СПОСОБ ВВОДА РАБОЧИХ КОМАНД В АППАРАТ "ИСКУССТВЕННАЯ ПОЧКА", УСТРОЙСТВО ДЛЯ ВЫПОЛНЕНИЯ ГЕНОДИАЛИЗА

Предложены способы ввода рабочих команд в схему гемодиализа, включающую фильтр для диализа и возможность работы в соответствии с изменяемым по времени параметром, таким, как меняющаяся ультрафильтрация. Согласно этим способам, вводятся значение требуемого периода времени, заданное суммарное значение параметра, такого, как заданный объем ультрафильтрации, и предполагаемый изменяющийся по времени профиль параметра, представляющий собой ряд координат на участке, ограниченном осью ординат, на которой откладываются значения параметра, и осью абсцисс, на которой откладывается время, а график показывает профиль нарастания значения параметра. Если суммарное значение по профилю не равно заданному суммарному значению, изменяется положение предполагаемого изменяющегося по времени профиля относительно оси ординат, чтобы уравнять эти суммарные значения. После этого схема работает согласно измененному профилю, чтобы достичь заданного введенного суммарного значения в течение заданного периода времени.

Gerät zur Peritonealdialyse und Datenträger mit Kontrollverfahren hierfür

FRAME-MOUNTED FLEXIBLE CONTAINER

Frame-mounted flexible container

A flexible container 100, Fig. 2, in which a liquid may be stored or through which a liquid may be circulated is received by a frame 80, Fig. 10 having a cross member 81 from which extends a pair of substantially parallel arm elements 82a 82b. The container comprises a pair of walls including two relative thin, generally flexible sheets of a polymeric material, a top edge, 110, a bottom edge 112, a centrally located compartment for containing said liquid, an elongated sleeve adjoining each side edge of said compartment, an inlet, 121, for introducing said liquid into said compartment and an outlet 122 for withdrawing said liquid from said compartment, each of said sleeves having an inner edge 133, 134 and an outer edge 131, 132, the straight-line distance between the outer edges of said sleeves being greater along the top edge of the container than the straight-line distance between the outer edges of said sleeves along the bottom edge of said container, so that the bottom edge is under ...

Modular home dialysis system - debubblers

An apparatus for removing air bubbles from blood is disclosed. The debubbler comprises front and rear covers (1002, 1008 respectively) with a fluid circuit board (1004) arranged between the two covers. A blood chamber is defined between cover (1002) and circuit board (1004) and an air chamber is defined between covers (1008) and circuit board (1004). A microporous membrane (1006) separates the blood and air chambers. A support means (1024) supports membrane (1006) from the air side of the membrane. A blood pressure sensor is provided between covers (1002, 1008). The debubbler has a blood inlet port (1022) and a blood outlet port (1020) for conducting blood to and from the blood chamber. An air port (1012) is provided in communication with the air chamber, to allow air passing through membrane (1006) to escape.

Modular home dialysis system

BLOOD TREATMENT EQUIPMENT

EQUIPMENT TO PERITONEALDIALYSE AND DATA MEDIA WITH INSPECTION PROCEDURES FOR THIS

SYSTEM FOR THE PERITONEALDIALYSE

SYSTEM AND PROCEDURE FOR MANUFACTURING STERILE, MIXED SOLUTIONS FOR THE AUTOMATIC PERITONEALDIALYSE

Portable dialysis machine

H:\mhiutewovn\N~orbf\CC\MH56030_Lducx-1/03j2(08 The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface, a heater in thermal communication with the planar surface, and a sodium sensor in electromagnetic communication with the planar surface. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features. WO 2012/108910 PCT/US2011/053184 201 211 210 ...

Device and method for producing a peritoneal dialysis solution

The invention relates to a device for producing a peritoneal dialysis solution at the place of use comprising a disposable with a solution bag and filling lines and patient lines connected thereto, a provision unit for liquid, said provision unit being connected to the filling line, a control unit and actuators for regulating a flow from the provision unit to the disposable, wherein the device further comprises a scale on which the solution bag of the disposable is arranged, and wherein the control unit is designed to cause, by means of the actuators, the provision unit to fill the solution bag with liquid and to determine, by means of the scale, the amount of fluid that has flowed into the solution bag.

Container for fluids and apparatus for temperature control, e.g. warming, of medical fluids

A container for warming fluids, the container comprising an inlet port, an outlet port, and a fluid conduit configured for putting the inlet port in fluid communication with the outlet port and comprising one or more deflection sections. The fluid conduit has a non-constant maximum width in a direction of fluid flow through the fluid conduit. At least one of the one or more deflection sections further comprises an entry section and an exit section, each respective exit section being arranged downstream, in the direction of fluid flow, from each respective entry section. The maximum width of the fluid conduit decreases along the direction of fluid flow through the entry section over a first distance and the maximum width of the fluid conduit increases along the direction of fluid flow through the exit section over a second distance, the first distance and the second distance being different from one another. An apparatus for warming medical fluids including the container and an extracorporeal ...

