IN-SITU FORMED STENT

A delivery system for forming a stent in-situ may comprise an elongate shaft having a proximal end and a distal end and a lumen extending from the proximal end towards the distal end of the elongate shaft. A plurality of apertures may be positioned adjacent to a distal end region of the elongate shaft. The plurality of apertures may extend from an outer surface to an inner surface of the elongate shaft and be in fluid communication with the lumen. A port may be affixed to the proximal end of the elongate shaft and in fluid communication with the lumen. 1. A delivery system for forming a stent in-situ , the system comprising:an elongate shaft having a proximal end and a distal end;a lumen extending from the proximal end towards the distal end of the elongate shaft;a plurality of apertures adjacent a distal end region of the elongate shaft, the plurality of apertures extending from an outer surface to an inner surface of the elongate shaft and in fluid communication with the lumen; anda port affixed to the proximal end of the elongate shaft and in fluid communication with the lumen.2. The delivery system of claim 1 , wherein the outer surface of the elongate shaft comprises a plurality of radially extending ridges and a plurality of valleys extending along a length of the elongate shaft.3. The delivery system of claim 2 , wherein the plurality apertures are disposed within at least one valley of the plurality of valleys.4. The delivery system of claim 2 , wherein the plurality of apertures comprises at least one aperture disposed in each valley of the plurality of valleys.5. The delivery system of claim 2 , wherein the plurality of apertures comprises a two or more apertures disposed in each valley of the plurality of valleys.6. The delivery system of claim 5 , wherein the two or more apertures are arranged in a linear array.7. The delivery system of claim 1 , wherein the plurality of apertures extend along a length of the elongate shaft corresponding to a length of a ...

STENT DELIVERY SYSTEM

Stent delivery device including an inner member having a distal tip, a stent support member, and a stent disposed over a stent receiving region of the stent support member. An elongated outer sheath is slidably disposed over the inner member and the stent. The stent delivery device includes a distal junction removably coupling the distal end of the outer sheath to the distal tip, where the distal junction is actuatable to decouple the outer sheath from the distal tip. The stent delivery device includes a proximal junction removably coupling a distal portion of the outer sheath to a proximal portion of the outer sheath, where the proximal junction is actuatable to decouple the distal portion of the outer sheath from the proximal portion of the outer sheath. The distal and proximal junctions may be separately actuatable by rotating the inner member relative to the proximal portion of the outer sheath. 1. A stent delivery system comprising:an elongated inner member extending between a distal tip and a proximal end;a stent support member disposed over the inner member and defining a stent receiving region, the inner member slidable within the stent support member;at least one stent surrounding the stent receiving region of the stent support member, the stent having a collapsed configuration and an expanded configuration;an elongated outer sheath slidably disposed over the inner member, the outer sheath extending between a distal end and a proximal end, the outer sheath including a proximal portion and a distal portion located distal of the proximal portion, the distal portion of the outer sheath surrounding the stent to restrain the stent in the collapsed configuration;a proximal junction detachably coupling the distal portion of the outer sheath to the proximal portion of the outer sheath, the proximal junction being actuatable to selectively uncouple the distal portion of the outer sheath from the proximal portion of the outer sheath; anda distal junction detachably ...

STENTS, SYSTEMS, AND METHODS FOR GASTROINTESTINAL TRACT TREATMENT

The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section. 1. A stent , comprising: a flared section;', 'a medial section extending from the flared section, wherein a diameter of the flared section is greater than a diameter of the medial section; and, 'a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends, the tubular scaffold comprisinga liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.2. The stent of claim 1 , wherein the liner is spaced apart from a medial anchoring region of the medial section to promote tissue ingrowth with the medial section.3. The stent of claim 2 , wherein the medial anchoring region is provided at an expanded portion of the medial section claim 2 , and wherein the expanded portion has a third diameter greater than the diameter of the medial section.4. The stent of claim 3 , wherein the liner is spaced from the expanded portion to promote tissue ingrowth with the expanded portion.5. The stent of claim 1 , wherein the anchoring region is located along a sloped portion of the flared section claim 1 , and wherein the sloped portion extends away from a central longitudinal axis extending through the lumen.6. ...

POLYPECTOMY SNARE DEVICES

Polypectomy devices and methods for making and using polypectomy devices are disclosed. An example polypectomy device may include an elongate sheath having a proximal end and a distal end. A handle assembly may be coupled to the proximal end. The handle assembly may include a first actuator and a second actuator. A first shaft may extend through the sheath and may be coupled to the first actuator. An end effector may be coupled to the first shaft. A second shaft may extend through the sheath and may be coupled to the second actuator. A retention member may be coupled to the second shaft. The first actuator may be designed to shift the end effector between a housed configuration and a deployed configuration. The second actuator may be designed to shift the retention member between a retracted configuration and a holding configuration. 1. A polypectomy device , comprising:an elongate sheath having a proximal end and a distal end;a handle assembly coupled to the proximal end, the handle assembly including a first actuator and a second actuator;a first shaft extending through the sheath and coupled to the first actuator;an end effector coupled to the first shaft;a second shaft extending through the sheath and coupled to the second actuator;a retention member coupled to the second shaft;wherein the first actuator is designed to shift the end effector between a housed configuration and a deployed configuration; andwherein the second actuator is designed to shift the retention member between a retracted configuration and a holding configuration.2. The polypectomy device of claim 1 , wherein the first actuator and the second actuator are independently controllable.3. The polypectomy device of claim 1 , wherein the end effector includes a snare loop.4. The polypectomy device of claim 1 , wherein the retention member includes a retention barb.5. The polypectomy device of claim 1 , wherein the retention member includes a spike.6. The polypectomy device of claim 1 , wherein the ...

