ДВУХКАМЕРНЫЙ КОНТЕЙНЕР ДЛЯ ДОЗИРУЕМЫХ АЭРОЗОЛЕЙ, НЕ СОДЕРЖАЩИХ ПРОПЕЛЛЕНТА

Изобретение относится к двухкамерному контейнеру для жидкостей, в частности, лекарственных составов для применения в дозируемых аэрозолях, не содержащих пропеллента. Контейнер состоит из емкости с запорным колпачком для дозирования жидкостей, находящегося внутри окружного выступа, который в закрытом положении заходит снизу под цилиндрическое кольцо, жестко связанного с запорным колпачком штуцера, вытесняющего, во время надвигания запорного колпачка на горловину емкости, часть содержимого емкости, согласно изобретению штуцер содержит по меньшей мере одну камеру, герметизированную от внешнего пространства двумя протыкаемыми канюлей перегородками. Техническим результатом изобретения является обеспечение возможности надежного хранения и применения дозируемых аэрозолей, не содержащих пропеллентов, за счет плотного запирания емкости. 3 с. и 12 з.п. ф-лы, 4 ил.

СИСТЕМА ДЛЯ ПРИГОТОВЛЕНИЯ И ПРИВЕДЕНИЯ В ГОТОВЫЙ ВИД ТЕКУЧЕЙ СРЕДЫ, ОБРАЗОВАННОЙ СМЕШИВАНИЕМ СУХОГО ВЕЩЕСТВА И ЖИДКОСТИ

Изобретение относится к медицине и фармацевтической промышленности, а именно к системе для приготовления и приведения в готовый вид текучей среды (43), образованной смешиванием сухого вещества (39) и жидкости (41), в особенности среды для терапевтических целей, которая содержит следующие компоненты: а) первый контейнер (1) для приема жидкости (41) с участком (3) стенки, деформируемым для изменения объема против действия возвратного усилия; b) второй контейнер (35) для приема сухого вещества (39); с) передаточное устройство для установления сообщения между первым контейнером (1) и вторым контейнером (35). 3 н. и 13 з.п. ф-лы, 11 ил.

СИСТЕМА ПЕРЕМЕЩЕНИЯ СОДЕРЖИМОГО КОНТЕЙНЕРОВ

Изобретение относится к области приготовления медицинских составов. Система перемещения содержимого контейнеров содержит первый и второй контейнер, которые могут быть соединены друг с другом с возможностью перемещения среды посредством соединительного устройства, которое содержит устройство перемещения содержимого, которое, будучи удерживаемо при помощи запирающего устройства в заблокированном положении, препятствует обмену сред или делает возможным обмен сред в разблокированном положении. При этом запирающее устройство выполнено с возможностью перевода в разблокированное положение путем перемещения контейнера; на указанном подвижном контейнере предусмотрены дополнительные средства управления, которые по меньшей мере частично охватывают этот контейнер снаружи и воздействуют на запирающее устройство устройства перемещения содержимого с обеспечением его разблокирования. Соединительное устройство в качестве приемной части устройства перемещения содержимого и запирающего устройства содержит ...

УСТРОЙСТВО ДЛЯ БЕЗОПАСНОЙ ОБРАБОТКИ ЛЕКАРСТВ

Изобретение относится к медицинской технике, а именно к системам смешивания лекарств. Система смешивания лекарств содержит, по меньшей мере, один элемент сопряжения с гнездом емкости с жидкостью, по меньшей мере, один элемент сопряжения с ампулой с лекарством и, по меньшей мере, один элемент сопряжения со шприцем, выполненный с возможностью прикрепления к шприцу и к, по меньшей мере, одному из следующих компонентов: по меньшей мере, одному элементу сопряжения с гнездом емкости и, по меньшей мере, одному элементу сопряжения с ампулой. По меньшей мере, один из следующих компонентов: по меньшей мере, один элемент сопряжения с гнездом емкости, по меньшей мере, один элемент сопряжения со шприцем и, по меньшей мере, один элемент сопряжения с ампулой снабжен воздуховодом в окружающую среду, выполненным с возможностью предотвращения пропускания в окружающую среду потенциально вредного содержимого ампулы в жидкой, твердой или газообразной форме. Изобретение позволяет работать с токсичными лекарствами ...

РЕГУЛИРУЕМОЕ НЕКЛАССИФИЦИРОВАННОЕ НАПОЛНЯЮЩЕЕ УСТРОЙСТВО И СПОСОБ

Изобретение относится к области стерильного или асептического наполнения веществами закрытых контейнеров и устройств. Способ наполнения устройства включает в себя пронизывание инжекционным элементом (62) эластичной перегородки (62) устройства с образованием герметичной, пустой, стерильной камеры (11), сообщающейся по текучей среде с эластичной перегородкой (32). При пронизывании образуют кольцевую поверхность контакта между эластичной перегородкой (32) и инжекционным элементом (62), проходящую в осевом направлении между точкой проникновения на внутренней поверхности эластичной перегородки в сообщении по текучей среде со стерильной камерой (11) и наружной поверхностью перегородки, входящей в соприкосновение с инжекционным элементом (62), и обеззараживают инжекционный элемент (62), по меньшей мере, за счет одного из (i) трения между эластичной перегородкой (32) и инжекционным элементом (62) на кольцевой поверхности контакта и (ii) вытягивания эластичной перегородки (32) на кольцевой поверхности ...

КОНТЕЙНЕР С ПОЛОЙ ИГЛОЙ

Изобретение относится к медицинским контейнерам для размещения и выдачи лекарства, в частности парентерального. Контейнер содержит полую иглу в зоне отверстия, а также запечатанную, за исключением отверстия для выдачи лекарства, цельную оболочку. Контейнер выполнен с возможностью выдачи лекарства при изменении, по меньшей мере, одной зоны оболочки и имеет возможность достижения или, по меньшей мере, инициирования выдачи лекарства за счет нажатия на твердую и упругую половину оболочки, которая входит в другую половину оболочки, принимая противоположную направленную внутрь контейнера кривизну, и самопроизвольно продолжает выдачу определенного объема лекарства. Раскрыто применение контейнера с инфузионной или инъекционной иглой для инфузии или инъекции лекарства. Технический результат заключается в упрощении конструкции и облегчении введения лекарства. 2 н. и 11 з.п. ф-лы, 6 ил.

СПОСОБ ИЗГОТОВЛЕНИЯ КОНТЕЙНЕРА (ВАРИАНТЫ)

В способе формуют корпус, включающий камеру, в первой пресс-форме в чистой комнате и формуют часть контейнера во второй пресс-форме в чистой комнате того же класса, что и первая, при этом в части контейнера устройством для заполнения контейнера может быть выполнен прокол с образованием отверстия с возможностью восстановления ее герметичности. Затем собирают вместе часть контейнера и корпус в чистой комнате для получения пустой герметично закрытой камеры. Изобретение обеспечивает повышение герметичности, когда в части контейнера выполняют прокол. 14 з.п. ф-лы, 66 ил.

ИНФУЗИОННАЯ СИСТЕМА И ЕЕ КОМПОНЕНТЫ

Группа изобретений относится к области медицины, а именно к инфузионным системам для доставки нескольких лекарственных средств пациенту. Система содержит два резервуарных комплекта, включающих впускной соединитель, выполненный с возможностью взаимодействия с резервуаром для лекарственного средства, содержащим резервуарный порт и лекарственное средство, при этом впускной соединитель выполнен с возможностью соединения, по меньшей мере, с частью порта резервуара для лекарственного средства. Каждый впускной соединитель содержит иглу, предназначенную для приема лекарственного средства, и зацепляющий элемент, выполненный с возможностью взаимодействия с частью резервуара для лекарственного средства, для соединения впускного соединителя с резервуаром для лекарственного средства. Первый впускной соединитель дополнительно содержит обратный клапан для обеспечения перетекания лекарственного средства из резервуара для лекарственного средства в ответ на приложение порогового давления жидкости к первому ...

СПОСОБ ЛИОФИЛИЗАЦИИ И ГЕРМЕТИЗАЦИИ ВПРЫСКИВАЕМОГО ПРОДУКТА И КОНТЕЙНЕР ДЛЯ ЛЕОФИЛИЗАЦИИ И ГЕРМЕТИЗАЦИИ ВПРЫСКИВАЕМОГО ПРОДУКТА

Изобретение относится к герметизации и распределению лиофилизированного лекарства в контейнере. Технический результат заключается в повышении надежности. Технический результат достигается за счет того, что способ осуществляют с применением устройства усовершенствованной конструкции. Лиофилизацию проводят в контейнере, который устанавливают в камере, удаляют кислоту из контейнера и вводят азот, закрывают колпачок путем создания давления, выпускное отверстие блокируют от сообщения с первым отверстием в контейнере. Согласно изобретению вводят наконечник штока плунжера, имеющий головку в гильзе так, что наконечник штока плунжера выступает из второго отверстия в контейнере, причем головка расположена аксиально смежно с плунжером. Устанавливают контейнер в открытый конец гильзы. Контейнер аксиально удерживается в гильзе против выступающего радиально внутрь упора на гильзе и прочно закрепляют гильзу на колпачке. 2 с. и 6 з.п. ф-лы, 14 ил.

УСТРОЙСТВО ДЛЯ ПЕРЕКАЧКИ РАСТВОРА ИЗ ОДНОГО ГЕРМЕТИЗИРОВАННОГО КОНТЕЙНЕРА В ДРУГОЙ

Использование: в устройствах для транспортировки растворов из одного герметичного контейнера в другой. Сущность изобретения: устройство включает цилиндрический корпус, диск и смонтированные в нем иглообразные трубки для транспортирования раствора из одного контейнера в другой и подачи газа в контейнер. Цилиндрический корпус и диск образуют полости для приема контейнера. Трубка может быть укреплена наклонно в теле диска и ее концы расположены с противоположных сторон диска, параллельно его оси. На наружной цилиндрической поверхности диска может быть образовано отверстие, диаметр которого больше диаметра трубки для подачи газа. 2 з.п. ф-лы, 7 ил.

ГЕРМЕТИЧНЫЙ КОНТЕЙНЕР И СПОСОБ ЕГО ИЗГОТОВЛЕНИЯ ИЗАПОЛНЕНИЯ

... 1. Пузырек в сборе для хранения вещества, содержащий корпус, снабженный отверстием, камеру, в которую через отверстие может быть введено вещество, основание, среднюю часть и верхнюю часть, которая отделена в направлении оси от основания средней частью, причем размеры основания и верхней части в горизонтальной плоскости больше, чем максимальный размер средней части в горизонтальной плоскости, и заглушку, которая введена в отверстие и в которой иглой или иным подобным элементом может быть выполнен прокол для осуществления, по крайней мере, одного из следующих действий: введения в камеру вещества или извлечения его из камеры. 2. Пузырек в сборе по п.1, отличающийся тем, что поперечное сечение основания, средней части и верхней части имеет примерно форму окружности, и максимальный диаметр основания и верхней части больше максимального диаметра средней части. 3. Пузырек в сборе по п.2, отличающийся тем, что основание, средняя и верхняя часть создают форму, сходную с катушкой. 4. Пузырек в сборе ...

ЗАЩИТНАЯ ОБОЛОЧКА, ЗАЩИТНЫЙ МОДУЛЬ, СНАБЖЕННЫЙ ТАКОЙ ОБОЛОЧКОЙ, СИСТЕМА ПОДАЧИ ЛЕКАРСТВЕННОГО РАСТВОРА И СПОСОБ ПОДАЧИ ЛЕКАРСТВЕННОГО РАСТВОРА

... 1. Защитная оболочка для вмещения емкости для лекарственного раствора, содержащей лекарственный раствор и имеющей соединительный патрубок, через который выпускают лекарственный раствор, содержащая:корпус оболочки, вмещающий емкость для лекарственного раствора и имеющий отверстие, открытое наружу для вставления емкости для лекарственного раствора;закрывающую часть, закрывающую указанное отверстие;удерживающую часть, удерживающую емкость для лекарственного раствора, помещенную в корпус оболочки внутрь корпуса оболочки;соединительную часть, которая прикреплена к корпусу оболочки и может быть соединена с выпускным патрубком емкости для лекарственного раствора, так что лекарственный раствор, находящийся в емкости для лекарственного раствора, может быть выпущен наружу из корпуса оболочки; иподвешивающую часть, обеспеченную на корпусе оболочки для подвешивания указанного корпуса оболочки.2. Защитная оболочка по п. 1, в которой корпус оболочки выполнен из материала, имеющего, по меньшей мере, одно ...

СИСТЕМА И СПОСОБ ДЛЯ ПОДГОТОВКИ ИНЪЕКЦИИ

СИСТЕМА ПЕРЕМЕЩЕНИЯ СОДЕРЖИМОГО КОНТЕЙНЕРОВ

УСТРОЙСТВО ДЛЯ СОЕДИНЕНИЯ ЕМКОСТИ С КОНТЕЙНЕРОМ И СОЕДИНИТЕЛЬНЫЙ БЛОК, СОДЕРЖАЩИЙ ТАКОЕ УСТРОЙСТВО

Transfer- und Entnahmespike

FLÜSSIGKEITSABGABEVORRICHTUNG MIT EINGEBAUTER PHIOLENBEFESTIGUNG ODER EINGEBAUTEM PHIOLENADAPTOR

VORRICHTUNG ZUM ZUSAMMENBRINGEN VON STOFFEN, WIE ARZNEIMITTELN, MIT EINER FLUESSIGKEIT.

Zweikammer-Spritzampulle

NADELLOSE ZUGRIFFSVORRICHTUNG FÜR EIN MEDIZINFLÄSCHCHEN

VORRICHTUNG ZUM MISCHEN UND ABGEBEN VON ZWEI SUBSTANZEN IM STERILEN ZUSTAND

Device with a daily medicament depot for low-pain injection

The invention relates to a device with a daily medicament depot for low-pain injection. The device filled with a medicament can also be worn on the body, has a low weight and is built on the fountain-pen principle. It comprises a dust-proof, thermally insulating casing with an exchangeable, multi-layer, disinfecting, sterile fumigation pad, an inert glass or plastic cylinder with an outside that is firmly gripped, a teflon-coated piston rod and a teflon-coated metal cone, as well as a tuned optical and acoustic display system for the individual determination of the amount to be injected. The tuned optical system has a graduation in units of medicament on the unilaterally flattened threaded spindle which correlates with the medicament volume of the syringe. The acoustic system is a bayonet closure with a marking spring extending in a sound space on the unilaterally flattened threaded spindle. The fumigation pad is also used to disinfect the injection site. The puncturing direction can be ...

GLEITENDE UND ABDICHTENDE WIEDERHERSTELLUNGSANORDNUNG.

System zur sterilen Abnahme von Körperflüssigkeit

Transfervorrichtung, insbesondere für medizinische Fluids

Überleitungsgerät zum Mischen von in unterschiedlichen Behältern befindlichen Medikamenten

Injektionsstelle

Stumpfer Einstechdorn.

Verbinder mit Verriegelungsring für eine Phiole

Viele Positionen aufweisende und wiederverschliessbare Phiolenverbindung zur effizienten Übertragung von Flüssigkeit

Einstückige Appliziervorrichtung zur kontaminationsfreien Verabreichung von in fester Ausgangsform vorliegenden Arzneimitteln, insbesondere Zytostatika

STABILIZED LIQUID MIXING SYSTEM

Pre-filled syringe system

Needle sheath

Improvements in or relating to medicament packages

... 490,020. Surgical syringes ; manufacture of medicaments. COOK LABORATORIES, Inc. Feb. 5, 1937, No. 3537. Convention date, Nov. 17, 1936. [Classes 81 (i) and 81 (ii)] A medicament package, employable in adding to injections and the like, modifying agents immediately before use, comprises a tube 1 closed at one end by a flanged or other non-slidable plug 3 and having a slidable plug 6 near the other end, the enclosed space, filled with medicament, being less than the total capacity of the tube, and the tube carrying or being adapted to carry, an end stop such as 17 which prevents the plug 6 from leaving the tube. Preferably an end stop 17 is provided at each end of a clip 10 on the tube, at least one stop being perforated for the passage of a needle. In use a modifying liquid is injected, by a needle syringe 8, into the tube 1 held in the clip 10 until the plug 6 touches the stop 17, the tube being subsequently used for example in an injection syringe similar to 8. Preferably plug 6 is spaced ...