ELECTRICAL SYSTEMS, METHODS AND APPARATUSES FOR AN AUTOMATED DIALYSIS MACHINE

Self-warming peritoneal dialysis solution bag

A self-warming peritoneal dialysis solution bag (20) is provided that contains a peritoneal dialysis solution. The solution bag (20) can have an outer surface and a non-electric, warming patch (32, 34) adhered or affixed to the outer surface. The non-electric, warming patch (32, 34) can include an activatable agent that undergoes an exothermic reaction when activated. The warming patch (32, 34) can retain a sufficient amount of activatable agent to generate enough heat, upon activation, to warm the contents of the bag (20) to at least 95°F. Warming patches that are separate from a peritoneal dialysis solution bag are also provided, as are kits for warming a peritoneal dialysis solution bag. Methods of warming a peritoneal dialysis solution bag with a non-electric, warming patch, are also provided.

BLOOD TREATMENT SYSTEMS AND METHODS

A dialysis system, comprising: a chamber including a membrane that is movable in the chamber and that fluidly separates a first portion of the chamber from a second portion of the chamber, the chamber including a first inlet to the first portion and a second inlet to the second portion; and a blood leak sensor associated with the chamber and arranged to detect blood in the first portion of the chamber, wherein the blood leak sensor is arranged to measure a first level in the first portion and a second level in the second portion for comparison of the first and second levels to each other to determine whether blood is present in the first portion.

Hose adapter for influencing the pressure inside a hose section during a medical treatment

The present invention relates to a hose adapter for connection to at least one hose section of a medical device. The invention further relates to a dialysate hose system having such a hose adapter, to a medical device having such a dialysate hose system, to a method for using the hose adapter according to the invention and to a method for preventing the occurrence of a pressure below a minimum pressure in a dialysate hose system.

Apparatuses and processes for whole-body hyperthermia

HEMOFILTRATION DEVICE TO INDEPENDENTLY CONTROL THE CONCENTRATION OF AT LEAST TWO IONIC SUBSTANCES IN THE PATIENT'S INTERNAL ENVIRONMENT

Un appareil d'hémofiltration comporte: - des moyens (20, 24, 34, 38) pour préparer une première solution injectable à partir d'au moins une solution concentrée; - des moyens (33) pour injecter, à un débit d'injection Qpre, la première solution dans la canalisation (5) de prélèvement de sang d'un circuit de circulation extracorporelle de sang (2, 5, 7, 8); - des moyens (50, 51, 52, 53) pour perfuser à un patient une deuxième solution contenant au moins une substance ionique A ayant une concentration déterminée [A]post différente de la concentration [A]pre de cette substance A dans la première solution; - des moyens (60) pour déterminer un débit de perfusion Qpost de la deuxième solution pour que la concentration de la substance A dans le milieu intérieur du patient tende vers une concentration souhaitée [A]des, en fonction de la concentration (A]post de la substance A dans la deuxième solution, de la concentration souhaitée [A] des, du débit d' injection Qpre de la première solution, et ...

APPARATUSES AND PROCESSES FOR WHOLE-BODY HYPERTHERMIA

Apparatuses for use in whole-body hypothermia include a high-flow hyperthermia circuit coupled to a low-flow dialysis circuit in a manner which reduces tensioning of membranes in the dialyzer (152) of the dialysis circuit. The arrangement thereby allows proper membrane movement to assist in mixing a sorbent suspension (176) circulated on the sorbent side of the dialyzer. Additional dialysis apparatuses include advantageous disposable packs (300) including the dialyzer (152), sorbent heat exchangers (186) arranged to cooperate with heating elements on base units of the apparatuses, and adaptations for very high flow rates useful in the hyperthermic treatment of cancers.

PERSONAL HEMODIALYSIS SYSTEM

A dialysis machine includes a dialysis instrument having a pump actuator and first and second valve actuators, and a disposable cassette operable with the dialysis instrument, the disposable cassette including a pump portion operable with the pump actuator, first and second valve chambers operable with the first and second valve actuators, the first and second valve chambers communicating fluidly with each other, at least the first valve chamber communicating fluidly with a compliance chamber, the compliance chamber negating a first backpressure due to a pneumatic closing pressure used to close the first valve chamber to help to ensure the pneumatic pressure applied to the first valve chamber will close the first valve chamber against a second backpressure from an existing closure of the second valve chamber.

DIALYSIS PROCESS AND APPARATUS FOR ISOLATION OF THERAPEUTICALLY ACTIVE SUBSTANCES

DIALYSATE BAG HEATER TRAY FOR PERITONEAL DIALYSIS SYSTEMS

In one aspect, a peritoneal dialysis system (100) includes a tray (116) for supporting a bag (124) that can receive dialysate from a source (122) of dialysate, multiple force sensors (218) disposed adjacent a portion (202) of the tray (116) that is in contact with the bag (124) when the bag (124) is supported by the tray (116), and one or more processors configured to receive data from the multiple force sensors (218) and to determine, based on the data, an amount of dialysate contained in the bag (124).

PUMP CASSETTE AND METHODS FOR USE IN MEDICAL TREATMENT SYSTEM USING A PLURALITY OF FLUID LINES

METHODS AND SYSTEMS FOR MEASURING AND HEATING DIALYSATE

The present specification provides a dialysate management system for generating, weighing, and heating a dialysate fluid during a dialysis treatment. The dialysate management system includes a container and base enclosure. A bottom surface of the container rests within the base enclosure, which is configured to weigh the fluid in the container and measure its conductivity. The fluid may be heated using a heater integrated into the base enclosure or positioned in-line with a fluid pathway. The base of the container is preferably sloped and positioned within the internal volume of the container is a disposable prescription bag having a predefined quantity of prescription compositions that dissolve when water is poured into the container.

