portion of the tubular conduit overlaps at least a portion of the at least one stent,wherein an outflow end of the tubular conduit terminates at a location between an upstream proximal end and a downstream distal end of the at least one stent,wherein the at least one stent comprises a proximal zone having a first diameter and a distal zone having a second diameter, where the proximal zone is upstream of the distal zone, where the first diameter is narrower than the second diameter, and there is a taper between the first and second diameters, andwherein a proximal end of the aortic valve replacement is disposed distal to a distal end of the proximal zone.42. The endoluminal prosthesis of claim 41 , wherein the taper of the at least one stent is positioned at least partially downstream of the aortic valve replacement.43. The endoluminal prosthesis of claim 41 , wherein the at least one stent comprises at least one uncovered region to allow fluid to pass radially outside of an outer perimeter of the at least one stent after passing through the aortic valve ...

STENTS, SYSTEMS, AND METHODS FOR GASTROINTESTINAL TRACT TREATMENT

The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section. 1. A stent , comprising: a flared section;', 'a medial section extending from the flared section, wherein a diameter of the flared section is greater than a diameter of the medial section; and, 'a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends, the tubular scaffold comprisinga liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.2. The stent of claim 1 , wherein the liner is spaced apart from a medial anchoring region of the medial section to promote tissue ingrowth with the medial section.3. The stent of claim 2 , wherein the medial anchoring region is provided at an expanded portion of the medial section claim 2 , and wherein the expanded portion has a third diameter greater than the diameter of the medial section.4. The stent of claim 3 , wherein the liner is spaced from the expanded portion to promote tissue ingrowth with the expanded portion.5. The stent of claim 1 , wherein the anchoring region is located along a sloped portion of the flared section claim 1 , and wherein the sloped portion extends away from a central longitudinal axis extending through the lumen.6. ...

Stent Delivery System Having Dynamic Deployment and Methods of Manufacturing Same

A stent delivery system for dynamic deployment of a stent loaded thereon and a method of manufacturing the system. The stent delivery system includes a balloon catheter with a balloon in a spirally twisted delivery configuration on which a stent is crimped or otherwise loaded. The stent is made from a single, continuous strand of wire formed into a sinusoidal waveform that is wrapped into a helical pattern and joined at selected crowns. Upon inflation of the spirally twisted balloon of the stent delivery system, the stent undergoes dynamic deployment such that the stent in a deployed or expanded configuration has crowns with obtuse deployment angles and crowns with acute deployment angles. 1. A method of manufacturing a stent delivery system for dynamic deployment of a stent comprising:twisting an uninflated balloon of a stent delivery catheter into a spirally twisted delivery configuration; andloading a stent onto the spirally twisted balloon, the stent being made from a single, continuous strand of wire formed into a sinusoidal waveform that is wrapped into a helical pattern and joined at selected crowns, wherein upon inflation of the spirally twisted balloon the stent undergoes dynamic deployment such that the stent in a deployed configuration has crowns with obtuse deployment angles and crowns with acute deployment angles.2. The method of claim 1 , wherein the obtuse deployment angles are in the range of greater than 90 ninety degrees to less than or equal to 180 degrees and the acute deployment angles are in the range of greater than or equal to 70 degrees to less than 90 degrees.3. The method of claim 1 , wherein in the deployed configuration one or more segments of the stent having crowns with obtuse deployment angles possess a higher hoop strength than one or more segments of the stent having crowns with acute deployment angles.4. The method of claim 1 , wherein the spirally twisted balloon is configured to untwist upon inflation and thereby apply a twisting ...

Prosthetic valve support structure

The present invention is directed to prostheses including a support structure having a proximal end and a distal end, and a motion limiting member attached to the distal end of the support structure, wherein the motion limiting member is configured to restrict radial expansion of the distal end of the support structure. Methods for delivering the prosthesis are also provided.

DEVICES AND METHODS FOR TREATMENT OF THE EUSTACHIAN TUBE AND SINUS CAVITY

A polymeric stent can be implanted for treatment of the Eustachian tube. The stent can be designed to have length-dependent radial strength to allow it to stay within the Eustachian tube and to allow normal closing and opening of the Eustachian tube. A balloon can be used to implant the stent, and the balloon can be coated with a therapeutic agent. A coated balloon can also be used to transfer therapeutic agents to the sinus cavity during a balloon sinus dilation procedure. 110-. (canceled)11. A system for delivering a stent in the Eustachian tube , the system comprising:a catheter including a body and a balloon at an end of the body, the balloon configured to carry a stent for delivery through a nasopharynx cavity and into a Eustachian tube of a patient.12. The system of claim 11 , further comprising a stent mounted onto the balloon.13. The system of claim 11 , further comprising a guidewire having an end segment sized for insertion into the Eustachian tube and a plurality of wire marks applied or etched on an exposed surface of the end segment claim 11 , and the catheter includes a passageway configured to receive the guidewire.14. The system of claim 13 , wherein each of the wire marks has a characteristic which distinguishes the wire mark from an adjacent wire mark claim 13 , and the characteristic is a color claim 13 , a shade claim 13 , a shape claim 13 , an alphanumeric character claim 13 , or a combination thereof.15. The system of claim 13 , wherein each of the wire marks is a band that encircles the end segment of the guidewire claim 13 , and each band has an axial size that is at least 2 mm.16. The system of any one of claims 13 , wherein the end segment of the guidewire is configured to emit light.17. The system of any one of claims 13 , wherein the end segment of the guidewire includes a stabilization feature configured to expand and engage a surface of the Eustachian tube.18. (canceled)19. (canceled)20. The system of any one of claims 11 , wherein the ...

RESILIENT ARTHROPLASTY DEVICE

The disclosure is directed to a resilient implant for implantation into human or animal joints to act as a cushion allowing for renewed joint motion. The implant endures variable joint forces and cyclic loads while reducing pain and improving function after injury or disease to repair, reconstruct, and regenerate joint integrity. The implant is deployed in a prepared debrided joint space, secured to at least one of the joint bones and expanded in the space, molding to surrounding structures with sufficient stability to avoid extrusion or dislocation. The implant has opposing walls that move in varied directions, and an inner space filled with suitable filler to accommodate motions which mimic or approximate normal joint motion. The implant pads the damaged joint surfaces, restores cushioning immediately and may be employed to restore cartilage to normal by delivering regenerative cells. 1. A method of treating a patient's joint comprising:a. providing a resilient orthopedic implant with a first wall, a second wall and a side wall wherein the first wall is configured to engage a first bone, the second wall is configured to conform around a portion of a second bone, the side wall is configured to extend between the first wall and the second wall, and the implant further comprises an interior portion configured to be directly enclosed by the first wall, the side wall, and a portion of the second bone;b. deploying the implant, within the joint to be treated, between the first bone and the second bone; andc. securing at least one of the first or second walls to one of the bone members of the joint;wherein the deployed implant treats a joint in a patient in need thereof.2. The method of claim 1 , wherein the first bone is an articulating end of an acetabulum of a pelvic bone and the second bone is a femoral head.3. The method of claim 1 , wherein the second bone is a humeral head in a shoulder claim 1 , a condyle of a knee claim 1 , or a head of a humerus in the elbow.4. ...

DEVICE FOR ENDOVASCULAR AORTIC REPAIR AND METHOD OF USING THE SAME

An intraluminal vascular prosthesis assembly, having a hollow cylindrical body with a first end and a second end is provided. The assembly includes, at its first end, a first vascular prosthesis portion, and at its second end, a second vascular prosthesis portion which has only a prosthesis material. The vascular prosthesis assembly has a stent portion which is provided between the first vascular prosthesis portion and the second vascular prosthesis portion, the stent portion being free of prosthesis material to allow fluid flow therethrough and received within the aortic arch and spanning the brachiocephalic artery, left common carotid artery, and left subclavian artery when placed within the aortic arch of a patient. 1. An intraluminal vascular prosthesis assembly, having a hollow cylindrical body with a first end and a second end. This application is a continuation of U.S. patent application Ser. No. 16/042,286 entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which was filed on Jul. 23, 2018, which is a continuation of U.S. patent application Ser. No. 14/614,628 entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which was filed on Feb. 5, 2015, which is a continuation of U.S. patent application Ser. No. 14/569,306 entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which was filed on Dec. 12, 2014, which is a divisional of U.S. patent application Ser. No. 13/706,896, entitled “Device for Endovascular Aortic Repair and Method of Using the Same,” which claims the benefit under 35 U.S.C. § 119 to U.S. Provisional Application Ser. No. 61/567,458 entitled “Transcathetar Aortic Valve for Endovascular Aortic Repair,” which was filed on Dec. 6, 2011. Application Ser. No. 13/706,896 also claims priority under § 119 to U.S. Provisional Application Ser. No. 61/723,446 entitled “Transcathetar Aortic Valve for Endovascular Aortic Repair,” which was filed on Nov. 7, 2012. Each of the ...

RESILIENT ARTHROPLASTY DEVICE

The disclosure is directed to a resilient implant for implantation into human or animal joints to act as a cushion allowing for renewed joint motion. The implant endures variable joint forces and cyclic loads while reducing pain and improving function after injury or disease to repair, reconstruct, and regenerate joint integrity. The implant is deployed in a prepared debrided joint space, secured to at least one of the joint bones and expanded in the space, molding to surrounding structures with sufficient stability to avoid extrusion or dislocation. The implant has opposing walls that move in varied directions, and an inner space filled with suitable filler to accommodate motions which mimic or approximate normal joint motion. The implant pads the damaged joint surfaces, restores cushioning immediately and may be employed to restore cartilage to normal by delivering regenerative cells. 1. A resilient implant for the foot or ankle comprising:a first wall,a second wall,a side wall extending between the first wall and the second wall,a plurality of chords or anchors for securing the implant to at least one bone or one ligament.2. The resilient implant of claim 1 , wherein the implant comprises a mesh material.3. The resilient implant of claim 1 , wherein the first wall claim 1 , the second wall and the side wall define an interior portion.4. The resilient implant of claim 3 , wherein the interior portion is inflated with a resilient material.5. The resilient implant of claim 3 , wherein the interior portion is inflated with gas claim 3 , liquid claim 3 , gel claim 3 , slurry claim 3 , curable polymer claim 3 , foam claim 3 , sponge or combinations thereof.6. The resilient implant of claim 4 , wherein the resilient material in the interior portion maintains spacing between the first wall claim 4 , the second wall and the side wall.7. The resilient implant of claim 4 , wherein the resilient material in the interior portion provides support between the first wall claim 4 ...

PERCUTANEOUS HEART VALVE DELIVERY AND IMPLANTATION SYSTEM ENABLING FRACTURE OF A PREVIOUSLY PRESENT VALVE

A percutaneous heart valve delivery system including a valve delivery catheter coupled with a first inflatable balloon positioned at a distal end of the valve delivery catheter, wherein the first inflatable balloon is configured to fracture a previously implanted prosthetic heart valve; and a replacement transcatheter heart valve positioned proximal to the first inflatable balloon, wherein the replacement transcatheter heart valve is configured to be implanted subsequently within the previously implanted, fractured prosthetic heart valve, following fracture of the previously implanted heart valve without withdrawal of the percutaneous heart valve delivery system. Also disclosed are methods of implantation of a new heart valve within a previously implanted prosthetic heart valve and methods of valvuloplasty of a native heart valve. 1. A percutaneous heart valve delivery system comprising a valve delivery catheter coupled with:a first inflatable balloon positioned at a distal end of the valve delivery catheter, wherein the first inflatable balloon is configured to fracture a previously implanted prosthetic heart valve; anda replacement transcatheter heart valve positioned proximal to the first inflatable balloon, wherein the replacement transcatheter heart valve is configured to be implanted subsequently within the previously implanted, fractured prosthetic heart valve, following fracture of the previously implanted heart valve without withdrawal of the percutaneous heart valve delivery system.2. The percutaneous heart valve delivery system according to claim 1 , further comprising a handle coupled to the valve delivery catheter claim 1 , wherein the handle comprises an adjustment control connected to the first inflatable balloon claim 1 , wherein the adjustment control is configured to vary a position of the first inflatable balloon in the valve delivery catheter claim 1 , wherein the first inflatable balloon can be positioned distal claim 1 , at the same position or ...