INJECTOR DEVICE

IMPROVED PROTECTIVE SHEATH FOR A CANNULA

A protective device for enclosing the scarf (86) of a cannula (70) includes an elongated sheath (82) having a bore (71) extending through it. The cannula (70) is sealed in the bore (71) of the sheath (82) with the scarf end of the cannula (70) located within and adjacent one end of the sheath (82), which is spaced from the scarf (56). The end of the sheath adjacent the scarf end of the cannula has at least one cutout (84) portion which can receive the edge of a flexible bag or a flexible tubing connected to a Y-site for intravenous injection. A socket (92) carried by the sheath (82) at the other end of the cannula (70) has an opening through it in communication with the bore (71) through the cannula (70). The socket opening (92) tapers outwardly away from the cannula (70) for receiving a tapered nozzle on a syringe. Preferably, the sheath (52) surrounds the socket (92) and carries inwardly extending ears (96) which act as male threads for engaging internal threads in a skirt around the ...

APPARATUS FOR MIXING TWO SUBSTANCES

Liquid transfer devices for use with infusion liquid containers

Additive transfer unit

An additive transfer unit for transferring a measured volume of a liquid medicament into an evacuated container comprises a liquid storage container 10, a rigid disc 24 closing the mouth of the container, a rigid piercing member 30 formed integrally with the disc and having a passageway 32, a penetrable protective tip 48 providing a seal over a needle point 31 on the piercing member, and a metal closure 42. An elastic sealing means 34 around and contiguous the outside diameter of the disc provides, with the disc, a fluid-tight seal over the mouth of the container, the disc including a cylindrical hub 50 to stabilize the sealing means against the metal closure. The protective tip 40 includes a portion deflecting radially outwardly of the piercing member in response to a positive pressure differential in the interior of the container, thereby venting a portion of the container contents into a cavity between the metal closure and piercing member. In use, point 31 pierces tip 40 which slides ...

A transfer device and dispensing system for the transfer of aliquots from a container of fluid

A transfer device for withdrawal of aliquots from a container of bulk solution is provided with a body having a tapered chamber, a first passage venting the smaller end of the chamber to the surrounding air, a second passage communicating at one end with the larger end of the chamber, and a third passage having one end for withdrawal of fluid therefrom. A tapered valve element is received within the chamber for movement between first and second conditions in response to changes in the presence differential between the first and second passages. The first condition provides a fluid seal between the first and second passages by engagement of the valve element with the walls of the chamber for pressures within the second passage greater than that within the first passage, and the second condition provides a fluid path from the first passage to the second passage for pressures within the second passage somewhat less than that within the first passage. The device further includes structure placing ...

LIQUID CONTAINMENT SYSTEMS

APPARATUS FOR CONTACTING MATERIAL SUCH AS A DRUG WITH A FLUID

Fluid transfer assembly

Syringes

LIQUID RESERVOIR DRAINAGE DEVICE

Syringe unit

... 800,455. Syringes. MERCK & CO., Inc. Sept. 6, 1955 [Sept. 15, 1954], No. 25538/55. Class 81 (2). [Also in Group XVII] A syringe unit comprises two containers 1, 5, one of which has a nozzle 2 insertable into the nozzle 6 of the other, the two nozzles forming a spigot-and-socket joint which is moisture-tight and airtight and provides a passageway between the interiors of the containers, one of which is squeezable to eject the contents when separated from the other. A collapsible container 1 for a solid, powdered or crystalline ingredient is made of tin, tin-coated lead, aluminium or plastic and has a rigid nozzle 2. A resilient container 5 for a liquid ingredient is made of rubber or polyethylene and has a rigid nozzle 6. After removing a cap (not shown) from each nozzle 2, 6, one nozzle 2 is fitted into the other nozzle 6, the nozzles having complementary tapers. The resilient container 5 is squeezed to eject liquid into the collapsible container 1. On release, the resilient container 5 ...

INFUSORS FOR USE IN TRANSFERRING MEDICAMENTS

Syringe with integrally formed piercing member and luer slip.

Improvements relating to luer connectors.

A leur connector comprising a luer connectable to a syringe and which extends a sharpened en capable of being driven through a puncturable vial closure to thereby puncture the closure; a luer support, mountable on a vial, and which initially supports the luer in a first position in which the sharpened end of the conduit is pointed toward the closure; a leur driver such that movement of the driver relative the supporth causes the luer to be driven so that the sharpened end punctures the closure and enters the vial. The leur connector facilitates connection of a posdermic syringe to the vial.

ADAPTOR FOR COUPLING WITH A MEDICAL CONTAINER

Novel device

Adaptor for coupling with a medical container

Syringe with integrally formed piercing member and luer slip.

Syringes

Novel device.

Adaptor for coupling with a medical container

Adaptor for coupling with a medical container

Novel device

Syringe with integrally formed piercing member and luer slip.

TRANSITION EQUIPMENT FOR AND MEDICAL CONTAINERS FELL

CONNECTING MECHANISM TO THE MEDICAL USE AND TO THE TRANSFER OF LIQUIDS

SYSTEM AND PROCEDURE FOR MIXING AT LEAST FOUR COMPONENTS

KIT WITH A SYRINGE NEEDLE WITH SEITENÖFFNUNG FOR PREPARING A MEDICINE IN AN INJECTION PIN CARTOUCHE

DEVICE TO THE WITHDRAWAL OF LIQUIDS FROM A CONTAINER

FLUID DATA COMMUNICATION EQUIPMENT

Device for the injection of two substances

VORRICHTUNG ZUR UEBERLEITUNG VON STERILEN FLUESSIGKEITEN IM GESCHLOSSENEN SYSTEM

AUF EINE INJEKTIONSSPRITZE, EINE SPRITZAMPULLE ODER EIN SONSTIGES INJEKTIONSGERAT AUFSETZBARE TULLE ZUM INJIZIEREN EINER FLUSSIGKEIT

FLUIDUEBERTRAGUNGSEINRICHTUNG

MORE PHIOLENADAPTER WITH NEEDLE-FREE VALVE FOR USE WITH PHIOLENVERSCHLÜSSEN WITH DIFFERENT GRÖßEN

DEVICE FOR FILLING A SUBSTANCE OVER

PERFORATE-CASH CATCH

SYSTEM FOR PREPARING AND MAKING A BY MIXING AVAILABLE A TROCKENSUBSTANZ WITH A FLUID EDUCATION OF FLUID MEDIUM

FORM CONTAINER WITH EDIFYING NIPPLE AND USE

PROCEDURE FOR THE PRODUCTION OF AUTO+LIED FIBRINKLEBERN

TRANSFER NEEDLE

SAFETY PROTECTION FOR MEDICAL NEEDLES

PLASTIC NEEDLE AND DEVICES WITH THIS

VORRICHTUNG ZUR ENTNAHME VON FLUESSIGKEITEN AUS EINEM BEHAELTER

DEVICE TO THE DELIVERY FROM LIQUID DRUGS TO THE USE WITH SYRINGES WITH EXTENDED DISTAL ONE POINTS

CONTAINER FOR TO GIVING LIQUID MEDICINES

System and method for sterile decrease of body fluid

System (1) zur sterilen Abnahme von Körperflüssigkeit und zum Abtrennen eines Teils der abgenommenen Körperflüssigkeit. Das System (1) umfasst eine Abnahmespritze (2) mit einem Gehäuse (3) und einem an einer Kolbenstange (5) befestigten Kolben (4), welcher in dem Gehäuse (3) verschiebbar ist, wobei in der Kolbenstange (5) ein Kolbenkanal (12) ausgebildet ist, der in Längsrichtung durch die Kolbenstange (5) verläuft, ein Zwischenelement (24), welches über eine erste Kupplung (30) mit der Kolbenstange (5) koppelbar ist, und einen Behälter, welcher über eine zweite Kupplung (36) mit dem Zwischenelement (24) koppelbar ist. Die zweite Kupplung (36) weist einen Einstichteil (27) mit einer Spitze (28) und einen Verschlussteil (9) mit einem Verschluss (10) auf. Die erste Kupplung (30) ist gleich aufgebaut wie die zweite Kupplung (36).

LIQUID TESTING DEVICE WITH MANUALLY OPERATED CAUSE

ON AN INJECTION SYRINGE, A SPRAYING AMPUL OR AN OTHER INJECTION-TURN OUT PUT ON-CASH TULLE FOR INJECTING ONE FLUSSIGKEIT

EQUIPMENT FOR THE DELIVERY CELEBRATIONS OF A MEDICINE COMPOSITION

GAS-FILLED SYRINGE AND PACKING

SLIDING RE-ESTABLISHMENT DEVICE FOR A DILUENT CONTAINER

MEDICINE CONTAINER AND ADMINISTRATION SYSTEM

TRANSFER DEVICE BY SUCKING.

STORAGE SYSTEMS.

HILFSVORRICHTUNG ZUM STERILEN UEBERFUEHREN VON LOESUNGEN IN EIN LOESUNGSMITTEL ENTHALTENDES GE- FAESS

DEVICE FOR THE TRANSITION OF STERILE LIQUIDS IN THE CLOSED SYSTEM.

Methods for exposing and using a swab

A method for remotely applying a force to a tether affixed to a sterilizing swab package to open the package for use of a swab disposed therein. The method may be applied to sterilizing a septum of a vial disposed within a bag.

Syringe drive device

A syringe drive device 1 includes a cylinder holding section 3 configured to detachably hold a cylinder 201, a piston manipulating section 4 detachably coupled with a piston, and a piston drive section 5 including racks 31 A and 31 B coupled with the piston manipulating section 4 and configured to move the piston manipulating section 4 so that a piston 202 is moved in a push-in direction or a pull-out direction. A cylinder 200 A having a given capacity (for example, 50 cc) is directly loaded in the syringe drive device 1 with no adapter therebetween. A syringe 200 C having a different capacity (for example, 20 cc) is loaded in the syringe drive device 1 by means of a cylinder adapter 81 and a piston adapter 82.

Systems and methods for preparing autologous fibrin glue

A method of regenerating tissue in a living organism. The method includes the act of contacting an affected area of the living organism with a solid-fibrin web, the solid-fibrin web comprising platelets that release growth factors about one minute after contact to regenerate the tissue in the living organism.

Device for removing fluids from vials

The invention relates to a device for removing a fluid from at least one container ( 300 ), for example, from a vial, that has a seal that can be punctured. The device comprises a base body ( 210 ), in which a fluid channel is formed. In order to reduce the lost volume, a pin-shaped insertion element ( 250 ) that reduces the cross-section of the fluid channel is inserted into the fluid channel through an insertion opening. Locking structures ( 262, 263 ) that retain the container on the device in a removal position and in a storage position different therefrom can be provided so that the container can be stored on the device without the seal being punctured accidentally. Such a device can be used in particular to fill an applicator ( 100 ) having one or more fluid reservoirs from one or more vials.

System and Method for Intermixing the Contents of Two Containers

A system and method for intermixing the contents of two containers. The system includes a first container, a second container, and a connector for providing fluid communication between the first and second containers. The connector includes at least one resilient retention member for securing the first container to the connector. In addition, the connector accommodates standard vials containing, for example, medicaments, and prevents the unwanted discharge of the contents of the vial into the environment.

Systems and methods for safe medicament transport

A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

Connector for a container including a medicinal active ingredient

The invention relates to a connector for containers containing medicinal active ingredient, which connector makes it possible to transfer active ingredient from one container into another container. The connector ( 1, 1 ′) according to the invention comprises a first connection region ( 3, 3 ′) for the connection of a first container ( 2, 2 ′), a guide element ( 4, 4 ′), a piercing element ( 5, 5 ′) and a partition wall ( 6 ), wherein the guide element ( 4, 4 ′) has a duct ( 7 ) designed for transferring a medicinal active ingredient, the piercing element ( 5, 5 ′) is arranged, at least in certain sections, in the duct ( 7 ) and is axially movably guided within the duct ( 7 ) by the guide element ( 4, 4 ′), and, by connecting a container ( 2, 2 ′) in the first connection region ( 3, 3 ′), the piercing element ( 5, 5 ′) can be moved from a starting position, in which the piercing element ( 5, 5 ′) does not open the partition wall ( 6 ), into an end position, in which the piercing element ( 5, 5 ′) opens the partition wall ( 6 ) in order to transfer a medicinal active ingredient.

Device

The present application is directed to devices. The device may used for connecting a closed receptacle and a container, such as a syringe.

Drug solution delivery device for medical use

A cylindrical body ( 30 ) that is inserted into a drug solution container ( 70 ), a connection port ( 15 ) to which a syringe ( 40 ) is connected, and a connector ( 50 ) that is connected to a port ( 110 ) of an infusion bag ( 100 ) communicate with a cavity ( 11 ) of a delivery device main body ( 10 ). A first check valve ( 21 ) that functions to permit the flow of drug solution toward the cavity from the drug solution flow path and restrict the flow of drug solution in the opposite direction is provided on a flow path between a drug solution flow path ( 31 ) of the cylindrical body and the cavity. A second check valve ( 22 ) that functions to permit the flow of drug solution toward the connector from the cavity and restrict the flow of drug solution in the opposite direction is provided on a flow path between the connector and the cavity. Drawing a plunger ( 45 ) of the syringe in and out enables a drug solution ( 72 ) contained in the drug solution container to be efficiently transferred to the infusion bag.

System and method for mixing the contents of two containers

A system for mixing contents of a first container with contents of a second container. The system includes a first container, a second container, a device for establishing fluid communication between the first container and the second container, and a hanger for hanging the system, wherein the hanger is operable only when fluid communication between the first container and the second container has been established. The system can be used in a method for preventing medication delivery errors.

Package for Delivering Microdoses of Medicament

A primary package for simultaneously dispensing microdoses of from 5 to 500 microliters of one medicament contained in a medicated module and another medicament contained in an attached injection system is disclosed, where the primary package contains a single dose of medicament contained within a reservoir cavity sealed with closure caps that secure top and bottom septa.

Medical Device Connector

The present invention relates to a medical device connector for connecting a piercing device ( 3 ), with a vial ( 2 ) comprising a base member. A plurality of grip members ( 50 ), each grip member ( 50 ) comprising a distal end (D) and a proximal end (P) and each comprising a wedge portion ( 61 ) adapted to temporarily or permanently lock the medical device connector ( 1 ) to the vial ( 2 ). The base member ( 30 ) further comprises a plurality of flanges ( 40 ), wherein the proximal ends (P) of the grip members ( 50 ) are arranged to the flanges ( 41, 40 ). The flanges ( 40 ) extend substantially out from the periphery of the base member ( 30 ) in a direction substantially perpendicular to the direction of the grip members, wherein the space formed between the flanges ( 40 ) of the base member ( 30 ) forms at least one grip portion. The present invention provides for a medical device connector ( 1 ) which is easy and comfortable to use, which provide good stacking capabilities and which permits a user to readily acknowledge that the medical device connector ( 1 ) is correctly assembled with the vial ( 2 ).

Medicine storage container

A liquid medicine storage container has a container body and a medicine stored in the container body. The container body includes a first space provided on the distal end, into which a liquid is injected, a second space provided more to the proximal end than the first space, for storing the medicine, and at least one guide passage that communicates the first space and the second space and that guides a liquid injected from the first space to an inner surface of the second space. The container body is configured so that the liquid guided to the inner surface is supplied to the medicine by flowing along the inner surface. A plurality of guide passages is arranged with intervals therebetween along a circumferential direction of the container body.

Medical Vial Access Device with Pressure Equalization and Closed Drug Transfer System and Method Utilizing Same

A vial access device includes a housing having first and second connectors. The first connector is configured to be secured to a first container and the second connector is configured to be secured to a second container. The vial access device further includes a spike member extending from the housing and having a proximal end and a distal end. The spike member defines a vent lumen and a fluid lumen spaced from the vent lumen with each of the vent lumen and the fluid lumen having a distal opening. A shape defined by a circumference of the spike member is only symmetric about one axis at a position between the proximal end of the spike member and the distal opening of the fluid lumen.

Drug storage container

A drug storage container includes: a first container; a second container that is disposed on the lower end side of the first container; a needle tube for making an internal space of the first container and an internal space of the second container communicate with each other; operating means for performing an operation of bringing the first container closer to the second container; a drug stored in the internal space; and a liquid stored in the internal space. In the drug storage container, with the first container and the second container brought closer to each other by the operating means, the internal space of the first container and the internal space of the second container are made to communicate with each other through the needle tube, and the volume of the internal space of the second container is reduced.

Two-piece vial transfer needle assembly

The present disclosure relates to a vial transfer needle assembly including a first molding member and a second molding member. The first molding member includes a hub portion that has a proximal piercing tip and a distal portion. The hub portion defines a lumen that passes therethrough. The second molding member includes a central housing, a proximal skirt, and a distal skirt. The second molding portion is molded at least partially about the first molding portion to form a monolithic structure. The piercing tip is positioned to extend into a first cavity that is defined by the proximal skirt. The distal portion of the first molding member is positioned to extend through a second cavity that is defined by the skirt. The distal skirt is dimensioned to receive a medical device.