PORTABLE DIALYSIS MACHINE

SYSTEMS AND METHODS FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION USING WATER ACCUMULATOR AND DISPOSABLE SET

A peritoneal dialysis system includes a water purifier, a cycler, and a disposable set operable with the cycler. The disposable set includes a pumping cassette including a water inlet port, a heater/mixing container in fluid communication with the pumping cassette, a water accumulator, a first water line segment, and a second water line segment. The first water line segment is in fluid communication with the water inlet port and the water accumulator. Additionally, the second water line segment is in fluid communication with the water accumulator and the water purifier.

HYDROPHOBIC FILTERS FOR AIR MANAGEMENT IN DIALYSIS MACHINES

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments, may include a dialysis machine for transferring dialysate to a patient from a dialysate bag, and a warmer pouch for flowing the dialysate through to heat to a predetermined temperature before flowing into the patient. The dialysate may flow from the dialysate bag through the warmer pouch for pumping into the patient via tubing. A filter may be coupled to the warmer pouch, and the filter may be configured to filter out air content from the dialysate.

HYDROPHOBIC FILTERS FOR AIR MANAGEMENT IN DIALYSIS MACHINES

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments, may include a dialysis machine for transferring dialysate to a patient from a dialysate bag, and a warmer pouch for flowing the dialysate through to heat to a predetermined temperature before flowing into the patient. The dialysate may flow from the dialysate bag through the warmer pouch for pumping into the patient via tubing. A filter may be coupled to the warmer pouch, and the filter may be configured to filter out air content from the dialysate.

A SYSTEM AND A METHOD FOR PRODUCING MICROBIOLOGICALLY CONTROLLED FLUID

A method and a system (10a) comprising an integrated water purifying apparatus (110) with a pre-filter circuit (402) including a particle filter and an activated carbon filter arranged to produce pre-treated water; a fluid circuit (404) arranged to receive pre-treated water from the pre-filter circuit (402), the fluid circuit (404) includes an RO-pump (450) and a Reverse Osmosis, RO, device, (301) arranged to produce purified water; a heating device (302) arranged to heat purified water from the RO device (301) to a temperature above 65 °C; the water purifying apparatus (110) is further arranged to heat disinfect the fluid circuit (404) using the heated purified water. The system (1) further comprises a line set (40) connected to the purified water outlet connector (128) at a water line connector (68) of the line set (40), wherein the line set (40) includes at least one sterile sterilizing grade filter (70a, 70b) arranged to filter the purified water into sterile purified water.

Modular Home Dialysis System

MODULAR HOME DIALYSIS SYSTEM

A machine for conducting dialysis of body fluids of a patient. The machine includes integral water preparation and treatment, dialysate preparation, and extracorporeal circuit modules, under computer control from a patient interface and control module. A water pretreatment module with a temperature-controlled mixing valve, an integral water filtration and conditioning unit and a pressure relief with integral water sample removal port supplies water to the machine. The dialysate preparation module includes a substantially non-compliant tank with attached batch chemical bottles and automatic chemical addition and dispersion subsystems. The machine incorporates novel automatic process control techniques to verify the status and integrity of the critical system components, ultrafiltration control, and temperature, pressure and conductivity conditions prior to dialysis.

Dispositif de préparation d'une solution

Device for the treatment of sensitive liquids, especially of blood

The device comprises a closed system for a treatment liquid with which blood is treated by dialysis via semipermeable membranes. This system comprises a heating device (15) for heating the treatment liquid to the purifying and/or sterilising temperature, as well as tubes (4, 5) for connection of a dialyser (1). Heating must not take place when the dialyser is connected to the system. For this reason, a pressure sensor (17) controls the heating device (15) in such a way that heating can only take place when the tubes mentioned are connected not to the dialyser (1) but instead to the pressure sensor (17). This effectively prevents a patient and the closed system during the heating operation from being connected simultaneously to the dialyser. ...

In the course of treating the influence of the pressure in the pipe section of the tube adapter

DIALYSIS OF SUSPENSIONS OF ANIMAL TISSUE

PLANT FOR THE TREATMENT OF BLOOD OR OTHER LIQUIDS ALSO PERISHABLE

PROCEDE DE PREPARATION DE SOLUTION POUR DIALYSE PERITONEALE ET MACHINE POUR SA MISE EN OEUVRE

PROCEDE DE PREPARATION DE SOLUTION STERILE ET APYROGENE UTILISABLE EN MEDECINE. LES ETAPES PRINCIPALES DE CE PROCEDE SONT : A.LA PREPARATION D'UNE SOLUTION TITREE PAR DILUTION A L'EAU D'UNE SOLUTION SALINE CONCENTREE; B.LA FILTRATION DE LADITE SOLUTION TITREE; C.LE CHAUFFAGE ET LE REFROIDISSEMENT ULTERIEUR DE LA SOLUTION TITREE; D.L'INTRODUCTION DANS LA SOLUTION TITREE DE CORPS FACILEMENT DECOMPOSABLES PAR LA CHALEUR ETOU DEGRADABLES AVEC LE TEMPS, PRECEDEMMENT RENDUS STERILES ET APYROGENES. APPLICATION EN PARTICULIER A LA DIALYSE PERITONEALE.