ADJUSTABLE MANDREL FOR FORMING STENT WITH ANTI-MIGRATION FEATURES

A mandrel for forming a stent with a tapered profile and one or more anti-migration features includes a first stent shaping segment having a first diameter, a second stent shaping segment having a second diameter less than the first diameter and a tapered segment disposed therebetween. A third stent shaping segment is releasably securable to the second stent shaping segment and has a third diameter greater than the second diameter. One or more movable pins are outwardly extendable from corresponding apertures formed within the tapered segment. An actuation element is engagable with the first stent shaping segment and includes a tapered surface configured to engage the one or more movable pins and support the one or more movable pins extended from the corresponding apertures. 1. A mandrel comprising: a bore extending within the mandrel body; and', 'one or more apertures radially disposed about the mandrel body;, 'a mandrel body includingone or more movable pins outwardly extendable from the one or more apertures; andan actuation element engagable with the bore extending within the mandrel body and including a tapered surface configured to engage the one or more movable pins, the actuation element being actuatable relative to the mandrel body such that the tapered surface supports the one or more movable pins extended from the one or more apertures to form an anti-migratory stent.2. The mandrel of claim 1 , wherein the mandrel body comprises:a first stent shaping segment having a first diameter;a second stent shaping segment having a second diameter less than the first diameter; anda tapered segment disposed between the first stent shaping segment and the second stent shaping segment.3. The mandrel of claim 2 , further comprising a third stent shaping segment releasably securable to the second stent shaping segment claim 2 , the third stent shaping segment having a third diameter greater than the second diameter.4. The mandrel of claim 2 , wherein the one or more ...

STENT DELIVERY SYSTEM

An example stent delivery system is disclosed. The example stent delivery system includes an inner shaft having a proximal portion, a distal portion and at least one lumen extending therein. The inner shaft further includes a stent receiving region disposed along the distal portion. The stent delivery system further includes a stent disposed along the stent receiving region. Additionally, the inner member includes a plurality of apertures disposed along at least a portion of the stent receiving region and the plurality of apertures are configured to permit fluid to flow therethrough and expand the stent. 1. A stent delivery system , comprising:an inner shaft having a proximal portion, a distal portion and at least one lumen extending therein, the inner shaft further including a stent receiving region disposed along the distal portion;a stent disposed along the stent receiving region;wherein the inner member includes a plurality of apertures disposed along at least a portion of the stent receiving region;wherein the plurality of apertures are configured to permit fluid to flow therethrough against an inner surface of the stent to assist expansion of the stent.2. The stent delivery system of claim 1 , further comprising a deployment sheath disposed about the inner shaft.3. The stent delivery system of claim 2 , wherein the stent is disposed between the deployment sheath and the inner shaft.4. The stent delivery system of claim 1 , wherein each of the plurality of apertures is in fluid communication with the at least one lumen of the inner shaft.5. The stent delivery system of claim 4 , wherein the at least one lumen extending within the inner shaft is configured to permit a guidewire to extend therethrough.6. The stent delivery system of claim 1 , wherein the inner shaft includes a plurality of lumens extending therein claim 1 , and wherein at least one of the plurality of lumens is in fluid communication with each of the plurality of apertures.7. The stent delivery ...

STENT RETRIEVAL SYSTEM

A braided stent having a plurality of retrieval and/or repositioning levers includes a stent body formed of a plurality of wires interbraided in a braided pattern. The repositioning and/or retrieval levers have a loop portion extending radially away from the stent body and first and second legs extending along the stent body. The levers are configured to be actuated radially inward toward the central longitudinal axis of the stent by a radially inwardly directed force to radially collapse the stent. 1. A stent comprising:a tubular body formed of a plurality of interwoven wires, the tubular body having a lumen extending therethrough from a first open end of the tubular body to a second open end of the tubular body, the tubular body having a length measured from the first open end to the second open end and a longitudinal axis extending therebetween; anda plurality of repositioning and/or retrieval levers formed as separate elements from the plurality of interwoven wires, the plurality of repositioning and/or retrieval levers attached to the tubular body at a plurality of discrete points spaced apart circumferentially around the first open end, the plurality of repositioning and/or retrieval levers including a loop portion extending longitudinally beyond and radially outward from the first open end of the tubular body, each repositioning and/or retrieval lever having first and second legs extending from the loop portion and along a portion of the tubular body toward the second open end, wherein the repositioning and/or retrieval levers are configured to translate a radially inward squeezing force applied to the repositioning and/or retrieval levers at a location longitudinally beyond the first open end to a radially inward contracting force along the first and second legs extending along the tubular body.2. The stent of claim 1 , wherein the plurality of repositioning and/or retrieval levers includes at least three repositioning and/or retrieval levers.3. The stent of ...

METHODS AND DEVICES FOR TISSUE BIOPSY

Medical devices and methods are disclosed in the present application. In one illustrative example a tissue removal device may comprise an elongate shaft defining a lumen and having a proximal end and a distal end, wherein a proximal portion of the elongate shaft has a first diameter and a distal portion of the elongate shaft has a second diameter, and wherein the first diameter is less than the second diameter and an elongate member disposed at least partially within the elongate shaft, the elongate member having a proximal end and a distal end, the distal end of the elongate member comprising a cap. In some further embodiments, the elongate member may be axially translatable between a proximal position and a distal position, and the cap may form a closed receptacle with the distal portion of the elongate shaft when the elongate member is in the proximal position. 1. A tissue removal device comprising:an elongate shaft defining a lumen and having a proximal end and a distal end, wherein a proximal portion of the elongate shaft has a first diameter and a distal portion of the elongate shaft has a second diameter, and wherein the first diameter is less than the second diameter; andan elongate member disposed at least partially within the elongate shaft, the elongate member having a proximal end and a distal end, the distal end of the elongate member comprising a cap;wherein the elongate member is axially translatable between a proximal position and a distal position, andwherein the cap forms a closed receptacle with the distal portion of the elongate shaft when the elongate member is in the proximal position.2. The device of claim 1 , wherein the distal portion of the elongate shaft is removable from the proximal portion of the elongate shaft.3. The device of claim 1 , wherein the cap is removable from the elongate member.4. The device of claim 1 , wherein the cap extends distally beyond the distal end of the elongate shaft.5. The device of claim 1 , wherein a ...

STENT INCLUDING ANTI-MIGRATION CAPABILITIES

An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold including first and second regions, each of the first and second regions include a plurality of interstices located therein. The medical device also includes a covering spanning each of the plurality of interstices of the first region. The second region is free of the covering. A biodegradable gripping material is disposed on an outer surface of the covering. Further, the expandable scaffold is configured to shift from a collapsed state to an expanded state and the second region is configured to contact an inner surface of the body lumen in the expanded state. Additionally, the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second region is secured to the inner surface of the body lumen.

