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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 19629. Отображено 100.

05-01-2012 дата публикации

Hemostatic fibrous material

Номер: US20120004636A1

Автор: Denny Lo

Принадлежит: Denny Lo

This disclosure relates to devices for promoting the clotting of blood in human beings or animals, or hemostatic devices. These devices may comprise a fibrous material or materials comprising one or more fibers such as a gauze or a cloth. Some of the fibers in these materials or devices may comprise a macromolecular material and a hemostatic hemostatic additive material such as kaolin or another clay.

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Номер записи: 1

12-01-2012 дата публикации

Blood coagulation inducing polymer hydrogel

Номер: US20120009242A1

Автор: Adam Behrens, Bartley P. Griffith, Brendan J. Casey, Peter Kofinas, Trevor A. Snyder

Принадлежит: University of Maryland at Baltimore, UNIVERSITY OF MARYLAND AT COLLEGE PARK

The present application is drawn to a synthetic, polymer hydrogel-based material, which is able to actively induce the body's natural hemostatic coagulation process in blood or acellular plasma. The present invention provides the development of a primary amine containing polymer hydrogel capable of inducing blood coagulation and delivering therapeutics for hemostatic or wound care applications, and a method of forming such a primary amine containing polymer hydrogel capable of inducing the blood coagulation process. The primary amine containing polymer hydrogel is able to achieve the same end result as biological-based hemostatics, without the innate risk of disease transmission or immunological response, and at a fraction of the price. Furthermore, due to its inherent hydrogel-based design the material has the capability of arresting blood loss while simultaneously delivering therapeutics in a controlled manner, potentially revolutionizing the way in which wounds are treated.

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Номер записи: 2

02-02-2012 дата публикации

Spray-Dried Blood Products and Methods of Making Same

Номер: US20120027867A1

Автор: Joseph A. Dacorta, Michael Lawrence Galiger, Thomas H. Fischer

Принадлежит: Entegrion Inc

The present invention is directed to a method of preparing dehydrated blood products, comprising the steps of: (a) providing a hydrated blood product; (b) spray-drying the hydrated blood product to produce a dehydrated blood product, as well as dehydrated blood products made by the method. The present invention is directed to a method of treating a patient suffering from a blood-related disorder, comprising the steps of: (a) rehydrating a therapeutic amount of the dehydrated blood products to produce a rehydrated therapeutic composition; and (b) administering the rehydrated therapeutic composition to the patient. The present invention is directed to a bandage or surgical aid comprising the dehydrated blood products described above.

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Номер записи: 3

08-03-2012 дата публикации

Deodorizing Compositions

Номер: US20120058074A1

Автор: Thomas Daniel, Volker Braig

Принадлежит: BASF SE

The present invention relates to odor-inhibiting compositions comprising water-absorbing polymer particles and at least one oxidase.

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Номер записи: 4

08-03-2012 дата публикации

Activated leukocyte composition and uses for wound healing

Номер: US20120058156A1

Автор: Adi Zuloff-Shani, Eilat Bain, Eilat Shinar, Irene Ginis, Marina Bubis, Mitchell Shirvan, Orit Frenkel

Принадлежит: Macrocure Ltd

Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds.

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Номер записи: 5

22-03-2012 дата публикации

Water-absorbing resin composition

Номер: US20120070484A1

Автор: Takayasu Taniguchi, Tatsuya Oida, Yasuhiro Nawata

Принадлежит: Individual

A water-absorbent resin composition having an antimicrobial property, which suppresses the generation of dust of the antimicrobial agent. A water-absorbent resin composition comprising a water-absorbent resin and an antimicrobial agent comprising an inorganic compound carrying an antimicrobial metal, the water-absorbent resin composition being characterized in that the degree of generated dust of the water-absorbent resin composition is at most 100 CPM. The water-absorbent resin composition of the present invention can be suitably used as hygienic materials such as disposable diaper, sanitary napkin and incontinence pad; urine-absorbent materials for pets; materials for civil engineering and construction such as packing materials; drip absorbents; food freshness retaining materials such as cold-reserving agents; horticultural articles such as water-retaining materials for soils; and the like.

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Номер записи: 6

29-03-2012 дата публикации

Hydrophilic polyproylene melt additives

Номер: US20120077886A1

Автор: Matthew T. Scholz, Michael R. Berrigan, Thomas P. Klun

Принадлежит: 3M Innovative Properties Co

Melt additive ionic and non-ionic surfactants to impart stable durable hydrophilicity to thermoplastic polymers or blends thereof.

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Номер записи: 7

29-03-2012 дата публикации

Absorbent foam wound dressing materials

Номер: US20120078154A1

Автор: Michelle Del Bono, Paul Howard Lowing, William Pigg

Принадлежит: Systagenix Wound Management US Inc

A wound dressing material comprising a solid substrate having interstitial spaces therein, wherein said substrate is a hydrophilic open-cell foam material, and wherein said interstitial spaces are at least partially filled by a hydrophilic polyurethane foam different from said substrate foam material. Also provided is a method of making a porous wound dressing material comprising the steps of: providing a substrate of a solid hydrophilic first foam material; applying a fluid or gel polyurethane foam prepolymer mixture to at least one surface of said solid substrate; and curing said prepolymer in contact with said solid substrate.

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Номер записи: 8

05-04-2012 дата публикации

Antimicrobial adhesive system

Номер: US20120083536A1

Автор: David D. Cox, Leland W. Annett, Robert E. Lund

Принадлежит: Individual

An adhesive composition having dispersed therein a broad spectrum antimicrobial agent for use in medical applications, such as an adhesive for surgical drapes, wound dressings and tapes, is provided. The adhesive is composed of acrylic polymers, tackifiers and a preferred antimicrobial agent, diiodomethyl-p-tolylsulfone. The subject adhesive composition may be formulated as either an essentially solventless hot melt, or as a solvent based system wherein an emulsion of the antimicrobial agent and the removal of excess solvent is avoided.

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Номер записи: 9

12-04-2012 дата публикации

Antimicrobial foam

Номер: US20120087966A1

Автор: Jan Frances HAVILAND

Принадлежит: OBE Goods LLC

A resilient foam material having an active antimicrobial bound to, incorporated within, and projecting from its surface is provided for incapacitating or destroying microbes. The antimicrobial has an atomic structure that is capable of mechanically piercing or lysing a microbe thereby incapacitating or destroying the microbe. The resilient antimicrobial foam material may be manufactured into a resilient antimicrobial foam product for drawing across a surface and mechanically incapacitating or destroying microbes on the surface. The resilient antimicrobial foam material may be manufactured into a membrane for providing a sterile barrier for a surface. The resilient antimicrobial foam material is manufactured by combining the antimicrobial with a foam polymer material, heating the foam polymer material under pressure to a temperate that does not deactivate the antimicrobial, incorporating a blowing agent, cooling the material, and extruding the material.

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Номер записи: 10

12-04-2012 дата публикации

Absorbent article

Номер: US20120089106A1

Автор: Shinpei Komatsu, Toshiyuki Tanio, Yuki Noda

Принадлежит: Unicharm Corp

An absorbent article includes a topsheet having a contact surface in contact with the skin of a wearer; a liquid-impermeable backsheet through which a liquid does not pass; and an absorber provided between the topsheet and the backsheet, a cooling sensation material including a refresher agent in the topsheet or between the topsheet and the backsheet. On the outside of the planar direction of the topsheet from the contact region in which an excretion unit of the wearer is in contact in the topsheet, there is a region having a greater amount of the cooling sensation material per unit area than the amount of the cooling sensation material per unit area in the contact region.

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Номер записи: 11

03-05-2012 дата публикации

Polymers and Hydrogels

Номер: US20120107369A1

Автор: Adrian S. Fox, Guoming Sun, Roy R. Yeoman, III

Принадлежит: nanoDERM LLC

Methods and compositions related polymers and hydrogels. In some cases to biodegradable hydrogels for use in medical applications are disclosed. The polymers and hydrogels may be produced from cross-linked dextran and poly(epoxides). The poly(epoxides) may be poloxamers.

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Номер записи: 12

10-05-2012 дата публикации

Method

Номер: US20120116281A1

Автор: Stephen Cotton

Принадлежит: Brightwake Ltd

A method of manufacturing a wound dressing or the like comprises the steps of a) providing a layer of substrate material; b) extruding a curable hydrophobic gel precursor composition onto that substrate material via one or more mobile applicators; and c) causing or allowing the hydrophobic gel precursor composition to cure to form a hydrophobic gel. Wound dressings or the like that can be manufactured by such a method comprise a layer of substrate material, the wound facing surface of which carries bands of hydrophobic gel that are intermingled in a lattice-like arrangement.

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Номер записи: 13

17-05-2012 дата публикации

Multiamino Acid-Based Poly(Ester Amide)s

Номер: US20120123064A1

Автор: Chih-Chang Chu, Mingxiao Deng

Принадлежит: CORNELL UNIVERSITY

Biodegradable saturated and unsaturated polyester amides (PEA)s made from multiamino acid monomers and methods of making biodegradable saturated and unsaturated PEAs.

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Номер записи: 14

24-05-2012 дата публикации

Clay-based hemostatic agents and devices for the delivery thereof

Номер: US20120130296A1

Автор: Daniel J. Burns, Denny Lo, Francis X. Hursey, Giacomo Basadonna, Raymond J. Huey

Принадлежит: Z Medica LLC

A hemostatic device for promoting the dotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

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Номер записи: 15

31-05-2012 дата публикации

Topical Gels and Methods of Using the Same

Номер: US20120134951A1

Автор: Nathan Stasko, Pranav R. Joshi, Susanne Bauman

Принадлежит: Individual

Provided according to some embodiments of the invention are topical gels that may release nitric oxide. Also provided are methods of using such topical gels in the treatment of wounds and other skin ailments. The topical gels comprise diazeniutndiolate-functionalized polysiloxane macromolecules.

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Номер записи: 16

31-05-2012 дата публикации

Wound dressing materials

Номер: US20120135062A1

Автор: Lorraine Nisbet

Принадлежит: Systagenix Wound Management US Inc

A wound dressing material comprising: a wound dressing carrier, N-acetyl cysteine or a salt or derivative thereof, and a stabilized ascorbate. Suitably, the stabilized ascorbate comprises an ascorbate-2-polyphosphate. Also provided are wound dressing comprising the materials, methods of treatment with the materials, and methods of making the materials.

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Номер записи: 17

31-05-2012 дата публикации

Wound pad comprising a body of compressed open-celled foam material

Номер: US20120136328A1

Автор: Eva-Karin Daun, Magnus Paledzki, Ulf Johannison

Принадлежит: Molnycke Health Care AB

An absorbent article, such as a wound pad, comprising a body of compressed thermoplastic or thermo-set open-celled foam is described, wherein the body has a pattern of ultrasonically made depressions in two opposite sides thereof, the depressions in the opposite sides being coaxial to each other and separated from each other by a common bottom portion which is compressed to a higher extent than the remaining parts of said body. A method for manufacturing such a body is also described.

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Номер записи: 18

07-06-2012 дата публикации

Umbilical cord amniotic membrane products

Номер: US20120141595A1

Автор: Amy Tseng, Ek Kia Tan, Scheffer Tseng

Принадлежит: TissueTech Inc

Disclosed herein, in certain instances, are tissue grafts derived from UCAM. Further disclosed herein, in certain instances, are use for tissue grafts derived from UCAM.

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Номер записи: 19

14-06-2012 дата публикации

Solid dressing for treating wounded tissue

Номер: US20120150087A1

Автор: Dawson Beall, Martin Macphee

Принадлежит: Dawson Beall, MACPHEE Martin

Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of a fibrinogen component and thrombin, wherein the thrombin is present in an amount between 0.250 Units/mg of fibrinogen component and 0.062 Units/mg of fibrinogen component. Also disclosed are methods for treating wounded tissue.

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Номер записи: 20

21-06-2012 дата публикации

Absorbent article having releasable odor control

Номер: US20120157805A1

Автор: Magali Pourcel, Mariangela Caputi

Принадлежит: Procter and Gamble Co

An absorbent article comprises a topsheet, a backsheet, an absorbent core disposed between the topsheet and backsheet, and a cyclodextrin complex comprising cyclodextrin and at least three components complexed with the cyclodextrin. The absorbent article has a Total Headspace Area at Time 0 Minutes of no greater than about 0.50×10 8 , a Total Headspace Area at Time 30 Minutes of at least about 1.00×10 8 , and a Total Headspace Area at Time 240 Minutes of at least about 2.70×10 8 , as measured by the Headspace Test Method.