Automatic peritoneal dialysis bag drainage control during treatment - using modules, each having corresponding clamp and hook arrangement, and UV sterilisation system

APPARATUS Of HEMOFILTRATION ALLOWING TO CONTROL, Independently, CONCENTRATION Of AT LEAST TWO IONIC SUBSTANCES IN the INTERIOR MEDIUM Of a PATIENT

Un appareil d'hémofiltration comporte : - des moyens (20, 24, 34, 38) pour préparer une première solution injectable à partir d'au moins une solution concentrée; - des moyens (33) pour injecter, à un débit d'injection Qpre, la première solution dans la canalisation (5) de prélèvement de sang d'un circuit de circulation extracorporelle de sang (2, 5, 7, 8); - des moyens (50, 51, 52, 53) pour perfuser à un patient une deuxième solution contenant au moins une substance ionique A ayant une concentration déterminée [A] post différente de la concentration [A]pre de cette substance A dans la première solution; - des moyens (60) pour déterminer un débit de perfusion Qpost de la deuxième solution pour que la concentration de la substance A dans le milieu intérieur du patient tende vers une concentration souhaitée [A]des, en fonction de la concentration [A]post post de la substance A dans la deuxième solution, de la concentration souhaitée [A]des, du débit d'injection Qpre de la première solution ...

BLOOD TREATMENT SYSTEMS AND METHODS

Heater-scale for heating fluids for injection into a patient

A heater-scale having a curved supporting member upon which a bag of fluid to be heated can be placed, has a distributed two-dimensional heating element affixed to a lower surface thereof. The curved member is supported by a load cell for generating an electrical signal proportional to the weight of the bag on the heater member, a thermistor is in contact with the fluid whose temperature is to be maintained, a thermistor is affixed to the heater member, and a control system senses the weight and temperature of the bag of fluid as well as the temperature of the heater member for the purpose of nonlinearly adjusting the electrical current supplied to the heater element as fluid is removed from or variable temperature fluid is added to the bag so as to maintain the bag at a predetermined temperature.

Batch filtration system for preparation of sterile fluid for renal replacement therapy

A method and device for blood treatments that use fluids such as dialysate and replacement fluid for renal replacement therapy. In an embodiment, fluid is passed either by pump or passively by gravity feed, through a microporous sterilization filter from a fluid source to a replacement fluid container. The latter forms a batch that may be used during treatment. The advantage of forming the batch before treatment is that the rate of filtering needn't match the rate of consumption during treatment. As a result, the sterilization filter can have a small capacity. In another embodiment, a filter is placed immediately prior to the point at which the sterile fluid is consumed by the treatment process. The latter may be used in combination with the former embodiment as a last-chance guarantee of sterility and/or that the fluid is free of air bubbles. It may also be used as the primary means of sterile-filtration.

Peritoneal dialysis machine touch screen user interface

A peritoneal dialysis machine including a membrane pump and a touch screen display that includes a mode-indicating portion and an operation-descriptive portion, the mode-indicating portion having a plurality of touch sensitive indicia each indicating one of a plurality of modes in which the machine can operate, the display being used to keep a patient continually informed of which one mode of at least three operating modes the machine is operating in, as the operation-descriptive portion changes to display details of a specific operation being carried out within the one mode, the indicia for each of the three operating modes always being visible to the patient while the machine is operating, the operating mode being selected by the patient touching one of the indicia on the screen.

A WATER PURIFICATION APPARATUS AND METHODS FOR CLEANING THE WATER PURIFICATION APPARATUS

A water purification apparatus (300) capable of being cleaned at a point of care, and methods for cleaning the water purification apparatus (300) at the point of care. The water purification apparatus (300) and the methods provide an efficient use of a heater (302) for heat disinfection the water purification apparatus (300), e.g. by recirculating heated fluid to further heat the fluid. Several different cleaning programs are provided that may be utilized for cleaning different parts of the water purification apparatus (300).

DIALYSIS SYSTEM INCLUDING CASSETTE WITH PUMPING TUBES

A hemodialysis system includes a blood treatment machine, a blood pump housed by the blood treatment machine, a first dialysate pump housed by the blood treatment machine, a second dialysate pump housed by the blood treatment machine; and a fluid cassette including an upper portion and a lower portion. The fluid cassette further includes a blood pumping tube extending from the upper portion to the lower portion of the fluid cassette, a first dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette, and a second dialysate pumping tube extending from the upper portion to the lower portion of the fluid cassette.

Dialysis system with enhanced features

A dialysis system includes a dialysis fluid cassette-based membrane blood pump; a dialyzer in fluid communication with the blood pump: first and second dialysis fluid cassette-based balance chambers each having (i) a fresh dialysis fluid compartment in fluid communication with the dialyzer and (ii) a spent dialysis fluid compartment; a dialysis fluid cassette-based fresh dialysis fluid membrane pump in fluid communication with the fresh dialysis fluid compartments of the first and second balance chambers; a dialysis fluid cassette-based spent dialysis fluid membrane pump in fluid communication with the dialyzer and the spent dialysis fluid compartments of the first and second balance chambers; and arterial and venous lines in fluid communication with the dialyzer for patient connection, the arterial and venous lines each including a contact used for electrically detecting a patient access disconnection.