Fluid Container Devices, Methods and Systems

A drug container assembly for use with a parenteral drug delivery device is disclosed. The container assembly includes a container configured to hold the medication and an intermediate port connector. The port connector may be fixedly coupled to the container and removably coupled to the delivery device in a convenient, reliable, and sealed manner In use, the port connector may convey the medication from the container to the delivery device for delivery to the patient. 1. A delivery port for use with a delivery device , the delivery port comprising:an inlet;an outlet;a pin;a first O-ring; anda second O-ring, wherein the port connector having a sealed configuration in which the first and second O-rings are positioned in sealed engagement with the pin to close the delivery port; an intermediate configuration in which the first O-ring is positioned in sealed engagement with the delivery device and the second O-ring is positioned in sealed engagement with the pin; and a delivery configuration in which the first O-ring is positioned in sealed engagement with the delivery device and the delivery port is positioned in fluid communication with a fluid passageway of the delivery device.2. The delivery port of claim 1 , wherein in the delivery configuration claim 1 , the first and second seals are positioned in sealed engagement with the delivery device.3. The delivery port of claim 1 , wherein in the delivery configuration claim 1 , the first seal is positioned in sealed engagement with the delivery device and the second seal is positioned in sealed engagement with the pin.4. The delivery port of claim 1 , wherein the port connector includes a shoulder that transfers movement of the port connector to the first O-ring.5. The delivery port of claim 4 , wherein the first and second O-rings are positioned on a same side of the shoulder.6. The delivery port of claim 4 , wherein the first O-ring is positioned below the shoulder and the second O-ring is positioned above the ...

Pressure-regulating vial adaptors

In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. The regulator assembly can include a valve configured to transition between a closed configuration and an opened configuration.

Adaptor for Coupling with a Medical Container

The invention relates to an adaptor for coupling with a medical container closed by a septum, the adaptor comprising:—a gripping member () for securing the adaptor to the medical container,—a needle access port intended to face an outer surface of the septum,—a pierceable elastomeric piece () having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess () with a proximal opening and an outer wall () in contact with the needle access port,—attaching means for maintaining the elastomeric piece into the needle access port. The invention also relates to an assembly comprising such an adaptor and a medical container, and to the use of such an adaptor for preventing the contamination inside a medical container closed by a septum. 1. An adaptor for coupling with a medical container , said medical container having a collar closed by a septum , said septum having an outer surface directed towards the outside of the medical container , the adaptor comprising:a gripping member for securing the adaptor to the medical container,a needle access port facing the outer surface of the septum when the adaptor is coupled to the medical container, anda pierceable elastomeric piece having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess with a proximal opening, an outer wall in contact with the needle access port, and a distal surface comprising a protruding part engageable with the outer surface of the medical container septum,wherein the elastomeric piece and the needle access port comprise an attaching arrangement for maintaining the elastomeric piece into said needle access port when a pressure is applied by the protruding part on the outer surface of the septum.2. The adaptor according to claim 1 , wherein a ratio between a height of said recess and a width of said recess ranges from 0.3 to 0.7.3. The adaptor according to claim 1 , wherein said recess comprises a bottom ...

TRANSFER SET

A transfer set generally includes an outer sleeve configured for connecting an inner sleeve to a vial such that a passage of the inner sleeve is disposed above a stopper of the vial. The transfer set further includes a cap configured for insertion into the outer sleeve such that the cap is connected to the outer sleeve and is detachable from the outer sleeve via rotation of the cap relative to the outer sleeve. The cap has an interior space and a cam disposed within the interior space, wherein the inner sleeve, and a spike within the inner sleeve, extend into the interior space when the cap is connected to the outer sleeve, and wherein, as the cap rotates relative to the outer sleeve for detachment of the cap from the outer sleeve, the cam interacts with the follower to translate the spike toward the stopper for puncturing the stopper. 1. A transfer set for transferring liquid into or out of a vial sealed by a stopper , the transfer set comprising:an inner sleeve comprising a passage extending through the inner sleeve along a longitudinal axis;an outer sleeve configured for connecting the inner sleeve to the vial such that the passage is disposed above the stopper of the vial;a spike comprising a follower, wherein the spike is disposed within the passage of the inner sleeve and is configured for longitudinal translation along the passage to puncture the stopper; and a closed top wall;', 'an annular side wall extending from the closed top wall to define an open bottom and an interior space of the cap; and', 'a cam disposed within the interior space,, 'a cap configured for insertion into the outer sleeve such that the cap is connected to the outer sleeve and is detachable from the outer sleeve via rotation of the cap relative to the outer sleeve, the cap comprisingwherein the inner sleeve and the spike extend into the interior space when the cap is connected to the outer sleeve, andwherein, as the cap is rotated relative to the outer sleeve for detachment of the cap ...

Apparatus for Transferring a Liquid Between a Storage Container and At Least One Further Use Container

An apparatus for transferring a liquid between a storage container and at least one further use container has a storage-container sealing portion for leaktight abutment of a main body of the transfer apparatus against the storage container. A hollow-needle assembly has a hollow needle. The hollow-needle assembly can be displaced in a linear manner along a movement axis relative to the main body by means of a gear mechanism between a retracted rest position and an extended connecting position. In the latter, the hollow needle creates a liquid connecting duct between the storage container and the transfer apparatus. A connecting portion serves to connect the transfer apparatus to the use container in a leaktight manner. A rotary-actuation element is operatively connected to the hollow-needle assembly via the gear mechanism. The gear mechanism has a driver ring that is mounted in the main body axially and so as to be rotatable about the movement axis. Said driver ring interacts with a complementary thread of the hollow-needle assembly for the displacement thereof. The driver ring is connected to the rotary-actuation element for conjoint rotation during the displacement. This results in a transfer apparatus having improved operational reliability, in particular when used by inexperienced patients. 1. An apparatus for transferring a liquid between a storage container and at least one further use container ,having a storage-container sealing portion for leaktight abutment of a main body of the transfer apparatus against the storage container; a retracted rest position and', 'an extended connecting position in which the hollow needle creates a liquid connecting duct between the storage container and the transfer apparatus,, 'having a hollow-needle assembly with a hollow needle, wherein the hollow-needle assembly is displaceable in a linear manner along a movement axis relative to the main body by means of a gear mechanism between'}having a connecting portion for connecting ...

PERFORATING NEEDLE FOR FLASK WITH SEPTUM

A perforating needle intended to be inserted into a flask through a stopper or septum to inject and remove a fluid includes a pointed end for piercing the stopper and a cylindrical body. The central body includes a central channel through which the fluid may enter and leave the flask and a side wall having at least one lateral orifice. The orifice is in fluid communication with the central channel. A lower end of the orifice is, in use, essentially level with an inner face of the stopper. The orifice is extended toward the pointed end by at least one slot, a shape of which is essentially tangential to a flow of the fluid so as to channel the fluid along an axis of the needle. The side wall includes at least two diametrically opposite lateral orifices arranged on either side of a central island. 1. A perforating needle intended to be inserted into a flask through a stopper or septum to inject and remove a fluid , the needle comprising:a pointed end configured to pierce the stopper; anda cylindrical body comprising a central channel through which the fluid may enter and leave the flask and a side wall comprising at least one lateral orifice, the orifice being in fluid communication with the central channel and a lower end of the orifice being, in use, essentially level with an inner face of the stopper, the orifice being extended toward the pointed end by at least one slot, a shape of which is essentially tangential to a flow of the fluid so as to channel the fluid along an axis of the needle,wherein the side wall comprises at least two diametrically opposite lateral orifices arranged on either side of a central island, the central island having a separating rim forming an angle of between 15° and 60°,wherein the separating rim penetrates the central channel, andwherein the slots extending the orifices emerge near the pointed end.2. (canceled)3. The perforating needle according to claim 1 , wherein the perforating needle is comprised of rigid plastic material.4. The ...

PRESSURE-REGULATING VIAL ADAPTORS

A vial adaptor can include a connector interface and/or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and/or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly. 1. A pressure-regulating vial adaptor comprising:a connector interface;a piercing member in communication with the connector interface; and a storage chamber;', 'a flexible enclosure positioned within the storage chamber in a contracted configuration and configured to expand in an expanded configuration;', 'an expansion inhibitor connected to a portion of the regulator assembly, the expansion inhibitor comprising one or more weakened portions configured to facilitate a tear in the expansion inhibitor when the flexible enclosure moves from the contracted configuration to the expanded configuration., 'a regulator assembly comprising2. The vial adaptor of claim 1 , wherein at least one of the one or more weakened portions is a perforation.3. The vial adaptor of claim 1 , wherein the expansion inhibitor extends over at least a portion of a side of the regulator assembly.4. The vial adaptor of any of claim 1 , wherein the expansion inhibitor includes an aperture when the flexible enclosure is in the contracted configuration.527.-. (canceled)28. A method of manufacturing a ...

CONNECTOR SECTION

A locking element for a connector configured to connect two components of a fluid transfer system and a connector that comprises the locking element are described. The connector comprising the locking element is configured to provide continuous fluid channels between a first component and a second component of a fluid transfer system, the fluid is a hazardous drug and the connector is designated for safe and contamination-free transfer of said hazardous drug from first to second container while isolating the needle tips and causing no dangerous and harmful leaks. 1. A locking element for a connector configured to connect two components of a fluid transfer system , the locking element comprising:a. a body comprising an upper part having a hollow interior and a lower part having a channel passing through it;b. elongated flexible arms having distal enlarged elements attached to the sides of the upper part of the body and projecting downwards parallel to the sides of lower part of the body; andc. an insert configured to be inserted into the channel, wherein the insert is made of flexible material and comprises at least one bore passing through it which forms a sleeve through which at least one hollow needle is able to pass;characterized in that the locking element comprises a rigid flat plastic annular disc at the free end of the lower part of the body.2. The locking element of claim 1 , comprising two bores through the insert.3. A connector configured to connect two components of a fluid transfer system claim 1 , the connector comprising:a. a hollow cylindrical body that has a closed upper end comprising an exterior side and an interior side, the upper end comprising a connection arrangement on the exterior side and a needle holder on the interior side, the connector section configured to connect to a first component of a fluid transfer system;{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'b. a locking element according to , wherein the body of the locking element ...

MIXING PEN NEEDLE

An injection device is provided with dual medicament chambers and a mixing pen needle assembly, whereby predetermined dosages of two medicaments can be provided to a mixing reservoir in the pen needle assembly and delivered simultaneously with the injection device. 1. A medication pen comprising:a pen body having a distal end and a proximal end, and having a first medication compartment and a second medication compartment;first and second dosing mechanisms and first and second dosage plungers engaged in the respective first and second medication compartments;a movable housing received on the distal end of the pen body adapted to be received in first and second positions on the pen body;a pen needle assembly received on the distal end of the movable housing, said pen needle assembly comprising a patient end needle, a filler needle, and a collapsible mixing reservoir intermediate and accessed by said patient end needle and said filler needle;wherein the movable housing is movable between a first position in which the filler needle is in fluid communication with the first medication compartment and a second position in which the filler needle is in fluid communication with the second medication compartment; andwherein collapsing the mixing reservoir forces medication in the mixing reservoir through the patient end needle during an injection.2. The medication pen according to claim 1 , wherein each medication compartment comprises a medication cartridge and each dosage plunger engages a respective medication cartridge.3. The medication pen according to claim 1 , further comprising a check valve on the filler needle preventing backflow from the mixing reservoir into the first and second medication compartments.4. The medication pen according to claim 1 , wherein the first and second dosing mechanisms comprise first and second rotatable knobs protruding from the proximal end of the pen body.5. The medication pen according to claim 1 , wherein the movable housing is ...

PREPARATION OF THERAPEUTIC FOAM

A device is described for facilitating the preparation of therapeutic foam e.g. for the treatment of varicose veins. A pressurised vial contains a sclerosant liquid, e.g., polidocanol solution, and a sterile gas which is readily absorbed by the body, e.g., carbon dioxide, oxygen or a mixture of these gases. The vial is provided either with a specialised stopper/seal into which a syringe nozzle may be inserted or alternatively a septum seal which may be penetrated by a hypodermic needle. The quantities of gas and liquid and the pressure in the vial are pre-set so that, on connection of a syringe to the vial, a predetermined volume of both gas and liquid is transferred to the syringe, with the intention that the syringe is then used to make a foam by known means. The use of the vial ensures that the ratio of gas to liquid in the foam is standardised, and also provides a convenient way of packaging the gas and liquid and of filling the syringe in a sterile manner. 1. A vessel having sterile contents , a first phase comprising a foamable sclerosant liquid solution, and', 'a second phase in contact with the first phase comprising a gas mixture consisting essentially of oxygen and carbon dioxide pressurized at a pressure above atmospheric pressure,', 'the vessel having a resilient closure, which is pierceable by a hollow hypodermic needle, and which forms a seal around the needle when it is pierced, and', 'wherein the vessel is configured for transfer of the sterile contents from the vessel to the syringe through the hypodermic needle inserted through the resilient, pierceable closure and into the foamable sclerosant liquid solution,', 'wherein the pressure of the gas mixture in the vessel is selected such that, upon piercing of the resilient closure by the hollow hypodermic needle and passage of the needle into the foamable liquid the pressurized gas mixture forces a volume of the foamable sclerosant liquid solution into the syringe, followed by the passage of a volume ...

TRANSFER DEVICE FOR MEDIA, COMPRISING A NON-RELEASABLY LOCKABLE ADAPTER

A transfer device () for removing or transferring a medium out of or into a bottle () having a bottle neck () that can be closed by means of a closure (), including a first adapter part (), which can be positioned on the bottle, and a second adapter part (), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element () for piercing the closure. After the second adapter part () has been displaced along the first adapter part in the direction of the closure () and the second adapter part has been locked, the first adapter part () is non-releasably fastened to or around the bottle (). 139.-. (canceled)4010100200400203442. A transfer device ( , , , ) for the withdrawal or delivery of a medium out of or into a bottle () with a neck () , that is sealable by a closure () , comprising:{'b': 12', '112', '212', '412, 'a first adapter component (, , , ) that can be positioned on the bottle, and'}{'b': 14', '114', '214', '414', '50, 'a second adapter component (, , , ), which interacts with the first adapter component, is moveable in the longitudinal direction of the bottle, and comprises a delivery element () for piercing the closure,'}{'b': 14', '114', '214', '414', '12', '112', '212', '412', '42', '20, 'wherein, after moving the second adapter component (, , , ) along the first adapter component (, , , ) in the direction of the closure () and locking of the second adapter component, the first adapter component is secured in position non-detachably at the bottle () or around the bottle,'}{'b': 10', '100', '200', '400', '20', '12', '112', '212', '412', '14', '114', '214', '414', '42, 'wherein the transfer device (, , , ) is secured in position at or around the bottle (), the first and the second adapter components (, , , ; , , , ) form an enclosed sealed envelope that surrounds the bottle at least in the area of the closure element (),'}{'b': 14', '214', '44', '46', '50, "the second adapter ...

CONNECTOR FOR A CONTAINER INCLUDING A MEDICINAL ACTIVE INGREDIENT

The invention relates to a connector for containers containing medicinal active ingredient, which connector makes it possible to transfer active ingredient from one container into another container. 1. A connector for containers containing medicinal active ingredient , comprising: a guide element having a duct designed for transferring a medicinal active ingredient and having first and second ends;', 'a piercing element arranged, at least in certain sections, in the duct and axially moveably guided within the duct by the guide element; the piercing element having first and second ends, the second end including a stop, and', 'a partition wall located proximate the first end of the guide element;', 'wherein, by connecting the first container in the first connection region, the piercing element can be moved from a starting position, in which the piercing element does not open the partition wall, into an end position, in which the first end of the piercing element opens the partition wall in order to transfer a medicinal active ingredient, and wherein the stop on the second end of the piercing element engages with the second end of the guide element to limit further movement of the piercing element., 'a first connection region for the connection of a first container, the first connection region including2. The connector as claimed in claim 1 , wherein the first end of the piercing element is sharpened or pointed and wherein the stop on the second end of the piercing element is in the form of a collar.3. The connector as claimed in claim 1 , wherein the piercing element projects by its first end facing the first connection region beyond the guide element.4. The connector as claims in claim 1 , wherein the piercing element and the guide element are designed in such a way that a clearance for transferring a medicinal active ingredient remains between an outer face of the piercing element and an inner face claim 1 , forming the duct claim 1 , or the guide element.5. The ...