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Номер записи: 21

05-07-2012 дата публикации

Electrospun silk material systems for wound healing

Номер: US20120171256A1

Автор: David L. Kaplan, Scott E. Wharram, Stephen McCarthy, Xiaohui Zhang

Принадлежит: TUFTS UNIVERSITY, University of Massachusetts Foundation Inc

The present invention relates to the processes of preparing silkfibroin/polyethylene oxide blended materials, and the resulting materials thereof, which are suitable for biomedical applications such as wound healing. In particular, the electrospun silk fibroin/PEO mats with a silk:PEO blend ratio of 2:1 to 4:1, treated with controlled evaporation, constraint-drying techniques, and/or alcohol treatment, and/or PEO extraction, demonstrate suitable physical and biofunctional properties, such as fiber structure, topography, absorption, water vapor transmission rates, oxygen permeation, and biodegradability, relevant to biomaterial systems with utility for wound dressings.

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Номер записи: 22

05-07-2012 дата публикации

Antimicrobial raw material and method for manufacturing the same, and antimicrobial material

Номер: US20120171406A1

Автор: Hiroshi Mase, Koji Hirota

Принадлежит: Mitsui Chemicals Inc

Provided is an antimicrobial raw material having excellent antibacterial and corrosion-resistance properties, which can be directly formed as a film even on a plastic substrate with low heat-resistance or a substrate whereof the color or properties are likely to change due to heat, and this can be achieved at relatively low cost. The antimicrobial raw material is a laminated structure which comprises a substrate layer and a copper-tin alloy layer disposed on the substrate layer, and which has a thickness ranging from 5 nm to 200 nm. The substrate layer is made of resin, natural fiber, or paper, the resin having the deflection temperature under load being 115° C. or lower when measured in accordance with ASTM-D648-56 under a load of 1820 kPa. The copper-tin alloy layer contains over 60 at % but no more than 90 at % of copper and 10 at % or more but less than 40 at % of tin.

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Номер записи: 23

19-07-2012 дата публикации

Particulate water absorbent and process for production thereof

Номер: US20120184670A1

Автор: Hiroko Ueda, Katsuyuki Wada, Koji Honda, Kozo Nogi, Masato Abe, Motohiro Imura, Taishi Kobayashi, Taku Iwamura, Yoshiro Mitsukami

Принадлежит: NIPPON SHOKUBAI CO LTD

A particulate water absorbing agent of the present invention is a water absorbing agent containing a water absorbing resin as a main component, the particulate water absorbing agent containing a polyvalent metal cation and satisfying: (1) the polyvalent metal cation is contained in an amount between 0.001 wt % and 5 wt % relative to the amount of the water absorbing agent; (2) an absorbency without pressure (CRC) is not less than 28 (g/g) and an absorbency against pressure (AAP 4.83 kPa) is not less than 10 (g/g); (3) the absorbency against pressure and the absorbency without pressure satisfy 77≦AAP (4.83 kPa)+1.8×CRC≦100; and (4) a moisture content of the water absorbing agent is between 5 wt % and 20 wt %. This provides a water absorbing agent which has blocking resistance after moisture absorption, is excellent in stability to shock and suppresses Re-Wet when used in a diaper.

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Номер записи: 24

16-08-2012 дата публикации

Absorbent Articles with Tear Resistant Film

Номер: US20120209230A1

Автор: Todd Leon Mansfield

Принадлежит: Procter and Gamble Co

A disposable absorbent article that includes an elastic film material. The elastic film resists the growth of a tear and include an SEEPS block copolymer having a T m of between about 10° C. and about 20° C. The film has a time-to-fail of greater than 1 hour.

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Номер записи: 25

30-08-2012 дата публикации

Tampons including mositure-activated compositions

Номер: US20120220970A1

Автор: Jeffery Richard Seidling, Jeremy David Paulsen, Scott W. Wenzel, Thomas W. Van Den Bogart

Принадлежит: Kimberly Clark Worldwide Inc

The present disclosure is directed to alleviating the uncomfortable and unpleasant sensations that may accompany insertion and removal of personal care devices. Specifically, the present disclosure is directed to a personal care device that includes a moisture-activated composition that becomes lubricious only upon contact with moisture, such as from mucosal surfaces in the body.

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Номер записи: 26

06-09-2012 дата публикации

Product for the management of inflammations, pressure sores and/or oral sores (aphthas) as well as the use of such product

Номер: US20120225111A1

Автор: Gert Hartmut Scholz

Принадлежит: Lohmann and Rauscher GmbH and Co KG

The invention relates to a product for the management of inflammations, pressure sores and/or oral sores (aphthas) which is made predominantly, and preferably completely, from a bioresorbable material, with the bioresorbable material exhibiting a flexible and/or compressible pad element which adheres to the mucosa, and in particular being designed completely as a pad element.

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Номер записи: 27

27-09-2012 дата публикации

Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds

Номер: US20120245540A1

Автор: Dmitry Zimnitsky, Jenny Finkbiner

Принадлежит: Individual

According to an illustrative embodiment a method to promote healing of a wound is provided comprising contacting the wound with a biologically active composition comprising a lipoic acid derivative and gelatin. In another embodiment a topical composition is provided, which can be formulated as a homogenous mixture, such as a spray, mist, aerosol, lotion, cream, solution, oil, gel, ointment, paste, emulsion or suspension or applied on a carrier material, such as a bandage, gauze, foam, sponge, hydrogel, hydrocolloid, hydrofiber, occlusive dressing, adhesive composition or scaffold. Methods for producing such a topical composition and carrier material with the topical composition applied thereto are also disclosed.

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Номер записи: 28

11-10-2012 дата публикации

Transdermal therapeutic systems containing 4-n-butylresorcinol

Номер: US20120259020A1

Автор: Cathrin Scherner, Karl-Heinz Woeller, Ludger Kolbe, Rainer Wolber

Принадлежит: Beiersdorf AG

Transdermal therapeutic systems that contain 4-n-butylresorcinol as an active ingredient.

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Номер записи: 29

01-11-2012 дата публикации

Absorbent material

Номер: US20120276183A1

Автор: Colin Bradford

Принадлежит: Individual

An absorbent product intended particularly for use as a wound dressing comprises an admixture of carboxymethyl chitosan and chitosan wherein the chitosan incorporates at least one antimicrobial agent. Absorbency is provided by the carboxymethyl chitosan and antimicrobial properties by the antimicrobial agent incorporated in the chitosan.

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Номер записи: 30

08-11-2012 дата публикации

Wound Dressings Containing Complexes of Transition Metals and Alginate for Elastase-Sequestering

Номер: US20120282321A1

Автор: Kelman I. Cohen, Yousef Mohajer

Принадлежит: Individual

Transition metal (e.g., silver and copper) derivatized phosphorylated polysaccharides (cellulose, starch, gauze) provide antimicrobial and elastase sequestration properties to wound dressings, and the wound dressing have enhanced water sorption and elastase sequestration when used with alginates. Wound dressings with alginates (e.g., silver alginate, crosslinked alginates, etc.) provide enhanced wound fluid absorption as well as elastase sequestration.

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Номер записи: 31

22-11-2012 дата публикации

Wound dressing

Номер: US20120294927A1

Автор: Marius-Thomas Gorka

Принадлежит: Lohmann and Rauscher GmbH and Co KG

The invention relates to a sterile wound dressing having a backing and a nonabsorbent elastomer wound contact layer, wherein the elastomer matrix is formed by a synthetic three-block elastomer, preferably a copolymer of polystyrene block and polyolefin block (SEPS, SEBS, SEEPS, etc.) or mixtures thereof, wherein the total polymer content is less than 3.2 wt %, in particular 3.0 wt % or less, preferably 2.6 wt % or less, and is plasticized by an apolar oil and/or petroleum jelly.

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Номер записи: 32

22-11-2012 дата публикации

Tape having pattern of adhesive layers

Номер: US20120295054A1

Автор: John A. HOPE

Принадлежит: PERFORMTEX PRODUCTS LLC

An adhesive tape includes a base material and a plurality of adhesive layers disposed on a first side of the base material. A plurality of exposed base material areas separate the plurality of adhesive layers, such that when the adhesive tape is viewed from the first side, the plurality of exposed base material areas appear to be a plurality of intersecting lines.

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Номер записи: 33

29-11-2012 дата публикации

Absorbent article comprising a composite material

Номер: US20120302440A1

Автор: Charlotta Hanson, Fredrik Wernersson, Hans Theliander, Harald Brelid, Ingrid Gustafson, Kristoffer Lund, Torgny Falk

Принадлежит: SCA HYGIENE PRODUCTS AB

An absorbent article including a freeze dried composite material. The freeze dried composite material includes cellulosic pulp (e.g. CTMP) and an absorbent material. The absorbent material includes microfibrillated cellulose (MFC) with a specified content of carboxylate groups.

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Номер записи: 34

20-12-2012 дата публикации

Clay-based hemostatic agents and devices for the delivery thereof

Номер: US20120321691A1

Автор: Daniel J. Burns, Denny Lo, Francis X. Hursey, Giacomo Basadonna, Raymond J. Huey

Принадлежит: Z Medica LLC

A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

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Номер записи: 35

03-01-2013 дата публикации

Nanoporous Membrane Responsive to Electrical Stimulation and Method for Manufacturing the Same

Номер: US20130006180A1

Автор: Gumhye Jeon, Jin Kon Kim, Jinseok Byun, Seung Yun Yang

Принадлежит: Academy Industry Foundation of POSTECH

The present invention relates to a nanoporous membrane for flux control in response to electrical stimulation. The nanoporous membrane includes a supporting layer with a plurality of pores; and an electrically responsive layer that is connected to around the entrances of the pores and undergoes a volume change by oxidation or reduction caused by electrical stimulation to thereby lead to a change in pore size.

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Номер записи: 36

10-01-2013 дата публикации

Antimicrobial Textiles Comprising Peroxide

Номер: US20130011491A1

Автор: Albina Mikhaylova, Bernd Liesenfeld, Gerald M. Olderman, Susan Leander, William Toreki

Принадлежит: Quick Med Technologies Inc

This invention pertains to method for imparting a durable antimicrobial activity to substrates, particularly textiles. An acetate-free metal and peroxide antimicrobial treatment formulation is prepared by adjusting the pH of a mixture of a metal salt in aqueous hydrogen peroxide to about 7.5. The substrate is treated with the composition and dried to afford the treated substrate with antimicrobial activity. Zinc salts, ions, or complexes are preferred.

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Номер записи: 37

31-01-2013 дата публикации

Hemostatic sponge

Номер: US20130028975A1

Автор: Hans Christian Hedrich, Joris Hoefinghoff

Принадлежит: Baxter Healthcare SA, Baxter International Inc

The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that—said polymeric component is coated onto a surface of said matrix of a biomaterial, or—said matrix is impregnated with said polymeric material, or—both.

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Номер записи: 38

14-02-2013 дата публикации

Perfume Compositions

Номер: US20130039876A1

Автор: Alan Forbes Provan, David Jonathan Bradshaw, John Martin Behan, Keith Douglas Perring, Michael Gordon Evans

Принадлежит: Givaudan Nederland Services BV

Perfume compositions comprise between 10% and 30% in total weight of perfume ingredients selected from two groups, Group A, Group B, with the provisos that over 5% but less than 15% of the perfume composition must comprise Group A ingredients, and for compositions comprising less than 10% of Group A ingredients in the aggregate percentage of Group B ingredients present must be at least equal to the expression (2*/10−A %) where A % is the total percentage of Group A ingredients in the composition.

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Номер записи: 39

14-02-2013 дата публикации

Silk-Based Ionomeric Compositions

Номер: US20130039986A1

Автор: David L. Kaplan, Monica A. Serban

Принадлежит: TUFTS UNIVERSITY

Disclosed herein are pH-dependent silk fibroin-based ionomeric compositions and colloids, and methods of making the same. The state of the silk fibroin ionomeric compositions is reversible and can transform from a gel-like colloid to a more fluid-like solution, or vice versa, upon an environmental stimulus, e.g., pH. Thus, the silk-based ionomeric compositions and colloids can be applied in various industries, ranging from electronic applications to biomedical applications, such as sensors, gel diodes, absorbent materials, drug delivery systems, tissue implants and contrast agents.

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Номер записи: 40

14-02-2013 дата публикации

Devices and methods for the delivery of blood clotting materials to bleeding wounds

Номер: US20130041332A1

Автор: Jeffrey L. Horn, Raymond J. Huey

Принадлежит: Z Medica LLC

An apparatus for promoting the clotting of blood and controlling bleeding comprises a receptacle for retaining blood clotting material in particulate form therein. A pad for controlling bleeding comprises a mesh structure and a support attached to the mesh structure to facilitate the application of pressure to the pad and the wound. A bandage applicable to a bleeding wound comprises a mesh structure and a flexible substrate attached to the mesh structure, the substrate being a cloth or plastic member that may be adhesively attachable to cover a wound. In any embodiment, at least a portion of the receptacle or mesh structure is defined by a mesh having openings therein, and at least a portion of the particulate blood clotting material is in direct contact with blood. The mesh may include a zeolite powder impregnated or otherwise incorporated therein.