IMPLANTABLE MEDICAL DEVICE WITH BONDING REGION

Medical devices and methods for making and using a medical device are disclosed. An example medical device may include an implantable endoprosthesis. The implantable endoprosthesis may include a cylindrical body having a proximal end, a distal end, and an axial bonding region extending between the proximal end and the distal end. The cylindrical body may include one or more winding filaments and a plurality of discrete axial bonds disposed along the axial bonding region. The discrete axial bonds may secure together edge regions of the one or more winding filaments. 1. An implantable endoprosthesis , comprising:a cylindrical body having a proximal end, a distal end, and an axial bonding region extending between the proximal end and the distal end;wherein the cylindrical body includes one or more winding filaments; anda plurality of discrete axial bonds disposed along the axial bonding region, the discrete axial bonds securing together edge regions of the one or more winding filaments.2. The endoprosthesis of claim 1 , wherein the one or more winding filaments includes a braided portion claim 1 , a knitted portion claim 1 , or both.3. The endoprosthesis of claim 2 , wherein the one or more winding filaments includes a braided portion and a knitted portion claim 2 , wherein the braided portion is interwoven with the knitted portion.4. The endoprosthesis of claim 1 , wherein the winding filaments includes a first filament having a first radial compression strength and a second filament having a second radial compression strength different from the first radial compression strength.5. The endoprosthesis of claim 1 , wherein the discrete axial bonds include a weld.6. The endoprosthesis of claim 1 , wherein the cylindrical body further comprises a bifurcated portion.7. The endoprosthesis of claim 6 , wherein the cylindrical body includes a second axial bonding region.8. An implantable endoprosthesis claim 6 , comprising:a tubular scaffold including a proximal end, a distal ...

STENT INCLUDING ANTI-MIGRATION CAPABILITIES

An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold including first and second regions, each of the first and second regions include a plurality of interstices located therein. The medical device also includes a covering spanning each of the plurality of interstices of the first region. The second region is free of the covering. A biodegradable gripping material is disposed on an outer surface of the covering. Further, the expandable scaffold is configured to shift from a collapsed state to an expanded state and the second region is configured to contact an inner surface of the body lumen in the expanded state. Additionally, the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second region is secured to the inner surface of the body lumen. 1. A medical device for treating a body lumen , comprising:an expandable scaffold including a first region and a second region, each of the first and second regions including a plurality of interstices located therein;a covering spanning each of the plurality of interstices of the first region, and wherein the second region is free of the covering; anda gripping material disposed on an outer surface of the covering, wherein the gripping material is biodegradable;wherein the expandable scaffold is configured to shift from a collapsed state to an expanded state, and wherein the second region is configured to contact an inner surface of the body lumen in the expanded state;wherein the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second region is secured to the inner surface of the body lumen via tissue ingrowth into the interstices of the second region.2. The medical device of claim 1 , wherein the tissue ingrowth into the interstices of the second region is due to a hyperplasic tissue response.3. ...

STENT ANCHORING SYSTEM

An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member may include at least one barb attached thereto. The barb may be configured to be tucked under a filament of the stent during delivery of the stent and protrude radially from the stent, when the stent is deployed. 1. A stent , the stent comprising:an elongated tubular member comprising at least one filament wound to form a plurality of cells, the elongated tubular member configured to move between a collapsed configuration and an expanded configuration, wherein in the collapsed configuration the plurality of cells have a first profile and in the expanded configuration the plurality of cells have a second profile different from the first profile; andat least one barb attached to the at least one filament at one end of the barb and extending towards a free end;wherein the free end of the at least one barb is configured to be positioned radially inward to an adjacent winding of the at least one filament when the elongated tubular member is in the collapsed configuration and to extend radially away from the elongated tubular member when the elongated tubular member is in the expanded configuration.2. The stent of claim 1 , wherein the first profile of the plurality of cells has a major dimension extending along a longitudinal axis of the elongated tubular member.3. The stent of claim 1 , wherein the second profile of the plurality of cells has a major dimension extending along a circumference of the elongated tubular member.4. The stent of claim 1 , wherein the at least one barb comprises a wire.5. The stent of claim 4 , wherein the at least one barb is attached to the at least one filament at a terminal end of the at least one barb.6. The stent of claim 4 , wherein the at least one barb is attached to the at least one filament along a length of the at least one barb claim 4 , the length ...

DEPLOYABLE SLEEVES AND RELATED METHODS

A medical device may include a tubular sleeve configured for implantation in a body lumen, the sleeve having a first configuration with a first rigidity and a second configuration with a second rigidity greater than the first rigidity, the sleeve including: a flexible membrane defining an interior lumen; and a channel extending along the membrane. 1. A medical device , comprising: a flexible membrane defining an interior lumen; and', 'a channel extending along the membrane., 'a tubular sleeve configured for implantation in a body lumen, the sleeve having a first configuration with a first rigidity and a second configuration with a second rigidity greater than the first rigidity, the sleeve including2. The medical device of claim 1 , the channel being configured to receive and retain a fluid.3. The medical device of claim 1 , wherein the membrane includes a polymer.4. The medical device of claim 1 , further comprising an anchor coupled to a proximal end of the sleeve.5. The medical device of claim 1 , wherein the channel includes a self-sealing material claim 1 , a valve claim 1 , or a cap at a proximal end.6. The medical device of claim 1 , wherein the channel is one of spiral-shaped or ring-shaped.7. The medical device of claim 1 , wherein the channel includes Nitinol.8. The medical device of claim 1 , further comprising a element secured to a distal end of the channel and extending through the channel to a proximal end of the channel claim 1 , wherein applying a proximal force to the element is configured to at least one of axially shorten or radially shorten the sleeve claim 1 , and releasing the proximal force is configured to at least one of axially lengthen or radially expand the sleeve.9. The medical device of claim 1 , wherein the channel is defined by a material of the membrane.10. A medical device claim 1 , comprising:an anchor; and a flexible membrane defining an interior lumen; and', 'a channel configured to receive and retain a fluid., 'a sleeve ...