Lock mechanism, equipment connector, container connector, and connection equipment

A lock mechanism includes an engaged section of a second member and an engagement member of a first member. The engagement member includes an operating section, a fulcrum section configured to contact the second member in a state in which the operating section is pressed, an engaging section engaging with the engaged section, a deformation section configured to be bent to move the engaging section when the operating section is pressed, and a fixing section fixed to the edge of a hole.

INTRADERMAL INJECTION DEVICE

Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections. Provided in some embodiments are needle-free injectors adapted to deliver intradermal injections, as well as vial adaptors that are adapted to function as spacers when used with a needle-free injection device. 119.-. (canceled)20. A needle-free injection device , comprising:a body terminating in a nozzle;a fluid reservoir housed within the body, the fluid reservoir being adapted to receive a fluid injectate;a plunger disposed within the fluid reservoir;a shaft to which the plunger is mounted such that when the shaft is driven forward, the plunger is responsively driven forward;a spring-driven propulsion system having a first spring adapted to apply force to the shaft and thus to the plunger to cause ejection of the fluid injectate through the nozzle;a lever adapted to arm the spring-driven propulsion system;a rod extending between the lever and the shaft to transmit force between the lever and the shaft via the body of the rod to compress the first spring; anda second spring in operable communication with the lever, the second spring configured to bias the lever towards a home position. This application is a divisional of U.S. patent application Ser. No. 12/824,114, filed Jun. 25, 2010, the entire content of which is incorporated herein by reference.Embodiments herein relate to the field of injections, for instance needle-free injections, and more specifically, to methods and apparatus for spring-driven intramuscular and intradermal injections.Needle-free injection systems provide an alternative to standard fluid delivery systems, which generally use a needle adapted to penetrate the outer surface of a target. Typically, needle-free injection systems are designed to eject the fluid from a fluid chamber with sufficient pressure to allow the fluid to penetrate the target ...

Apparatus for mixing and transferring medications

An apparatus for transferring a chosen quantity of medication from a vial to a container under sterile conditions is described. The present invention further facilitates dissolving solid medications contained in the vial or diluting concentrated medications contained in the vial, and transferring the resulting solutions to the container. The container may be an intravenous infuser.

Universal fluid container adapter

Various embodiments are generally directed to fluid container adapters that couple with a fluid container and enable different systems, such as endoscopic systems, to access the contents of the fluid container, such as via a tubing set. Several embodiments are particularly directed to a fluid container adapter that punctures a fluid container to couple with and gain access to the contents of the fluid container. In one embodiment, for example, a platform may be used to support a fluid container as one or more penetration members attached to a crossmember are advanced into the fluid container along rails connected between the platform and the crossmember. In such embodiments, the one or more penetration members may include lumens to enable a tubing set to access the contents of the fluid container.

COMPONENT MIXING DEVICE AND COMPONENT MIXING METHOD

The present relates to a component mixing device comprising a central unit () and a disposable cartridge, said central unit () comprising a control unit, a plurality of vial positioning elements () and a cavity for receiving said disposable cartridge, and said disposable cartridge () comprising a tubing circuitry adapted to put the components housed in said plurality of vials into communication for mixing, characterized in that the mixing device is adapted to put each vial into communication with each other through said tubing circuitry of said disposable cartridge () and mixing said components through an compressed air mechanism () located in said central unit () and controlled by said control unit. 129-. (canceled)30. A disposable cartridge to be used with a separated central unit in a component mixing device , comprising: at least two circuitry inlets each being adapted to enter in fluid communication with a vial to permit insertion of content of each vial within said circuitry,', 'at least one circuitry outlet for outputting a mixed product from the disposable cartridge and', 'a plurality of valves adapted to be controlled by a control unit of said central unit in order to create a specific path within said circuitry between said inlets and said outlet,', 'wherein said circuitry is adapted to enter in fluid communication with a pressure gradient generating mechanism of said central unit in order to generate a circuitry content driving force within it., 'a rigid microfluidic circuitry including'}31. The disposable cartridge according to claim 30 , wherein said circuitry is adapted to put at least a first vial and a second vial in fluid communication so as to mix reagent content of the first vial with reagent content of the second vial.32. The disposable cartridge according to claim 30 , further comprising at least one storing vessel for storing an intermediary product obtained through the mixing of contents of at least two vials.33. The disposable cartridge ...

ENTERAL FEEDING ADAPTERS AND METHODS OF USING THE ENTERAL FEEDING ADAPTERS

An adapter is provided for connecting a container of flowable material, such as enteral feed formula in a laminated paper container, to a feeding tube to enable bolus feeding. The adapter can transfer the flowable material from the container by piercing the container and/or a cover of the container. The adapter can form a fluid-tight friction seal on the container. In some embodiments, the adapter has a reusable tube vent long enough to be positioned in the air gap of the container when the container is inverted by a user. 1. An adapter for fluidly connecting a syringe to a container containing a composition , the syringe coupled to an enteral feeding line , the adapter comprising:a body comprising a bottom end that defines an opening and a spike;a fluid exit port extending from a top end of the body, the top end facing an opposite direction from the bottom end, the body comprising an internal chamber that fluidly connects the opening to the fluid exit port, the fluid exit port configured to direct the composition to the syringe coupled to the enteral feeding line; andone or more interface surfaces extending radially from the body, the one or more interface surfaces optionally comprising ribs configured to create a gap between the syringe and a portion of the body between the ribs when the adapter is inserted into the syringe.2. The adapter of claim 1 , wherein the bottom end comprises a wall that forms the spike and also defines at least a portion of the opening.3. The adapter of claim 1 , wherein the opening of the body lies in a plane positioned at an angle between ten degrees and eighty degrees relative to at least one of (i) a side wall of the body or (ii) a longitudinal axis of the body.4. The adapter of claim 1 , wherein the body is cylindrical.5. The adapter of claim 1 , wherein at least a portion of the body is transparent.6. A kit comprising the adapter of and further comprising at least one of (i) the container containing the composition or (ii) the ...

METHOD FOR THE PREPARATION OF A VACCINATING AGENT

A method for preparing a vaccine for immunization against the disease Disease and/or Enzootic Pneumonia in pigs in which a first container is only partly filled with a first vaccine and a second container is filled with a second vaccine, the second vaccine being transferred into the first container through an adapter device, when a closure device is penetrated for the first and/or only time, and the vaccinating agent is prepared therein, thus making the operation simple, less error-prone and more hygienic, while reducing the materials required. 2MycoplasmaCircovirus. Process according to claim 1 , wherein the first starting material comprises vaccine in amounts of more than 30% by weight claim 1 , and the second starting material comprises vaccine in amounts of more than 30% by weight.3. Process according to claim 1 , wherein said transferring of the second starting material into the first container is performed under the effect of gravity.4. Process according to claim 1 , wherein the first container is moved during and/or after the transfer of the second starting material into the first container claim 1 , so as to achieve or speed up a homogeneous reaction claim 1 , dissolving or mixing of the materials.5. Process according to claim 1 , wherein the first container is placed in or on a multiple-use injection device claim 1 , an injection gun claim 1 , a pressure injector or a self-filling syringe.6. Process according to claim 1 , wherein a kit is used for preparing the combination vaccine claim 1 , the kit comprising said first container with the first starting material claim 1 , said second container with said second starting material and the adapter device for providing a fluid connection between the first and second container claim 1 , wherein at least one of the containers is closed off with a factory-provided closure device.7. Process according to claim 1 , wherein at least one of the starting materials comprises a polymeric adjuvant or carbomer.8. Process ...

BLUNT CANNULA NEEDLE DEVICE

A needle device has a needle assembly including a hub having one end fitted with a blunt cannula. The blunt cannula has a base section, a central section and a shaft having a distal apertured end. The needle of the needle assembly extends through an internal passage of the blunt cannula and is sealingly fitted to a portion of the internal passage. The hub of the needle assembly has another end connectable to a syringe. When the device is connected to a syringe, a fluid communication path is established between the apertured end of the shaft and the interior of the syringe via the lumen of the needle. The shaft of the blunt cannula is usable to pierce the seal of a fluid store while maintaining the needle in an unused state for subsequent patient use. The distal end of the shaft may be protected by an end cap. 1. A medical device comprising: a base section adapted to couple to a needle hub;', 'a central section distally adjacent to the base section having an internal central passage;', 'a shaft extending distally from the central section, the shaft having an internal shaft passage in alignment with the central passage along a longitudinal axis to form a longitudinal passage along the blunt cannula; and, 'a blunt cannula having'}a needle assembly having a needle extending from a needle hub;wherein the longitudinal passage is configured to sealingly receive the needle from the needle assembly so that a seal fit is formed between the needle and the longitudinal passage at at least a portion thereof when the needle assembly and the blunt cannula are coupled to each other; andwherein the needle assembly with the blunt cannula coupled thereto is adapted to be attached to a syringe for use with a fluid store.2. The device of claim 1 ,wherein the shaft of the blunt cannula comprises an apertured end; andwherein the needle comprises a sharp distal end;whereby the apertured end is positioned distally from the sharp distal end when the needle is appropriately positioned within ...

Device for Transferring a Fluid Between a Storage Container and at Least One Further Container for Use

A device serves for transferring a fluid between a storage container and at least one further container for use. Said transfer device comprises a sealing section by means of which a main part of the transfer device sealingly rests on the storage container. A hollow-needle assembly comprises a hollow needle which can be moved between a retracted resting position and a deployed connecting position, the assembly, in the connecting position, providing a fluid connecting channel between the storage container and the transfer device. The hollow-needle assembly can be moved by means of a pressure actuating element. During said movement, the pressure actuating element is primarily connected to the sleeve of the hollow needle so as to be resistant to shear forces. A guiding device serves to axially guide the pressure actuating element on the main part. Said guiding device has at least one guiding pin. Said guiding pin slides in at least one associated guiding groove during movement. The guiding device is designed such that the movement of the hollow-needle assembly from the resting position to the connecting position is irreversible. In this way, the hollow needle can be moved from the resting position to the connecting position in an operationally safe manner.

Method and Apparatus for Delivering a Therapeutic Substance Through an Injection Port

Adapters for utilizing a syringe or pen injector with a subcutaneous injection port to deliver a therapeutic substance through the injection port and methods of using the adapters are provided. A syringe adapter has a body having a first end and a second end. The first end of the body is configured to receive and engage the end of a syringe so that the cannula of the syringe is held at a fixed position with the respect to the adapter. The second end of the adapter configured to mate with a mating portion of the injection port. When the second end of the adapter engages the mating portion of the injection port, the adapter assures that the cannula of the syringe is properly aligned with the subcutaneous injection port and assures that the cannula penetrates the injection port to the proper depth. Adapters for use with pen style delivery systems are also disclosed. Additionally, an adapter to facilitate loading a syringe with a therapeutic substance from a vial is disclosed.

Container for a mixing system, mixing system for parenteral nutrition, and method for mixing

Container for a mixing system being filled with liquid parenteral nutrition and comprising a male connector and a female connector. The male connector is placed on the opposite side of the container compared to the female connector and the male connector and the female connector are embodied to be mechanically engageable with each other and to engage a mechanical connection with a male connector or a female connector respectively of another container and to form a channel, which enables the passage of liquid. At least two containers form a modular system for parenteral nutrition.

CONTAINER SYSTEM

A container system having connection devices for establishing a fluid connection between the containers. In one aspect, a connection device comprises a thin point that, within its shape, has a tip between two at least substantially straight legs and wherein the other connection device has a ram with a splitting device that is designed and arranged such as to rupture said thin point by acting on the tip when the containers are coupled. In another aspect, the thin point surrounds the ram, and in a third aspect the connection devices have corresponding, similar thin points, closure elements and splitting devices. In further aspects, the connection devices are similar, and the connection devices are linearly guided. 1. Container system comprising at least two containers each forming an inner chamber ,the containers each comprising a connection device being initially closed, specifically a first connection device of a first container and a second connection device of a second container, andthe connection devices being able to be coupled together such that the coupling produces a continuous fluid connection that is closed off from the surroundings and interconnects the inner chambers of the containers such that contents that can be held in the inner chambers can be mixed,the first connection device comprising a thin point designed to rupture through the application of force by a ram of the second connection device, as a result of which the fluid connection can be established, andwherein in its shape, the thin point comprises a tip between two at least substantially straight legs and the ram comprises a splitting device that is designed and arranged such as to rupture the thin point by acting on the tip when the coupling is produced.2. Container system according to claim 1 , wherein straight claim 1 , aligned portions of the thin point adjoin different sides of the ram.3. Container system according to claim 2 , wherein the aligned portions of the thin point form a film ...

Inline liquid drug medical devices with linear displaceable sliding flow control member

Inline liquid drug medical device having a longitudinal device axis, a housing with a linear displaceable sliding flow control member displaceable along a transverse bore from a first flow control position for establishing flow communication between a first pair of ports for liquid drug reconstitution purposes to a second flow control position for establishing flow communication between a second pair of ports for liquid drug administration purposes, and a manually operated actuating mechanism for applying a linear displacement force for urging the flow control member to slide along the bore from its first flow control position to its second flow control position.

Aseptic connector and method

A method for forming an aseptic connection includes inserting an end of a sealed fill connector into a receptacle of an aseptic connector assembly; moving a pivot portion of the aseptic connector assembly relative to a body portion of the aseptic connector assembly so as to sever a portion of the fill connector, the pivot portion being at least partially disposed within the body portion; and advancing a conduit portion of the aseptic connector assembly into the fill connector so as to form an aseptic connection therebetween, the conduit portion being at least partially disposed within the pivot portion or the body portion of the aseptic connector assembly after advancing.

Pooling device for single or multiple medical containers

A device is provided for pooling a fluid from a container unit having at least one container, and includes an inlet port having at least one inlet channel configured for receiving the fluid or ambient air, and an outlet port having at least one outlet channel configured for delivering the fluid to an attachment. Both inlet and outlet ports are disposed on the device. A cavity is provided for accommodating insertion of the container unit for pooling the fluid from the at least one container. At least one spike is disposed in the cavity and configured for puncturing a stopper of the at least one container when the container unit transitions from an upper position to a lower position.

VIAL ADAPTER

An exemplary vial adapter may include a moveable member, an elongated member with a first passage, a second passage coupled to an expandable first reservoir, and a third passage coupled to an expandable second reservoir. In a first orientation of an exemplary vial adapter, a fluid may be directed through the first passage into the first reservoir or the second reservoir. In a second orientation of an exemplary vial adapter, a fluid may be drawn through the first passage and a fluid drawn through an air passage into the second passage. In a second orientation of an exemplary vial adapter, a fluid may be directed through the first passage and through the third passage into the second reservoir. In a first orientation of an exemplary vial adapter, a moveable member may be activated to direct a fluid from the second reservoir through the third passage. 1. A vial adaptor for coupling with a vial , the vial adaptor comprising:a medical connector interface, a vial interface, an expandable first reservoir, an expandable second reservoir, and a first passage extending from the medical connector interface through the vial interface; the first reservoir comprising a second passage extending through the vial interface and a first valve, wherein the first valve permits movement of a fluid into the first reservoir when the vial adaptor is in an upright orientation, and resists movement of a fluid into the first reservoir when the vial adaptor is moved toward an inverted orientation; and the second reservoir comprising a third passage extending through the vial interface.2. The vial adaptor of claim 1 , wherein the third passage is fluidly separated from the first passage.3. The vial adaptor of claim 1 , further comprising a moveable member configured to engage against the second reservoir to direct a fluid out of the second reservoir.4. The vial adaptor of claim 1 , wherein the second passage comprises a second valve.5. The vial adaptor of claim 1 , further comprising a ...

LIQUID TRANSFER DEVICES FOR USE WITH INTRAVENOUS (IV) BOTTLES

A liquid transfer device is provided having a trifurcated body that includes a vial adapter at a first end configured to telescopically mount on the crown of an IV bottle to puncture a stopper in the crown with a cannula, an IV port extending from an opposing second end of the trifurcated body, and a needleless self-sealing port extending from a third end of the trifurcated body and configured to couple with the male connector of an additive transfer device. Methods of using the liquid transfer device with an IV bottle, additive transfer device, and an infusion set to prepare an infusion liquid for administration to a patient are also provided. 1. A liquid transfer device for use with an intravenous (IV) bottle , an additive transfer device and an infusion set with an IV spike for intravenous administration of infusion liquid to a patient ,the IV bottle including a closed end IV bottle container tapering towards an open IV bottle neck and containing infusion liquid, and an IV bottle crown mounted on the IV bottle neck and having an IV bottle stopper for sealing the IV bottle,the additive transfer device having a male connector,the liquid transfer device having a longitudinal liquid transfer device centerline and comprising:a) a vial adapter having a transverse vial adapter top surface and a downward depending vial adapter skirt configured to telescopically mount on the IV bottle crown, said vial adapter having a cannula configured to puncture the IV bottle stopper for fluid communication with the IV bottle container upon mounting on the IV bottle crown,said transverse vial adapter top surface having an upright nipple oppositely directed with respect to said cannula,said nipple having a first nipple section with a first nipple section lumen in fluid communication with a cannula lumen of said cannula, andsaid nipple having a second nipple section with a second nipple section lumen in fluid communication with said cannula lumen;b) an IV port extending from said first ...