Filtration System for Preparation of Fluids for Medical Applications

A fluid preparation system has a sealed sterilized fluid circuit with a sealed sterilized container with a conductivity sensor in communication with an interior of said container. Further, at least one sealed connector is adapted for adding fluid to said container, and at least one sealed connector is adapted for removing fluid from said container. The conductivity sensor is contained in a test line in communication with said interior and is adapted to be connected to a source of suction thereby to draw a sample of contents of said container. Furthermore, the test line may have a check valve to prevent ingress of contaminants into said container, and the sealed connector is adapted for adding fluid to said container and may have an inline sterile filter. Furthermore, the system may have a controller that controls pumping actuators.

Rotary valves for dialysis systems

In one aspect, a dialysis fluid cassette includes an inlet fluid line, multiple outlet fluid lines, and a valve including an actuation feature by which the valve can be rotated to fluidly communicate the inlet fluid line with a selected fluid line of the multiple outlet fluid lines.

Medical system for performing a fluidic treatment

The invention relates to a medical system for the delivery and/or the extraction of fluid to and/or from a patient. The medical device comprises one user interface unit (1), one mechatronic interface unit (2) including pumping means and at least one patient line (7) with one end connected to said mechatronic interface unit (2) and the other end adapted to be connected to a patient; said medical device being characterized by the fact that said user interface unit (1) is forming a separate unit, distinct from the remaining elements of said medical device, said user interface unit (1) being adapted to be used in a remote location with respect to said mechatronic interface unit (2), said user interface unit (1) and said mechatronic interface unit communicating each others with a cable or a wireless connection. The system according to the invention may advantageously be used in fluid therapies such as Peritoneal Dialysis (PD), such CAPD, APD, CFPD and combinations and Haemodialysis (HD), such ...

PORTABLE REGENERATIVE DIALYSER

ДИАФРАГМЫ КОЛЛЕКТОРА

Verfahren zur Einstellung eines kontinuierlichen Dialysatvolumenstromes in einer Dialysemaschine und Dialysemaschine

Die vorliegende Erfindung betrifft ein Verfahren zur Einstellung eines kontinuierlichen Dialysatvolumenstroms in einer Dialysemaschine mit mindestens zwei diskontinuierlichen Pumpen und einer Steuerung zur Erzeugung eines Soll-Volumenstromes des Dialysats. Erfindungsgemäß wird zur Erzeugung eines möglichst kontinuierlichen Dilaysatvolumenstroms hoher Konstanz die Energie zum Antrieb der Pumpen mit einem entsprechend dem Pump-Zeit-Volumen der jeweiligen Pumpe und dem geforderten Volumen bestimmten Wert konstant eingestellt. Die Erfindung betrifft auch eine Dialysemaschine zur Durchführung des vorgenannten Verfahrens.

Dialysis system, includes heater at the fusion section to heat the fluid to be pumped into the coil, and temperature sensor to detect the temperature within the latter stage of the coil

A fusion section (2), consisting of forward and return pipes (3,4), is formed between a reverse osmosis setting (1) and a coil (12). The return pipe (4) is linked to the coil such that fluid stream can be pumped into the coil by a pump (7). A heater (8) at the fusion section heats the fluid, while a temperature sensor (10) detects the temperature within the latter stage of the coil.

DURCHFLUSSGERAET MIT HEIZVORRICHTUNG

Liquid preparation for use in dialysis

A dialysis machine 120 comprises a reservoir 130 having both liquid and gas inlets 131, 141 and outlets 133, 143, and wherein the reservoir 130 is provided as a part of both liquid and gas circuits. The gas circuit further comprises an air pump 160 and an air heater 134 and is arranged such that, in use, gas flowing in the gas circuit permeates liquid in the reservoir 130 so as to control and regulate the temperature of the liquid. The liquid may thus be used in the preparation of dialysate and/or heat sanitization of the dialysis machine 120. A semi permeable membrane, preferably a mesh 144, may also be arranged in the reservoir 130 such that as air rises up through the water held in the heating and de-aeration chamber 130 micro bubbles are formed at the mesh 144; the micro bubbles serving simultaneously to heat the water and draw out of solution other gasses dissolved in the water. A float valve 146 may also be provided in the reservoir 130.

Modular home dialysis system

A method is described for priming a dialyzer placed in an extracorporeal circuit of a nemodialysis machine in situ. The method comprises the steps of substantially filling the extracorporeal circuit and the blood side of the dialyzer with fluid (such as dialysate, RO water, saline, etc.), and inducing pressure pulses in the fluid. The pressure pulses cause air bubbles from the blood side of the dialyzer to be sheared off the dialyzer membrane. The air bubbles are then conducted from the dialyzer and removed from the extracorporeal circuit. Backfiltering of fluid across the dialyzer from the dialysate circuit into the extracorporeal circuit is performed in synchrony with the pressure pulses to assist in the shearing off of air bubbles from the blood side of the dialyser membrane.

DIALYSIS SYSTEM

... 1388170 Dialysis system MILTON ROY CO 20 Nov 1972 [6 Dec 1971] 53535/72 Heading B1X A dialysis fluid supply system for a dialyzer 24 having a membrane, blood ports for passage of blood through the dialyzer on one side of the membrane, and dialysis ports for passage of dialysis fluid through the dialyzer on the other side of the membrane, comprises a source of dialysis fluid, a head vessel 17, the source of dialysis fluid being connected to continuously supply dialysis fluid to the head vessel, the head vessel having a supply outlet 23 connected to one of the dialysis ports, a standpipe 25 within the head vessel, the standpipe having an open end below the top of the head vessel, the standpipe having an overflow outlet 32 through which dialysis fluid flows when the fluid in the head vessel rises above the open end of the standpipe and flows into the standpipe, a monitor 28 for monitoring at least one of the critical parameters of the dialysis fluid e.g. its conductivity, the monitor being ...