STENT ANCHORING SYSTEM

An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member may include at least one barb attached thereto. The barb may be configured to be tucked under a filament of the stent during delivery of the stent and protrude radially from the stent, when the stent is deployed. 1. A stent , the stent comprising:an elongated tubular member comprising at least one filament interwoven to form a plurality of cells, the elongated tubular member configured to move between a collapsed configuration and an expanded configuration; andat least one barb fixed to the at least one filament, the at least one barb having a first end, a second end, and a middle region extending therebetween, wherein both the first end and the second end are fixed to the at least one filament at spaced apart positions, and the middle region is free of attachment to the elongated tubular member in the expanded configuration;wherein the middle region of the at least one barb is configured to be positioned radially inward of and under an adjacent winding of the at least one filament when the elongated tubular member is in the collapsed configuration and to extend radially away from the elongated tubular member when the elongated tubular member is in the expanded configuration.2. The stent of claim 1 , wherein the at least one barb is formed from a wire.3. The stent of claim 2 , wherein the at least one barb is triangular shaped with the middle region defining a pointed free end.4. The stent of claim 3 , wherein the wire defines two sides of the triangular shaped barb and a section of the at least one filament between the first and second ends of the at least one barb defines a third side claim 3 , with an opening extending transversely through the triangular shaped barb.5. The stent of claim 1 , wherein the spaced apart positions where the first end and the second end of the wire are fixed ...

Stent including anti-migration capabilities

An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold including first and second regions, each of the first and second regions include a plurality of interstices located therein. The medical device also includes a covering spanning each of the plurality of interstices of the first region. The second region is free of the covering. A biodegradable gripping material is disposed on an outer surface of the covering. Further, the expandable scaffold is configured to shift from a collapsed state to an expanded state and the second region is configured to contact an inner surface of the body lumen in the expanded state. Additionally, the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second region is secured to the inner surface of the body lumen.

Laser-based surgical systems and related methods

According to one aspect, a medical system may include a laser source for providing laser energy. The medical system may also include a fluid source containing a fluid for absorbing the laser energy to generate heat. The medical system may further include a medical device operatively coupled to the laser source and the fluid source. The medical device may include a shaft having a distal end, and a cap at the distal end of the shaft. The cap may include a lens and a reflector for deflecting the laser energy toward the lens. The lens may be configured to emit the laser energy from the cap toward a target.

STENT ANCHORING SYSTEM

An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member may include at least one barb attached thereto. The barb may be configured to be tucked under a filament of the stent during delivery of the stent and protrude radially from the stent, when the stent is deployed. 1. A stent , the stent comprising:an elongated tubular member comprising at least one filament interwoven to form a plurality of cells, the elongated tubular member configured to move between a collapsed configuration and an expanded configuration; andat least one barb fixed to the at least one filament, the at least one barb having a first end, a second end, and a length extending therebetween, the at least one barb fixed to the at least one filament at least along a portion of the length of the at least one barb between the first and second ends, wherein at least the first end is free of attachment to the elongated tubular member in the expanded configuration;wherein the free first end of the at least one barb is configured to be positioned radially inward of and under an adjacent winding of the at least one filament when the elongated tubular member is in the collapsed configuration and to extend radially away from the elongated tubular member when the elongated tubular member is in the expanded configuration.2. The stent of claim 1 , wherein in the collapsed configuration the plurality of cells have a first profile and in the expanded configuration the plurality of cells have a second profile different from the first profile claim 1 , wherein the first profile of the plurality of cells has a major dimension extending along a longitudinal axis of the elongated tubular member.3. The stent of claim 2 , wherein the second profile of the plurality of cells has a major dimension extending along a circumference of the elongated tubular member.4. The stent of claim 1 , wherein the at ...

Esophageal stent including an inner liner

An example medical device is disclosed as an expandable stent. The stent includes a tubular scaffold having an inner surface, an outer surface, and a lumen extending therein. The expandable stent also includes a liner disposed within the lumen of the tubular scaffold. Further, the liner is radially spaced from a medial region of the tubular scaffold to define a tissue ingrowth region along an uncovered portion of the medial region. Additionally, the liner extending along the tissue ingrowth region is configured to limit the amount of tissue ingrowth along the medial region of the scaffold.

RETRIEVABLE STENT SYSTEM

A system for treating a body lumen including a first stent configured to be positioned in a body lumen and a second stent configured to be positioned in the lumen of the first stent prior to removing the first stent from the body lumen. The first stent includes a liner disposed radially inward of the tubular scaffold of the first stent to permit tissue ingrowth within a tissue ingrowth region defined between the liner and the tubular scaffold. The retrieval stent is configured to be expanded within the previously implanted first stent to cause tissue to recede from the tissue ingrowth region to facilitate removal of the first stent from the body lumen. 1. A method of treating a body lumen , the method comprising: 'a liner disposed within the lumen of the implanted stent, wherein the liner is configured to be radially spaced from a medial region of the implanted stent to define a tissue ingrowth region along a portion of the implanted stent;', 'advancing a retrieval stent into the lumen of an implanted stent disposed along an inner surface of the body lumen, wherein a portion of tissue defining the inner surface of the body lumen has grown into the implanted stent, and wherein the implanted stent includesdeploying the retrieval stent within the lumen of the implanted stent, wherein an outer surface of the retrieval stent exerts an outward radial force along the ingrown tissue region of the implanted stent, and wherein the retrieval stent causes the ingrown tissue to recede.2. The method of claim 1 , wherein the outer surface of the retrieval stent is defined by a polymeric covering.3. The method of claim 2 , wherein the retrieval stent includes a radially expandable scaffold and the polymeric covering extends across interstices of the radially expandable scaffold.4. The method of claim 3 , wherein the radially expandable scaffold is self-expandable.5. The method of claim 4 , wherein the radially expandable scaffold includes a first end region and a second end region ...