HEART CHAMBER PROSTHETIC VALVE IMPLANT WITH BASE, MESH AND DOME SECTIONS WITH SINGLE CHAMBER ANCHORING FOR PRESERVATION, SUPPLEMENTATION AND/OR REPLACEMENT OF NATIVE VALVE FUNCTION

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed. 1. A device for expanded implantation within a heart chamber that is in fluid communication with an annulus comprising an annular plane and with a native valve having leaflets , the device comprising:a base section comprising a lower surface that is at least partially disposed on the annular plane, the lower surface at least partially disposed on the annular plane;an atrial dome section in pressured and frictional engagement with the chamber roof when the device is expanded and implanted;an intermediate section comprising a flexible and expandable mesh and operatively attached to the base section and the atrial dome section in operable connection with the base frame and top section; anda central cylinder valve support comprising a lower surface, the central cylinder valve support operatively attached to base section and comprising at least one prosthetic valve leaflet operatively attached therein, wherein the lower surface is located on or above the annular plane.2. The device of claim 1 , further comprising the at least one ...

HEART CHAMBER PROSTHETIC VALVE IMPLANT WITH BASE, SPRING AND DOME SECTIONS WITH SINGLE CHAMBER ANCHORING FOR PRESERVATION, SUPPLEMENTATION AND/OR REPLACEMENT OF NATIVE VALVE FUNCTION

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed. 1. A device for expanded implantation within a heart chamber that is in fluid communication with an annulus comprising an annular plane and with a native valve having leaflets , the device comprising:a base section comprising a lower surface that is at least partially disposed on the annular plane, the lower surface at least partially disposed on the annular plane;an atrial dome in pressured and frictional engagement with the chamber roof when the device is expanded and implanted;an intermediate section comprising a spring-like section and operatively attached to the base section and the atrial dome in operable connection with the base frame and top section, wherein the intermediate section comprising a spring-like section is adapted to achieve non-elastic compression and generate a resultant biasing force;a central cylinder valve support comprising a lower surface, the central cylinder valve support operatively attached to base section and comprising at least one prosthetic valve leaflet operatively attached therein, wherein ...

METHOD AND APPARATUS FOR CREATING A MODIFIED TISSUE GRAFT

A method and apparatus is provided for creating a modified tissue graft, wherein an anatomical site at which the modified tissue graft is to be placed is identified, desired characteristics for the modified tissue graft are identified based at least upon the anatomical site, one or more types of graft modifications and regions of the tissue graft to be modified are identified to achieve the desired characteristics; and at least a first area and a second area of the exterior surface of the tissue graft are modified by compressing, cutting and/or removing one or more portions thereof to create first designed surface features which cause the tissue graft to have first characteristics in the first area and second designed surface features which cause the tissue graft to have second characteristics in the second area. 1. A method of creating a modified tissue graft for connection at an anatomical site of a human body , comprising the steps of:(a) obtaining a tissue graft from a location different than said anatomical site, said tissue graft having an exterior surface;(b) identifying said anatomical site at which said modified tissue graft is to be placed;(c) identifying desired characteristics for said modified tissue graft, based at least upon the anatomical site;(d) identify one or more types of graft modifications and regions of said tissue graft to be modified, to achieve the desired characteristics; and(e) target resurfacing said tissue graft by using at least one template to modify at least a first area of said exterior surface of said tissue graft by compressing, cutting and/or removing one or more portions of said exterior surface of said tissue graft to create one or more first designed surface features which cause said modified tissue graft to have first characteristics in said first area and to modify at least a second area of said exterior surface of said tissue graft by compressing, cutting and/or removing one or more portions of said exterior surface of ...

HYBRID HEART VALVES

A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate valve-in-valve (ViV) procedures. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates ViV procedures. 1. A hybrid prosthetic heart valve having an inflow end and an outflow end , comprising:a valve member including a fabric-covered undulating wireform with alternating cusps and commissures supporting a plurality of flexible leaflets configured to regulate one-way blood flow therethrough, the valve member having no annular structural support; anda fabric-covered expandable inflow stent frame having a radially-expandable inflow end and an outflow end that undulates with peaks and valleys corresponding to an inflow end of the wireform, the stent frame being attached to and projecting in an inflow direction from an inflow end of the wireform; anda plurality of separate commissure posts connected to the outflow end of the stent frame and projecting axially therefrom so as to be located radially outward from the wireform commissures, wherein the flexible leaflets pass radially outward through the wireform commissures and attach to the commissure posts.2. The prosthetic heart valve of claim 1 , and wherein the ...

Stent with elastomeric elements

Disclosed is a self-expanding medical implant for placement within a lumen of a patient. The implant comprises a woven or non-woven structure having a substantially tubular configuration, and is designed to be low-profile such that it is deliverable with a small diameter catheter. The implant has a high recoverability and desirable mechanical properties.

LATTICE

The invention relates to medical devices and methods of using them. The devices are prostheses which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The prostheses are configured to have a lattice resistant to dilation and creep, which is defined by a plurality of openings. The prosthesis may also optionally have a stent disposed proximal to the lattice. In exemplary embodiments, the fluoropolymer is expanded polytetrafluoroethylene. The composite materials exhibit high elongation while substantially retaining the strength properties of the fluoropolymer membrane. In at least one embodiment, the lattice is made of a composite material that includes a least one fluoropolymer membrane including serpentine fibrils and an elastomer. A lattice including a generally tubular member formed of a composite material including a least one fluoropolymer membrane containing serpentine fibrils and an elastomer is also provided. 120.-. (canceled)21. An endoprosthesis comprising:a first stent;a second stent;a lattice interposed between the first stent and the second stent and including segments of varying lengths, the lattice being configured to expand to a first diameter to deploy within a vessel and expand in a sloped or stepped manner to a second diameter to accept and constrain a primary prosthesis within the lattice.22. The endoprosthesis of claim 21 , wherein the lattice includes an open structure configured to illicit a host biological response and interaction with an abluminal surface of the primary prosthesis.23. The endoprosthesis of claim 22 , wherein the abluminal surface of the primary prosthesis is coated with a drug or has an engineered microstructure to accelerate cellular ingrowth.24. The endoprosthesis of claim 21 , wherein the lattice is configured to allow further expansion beyond the second diameter after the primary prosthesis is deployed within the lattice.25. The ...

DIAMETRICALLY ADJUSTABLE ENDOPROSTHESES AND ASSOCIATED SYSTEMS AND METHODS

A diametrically adjustable endoprosthesis includes a controlled expansion element extending along at least a portion of a graft and is supported by a stent. The controlled expansion element diametrically constrains and limits expansion of the endoprosthesis. Upon deployment from a smaller, delivery configuration, the endoprosthesis can expand to the initial diameter set by the controlled expansion element. Thereafter, the endoprosthesis can be further diametrically expanded (e.g., using balloon dilation) by mechanically altering the controlled expansion element. 1. A diametrically adjustable endoprosthesis comprising:a stent-graft including a stent and a base graft secured to the stent, the base graft having a first end and a second end and the stent-graft being self-expanding and exhibiting a self-expansion force, the stent-graft having a maximum diametric expansion limit; anda controlled expansion element having a continuous wall, the controlled expansion element having an initial diametric expansion limit and being adjustable to an adjusted diameter in a range of diameters between the initial diametric expansion limit and the maximum diametric expansion limit when placed under an expansion force in addition to the self-expansion force of the stent-graft, the controlled expansion element being configured to maintain the adjusted diameter under physiological conditions following removal of the expansion force and the stent-graft being configured to limit the range of diameters for the adjusted diameter to the maximum diametric expansion limit.2. The endoprosthesis of claim 1 , wherein the controlled expansion element defines a sliding interface with the stent-graft such that during diametric expansion of the endoprosthesis claim 1 , the sliding interface between the controlled expansion element and the stent-graft permits at least a portion of the controlled expansion element to change in longitudinal dimension at a different rate than the stent-graft at the ...

Endovascular grafts and methods for extended aortic repair

An endovascular graft including a stent graft and a surgical graft is provided. The stent graft can include an elongated body having a collapsed and expanded configuration and include a frame structure covered by a compression sleeve that retains the elongated body in the collapsed configuration until deployment of the stent graft. The endovascular graft can include a first cuff member sized and dimensioned to extend into a lumen of an aortic arch branch vessel when the endovascular graft is implanted in a subject. The frame structure can include a backstop sized and dimensioned to extend into the first cuff member when the endovascular graft is implanted in the subject. The surgical graft can be partially attached to the stent graft at a proximal end portion thereof.

Delivery System And Method For Self-Centering A Proximal End Of A Stent Graft

A method for implanting a prosthesis centrally within a curved lumen includes loading a prosthesis into a delivery sheath, advancing the sheath in a patient towards the curved lumen to place at least the proximal end of the prosthesis within the curved lumen, and centering the proximal end of the prosthesis and/or the distal end of the sheath within the curved lumen. In a first advancing step, the outer catheter containing the inner sheath is advanced together towards the curved lumen to a location proximal of the curved lumen and, in a second advancing step, the inner sheath containing the prosthesis is advanced into the curved lumen to place at least the proximal end within the curved lumen while the outer catheter substantially remains at the location. After centering, the proximal end of the prosthesis is deployed centered within the curved lumen. 1loading a prosthesis into a delivery sheath, the prosthesis having a roximal end and the sheath having a distal end;advancing the sheath in a patient towards the curved lumen to place at least the proximal end within the curved lumen; andsubstantially aligning an inflow plane, which is defined by the proximal end of the prosthesis to be implanted in a patient, with an implant plane, which is defined by a ring of tissue inside a vessel at which the proximal end of the prosthesis is to be implanted, in a common plane that is transverse to a major longitudinal axis of the vessel.. A method for implanting a prosthesis centrally within a curved lumen, which comprises: This application is a continuation of U.S. patent application Ser. No. 14/575,673, filed Dec. 18, 2014, which is a continuation of U.S. patent application Ser. No. 13/024,882, filed Feb. 10, 2011, now abandoned, which is a continuation of U.S. patent application Ser. No. 11/701,876, filed Feb. 1, 2007, now abandoned, which claims the benefit under 35 U.S.C. § 119(e) of U.S. Provisional Application No. 60/851,282, filed Oct. 12, 2006, 60/833,533, filed Jul. 26 ...