NEEDLELESS CARTRIDGE FOR AUTOMATIC DRUG COMPOUNDER

Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a needleless fluid port and a needleless vent port for fluid coupling to a vial via a vial puck. The vial puck includes corresponding needleless fluid and vent ports and a cannula. The cannula is extendible, by insertion of a protrusion on the cartridge into a shaft of the vial puck, into the vial to couple the vial to the needleless fluid and vent ports. 1. A vial puck , comprising:a recess configured to securely receive a vial including a drug;a needleless fluid port;a needleless vent port;a shaft; andan actuable cannula within the shaft, wherein, in a first position, the cannula is entirely disposed within the shaft and, in a second position, a portion of the cannula extends from the shaft into the recess.2. The vial puck of claim 1 , wherein the cannula comprises a fluid pathway and a vent pathway therewithin.3. The vial puck of claim 2 , wherein the fluid pathway is configured to fluidly couple to the needleless fluid port and the vent pathway is configured to fluidly couple to the needleless vent port when the cannula is in the second position.4. The vial puck of claim 3 , further comprising a first interior bellows within the needleless fluid port and a second interior bellows within the needleless vent port.5. The vial puck of claim 4 , wherein the first and second interior bellows are compressible to open the needleless fluid port and the needleless fluid port respectively.6. The vial puck of claim 5 , wherein the first and second interior bellows are configured to be compressible by respective first and second exterior bellows of a cartridge.7. The vial puck of claim 6 , wherein the first and second interior bellows are configured to be compressible by respective first and ...

ROTARY VALVE PUMP FOR AUTOMATIC DRUG COMPOUNDER

Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes controllable fluid pathways. One or more rotary piston pump/valves may be used to move fluid and/or gasses through the various fluid pathways of the cartridge. For example, the cartridge may include a dedicated rotary piston pump/valve for each process that moves fluid and/or gas through the cartridge. When turning, the rotary piston pump/valve acts as a pump to move the fluid or gas, and when the rotary piston pump/valve stops turning, it effectively acts as a shutoff valve, preventing any fluid flow. Magnetic couplers for the cartridge may be provided on a pump head of the compounder system. 1. A cartridge for a compounder system , the cartridge comprising:a first fluid pathway that extends from a diluent port to a vial connector; anda first rotary piston pump/valve disposed in the first fluid pathway and rotatable to control movement of a diluent from the diluent port to the vial connector, and arranged to stop rotation to prevent movement of diluent within the first fluid pathway.2. The cartridge of claim 1 , further comprising:a second fluid pathway associated with a waste port; anda second rotary piston pump/valve disposed in the second fluid pathway and rotatable to control movement of waste fluid or waste gas to the waste port, and arranged to stop rotation to prevent movement of waste fluid and waste gas within the second fluid pathway.3. The cartridge of claim 2 , further comprising:a third fluid pathway that extends from the vial connector to an output port; anda third rotary piston pump/valve disposed in the third fluid pathway and rotatable to control movement of a medication to the output port, and arranged to stop rotation to prevent movement of fluid within the third fluid pathway.4. The cartridge of claim 3 , wherein the third rotary piston pump/valve is configured to act as a shutoff valve for the output port while the first rotary piston pump/ ...

Primary Packaging for Storage and Administration of Medical and Pharmaceutical Compounds

A primary packaging for storage and/or administration of medical or pharmaceutical compounds includes a container that has a predetermined filling volume for receiving a medical or pharmaceutical compound. The container is permanently closed at a first end and has an integrally formed, circumferential flange portion at an open second end. The container has a cylindrical barrel that extends between the first end and the flange portion such that the barrel has an inner diameter and outer diameter corresponding to that of a standardized syringe for a nominal volume of the standardized syringe corresponding to the predetermined filling volume. Furthermore, a cross-sectional shape of the flange portion corresponds to the cross-sectional shape of a flange of a standardized vial. The primary packaging also includes a closure element that is adapted to fit tightly on the flange portion and into the barrel for sealing the open second end of the container. 138-. (canceled)39. A device comprising:a container with a cylindrical barrel, a permanently closed first end and an open second end, wherein a circumferential flange is integrally formed at the open second end and has an outer diameter that is larger than an outer diameter of the cylindrical barrel, and wherein the circumferential flange has a cross sectional shape that has a flat upper end surface and a flat lower end surface;a closure element that fits tightly into the open second end of the container; anda needle extraction system having a plunger rod and a cylindrical tube section, wherein a first end of the plunger rod fits into the closure element, wherein the cylindrical tube section has an inner diameter that is larger than the outer diameter of the cylindrical barrel and has a radially outwardly extending finger flange, wherein the finger flange has a radially inwardly extending projection that slides along an outer surface of the cylindrical barrel, and wherein the circumferential flange slides along an inner ...

ASEPTIC CONNECTOR

An aseptic connector assembly includes a body portion having a receptacle configured to receive a corresponding fill connector. A pivot portion is movably coupled to the body portion, the pivot portion having a channel formed therein. A conduit portion is slidably disposed within the channel formed in the pivot portion. The pivot portion has a ready position and an operative position, the pivot portion being adjustable from the ready position to the operative position via relative movement with respect to the body portion. 1. An aseptic connector assembly , comprising:a body portion having a receptacle configured to receive a corresponding fill connector;a pivot portion movably coupled to the body portion, the pivot portion having a channel formed therein; anda conduit portion slidably disposed within the channel formed in the pivot portion;wherein the pivot portion has a ready position and an operative position, the pivot portion being adjustable from the ready position to the operative position via relative movement with respect to the body portion.2. The aseptic connector assembly of claim 1 , wherein the pivot portion slides linearly relative to the body portion as the pivot portion moves between the ready position and the operative position.3. The aseptic connector assembly of claim 1 , wherein the pivot portion rotates relative to the body portion as the pivot portion moves between the ready position and the operative position.4. The aseptic connector assembly of claim 1 , further comprising:the pivot portion has a first side face and an opposing second side face with the channel extending therebetween;the conduit portion begin partially disposed within the channel so as to outwardly project from the first side face of the pivot portion; andthe body portion being disposed adjacent to the second side face of the pivot portion.5. The aseptic connector assembly of claim 1 , wherein the conduit portion is spaced apart from the receptacle when the pivot portion is ...

Apparatus, System and Method for Fluid Delivery

A filling aid. The filling aid includes a locking portion including a groove feature; and a locking feature having a locked and an unlocked position; and a filling syringe holder slidably attached to the locking portion, the filling syringe holder including a filling needle cradle portion having a tongue feature; and a needle housing portion comprising at least one tab having a starting position and a filling position, wherein the groove feature configured to accommodate the tongue feature, and wherein the locking feature interact with the filling syringe holder wherein when the locking feature moves from the locked position to the unlocked position the needle housing portion moves from the starting position to the filling position. 1. A filling aid comprising: a filling needle cradle portion having a tongue feature; and', 'a needle housing portion comprising at least one tab having a starting position and a filling position,, 'a filling syringe holder attached to a locking portion, the filling syringe holder comprisingwherein a groove feature configured to accommodate the tongue feature, andwherein the locking portion interacts with the filling syringe holder wherein when the locking portion moves from a locked position to an unlocked position the needle housing portion moves from the starting position to the filling position.2. The filling aid of claim 1 , wherein the filling needle cradle portion further comprising a frame portion whereby the frame portion maintains a filling syringe in fixed relation with the filling syringe holder.3. The filling aid of claim 1 , wherein the filling syringe holder further comprising grips.4. The filling aid of claim 3 , wherein the grips comprising gripping features.5. The filling aid of claim 1 , wherein when the locking portion attaches to a filling aid base the locking portion moves from the locked position to the unlocked position.6. The filling aid of claim 5 , wherein when the locking portion moves from the locked position ...

Adaptor for Coupling to a Medical Container

An adaptor for coupling with a medical container, including: a tubular body receiving a pierceable elastomeric piece, defining an inner cavity of the adaptor, the pierceable elastomeric piece being movable within the tubular body between a first position, in which a distal part of the pierceable elastomeric piece forms a seal of the cavity, and a second position, proximally spaced from the first position, in which the distal part opens the seal of the cavity, an air inlet, a filtering system for filling the inner cavity with decontaminated air, and a gripping member for securing the adaptor to the medical container. Also, an assembly comprising such an adaptor and a medical container. 1. A method of using an adaptor coupled with a medical container having a collar closed by a septum , said septum having an outer surface directed towards an outside of the medical container , the method comprising:providing a tubular body substantially closed at a distal end with a transversal wall provided with a central hole and substantially closed at a proximal end by a pierceable elastomeric piece, said pierceable elastomeric piece, transversal wall, and tubular body together defining an inner cavity of said adaptor, said pierceable elastomeric piece being movable within said tubular body between a first position, in which a distal part of said pierceable elastomeric piece forms a seal with said central hole, and a second position, in which said distal part is displaced from said central hole;providing an air inlet in the adaptor for allowing air from the outside to enter said inner cavity at least when said pierceable elastomeric piece moves from the first position to the second position, said air inlet comprising a filtering system for decontaminating said entering air before it reaches said inner cavity and said air inlet being in fluid communication with said central hole when said pierceable elastomeric piece is in said second position;securing the adaptor to the medical ...

Drug reconstitution system

A drug reconstitution device comprising a disposable liquid transfer unit ( 18 ) and a reusable control and drive unit ( 16 ) removably connectable to the liquid transfer unit, the liquid transfer unit including a housing ( 26 ), a docking interface ( 30 ) configured for coupling at least one of first and second constituent containers ( 2, 4 ) to the housing ( 10 ), and a pump engine ( 28 ) and fluid flow system ( 36 ) configured for transferring liquid from the first constituent container ( 2 ) to the second constituent container ( 4 ). The control and drive unit comprises a pump drive ( 22 ) configured to drive the pump engine during a liquid transfer action, the pump drive comprising a transmission output coupling ( 34 ) removably engaged with a transmission input coupling ( 50 ) of the pump engine ( 28 ) when the liquid transfer unit and control and drive unit are connected.

DRUG CONTAINER CONNECTOR AND MALE MEMBER COVER

A drug container connector () is provided with a puncture needle () capable of puncturing a plug () that seals a mouth () of a container (); and a cover () that covers an opening, on a tip side, of a flow channel () formed in the puncture needle (). The puncture needle () is configured to penetrate the cover () and puncture the plug (). The puncture needle () is provided on a connector main body (). The cover () is held by a slider (). The slider () is movable with respect to the connector main body () in a longitudinal direction of the puncture needle (). The slider () is provided with claws () capable of engaging with a flange () at the mouth of the container (). 1. A drug container connector comprising:a puncture needle capable of puncturing a plug that seals a mouth of a container; and a cover that covers an opening, on a tip side, of a flow channel through which liquid flows and that is formed in the puncture needle, the puncture needle being configured to penetrate the cover and puncture the plug,wherein the puncture needle is provided on a connector main body,the cover is held by a slider,the slider is movable with respect to the connector main body in a longitudinal direction of the puncture needle, andthe slider is provided with a claw capable of engaging with a flange at the mouth of the container.2. The drug container connector according to claim 1 ,wherein the drug container connector is configured such that a tip of the cover abuts against the plug in a state in which the claw is engaged with the flange of the container.3. The drug container connector according to claim 1 , further comprising:a lock mechanism for preventing disengagement between the claw and the flange.4. The drug container connector according to claim 3 ,wherein the lock mechanism includes: a grip arm on which the claw is formed and that can elastically bend and deform outwardly; and the connector main body for restricting bending and deformation of the grip arm.5. The drug container ...

APPARATUS AND METHODS FOR OCULAR INJECTION

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location. 118-. (canceled)19. An apparatus , comprising:a medicament container, the medicament container including triamcinolone;a housing configured to receive a portion of the medicament container;a hub configured to be coupled to the medicament container and defining a passageway through which a puncture member is disposed, the hub being fixedly coupled to the puncture member such that the hub moves with the puncture member when the puncture member is moved relative to an eye, a distal end surface of the hub having a convex surface and being configured to contact a target surface of the eye when the triamcinolone is conveyed through the puncture member; andan actuation rod at least partially disposed within the medicament container,the medicament container, the actuation rod, and the puncture member collectively configured such that (1) a portion of the actuation rod moves within the medicament container in response to a force on the actuation rod when a distal end portion of the puncture member is disposed within a suprachoroidal space of the eye, and (2) movement of a distal end portion of the actuation rod within ...

SEPTUM HOLDERS FOR USE IN SYRINGE CONNECTORS

Presented herein are embodiments of septum holders for use in syringe connectors that are used to connect syringes to other elements of liquid transfer apparatuses. The septum holders comprise a septum holder body, at least one resilient elongated arm that terminates with a distal enlarged element attached to the sides of the body, and a septum. The septum holders of the invention are characterized in that they comprise at least one bore that is created in the septum or in an insert fixed in either the body of the septum holder or in the septum that functions as the seat of a needle valve and in that the septum is attached to the bottom of the body of the septum holder projecting downwards parallel to the at least one elongated arm. 1. A septum holder comprising: a body having a disk shaped annular upper body part and a lower body part , at least one resilient elongated arm terminating with a distal enlarged element attached to the side of the body , and a septum fitted into the lower body part so that it extends downward parallel to the at least one arm;wherein the septum is made of a single piece of cylindrically shaped resilient material, the upper part of the septum has a diameter larger than the middle part of the septum in order to form a flange that rests on an annular ledge created around the inside of the bottom section of the body when the middle part of septum slides through the open center at the bottom of the bottom section and the lowest part of the septum of the septum holder has a diameter that matches that of a septum in a fluid transfer component; and, the septum comprises at least one bore created part of the way through the height of the middle part of the septum, wherein the bore functions as the seat of a needle valve and the diameter of the bore is smaller than the outer diameter of the shaft of a needle that functions as a second component of the needle valve.2. The septum holder of claim 1 , wherein the septum is held to the body by pushing ...

Liquid transfer device with dual lumen iv spike

A liquid transfer device includes a monolithic trifurcated connector body defining a barrel at a first end thereof, a single IV spike at a second end thereof and a vial adapter lumen at a third end thereof. An IV port is connected to the barrel. The single IV spike has a first IV spike lumen fluidly connected at a proximal end thereof with only the vial adapter lumen via the trifurcated connector body and a second IV spike lumen fluidly connected at a proximal end thereof with only the IV port via the trifurcated connector body, thereby separating fluid communication between the vial adapter and the single IV spike from fluid communication between the IV port and the single IV spike.

Drainage system with retention ring

In one general aspect, the present disclosure provides a drainage system. The drainage system may include a container having an interior and a mouth, the mouth having an outer surface and an opening. A frangible seal may cover the opening. A cap may be secured to the mouth, and the cap may be in fluid communication with a drainage line. The cap may have an inner surface for engaging with the outer surface of the mouth. The drainage system may further include a retention ring with a collar having an inner surface configured to engage an outer surface of the cap, where the retention ring includes a bead for at least partially concentrating a restriction force provided by the retention ring on an adjacent area of the outer surface of the cap.

DRAINAGE SYSTEM WITH RETENTION RING

In one general aspect, the present disclosure provides a drainage system. The drainage system may include a container having an interior and a mouth, the mouth having an outer surface and an opening. A frangible seal may cover the opening. A cap may be secured to the mouth, and the cap may be in fluid communication with a drainage line. The cap may have an inner surface for engaging with the outer surface of the mouth. The drainage system may further include a retention ring with a collar having an inner surface configured to engage an outer surface of the cap, where the retention ring includes a bead for at least partially concentrating a restriction force provided by the retention ring on an adjacent area of the outer surface of the cap. 1. A drainage system , the drainage system comprising:a container having an interior and a mouth, the mouth having an outer surface and an opening;a frangible seal covering the opening;a cap secured to the mouth and in fluid communication with a drainage line, the cap having an inner surface for engaging the outer surface of the mouth; anda retention ring with a collar having an inner surface configured to engage an outer surface of the cap,wherein the retention ring includes a bead for at least partially concentrating a restriction force provided by the retention ring on an adjacent area of the outer surface of the cap.2. The drainage system of claim 1 , wherein the outer surface of the mouth includes a protrusion claim 1 , and wherein the bead of the retention ring is located distally of the protrusion of the mouth.3. The drainage system of claim 1 , wherein the retention ring includes a tab extending from the collar claim 1 , the tab having a surface for receiving a removal force.4. The drainage system of claim 3 , wherein the collar of the retention ring includes a collar portion having a relatively low bending moment of inertia with respect to adjacent areas of the collar such that the collar portion deforms in response to ...