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Номер записи: 41

21-02-2013 дата публикации

Immunostimulatory compositions and methods of use thereof

Номер: US20130045224A1

Автор: Ian Sims, Jonathan Mcdonald Counsell Stephens, Ralf Christian Schlothauer, Swapna Gannabathula

Принадлежит: Comvita New Zealand Ltd

Immunostimulatory compositions and methods of use are described to either enhance or diminish the immune stimulation effects of a honey or honey isolate by recognition of the presence of type II arabinogalactan compounds and utilising this knowledge to tailor the concentration of such compounds thereby adjusting the immune stimulation effects.

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Номер записи: 42

14-03-2013 дата публикации

Infection activated wound caring compositions and devices

Номер: US20130064772A1

Автор: Gerald F. SWISS, Robert M. Moriarty, Stefan Schwabe

Принадлежит: Indicator Systems International Inc

Provided are wound caring compositions and devices containing a pH-sensitive, preferably acid degradable, components contained in a water-permeable and hydronium ion permeable material. The pH-sensitive component encloses an antibiotic which is released to the wound upon infection by a microorganism at the wound site, and/or encloses a pH indicator. The antibiotic release is triggered by the microorganism's production of CO 2 at the wound site which forms carbonic acid, lowers the pH at the pH sensitive components, and thus results in rupture of the liposome.

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Номер записи: 43

21-03-2013 дата публикации

MEDICAL TREATMENT APPLICATIONS OF SWELLABLE AND DEFORMABLE MICROSPHERES

Номер: US20130071322A1

Автор: Figuly Garret D.

Принадлежит: E I DU PONT DE NEMOURS AND COMPANY

A method for medical treatment was developed in which microspheres with novel properties are administered in a mammal. The microspheres are made using a novel process that results in microspheres with new combined properties of high density, low fracture, high swell capacity, rapid swell, and deformability following swell. These microspheres may be administered for void filling, tissue bulking, non-vasculature occlusion, body fluid absorption, and delivery of medications. 1. A wound covering comprising a support material and microspheres , said microspheres being prepared by a process comprising: (i) water;', (A) if said monomer is acrylamide, methacrylamide, N-substituted acrylamides, 2-hydroxyethyl acrylate, or 2-hydroxyethyl methacrylate, said monomer is used in combination with at least one other monomer selected from subgroup 1 consisting of: acrylic acid, methacrylic acid, salts of acrylic acid and methacylic acid, 2-acryloylethane-sulfonic acid, 2-methacryloylethane-sulfonic acid, salts of 2-acryloylethane-sulfonic acid and 2-methacryloylethane-sulfonic acid, styrene-sulfonic acid, and salts of styrene-sulfonic acid;', '(B) if said first solution contains at least one monomer from subgroup 2 consisting of acrylic acid, methacrylic acid, salts of acrylic acid and methacylic acid, acrylamide, methacrylamide, N-substituted acrylamides, N-substituted methacrylamides, 2-hydroxyethyl acrylate, and 2-hydroxyethyl methacrylate, but does not contain a monomer selected from subgroup 3 consisting of 2-acryloylethane-sulfonic acid, 2-methacryloylethane-sulfonic acid, salts of 2-acryloylethane-sulfonic acid and 2-methacryloylethane-sulfonic acid, styrene-sulfonic acid, and salts of styrene-sulfonic acid, then the pH of the first solution is at least about 3;', '(C) if said first solution contains at least one monomer from subgroup 3 consisting of 2-acryloylethane-sulfonic acid, 2-methacryloylethane-sulfonic acid, salts of 2-acryloylethane-sulfonic acid and 2- ...

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Номер записи: 44

21-03-2013 дата публикации

Tissue treatment systems and methods having a non-tactile-stimulus-activated, macroscopically-deforming material

Номер: US20130072850A1

Автор: Christopher Brian Locke, Timothy Mark Robinson

Принадлежит: Individual

A system for treating a tissue site of a patient includes a dressing filler adapted to be positioned at the tissue site. The dressing filler includes a base and a plurality of nodes extending from the base. The base further includes a plurality of openings disposed in the base. At least one of the plurality of nodes is comprised of a non-tactile-stimulus-activated, macroscopically-deforming (NTSAMD) material.

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Номер записи: 45

28-03-2013 дата публикации

Hemostatic sponge

Номер: US20130079695A1

Автор: Daniel J. Burns, Denny Lo, Francis X. Hursey, Giacomo Basadonna, Raymond J. Huey

Принадлежит: Z Medica LLC

A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

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Номер записи: 46

04-04-2013 дата публикации

System and method for treating leg ulcers

Номер: US20130085435A1

Автор: Khaled El-Tahlawy, Thomas S. Murphy

Принадлежит: Andover Healthcare Inc

In one aspect, a wound treatment system includes an inner layer comprising a foam material impregnated with a zinc oxide containing composition with or without calamine and/or ichthammol and in the presence or absence of antimicrobial agent (inorganic and/or organic). An optional outer layer comprises a short/long stretch compression bandage. In another aspect, a method of manufacturing the foam article impregnated with the zinc oxide containing composition is disclosed. In yet another aspect, a method of applying the wound treatment system to a patient's leg is disclosed. In still another aspect, a kit is provided including a foam layer impregnated with a zinc oxide containing composition; optionally, an elastic bandage component (e.g., long or short stretch elastic bandage); and, optionally, an outer stocking or sleeve, wherein the bandage system components are packaged together.

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Номер записи: 47

18-04-2013 дата публикации

Method of forming hemostatic products

Номер: US20130096479A1

Автор: Curtis E. Olson, Philip A. Messina

Принадлежит: St Teresa Medical Inc

A hemostatic product having a plurality of hemostatic layers. Each of the hemostatic layers includes a dextran support and at least one hemostatic agent, which is selected from the group consisting of thrombin and fibrinogen. The hemostatic layers are arranged in a stacked configuration.

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Номер записи: 48

25-04-2013 дата публикации

Control of Female Body Odours

Номер: US20130102981A1

Автор: Behan John Martin, Cawkill Paula Maria, Evans Michael Gordon, Perring Keith Douglas

Принадлежит: Quest International Services B.V.

The invention concerns the control of female body odours, particularly odours associated with body fluids, namely products of the genito-urinary tract, such as menstrual or catamenial fluids, vaginal fluids, urine, by use of low odour compositions of fragrance materials. The composition of fragrance material includes at least 5% of one or more musks and at least 5% of one or more salicylates. 1. A method of counteracting or reducing odours associated in use with an article selected from sanitary towels or napkins and panty liners , comprising providing in or on the article a composition of fragrance materials having an odour intensity index of less than about 110 , the composition comprising:at least 5% w/w of at least one musk selected from the group consisting of cyclohexadecanolide (dihydroambrettolide); cyclopentadecanone (Exaltone) cyclo-1,13-ethylenedioxy-tridecan-1,13-dione (ethylene brassylate); 11-oxahexadecanolide (Musk R1); ethylene 1,12-dodecanedioate (Musk MC4/Musk C14); 1,oxa-5(6)-cyclohexadecen-16-one (habanolide) and cyclopentadecanolide (Exaltolide); andat least 5% w/w of at least one single salicylate.23-. (canceled)4. An article selected from a sanitary towel or napkin and a panty liner , wherein the article includes a composition of fragrance materials having an odour intensity index of less than about 110 , the composition comprising:at least 5% w/w of at least one musk selected from the group consisting of cyclohexadecanolide (dihydroambrettolide); cyclopentadecanone (Exaltone) cyclo-1,13-ethylenedioxy-tridecan-1,13-dione (ethylene brassylate); 11-oxahexadecanolide (Musk R1); ethylene 1,12-dodecanedioate (Musk MC4/Musk C14); 1,oxa-5(6)-cyclohexadecen-16-one (habanolide) and cyclopentadecanolide (Exaltolide); andat least 5% w/w of at least one salicylate.5. An article according to claim 4 , comprising a liquid-absorbent pad for absorbing female bodily fluids comprising products of the genito-urinary tract.6. An article according to claim 5 , ...

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Номер записи: 49

02-05-2013 дата публикации

Compositions and methods for treating full thickness burn injuries

Номер: US20130108670A1

Автор: Jeffrey S. Guy, Samuel Eugene Lynch

Принадлежит: Biomimetic Therapeutics LLC

The present invention provides compositions and methods for treating full thickness burn injuries. The present invention provides compositions and methods for promoting healing and regeneration of impaired or damaged tissue at a site of such a full thickness burn injury, as well as promoting vascularization and angiogenesis in regenerating tissue at such sites.

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Номер записи: 50

09-05-2013 дата публикации

Absorbent article with dual core

Номер: US20130116646A1

Автор: Miguel Alvaro Robles

Принадлежит: Procter and Gamble Co

An absorbent article. The absorbent article includes a topsheet having a body contacting surface, a backsheet joined to said topsheet, and an absorbent core disposed between the topsheet and the backsheet, wherein the absorbent core has an upper layer and a lower layer.

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Номер записи: 51

23-05-2013 дата публикации

Superabsorbent Comprising Pyrogenic Aluminum Oxide

Номер: US20130130895A1

Автор: Norbert Herfert, Thomas Daniel

Принадлежит: BASF SE

Superabsorbents comprising pyrogenic aluminum oxide exhibit a low caking tendency coupled with good absorption properties and rapid water absorption.

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Номер записи: 52

13-06-2013 дата публикации

Hemostasis Composition with Magnetite

Номер: US20130150652A1

Автор: John Hen, Mark Travi, Talmadge Kelly Keene

Принадлежит: Biolife LLC

A composition and method of arresting the flow of blood from a bleeding wound. The composition preferably includes an anhydrous salt ferrate compound preferably combined with an effective amount of an insoluble cation exchange material and an effective amount of anhydrous Magnetite mixed uniformly together. Povidone iodine may be added for enhanced antimicrobial properties. In the method, a quantity of the composition is magnetically attached to a surface of a magnet, after which the powderous mixture is applied to the wound by pressing the surface covered with the powderous compound against the wound for a time sufficient to clot the blood to arrest substantial further blood flow from the wound.

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Номер записи: 53

20-06-2013 дата публикации

ANTIBACTERIAL WOUND DRESSING

Номер: US20130152309A1

Автор: BRAY Roger

Принадлежит: ConvaTec Technologies Inc.

An antibacterial wound dressing is based on or derived from gel-forming fibres such as carboxymethyl cellulose or alginate fibres having silver ions linked thereto at some but not all of the exchangeable sites such that the distribution of silver ions over the exchangeable sites is substantially uniform. The silvered fibres for the wound dressing can be prepared by contacting an assembly of precursor gel-forming fibres having exchangeable sites under conditions which do not cause irreversible gelling of the fibres with an amount of a solution containing silver ions so as to link silver ions at some but not all of the exchangeable sites, the whole of the assembly of precursor gel-forming fibres being contacted essentially simultaneously with the entire solution containing silver ions. 1. An antibacterial wound dressing derived from gel-forming fibres having silver ions linked to not more than about 20% of the exchangeable sites on the gel-forming fibres , wherein the distribution of silver ions over the exchangeable sites is essentially uniform as shown by the uniform coloration of the dressing.2. An antibacterial wound dressing according to claim 1 , wherein the silver ions are linked to not more than 10% of the exchangeable sites on the gel-forming fibres.3. An antibacterial wound dressing according to claim 1 , wherein the gel forming fibres comprises lyocell-derived fibres.4. An antibacterial wound dressing according to claim 1 , wherein the gel-forming fibres comprises carboxymethylated cellulose fibres.5. An antibacterial wound dressing according to claim 1 , wherein the gel-forming fibres comprises calcium alginate or sodium/calcium alginate fibres6. An antibacterial wound dressing according to claim 1 , wherein the silver content of the silvered fibres is from 0.01 to 10% by weight.7. An antibacterial wound dressing according to claim 1 , wherein the silver content of the silvered fibres is from 0.1 to 5% by weight.8. An antibacterial wound dressing according ...