CATHETER WITH INTEGRATED EMBOLIC PROTECTION DEVICE

A prosthetic heart valve delivery catheter includes an embolic filter to provide integrated embolic protection to inhibit the release of emboli into the aorta, the aortic arch or branch vessels, and other vasculature during transvascular heart valve replacement procedures. The embolic filter will usually be fixedly or movably attached to a shaft of the delivery catheter proximal of the prosthetic heart valve. 1. A prosthetic heart valve delivery catheter having integrated embolic protection , said catheter comprising:a catheter shaft having a distal portion;an expandable balloon on the distal portion of the catheter shafta prosthetic valve disposed on the expandable balloon on the distal portion of the catheter shaft; andan embolic filter disposed on the distal portion of the shaft at a location proximal of the prosthetic valve, said embolic filter having a collapsed configuration and a deployed configuration wherein an outer periphery of the filter is configured to contact a blood vessel wall;wherein the embolic filter comprises a filter structure having a narrow end coupled to the shaft and an open end located distally of the narrow end.2. The catheter of claim 1 , wherein the narrow end of the filter structure is fixedly attached to the catheter shaft.3. The catheter of claim 1 , wherein the narrow end of the filter structure is slidably mounted on the catheter shaft.4. The catheter of claim 3 , further comprising a proximal stop on the catheter shaft for limiting proximal movement of the embolic filter on the distal portion of the catheter shaft.5. The catheter of claim 4 , further comprising a distal stop on the catheter shaft for limiting distal movement of the embolic filter on the distal portion of the catheter shaft.6. The catheter of claim 1 , wherein the filter comprises a filter membrane and a support structure.7. The catheter of claim 6 , wherein the support structure comprises a plurality of self-expanding axial struts connected at their proximal ends ...

FEMALE URINARY INCONTINENCE DEVICE

A device is provided for applying pressure on a vaginal wall of a female subject, said device being configured for insertion into a vaginal cavity of said female subject. The device includes a first deformable element, a second deformable element and a transmission element. The first deformable element has a resting-state and at least one deformed state and is configured for undergoing deformation in response to an inner body pressure. When in the resting state, the first deformable element is configured to anchor the device inside the vaginal cavity. The second deformable element has a resting-state and at least one deformed state, and is configured for undergoing deformation to apply a second pressure on the vaginal wall, such second pressure being operable to narrow a urethral portion the female subject. The transmission element has a first end connected to the first deformable element and a second end connected to the second deformable element, and is configured for converting the deformation of the first deformable element to a deformation of the second deformable element, and for returning the first and second deformable elements to their respective resting states. 1. A device for applying pressure on a vaginal wall of a female subject , said device being configured for insertion into a vaginal cavity of said female subject , the device comprising:a first deformable element having a resting-state and at least one deformed state, said first deformable element configured to anchor said device when in said resting-state inside the vaginal cavity and for undergoing deformation in response to an inner body pressure;a second deformable element having a resting-state and at least one deformed state, said second deformable element configured for undergoing deformation to apply a second pressure on said vaginal wall operable to narrow an urethral portion said female subject; anda transmission element having a first end connected to said first deformable element and a ...

Pulmonary Airflow

Devices, systems, and methods for improving airflow within an airway. One example embodiment includes a method for treating a subject. The method includes (1) placing an expandable object into one or more airways of the bronchial tree of the subject, (2) expanding the expandable object within at least one of the one or more airways such that at least a portion of a wall of the one or more airways is expanded, and (3) placing a stent in the airway such that a portion of the stent is adjacent to the portion of the wall of the one or more expanded airways. 1. A method comprising:identifying a particular portion of an emphysematous lung;expanding the size of one or more airways connected to the particular portion of the emphysematous lung; andcausing the expanded size of the one or more airways to be maintained.2. The method of claim 1 , wherein expanding the size of the one or more airways connected to the particular portion of the emphysematous lung comprises:placing an expandable object into the one or more airways connected to the particular portion of the emphysematous lung; andafter placing the expandable object, expanding the expandable object.3. The method of claim 1 , wherein causing the expanded size of the one or more airways to be maintained comprises placing a stent within at least a portion of the one or more airways.4. The method of claim 3 , wherein the stent is an open-form stent.5. The method of claim 4 , wherein claim 4 , when the open-form stent is placed within at least the portion of the one or more airways claim 4 , no portion of the open-form stent entirely isolates a given area of a wall of the one or more airways.6. The method of claim 4 , wherein claim 4 , when the open-form stent is placed within at least the portion of the one or more airways claim 4 , the open-form stent does not totally block a mucocilliary structure of the one or more airways in any one direction.7. The method of claim 3 , wherein the stent comprises a diameter of between ...

DIAMETRICALLY ADJUSTABLE ENDOPROSTHESES AND ASSOCIATED SYSTEMS AND METHODS

A diametrically adjustable endoprosthesis includes a controlled expansion element extending along at least a portion of a graft and is supported by a stent. The controlled expansion element diametrically constrains and limits expansion of the endoprosthesis. Upon deployment from a smaller, delivery configuration, the endoprosthesis can expand to the initial diameter set by the controlled expansion element. Thereafter, the endoprosthesis can be further diametrically expanded (e.g., using balloon dilation) by mechanically altering the controlled expansion element. 1. A diametrically adjustable endoprosthesis comprising:a stent-graft including a stent and a base graft secured to the stent, the base graft having a first end and a second end and the stent-graft being self-expanding and exhibiting a self-expansion force, the stent-graft having a maximum diametric expansion limit; anda controlled expansion element having a continuous wall, the controlled expansion element having an initial diametric expansion limit and being adjustable to an adjusted diameter in a range of diameters between the initial diametric expansion limit and the maximum diametric expansion limit when placed under an expansion force in addition to the self-expansion force of the stent-graft, the controlled expansion element being configured to maintain the adjusted diameter under physiological conditions following removal of the expansion force and the stent-graft being configured to limit the range of diameters for the adjusted diameter to the maximum diametric expansion limit.2. The endoprosthesis of claim 1 , wherein the controlled expansion element defines a sliding interface with the stent-graft such that during diametric expansion of the endoprosthesis claim 1 , the sliding interface between the controlled expansion element and the stent-graft permits at least a portion of the controlled expansion element to change in longitudinal dimension at a different rate than the stent-graft at the ...

TRANSCATHETER VALVE REPAIR HAVING IMPROVED PARAVALVULAR SEAL

A transcatheter valve assembly replacement device includes a paravalvular seal that includes outwardly extending fibers that create a seal with the annulus when the valve assembly is deployed. 110-. (canceled)11. A transcatheter valve assembly comprising:an outer frame, wherein the outer frame is formed from a metallic material and defines an open cell configuration;an inner frame that engages a prosthetic heart valve having prosthetic leaflets, wherein the inner frame includes a cylindrically extending inner graft covering extending at least partially radially outwardly of the prosthetic heart valve and radially inwardly of the outer frame for providing sealing to the prosthetic heart valve,wherein the outer frame is secured to the inner graft covering by stitching at a proximal end of the outer frame;an outer seal for preventing paravalvular leaks that extends over at least two rows of cells formed in the outer frame,wherein the outer seal is formed of outwardly extending fibers positioned externally to the outer frame,wherein the valve assembly has a radially compressed orientation and a radially expanded orientation,wherein the valve assembly is configured to press some of the fibers against native leaflets of the aorta of the patient.12. The valve assembly of claim 11 , wherein the outwardly extending fibers include arcuate fibers that overlap in a circumferential direction relative to the outer frame with other arcuate fibers before deployment of the valve assembly.13. The valve assembly of claim 11 , wherein the outwardly extending fibers include spacing between adjacent fibers that forms an opening that extends through a thickness of the outer seal to the outer frame claim 11 , wherein a porosity of the outer seal decreases when the outwardly extending fibers are compressed and at least partially cover the opening.14. The valve assembly of claim 11 ,wherein a height of a fiber of the outwardly extending fibers is greater than a thickness of the outer frame15 ...

STENT GRAFT WITH TOP MESH STENT

Stent grafts and methods of deployment thereof are provided. The stent graft includes a tubular graft body having a graft wall defining a lumen extending between first and second end openings. A stent structure is coupled along the graft wall. A top stent includes a first portion coupled along an inner surface of the graft body at attachment locations, and a second portion extending beyond the first end opening outside of the graft body. The attachment locations are circumferentially spaced from one another in an annular pattern. An end of the stent structure is spaced from the first end opening by a clearance length. When the stent graft is in the radially expanded configuration, the first portion retracts to a retracted length from an extended length, and a portion of the second portion has a greater cross-sectional area and a different cross-sectional shape than the graft body. 1. A stent graft having a radially compressed configuration and a radially expanded configuration , comprising:a tubular graft body having a first end opening and a second end opening;a stent structure coupled along the graft body, wherein an end of the stent structure that is in closest proximity to the first end opening of the graft body is spaced from said first end opening to define a clearance region of the graft body; andan annular mesh top stent having a first portion coupled along an inner surface of the graft body along the clearance region below the first end opening at attachment locations, and a second portion extending beyond the first end opening outside of the graft body,wherein, during radial expansion, the first portion is retracted to a retracted longitudinal length, and the second portion expands to a bulbous shape having a greater cross-sectional area than the first portion, wherein the attachment locations are circumferentially spaced from one another at non-axially adjacent locations, whereby tearing of the graft body is inhibited during retraction of the annular mesh ...

Replacement heart valve

A replacement heart valve assembly has a stent frame and a replacement valve. The replacement valve has a plurality of leaflets and a valve frame. The leaflets are attached to the valve frame. Further, the assembly has a plurality of suspension struts attached to the stent frame and the valve frame. The valve frame is suspended within the stent frame via the suspension struts. In some embodiments, the assembly further has a sealing member attached to the stent frame to prevent leakage around the replacement heart valve assembly.

REPLACEMENT HEART VALVE

A replacement heart valve assembly has a stent frame and a replacement valve. The replacement valve has a plurality of leaflets and a valve frame. The leaflets are attached to the valve frame. Further, the assembly has a plurality of suspension struts attached to the stent frame and the valve frame. The valve frame is suspended within the stent frame via the suspension struts. In some embodiments, the assembly further has a sealing member attached to the stent frame to prevent leakage around the replacement heart valve assembly. 120. The replacement valve assembly of claim , wherein the first tubular frame has a non-uniform thickness. This Application is a continuation of U.S. application Ser. No. 15/884,464, filed Jan. 31, 2018, which is a continuation of Ser. No. 13/920, 847, filed Jun. 18, 2013, which claims the benefit of and priority to U.S. Provisional Application No. 61/661,586, filed Jun. 19, 2012, the entire contents of which are herein incorporated by reference.Not Applicable.It is known that heart valve insufficiency, stenosis, and defects can result in mortality of a patient. Heretofore, a variety of methods and devices have been designed to allay such conditions. One particular option is to use a replacement heart valve. Moreover, various types of replacement heart valves are implanted via minimally invasive techniques, for example transcatheter implantation.One particular type of congenital defect is a bicuspid aortic valve. Bicuspid aortic valves are present in approximately 1%-2% of the general population and can lead to additional heart complications. C. Ward, Clinical Significance of the Bicuspid Aortic Valve, 83 Heart 81, 82 (2000). For example, approximately 50% of adults affected by severe aortic stenosis have a bicuspid aortic valve. Id.In addition, while existing technologies offer some solutions for patients suffering from stenosis and/or valve insufficiency, these existing technologies suffer from a number of problems in bicuspid aortic ...