ESOPHAGEAL STENT INCLUDING AN INNER LINER

An example medical device is disclosed as an expandable stent. The stent includes a tubular scaffold having an inner surface, an outer surface, and a lumen extending therein. The expandable stent also includes a liner disposed within the lumen of the tubular scaffold. Further, the liner is radially spaced from a medial region of the tubular scaffold to define a tissue ingrowth region along an uncovered portion of the medial region. Additionally, the liner extending along the tissue ingrowth region is configured to limit the amount of tissue ingrowth along the medial region of the scaffold. 1. An expandable medical device , comprising:a tubular scaffold, the tubular scaffold including an inner surface, an outer surface, a first end region, a second end region, a medial region positioned between the first end region and the second end region, and a lumen extending from the first end region to the second end region; anda liner disposed within the lumen of the tubular scaffold;wherein first portions of the liner are secured to and in direct contact with first regions of the inner surface of the tubular scaffold, thereby preventing tissue ingrowth, and second regions of the inner surface are not in direct contact with the liner thereby defining tissue ingrowth regions.2. The medical device of claim 1 , wherein the liner extends at least along an entirety of the medial region of the tubular scaffold.3. The medical device of claim 2 , wherein the liner extends from the first end region to the second end region of the tubular scaffold.4. The medical device of claim 1 , wherein a first end portion of the liner forms an outer layer disposed along a portion of the outer surface of the tubular scaffold along the first end region claim 1 , and a second end portion of the liner forms an outer layer disposed along a portion of the outer surface of the tubular scaffold along the second end region.54. The medical device of claim of claim 1 , wherein the liner is circumferentially ...

STENTS WITH DUAL TISSUE-WALL ANCHORING FEATURES

The present disclosure relates generally to the field of stents for body lumen drainage. In particular, the present disclosure relates to systems and methods for forming a fluid channel between tissue walls of varying thickness using a stent. 1. A stent , comprising:a stent body formed of a woven filament having a constrained configuration,the stent body having an expanded configuration with a proximal portion of the body expanded into a proximal retention member, a distal portion expanded into a distal retention member, and a cylindrical saddle region extending between the proximal and distal retention members;wherein the proximal retention member, distal retention member and cylindrical saddle region define an open interior passage configured to permit flow therethrough; andwherein the proximal retention member includes first and second flanges separated from each other by a first distance, and the distal retention member includes third and fourth flanges separated from each other by a second distance, the first distance being greater than the second distance.2. The stent of claim 1 , wherein the second and third flanges are separated by a third distance claim 1 , the third distance being greater than the first distance.3. The stent of claim 1 , wherein the first claim 1 , second claim 1 , third and fourth flanges extend perpendicular to a circumference of the stent body.4. The stent of claim 1 , wherein a diameter of the first claim 1 , second claim 1 , third and fourth flanges is larger than a diameter of the cylindrical saddle region.5. The stent of claim 1 , wherein the first and second flanges are configured to contact opposite sides of a first tissue layer claim 1 , and the third and fourth flanges are configured to contact opposite sides of a second tissue layer.6. The stent of claim 1 , further comprising a valve disposed within the open interior passage of the stent body.7. A stent claim 1 , comprising:an elongate body having a constrained configuration, ...

RETRIEVABLE STENT SYSTEM

A system for treating a body lumen including a first stent configured to be positioned in a body lumen and a second stent configured to be positioned in the lumen of the first stent prior to removing the first stent from the body lumen. The first stent includes a liner disposed radially inward of the tubular scaffold of the first stent to permit tissue ingrowth within a tissue ingrowth region defined between the liner and the tubular scaffold. The retrieval stent is configured to be expanded within the previously implanted first stent to cause tissue to recede from the tissue ingrowth region to facilitate removal of the first stent from the body lumen. 1. A system for treating a body lumen , comprising: a first tubular scaffold, the first tubular scaffold including an inner surface, an outer surface and a lumen extending therethrough; and', 'a liner disposed within the lumen of the first tubular scaffold, wherein the liner is configured to be radially spaced from the inner surface of the first tubular scaffold to permit tissue ingrowth along a portion of first tubular scaffold; and, 'a first stent including 'a second tubular scaffold and a covering disposed on the second tubular scaffold;', 'a second stent includingwherein the second stent is configured to be positioned within the first stent such that expansion of the second stent causes the tissue ingrowth to recede.2. The system of claim 1 , wherein the second tubular scaffold is configured to expand radially outward claim 1 , and wherein the radially outward expansion of the second tubular scaffold causes the tissue ingrowth to recede.3. The system of claim 1 , wherein the first stent includes an inner surface having a first profile claim 1 , and wherein the second stent includes an outer surface having a second profile claim 1 , and wherein the first profile matches the second profile.4. The system of claim 1 , wherein the second stent includes a first end region and a second end region claim 1 , and wherein ...

IMPLANTABLE MEDICAL DEVICE WITH REDUCED MIGRATION CAPABILITIES

Medical devices and methods for making and using a medical device are disclosed. An example medical device may include a stent that comprises a first covered region formed of one or more interwoven filaments and a covering. The stent may also comprise a second uncovered region adjacent the first covered region. The second uncovered region may include a knitted filament. A first end of the knitted filament may be attached to the first covered region. The knitted filament is configured to be unraveled to remove both the first covered region and the second uncovered region of the stent while the first end of the knitted stent remains attached to the first covered region. 1. A stent comprising:a first covered region formed of one or more interwoven filaments and a covering; anda second uncovered region adjacent the first covered region, wherein the second uncovered region includes a knitted filament;wherein a first end of the knitted filament is attached to the first covered region;wherein the knitted filament is configured to be unraveled to remove both the first covered region and the second uncovered region of the stent while the first end of the knitted stent remains attached to the first covered region.2. The stent of claim 1 , wherein the one or more interwoven filaments of the first covered region include a plurality of braided filaments.3. The stent of claim 1 , wherein the one or more interwoven filaments of the first covered region include a knitted filament.4. The stent of claim 3 , wherein the knitted filament of the second uncovered region and the knitted filament of the first covered region comprise a single knitted filament.5. The stent of claim 1 , wherein the first end of the knitted filament is attached to the first covered region at a first attachment point.6. The stent of claim 5 , wherein the first weld point is configured to terminate the unraveling of the knitted filament beyond the first attachment point.7. The stent of claim 1 , wherein the ...