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Номер записи: 54

20-06-2013 дата публикации

METHODS FOR STEPWISE DEPOSITION OF SILK FIBROIN COATINGS

Номер: US20130156844A1

Автор: Kaplan David L., WANG Xianyan

Принадлежит: TRUSTEES OF TUFTS COLLEGE

The invention provides a method for the controlled assembly of layered silk fibroin coatings using aqueous silk fibroin material. The methods described herein can be used to coat substrates of any material, shape, or size. Importantly, the described methods enable control of the biomaterial surface chemistry, thickness, morphology and structure using layered thin film coatings, or bulk coatings. Furthermore, the methods can be performed in all water and do not require intensive chemical processing enabling controlled entrapment of labile molecules such as, drugs, cytokines, and even cells or viruses to generate functional coatings that can be used in a variety of applications. 1. A composition comprising a substrate coated with silk fibroin , wherein the silk fibroin coating the substrate comprises a therapeutic agent.2. The composition of claim 1 , wherein the composition is selected from the group consisting of vascular wound repair devices claim 1 , hemostatic dressings claim 1 , patches claim 1 , glues claim 1 , and sutures.3. The composition of claim 1 , wherein the therapeutic agent comprises an agent for enhancing wound healing.4. The composition of claim 1 , wherein the therapeutic agent is selected from the group consisting of antiproliferatives claim 1 , antineoplastics claim 1 , antiinflammatories claim 1 , antiplatelets claim 1 , anticoagulants claim 1 , antifibrins claim 1 , antithrombins claim 1 , antimitotics claim 1 , antibiotics claim 1 , antioxidans claim 1 , and combinations thereof.5. The composition of claim 1 , wherein the composition is formulated for topical administration.6. The composition of claim 1 , wherein the therapeutic agent is present as a liquid or a finely divided solid.7. The composition of claim 1 , wherein the therapeutic is controlled released over a period of about 2 to about 90 days.8. The composition of claim 1 , wherein the therapeutic agent is released in an amount of about 1 ng/day to 1 mg/day.9. The composition of claim ...

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Номер записи: 55

20-06-2013 дата публикации

Use of a safe, green and biodegradable absorptive material in the construction of diapers, feminine hygiene and adult incontinence products and devices

Номер: US20130158134A1

Автор: Martin Samuel Kofele

Принадлежит:

A method of making absorbent core systems for the construction of absorbent articles such as baby care, feminine hygiene or adult incontinence products. The method essentially replaces the traditional synthetic acrylic acid polymer-based hydrophilic material mixed with wood pulp fiber in the absorbent core with a safer, green, biodegradable plant-based material. 1Salvia hispanica. The use of seeds or derivatives therefrom of and related species of the mint plant family Lamiaceae (chia seeds) partially or exclusively as the absorbent core in the construction of baby care , feminine hygiene and adult incontinence products and devices for the hygienic collection and disposal of body and other fluids or spillage.2. The addition of chia seeds or derivatives therefrom to solids , liquids , woven and non-woven fabric , tissue and the like to enhance their absorbent capacity for water and fluids to include body fluids such as urine , feces , menses , discharges , sweat , saliva , tears , pus , exudates and other fluids or spillage.3. The use of chia seeds or derivatives therefrom in delivery systems to improve compliance or the bioavailability of drugs , vaccines , antigens etc or to target cells in vitro or in vivo This patent application cross references U.S. Provisional Patent No. 61/575,708 of the same title, filed on 25 Aug. 2011 by Esingila Health and Wellness Consultants, Inc., 2916 Cabin Creek Drive, Burtonsville, Md. 20866.None of the research for this work was done under federal government sponsorship.The body discharges end products of its catabolism, digestion and other processes to the exterior. These substances frequently exit the body as liquids and semi-solids such as urine, feces, menses, sweat or gas. Despite the fact that the elimination of these products is essential to the house-keeping functions of the body, it simultaneously poses major hygiene challenges for appropriate socialization and acceptable decorum. Various methods have been developed to meet ...

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Номер записи: 56

27-06-2013 дата публикации

Multilayer polymeric drug delivery system

Номер: US20130164347A1

Автор: Abla Abu-Zayyad Creasey, II Michael J. Trezza, Michel Gensini

Принадлежит: Individual

The invention relates to a customizable, solvent-free sustained release medical device for wound closure, wound healing, and the sustained release of an active. The device of the invention is composed of at least a polymeric carrier layer and optionally an oxidized regenerated cellulose layer(s). Polymeric barrier layers can be added to modify the release profile (burst, time of release, etc.) of the selected bioactive agent(s).

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Номер записи: 57

27-06-2013 дата публикации

Location of Fatty Acid Esters on Tampons and Toxin Inhibiting Efficacy

Номер: US20130165879A1

Автор: Ching-Yun M. Yang, Linda M. Pierson, Susan K. Brown-Skrobot, JR.

Принадлежит: McNeil PPC Inc

The application of active ingredients, exemplified by GML, to absorbent fibers, such as rayon fibers, used in tampon manufacture at very low levels has been found to maintain efficacy in the inhibition of the production of toxic shock syndrome toxin one (TSST-1) produced by S. aureus without overtly killing the microorganism to achieve the desired reduction while avoiding undesired test results that suggest the presence of “impurities” in some jurisdictions.

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Номер записи: 58

27-06-2013 дата публикации

Antimicrobial disposable absorbent articles

Номер: US20130165880A1

Автор: Alexis S. Statham, Bathsheba E. Chong Conklin, David T. Amos, Leigh E. Wood, Michael J. Svarovsky

Принадлежит: 3M Innovative Properties Co

Disposable absorbent articles comprising an absorbent material and an antimicrobial composition are disclosed. The antimicrobial composition includes a carrier comprising fatty alcohol and a poly(alkyleneoxy) polymer, and an antimicrobial agent. The antimicrobial composition may be coated on to component substrates such as nonwovens and films, that are incorporated into disposable absorbent articles, such as disposable infant diapers, adult incontinence articles, feminine hygiene articles such as sanitary napkins, wound dressings, bandages, panty liners and tampons, personal care wipes and household wipes to provide odor control, and control of microbial growth.

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Номер записи: 59

04-07-2013 дата публикации

Process for Preparing Curcumin Encapsulated Chitosan Alginate Sponge Useful for Wound Healing

Номер: US20130171215A1

Автор: Chandana Mohanty, Sahoo Sanjeeb Kumar

Принадлежит: INSTITUTE OF LIFE SCIENCES

A process for preparing curcumin encapsulated chitosan alginate sponge comprising the steps of: incorporating curcumin in a fluid phase of oleic acid; subjecting the mixture to a step of emulsification with chitosan solution by homogenization; emulsifying the resultant solution with alginate solution by homogenization; lyophilizing the final emulsion by freeze drying to produce curcumin loaded AC sponge. 1. A process for preparing curcumin encapsulated chitosan alginate sponge comprising the steps of:a) incorporating curcumin in a fluid phase of oleic acid to form a curcumin-oleic acid mixture;b) subjecting the curcumin-oleic acid mixture to a step of emulsification with chitosan solution by homogenization;c) emulsifying the solution formed in step b) with alginate solution by homogenization; andd) lyophilizing the emulsion of step c) by freeze drying to produce curcumin loaded AC sponge.2. The process as claimed in claim 1 , wherein the said alginate solution is prepared by dissolving sodium alginate powder in deionized water at room temperature.3. The process as claimed in claim 1 , wherein the said chitosan solution is prepared by dissolving chitosan powder in 20 ml of deionized water containing acetic acid at room temperature.4. The process as claimed in claim 1 , wherein the curcumin-oleic acid mixture is emulsified with chitosan for 2 minute.5. The process as claimed in claim 1 , wherein the solution formed in step b) is homogenized with alginate solution for 3 minutes.6. The process as claimed in claim 1 , wherein the step of lyophilization is performed for 3 days at 80° C. and less than 10 μιτι mercury pressure.7. The process as claimed in claim 1 , wherein the alginate to chitosan ratio is selected from a group consisting of 1:1 claim 1 , 1:2 and 1:3.8. The process as claimed in claim 1 , wherein the ratio of alginate to chitosan is 1:2.9. A sponge composition as claimed in claim 1 , wherein a hydrophobic agent curcumin bind to a hydrophobic core of oleic ...

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Номер записи: 60

04-07-2013 дата публикации

Anti-microbial metal organic framework

Номер: US20130171228A1

Автор: Russell Edward Morris

Принадлежит: University of St Andrews

The present invention relates to metal organic framework materials which possess anti-microbial properties. The present invention also provides methods of preparing such metal organic framework materials and uses of the metal organic framework materials to prevent or treat microbial infections, or provide surfaces which limit contamination by micro-organisms.

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Номер записи: 61

25-07-2013 дата публикации

Wound care system and bacteridical methods and devices

Номер: US20130189345A1

Автор: Diefeng Gu, Helmut Baumgart

Принадлежит: Old Dominion University Research Foundation

A variety of article and systems including wound care systems, methods for making the wound care systems, bactericidal, and methods for treating wounds using these systems are disclosed. The wound care systems may include a first material comprising one or more fibers or porous media. The one or more fibers or porous media may be coated with a second material that is capable of inhibiting the growth of bacteria and killing the bacteria to render the wound care system sterile, increasing the absorbency of the first material, or both upon exposure to light. The first material may be cotton, or any suitable fibrous material, the second material may be TiO 2 , and the light may be UV or visible light. A variety of methods including ALD may be used to coat the first material.

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Номер записи: 62

01-08-2013 дата публикации

Biofilm resistant materials

Номер: US20130195841A1

Автор: Jeffrey S. Gabbay

Принадлежит: CUPRON SCIENTIFIC Ltd

This invention provides a biofilm resistant material comprising an active agent, which active agent consists essentially of an insoluble copper oxide at a concentration of between 3 and 10% w/w of said biofilm resistant material and uses thereof.

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Номер записи: 63

22-08-2013 дата публикации

SILVER CONTAINING WOUND DRESSING

Номер: US20130217649A1

Автор: WOODS David Malcolm

Принадлежит: ConvaTec Technologies Inc.

A wound dressing having anti-microbial activity comprises a first fibre capable of bonding with silver (1) cations. The wound dressing comprises a blend of the first fibre to which silver (1) cations are bonded and a second fibre which is substantially free from silver. The wound dressing comprises from 0.01 to 5.0 percent by weight of silver (1) cations, based on the weight of fibre. 1. A wound dressing having anti-microbial activity , comprising a first fibre which is substantially insoluble in water having silver (I) cations bonded thereto and discoloring on exposure to light , wherein the wound dressing consists of a uniform blend of the first fibre and a second fibre of lyocell which is substantially free from silver , said wound dressing comprising from 0.01 to 5.0 percent by weight of silver (I) cations based on the total weight of first and second fibres , whereby the discoloration of the blend on exposure to light is lessened compared with the discoloration on exposure to light of a batch of the first fibre having the same average amount of silver cations present as is present in the blend.2. A wound dressing according to claim 1 , which comprises from 0.01 to 4.0 percent by weight of silver (I) cations based on the total weight of first and second fibres.3. A wound dressing according to claim 3 , which comprises from 0.25 to 3.0 percent by weight of silver (I) cations based on the total weight of first and second fibres.4. A wound dressing according to claim 1 , wherein the first fibre is selected from a group consisting of a carboxymethylcellulose fibre claim 1 , an alginate fibre claim 1 , a chitosan fibre claim 1 , a chitosan derivative fibre and an acrylic fibre.5. A wound dressing according to claim 4 , wherein the first fibre is a carboxymethylcellulose fibre and the wound dressing contains from 1.0 to 2.0 percent by weight of silver (I) cations claim 4 , based on the weight of the fibre.6. A wound dressing according to claim 4 , wherein the first ...

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Номер записи: 64

29-08-2013 дата публикации

ACTIVATED LEUKOCYTE CONDITIONED SUPERNATANT AND USES FOR WOUND HEALING

Номер: US20130224148A1

Автор: BAIN Eilat, BUBIS Marina, Ginis Irene, SHIRVAN Mitchell

Принадлежит:

Disclosed are therapeutic, activated leukocyte conditioned supernatants, methods of making them, and methods of using the conditioned supernatants to repair or promote healing of wounds. 162-. (canceled)63. A substantially cell-free activated leukocyte-conditioned supernatant (ALCS) , wherein the ALCS is made by(a) obtaining activated leukocytes; contacting the activated leukocytes with an incubation medium to form an incubation composition; incubating the incubation composition at a temperature and time sufficient to increase the concentration of at least one cytokine or growth factor in the incubation composition; and removing leukocytes from the incubation composition to produce a substantially cell-free ALCS activated leukocyte-conditioned supernatant (ALCS), or(b) incubating human leukocytes under conditions of time and temperature to activate the leukocytes; subjecting the leukocytes to hypo-osmotic shock; adding to the leukocytes subjected to the hypo-osmotic shock to a salt solution in an amount which restores isotonicity; separating the leukocytes from the resulting isotonic solution; mixing the separated leukocytes with serum to form an incubation composition; incubating the incubation composition under conditions of time and temperature to increase the concentration of at least one cytokine or growth factor in the incubation composition; and separating the leukocytes and other cellular matter from the incubation composition to produce a substantially cell-free ALCS.64. A substantially cell-free activated leukocyte-conditioned supernatant (ALCS) comprising at least about 1000 pg/mL human IL-8 , at least about 10-20 pg/mL human IL-6 , and at least about 20 pg/mL human TNFalpha.65. The use of the ALCS according to any one of or in the manufacture of a medicament for the treatment of a wound or the inhibition of the onset of infection in a wound; (i) the wound is a decubital ulcer, a pressure ulcer, a lower extremity ulcer, tendonitis, a deep sternal wound, a ...