APPARATUS AND METHODS FOR OCULAR INJECTION

An apparatus includes a housing coupled to a medicament container, which is coupled to a needle. An injection assembly is disposed within the housing and includes an energy storage member and an actuation rod. A distal end portion of the actuation rod is disposed within the medicament container. The energy storage member can produce a force on a proximal end portion of the actuation rod sufficient to move the distal end portion of the actuation rod within the medicament container. This can convey at least a portion of a substance from the medicament container via the needle when a distal tip of the needle is disposed within a first region of a target location. The force is insufficient to move the distal end portion of the actuation rod within the medicament container when the distal tip of the needle is disposed within a second region of the target location. 1. An apparatus , comprising:a medicament container, the medicament container including axitinib;a housing configured to receive a portion of the medicament container;a hub configured to be coupled to the medicament container and defining a passageway through which a puncture member is disposed, the hub being fixedly coupled to the puncture member such that the hub moves with the puncture member when the puncture member is moved relative to an eye, a distal end surface of the hub being configured to contact a target surface of the eye when the axitinib is conveyed through the puncture member; andan actuation rod at least partially disposed within the medicament container, the medicament container, the actuation rod, and the puncture member collectively configured such that (1) a portion of the actuation rod moves within the medicament container in response to a force on the actuation rod when a distal end portion of the puncture member is disposed within a suprachoroidal space of the eye, and (2) movement of a distal end portion of the actuation rod within the medicament container in response to the force on ...

A DEVICE, METHOD AND KIT FOR THE RECONSTITUTION OF A SOLID OR SEMI SOLID PHARMACEUTICAL COMPOSITION

A novel device, method and kit for reconstitution of a solid or semi-solid pharmaceutical composition by a negative pressure differential includes (i) a first adapter with a first connector, a first peripheral wall wherein the first adapter is coupled to the first vial by means of a first connector; (ii) a second adapter with a second connector, a second peripheral wall wherein the second adapter is coupled to the second vial by means of a second connector; (iii) a transfer port wherein the transfer port includes a first end ending in first adapter to gain access to first vial and a second end ending in second adapter to gain access to second vial; wherein the first adapters and the second adapter are joined together in vertical direction by means of horizontal wall; wherein the adapter connected to the vials by means of the ends. 1. A novel device for reconstitution of a solid or semi-solid pharmaceutical composition by a negative pressure differential comprises:(i) a first adapter comprising a first connector, a first peripheral wall wherein the first adapter is coupled to the first vial by means of a first connector;(ii) a second adapter comprising a second connector, a second peripheral wall wherein the second adapter is coupled to the second vial by means of a second connector;(iii) a transfer port wherein the transfer port comprises a first end ending in first adapter to gain access to first vial and a second end ending in second adapter to gain access to second vial;Wherein the first adapters and the second adapter are joined together in vertical direction by means of horizontal wall;Wherein the adapter connected to the vials by means of the ends.2. The device as claimed in claim 1 , wherein the device is constructed of material selected from the group comprising of glass claim 1 , crystal claim 1 , epoxy resin claim 1 , acrylate polymer claim 1 , polyethylene terephthalate (PET or PETE) claim 1 , polycarbonate claim 1 , high-density polyethylene (HPPE) claim ...

CAP SYSTEMS WITH PIERCING MEMBER FOR PHARMACEUTICAL VIALS

A cap system for sealing injectable drugs within a vial is disclosed. The system includes an elastomeric stopper, a retainer member, a locking member, a cap assembly and a piercing member. The retainer member is arranged to snap onto the vial and the locking member slid with respect to the retainer member to permanently seal the vial. The cap assembly includes a cap and a band and is coupled to the locking member. The cap releasably holds the piercing member. The band is arranged to be removed to enable the cap to move the piercing member to penetrate the stopper, whereupon the cap can be removed. The piercing member is arranged to be connected to a syringe or other instrument to withdraw the vial's contents. 1. A cap system for a pharmaceutical vial having an interior in which a flowable material is disposed , an opening to the interior of the vial and a flanged neck surrounding the opening , the flanged neck having an undersurface , said cap system comprising:an elastomeric stopper arranged to be secured to the vial;a retainer member comprising a sidewall and a plural resilient fingers located about the periphery of said sidewall, said retainer member being arranged to be secured to the vial with said fingers of said retainer member being arranged to flex over the flanged neck of the vial and then snap into engagement with the undersurface of the flanged neck of the vial;a locking member slidably coupled to said retainer member and comprising a peripheral sidewall including inwardly projecting members, said locking member being arranged slid to a fixed position with respect to said retainer member, whereupon said inwardly projecting members of said locking member apply an inward force on said fingers of said retainer member to permanently seal said vial;a cap member coupled to said locking member, said cap member being hollow and having a socket therein; anda piercing member, said piercing member being releasably located in said socket and having a piercing tip.2. ...

Liquid-Transfer Adapter Beveled Spike

A liquid-transfer adapter operatively interposable between an injector and a vial is provided. The liquid-transfer has an injector engaging portion configured for fluidly coupling to an injector and a vial coupling. The vial coupling includes a spike that has a spike axis and a tip portion configured for piercing a septum of a vial. The tip portion includes a plurality of facets that meet each other at one or more edges and at least one of the one or more edges is sloped with respect to the spike axis. The spike defines a channel extending therethrough in fluid communication with the injector engaging portion. A channel opening is defined in at least one of the facets and disposed without interrupting the edges. 1. A liquid-transfer adapter operatively interposable between an injector and a vial , comprising:an injector engaging portion configured for fluidly coupling to an injector; anda vial coupling including a spike that has a spike axis and a tip portion configured for piercing a septum of a vial, the tip portion including plurality of facets that meet each other at one or more edges, at least one of the one or more edges being sloped with respect to the spike axis, the spike defining a channel extending therethrough in fluid communication with the injector engaging portion and including a channel opening defined in at least one of the facets and disposed without interrupting the edges.2. The liquid-transfer adapter of claim 1 , wherein the edges comprise junctions between the facets.3. The liquid-transfer adapter of claim 1 , wherein the edges comprise cutting surfaces configured for cutting the septum as the spike is pushed therethrough.4. The liquid-transfer adapter of claim 1 , wherein the tip portion comprises at least three facets.5. The liquid-transfer adapter of claim 4 , wherein the channel opening comprises a channel opening disposed in each of at least three of the facets.6. The liquid-transfer adapter of further comprising a seal disposed at the ...

Method And Assembly For Fluid Transfer And Drug Containment In An Infusion System

A fluid transfer assembly, drug container, and method for enabling fluid transfer in an infusion system is taught. The assembly includes a fluid container containing an infusion fluid, and a drug container. The fluid container has at least one inlet port for receiving a medical substance from the drug container. The assembly further includes at least one fluid barrier controlling fluid passage between the drug container and the fluid container. The inlet port exhibits a first luer-lock connector, and the drug a container is sealed by a cap exhibiting a second luer-lock connector for attachment to the first luer-lock connector. The fluid barrier is designed and arranged to be ruptured by an external force to allow the fluid passage. 149-. (canceled)50. A drug container for use in an infusion system , said drug container comprising: a fixed dose of a medical substance , and a cap for sealing said drug container , said cap further comprising a luer-lock connector for attachment to a corresponding connector provided on an inlet port of a container for infusion fluid , thereby creating a luer-lock coupling , said cap further comprising a protruding member forming a fluid duct between said drug container and said luer connector.51. The drug container according to claim 50 , wherein said luer-lock connector is attached directly to said cap.52. The drug container according to claim 50 , wherein said luer-lock connector is integral with said cap.53. The drug container according to claim 50 , further comprising a removable closure for protecting said luer-lock connector.54. The drug container according to claim 50 , further comprising a pierceable closure for protecting said luer-lock connector.55. The drug container according to claim 50 , said drug container further comprising a neck claim 50 , and said cap further comprising a protruding member able to be attached to said neck by an annular capsule member.56. The drug container according to claim 50 , said drug container ...

Double Chamber Device for Point of Use Mixing

Disclosed is a double chamber container. The first chamber comprises a stopper coupled to a first end and a cover coupled to a second end. The second chamber comprises a plunger coupled to one end and an open second end. The first chamber is coupled to the second chamber such that the first end of the first chamber is coupled to the second end of the second chamber.

CONNECTION EQUIPMENT AND EQUIPMENT CONNECTOR

Connection equipment includes an equipment connector comprising a first connecting section, a first liquid flow path that communicates with a equipment, and a first valve that is to open and close the first liquid flow path, a container connector comprising a second connecting section, a second liquid flow path that communicates with the container, and a second valve that is to open and close the second liquid flow path, and a lock mechanism that locks the equipment connector and the container connector in a state where the first liquid flow path is in communication with the second liquid flow path, and that unlocks the connectors in a state where the first valve and the second valve are closed. 1. Connection equipment comprising:an equipment connector comprising a first connecting section that is connectable to equipment through which a fluid moves, a first liquid flow path that communicates with an interior of the equipment when the equipment is connected to the first connecting section, and a first valve that is to open and close the first liquid flow path and that opens when pressed,a container connector comprising a second connecting section that is connectable to a container, a second liquid flow path that communicates with an interior of the container when the container is connected to the second connecting section, and a second valve that is to open and close the second liquid flow path and that opens when pressed by the first valve, anda lock mechanism that locks the equipment connector and the container connector in a state where the first valve is pressed by the second valve, the first valve and the second valve are opened and the first liquid flow path is in communication with the second liquid flow path, and that unlocks the connectors in a state where the first valve and the second valve are closed.2. The connection equipment according to claim 1 , wherein the equipment connector comprises a pressure adjustment section claim 1 , and a first gas flow ...

Medical Connecting Device

A bottle connector for use in a medical fluid transfer arrangement, the bottle connector having an axial direction and a radial direction and comprising a first part and a second part, the first part comprising a hollow piercing member comprising an inner gas channel and extending in the axial direction beyond the end of the first part. The second part comprises a bottle coupling member, for coupling the bottle connector to a medical bottle. The first and second parts are pre-connected and are concentrically arranged with respect to each other and the bottle connector has a transport configuration with a first, maximum length in which the piercing member is completely located within the bottle connector, and a fluid transfer configuration with a second, minimum length. 1. A bottle connector for use in a medical fluid transfer arrangement , said bottle connector having an axial direction and a radial direction and comprising:a first generally cylindrical part having a first end a second end, said first generally cylindrical part comprising a hollow piercing member comprising an inner channel, said hollow piercing member extending in said axial direction from an interior portion of said first generally cylindrical part beyond said second end of said first generally cylindrical part; anda second generally cylindrical part connected to the first generally cylindrical part, said second generally cylindrical part having a first end and a second end, said second generally cylindrical part comprising a bottle coupling member, for coupling said bottle connector to a medical bottle,wherein the second generally cylindrical part is releasably locked to the first generally cylindrical part and is transitionable between a transport configuration and a fluid transfer configuration, wherein the second generally cylindrical part is configured to move from an unlocked configuration corresponding to the first and second generally cylindrical parts not being locked together, to the ...

Medical Device Connector

The present invention relates to a medical device connector for connecting a piercing device, with a vial comprising a base member. A plurality of grip members, each grip member comprising a distal end (D) and a proximal end (P) and each comprising a wedge portion adapted to temporarily or permanently lock the medical device connector to the vial. The base member further comprises a plurality of flanges, wherein the proximal ends (P) of the grip members are arranged to the flanges. The flanges extend substantially out from the periphery of the base member in a direction substantially perpendicular to the direction of the grip members, wherein the space formed between the flanges of the base member forms at least one grip portion. The present invention provides for a medical device connector which is easy and comfortable to use, which provide good stacking capabilities and which permits a user to readily acknowledge that the medical device connector is correctly assembled with the vial. 115-. (canceled)16. A medical device connector comprising;a base member having a through going aperture;a plurality of grip members, each grip member comprising a distal end and a proximal end and each comprising a wedge portion adapted to temporarily or permanently keep the medical device connector to a vial;wherein the base member comprises a plurality of flanges, wherein the proximal ends of the grip members are arranged on the plurality of flanges, the plurality of flanges extend out from a periphery of the base member in a direction perpendicular to a longitudinal direction of the grip members, wherein a plurality of spaces formed between the plurality of flanges of the base member form a plurality of grip portions, each the flange of the base member comprises two grip members and bridge sections extend between the grip members of separate flanges.17. The medical device connector of claim 16 , further comprising a first connection site and a second connection site connected by ...

SYSTEMS AND METHODS FOR DELIVERY OF PERITONEAL DIALYSIS (PD) SOLUTIONS WITH INTEGRATED INTER-CHAMBER DIFFUSER

The invention provides, in some aspects, a container system for medical solutions such as peritoneal dialysis (PD) solutions. The invention particularly features a system which includes a first compartment that contains a first medical solution, e.g., a PD osmotic agent, and a second compartment that contains a second medical solution, e.g., a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. To that end, a container system can include a diffuser that is disposed in a fluid pathway between the first and second compartments, e.g., to facilitate homogeneous mixing of the first and second PD agents. That diffuser is disposed within and moves relative to a structure, such as a port that defines the fluid pathway between those compartment. Thus, for example, the diffuser can comprise a body that “floats” within that pathway-defining structure and that moves from one end to the other (and/or to from points there between), depending on a direction of solution flow through the structure. 1. A container system for medical solutions , comprisingA. a first compartment that contains a first medical solution,B. a second compartment that contains a second medical solution, the second compartment being fluidly couplable with the first compartment via a fluid pathway-defining structure (hereinafter, “port”),C. a diffuser that is disposed within and movable relative to the port.227-. (canceled)28. A container system for medical agents , comprisingA. a first compartment that contains a first medical agent,B. a second compartment that contains a second medical agent, the second compartment being fluidly couplable with the first compartment via a fluid pathway- ...

ENTERAL NUTRITION CONTAINER CAP AND METHODS OF MAKING AND USING THE CAP

A package closure system may include a package outlet including a first connection element and a cap configured to removably connect to the package outlet using the first connection element and comprising a second connection element. An overcap can be configured to removably connect to the cap using the second connection element. A method for providing a nutritional composition from a container to an enteral line may include: removing an overcap from a cap, the cap is configured to direct a nutritional composition through a channel within the cap, the cap removably connected to the container; connecting the cap sealingly to the enteral line; and applying a pressure to the container to direct the nutritional composition from the container through the channel and into the enteral line.

Drug Transfer Adapter

A drug transfer adapter includes a body having a first end and a second end positioned opposite the first end, a transfer spike extending from the body and defining an opening, with the transfer spike configured to pierce a closure of a container, a connector extending from the body, and a securing member extending from the body. The securing member has a first side and a second side positioned opposite the first side, with the first side of the securing member including an adhesive surface configured to secure the body to a container. 1. A drug transfer adapter comprising:a body having a first end and a second end positioned opposite the first end;a transfer spike extending from the body and defining an opening, the transfer spike configured to pierce a closure of a container;a connector extending from the body; anda securing member extending from the body, the securing member having a first side and a second side positioned opposite the first side, wherein the first side of the securing member comprises an adhesive surface configured to secure the body to a container.2. The drug transfer adapter of claim 1 , wherein the securing member comprises an extension portion extending from the body claim 1 , a tapered portion extending from the extension portion claim 1 , and a rectangular portion extending from the tapered portion.3. The drug transfer adapter of claim 2 , wherein the rectangular portion is wider than the extension portion.4. The drug transfer adapter of claim 1 , wherein the securing member is flexible.5. The drug transfer adapter of claim 1 , wherein the transfer spike extends from the first end of the body.6. The drug transfer adapter of claim 5 , wherein the connector extends from the second end of the body.7. The drug transfer adapter of claim 1 , wherein the body is rectangular claim 1 , the body including a first grip surface and a second grip surface positioned opposite the first grip surface.8. The drug transfer adapter of claim 7 , wherein the ...

Medication dosing systems and methods

A method of preparing liquid medication doses using an automated dosing device may include securing a vial within a vial holder. The vial includes a liquid medicament. An empty syringe is secured within a syringe holder with a plunger of the syringe being secured by a plunger gripper and a luer lock of the syringe within a luer lock gripper. The syringe holder and the vial holder are moved closer together to insert a needle of the syringe through a septum of the vial while longitudinal axes of the syringe and the vial are at a downward angle and while the vial holder is lower than the syringe holder. The syringe holder and the vial holder are rotated to vertically align the longitudinal axes with the vial holder above the syringe holder. The plunger gripper is pulled away from the luer lock gripper to transfer liquid medicament into the syringe.