STENT RETRIEVAL SYSTEM

A braided stent having a plurality of retrieval and/or repositioning levers includes a stent body formed of a plurality of wires interbraided in a braided pattern. The repositioning and/or retrieval levers have a loop portion extending radially away from the stent body and first and second legs extending along the stent body. The levers are configured to be actuated radially inward toward the central longitudinal axis of the stent by a radially inwardly directed force to radially collapse the stent. 1. A stent comprising:a tubular body formed of one or more interwoven wires, the tubular body having a lumen extending therethrough from a first open end of the tubular body to a second open end of the tubular body, the tubular body having a length measured from the first open end to the second open end and a longitudinal axis extending therebetween; anda plurality of repositioning and/or retrieval levers spaced apart circumferentially around the first open end and extending beyond the first open end, the repositioning and/or retrieval levers extending radially outward from the tubular body, each repositioning and/or retrieval lever having first and second legs extending along a portion of the tubular body toward the second open end, wherein the repositioning and/or retrieval levers are configured to translate a radially inward squeezing force applied to the repositioning and/or retrieval levers at a location beyond the first open end to a radially inward contracting force along the first and second legs extending along the tubular body.2. The stent of claim 1 , wherein the plurality of repositioning and/or retrieval levers are separate elements from the interwoven wires forming the tubular body.3. The stent of claim 1 , wherein the plurality of repositioning and/or retrieval levers include three levers attached to and extending beyond the first open end of the tubular body.4. The stent of claim 1 , wherein each of the plurality of repositioning and/or retrieval levers ...

DELIVERY SYSTEMS FOR DEVICES WITH UNSUPPORTED STRUCTURE

The present disclosure relates generally to the field of medical devices and medical device delivery. In particular, the present disclosure relates to medical devices and delivery systems for positioning and delivering medical devices with an unsupported structure, for example, within a distant and/or tortuous portion of body lumen. For example, a delivery system may position a supported structure of a medical device within a proximal portion of a body lumen and an unsupported structure of the medical device within a distal portion of the body lumen. Examples include delivery systems within an unsupported structure of a medical device to be delivered, wherein a number of balloons are arranged un-inflated within the unsupported, with a distal balloon removably attached to a distal portion of the unsupported structure, and the balloons are inflatable in series to deploy the unsupported structure linearly from the distal end of the delivery system. 1. A medical device delivery system , comprising:an elongate member;a medical device disposed within a distal portion of the elongate member, the medical device comprising a proximal supported structure and a distal unsupported structure;the medical device configured to move from a first position, in which the supported structure is disposed within the distal portion of the elongate member in a first configuration, and a second position in which the supported structure extends beyond a distal end of the elongate member in a second configuration;a plurality of balloons disposed within the distal portion of the elongate member and the unsupported structure; anda fluid delivery lumen extending through the elongate member, a proximal end of the fluid delivery lumen configured to fluidly connect to a fluid source and a distal end of the fluid delivery lumen in fluid communication with the plurality of balloons;wherein each balloon of the plurality of balloons is in a concertinaed configuration;wherein the unsupported structure is ...

DEVICES AND METHODS FOR MULTI-LUMEN ACCESS AND DRAINAGE

The present disclosure relates generally to the field of medical devices and establishing fluid communication between body lumens. In particular, the present disclosure relates to minimally invasive endoscopy devices and methods for body lumen access and/or drainage, and devices and methods for creating an open flow passage between two or more body lumens. 1. A medical device , comprising:an elongate tubular member having a first collapsed configuration;the elongate tubular member having a second expanded configuration with a first portion of the elongate tubular member expanded into a first retention member defining a first opening, a second portion of the elongate tubular member expanded into a second retention member defining a second opening, and a cylindrical saddle region having a circumference and longitudinal axis extending between the first and second retention members;wherein the cylindrical saddle region includes a third opening defined therein;wherein the first retention member, second retention member and cylindrical saddle region are covered apart from the first, second and third openings; andwherein the proximal retention member, distal retention member and cylindrical saddle region define an open interior passage therethrough.2. The medical device of claim 1 , wherein the first retention member includes a first flared flange structure claim 1 , and the second retention members includes a second flared flange structure.3. The medical device of claim 1 , wherein the first retention member includes a first single-wall flange structure claim 1 , and the second retention member includes a second single-wall flange structure.4. The medical device of claim 1 , wherein the first retention member includes a first double-wall flange structure claim 1 , and the second retention member includes a second double-wall flange structure.5. The medical device of claim 1 , wherein the cylindrical saddle region includes a constant outer diameter.6. The medical device of ...

Deployable sleeves and related methods

A medical device may include a tubular sleeve configured for implantation in a body lumen, the sleeve having a first configuration with a first rigidity and a second configuration with a second rigidity greater than the first rigidity, the sleeve including: a flexible membrane defining an interior lumen; and a channel extending along the membrane.

Stent delivery system

Stent delivery device including an inner member having a distal tip, a stent support member, and a stent disposed over a stent receiving region of the stent support member. An elongated outer sheath is slidably disposed over the inner member and the stent. The stent delivery device includes a distal junction removably coupling the distal end of the outer sheath to the distal tip, where the distal junction is actuatable to decouple the outer sheath from the distal tip. The stent delivery device includes a proximal junction removably coupling a distal portion of the outer sheath to a proximal portion of the outer sheath, where the proximal junction is actuatable to decouple the distal portion of the outer sheath from the proximal portion of the outer sheath. The distal and proximal junctions may be separately actuatable by rotating the inner member relative to the proximal portion of the outer sheath.

Stents with dual tissue-wall anchoring features

The present disclosure relates generally to the field of stents for body lumen drainage. In particular, the present disclosure relates to systems and methods for forming a fluid channel between tissue walls of varying thickness using a stent.

Stent delivery system

Stent delivery device including an inner member having a distal tip, a stent support member, and a stent disposed over a stent receiving region of the stent support member. An elongated outer sheath is slidably disposed over the inner member and the stent. The stent delivery device includes a distal junction removably coupling the distal end of the outer sheath to the distal tip, where the distal junction is actuatable to decouple the outer sheath from the distal tip. The stent delivery device includes a proximal junction removably coupling a distal portion of the outer sheath to a proximal portion of the outer sheath, where the proximal junction is actuatable to decouple the distal portion of the outer sheath from the proximal portion of the outer sheath. The distal and proximal junctions may be separately actuatable by rotating the inner member relative to the proximal portion of the outer sheath.