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Номер записи: 65

12-09-2013 дата публикации

ODOR-CONTROLLING BODILY FLUID ABSORBER

Номер: US20130236414A1

Автор: Schneider Charles A., Schneider David J.

Принадлежит:

An odor-controlling bodily fluid absorbent member comprises (a) an absorbent material or substrate; and (b) a halo active aromatic sulfonamide compound of Formula (I): 2. The absorbent member of claim 1 , wherein the absorbent material is a polymer claim 1 , cellulosic fiber claim 1 , or a wood fluff.3. The absorbent member of claim 1 , wherein Ris methyl claim 1 , COOH claim 1 , COOM claim 1 , chlorine claim 1 , fluorine claim 1 , NO claim 1 , or methoxy.4. The absorbent member of claim 1 , wherein Ris selected from COOH claim 1 , COOM claim 1 , COOR′ claim 1 , CON(R″) claim 1 , CN claim 1 , NO claim 1 , halogen claim 1 , and substituted or unsubstituted Calkyl.5. The absorbent member of claim 1 , wherein Rand Rare identical to each other; and R claim 1 , R claim 1 , and Rare hydrogen.6. The absorbent member of claim 1 , wherein Rand Rare hydrogen; and R claim 1 , R claim 1 , and Rare identical to each other.7. The absorbent member of claim 1 , wherein Ris selected from COOH claim 1 , COOM claim 1 , COOR′ claim 1 , and CON(R).8. The absorbent member of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , and Rare independently selected from hydrogen claim 1 , COOH claim 1 , COOM claim 1 , COOR′ claim 1 , CON(R″) claim 1 , NO claim 1 , halogen claim 1 , and substituted or unsubstituted C-Calkyl.9. The absorbent member of claim 1 , wherein Ris COOH or COOM; and R claim 1 , R claim 1 , R claim 1 , and Rare independently selected from hydrogen claim 1 , NO claim 1 , halogen claim 1 , and substituted or unsubstituted C-Calkyl.10. The absorbent member of claim 1 , wherein the absorbent member further comprises a second different sulfonamide compound.11. The absorbent member of claim 10 , wherein the weight ratio of the two sulfonamide compounds is from about 90:10 to about 10:90.12. The absorbent member of claim 10 , wherein the two compounds are N-chloro-p-toluenesulfonamide and N-chloro-p-carboxysulfonamide.13. The absorbent member of claim 10 , wherein ...

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Номер записи: 66

19-09-2013 дата публикации

Wound and therapy compress and dressing

Номер: US20130245578A1

Автор: Aaron N. Ingram, Mark H. Bruder

Принадлежит: Bruder Healthcare Co

A method of providing moisture therapy to a subject by applying a moist therapy compress against a treated body portion. The moist therapy compress includes a fluid-permeable shell, a flexible backing fastened to the shell to define an enclosure, and a hydrophilic zeolite fill granules loosely contained within the enclosure. The therapy compress is exposed to a source of moisture to cause absorption of water into the a hydrophilic zeolite, and the moisture is delivered from the hydrophilic zeolite through the fluid permeable shell to the treated body portion.

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Номер записи: 67

03-10-2013 дата публикации

Particulate substances comprising ceramic particles for delivery of biomolecules

Номер: US20130259942A1

Автор: Christophe Jean Alexandre BARBÉ, Kim Suzanne Finnie, Samuel Knight, Toby Johnston Passioura

Принадлежит: Australian Nuclear Science and Technology Organization

A particulate substance comprising particles of a ceramic matrix bearing a functional group, the functional group being capable of promoting penetration of the particles into cells, and a biomolecule disposed within pores of the particles, the biomolecule being releasable from the particles by dissolution of the ceramic matrix.

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Номер записи: 68

17-10-2013 дата публикации

Method for modifying non-woven chitosan fabric

Номер: US20130273235A1

Автор: Hongjun YI, Weidong Yang, Yuhua Huang

Принадлежит: QINGDAO JIFA NEW MATERIAL CO Ltd

A method for modifying a non-woven fabric of chitosan fiber. The method includes: adding succinic anhydride to an industrial alcohol, ethanol, or acetone; controlling the mass ratio of succinic anhydride to the non-woven fabric at between 0.8 and 3.5; and stirring the resulting mixture until the succinic anhydride has dissolved to yield a succinic anhydride mixed solution; placing the succinic anhydride mixed solution in a constant temperature shaking bath; heating the succinic anhydride mixed solution; adding an HCl solution to the succinic anhydride mixed solution, and stirring evenly to yield a HCl mixed solution; immersing the non-woven fabric in the HCl mixed solution; dehydrating; immersing the non-woven fabric in ethanol or acetone; immersing the non-woven fabric in anhydrous ethanol or pure acetone; dehydrating; and air drying the non-woven fabric.

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Номер записи: 69

24-10-2013 дата публикации

METHOD OF INDUCING HEMOSTASIS IN A WOUND

Номер: US20130280321A1

Автор: Messina Philip A., Olson Curtis E.

Принадлежит:

A method of inducing hemostasis in a wound using a hemostatic product. A dextran support is provided. At least one hemostatic agent stabilizer is mixed with at least one hemostatic agent to form a hemostatic agent and stabilizer mixture. The at least one hemostatic agent includes at least one of thrombin and fibrinogen. The hemostatic agent and stabilizer mixture is associated with the dextran support. The hemostatic product is applied to the wound in which a bodily fluid is present. The at least one hemostatic agent is released from the hemostatic product to induce hemostasis in the wound. 1. A method of inducing hemostasis in a wound , comprising the step of fabricating a hemostatic product that comprises:providing a dextran support;mixing at least one hemostatic agent stabilizer with at least one hemostatic agent to form a hemostatic agent and stabilizer mixture, wherein the at least one hemostatic agent comprises at least one of thrombin and fibrinogen; andassociating the hemostatic agent and stabilizer mixture with the dextran support;applying the hemostatic product to the wound in which a bodily fluid is present;releasing the at least one hemostatic agent from the hemostatic product; andinducing hemostasis in the wound.2. The method of claim 1 , wherein the at least one hemostatic agent stabilizer comprises sucrose that is provided in the hemostatic product at a concentration of up to about 5 percent by weight.3. The method of claim 1 , wherein fabricating the hemostatic product further comprises mixing a solubility enhancing agent with the at least one hemostatic agent stabilizer prior to mixing the at least one hemostatic agent stabilizer with the at least one hemostatic agent.4. The method of claim 3 , wherein the solubility enhancing agent is dextran and wherein the solubility enhancing agent is provided at a concentration of up to about 1 percent by weight of the hemostatic product.5. The method of claim 1 , wherein the hemostatic product does not exhibit ...

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Номер записи: 70

31-10-2013 дата публикации

High strength chitin composite material and method of making

Номер: US20130287836A1

Автор: Donald E. Ingber, Javier Gomez Fernandez

Принадлежит: Harvard College

The present invention is directed to a composite laminar material with high mechanical strength and methods of fabricating the material. The invention also provides a method of attaching a medical implant device to tissue.

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Номер записи: 71

31-10-2013 дата публикации

Gas based wound and tissue therapeutics

Номер: US20130289471A1

Автор: Bruce Spiess, Chris Stern, Gary Bowlin, Gary S Huvard, Gurbhagat S Sandhu, Kevin R. Ward, Robert Diegelmann

Принадлежит: Oxygen Biotherapeutics Inc, Virginia Commonwealth University

This invention provides articles of manufacture and bandages comprising compartments and layers comprising oxygen and other therapeutic gas storage forms and perfluorocarbons. This invention also provides for methods of delivering oxygen and other therapeutic gases to a tissue in a subject comprising a administering to the tissue a composition comprising a perfluorocarbon and a oxygen or therapeutic gas storage form, so as to thereby deliver oxygen or the therapeutic gas to the tissue.

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Номер записи: 72

21-11-2013 дата публикации

PHARMACEUTICAL COMPOSITION AND DEVICE FOR PREVENTING, TREATING AND CURING ULCERS ON A DIABETIC FOOT AND OTHER WOUNDS, WHICH INCLUDES SNAIL SLIME FROM THE SPECIES CRYPTOPHALUS ASPERSUS OR HELIX ASPERSA MULLER AND PHARMACEUTICALLY ACCEPTABLE CARRIERS AND/OR ADDITIVES

Номер: US20130309296A1

Автор: Galdames Flores Nieves, Moreno González Elmo Ernesto

Принадлежит:

The present invention is related to a pharmaceutical composition comprising snail slime of () (5% to 50%) and marigold extract, propolis and/or almond oil and pharmacologically accepted additives for the prevention additives and/or pharmaceutically acceptable excipients to form a formulation of intermediate to high viscosity (200 to 1000 Pa-s). This invention also relates to the use of a composition which can be formed as a cream or a gel, is preferably soaked in gauze, and shaped as a bandage or sock for the treatment and cure of diabetic foot ulcers and other severe wounds, particularly those associated with diabetes, gout, Lesch Nyhan syndrome or other conditions to the skin, including, keratosis, onychomycosis, ringworm, among others. 1Helix aspersa MüllerCryptophalus aspersus. A pharmaceutical composition for use in serious injury that consists of about 15% to 30% of snail () dissolved in a body cream base containing additives and/or pharmaceutically acceptable excipients together with natural products such as marigold extract , propolis and/or almond oil , generating a viscosity formulation of 200 to 1000 Pa-s.2Helix aspersa MüllerCryptophalus aspersus. A pharmaceutical composition according to that consists of snail slime () claim 1 , marigold extract claim 1 , propolis and/or almond oil and additives and/or pharmaceutically acceptable excipients that generate a viscosity formulation between 50-100 Pa-s.3. A pharmaceutical composition according to claim 1 , that is soaked in gauze type bandage shaped fabric to be applied to advanced ulcerous wounds or other serious skin conditions similar or sock to be applied to advanced diabetic foot ulcers.4. The composition of that is in a state of cream or gel of medium to high viscosity.5Helix aspersa Muller. Procedure for obtaining a composition according to which comprises a) formulation on the basis of sterilized body cream and chilled with low content of snail slime formulation claim 1 , b) addition of snail slime ...

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Номер записи: 73

21-11-2013 дата публикации

COMPOSITION I - I AND PRODUCTS AND USES THEREOF

Номер: US20130310780A1

Автор: Phillips Marcus Damian

Принадлежит: Smith & Nephew PLC

A curable composition apportioned between at least one Part A and at least one Part B, the Parts sealed within barrier means in manner to prevent contamination thereof, the composition comprising: (i) one or more alkenyl-containing prepolymers having at least one alkenyl moiety per molecule, ii) one or more SiH-containing prepolymers having at least one SiH unit per molecule, and additionally: (iii) a catalyst for curing by addition of alkenyl-containing prepolymer (i) to SiH-containing prepolymer (ii), wherein the at least one Part A and at least one Part B are provided within or upon at least two respective receptacles or supports and are adapted to be dispensed or released therefrom in cooperative manner facilitating intimate contact and curing thereof, wherein the receptacle(s) or support(s) for at least one of Part A and Part B is thermally stable at elevated temperature of 123 C for a period in excess of 18 hours, methods for preparing the composition, methods for sterilisation thereof, medical and non-medical use thereof, a device incorporating the composition, and a precursor therefor including its sterilisable precursor composition, in particular a terminally sterilisable or terminally sterile composition for medical use, particularly in wound therapy, more particularly as a wound packing material which can be shaped and configured to the shape of a wound, most particularly for application in negative pressure wound therapy (NPWT). 1. A curable composition , apportioned between at least one Part A and at least one Part B , the composition comprising:one or more alkenyl-containing polymers having at least one, or at least two, alkenyl moiety per molecule,one or more SiH-containing polymers having at least one, or at least two, SiH unit per molecule,a catalyst for curing by addition of an alkenyl-containing polymer to a SiH-containing polymer (ii), anda blowing agent configured to evolve gas as part of or during the curing reaction,wherein the at least one ...

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Номер записи: 74

28-11-2013 дата публикации

Absorbent Article Comprising A Synthetic Polymer Derived From A Renewable Resource And Methods Of Producing Said Article

Номер: US20130313149A1

Автор: Bryn Hird, Eric Ted Addington

Принадлежит: Procter and Gamble Co

An absorbent article is disclosed having a topsheet, a backsheet joined with the topsheet, an absorbent core disposed between the topsheet and the backsheet, and a synthetic superabsorbent polymer derived from a first renewable resource via at least one intermediate compound, wherein said superabsorbent polymer exhibits a defined Saline Flow Conductivity value and Absorption Against Pressure value. Alternately, an absorbent article is disclosed having a synthetic polyolefin derived from a first renewable resource via at least one intermediate compound. The synthetic polyolefin exhibits defined performance characteristics making the polyolefin particularly useful in certain components of the absorbent article. Methods for making the aforementioned absorbent articles are also disclosed.