RECONSTITUTION DEVICE, SYSTEM, AND METHOD TO ADMINISTER A DRUG IN A MODERATE BOLUS

A reconstitution device includes: a piercing member having a first end and a second end, the first end of the piercing member configured to engage an administration port; a delivery member having a first end and a second end, the first end of the delivery member configured to engage a delivery site; a collar configured to engage a vial; and a cap extending from the collar and holding the piercing member and the delivery member such that the second end of the piercing member and the second end of the delivery member are disposed within the cylindrical collar. 1. A reconstitution device comprising:a piercing member having a first end and a second end, the first end of the piercing member configured to engage an administration port;a delivery member having a first end and a second end, the first end of the delivery member configured to engage a delivery site;a collar configured to engage a vial; anda cap extending from the collar and holding the piercing member and the delivery member such that the second end of the piercing member and the second end of the delivery member are disposed within the collar.2. The reconstitution device of claim 1 , wherein the cap is formed integrally with the collar.3. The reconstitution device of claim 1 , wherein the collar is cylindrical and is configured to concentrically engage the vial.4. The reconstitution device of claim 1 , wherein the collar engages with the vial claim 1 , such that the piercing member is in fluid communication with the vial and the delivery member is in fluid communication with the vial.5. The reconstitution device of claim 1 , wherein the administration port is an intravenous (“IV”) bag port claim 1 , and wherein the first end of the piercing member is configured to pierce the IV bag port.6. The reconstitution device of claim 1 , wherein the delivery site is an IV line claim 1 , connectable to a patient claim 1 , and wherein the first end of the delivery member is configured to connect to the IV line.7. The ...

MODULAR DOSING ASSEMBLY OF MEDICAL SUBSTANCES

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient. 1. A vessel for intermixing a beneficial substance , comprising:a vessel having a plurality of engagement mechanisms, wherein the engagement mechanisms are configured to engage a plurality of containers housing a beneficial sub stance.2. The vessel of claim 1 , wherein the vessel is a container.3. The vessel of claim 2 , wherein the plurality of engagement mechanisms abut the container.4. The vessel of claim 2 , wherein the plurality of engagement mechanisms abut a wall of the container.5. The vessel of claim 2 , where a plurality of the engagement mechanisms are surface mounted or flush mounted to the container.6. The vessel of claim 1 , wherein the vessel is a bag.7. The vessel of claim 6 , wherein the plurality of engagement mechanisms abut the bag.8. The vessel of claim 6 , wherein the plurality of engagement mechanisms abut a wall of the bag.9. The vessel of claim 6 , where a plurality of the engagement mechanisms are surface mounted or flush mounted to the bag.10. The vessel of claim 1 , wherein the vessel is a bottle.11. The vessel of claim 10 , wherein the plurality of engagement mechanisms abut the bottle.12. The vessel of claim 10 , wherein the plurality of engagement ...

MODULAR DOSING ASSEMBLY OF MEDICAL SUBSTANCES

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient. 1. A bottle for intermixing beneficial substances , comprising:a bottle having at least two entry ports and at least one exit port, the at least two entry ports configured to receive at least two containers.2. The bottle of claim 1 , wherein the at least two entry ports abut the bottle.3. The bottle of claim 1 , wherein the at least two entry ports abut a wall of the bottle.4. The bottle of claim 1 , wherein the at least two entry ports are surface mounted to the bottle.5. The bottle of claim 1 , wherein the at least two entry ports are surface mounted to a wall of the bottle.6. The bottle of claim 1 , wherein the at least two entry ports are flush mounted to the bottle.7. The bottle of claim 1 , wherein the at least two entry ports are flush mounted to a wall of the bottle.8. The bottle of claim 1 , wherein the at least two entry ports are configured to directly receive the at least two containers.9. The bottle of claim 1 , wherein the at least two entry ports are configured to directly receive and engage the at least two containers.10. The bottle of claim 1 , wherein the at least two containers abut the bottle upon engagement to the bottle.11. The bottle of claim 1 , wherein the at ...

MODULAR DOSING ASSEMBLY OF MEDICAL SUBSTANCES

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient. 1. A syringe for intermixing beneficial substances , comprising:a syringe having at least two entry ports and at least one exit port, the at least two entry ports configured to receive at least two containers.2. The syringe of claim 1 , wherein the at least two entry ports abut the syringe.3. The syringe of claim 1 , wherein the at least two entry ports abut a wall of the syringe.4. The syringe of claim 1 , wherein the at least two entry ports are surface mounted to the syringe.5. The syringe of claim 1 , wherein the at least two entry ports are surface mounted to a wall of the syringe.6. The syringe of claim 1 , wherein the at least two entry ports are flush mounted to the syringe.7. The syringe of claim 1 , wherein the at least two entry ports are flush mounted to a wall of the syringe.8. The syringe of claim 1 , wherein the at least two entry ports are configured to directly receive the at least two containers.9. The syringe of claim 1 , wherein the at least two entry ports are configured to directly receive and engage the at least two containers.10. The syringe of claim 1 , wherein the at least two containers abut the syringe upon engagement to the bag.11. The syringe of claim 1 ...

Syringe Adaptor and Complementary Fluid-Port Adaptor

A syringe adaptor includes a body, shaped to define a body lumen, a syringe fitting at a proximal end of the body, configured to connect to a distal end of a syringe, a needle extending distally from the syringe fitting into the body lumen, a septum housing, and an elastomeric septum mounted inside the septum housing. The septum includes a proximal face, shaped to define an aperture having an aperture diameter, and a distal face. The septum is shaped to define a cavity, joined to the aperture, having a cavity diameter that is larger than the aperture diameter. The septum housing is configured to slide proximally within the body lumen such that a distal end of the needle contained in the cavity passes through the distal face of the septum. Other embodiments are also described.

Modular dosing assembly of medical substances

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient.

Modular dosing assembly of medical substances

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient.

CAROUSEL FOR AUTOMATIC DRUG COMPOUNDER

A carousel configured to house a plurality of pump cartridges for a compounder system is provided. The carousel may include a plurality of cartridge pockets each having an extended portion that covers a portion of a cartridge and a bottom surface Shaving an extension with a recess. The bottom surface recess of each cartridge pocket may be shaped and sized to receive a needle housing of a pump cartridge in the cartridge pocket. A recess may be provided in the extended portion of each pocket that receives a protrusion that extends from a top surface of a backpack coupled to the pump cartridge to secure the pump cartridge in the cartridge pocket. The bottom surface recess may have an additional bottom surface that prevents actuation of the needle housing of the pump cartridge. 1. A method , comprising:providing a carousel having a plurality of cartridge pockets disposed about a periphery of the carousel;providing a cartridge and backpack assembly in each cartridge pocket of the carousel; andproviding the carousel having the cartridge and backpack assemblies onto a carousel hub of a compounder system.2. The method of claim 1 , further comprising retrieving a selected one of the cartridge and backpack assemblies from the carousel by extending a bayonet of a pump drive mechanism of the compounder system into an opening in the selected cartridge and backpack assembly and rotating the bayonet.3. The method of claim 2 , wherein rotating the bayonet comprises rotating a portion of the bayonet against a ramp structure disposed on a surface of an opening in a pump cartridge of the selected cartridge and backpack assembly to lift and pull the selected cartridge and backpack assembly from the carousel.4. The method of claim 3 , wherein rotating the bayonet further comprises rotating an additional portion of the bayonet against a deformable structure disposed between the pump cartridge and a backpack of the selected cartridge and backpack assembly and wherein rotating the ...

Connector for a medical package containing a liquid

The invention relates to a connector for a medical package containing a liquid. The connector comprises a lower section which has a connecting piece for a container of said medical package and a passageway which is closed by a septum, as well as an upper section which is provided with a cap that covers the septum and can be broken off, said septum having, on a top side, a plurality of connections in the form of elevations, for a spike and/or for a needle.

Device, Sealing Member and Fluid Container

A device for transferring a fluid to and/or from a fluid container having a sealing member. The device includes a piercing member for penetrating the sealing member and an elongated body defining a longitudinal flow channel through which a fluid may flow into and/or out of the fluid container and at least one opening that communicates with the flow channel. The at least one opening is arranged to extend along at least 1% of the length (l) of the piercing member to ensure that at least part of the at least one opening is located substantially adjacent to the innermost side of a sealing member when the device is in use. 110-. (canceled)11. A device for transferring a fluid to or from a fluid container having a sealing member , the device comprising:a piercing member having a tip for penetrating the sealing member;an elongated body defining a longitudinal flow channel through which a fluid may flow into and/or out of the fluid container, the elongated body having a greater width than the width of the piercing member;at least one opening that communicates with the flow channel, the at least one opening being arranged to extend along at least 20% of the length (l) of the piercing member such that at least part of the at least one opening is located substantially adjacent to an innermost side of said sealing member;an retractable sleeve arranged to at least partly cover and seal the at least one opening when the device has not been inserted into said sealing member of said fluid container, wherein said sleeve is arranged to abut against an outermost side of said sealing member when the device has been inserted into said sealing member of said fluid container and be retracted as the piercing member penetrates more deeply into said sealing member such that the retractable sleeve will cover and seal only a portion of the at least one opening which are located outwards of the outermost side of the sealing member when the device is in use and thus prevent any fluid from ...

Cassette assembly for syringe fill system

A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for “push-pull”, “pull-push”, “push-push”, and “pull-pull” modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single-use components of the syringe fill system.

CONNECTOR SYSTEM COMPRISING AT LEAST TWO WITHDRAWAL PORTS

A connector system for connecting a withdrawal device to a container for a medical fluid, in particular for a rinsing solution, comprising a first withdrawal port and a second withdrawal port which are each designed for a withdrawal of the medical fluid from the container, wherein the first withdrawal port and the second withdrawal port are designed differently and each is sealed by a resealable membrane and a break-away cap. 115-. (canceled)16. A connector system for attaching a withdrawal device to a container for a medical liquid , said connector system comprising a first withdrawal port and a second withdrawal port , which are each designed for withdrawing the medical liquid from the container , the first withdrawal port and the second withdrawal port being of different designs and each being closed by a reclosable membrane and a break-off cap.17. The connector system as claimed in claim 16 , wherein the first withdrawal port and the second withdrawal port are designed to receive a withdrawal device with in each case different flow rates and/or different attachments.18. The connector system as claimed in claim 16 , wherein the first withdrawal port is designed to receive a first withdrawal device with a cylinder attachment claim 16 , and/or in that the second withdrawal port is designed to receive a second withdrawal device with a spike attachment.19. The connector system as claimed in claim 16 , wherein the first withdrawal port has an outer thread and can be connected to the first withdrawal device by means of the cylinder attachment of the first withdrawal device being screwed on claim 16 , and a fluid connection can be produced by opening the membrane claim 16 , and/or in that the second withdrawal port can be connected to the second withdrawal device by means of the spike attachment of the second withdrawal device being pushed into the membrane of the second withdrawal port claim 16 , and a fluid connection can be produced by opening the membrane.20. The ...

FILLING NEEDLE FOR FILLING A CONTAINER WITH A FLUID

A filling needle for filling a container with a fluid, in particular a pharmaceutical or cosmetic fluid, having a housing that extends along a longitudinal axis and has an inlet opening and an outlet opening, having a core element arranged within the housing so as to be displaceable between an opening position and a closure position, having a plunger element coupled to the core element that closes and opens the outlet opening, and having an actuating arrangement for the displacement of the core element between the opening position and the closure position. The core element has at least one core magnet, wherein the actuating arrangement is arranged outside the housing and has at least one actuating magnet, and wherein core actuating magnets are arranged such that they interact with an attractive action and the core element and the actuating arrangement are displaceable jointly parallel to the longitudinal axis. 1. A filling needle for filling a container with a fluid , having a housing , wherein the housing extends along a longitudinal axis and has an inlet opening and an outlet opening , having a core element which is arranged within the housing so as to be displaceable parallel to the longitudinal axis between an opening position and a closure position , having a plunger element which is coupled to the core element , wherein the plunger element closes the outlet opening in the closure position and opens up the outlet opening in the opening position , and having an actuating arrangement for the displacement of the core element between the opening position and the closure position , wherein the core element has at least one core magnet in the form of a permanent magnet , wherein the actuating arrangement is arranged outside the housing and has at least one actuating magnet in the form of a permanent magnet , and wherein the at least one core magnet and the at least one actuating magnet are arranged such that they interact with an attractive action and the core ...

Haptic feedback and audible output syringe

A syringe fill system is described, which is useful for filling syringes for dental anesthetic applications. The system incorporates capability for “push-pull”, “pull-push”, “push-push”, and “pull-pull” modes of operation, for loading syringes with compositions comprising multiple fluid components. A syringe fillable by such syringe fill systems is described, providing haptic and audible feedback to a user, to aid in administering precise amounts of therapeutic compositions. Also disclosed are cassette assemblies for use in such syringe fill systems. Such cassette assemblies may be formed of plastic and elastomeric materials of construction, as disposable or single-use components of the syringe fill system.

NEEDLE VALVE AND CONNECTORS FOR USE IN LIQUID TRANSFER APPARATUSES

The invention is a needle valve and connectors for use in liquid transfer apparatuses. The needle valve of the invention is not the conventional type of needle valve known in the art that comprises a threaded valve stem, which allows very accurate control of the flow through the valve, and that uses elastic materials, such as rubber, as a sealing component. The needle valve of the invention comprises two components: the first component is a hollow needle having a smooth exterior surface and a port at the side of the cylindrical shaft, the second component is a seat made of rigid material e.g. plastic with low friction properties. 2. The needle valve of claim 1 , wherein the seat is made of plastic with low friction properties.3. The needle valve of claim 2 , wherein the plastic with low friction properties is acetal plastic.4. The needle valve of claim 1 , comprising a lubricant for reducing the friction between the needle and the seat.6. The connector of claim 5 , wherein the port at the distal end of needle that allows exchange of fluid between the surroundings and the hollow interior of said needle is completely blocked by the interior of the bore in seat of the needle valve when said connector is not connected to a second fluid transfer component.8. The fluid transfer apparatus of claim 7 , wherein the ports at the distal ends of both the first needle and the second needle are located in the seat of needle valve and are fully sealed by the bores in which they are located thereby isolating the interiors of said first needle and said second needle from each other when the distal end of the connector section is not attached to any other fluid transfer component.9. The fluid transfer apparatus of claim 7 , wherein the ports at the distal ends of both the first needle and the second needle are located in the seat of needle valve and are open thereby allowing fluid communication between the interiors of said first needle and said second needle when the distal end of ...

FLUID TRANSFER DEVICES AND METHODS OF USE

Some embodiments disclosed herein related to a device for transferring precise amounts of fluid from at least one source container to a at least one target container. In some embodiments, the fluid is first transferred from the source container (e.g., a vial) through a connector to an intermediate measuring container (e.g., a syringe). In some embodiments air can pass through an air inlet and enter the vial to compensate for the volume of fluid withdrawn from the vial. An air check valve or a bag or a filter can prevent the fluid from escaping through the air inlet. The precisely measured amount of fluid can then be transferred from the intermediate measuring container to the target container (e.g., an IV bag). In some embodiments the connector can include a source check valve and a target check valve to direct fluid first from the source container to the intermediate measuring container and then from the intermediate measuring container to the target container. Some embodiments of the device can include a motor and a controller for automatically actuating a plunger of the syringe to transfer the desired amount of fluid. 1. A medical fluid transfer system for the transfer of medical fluids between different medical fluid containers , the medical fluid transfer system comprising: send one or more fluid transfer instructions comprising instruction to transfer a fluid between a source container and a target container, and', 'receive one or more results of a fluid transfer process; and, 'a remote management device being configured to a syringe interface being configured to couple to the fluid transfer module,', 'a syringe pump being configured to engage at least a portion of the fluid transfer module, the syringe pump being further configured to transfer the fluid between the source container and the target container through the fluid transfer module, and', receive the one or more fluid transfer instructions from the remote management device via the communication ...