Implantable medical device with bonding region

Medical devices and methods for making and using a medical device are disclosed. An example medical device may include an implantable endoprosthesis. The implantable endoprosthesis may include a cylindrical body having a proximal end, a distal end, and an axial bonding region extending between the proximal end and the distal end. The cylindrical body may include one or more winding filaments and a plurality of discrete axial bonds disposed along the axial bonding region. The discrete axial bonds may secure together edge regions of the one or more winding filaments.

Esophageal stent including an inner liner

An example medical device is disclosed as an expandable stent. The stent includes a tubular scaffold having an inner surface, an outer surface, and a lumen extending therein. The expandable stent also includes a liner disposed within the lumen of the tubular scaffold. Further, the liner is radially spaced from a medial region of the tubular scaffold to define a tissue ingrowth region along an uncovered portion of the medial region. Additionally, the liner extending along the tissue ingrowth region is configured to limit the amount of tissue ingrowth along the medial region of the scaffold.

Stents with dual tissue-wall anchoring features

The present disclosure relates generally to the field of stents for body lumen drainage. In particular, the present disclosure relates to systems and methods for forming a fluid channel between tissue walls of varying thickness using a stent.

Stent delivery system

Stent delivery device including an inner member having a distal tip, a stent support member, and a stent disposed over a stent receiving region of the stent support member. An elongated outer sheath is slidably disposed over the inner member and the stent. The stent delivery device includes a distal junction removably coupling the distal end of the outer sheath to the distal tip, where the distal junction is actuatable to decouple the outer sheath from the distal tip. The stent delivery device includes a proximal junction removably coupling a distal portion of the outer sheath to a proximal portion of the outer sheath, where the proximal junction is actuatable to decouple the distal portion of the outer sheath from the proximal portion of the outer sheath. The distal and proximal junctions may be separately actuatable by rotating the inner member relative to the proximal portion of the outer sheath.

Stents with dual tissue-wall anchoring features

The present disclosure relates generally to the field of stents for body lumen drainage. In particular, the present disclosure relates to systems and methods for forming a fluid channel between tissue walls of varying thickness using a stent.

Delivery systems for devices with unsupported structure

The present disclosure relates generally to the field of medical devices and medical device delivery. In particular, the present disclosure relates to medical devices and delivery systems for positioning and delivering medical devices with an unsupported structure, for example, within a distant and/or tortuous portion of body lumen. For example, a delivery system may position a supported structure of a medical device within a proximal portion of a body lumen and an unsupported structure of the medical device within a distal portion of the body lumen. Examples include delivery systems within an unsupported structure of a medical device to be delivered, wherein a number of balloons are arranged un-inflated within the unsupported, with a distal balloon removably attached to a distal portion of the unsupported structure, and the balloons are inflatable in series to deploy the unsupported structure linearly from the distal end of the delivery system.

Retrievable stent system

A system for treating a body lumen including a first stent configured to be positioned in a body lumen and a second stent configured to be positioned in the lumen of the first stent prior to removing the first stent from the body lumen. The first stent includes a liner disposed radially inward of the tubular scaffold of the first stent to permit tissue ingrowth within a tissue ingrowth region defined between the liner and the tubular scaffold. The retrieval stent is configured to be expanded within the previously implanted first stent to cause tissue to recede from the tissue ingrowth region to facilitate removal of the first stent from the body lumen.

Retrievable stent system

A system for treating a body lumen including a first stent configured to be positioned in a body lumen and a second stent configured to be positioned in the lumen of the first stent prior to removing the first stent from the body lumen. The first stent includes a liner disposed radially inward of the tubular scaffold of the first stent to permit tissue ingrowth within a tissue ingrowth region defined between the liner and the tubular scaffold. The retrieval stent is configured to be expanded within the previously implanted first stent to cause tissue to recede from the tissue ingrowth region to facilitate removal of the first stent from the body lumen.

Retrievable stent system

The present invention relates to a system for treating a body lumen, comprising an implantable stent (10, 110, 210, 310, 410), including a tubular scaffold having a first flared end region (14), a second flared end region (16) and a medial region (18) extending between the first flared end region (14) and the second flared end region (16), and a liner (20, 120, 220, 320, 420) directly attached to the tubular scaffold at a first attachment point (30) and a second attachment point (32), and wherein the liner is configured to be radially spaced from an inner surface (24, 124, 224, 324) of the tubular scaffold between the first attachment point (30) and the second attachment point (32) to define a tissue ingrowth region (36) between an outer surface (38) of the liner (20, 120, 220, 320, 420) and the inner surface (24, 124, 224, 324) of the tubular scaffold, and a retrieval stent (510) configured to be positioned within a lumen of the implantable stent (10, 110, 210, 310, 410) wherein the retrieval stent (510) is configured to exert a radially outward force on the liner (20, 120, 220, 320, 420).

Retrievable stent system

The present invention relates to a system for treating a body lumen, comprising an implantable stent (10, 110, 210, 310, 410), including a tubular scaffold having a first flared end region (14), a second flared end region (16) and a medial region (18) extending between the first flared end region (14) and the second flared end region (16), and a liner (20, 120, 220, 320, 420) directly attached to the tubular scaffold at a first attachment point (30) and a second attachment point (32), and wherein the liner is configured to be radially spaced from an inner surface (24, 124, 224, 324) of the tubular scaffold between the first attachment point (30) and the second attachment point (32) to define a tissue ingrowth region (36) between an outer surface (38) of the liner (20, 120, 220, 320, 420) and the inner surface (24, 124, 224, 324) of the tubular scaffold, and a retrieval stent (510) configured to be positioned within a lumen of the implantable stent (10, 110, 210, 310, 410) wherein the retrieval stent (510) is configured to exert a radially outward force on the liner (20, 120, 220, 320, 420).