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Номер записи: 75

28-11-2013 дата публикации

WOUND DRESSINGS COMPRISING CHLORITE

Номер: US20130316020A1

Автор: Buyuktimkin Nadir, Buyuktimkin Servet, King-Smith Dominic, Kisak Edward T., Newsam John M., Singh Jagat

Принадлежит:

This application described a wound dressing comprising an absorbent material, an effective amount of chlorite and an amount of a base to provide a pH of the dressing material greater than or equal to about (). Advantageously, the wound dressings of the present application provide a convenient source of chlorite that is stable and easy to use. 169-. (canceled)70. A wound dressing comprising an absorbent material , an effective amount of chlorite and an amount of a base to provide a pH of the absorbent material greater than or equal to about 10.71. The wound dressing of claim 70 , wherein the chlorite added to the absorbent material is a stabilized chlorite composition.72. The wound dressing of claim 71 , wherein the stabilized chlorite composition is OXO-K993 claim 71 , or a composition comprising about 0.01-0.1% claim 71 , 0.1-1% claim 71 , 1-10% claim 71 , 10-20% claim 71 , 20-30% claim 71 , 30-50% or 50-90% (w/v) of OXO-K993.73. The wound dressing of claim 71 , wherein the stabilized chlorite composition is a composition comprising Oxovasin™ or a composition comprising about 2% (w/v) OXO-K993.74. The wound dressing of claim 71 , wherein the stabilized chlorite composition is a composition comprising about 2% (w/v) OXO-K993 claim 71 , about 2% (w/v) glycerol and about 96% (w/v) water.75. The wound dressing of claim 70 , wherein the chlorite is a chlorite salt selected from sodium chlorite claim 70 , potassium chlorite claim 70 , magnesium chlorite and barium chlorite.76. The wound dressing of claim 75 , wherein the chlorite is added to the absorbent material as a chlorite solution comprising claim 75 , consisting of or consisting essentially of sodium chlorite.77. The wound dressing of claim 70 , wherein the chlorite is added to the absorbent material as a stabilized chlorite solution comprising claim 70 , consisting of or consisting essentially of chlorite claim 70 , chlorate claim 70 , chloride claim 70 , sulfate and sodium ions.78. The wound dressing of claim 70 ...

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Номер записи: 76

12-12-2013 дата публикации

Nanocellulose foam containing active ingredients

Номер: US20130330417A1

Автор: Hong Dong, James F. Snyder

Принадлежит: US Department of Army

Nanocellulose foams containing at least one active ingredient and methods of preparing such nanocellulose foams containing one or more active ingredients are provided herein. In some embodiments, a method for preparing nanocellulose foam containing active ingredients may include forming a liquid mixture of nanocellulose, wherein the nanocellulose is at least one of dispersed, suspended or gelled in the liquid mixture; drying the liquid mixture of nanocellulose to form a nanocellulose foam; and mixing at least one active ingredient into at least one of the liquid mixture of nanocellulose or the nanocellulose foam. In some embodiments, a nanocellulose structure may include a nanocellulose foam comprising at least one of a carboxylate group, a hydroxyl group, or a sulfate group bonded to an active ingredient. In some embodiments, the nanocellulose structures are enhanced or crosslinked with metal cations.

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Номер записи: 77

12-12-2013 дата публикации

Odour-Control Superabsorbent

Номер: US20130331260A1

Автор: Olaf Hoeller, Patrick Hamilton, Thomas Daniel, Volker Braig

Принадлежит: BASF SE

Superabsorbents comprising fluorofamide exhibit superior odour control without being biocides.

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Номер записи: 78

19-12-2013 дата публикации

Medical Devices and Implements with Liquid-Impregnated Surfaces

Номер: US20130337027A1

Автор: Adam T. Paxson, Brian R. Solomon, Christopher J. Love, J. David Smith, Kripa K. Varanasi, Rajeev Dhiman

Принадлежит: Massachusetts Institute of Technology

Described herein are medical devices and medical implements with high lubricity to flesh (or biological fluid) and/or inhibited nucleation on its surface. The device has a surface comprising an impregnating liquid and a plurality of micro-scale and/or nano-scale solid features spaced sufficiently close to stably contain the impregnating liquid therebetween. The impregnating liquid fills spaces between said solid features, the surface stably contains the impregnating liquid between the solid features, and the impregnating liquid is substantially held in place between the plurality of solid features regardless of orientation of the surface.

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Номер записи: 79

19-12-2013 дата публикации

Topical Patch For Pain Relief Using Cooling Agent

Номер: US20130337032A1

Автор: Jutaro Shudo

Принадлежит: Teikoku Pharma USA Inc

Topical patch preparations that contain an odorless physiological cooling agent, and methods for using the same are provided. The subject topical patch preparations are made up of an adhesive gel composition that is present on a support, where the adhesive gel composition includes the odorless physiological cooling agent, a water-soluble polymer gel, water and a water holding agent. In using the subject topical patch preparations, the topical patch preparations are applied to a skin surface of a subject and maintained at the site of application for a period of time sufficient for an effective amount of the an odorless physiological cooling agent to be administered to the subject. The subject invention finds use in a variety of applications.

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Номер записи: 80

19-12-2013 дата публикации

Nitric oxide-releasing compositions and methods

Номер: US20130337033A1

Автор: Alysia Lowe, Dennis W. Smith, Jr., Kenneth J. Balkus, Jr., Wenjin Deng

Принадлежит: University of Texas System

The invention relates to nitric oxide-releasing compositions comprising polyacrylonitrile polymers that are diazeniumdiolated, and to medical devices comprising such compositions, as well as to methods of making and using the compositions and medical devices.

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Номер записи: 81

19-12-2013 дата публикации

HEMOSTATIC COMPOSITIONS AND THERAPEUTIC REGIMENS

Номер: US20130337037A1

Автор: Finkielsztein Sergio, Voumakis John N.

Принадлежит: Marine Polymer Technologies, Inc.

The present invention relates generally to the field of hemostasis, including methods, compositions, and devices that can be employed to treat wounds. More specifically the present invention relates to hemostatic compositions that reduce the need for, and cost of, nursing care of patients with chronic wounds by reducing the frequency of wound dressing changes. 1. A poly-β-1→4-N-acetylglucosamine composition comprising biocompatible poly-β-1→4-N-acetylglucosamine fibers , wherein (i) the majority of the fibers are less than about 15 μm in length , and (ii) the composition (a) increases metabolic rate of serum-starved human umbilical cord vein endothelial cells in a MTT assay and/or does not rescue apoptosis of serum-starved human umbilical cord vein endothelial cells in a trypan blue exclusion test , and (b) is non-reactive when tested in an intramuscular implantation test.2. The composition according to claim 1 , wherein the composition increases metabolic rate of serum-starved human umbilical cord vein endothelial cells in a MTT assay and does not rescue apoptosis of serum-starved human umbilical cord vein endothelial cells in a trypan blue exclusion test.3. The composition according to claim 1 , wherein the majority of the fibers have a thickness or diameter of about 1-2 μm.4. The composition according to claim 1 , wherein at least 50% of the fibers are about 4 μm in length.6. The method according to claim 5 , further comprising:(b) repeating said application every 5 to 35 days.7. The method according to or claim 5 , wherein the wound is a chronic wound.8. The method according to claim 7 , wherein the chronic wound is a diabetic ulcer claim 7 , a venous stasis ulcer claim 7 , an arterial insufficiency ulcer claim 7 , or a pressure ulcer.9. The method according to claim 8 , wherein the chronic wound is a venous stasis ulcer.10. The method according to or claim 8 , wherein the wound is a surgical wound or a burn wound.11. A method for producing a poly-β-1→4-N- ...

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Номер записи: 82

02-01-2014 дата публикации

Activated Leukocyte Composition and Uses For Wound Healing

Номер: US20140004091A1

Автор: Adi Zuloff-Shani, Eilat Bain, Eilat Shinar, Irene GILLIS, Marina Bubis, Mitchell Shirvan, Orit Frenkel

Принадлежит: Macrocure Ltd

Disclosed are therapeutic, blood-derived activated leukocyte compositions, methods of making them, and methods of using the compositions to repair or promote the prevention and healing of wounds.

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Номер записи: 83

02-01-2014 дата публикации

WOUND CARE ARTICLES

Номер: US20140005616A1

Автор: Ashworth Jamie, HUCKFELDT ROGER EUGENE, LOPEZ ANTHONY B., MORELAND JEFFREY, ROSS DION, THOMPSON Eric, ZEDALIS MICHAEL

Принадлежит: ANSELL LIMITED

Single layer and multi-layer anti-microbial wound care fabrics, gloves, sleeves, anklets, socks, finger cots, masks, and similar wound care articles are disclosed. 1. A wound care article , comprising:a knitted first layer comprising a first yarn, the yarn comprising an elastic yarn; anda knitted second layer comprising a second yarn, the second yarn being a hydrophilic yarn including an antimicrobial agent, wherein the second yarn promotes the wicking of moisture to the first layer and the transport of an antimicrobial agent to a wound.2. The wound care article of claim 1 , wherein the first yarn comprises cotton claim 1 , polyesters claim 1 , nylons claim 1 , SPANDEX® claim 1 , LYCRA® claim 1 , or any combination or blend thereof.3. The wound care article of claim 1 , wherein the first yarn comprises a hydrophilic yarn.4. The wound care article of claim 3 , wherein the second layer comprises a nylon yarn.5. The wound care article of claim 4 , wherein the nylon yarn comprises nylon 6 claim 4 , nylon 6 claim 4 ,6 or a Nilit® AQUARIUS yarn.6. The wound care article of claim 1 , wherein the first layer comprises an outer layer and the second layer comprises a skin-contacting inner layer.7. The wound care article of claim 1 , wherein the antimicrobial agent is at least one of gold claim 1 , copper claim 1 , iodine claim 1 , silver claim 1 , or zinc or their alloys claim 1 , a noble metal-ion claim 1 , TRIOSYN® claim 1 , triclosan claim 1 , 2-propanol claim 1 , n-halamines claim 1 , polymeric biguanides claim 1 , quaternary ammonium compounds claim 1 , chlorhexidine gluconate claim 1 , silver-zinc and silver-copper zeolites claim 1 , or compounds and combinations thereof.8. The wound care article of claim 1 , wherein the article is one of an anklet claim 1 , a sock claim 1 , a glove claim 1 , a mask claim 1 , a fingercot claim 1 , a sleeve claim 1 , a compression sleeve claim 1 , an elbow support claim 1 , or a knee support.9. The wound care article of claim 1 , further ...

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Номер записи: 84

23-01-2014 дата публикации

Antimicrobial and immunostimulatory system comprising an oxidoreductase enzyme

Номер: US20140023597A1

Автор: James Joseph Brennan, John Reginald Barrett, Thomas Patrick Patton

Принадлежит: INSTITUTE OF Tech SLIGO

The present invention relates to an antimicrobial and immunostimulatory system, applications thereof and a process for the production of the antimicrobial and immunostimulatory system. The present invention provides a storage-stable antimicrobial and immunostimulatory system comprising an oxidoreductase enzyme, a substrate for the oxidoreductase enzyme and hydrogen peroxide in an aqueous solution wherein the substrate for the oxidoreductase enzyme is present up to 90% by weight and water is present up to 20% by weight based on the weight of the total composition; the system has a pH from approximately 4 to 8; and the system provides a two-stage hydrogen peroxide release.

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Номер записи: 85

13-02-2014 дата публикации

WOUND DRESSING WITH BACTERIOSTASIS AND HYGROSCOPICITY

Номер: US20140044758A1

Автор: Lv Qiulan, MO Xiaohui, Wang Xiaodong, Wu Zhenjun, Zhang Dawei

Принадлежит:

A wound dressing with bacteriostatic and hygroscopicity, preparation method therefore, and the use thereof in preparing a product for treating chronic wounds. The dressing comprises chitosan fiber and modified cellulose fiber. 1. A wound dressing comprising chemically chitosan fibers and chemically modified cellulose fibers , wherein the wound dressing is manufactured by blending of the two fibers through nonwoven process and fiber linear density is between 0.5-5 dtex , fiber length is between 10-125 mm.2. (canceled)3. The wound dressing as claimed in claim 1 , wherein the chitosan fibers are non-chemically-modified chitosan fibers having an average absorbency of 100%-500% of solution containing 8.298 g sodium chloride and 0.368 g calcium chloride dihydrate per liter.4. The wound dressing as claimed in claim 1 , wherein the wound dressing has an average wet strength of 0.3-6 N/cm.5. The wound dressing as claimed in claim 3 , wherein the wound dressing comprises 5-95% by weight of chemically modified or unmodified chitosan fibers claim 3 , 95-5% by weight of chemically modified cellulose fibers.67-. (canceled)8. The wound dressing as claimed in claim 1 , wherein the chemically modified or unmodified chitosan fibers and chemically modified cellulose fibers contain surfactant claim 1 , or antimicrobial agent or their combinations.9. The wound dressing as claimed in claim 1 , wherein the degree of deacetylation of chitosan fibers are above 50% claim 1 , preferably above 70%.10. (canceled)11. The wound dressing as claimed in claim 1 , wherein the chemically modified cellulose fibers are carboxymethyl cellulose fibers claim 1 , preferably carboxymethyl solvent spun cellulose fibers.12. The wound dressing as claimed in claim 1 , wherein the chemically modified cellulose fibers are sulfonated cellulose fibers claim 1 , preferably sulfonated solvent spun cellulose fibers.13. The wound dressing as claimed in claim 1 , wherein the wound dressing is a nonwoven felt claim 1 , ...