METHODS AND DEVICES FOR HEART VALVE REPAIR

A system for reshaping a valve annulus includes an elongate template having a length along a longitudinal axis and at least one concavity in a generally lateral direction along said length. The pre-shaped template is positioned against at least a region of an inner peripheral wall of the valve annulus, and at least one anchor on the template is advanced into a lateral wall of the valve annulus to reposition at least one segment of the region of the inner peripheral wall of the valve annulus into said concavity. In this way, a peripheral length of the valve annulus can be foreshortened and/or reshaped to improve coaption of the valve leaflets and/or to eliminate or decrease regurgitation of a valve. 1. A stent prosthesis for valve repair or replacement comprising:a scaffold comprising patterned structural elements, said stent being expandable from a crimped configuration to an expanded configuration and having sufficient strength to support a body annulus in the expanded configurations, wherein the scaffold comprises at least one circumferential ring comprising struts and crowns, wherein at least one strut in said at least one ring comprises at least one separation region and wherein said at least one separation region comprises a male-female junction and a biodegradable polymer and/or adhesive, said separation region being held together in the crimped configuration and is configured to separate after expansion of the stent under physiologic environment; andat least one valve configured to be coupled to said at least one ring, said valve allowing blood to flow in one direction during the cardiac cycle.2. An implant for reshaping a valve annulus , said implant comprising:a pre-shaped metallic template having a length in an axial direction and at least one concavity in a lateral direction along said length, said concavity having a concave surface configured to be positioned adjacent to a peripheral wall of the valve annulus; andat least one anchor configured to be ...

Stents with improved fixation

The present disclosure provides stents, particularly self-expanding stents, useful for the GI tract, and more particularly, useful for treating esophageal strictures. The stents provided herein include a medial region and proximal and distal cuffs having external diameters greater than the medial region diameter when the stent is in the deployed state. The medial region comprises an open weave wire construction. An elastomeric coating circumscribes the medial region, while the may be an extension of the wire construction or separate elements. Preferably, the cuffs have a textured surface for contact with the esophageal wall tissue to resist stent migration. The elastomer coated medial region provides a barrier to tissue ingrowth, and has an enhanced radial restoring force to maintain an open passageway in a body lumen. Optionally, the stent includes an exterior sheath with a surface pattern, to which the stent couples. A low durometer sleeve, between the stent and body lumen, axial positioning of the stent relative to the body lumen. Consequently, precision in stent placement is provided without tissue damage that could result if positioning motion occurred between the surface texture and the body lumen.

PROSTHETIC VALVE SUPPORT STRUCTURE

The present invention is directed to prostheses including a support structure having a proximal end and a distal end, and a motion limiting member attached to the distal end of the support structure, wherein the motion limiting member is configured to restrict radial expansion of the distal end of the support structure. Methods for delivering the prosthesis are also provided. 1. (canceled)2. A prosthesis comprising:a support structure having a proximal portion and a distal portion; anda motion limiting member attached to the distal portion of the support structure,wherein, when deployed, the motion limiting member restricts radial expansion of the distal portion of the support structure,wherein the motion limiting member comprises a rigid circular frame.3. The prosthesis of claim 2 , wherein the support structure comprises a plurality of posts at a distal portion thereof claim 2 , andwherein the rigid circular frame is attached to a distal end of each of the plurality of posts.48-. (canceled)9. A prosthesis comprising:a support structure having a proximal portion and a distal portion; anda motion limiting member attached to the distal portion of the support structure,wherein, when deployed, the motion limiting member restricts radial expansion of the distal portion of the support structure,wherein the support structure comprises a plurality of posts at the distal portion thereof, andwherein the motion limiting member comprises a plurality of linear support elements, each linear support element extending between adjacent posts of the plurality of posts.10. The prosthesis of claim 9 , wherein each linear support element is attached to distal ends of the adjacent posts.11. The prosthesis of claim 9 , wherein each linear support element is formed of a non-rigid material.12. The prosthesis of claim 9 , wherein each linear support element is formed of a rigid material.13. The prosthesis of claim 9 , wherein each linear support element comprises a plurality of linear ...

SYSTEMS FOR REPLACING A NATIVE HEART VALVE AND AORTA WITH A PROSTHETIC HEART VALVE AND CONDUIT

A medical device includes an expandable conduit, a prosthetic heart valve and a delivery device, including a balloon catheter. The expandable conduit may include one or more inner or outer sleeves supported by a frame or stent. The sleeve(s) may be a bioprosthetic tissue wrapped, molded or sewn about the frame or stent. Coupled to an end of the expandable conduit is the prosthetic heart valve. The conduit and heart valve may be crimped on the balloon catheter for percutaneous deployment. The frame may be constructed of a balloon-expandable material for the conduit portion and a self-expandable material for the prosthetic heart valve portion. The prosthetic heart valve is anchored at the native heart valve and then the conduit to be expanded into place to protect the aorta. The self-expanding prosthetic heart valve avoids the need for balloon mounting. This provides for a smaller diameter and easier delivery. 1. A system for use in replacing a native aortic heart valve and repairing a defect in a section of the aorta contiguous with the native aortic heart valve , the system comprising:a catheter having a balloon thereon;a retractable sheath defining an interior portion into which at least the prosthetic valve is compressed radially inwardly a self-expandable prosthetic valve located at the first end compressed radially inwardly and held in a delivery state by the retractable sheath and configured to expand in a radially outward direction to frictionally engage at least a portion of the native heart valve;', 'an aortic conduit comprising a balloon-expandable tubular frame and a tubular sleeve extending axially along and against the balloon-expandable frame, the aortic conduit being coupled to an end of the prosthetic valve and crimped around the balloon, the balloon extending along the conduit but not within the prosthetic valve., 'a medical device sleeved over the catheter having a length sufficient to extend from a first end secured at the native aortic heart valve ...

Actively controllable heart valve implant and method of controlling same

A method of implanting a replacement mitral valve can include expanding a replacement mitral valve to a first expanded configuration. The replacement mitral valve can include a force-expanding mitral valve lattice and a self-expanding valve trampoline lattice. The mitral valve lattice has an inflow end portion and an outflow end portion, and the valve trampoline lattice is attached to the outflow end portion of the mitral valve lattice. The method can also include rotating a plurality of jack screws connected to the mitral valve lattice. The jack screws can be configured to expand the mitral valve lattice from the first expanded configuration to a second expanded configuration.

METHOD FOR STABILIZING A CARDIAC VALVE ANNULUS

A method for stabilizing a cardiac valve annulus is provided. The method includes intravascularly delivering a prosthesis to a region of a cardiac valve, expanding the prosthesis to secure the prosthesis to the region of the cardiac valve, and reducing the inner diameter of the prosthesis to form the region of the cardiac valve into a predefined shape. 120-. (canceled)21. A method for reshaping a heart valve comprising:positioning a prosthesis in a compressed configuration at a location of the heart valve, the prosthesis including a ring and a plurality of anchor members adjacent an end of the ring;expanding the prosthesis to a deployment configuration;driving the anchor members into tissue surrounding the heart valve; andafter the prosthesis is expanded with the anchors in the tissue, reducing an inner diameter of the prosthesis to a resting configuration to reshape the valve annulus,wherein the prosthesis in the radially compressed configuration has a first diameter smaller than a second diameter of the prosthesis in the resting configuration which is smaller than a third diameter of the prosthesis in the deployment configuration.22. The method of claim 21 , wherein the ring is formed of a shape memory material.23. The method of claim 22 , wherein the step of reducing the inner diameter of the ring to the resting configuration is achieved by the ring self-contracting to the resting configuration due to the shape-memory material.24. The method of claim 21 , wherein with the prosthesis in the compressed configuration the anchor members are parallel with a central longitudinal axis of the ring.25. The method of claim 21 , wherein the ring is a serpentine ring including a plurality of struts joined together by a plurality of apexes.26. The method of claim 21 , wherein the anchor members comprise barbs.27. The method of claim 21 , wherein the anchor members are disposed only at a distal end of the ring.28. The method of claim 21 , wherein the ring is a closed ring.29. ...

Personalized prosthesis and methods of use

A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.

Lattice

The invention relates to medical devices and methods of using them. The devices are prostheses which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The prostheses are configured to have a lattice resistant to dilation and creep, which is defined by a plurality of openings. The prosthesis may also optionally have a stent disposed proximal to the lattice. In exemplary embodiments, the fluoropolymer is expanded polytetrafluoroethylene. The composite materials exhibit high elongation while substantially retaining the strength properties of the fluoropolymer membrane. In at least one embodiment, the lattice is made of a composite material that includes a least one fluoropolymer membrane including serpentine fibrils and an elastomer. A lattice including a generally tubular member formed of a composite material including a least one fluoropolymer membrane containing serpentine fibrils and an elastomer is also provided.

Heart chamber prosthetic valve implant with base, mesh and dome sections with single chamber anchoring for preservation, supplementation and/or replacement of native valve function

Various embodiments of the present invention comprise a single-chamber collapsible and expandable prosthetic valve implant device comprising the following capabilities: (1) preservation of native valve functionality; (2) initial preservation of native valve functionality with subsequent full replacement of native valve functionality; (3) full replacement of native valve functionality; and/or (4) mitigation of the prolapsing distance of the dysfunctional leaflets by preventing the anterior excursion of the prolapsing leaflets above the upper annular surface and into the left atrial chamber in order to preserve native leaflet functionality for as long as possible. The expanded and implanted device does not extend beyond the boundaries of the subject heart chamber, e.g., the left atrium, thereby enabling the preservation of any remaining native valve functionality with subsequent full replacement of native valve functionality if and when needed.

METHOD AND APPARATUS FOR CREATING A MODIFIED TISSUE GRAFT

In a method of creating a modified tissue graft, at least one exterior surface of a graft is modified by compressing, cutting and/or removing one or more portions thereof, such as to create designed surface features which cause the tissue graft to have characteristics for a specific anatomical area. The modified tissue graft may comprise a medicated graft, such as by associating medicants with the surface features, or by associating a second graft or layer with a modified base tissue graft layer, where medicants are associated with the second graft or layer. The tissue graft may be modified by pressing a specially configured template or die, such as having blades thereon, into the tissue graft, such as to create a pattern of partial depth cuts. 1. A multi-layer , medicated , reconstructive tissue graft comprising:a base tissue graft having a top surface and a bottom surface, said base tissue graft modified by compressing, cutting and/or removing one or more portions of either or both said top surface and said bottom surface to create one or more designed surface features;a second graft layer or sheet applied to either or both said top surface and said bottom surface of said base tissue graft; andone or more medicants associated with said multi-layer reconstructive graft.2. The multi-layer graft in accordance with claim 1 , wherein said one or more medicants are associated with said designed surface features and said second graft layer is placed over said designed surface features.3. The multi-layer graft in accordance with claim 1 , wherein said medicants are associated with said second graft layer or sheet.4. The multi-layer graft in accordance with claim 3 , wherein said second graft layer or sheet comprises a amnion membrane allograft and said one or more medicants are associated with said allograft.5. The multi-layer graft in accordance with claim 3 , wherein said second graft layer or sheet comprises a sheet and said medicants are associated with said sheet.6. ...

Expandable vascular implant

The invention relates to an expandable vascular implant for implantation into vessels of a patient, the vascular implant being convertible from a compressed state to an expanded state, and the vascular implant comprising the following: a hollow cylindrical main body having a longitudinal direction and a proximal end and a distal end, and a main body lumen which extends from the proximal to the distal end. The hollow cylindrical main body is formed by a tubular lattice structure, the tubular lattice structure having at least one first and at least one second region, the first region being fixedly connected to the second region, the first region being designed to be self-expandable, and the second region is designed to be balloon-dilatable.