SYRINGE DEVICE FOR COMMUNICATING TWO TYPES OF SUBSTANCES TO EACH OTHER AND METHOD THEREOF

To realize creation of a state in which two types of substances are communicated to each other via the double-ended needle assembly by a one-step continuous push operation and reduce a probability of entry of air or liquid leakage at that time. A syringe device includes an administration holder , and a cylinder portion which allows insertion of the administration holder . The cylinder portion includes a coupling holder , a slit holder coupled to the coupling holder , and a double-ended needle assembly disposed slidably in an interior of the coupling holder . A cartridge for a freeze-dry product is mounted in the administration holder , and a cartridge for solvent is mounted in the coupling holder . When the administration holder is pushed, the double-ended needle assembly slides. When one of the needle points unseals the cartridge for freeze-dry product, the other needle point of the double-ended needle assembly lightly prick the cartridge for the solvent, and the other needle point unseals the cartridge for solvent by a further sliding movement of the double-ended needle assembly 121.-. (canceled)22. A syringe device comprising:an administration holder including a first storage chamber, the first storage chamber including a first cartridge mounted therein, the first cartridge being configured to store a first substance and having a sealing member formed at a front end portion thereof;a hollow cylinder portion; anda double-ended needle assembly including a first needle point and a second needle point, whereinthe cylinder portion includes:a holder sliding portion configured to slidably retain the administration holder inserted at least partly from one end of the cylinder portion;a second storage chamber provided on the other end side of the cylinder portion, the second storage chamber including a second cartridge mounted therein, the second cartridge being configured to store a second substance and having a sealing member formed at a front end portion thereof; anda ...

HERMETIC CLOSING PLUG FOR A SEALED STERILE VIAL CONTAINING MEDICAL OR NUTRITIONAL ACTIVE SUBSTANCES, SUITABLE FOR THE STERILE CONNECTION TO A CONTAINER OF LIQUID DILUENT SOLUTION, AND STERILE CONNECTION SYSTEM USING SAID CLOSING PLUG

A closing plug for a sealed sterile vial containing medical or nutritional active substances, which is suitable for the sterile connection to a container of liquid diluent solution. There is also described a sterile connection system between a sealed sterile vial closed by means of a plug and a tube for drawing said active substances, for mixing them with a liquid diluent solution inside a sterile container. The plug requires an internal sterile chamber in which, upon the piercing of an outer film for sealing the plug, a compressible protection cap of a piercing tip of the tube is inserted, which abuts against a seat of the sterile chamber allowing the tip to pierce the end wall of the protection cap and then the inner membrane of the closing plug. An intermediate pierceable membrane placed on the seat of the internal chamber of the vial may be included. 2. The sterile connection system according to claim 1 , wherein said closing plug of the vial comprises a further internal or intermediate pierceable membrane placed on said seat of the internal chamber of the plug.3. The sterile connection system according to claim 1 , wherein said closing plug is in thermoplastic material.4. The sterile connection system according to claim 3 , wherein said internal pierceable membrane is in one piece with the plug.5. The sterile connection system according to claim 1 , wherein said outer sealing film or membrane of the closing plug is in medical paper claim 1 , thermoplastic material claim 1 , rubber claim 1 , silicone claim 1 , thin aluminum or other suitable easily pierceable material claim 1 , eventually in one piece with the closing plug.6. The sterile connection system according to claim 1 , wherein said protection cap of the piercing to of the drawing and mixing tube is in rubber o silicone or other suitable material with pierceable end wall claim 1 ,7. The sterile connection system according to claim 2 , wherein said further internal or intermediate pierceable membrane is ...

Variable Rate Dispenser With Aseptic Spike Connector Assembly

A dispenser includes a container with an endwall and a cap covering the endwall. The cap has an aperture and a first film covering the aperture. A hood over the cap has a barrel defining a bore which is coaxially aligned with the aperture, a second film sealing the bore, and a gasket compressed behind the second film. A spike is carried for movement in the barrel between retracted and advanced positions. The dispenser has first and second conditions. In the first condition, the first and second films are against each other and seal the aperture and barrel, and in the second condition, the first and second films are away, unsealing the aperture and the barrel. When the dispenser is in the second condition and the spike moves from the retracted position to the advanced position, the spike pierces the endwall.

Pressure Equalizing Device and Receptacle

Provided is a pressure equalizing device for facilitating drug reconstitution in a closed system. The pressure equalizing device includes a container for attachment to a receptacle, to permit pressure equalization between the container and the receptacle. The container includes a first chamber and a second chamber. The device further includes a vent channel extending between the first chamber and a distal opening of the vent channel. In accordance with the invention, when the receptacle is connected to the pressure equalizing device, the vent channel establishes direct fluid communication between the first chamber and the receptacle. Additionally, a longitudinal axis of the pressure equalizing device is configured to be aligned with or parallel to a longitudinal axis of the receptacle when the pressure equalizing device is attached to the receptacle. 1. A pressure equalizing device comprising:a container for attachment to a receptacle, to permit pressure equalization between the container and the receptacle, the container comprising a first chamber, a second chamber, and a bellows disposed within the container between the first chamber and the second chamber;a fluid transfer member connected to and extending from the container; anda vent channel defined by the fluid transfer member, the vent channel extending between the first chamber and a distal opening of the vent channel and the second chamber is disposed between the bellows and a distal end of the vent channel,wherein when the receptacle is connected to the pressure equalizing device, the vent channel establishes direct fluid communication between the first chamber and the receptacle,wherein a longitudinal axis of the pressure equalizing device is configured to be aligned with or parallel to a longitudinal axis of the receptacle when the pressure equalizing device is attached to the receptacle, andwherein expansion or contraction of the bellows modifies a volume of the first chamber.2. The pressure equalizing ...

Transport and Transfer Container for a Liquid Medium

A production method for producing a transport and transfer receptacle for at least one fluid medium, for example, for at least one sterile liquid is proposed. The method comprises supplying at least one container for receiving the fluid medium. At least one energy unit is supplied. The energy unit effects—for example, complete—emptying of the fluid medium from the container when the transport and transfer receptacle is used. The fluid medium is introduced into the container and the container is closed. The fluid medium is charged with positive pressure, for example, using the energy unit. The positive pressure is maintained until the fluid medium is removed. Furthermore, a transport and transfer receptacle which can be produced according to the production method and which has at least one packaging is proposed. 1. A production method for producing a transport and transfer receptacle for at least one fluid medium , wherein the method comprising:supplying at least one container for receiving the fluid medium;supplying at least one energy unit, wherein the energy unit effects the emptying of the fluid medium from the container when the transport and transfer receptacle is used;introducing the fluid medium into the container and closing the container;charging the fluid medium with positive pressure using the energy unit, wherein the positive pressure is maintained until the fluid medium is removed; andpacking at least the container in the state charged with positive pressure in at least one packaging.2. The production method according to claim 1 , wherein at least one gas bubble is produced in the container during the introduction of the fluid medium and wherein the charging of the fluid medium is carried out in such a manner that the gas bubble completely disappears after a waiting period resulting in a transport and transfer receptacle which is free from gas bubbles.3. The production method according to claim 2 , wherein the waiting period is at least one hour.4. The ...

SYSTEMS AND METHODS FOR FLUID DELIVERY

The invention provides for a delivery system including a delivery assembly configured to allow delivery of a single dose of a therapeutic agent (e.g., vaccine, drug, medicament, etc.) from a Blow-Fill-Seal (BFS) vial to a patient. The delivery assembly generally includes a modular design consisting of separately constructed components cooperatively arranged and coupled to one another. The modular construction allows for rapid manufacturing reconfigurations of one or more components with minimal costs to create new delivery assembly configurations that meet specific needs (i.e., different modes of delivery depending on agent to be delivered, such as subcutaneous, intramuscular, intradermal, intravenous injection, spray, or droplet delivery). The delivery assembly is generally configured to be filled on-site and in the field and is further capable of delivery of the agent in a controlled manner and without requiring specialized skill in administering delivery of such agent. 1. A delivery system for delivery of a fluid agent , the delivery system comprising:a blow-fill-seal (BFS) vial containing a single dose of a fluid agent; and a hub member having a proximal end defining an inlet port and a distal end defining an outlet port and a channel providing a fluid pathway from said inlet port to said outlet port, said inlet port having a connection fitting configured to receive and retain a corresponding connection fitting of the BFS vial thereto, said inlet port configured to receive the fluid agent from the BFS vial;', 'a one-way valve positioned within said fluid pathway of said channel, said one-way valve configured to limit fluid flow to an antegrade direction from said inlet port toward said outlet port;', 'an insert member positioned within said fluid pathway of said channel and adjacent to said outlet port of said hub member, said insert member having a channel in alignment with said fluid pathway; and', 'an administration member for administering said fluid agent ...

VIAL CLOSURE FOR REHYDRATING MEDICATION

A vial cap is configured to releasably contain a portion of a material, for example a powdered medication, for dispensing into a container. Via operation of a depressable plunger, the material is released into the container for rehydrating and mixing with a liquid, and thereafter may be extracted, such as via a needle. In this manner, a rehydrated medication may be provided in a predetermined amount and at a desired time. 1. A cap for a container holding a liquid , the cap comprising:a cap body comprising a durable material, the cap body configured with a space for containing an anhydrous material;a depressable plunger coupled to the cap body, the depressable plunger having an extended portion to release the anhydrous material into the liquid when the depressable plunger is depressed;a flexible o-ring operable as a seal for the depressable plunger; anda septum disposed at least partially within the depressable plunger, the septum operable to permit a needle to pass therethrough to access the liquid.2. The cap of claim 1 , wherein the o-ring and the septum are monolithic.3. The cap of claim 1 , wherein the depressable plunger is protected from accidental activation by being at least partially contained within the cap body.4. The cap of claim 1 , further comprising a releasable agitator disposed in the space for containing the anhydrous material.5. The cap of claim 1 , wherein the anhydrous material is a medication that must be administered intravenously.6. The cap of claim 1 , wherein the depressable plunger comprises a heel that forces a portion of a membrane into an opened position claim 1 , and wherein the membrane at least partially surrounds the anhydrous material.7. The cap of claim 1 , wherein the depressable plunger locks into a depressed position after being depressed.8. A method for rehydrating a powdered medication in preparation for intravenous injection claim 1 , the method comprising:coupling a vial cap containing the powdered medication to a vial ...

A SEPTUM HOLDER WITH MOVEABLE SEPTUM

Disclosed is a septum holder that comprises a body having an upper body part and a lower body part that has a bored out interior. An insert comprising at least one bore that forms the seat of a needle valve fits loosely into the bored out interior of the lower body part. A septum comprising an upper part is attached to an exterior surface of the lower body part of the septum holder. A lower part of the septum extends downward beyond the lower edge of the lower body part of the septum holder. The septum holder is characterized in that the insert can freely move up and down in the interior of the lower body part and the septum can freely move up and down on the exterior surface of the lower body part. Also disclosed is a connector section for a liquid transfer apparatus that comprises the septum holder. 1. A septum holder comprising: a body having an upper body part and a lower body part , the lower body part comprising a bored out interior; an insert comprising at least one bore that forms the seat of a needle valve , the insert fitted loosely into the bored out interior of the lower body part; and , a septum comprising an upper part attached to an exterior surface of the lower body part of the septum holder and a lower part of the septum that extends downward beyond the lower edge of the lower body part of the septum holder;wherein the insert can freely move up and down in the interior of the lower body part and the septum can freely move up and down on the exterior surface of the lower body part.2. A septum holder according to claim 1 , wherein the body comprises a disk shaped annular upper body part with at least one resilient elongated arm terminating with a distal enlarged element attached to the side of the upper body part.3. A septum holder according to claim 2 , wherein the body comprises a lower body part comprised of a cylindrically shaped annular section that projects downward from the upper part parallel to the at least one arm.4. A septum holder ...

VIAL ADAPTOR AND FLUID TRANSFER SYSTEM

A vial adaptor comprises first and second housings coupled to each other, a sheath enclosing the first and second housings, and a spike disposed in the first and second housings. The first and second housings form a first chamber therein. The sheath and the first and second housings form therebetween a second chamber in air communication with the first chamber. The second housing is slidable relative to the first housing to cause the spike piercing through a front stopper to establish air and fluid communication with a vial attached to the vial adaptor, meanwhile to vary the volume of the first chamber and press the air into the second chamber. Upon a fluid being drawn from the vial, the air in the first and second chambers enters the vial to compensate the pressure reduction caused by the fluid drawn out to prevent fluid spillage or aerosolizing from the vial. 1. A vial adaptor comprising:a first housing;a second housing movably coupled to the first housing, the first housing and the second housing form a first chamber therein;a spike disposed in the first housing and the second housing, the spike having:a tip positioned adjacent to a front end of the first housing,a fluid port connected to a back end of the second housing,a first fluid channel opening at the tip and connected to the fluid port, anda second fluid channel opening at the tip and connected to the first chamber;a sheath surrounding the first housing and the second housing to form a second chamber between the sheath and an external surface of the first housing and the second housing,wherein the second chamber is in air communication with the first chamber, andwherein displacement of the second housing toward the first housing advances the tip of the spike to protrude out of the first housing and vary a volume of the first chamber.2. The vial adaptor of claim 1 , wherein the first housing is a first sleeve and the second housing is a second sleeve telescopically coupled to the first sleeve claim 1 , the ...

PRESSURE-REGULATING VIAL ADAPTORS

In certain embodiments, a vial adaptor comprises a housing configured to couple the adaptor with a vial, an access channel, a regulator channel, and a regulator assembly. The access channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. The regulator channel is configured to facilitate a flow of a regulating fluid from the regulator assembly to compensate for changes in volume of a medical fluid in the vial. In some embodiments, the regulator assembly includes a flexible member configured to expand and contract in accordance with changes in the volume of the medical fluid in the vial. In some embodiments, the flexible member is substantially free to expand and contract. In some embodiments, the flexible member is not partly or completely located in a rigid enclosure. 1. (canceled)2. A vial adaptor configured to couple with a sealed vial , the vial adaptor comprising:a housing assembly comprising a piercing member capable of piercing a septum of a sealed vial when the piercing member is urged against the septum of the vial along an insertion axis;an extractor channel, wherein the extractor channel extends between a proximal extractor aperture and a distal extractor aperture and is configured to permit withdrawal of fluid from the sealed vial when the vial adaptor is coupled to the sealed vial, and wherein at least a portion of the extractor channel passes through at least a portion the housing assembly;a regulator channel, wherein the regulator channel extends between a proximal regulator aperture and a distal regulator aperture, and wherein at least a portion of the regulator channel passes through at least a portion of the housing assembly; anda valve in the regulator channel, the valve configured to transition between a closed configuration and an opened configuration in response to rotation of the vial adaptor about an axis of rotation between an upright position and an upside down position, wherein the axis ...

System and Method for Containing and Dispensing Fluids

An integral injection molded strip () of a single plastic material is provided, the strip comprising a plurality of vials () connected by frangible (breakable) connecting members (). Each vial (as molded as part of the integral injection molded strip) has a neck portion () with an internal delivery passage () and a squeezable body portion (), the squeezable body portion having an internal chamber () for holding a single dose of a fluid product (), the chamber () having an open top end () fluidly connected to the internal delivery passage () in the neck portion, and the chamber having a bottom end () adapted for filling with the fluid product. The internal delivery passage () (of the neck portion) has an open bottom end () fluidly connecting to the body chamber, an opposing open top end (), and an integral injection molded internal membrane () (formed in the delivery channel during injection molding of the integral strip of vials) that seals the delivery passage () prior to being pierced by a needle () of a dispensing device (). 1. An integral injection molded strip made of a single plastic material and comprising a plurality of single-use vials , each vial adapted to be assembled to a needle or another dispensing device for delivery of a single dose of a fluid product from the vial by squeezing the vial itself ,each single-use vial comprising an injection molded integral neck portion and a flexible body portion of the single plastic material, the flexible body portion having an internal chamber for holding a single dose of the fluid product and flexible body wall adapted for squeezing the fluid product out an open top end of the chamber into an open delivery passage in the neck portion, the delivery passage having an open bottom end in fluid communication with the internal chamber for receiving the fluid product and an opposing open top end for delivery of the fluid product out the top end of the vial,an injection molded internal membrane within the delivery passage ...

Pre-filled diluent syringe vial adapter

In some embodiments, an adapter comprises an adapter body comprising a coupling member configured for coupling with a pre-fillable assembly and a spike having at least one conduit extending from a central body. At least one conduit extends through the spike, adapter body and the coupling member. A spike cover is sized to receive and seal the spike, the cover reversibly securable to the central body and receiving members configured to receive a vial shroud.

Binary Connector for Drug Reconstitution

A connector is configured to connect a drug container with a solution container and permit contents of the drug container to be combined with the solution container. The connector has a connector body with a first coupling for fluid connection with the drug container. The first coupling defines a first fluid passage. The connector body also has a second coupling for fluid connection with the solution container. The second coupling defines a second fluid passage. A control valve has a movable valve body that defines a third fluid passage. The valve body is positionable relative to the connector body in a first position, in which the first fluid passage is sealed from the second fluid passage. The valve body is also positionable in a second position, in which the first fluid passage is connected in fluid communication with the second fluid passage by the third fluid passage.