FRAME-MOUNTED FLEXIBLE CONTAINER

PERITONEAL DIALYSIS APPARATUS

... 1326236 Apparatus for supplying dialysis liquid HAUNI-WERKE KORBER & CO KG 10 Dec 1970 [23 Dec 1969] 58741/70 Heading BIX [Also in Division A5] Apparatus for supplying a measured volume of dialysis liquid to a patient for peritoneal dialysis comprises a flexible bag 9 for the dialysis liquid, the bag being contained in a vessel 18 of measuring liquid 17 whose level can be monitored to determine the amount of dialysis liquid in the bag, the apparatus also including a heating device for the liquids, and a device for conveying the dialysis liquid to and from the bag. As shown, the apparatus comprises a supply of dialysis liquid 5 in containers 6, 7, a measuring vessel 18 containing a measuring liquid 17, a heating vessel 27 having a heating coil 32, 34, 33 in the measuring liquid, containers 91, 101 for receiving used dialysis liquid and a control 16 whereby the dialysis may be carried out automatically. The apparatus is used to meter dialysis liquid into the peritoneal cavity of a patient ...

DEVICE TO PERITONALDIALYSE WITH A TO LUFTABSCHEIDUNG AUSGER�STETEN FL�SSIGKEITSVERTEILUND PUMP CARTRIDGE.

PROCEDURE AND DEVICE FOR PERITONEALDIALYSEZIRKULATOREN

EQUIPMENT TO PERITONEALDIALYSE

PROCEDURE FOR INITIALIZING DIALYSIS EQUIPMENT

PERITONEALDIALYSEMASCHINE WITH TENSION-SWITCHABLE HEATING CIRCLE AND OPERATING PROCEDURE FOR IT

Procedure and device for the dialysis of bacteriagrowth-promoting liquids

SYSTEM FOR INFUSING A MULTIPLICITY OF SOLUTIONS INTO THE ABDOMINAL CAVITY OF A PATIENT

BLOOD TREATMENT SYSTEMS AND METHODS

A dialysis system, comprising: a chamber including a membrane that is movable in the chamber and that fluidly separates a first portion of the chamber from a second portion of the chamber, the chamber including a first inlet to the first portion and a second inlet to the second portion; and a blood leak sensor associated with the chamber and arranged to detect blood in the first portion of the chamber, wherein the blood leak sensor is arranged to measure a first level in the first portion and a second level in the second portion for comparison of the first and second levels to each other to determine whether blood is present in the first portion.

DIALYSIS SYSTEM

PRIMING SENSOR FOR A MEDICAL FLUID DELIVERY SYSTEM

A priming sensor for a medical fluid delivery device is disclosed. In an example, the priming sensor includes light emitters and a detector. The detector is configured to detect light emitted by the emitters that interacts with a patient tube connected to the priming sensor. A processor of a medical fluid delivery device causes the emitters to operate in a sweep pattern during a sweep period. The processor receives output data from the detector that is indicative of light detected during the sweep period. The processor creates an output waveform corresponding to the sweep period based on the output data and compares the output waveform to at least one reference waveform to determine one of (a) a no-tube state, (b) a dry tube state, or (c) a wet tube state. The processor provides an output indicative of the comparison for operation of the medical fluid delivery device.

DIALYSIS PROCESS AND APPARATUS FOR ISOLATION OF THERAPEUTICALLY ACTIVE SUBSTANCES

PERITONEAL DIALYSIS SYSTEM WITH SENSORS AND CONFIGURED TO DIAGNOSE PERITONITIS

Peritoneal dialysis, such as automated peritoneal dialysis ("APD") is provided with any one or more or all of the following sensing or feedback features: impedance sensing to detect peritonitis, temperature sensing to detect peritonitis, bio-MEMS sensing to detect peritonitis, and glucose control for diabetes patients, wherein each sensing or feedback feature analyzes patient effluent fluid or fluid dwelling within a patient's peritoneal cavity.

SPLIT RESERVOIR BAGS AND METHOD OF USING SPLIT RESERVOIR BAGS TO IMPROVE THE HEATING AND GENERATION OF DIALYSATE

The present specification provides a reservoir bag for containing a dialysate during a dialysis treatment. The bag has four walls and a membrane extending from a first wall to a second opposing wall which divides the bag into a first and a second sub-reservoir having changeable volumes. The maximum volume of each sub-reservoir is between 80 to 100% of the entire volume of the bag. The bag further includes at least an inlet and an outlet positioned in at least one of the walls for enabling fluid entry into and exit out of the first sub-reservoir and at least an inlet and an outlet positioned in at least one of the walls for enabling fluid entry into and exit out of the second sub -reservoir.

SYSTEMS AND METHODS FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION INCLUDING MIXING AND HEATING THEREFORE

A peritoneal dialysis system includes a cycler including a pump actuator, a heater and a heating pan operable with the heater, and a disposable set operable with the cycler. The heating pan includes a sidewall forming a slot. The disposable set includes a pumping cassette and a heater/mixing container. The pumping cassette includes a pump chamber configured to be actuated by the pump actuator. Additionally, the heater/mixing container is in fluid communication with the pumping cassette and is sized to be received at the heating pan. The heater/mixing container includes a port configured such that when the port is slid into the slot of the heater pan sidewall, the port is prevented from rotating about an axis transverse to a direction of flow through the port.