Prosthetic mitral valve with improved atrial and/or annular apposition and paravalvular leakage mitigation

The present invention provides a prosthetic heart valve device with improved fit and/or apposition between the device frame and left atrial tissue and/or the device base and the annular tissue of the left atrium to improve shifting of the implanted device and/or mitigate paravalvular leakage. The improved fit and/or apposition arises in various embodiments by providing or allowing an asymmetrical frame and/or frame base and/or providing a lower lip to aid in conforming to the asymmetrical shape of the atrium and/or ensure firm positioning therein. An additional benefit of these arrangement(s) is mitigation of paravalvular leakage as a result of improved fit and seal. In certain embodiments, the asymmetry of the frame assists with delivery of the device into the atrium.

TRANSCATHETER VALVE REPAIR HAVING IMPROVED PARAVALVULAR SEAL

A transcatheter valve assembly replacement device includes an improved paravalvular seal. 1. An endograft device for endovascular repair of ascending aortic aneurysms , comprising:a first endograft prosthetic component comprising (i) a proximal frame, and (ii) a distal frame secured to the proximal frame and extending to a distal end of the first prosthetic component,at least one conduit secured to the first prosthetic component and positioned adjacent to the proximal frame,a second prosthetic component secured to a proximal end of the first prosthetic component, the second prosthetic component comprising (i) a balloon-expandable frame extending distally from a proximal end of the second prosthetic component, and (ii) a self-expanding frame connected to the balloon-expandable frame and extending to a distal end of the second prosthetic component, anda valve element secured to the balloon-expandable frame at the proximal end of the second prosthetic component.2. The endograft device of claim 1 , wherein the self-expanding frame has an hourglass shape.3. The endograft device of claim 2 , wherein the self-expanding frame includes:a first section that tapers inwardly between a proximal end and a distal end, anda second section having a proximal end that is connected to the distal end of the first section, the second section tapering outwardly between the proximal end of the second section and a distal end of the second section.4. The endograft device of claim 3 , wherein the proximal end of the first section is secured to a distal end of the balloon-expandable frame.5. The endograft device of claim 3 , wherein:the self-expanding frame includes a third section extending proximally from the proximal end of the first section, the third section having a passageway defined therein, andthe balloon-expandable frame is positioned in the passageway of the third section of the self-expanding frame.6. The endograft device of claim 5 , wherein the balloon-expandable frame is ...

Tapered helical coil bronchial valve

This disclosure concerns systems and methods for tissue volume reduction and control of the flow of substances through the body. Systems according to the various embodiments of the disclosure include check valves formed from wire coils which are deployable through a tubular lumen, such as the working channel of an endoscope, or a catheter.

Multi-chambered breast tissue expander

A tissue expansion device with a plurality of lobes made from non-compliant material, each lobe defining a chamber therein. Each chamber is fluidly isolated from every other chamber in the plurality of lobes. Each chamber has an inflation element with a valve to release a pressurized fluid to inflate the lobe to expand a cavity, and a deflation element with a valve to deflate the lobe by compressing the fluid.

DEVICE AND METHOD FOR AN IMPLANT

A novel and advantageous implant device and methods for implanting the device are provided. Particularly, novel and advantageous devices and methods for breast reconstruction are provided. More particularly, novel and advantageous devices and methods for breast reconstruction to provide a more realistic form are provided. 1. A system for breast reconstruction comprising: an expander portion configured to receive a fluid and expand upon receiving the fluid; and', 'a nub comprising a substantially rigid protrusion, the nub extending outwardly from the expander portion when the expander is in an expanded configuration; and, 'an expansion implant comprising a breast portion; and', 'a nipple portion extending outwardly from the breast portion., 'a reconstruction implant comprising2. The system of claim 1 , wherein the expansion implant further comprises a port for accessing an interior of the expander portion.3. The system of claim 1 , wherein the expander portion has a round shape.4. The system of claim 1 , wherein the expansion implant and the reconstruction implant have complimentary shapes.5. The system of claim 4 , wherein the expansion implant and the reconstruction implant have anatomical shapes.6. The system of claim 1 , wherein the nub does not extend outwardly from the expander portion when the expander portion does not contain fluid.7. The system of claim 1 , wherein the nub emulates a human nipple.8. The system of claim 1 , wherein the nub is integral with the expander portion.9. The system of claim 1 , wherein the nub is coupled to the expander portion.10. The system of claim 1 , wherein an outward facing surface of the breast portion is textured.11. The system of claim 1 , wherein the nipple portion is integral with the breast portion.12. The system of claim 1 , wherein the nipple portion is coupled the breast portion.13. An expansion implant comprising:an expander portion configured to receive a fluid and expand upon receiving the fluid;a nub comprising a ...

UNIVERSAL HEART VALVE DEVICE

Embodiments of universal self-anchoring prosthetic valves for multi-position transcatheter or surgical implantation within any diseased or malfunctioning native heart valve are provided. An exemplary embodiment of a prosthetic valve includes a radially compressible and self-expanding central core housing a prosthetic valve, with compressible and flexible memory-shaped woven wire anchoring discs at the inflow and outflow ends. Specific design properties allow the prosthesis to be conformable, self-centering and flipped for multiple appropriate physiologic implant orientations. Expansive transverse radial force exerted by the central core, and memory-shape induced directional forces exerted by flexible inflow and outflow discs, capture and compress native peri-annular and leaflet tissues to anchor the prosthesis. Tissue facing frame surfaces may include small tines to enhance anchoring. The prosthetic valve frames may include various biomaterials or polymers as linings, coatings or coverings to enhance sealing. Methods and devices for delivering and implanting the valve based on access are described. 1. A sutureless universal heart valve device comprising:a frame having an inflow disc, a central core defining a central orifice, and an outflow disc, wherein the frame is self-expanding or balloon dilatable;a plurality of tines disposed on the frame for engaging native tissue, wherein the plurality of tines are disposed on native tissue facing surfaces of the frame; anda prosthetic valve housed in the central orifice, wherein the prosthetic valve is a one-way valve and comprises bioprosthetic or polymeric materials,wherein the central core is radially compressible and self-expanding memory-shaped wire or balloon expandable open cell wire,wherein the inflow and outflow discs are compressible and flexible memory-shaped woven wire or balloon expandable open cell wire,wherein the inflow disc has a larger diameter than the outflow disc, andwherein the inflow disc, central ...

UNCAGING STENT

A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment. 1. An endoluminal prosthesis comprising:a scaffold having a plurality of circumferential rings patterned from a non-degradable material, said scaffold being configured to expand from a crimped configuration to an expanded configuration, wherein attachment points on at least some adjacent circumferential rings are joined by circumferentially separable axial links;wherein at least some of the axial links comprise a first segment and a second segment, wherein the first and second segments are divided by an axially extending dividing line, are circumferentially interlocked to inhibit circumferential separation thereof while the scaffold is in the crimped configuration, and are configured to deform to circumferentially unlock when the scaffold is in the expanded configuration; andwherein the circumferential rings separate at the attachment points while each segment of the axial link remains attached to said attachment points after the segments have unlocked.2. An endoluminal prosthesis as in claim 1 , wherein the circumferentially separable axial links extend between crowns on adjacent circumferential rings.3. An endoluminal prosthesis as in claim 1 , wherein the circumferentially separable axial links extend between struts on adjacent circumferential rings.4. An endoluminal prosthesis as in claim 1 , wherein the circumferentially separable axial links extend between a crown on one circumferential rings and a struts on an adjacent circumferential rings.5. An endoluminal prosthesis as in claim 1 , wherein said at least some axial links are arranged in an axial line along the scaffold.6. An endoluminal ...

Auxetic stents for managing venous stenosis

Stents useable for treating venous stenosis are disclosed. In embodiments, a stent is configured to be auxetic, expanding axially as it is expanded radially, to prevent the imposition of tension on portions of a blood vessel adjacent to the stented portion of the blood vessel, and thereby prevent a narrowing of the adjacent portions and improving luminal gain. The stent may include one or more cross members that are deformable axially, to allow the axial length of the stent to be adjusted while maintaining a constant diameter, and further to allow the stent to be curved to conform to vessel curvature.

A Flow Regulating Device In The Heart

A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element. 1100. A blood flow regulator () for creating a shunt in the heart , comprising;{'b': 101', '103, 'a proximal element () having a general disc-shape, defined by a braid of one or more wires extending about a central aperture () of the proximal element;'}{'b': 102', '104, 'a distal element () having a general disc-shape, defined by a braid of one or more wires extending about a central aperture () of the distal element; and'}{'b': 105', '106, 'a third element () defining a neck section intermediate the proximal and distal elements and forming a cavity () having a diameter no greater than a diameter of each of the distal and proximal elements,'}{'b': 107', '108, 'wherein said distal element comprises at least one loop () of a wire extending radially outwardly from a center () of the distal element and returning towards said center of said distal element.'}2. Blood flow regulator according to claim 1 , wherein said proximal element claim 1 , said distal element claim 1 , and said third element are formed of the same braiding of one or more wires.3109107. Blood flow regulator according to claim 2 , wherein said proximal element comprises a connecting element () for a delivery device claim 2 , wherein ends of said one or more wires ...

METHOD AND APPARATUS FOR CREATING A RECONSTRUCTIVE GRAFT

A method and apparatus is provided for creating an internal reconstruction tissue graft. Templates may be used to create a multitude of patterns in a variety of tissue reconstruction grafts. An apparatus may be used to create an internal tissue graft for reconstruction through either compression and/or removal of segments. An apparatus may be used, through either compression and or removal of segments of a preformed template made of synthetics and or metal that mirrors a template that can be used as an internal tissue graft for reconstruction. In a method, such as using software analysis and an apparatus, the physical properties of the tissue graft and its pre- and post-operative properties and appearance may be measured. 1. A reconstructive tissue graft for placement at an anatomical site of a human , said reconstructive tissue graft prepared by a process comprising the steps of:obtaining a human tissue graft from a site other than said anatomical site at which said reconstructive tissue graft is to be placed;modifying an exterior surface of said tissue graft to include a designed surface feature, said designed surface feature changing said exterior surface of said tissue graft to define a location for accepting at least one secondary material; andassociating said at least one secondary material with said designed surface feature, said at least one secondary material comprising at least one of a medicant and a secondary tissue.2. The reconstructive tissue graft in accordance with wherein said human tissue graft comprises cadaveric human tissue.3. The reconstructive tissue graft in accordance with wherein said medicant comprises one or more of an antibiotic claim 1 , a hormone claim 1 , a growth factor and a chemotherapeutic agent.4. The reconstructive tissue graft in accordance with wherein said secondary tissue comprises one or more of acellular human tissue claim 1 , non-human tissue and stem cells.5. The reconstructive tissue graft in accordance with wherein ...

SYSTEMS FOR REPLACING A NATIVE HEART VALVE AND AORTA WITH A PROSTHETIC HEART VALVE AND CONDUIT

A medical device includes an expandable conduit, a prosthetic heart valve and a delivery device, including a balloon catheter. The expandable conduit may include one or more inner or outer sleeves supported by a frame or stent. The sleeve(s) may be a bioprosthetic tissue wrapped, molded or sewn about the frame or stent. Coupled to an end of the expandable conduit is the prosthetic heart valve. The conduit and heart valve may be crimped on the balloon catheter for percutaneous deployment. The frame may be constructed of an expandable material for the conduit portion and an expandable material for the prosthetic heart valve portion. The prosthetic heart valve can be anchored at the native heart valve and then the conduit can be expanded into place to protect the aorta. 1. A system for use in replacing a native aortic heart valve and repairing a defect in a portion of an aorta , the system comprising:an elongated catheter having a balloon thereon;a retractable sheath defining an interior portion, the sheath being longitudinally movable over the catheter; a prosthetic heart valve located at the first end comprising an expandable/compressible stent, the heart valve being configured to expand in a radially outward direction to frictionally engage at least a portion of the native heart valve, the heart valve having flexible valve leaflets that form a one-way flow structure therethrough;', 'an aortic conduit coupled in series to the heart valve and extending to the second end comprising an expandable/compressible tubular frame and a tubular sleeve extending axially along and against the tubular frame, the aortic conduit being configured to expand in a radially outward direction to frictionally engage at least a portion of the aorta, the aortic conduit being configured to guide high pressure blood flow through the aortic conduit,', 'wherein a first portion of the valved conduit is self-expandable and a second portion is balloon-expandable and the sheath must be retracted ...