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Номер записи: 86

13-02-2014 дата публикации

FAST-CLOTTING WOUND DRESSINGS

Номер: US20140046277A1

Автор: Farrell David Henry

Принадлежит:

Disclosed herein are fast-clotting wound dressings impregnated with one or more hemostatic agents including, for example, tissue factor, and optionally, one or more phospholipids. Such dressings may be used to initiate blood clotting on a wound of a subject. 1. A fast-clotting wound dressing impregnated with tissue factor and/or analogues , homologues , precursors or derivatives thereof.2. The fast-clotting wound dressing of claim 1 , further comprising one or more phospholipids impregnated within said dressing.3. The fast-clotting wound dressing of wherein said one or more phospholipids are phosphatidylcholine claim 2 , phosphatidylserine and/or sphingomyelin.4. The fast-clotting wound dressing of claim 1 , wherein the tissue factor is human tissue factor.5. The fast-clotting wound dressing of claim 4 , wherein the human tissue factor is produced using recombinant technology.6. The fast-clotting wound dressing of claim 1 , wherein said wound dressing initiates clotting within 120 seconds of application to a wound.7. The fast-clotting wound dressing of claim 1 , wherein said wound dressing initiates clotting within 27 seconds of application to a wound.8. The fast-clotting wound dressing of claim 1 , wherein tissue factor is impregnated at a concentration of 5 pmoles-100 pmoles per bandage.9. The fast-clotting wound dressing of claim 1 , wherein the dressing is further impregnated with a secondary clotting factor.10. The fast-clotting wound dressing of claim 1 , wherein the dressing is further impregnated with one or more secondary agents selected from the group consisting of pharmaceuticals claim 1 , antifungal agents claim 1 , topical pain reducing medication claim 1 , pharmaceuticals claim 1 , anti-inflammatory agents and tissue enzyme inhibitors.11. The fast-clotting wound dressing of claim 10 , wherein the pharmaceutical is an analgesic claim 10 , an anti-inflammatory agent claim 10 , or an antibacterial.12. A fast-clotting wound dressing impregnated with one or ...

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Номер записи: 87

20-02-2014 дата публикации

Article Comprising Calcium for Reducing the Production of TSST-1

Номер: US20140048075A1

Автор: Davis Catherine Cornick, Nemeth Kimberly Ann, Osborn Thomas Ward, Wang Fancheng

Принадлежит: The Procter & Gamble Company

Articles comprising one or more calcium salts are provided. The articles can contain one or more calcium salts in an amount effective to reduce the production of TSST-1 by at least about 50% when measured by the Shake Flask Method. In certain embodiments, the one or more calcium salts can be substantially non-lethal to when measured by the Shake Flask Method, and/or to , and/or when measured by the Maximum Tolerated Dose Test. 1. A vaginal article , comprising:a. a primary absorbent member;b. an overwrap covering at least a portion of the primary absorbent member;c. an optional secondary absorbent member situated proximate a withdrawal end of the primary absorbent member; andd. a withdrawal cord attached to and extending from the primary absorbent member;e. wherein at least one of the overwrap, the optional secondary absorbent member, and the withdrawal cord comprises one or more calcium salts in an amount greater than about 0.009 millimoles of calcium to reduce the production of TSST-1 by at least about 50% when measured by the Shake Flask Method; and{'i': Lactobacillus crispatus, Lactobacillus gasseri', 'Lactobacillus iners, 'f. wherein the one or more calcium salts are substantially non-lethal to , and when measured by the Maximum Tolerated Dose Test.'}2. The vaginal article of claim 1 , wherein the one or more calcium salts are calcium lactate and/or calcium citrate malate.3. The vaginal article of claim 1 , wherein the overwrap comprises the one or more calcium salts.4. The vaginal article of claim 1 , wherein the vaginal article is a tampon.5. The vaginal article of claim 1 , wherein the vaginal article is a pessary.6. A method for manufacturing a vaginal article claim 1 , the method comprising the steps of:a. providing a tampon pledget;b. adding one or more calcium salts to the tampon pledget;c. compressing and/or shaping the tampon pledget into a finished tampon configuration that is different than that of the tampon pledget;d. wherein the one or more ...

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Номер записи: 88

20-02-2014 дата публикации

Hemostatic compositions and therapeutic regimens

Номер: US20140051849A1

Автор: John N. Voumakls, Sergio Finkielsztein

Принадлежит: Marine Polymer Technologies Inc

The present invention relates generally to the field of hemostasis, including methods, compositions, and devices that can be employed to treat wounds. More specifically the present invention relates to hemostatic compositions that reduce the need for, and cost of, nursing care of patients with chronic wounds by reducing the frequency of wound dressing changes.

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Номер записи: 89

06-03-2014 дата публикации

Reactive Oxidative Species Generating Materials and Methods of Use

Номер: US20140065090A1

Автор: Brown Tiffany J., Lafleur Adam S., Mazich Kenneth, Towler Jeffrey C., ZHANG Ji

Принадлежит: W. L. Gore & Associates, Inc.

Materials capable of delivering stabilized free radicals to targeted treatment sites. The materials comprise semi-crystalline, hydrolytically degradable polymers that are subjected to ionizing radiation to create stabilized free radicals therein. Upon exposure to oxygen containing aqueous media, the materials generate reactive oxidative species which are useful in biological processes. 1. A biocompatible material comprising at least one semi-crystalline , hydrolytically degradable polymer wherein the polymer has been subjected to ionizing radiation at a total dose from about 30 kGy to about 50 kGy and wherein the biocompatible material comprises stabilized free radicals.2. The biocompatible material of wherein upon contacting the biocompatible material with aqueous media the stabilized free radicals enable the production of reactive oxidative species over an extended period of time.3. The biocompatible material of wherein the specific surface area per unit area of the biocompatible material is from about 0.001 m2/gm to about 50 m2/gm4. The biocompatible material of wherein the polymer is subjected to ionizing radiation at a total dose rate of from about 40 kGy to about 50 kGy.5. The biocompatible material of wherein the polymer is bioabsorbable.6. The biocompatible material of wherein the polymer is selected from the group consisting of poly(dioxanone) claim 5 , poly(glycolide) claim 5 , poly(lactide) poly(ε-caprolactone) claim 5 , poly(anhydrides) such as poly(sebacic acid) claim 5 , poly(hydroxyalkanoates) such as poly(3-hydroxybutyrate) claim 5 , copolymers of any of these and combinations thereof.7. The biocompatible material of wherein said reactive oxidative species are selected from the group consisting of superoxide claim 2 , hydrogen peroxide claim 2 , singlet oxygen claim 2 , hydroxyl radical claim 2 , perhydroxy radical claim 2 , peroxynitrite claim 2 , hypochlorite claim 2 , and combinations thereof.8. The biocompatible material of further comprising a ...

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Номер записи: 90

20-03-2014 дата публикации

ANTIOXIDANT AND ANTIMICROBIAL WOUND DRESSING MATERIALS

Номер: US20140079805A1

Автор: Addison Deborah, Cullen Breda Mary, Greenhalgh David

Принадлежит: SYSTAGENIX WOUND MANAGEMENT (US), INC.

A wound dressing material comprising a polymeric substrate, a silver salt, and a dyestuff to photostabilize the silver salt. The substrate may comprise collagen and/or oxidized regenerated cellulose complexed to Ag, and the dyestuff may for example be an aniline or acridine dye. 1. A wound dressing material comprising a polymeric substrate , a silver salt , and a dyestuff to photostabilize the silver salt.219-. (canceled) The present invention relates to antimicrobial wound dressing materials, to processes suitable for the preparation of such materials, and to the use of such materials in the manufacture of wound dressings.The antimicrobial effect of silver has been known for centuries. However, the precise mode of action of silver salts in killing microbes is yet to be established. It is known that silver salts bind with particular avidity to DNA and RNA. Silver salts also bind with particular strength to a variety of organic molecules such as: carboxylic acids, thiols, phenols, amines, phosphates and halogenated compounds. Following binding to proteins, those with enzymic activity are usually deactivated. The oxidative-reductive powers of silver and silver salts must also be reckoned with.It is known to use metallic silver as an antimicrobial, whether in the form of thin films, nanoparticles or colloidal silver. Chemical compounds of silver are also useful as antimicrobials. For example, the following complex silver salts are favoured for use against sensitive and resistant bacterial strains:WO91/11206 describes the use of silver alginate salts in wound dressings. WO87/05517 describes silver salts of hyaluronic acid that may be used as or in antimicrobial wound dressings. These materials tend not to be stable in the presence of light. The silver undergoes photochemical reduction to metallic silver, causing a darkening of the materials over time.WO02/43743 describes light-stabilized antimicrobial wound dressing materials in which silver salts are stabilized by the ...

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Номер записи: 91

27-03-2014 дата публикации

Transdermal Therapeutic System Provided With Improved Long-Term Carrying Comfort

Номер: US20140086978A1

Автор: Lothar Deurer, Thomas Hille

Принадлежит: LTS Lohmann Therapie Systeme AG

The invention relates to transdermal therapeutic systems (TTS) comprising a backing, a reservoir layer containing at least one pharmaceutical active ingredient, and an adhesive. Said transdermal therapeutic systems are characterised in that they are able to continuously adhere to the surface of the skin over a long period of time. During said long period of time, a) there is at least one time interval during which the TTS adhering to the surface of the skin is intensively exposed to water, and b) the active ingredient is transdermally released. The invention also relates to a method for the continuous transdermal release of at least one pharmaceutical active ingredient over a long period of time.

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Номер записи: 92

10-04-2014 дата публикации

COMPOSITES CONTAINING POLYPEPTIDES ATTACHED TO POLYSACCHARIDES AND MOLECULES

Номер: US20140099444A1

Автор: Catchmark Jeffrey M., Mears Dana Meredith, Mishra Niharika, Siggins John

Принадлежит: THE PENN STATE RESEARCH FOUNDATION

This document provides methods and materials related to composites or coatings containing polypeptides attached to polysaccharides and/or molecules. For example, methods and materials related to composites or coatings containing polypeptides (e.g., casein polypeptides) attached to polysaccharides (e.g., cellulose) and/or molecules (e.g., calcium containing molecules such as calcium phosphate and calcium carbonate and/or polyesters such as polylactic acid and polyhydroxybutyrate) are provided. A coating provided herein can include both cationic and ionic polymers, polypeptides, or polysaccharides. 120-. (canceled)21. A method for coating a product , wherein said method comprises:(a) combining casein, a calcium containing mineral, and a biopolymer to form a mixture, and(b) applying said mixture to a product to form a coated product.22. The method of claim 21 , wherein said calcium containing mineral is calcium carbonate.23. The method of claim 21 , wherein said calcium containing mineral is calcium phosphate.24. The method of claim 21 , wherein said biopolymer comprises polylactic acid.25. The method of claim 21 , wherein said biopolymer comprises poly(lactic-co-glycolic) acid.26. The method of claim 21 , wherein said step (a) comprises mixing said casein and said calcium containing mineral in water.27. The method of claim 21 , wherein said step (a) comprises mixing said casein and said calcium containing mineral in water having a pH of 7-11.28. The method of claim 21 , wherein said step (a) comprises mixing said casein and said calcium containing mineral in solution claim 21 , wherein the solid content of said solution is from 0.5 percent to 5 percent.29. The method of claim 21 , wherein said step (a) comprises (i) mixing said casein and said calcium containing mineral in solution and (ii) adding said biopolymer to said solution.30. The method of claim 21 , wherein said mixture is applied to said product using a gravure coating process.31. The method of claim 21 , ...