POWER MANAGEMENT SYSTEM AND METHOD FOR MAXIMIZING HEAT DELIVERED TO DIALYSATE IN A DIALYSIS MACHINE

The amount of electrical power delivered to a dialysate heater in the dialysis machine is maximized without substantially exceeding a predetermined maximum allowed power comsumption for the dialysis machine. The instantaneous power consumed by the machine is measured (132) and compared to the maximum allowed power consumption (134, 136, and 138). The excess of power beyond the instantaneous power consumed up to the maximum allowed power consumption is then made available to the heater (142). The worst case power consumption limitations of the dialysis machine components do not adversely affect the heat available from the heater. The rate at which dialysis treatments may progress may increase or the time required for dialysis treatments may decrease.

PERITONEAL DIALYSIS SYSTEM WITH VARIABLE PRESSURE DRIVE

A variable pressure drive peritoneal dialysis system (10) has a pneumatic pressure system (16) for purging and controlling a flow of dialysate through a disposable dialysate cassette (23) of a disposable dialysate delivery set (21). The pneumatic pressure system (16) has a variable-opening flow proportional valve for supplying air at selected profiled pressure or vacuum to a pneumatic interface (18). The disposable dialysate cassette (23) has a diaphragm pump (P1, P2) actuable by the profiled air pressure or vacuum to move dialysate to and from a patient (28) via the disposable dialysate delivery set (21) at a desired profiled dialysate pressure.

INFUSION ADAPTER FOR CHANGING PRESSURE INSIDE INFUSION LINE IN THE COURSE OF TREATMENT

For heating the dialysate heater member, dialysate hose sets, one set, medical device and method

APPARATUS TRAVERSED BY a FLUID, IN PARTICULAR APPARATUS Of MAKING OF DIALYSATE PROVIDED With a CONTROL DEVICE OF the HEATING Of a LIQUID CROSSING a ROOM, AND ITS PROCESS Of USE

Apparatus through which a fluid passes, in particular apparatus for developing a dialysate, fitted with a system for controlling the heating of a liquid travelling through a chamber

Un appareil d'élaboration de dialysat comprend une chambre (28) parcourue par un liquide; un radiateur électrique (30) logé dans cette chambre; un premier détecteur de température (19), qui détecte la température du liquide avant sa pénétration dans la chambre (28) et délivre des signaux de température d'entrée; et une unité de commande (26), recevant lesdits signaux et commandant un cycle opératoire dudit radiateur (30) en réaction à ces signaux.

투석기

... 본 발명은 유체 시스템의 결합, 특히 카세트의 결합을 위한 결합면과, 결합면 상에 배치되어 유체 시스템의 액츄에이터 영역을 이동시키기 위한 액츄에이터를 갖는 투석기로서, 상기 액츄에이터가 결합면 상에 배치되는 투석기에 관한 것이다. 본 발명에 따르면, 액츄에이터를 가열하기 위한 가열소자가 설치되어 있어, 그 액츄에이터를 통하여 유체 시스템의 액츄에이터 영역 내의 액체를 가열할 수 있다.

DIALYSIS MACHINE

개선된 리저보어 가열 시스템을 갖춘 휴대용 투석기

... 휴대용 투석기는 분리가능한 콘트롤러 유닛 및 개선된 리저보어 가열 시스템을 갖는 기부 유닛을 포함한다. 콘트롤러 유닛은 내부 면을 갖는 도어, 패널을 갖춘 하우징으로서, 상기 하우징과 패널이 상기 도어의 내부 면을 수용하도록 구성된 오목 영역을 형성하는 하우징, 및 상기 패널에 고정되게 부착되는 매니폴드 리시버를 포함한다. 기부 유닛은 내부 팬 및 외부 팬을 가지며 가열 요소를 유지하는 공간에 의해 분리되는 리저보어를 갖는다. 가열 수단은 외부 팬의 외부 표면에 부착되는 전기 접점들과 전기적으로 커플링된다.

Metod vid manövrering av dialysanordning

HOSE ADAPTER FOR INFLUENCING THE PRESSURE INSIDE A HOSE SECTION DURING A MEDICAL TREATMENT

The present invention relates to a hose adapter (100) for connection to at least one hose section (200) of a medical device. The invention further relates to a dialysate hose system having such a hose adapter, to a medical device having such a dialysate hose system, to a method for using the hose adapter according to the invention and to a method for preventing the occurrence of a pressure below a minimum pressure in a dialysate hose system.

APPARATUSES AND PROCESSES FOR WHOLE-BODY HYPERTHERMIA

Apparatuses for use in whole-body hypothermia include a high-flow hyperthermia circuit coupled to a low-flow dialysis circuit in a manner which reduces tensioning of membranes in the dialyzer (152) of the dialysis circuit. The arrangement thereby allows proper membrane movement to assist in mixing a sorbent suspension (176) circulated on the sorbent side of the dialyzer. Additional dialysis apparatuses include advantageous disposable packs (300) including the dialyzer (152), sorbent heat exchangers (186) arranged to cooperate with heating elements on base units of the apparatuses, and adaptations for very high flow rates useful in the hyperthermic treatment of cancers.