DELIVERY SYSTEM FOR IMPLANTABLE MEDICAL DEVICE

A delivery system includes an inflatable delivery balloon formed with a plurality of constraining elements which create constrained regions in a body portion of the balloon, interposed between unconstrained regions. The constrained regions create recesses for receiving a medical device or part of a medical device. The constraining elements are preferably formed by woven or braided material, advantageously embedded within the wall of the inflatable balloon. The constraining elements provide a structure that will not flatten upon inflation of the balloon and also a structure which can readily be folded or wrapped for endoluminal delivery purposes, and which retains flexibility of the delivery device. 1. An endoluminal delivery device including:a catheter unit;a delivery balloon mounted on the catheter unit, the balloon including a body portion and first and second end portions coupled to the catheter unit, the body portion providing a medical device support surface; the delivery balloon being inflatable so as to cause the body portion to expand to an inflated, first diameter;and at least one circumferential constraining element disposed around at least a part of the body portion, the at least one circumferential constraining element acting to constrain inflation of at least one circumferential section of the body portion to a second diameter less than the inflated, first diameter.2. An endoluminal delivery device according to claim 1 , wherein the or each constraining element is in the form of an annular band disposed circumferentially around the body portion.3. An endoluminal delivery device according to claim 2 , wherein the or each constraining element is made of a first material chosen from the group of a woven claim 2 , a knitted claim 2 , and a braided material.4. An endoluminal delivery device according to claim 1 , comprising a plurality of constraining elements claim 1 , disposed along the body portion of the delivery balloon.5. An endoluminal delivery device ...

INTRAOSSEOUS STENT

The invention relates to a self-expanding intraosseous stent () intended to contain intraosseous cement, characterized in that the stent comprises a central part () and two lateral parts () arranged on either side of the central part and extending along the same longitudinal axis (X), and in that the central part has a radial force lower than the radial force of the lateral parts. 114-. (canceled)15. A self-expanding intraosseous stent intended to contain intraosseous cement , wherein the stent comprises a central part and two lateral parts arranged on either side of the central part and extending along the same longitudinal axis , and wherein the central part has a radial force lower than the radial force of the lateral parts.16. The intraosseous stent according to claim 15 , wherein the central part of the stent has a diameter greater than the diameter of the lateral parts of said stent.17. The intraosseous stent according to claim 15 , wherein said stent has a biconical shape.18. The intraosseous stent according to claim 17 , wherein the meshing density of the lateral parts of the biconical stent is greater than the meshing density of the central part of said stent.19. The intraosseous stent according to claim 17 , wherein the ends of the biconical stent are reinforced by a metal ring.20. The intraosseous stent according to claim 15 , wherein the lateral parts of the stent are secured on the central part claim 15 , in particular by welding or meshing entanglement.21. The intraosseous stent according to claim 20 , wherein the meshing density of the lateral parts of the stent is greater than the meshing density of the central part of said stent.22. The intraosseous stent according to claim 15 , wherein the stent comprises a coaxial meshed outer tube and meshed inner tube claim 15 , the inner tube having a length greater than the length of the outer tube claim 15 , so that ends of the inner tube protrude from the outer tube forming the central part of said stent ...

Flow Regulating Device In The Heart

A blood flow regulator for creating a shunt in the heart, comprising; a proximal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the proximal element; a distal element having a general disc-shape, defined by a braid of one or more wires extending about a central aperture of the distal element; and a third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements, wherein said distal element comprises at least one loop of a wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element. 1. A blood flow regulator for creating a shunt in the heart , comprising;a proximal element having a general disc-shape, defined by a braid of more than one wire extending about a central aperture of the proximal element;a distal element having a general disc-shape, defined by a braid of more than one wire extending about a central aperture of the distal element; anda third element defining a neck section intermediate the proximal and distal elements and forming a cavity having a diameter no greater than a diameter of each of the distal and proximal elements,wherein said proximal element, said distal element, and said third element are formed of the same braiding of more than one wire,wherein said distal element comprises returning loops of said more than one wire extending radially outwardly from a center of the distal element and returning towards said center of said distal element, andwherein said proximal element comprises a connecting element for a delivery device, wherein opposite ends of each of said more than one wire forming said distal element are fixed to said connecting element.2. Blood flow regulator according to claim 1 , wherein the braiding at a perimeter of said distal element is folded radially inwards to form ...

Optimised Structure for an Expandable Implant of the Stent or Endoprosthesis Type

An implant includes an optimised structure for implantation in a canal or in a cavity of a living being. The structure includes a tubular structure extending along a longitudinal axis, said structure having at least one braided longitudinal sector of metal wires and open longitudinal ends. The tubular structure has a braided longitudinal sector at each longitudinal end and at least one twisted longitudinal sector, produced with said metal wires in order to form, with continuity, said tubular structure.

CORONARY ARTERY CHECK VALVE

A coronary artery check valve includes a stent configured to attach to an inner wall of a coronary artery of a living subject, and a tapered helical coil coupled to the stent and configured to regulate blood flow in the coronary artery. The coronary artery check valve is configured to prevent retrograde flow of the coronary blood supply during diastole by closing during systole of the heart when the tapered helical coil compresses longitudinally, and opening when the tapered helical coil expands longitudinally to permit blood flow into the coronary artery when a coronary pressure of the living subject drops below diastolic blood pressure. 1. A coronary artery check valve comprising:a stent configured to attach to an inner wall of a coronary artery of a living subject; anda tapered helical coil coupled to the stent, the tapered helical coil configured to regulate blood flow in the coronary artery of the living subject;wherein the coronary artery check valve is configured to prevent retrograde flow of a coronary blood supply during diastole of a heart of the living subject.2. The coronary artery check valve of claim 1 , wherein the coronary artery check valve is configured to prevent retrograde flow of the coronary blood supply during diastole by closing during systole of the heart when the tapered helical coil compresses longitudinally claim 1 , and opening when the tapered helical coil expands longitudinally to permit blood flow into the coronary artery when a coronary pressure of the living subject drops below diastolic blood pressure.3. The coronary artery check valve of claim 1 , wherein the coronary artery check valve is configured for implantation in a coronary ostia of the living subject.4. The coronary artery check valve of claim 1 , wherein the tapered helical coil is formed by a single wire.5. The coronary artery check valve of claim 4 , wherein the single wire comprises nitinol.6. The coronary artery check valve of claim 1 , wherein the tapered helical ...

ENDOVASCULAR PROSTHETIC HEART VALVE REPLACEMENT

A prosthetic aortic valve intended for native or valve-in-valve within bioprostheses includes an expandable support scaffold and valve leaflets disposed within an upper leaflet portion of the support scaffold. The valve leaflets within the upper portion may be located within the annulus (intravalvular), above the annulus, or above the native or prosthetic leaflets (supravalvular). The valve within a previously implanted degenerated heart valve such that a base or lower portion of the replacement valve is within the previously implanted valve and the upper portion is expanded within the aorta, the internal area of the valve can be increased and the hemodynamics of the valve improved. Alternatively, the valve may include separate upper and lower portions allowing the portions to be implanted sequentially and the length and other characteristics of the valve to be adjusted based on patient anatomy and condition. 127-. (canceled)28. A method for implanting a prosthetic aortic valve in a native aortic valve annulus location , said method comprising:providing a replacement aortic prosthetic valve having:a lower base portion comprising an inner tubular wall comprising a metal support scaffold and an outer tubular wall comprising a metal support scaffold, wherein at least a portion of the inner tubular wall is disposed within the outer tubular wall and a separate upper valve portion comprising a lower engagement region and an upper leaflet structure and wherein the outer tubular wall of the lower base portion is adapted to be expanded within a heart valve annulus and conform to the irregularities of shape of the heart valve annulus and the inner tubular wall is adapted to maintain a circular orientation after expansion;positioning the replacement aortic prosthetic valve in the native aortic valve location so that the lower base portion is located within the native aortic valve annulus and the lower engagement region of the upper valve portion is located within the inner ...

DEVICE FOR ENDOVASCULAR AORTIC REPAIR AND METHOD OF USING THE SAME

An intraluminal vascular prosthesis assembly, having a hollow cylindrical body with a first end and a second end is provided. The assembly includes, at its first end, a first vascular prosthesis portion, and at its second end, a second vascular prosthesis portion which has only a prosthesis material. The vascular prosthesis assembly has a stent portion which is provided between the first vascular prosthesis portion and the second vascular prosthesis portion, the stent portion being free of prosthesis material to allow fluid flow therethrough and received within the aortic arch and spanning the brachiocephalic artery, left common carotid artery, and left subclavian artery when placed within the aortic arch of a patient. 1. An intraluminal vascular prosthesis assembly , having a hollow cylindrical body with a first end and a second end , comprising:at its first end, a first vascular prosthesis portion; andat its second end, a second vascular prosthesis portion;wherein the vascular prosthesis assembly has a stent portion provided between the first vascular prosthesis portion and the second vascular prosthesis portion;wherein the stent portion is received within the aortic arch;wherein the stent portion defines a top portion that spans, but does not extend into, the brachiocephalic artery, left common carotid artery, and left subclavian artery when placed within the aortic arch of a patient; andwherein a surface of the stent portion facing the brachiocephalic artery, left common carotid artery, and left subclavian artery is free of graft material to allow fluid flow therethrough.2. The intraluminal vascular prosthesis assembly of claim 1 , wherein the vascular prosthesis assembly is configured for implantation in the aortic arch claim 1 , wherein the vascular prosthesis assembly can be transferred from a compressed state to an expanded state claim 1 , and wherein the first vascular prosthesis portion and the second vascular prosthesis portion are designed for anchoring ...

HYBRID HEART VALVES ADAPTED FOR POST-IMPLANT EXPANSION

A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure. 1. A hybrid prosthetic heart valve adapted for post-implant expansion and having an inflow end and an outflow end , comprising:a valve member including an inner structural support stent having upstanding commissure posts extending in the outflow direction alternating with arcuate inflow cusps, and an inflow end undulating up and down corresponding to the commissure posts and cusps, the support stent defining an implant circumference that is non-compressible in normal physiological use and has a first diameter, and wherein the support stent permits expansion from the first diameter to a second diameter larger than the first diameter upon application of an outward dilatory force from within the support stent substantially larger than forces associated with normal physiological use, and a plurality of flexible leaflets having peripheral edges attached along the commissure posts and inflow cusps of the support stent and configured to ensure one-way blood flow through the valve member; anda plastically-expandable inflow stent frame secured to and projecting from an inflow end of the support stent and having a strength requiring a predetermined expansion force to convert to an expanded ...