Esophageal stent including an inner liner

An example medical device is disclosed as an expandable stent. The stent includes a tubular scaffold having an inner surface, an outer surface, and a lumen extending therein. The expandable stent also includes a liner disposed within the lumen of the tubular scaffold. Further, the liner is radially spaced from a medial region of the tubular scaffold to define a tissue ingrowth region along an uncovered portion of the medial region. Additionally, the liner extending along the tissue ingrowth region is configured to limit the amount of tissue ingrowth along the medial region of the scaffold.

Stent including anti-migration capabilities

An example medical device for treating a body lumen is disclosed. The medical device includes an expandable scaffold including first and second regions, each of the first and second regions include a plurality of interstices located therein. The medical device also includes a covering spanning each of the plurality of interstices of the first region. The second region is free of the covering. A biodegradable gripping material is disposed on an outer surface of the covering. Further, the expandable scaffold is configured to shift from a collapsed state to an expanded state and the second region is configured to contact an inner surface of the body lumen in the expanded state. Additionally, the gripping material is designed to initially prevent migration of the expandable scaffold upon implantation in the body lumen until the second region is secured to the inner surface of the body lumen.

Stent anchoring system

System, device and method for anchoring a stent

The present disclosure relates generally to stents, systems, and methods for anchoring devices within a body lumen by cooperation between the device and the body musculature. A device comprising an elongate tubular member may be deployed within a body lumen, where the body lumen includes a sphincter that regulates flow through the body lumen. The elongate tubular member includes a sleeve formed from a flexible membrane and one or more stents disposed at either or both ends of the sleeve. In some embodiments, the stents may be treatment stents configured to treat a portion of the body lumen. The elongate tubular member may be deployed within the body lumen such that the flexible membrane aligns with and moves in coordination with the sphincter, thereby increasing retention forces acting upon the elongate tubular member when the sphincter is closed to minimize treatment stent migration.

消化管治療のためのステント、システムおよび方法

【課題】改善された胃腸治療のためのステント、システムおよび方法を提供する。【解決手段】いくつかの実施形態において、ステントは、第２端部の反対側に第１端部を有する管状足場であって、第１端部と第２端部との間に内腔が延びている管状足場を含んでもよい。管状足場は、フレア部と、フレア部から延びている中間部であって、フレア部の第１直径が、中間部の第２直径を超える中間部と、を含んでもよい。ステントは、管状足場の表面に部分的に沿って延びているライナーであって、フレア部のアンカー領域から離間してフレア部で組織の内方増殖を促進するライナーをさらに含んでもよい。【選択図】図１Ａ

Adjustable mandrel for forming stent with anti-migration features

A mandrel for forming a stent with a tapered profile and one or more anti-migration features includes a first stent shaping segment having a first diameter, a second stent shaping segment having a second diameter less than the first diameter and a tapered segment disposed therebetween. A third stent shaping segment is releasably securable to the second stent shaping segment and has a third diameter greater than the second diameter. One or more movable pins are outwardly extendable from corresponding apertures formed within the tapered segment. An actuation element is engagable with the first stent shaping segment and includes a tapered surface configured to engage the one or more movable pins and support the one or more movable pins extended from the corresponding apertures.

Adjustable mandrel for forming stent with anti-migration features

A mandrel for forming a stent with a tapered profile and one or more anti-migration features includes a first stent shaping segment having a first diameter, a second stent shaping segment having a second diameter less than the first diameter and a tapered segment disposed therebetween. A third stent shaping segment is releasably securable to the second stent shaping segment and has a third diameter greater than the second diameter. One or more movable pins are outwardly extendable from corresponding apertures formed within the tapered segment. An actuation element is engagable with the first stent shaping segment and includes a tapered surface configured to engage the one or more movable pins and support the one or more movable pins extended from the corresponding apertures.

Stent anchoring system

The invention relates to a stent, the stent comprising a tubular stent body comprising a number of interwoven filaments defining cells therebetween, the tubular stent body configured to move between a collapsed configuration and an expanded configuration, and a plurality of barbs attached to one or more of the filaments, each barb having a first free end, a second free end, and a base portion, the base portion affixed to the filament, wherein the first free end and the second free end are unconstrained from adjacent filaments when the stent is in the expanded configuration, wherein the first free end and the second free end of the barbs are configured to be positioned radially inward of and under an adjacent filament when the tubular stent body is in the collapsed configuration and to extend radially outward beyond the tubular stent body when the tubular stent body is in the expanded configuration.

Stent anchoring system

The invention relates to a stent, the stent comprising a tubular stent body comprising a number of interwoven filaments defining cells therebetween, the tubular stent body configured to move between a collapsed configuration and an expanded configuration, and a plurality of barbs attached to one or more of the filaments, each barb having a first free end, a second free end, and a base portion, the base portion affixed to the filament, wherein the first free end and the second free end are unconstrained from adjacent filaments when the stent is in the expanded configuration, wherein the first free end and the second free end of the barbs are configured to be positioned radially inward of and under an adjacent filament when the tubular stent body is in the collapsed configuration and to extend radially outward beyond the tubular stent body when the tubular stent body is in the expanded configuration.

Stents, systems, and methods for gastrointestinal tract treatment

The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Stent anchoring system

An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member may include at least one barb attached thereto. The barb may be configured to be tucked under a filament of the stent during delivery of the stent and protrude radially from the stent, when the stent is deployed.

Retrievable stent system

Stents, systems, and methods for gastrointestinal tract treatment

The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Devices, systems, and methods for pyloric occlusion

An occlusion device including a first component configured to anchor the occlusion device with respect to a deployment site, and a second component configured to occlude a lumen through the occlusion device. The first component may be in the form of a stent. The second component may be in the form of a stent or in the form of a liner within the first component. The second component includes an occlusion structure configured to extend across (e.g., transverse to the longitudinal axis of) the lumen of the first component. The occlusion structure may be on a retention member of the second component which engages with a retention member of the first component. Additionally or alternatively, the occlusion structure may be a portion of a liner cinched to occlude the lumen through the occlusion device.

Adjustable mandrel for forming stent with anti-migration features

Stent anchoring system

An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member may include at least one barb attached thereto. The barb may be configured to be tucked under a filament of the stent during delivery of the stent and protrude radially from the stent, when the stent is deployed.