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Номер записи: 93

06-01-2022 дата публикации

SYNTHETIC ANTIMICROBIAL MINERAL COMPOSITIONS, METHODS OF MAKING AND USING SAME

Номер: US20220000912A1

Автор: Loots Gabriela G., Martin Kelly Anne, Morrison Keith David, Samo Ty James

Принадлежит:

Provided herein are pharmaceutical compositions comprising a Fe-exchanged fluorinated synthetic smectite and a synthetic semiconducting metal sulfide. The compositions can be used to treat topical conditions and gastrointestinal ailments, and can be incorporated into wound dressings, hydrogels, personal protective equipment, and 3D printed articles. Also provided are methods of synthesizing the Fe-exchanged fluorinated synthetic smectite and methods of making the synthetic semiconducting metal sulfide. 1. A pharmaceutical composition comprising Fe-exchanged fluorinated synthetic smectite and synthetic semiconducting metal sulfide.2. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite is present in an amount of 80 wt % to 98.5 wt % claim 1 , based on the total weight of the composition and wherein the synthetic semiconductinq metal sulfide is present in an amount of 1.5 wt % to 20 wt % based on the total weight of the composition.3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite claim 1 , at an octahedral site claim 1 , comprises Li.11. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite claim 1 , at an octahedral site claim 1 , comprises Mg claim 1 , Cu claim 1 , Zn claim 1 , or Fe.12. (canceled)13. The composition of claim 1 , wherein the Fe-exchanged fluorinated synthetic smectite comprises from 5 meq to 100 meq of ferrous iron (Fe) claim 1 , per 100 g of the Fe-exchanged fluorinated synthetic smectite.14. (canceled)15. (canceled)16. The composition of claim 1 , free of arsenic claim 1 , lead claim 1 , cobalt claim 1 , nickel claim 1 , mercury claim 1 , or uranium.17. The composition of claim 1 , wherein the semiconducting metal sulfide comprises one or more of synthetic pyrite claim 1 , synthetic acanthite claim 1 , synthetic chalcocite claim 1 , synthetic bornite claim ...

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Номер записи: 94

02-01-2020 дата публикации

BIOMEDICAL PATCHES WITH ALIGNED FIBERS

Номер: US20200000570A1

Автор: MacEwan Matthew R., Ray Zack, Xia Younan, Xie Jingwei

Принадлежит:

A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a flexible deposited fiber network of varying density including a first and second set of set of electrospun fibers. The second set of electrospun fibers is coupled to the first. A first portion of the flexible deposited fiber network includes a higher density of fibers than a second portion of the flexible deposited fiber network, and the tensile strength of first portion is higher than that of the second portion. The scaffold is sufficiently flexible to facilitate application of scaffold to uneven surfaces of the tissue substrate, and enables movement of the scaffold by the tissue substrate. The first and second set of fibers are configured to degrade within three months after application, and each fiber of the deposited fiber network has a diameter of 1-1000 nanometers. 1. A three-dimensional electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate , the three-dimensional electrospun nanofiber scaffold comprising: a first set of electrospun fibers comprising a first bioresorbable polymer, wherein the first bioresorbable polymer comprises polyglycolic acid; and', 'a second set of electrospun fibers comprising a second bioresorbable polymer, the second set of fibers coupled to the first set of fibers,', 'wherein the first bioresorbable polymer comprises a different composition from the second bioresorbable polymer,, 'a flexible deposited fiber network of varying density, the deposited fiber network comprisingwherein a first portion of the flexible deposited fiber network comprises a higher density of fibers than a second portion of the flexible deposited fiber network, and wherein the first portion comprises a higher tensile strength than the second portion;wherein the three-dimensional electrospun nanofiber scaffold is sufficiently flexible to facilitate application of the three-dimensional electrospun ...

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Номер записи: 95

03-01-2019 дата публикации

ABSORBENT SHEET

Номер: US20190000676A1

Автор: KAWAGUCHI Asami, SAITO Yuko, SHIRAI Ayako, SUGAYA Mariko, YAEZAWA Takashi

Принадлежит:

The purpose of the present invention is to provide an absorbent sheet capable of sufficiently absorbing exudates exuding from an area of a lesion and exhibiting a powerful deodorizing effect for illness-associated odors. The invention relates to an absorbent sheet with deodorizing functions having an absorbent region and a deodorizing region situated to at least one side of the absorbent region, wherein the absorbent region contains cellulosic fibers, an absorbent polymer and a thermal adhesive resin, and the deodorizing region contains cellulosic fibers, a deodorizing agent and a thermal adhesive resin. 1. An absorbent sheet with deodorizing functions having an absorbent region and a deodorizing region situated to at least one side of the absorbent region , wherein:the absorbent region contains cellulosic fibers, an absorbent polymer and a thermal adhesive resin, andthe deodorizing region contains cellulosic fibers, a deodorizing agent and a thermal adhesive resin.2. The absorbent sheet with deodorizing functions according to claim 1 , wherein the absorbent polymer is absorbent fibers.3. The absorbent sheet with deodorizing functions according to claim 1 , wherein the content of the absorbent polymer is 10 to 50% by mass relative to the total mass of the solid content constituting the absorbent region.4. The absorbent sheet with deodorizing functions according to claim 1 , wherein the absorbent polymer contains a sodium polyacrylate resin.5. The absorbent sheet with deodorizing functions according to claim 1 , wherein the deodorizing agent contains a component that reacts with at least one selected from sulfides claim 1 , sulfurs and amines.6. The absorbent sheet with deodorizing functions according to claim 1 , wherein the deodorizing agent contains a polyphenol and a polyphenol oxidase.7. The absorbent sheet with deodorizing functions according to claim 1 , wherein the deodorizing agent contains at least one selected from metals claim 1 , minerals claim 1 , ...

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Номер записи: 96

02-01-2020 дата публикации

Multi-Layer Wound Care Device Having Absorption and Fluid Transfer Properties

Номер: US20200000640A1

Автор: Acevedo Cristina M., Foote Matthew I., Haas Geoffrey R., Mondal Rajib

Принадлежит:

This disclosure relates to a multi-layer wound care device having absorption and fluid transfer properties. The wound care device contains capillary force one-way pumps that are capable of transporting fluid, such as wound exudate, away from a wound site to the opposite side of the wound care device, which functions as a segregated fluid reservoir. This fluid transport mechanism generally aids in reducing wound maceration by removing excess wound fluid and the protease enzymes and infectious bacteria contained within the wound fluid. The wound care device performs this function, often times for multiple days, without the loss of the physical integrity of the wound care device. In addition to providing a uni-directional fluid transport mechanism, the wound care device provides improved absorption properties. 1. A wound care device comprising:a first layer of fabric having a wound contact surface and a wound fluid reservoir surface, wherein the first layer of fabric contains lyocell fibers;a first hotmelt adhesive; anda second layer of fabric;wherein the first hotmelt adhesive is disposed between the first layer of fabric and the second layer of fabric; andwherein the first hotmelt adhesive is disposed on the wound fluid reservoir surface of the first layer of fabric; andwherein the wound care device transports wound fluid uni-directionally from the wound contact surface to the wound fluid reservoir surface upon exposure to a wound.2. The wound care device of claim 1 , wherein the first layer of fabric is knit fabric.3. The wound care device of claim 2 , wherein the knit fabric is circular knit fabric.4. The wound card device of claim 3 , wherein the circular knit fabric is a jersey knit fabric.5. The wound care device of claim 1 , wherein the first layer of fabric is comprised primarily of hydrophobic fibers and hydrophilic fibers.6. The wound care device of claim 5 , wherein the hydrophobic fibers are polyester fibers.7. The wound care device of claim 5 , wherein ...

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Номер записи: 97

02-01-2020 дата публикации

GARMENTS AND ASSOCIATED METHODS

Номер: US20200000649A1

Автор: Griffiths Joanna

Принадлежит:

Garments and associated methods are disclosed. In examples, a garment includes an absorbent assembly bonded to a body portion. In examples, the absorbent assembly includes an absorbent layer and overlies at least a central region of the body portion. In examples, the absorbent assembly is at least partially bonded to the body portion with elastic bonding film. In examples, the garment is configured to be washed and re-worn numerous times. In examples, a method of manufacturing a garment includes arranging an absorbent assembly over at least the central region of the body portion and bonding the absorbent assembly to the body portion with strips of elastic bonding film and without stitching. In examples, a moisture-absorbent garment includes a body layer supporting an absorbent assembly within a central region and strips of elastic bonding film that bond at least a portion of the absorbent assembly to the body layer without stitching. 2. The garment of claim 1 , wherein the garment includes strips of the elastic bonding film claim 1 , and wherein at least a portion of the absorbent assembly is positioned between one or more of the strips of the elastic bonding film and the body portion.3. The garment of claim 2 , wherein the absorbent assembly includes a plurality of layers claim 2 , and wherein at least a portion of each layer is positioned between one or more of the strips of the elastic bonding film and the body portion.4. The garment of claim 2 , wherein two or more of the strips of the elastic bonding film are positioned in respective portions of a peripheral region of the absorbent assembly on opposite sides of the central5. The garment of claim 1 , further comprising a moisture-barrier layer at least partially positioned between the two opening regions.6. The garment of claim 5 , wherein at least a portion of the moisture-barrier layer extends between the elastic bonding film and the absorbent layer.7. The garment of claim 5 , wherein the absorbent layer and ...

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Номер записи: 98

04-01-2018 дата публикации

ABSORBENT ARTICLE

Номер: US20180000663A1

Автор: Ishida Hidenobu, Nishida Mitsuo

Принадлежит:

Provided is an absorbent article having excellent shape retention of an absorber even when an external force is applied thereto. The present invention is an absorbent article having: an aqueous-liquid absorbing part having crosslinked polymer particles having as essential constitutional units thereof a water-soluble vinyl monomer and/or a vinyl monomer which became the water-soluble vinyl monomer by hydrolysis, and a crosslinking agent; and a nonwoven fabric having porous fibers as an essential constituent thereof, the crosslinked polymer particles preferably absorbing 40 times the weight thereof of physiological saline 40 in 40-150 seconds. 1. An absorbent article comprising:{'b': 1', '2', '1', '3, 'an aqueous-liquid absorbing part that contains crosslinked polymer particles (A) comprising a water-soluble vinyl monomer (a) and/or a vinyl monomer (a) that turns into a water-soluble vinyl monomer (a) through hydrolysis, and a crosslinking agent (a) as essential constitutional units; and'}{'b': '1', 'a nonwoven fabric (B) comprising porous fibers (b) as an essential constituent.'}2. The absorbent article according to claim 1 , wherein the crosslinked polymer particles (A) are crosslinked polymer particles that absorb physiological saline 40 times their own weight in 40 to 150 seconds.3. The absorbent article according to claim 1 , wherein the crosslinked polymer particles (A) are crosslinked polymer particles having a basic flowability energy measured by a powder flow analyzer of 500 to 8000 mJ.4. The absorbent article according to claim 1 , wherein the aqueous-liquid absorbing part further contains hydrophilic fibers (c).51. The absorbent article according to claim 1 , wherein the porous fibers (b) are formed of an acrylonitrile-based polymer that is formed by polymerizing a monomer composition containing acrylonitrile and has an acrylonitrile content of 70% or more based on the total weight of the monomer composition.61. The absorbent article according to claim 1 , ...

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Номер записи: 99

05-01-2017 дата публикации

Methods for Decontaminating Skin

Номер: US20170000664A1

Автор: Frazier Laura M., Kataphinan Woraphon, Lademann Jurgen

Принадлежит: SNS Nano Fiber Technology, LLC

The present invention provides a method for decontaminating a skin area contaminated with noxious substances by absorbing or capturing the substances, and the method comprises the steps of applying absorbent textile composite material to the contaminated skin area for a predetermined period of time, and removing the absorbent textile composite material from the contaminated skin area. 149-. (canceled)51. The method of claim 50 , wherein the absorbent textile composite material further comprises an adhesive layer on the active layer facing the contaminated skin area.52. The method of claim 50 , further comprising applying a second absorbent textile composite material to the contaminated skin area; whereinthe second absorbent textile composite material comprises an optional carrier layer, an active layer, and an adhesive layer;the active layer is connected with the carrier layer and comprises a nanofiber nonwoven optionally filled with a superabsorbent; andthe adhesive layer is on the active layer facing the contaminated skin area and adheres the absorbent composite material to the contaminated skin area.5350. The method of claim 50 , further comprising stimulating production of sweat in the contaminated skin area claim 50 , wherein the carrier layer is impermeable to water or oil vapor.5450. The method of claim 50 , further comprising stimulating production of sweat in the contaminated skin area claim 50 , wherein at least one of the active layer and the carrier layer is permeable to heat radiation.55. The method of claim 50 , further comprising stimulating production of sweat in the contaminated skin area claim 50 , wherein at least one of an active layer and a carrier layer is heat conducting.56. The method of claim 50 , further comprising stimulating production of sweat in the contaminated skin area claim 50 , wherein an active layer comprises a sweat promoting agent.57. The method of claim 50 , wherein the noxious substances are solid particles claim 50 , an ...

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Номер записи: 100