SYSTEMS FOR RAPIDLY DEPLOYABLE SURGICAL HEART VALVES

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps. 1. A system for delivering a prosthetic heart valve , comprising:a heart valve including a prosthetic valve and an expandable frame having a contracted state for delivery to an implant position and an expanded state;a valve holder attached to the heart valve and having a through passage; anda handle shaft and balloon catheter assembly packaged separately from the heart valve and valve holder, comprising:a balloon catheter having a balloon; anda handle shaft having a lumen for passage of the balloon catheter and a distal end configured to mate with a proximal end of the valve holder such that the balloon can be advanced distally through the handle shaft, through the valve holder and within the heart valve, and wherein the distal end of the handle shaft and a proximal end of the valve holder have keyed structures that are unique for different sizes of valves such that a handle shaft and balloon catheter assembly for one valve size cannot mate with a valve holder of a different valve size.2. The system of claim 1 , wherein the prosthetic valve has an inner frame assembly defining a non-expandable claim 1 , non- ...

Retractor having a puzzle-type connection

A stent retractor has a radially flexibly expandable tubular sheath divided in the peripheral direction into at least two sections, specifically a reinforcing section and an expanding section, with radial flexibilities that differ from one another, these sections being interconnected integrally. The stent retractor includes axial segments that are connected by a puzzle-type connection allowing simple separation or length adjustment in the axial direction (including when in situ) while also being made integrally, for example by means of a laser or water jet cutting method, preferably from a tubular blank.

Actively Controllable Heart Valve Implant and Method of Controlling Same

A mitral valve implant includes a force-expanding mitral valve lattice having an interior orifice and a self-expanding valve trampoline attached at the interior orifice of the force-expanding mitral valve lattice. The mitral valve lattice is self-expandable to a first configuration and force expandable from the first configuration to a second configuration. The configurations can be circular or D-shaped. The mitral valve lattice comprises jack screws adjusting configurations of the mitral valve lattice. The valve trampoline has a cylindrical central region comprising valve leaflets. An outwardly flaring implant skirt is attached to the mitral valve lattice exterior. Wall-retaining wires are attached to the mitral valve lattice, are petal-shaped, and have a pre-set, radially outward, memory shape. The wires and skirt impart a force on a respective side of the native mitral valve when the mitral valve lattice is expanded within an annulus of the native mitral valve.

SYSTEMS FOR RAPIDLY DEPLOYABLE SURGICAL HEART VALVES

A quick-connect heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The heart valve includes a substantially non-expandable, non-compressible prosthetic valve and a plastically-expandable frame, thereby enabling attachment to the annulus without sutures. A small number of guide sutures may be provided for aortic valve orientation. The prosthetic valve may be a commercially available valve with a sewing ring with the frame attached thereto. The frame may expand from a conical deployment shape to a conical expanded shape, and may include web-like struts connected between axially-extending posts. A system and method for deployment includes an integrated handle shaft and balloon catheter. A valve holder is stored with the heart valve and the handle shaft easily attaches thereto to improve valve preparation steps. 1. A system for delivering a prosthetic heart valve , comprising:a heart valve including a prosthetic valve with an expandable frame having a contracted state for delivery to an implant position and an expanded state;a valve holder attached to the heart valve and having a through passage;a balloon catheter having a balloon, the balloon catheter and a proximal end of the balloon being fixable with respect to the valve holder with the balloon passing through the through passage of the valve holder to a position within the expandable frame, the balloon catheter having a proximal end defining a lumen in which is housed a balloon extension spring and a spring compression pin, wherein the spring compression pin is fixed to a balloon extension wire that extends distally through the balloon catheter and is attached to a distal tip of the balloon, wherein the balloon is configured to axially foreshorten when inflated such that the distal tip is displaced proximally with respect to the proximal end and the balloon extension wire and spring compression pin are also displaced proximally to compress the balloon extension ...

DEVICE WITH TENSIONERS

This disclosure provides for a medical device to be implanted in the vasculature and a method for treatment in the vasculature. The device has an outer layer of a first material and an inner layer of a second material attached to the outer layer. The inner layer further has a plurality of elastomeric tensioners. If the device experiences relaxation, resulting in a decreased radial force against the vessel wall, the elastomeric tensioners may provide a contraction force to the inner layer and the outer layer, resulting in a maintained radial force on the vessel wall. 1. A method of deploying a medical device in a body vessel having a vessel wall , the method comprising: an outer layer comprising a first material and a plurality of outer cells arranged in outer circumferential rows, each outer cell having an outer perimeter comprising a first outer cell edge attached to a second outer cell edge at a distal outer cell end, defining a distal outer angle, and a third outer cell edge attached to a fourth outer cell edge at a proximal outer cell end, defining a proximal outer angle, the distal outer angle being distal the proximal outer angle along the longitudinal axis;', 'an inner layer comprising a second material being elastomeric and a plurality of inner cells arranged in inner circumferential rows, each inner cell having an inner perimeter comprising a first inner cell edge attached to a second inner cell edge at a distal inner cell end, defining a distal inner angle, and a third inner cell edge attached to a fourth inner cell edge at a proximal inner cell end, defining a proximal inner angle, the distal inner angle being distal the proximal inner angle along the longitudinal axis, wherein at least one outer perimeter is attached to at least one inner perimeter, the outer and inner layers defining a tubular body having a proximal end extending to a distal end and a lumen formed therethrough; and', 'a plurality of tensioners having an extended length and a contracted ...

Apparatus and methods for in situ embolic protection

The present invention provides apparatus and methods for treating a vascular condition by restoring patency to a vessel while reducing the likelihood that emboli become dislodged into the bloodstream. In a first embodiment, the apparatus comprises a graft having proximal and distal regions, a first support member attached to the distal region of the graft, and a second support member attached to the proximal region of the graft. The first and second support members may comprise first and second stents, respectively. The first stent is deployed distal to a vascular condition, and the second stent is deployed proximal to a vascular condition, such that the graft spans the length of the vascular condition to entrap emboli during treatment of the vascular condition. In an alternative embodiment, the first stent is adapted to be deployed within a vessel at a location distal to the vascular condition, and the graft is adapted to be everted to form a pocket adapted to entrap emboli dislodged during treatment of the vascular condition. The second stent then may be subsequently deployed proximal to the vascular condition, such that emboli trapped within the graft pocket are effectively sealed off from the bloodstream.

Stent valve and stent graft for percutaneous surgery

A star-shaped stent and replacement valve or replacement graft for use in repairing a damaged cardiac valve includes two to eight star-shaped members interconnected into a "chain". Once this "chain" has been created through interconnection of the star-shaped members, a central opening through all of the interconnected star-shaped members receives a replacement aortic valve tri-cuspid made of any suitable flexible and bio-compatible material. A catheter delivery system is used to deliver the stent with the aortic valve tri-cuspid to the desired site. The star-shaped stents are made by using a laser to cut out a plurality of flat star-shaped members with a plurality of outwardly and inwardly directed points. The outwardly directed points are bent so that they face away from a plane defined by the inwardly directed points and then a series of such stents are fastened together in a chain.

Stent valve and stent graft

A star-shaped stent and replacement valve or replacement graft for use in repairing damaged vascular organs: Two to eight star-shaped members are interconnected into a "chain". Once this "chain" has been created through interconnection of the star-shaped members, a central opening through all of the interconnected star-shaped members receives a graft made of any suitable flexible and bio-compatible material. A catheter delivery system is used to deliver the stent with the graft to the desired site. The star-shaped stents are made by using a laser to cut out a plurality of flat star-shaped members with a plurality of outwardly and inwardly directed points. The outwardly directed points are bent so that they face away from a plane defined by the inwardly directed points and then a series of such stents are fastened together in a chain.

Stent, stent graft and stent valve

A star-shaped stent and replacement valve or replacement graft for use in repairing damaged vascular organs: Two to eight star-shaped members are interconnected into a “chain”. Once this “chain” has been created through interconnection of the star-shaped members, a central opening through all of the interconnected star-shaped members receives a graft made of any suitable flexible and bio-compatible material. A catheter delivery system is used to deliver the stent with the graft to the desired site. The star-shaped stents are made by using a laser to cut out a plurality of flat star-shaped members with a plurality of outwardly and inwardly directed points. The outwardly directed points are bent so that they face away from a plane defined by the inwardly directed points and then a series of such stents are fastened together in a chain.

Prosthetic valve for transluminal delivery

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Devices, systems, and methods for treatment of duct occlusion

Stents comprising a first region and a second region are provided, where at least the second region comprises one or more phase transforming cellular materials configured to move the outlet between an open configuration and a closed configuration in response to certain triggers. Such stents can also comprise one or more analog for a shape memory alloy (ASMA) unit cells on an inner surface of the first region such that, in response to resistive forces, the ASMA unit cells exert controllable motion to clear the stent. Methods of treatment of cancer, jaundice, and other diseases are also provided.

支架植入物近端自定心输送系统和方法

在弯曲腔内定心植入假体的方法包括将假体装入输送鞘，在患者体内向弯曲腔推进鞘，至少将假体的近端安放在弯曲腔内，将假体的近端和/或鞘的远端在弯曲腔内对正中心。在推进的第一步，将载有内鞘的外导管推进到接近弯曲腔的位置，在推进的第二步，将载有假体的内鞘推进到弯曲腔内，至少将近端安置在弯曲腔内，而外导管基本上保持在原位。对正中心以后，假体的近端在弯曲腔内对中安放。

整合的混合心脏瓣膜

公开了假体心脏瓣膜及其使用方法，所述假体心脏瓣膜被配置以替代天然心脏瓣膜并且具有支撑框架，所述支撑框架被配置以再塑形为扩张形状以便在其中接收和/或支撑可扩张的假体心脏瓣膜。所述假体心脏瓣膜可以被配置以在最初被植入以替代天然瓣膜(或其他假体心脏瓣膜)时具有总体上刚性和/或抵抗扩张的构型，而在经受外向力如扩张球囊或其他机械扩张器提供的外向力时呈现总体上扩张的形式。流入支架框架可扩张以将瓣膜锚定到位，并且可以具有流出端，所述流出端可皱缩到有限程度以便进行递送并且可在植入后扩张以促进瓣中瓣(ViV)手术。该混合心脏瓣膜消除了早前的结构带，这既减少了制造时间又促进了ViV手术。

介入式瓣架以及主动脉瓣膜

本发明提供了介入式瓣架以及主动脉瓣膜，其中，介入式瓣架包括：限定框架管腔的瓣架，瓣架包括连接上游端口和下游端口的直杆以及连接在直杆之间的斜杆；沿上游端口至下游端口的方向依次形成上游段、中游段以及下游段，当瓣架自压缩状态扩展到膨胀状态时，位于中游段的斜杆向瓣架周向提供的扩展应变大于位于上游段和/或下游段的斜杆向瓣架周向提供的扩展应变，以补偿中游段的周向扩展速率与上游段和/或下游段的周向扩展速率的速率差。本发明能够通过有效接受中游段斜杆传递过来的应力，减少中游段斜杆应力集中，从而使中游段斜杆更易受力扩张，达到两端斜杆的扩张速率，因而可以减小或缓解瓣架扩展时两端外扩形成类似狗骨头结构的不良效应。

Dynamic and adjustable support devices

The present invention relates generally to dynamic and/or adjustable support devices, methods of providing dynamic and/or adjustable support to target tissues, and kits comprising these devices. These devices may have particular utility in providing support to the urethra. The dynamic support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one expandable member capable of assuming an unexpanded configuration and an expanded configuration. The adjustable support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one shape-changing portion that is capable of assuming first and second configurations, each with different shapes. Additionally, the dynamic support devices may comprise features of the adjustable support devices, and vice versa.

Apparatus and methods for in situ embolic protection

The present invention provides apparatus and methods for treating a vascular condition by restoring patency to a vessel while reducing the likelihood that emboli become dislodged into the bloodstream. In a first embodiment, the apparatus comprises a graft having proximal and distal regions, a first support member attached to the distal region of the graft, and a second support member attached to the proximal region of the graft. The first and second support members may comprise first and second stents, respectively. The first stent is deployed distal to a vascular condition, and the second stent is deployed proximal to a vascular condition, such that the graft spans the length of the vascular condition to entrap emboli during treatment of the vascular condition. In an alternative embodiment, the graft is adapted to be everted to form a pocket adapted to entrap emboli dislodged during treatment of the vascular condition.

Stent with self-expanding end sections

The present invention is a hybrid stent that is defined as having a central section that is balloon expandable and end sections that are self-expanding. The entire stent is mounted on a balloon of a balloon angioplasty catheter. One way to retain the self-expanding portion of the stent onto a balloon onto which it has been nested is to place a cylindrical elastomer tube around each of the self-expanding end sections of the stent. Another way to retain the hybrid stent onto a stent delivery system is to use a conventional sheath that is pulled back to initiate stent deployment

Stent with self-expanding end sections

The present invention is a hybrid stent that is defined as having a central section that is balloon expandable and end sections that are self-expanding. The entire stent is mounted on a balloon of a balloon angioplasty catheter. One way to retain the self-expanding portion of the stent onto a balloon onto which it has been nested is to place a cylindrical elastomer tube around each of the self-expanding end sections of the stent. Another way to retain the hybrid stent onto a stent delivery system is to use a conventional sheath that is pulled back to initiate stent deployment

Method of forming a stent pattern on a tube

Methods of fabricating an implantable medical device from a tube or a sheet in an expanded or stretched state, respectively, are disclosed herein. The implantable medical device may be an endoprosthesis such as a stent. In one embodiment, the method may include radially expanding a tube about a cylindrical axis of the tube from a first diameter to a second diameter. The method may further include forming a pattern on at least a portion of the expanded tube. Additional embodiments may include forming a stent pattern on a stretched sheet from which a stent may be formed. In addition, a stent pattern may be formed on a tube that is formed from a stretched sheet.

Prosthetic valve for transluminal delivery

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Prosthetic valve for transluminal delivery

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia.

Prosthetic valve support structure

The present invention is directed to prostheses (1200) including a support structure having a proximal end and a distal end, and a motion limiting member (1242) attached to the distal end of the support structure, wherein the motion limiting member is configured to restrict radial expansion of the distal end of the support structure. Methods for delivering the prosthesis are also provided.

Replacement heart valve

A replacement heart valve assembly has a stent frame and a replacement valve. The replacement valve has a plurality of leaflets and a valve frame. The leaflets are attached to the valve frame. Further, the assembly has a plurality of suspension struts attached to the stent frame and the valve frame. The valve frame is suspended within the stent frame via the suspension struts. In some embodiments, the assembly further has a sealing member attached to the stent frame to prevent leakage around the replacement heart valve assembly.

Prosthetic valve for transluminal delivery

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Transcatheter heart valves

A prosthetic heart valve comprises a biological tissue valve and a collapsible and expandable support frame having a longitudinal axis. The frame comprises an outflow circumferential structure defining an outflow end of the frame and consisting essentially of a single row of diamond-shaded expandable cells. The frame also comprises three V-shaped structures spaced apart from the outflow circumferential structure and three struts longitudinally aligned with the longitudinal axis of the frame. The three struts are configured to facilitate mounting the biological tissue valve to the frame and interconnect the outflow circumferential structure to the three V-shaped structures. The frame also includes three undulating structures, each of the three undulating structures interconnecting respective adjacent V-shaped structures of the three V-shaped structures. The prosthetic heart valve is configured to be collapsed for introduction into a patient using a catheter and to be expanded for deployment at an implantation site.

Prosthetic valve for transluminal delivery

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. If desired, one or more anchor may be used. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable to contact the anatomical annulus of the native valve when the assembly is properly positioned. The anchor engages the lumen wall when expanded and prevents substantial migration of the valve assembly when positioned in place. The prosthetic valve assembly is compressible about a catheter, and restrained from expanding by an outer sheath. The catheter may be inserted inside a lumen within the body, such as the femoral artery, and delivered to a desired location, such as the heart. When the outer sheath is retracted, the prosthetic valve assembly expands to an expanded position such that the valve and valve support expand within the deficient native valve, and the anchor engages the lumen wall.

Transcatheter heart valves

A prosthetic heart valve comprises a biological tissue valve and a collapsible and expandable support frame comprising a longitudinal axis. The frame comprises an outflow circumferential structure defining an outflow end of the frame and defining a similar row of expandable cells, and a circumferential undulating strut structure spaced apart from the outflow circumferential structure. The frame also comprises three struts longitudinally aligned with the longitudinal axis, configured to facilitate mounting the biological tissue valve to the frame, and interconnecting the outflow circumferential structure to the circumferential undulating structure. Each strut comprises a first end terminating at a respective junction between two adjacent expandable cells of the outflow circumferential structure, and a second end terminating at the circumferential undulating strut structure. The prosthetic heart valve is configured to be collapsed for introduction into a patient using a catheter and to be expanded for deployment at an implantation site.

Methods for transluminal delivery of prosthetic valves

A prosthetic valve assembly for use in replacing a deficient native valve comprises a replacement valve supported on an expandable valve support. The valve support, which entirely supports the valve annulus, valve leaflets, and valve commissure points, is configured to be collapsible for transluminal delivery and expandable contact the anatomical annulus of the native valve when the assembly is properly positioned. Portions of the valve support may expand to a preset diameter to maintain coaptivity of the replacement valve and to prevent occlusion of the coronary ostia.

Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements

A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements.

Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements

A method for endovascularly replacing a patient's heart valve including the following steps: endovascularly delivering an anchor and a replacement valve supported within the anchor to a vicinity of the heart valve in a collapsed delivery configuration, the anchor having grasping elements adapted to grasp tissue in a vicinity of the heart valve; expanding the anchor, thereby rotating the grasping elements; and grasping the tissue with the rotating grasping elements.

Replacement heart valve

一种置换心脏瓣膜组件具有支架框架和置换瓣膜。所述置换瓣膜具有多个小叶和瓣膜框架。所述小叶被附接至所述瓣膜框架。进一步地，所述组件具有多个被附接至所述支架框架和所述瓣膜框架的悬挂支杆。所述瓣膜框架经所述悬挂支杆悬挂在所述支架框架内。在一些实施例中，所述组件还具有被附接至所述支架框架以防在所述置换心脏瓣膜组件周围发生泄露的密封构件。

Methods for replacing a native heart valve and aorta with a prosthetic heart valve and conduit

A medical device includes an expandable conduit, a prosthetic heart valve and a delivery device, including a balloon catheter. The expandable conduit may include one or more inner or outer sleeves supported by a frame or stent. The sleeve(s) may be a bioprosthetic tissue wrapped, molded or sewn about the frame or stent. Coupled to an end of the expandable conduit is the prosthetic heart valve. The conduit and heart valve may be crimped on the balloon catheter for percutaneous deployment. The frame may be constructed of a balloon-expandable material for the conduit portion and a self-expandable material for the prosthetic heart valve portion. The prosthetic heart valve is anchored at the native heart valve and then the conduit to be expanded into place to protect the aorta. The self-expanding prosthetic heart valve avoids the need for balloon mounting. This provides for a smaller diameter and easier delivery.

Dynamic and adjustable support devices

The present invention relates generally to dynamic and/or adjustable support devices, methods of providing dynamic and/or adjustable support to target tissues, and kits comprising these devices. These devices may have particular utility in providing support to the urethra. The dynamic support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one expandable member capable of assuming an unexpanded configuration and an expanded configuration. The adjustable support devices generally comprise at least one attachment member for attachment to bodily tissue, and at least one shape-changing portion that is capable of assuming first and second configurations, each with different shapes. Additionally, the dynamic support devices may comprise features of the adjustable support devices, and vice versa.

Folding valve prosthesis

Una prótesis de válvula plegable (1) que incluye una armadura (2) y un conjunto de valvas de válvula protésica (3a, 3b, 3c) soportadas por la armadura (2), siendo la armadura (2) expandible desde un estado contraído a un estado expandido para el anclaje en un anillo de un sitio de la válvula natural, en el que la armadura (2) incluye: - una porción intra-anular tubular (2a) que define un lumen de flujo sanguíneo que tiene un lado de flujo de entrada y un lado de flujo de salida, soportando (202, 204, 206) la porción intra-anular tubular (2a) el conjunto de valvas de válvula protésica (3a, 3b, 3c) en el lumen de flujo sanguíneo y que está provista de formaciones hacia al exterior (200) para su acoplamiento con el sitio de la válvula natural, y - al menos una porción extra-anular (2b, 2c) unida a la porción intra-anular (2a), incluyendo la al menos una porción extra-anular una porción sobre-anular (2b) para extenderse a modo de collar sobre el anillo del sitio válvula natural en el lado de flujo de entrada del lumen de flujo de sangre, estando la prótesis caracterizada porque la porción intra-anular (2a) y la por lo menos una porción extra-anular (2b) son piezas separadas que tienen un elemento de acoplamiento recíproco (2000) entre las mismas. A collapsible valve prosthesis (1) that includes an armature (2) and a set of prosthetic valve leaflets (3a, 3b, 3c) supported by the armature (2), the armature (2) being expandable from a contracted state to an expanded state for anchoring in a ring of a natural valve site, in which the armature (2) includes: - a tubular intra-annular portion (2a) defining a blood flow lumen that has a flow side inlet and one outlet flow side, supporting (202, 204, 206) the tubular intra-annular portion (2a) the set of prosthetic valve leaflets (3a, 3b, 3c) in the blood flow lumen and which is provided with outward formations (200) for coupling with the site of the natural valve, and - at least one extra-annular portion (2b, 2c) attached to ...

Apparatus and methods for implanting a replacement heart valve

Systems and methods for docking a heart valve prosthesis. A system includes a helical anchor (30) formed as multiple coils (32) adapted to support a heart valve prosthesis (10) with coil portions (32) positioned above and below the heart valve annulus (12). A seal (50) is coupled with the helical anchor (30) and includes portions extending between adjacent coils (32) for preventing blood leakage through the helical anchor (30) and past the heart valve prosthesis (10). An expansible helical anchor (30) is formed as multiple coils (32) adapted to support a heart valve prosthesis (10). At least one of the coils (32) is normally being at a first diameter, and is expandable to a second, larger diameter upon application of radial outward force from within the helical anchor (30).

Prosthetic heart valve docking assembly

In a representative embodiment, an implantable assembly for a native heart valve comprises a prosthetic heart valve and first and second inflatable bodies. The prosthetic heart valve can comprise a frame and prosthetic leaflets. The first inflatable body can comprise first and second end portions, wherein the first end portion is configured to be secured to tissue of the native heart valve at a first location, and the second end portion is configured to engage an outer surface of the prosthetic valve. The second inflatable body can comprise third and fourth end portions, wherein the third end portion is configured to be secured to tissue of the native heart valve at a second location, and the fourth end portion is configured to engage the outer surface of the prosthetic valve. The first and second inflatable bodies anchor the prosthetic valve within the annulus of the native heart valve.

Prosthetic Valve and delivery tool therefor