HEAT EXCHANGE CIRCUIT

The present invention relates to a heat exchange circuit (30) suitable for promoting heat exchange to/from a physiological fluid. The circuit (30) comprises at least two walls (32 and 34) which rest on each other and are sealed so as to form a duct (36) able to contain a flow of physiological fluid. Each one of the at least two walls comprises, during use, a pattern of corrugations (320 and 340). The corrugations have, at least along sections, a preferential direction. The pattern of corrugations of one wall is positioned so as to be superimposed at least partially on the pattern of corrugations of the other wall so as to form an angle γ between the respective preferential directions, γ ranging between 70° and 110°. Finally at least one of the walls is designed to transfer heat to/from the flow of liquid. The invention relates moreover to a thermal device suitable for use together with the heat exchange circuit. The thermal device (50) comprises two plates (52 and 54), at least one of which ...

Batch dialysate chemical vessel with machine-readable indicator

A vessel storing a batch of chemicals for delivery into a dialysate preparation tank includes a machine readable indicator, permitting automatic identification of the contents of the vessel prior to operating the vessel and introduction of chemicals into a tank where the dialysate solution is mixed. Various types of machine-readable indicators may be used, such as, for example, "touch" memory buttons, bar codes, or magnetic strips. Suitable reading devices for the machine-readable indicators are provided for reading the contents of the bottle.

Method of rinsing back blood to hemodialysis patient

A method is described herein for automatically rinsing blood back to a patient. The method comprises the steps of pumping dialysate (or, alternatively, saline solution) through a dialyzer into an extracorporeal circuit, and pumping blood in the extracorporeal circuit out the arterial and venous lines back to the patient. Optical sensors monitor the concentration of blood in the arterial and venous lines as the blood is being pumped from the extracorporeal circuit back to the patient. The return flow of blood is ceased when the concentration of blood in the arterial and venous lines drops to a predetermined threshold level, thereby preventing excess fluids from being returned to the patient.

BLOOD TREATMENT SYSTEMS AND METHODS

The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. According to one aspect, a blood pump is configured to pump blood to a dialyzer of a hemodialysis apparatus, the blood pump comprising a pneumatically actuated or controlled reciprocating diaphragm pump. In an embodiment, the diaphragm of the pump comprises a flexible membrane formed or molded to generally conform to a curved inner wall of a pumping chamber or control chamber of the pump, wherein the diaphragm is pre-formed or molded to have a control side taking a convex shape, so that any elastic tension on the diaphragm is minimized when fully extended into a control chamber of the pump. In another aspect, a system for monitoring the adequacy of blood flow in a blood line of the hemodialysis apparatus ...

Peritoneal Dialysis Systems, Devices, and Methods

A method of performing a dialysis treatment includes using a pump and a dialysate supply line to transport peritoneal dialysis fluid, the supply line having a proximal end into which peritoneal dialysis fluid is supplied and from which spend dialysate is withdrawn, and a distal end which is connected to a patient's peritoneal access. The method further includes generating proximal and distal pressure signals using pressure detectors located at both the proximal and distal ends, respectively, of said supply line. During a drain cycle in which spent dialysate is pumped from the patient, the method includes, responsively to the proximal and distal pressure signals, detecting a characteristic of a pressure difference between the distal and proximal ends whose magnitude is determined by a predicted change in dialysate properties, and responsively to the characteristic, generating a signal indicating the change in dialysate properties.

Cassette system integrated apparatus

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

VERFAHREN UND VORRICHTUNG FÜR PERITONEALDIALYSE-ZIRKULATOREN

HAEMODIALYSEVORRICHTUNG

Verfahren und Vorrichtung für die Herstellung von sterilen wässrigen Lösungen.

Modular home dialysis system

Disclosed is an apparatus for establishing fluid connection between an extracorporeal circuit and a source of disinfection fluids, with the extracorporeal circuit comprising a dialyzer, an arterial blood line and a venous blood line; ```a disinfection line for carrying disinfection fluids from the source of disinfection fluids to the extracorporeal circuit; ```a disinfection manifold comprising a first and a second port, the first port for receiving the arterial line, and the second port for receiving the venous line; ```a return line establishing a fluid connection with the disinfection manifold and carrying disinfection fluids from the extracorporeal circuit; ```whereby disinfection fluids passed into the disinfection manifold by the disinfection line are routed through the arterial and venous blood lines and out of the extracorporeal circuit via the return line. Also disclosed is an apparatus for directing disinfection fluids to and from an extracorporeal circuit, the extracorporeal ...

Dialysis liquid regenerator

A portable machine for regenerative dialysis comprises a dialyzing liquid reservoir in which is immersed a suction duct connected to a heating tube the temperature of which is controlled by a thermal probe pair piloting a temperature adjusting element. The outlet of the heating tube is connected to the suction side of a dialyzing liquid pump having a first and second delivery ducts opening in the dialyzing liquid reservoir wherein are interposed a dialyzer element and a dialyzing liquid regenerating cartridge respectively.

Cassette system integrated apparatus

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

Medical Device Heaters and Methods

A medical device having a heater with at least one heating element which has mains voltage applied to it by a heating control unit. The heating control unit includes a monitoring arrangement and a switching arrangement. The monitoring arrangement can recognize the zero crossings of the mains voltage, and the switching arrangement can switch the at least one heating element on or off in the zero crossing. The heating control unit controls the power of the heating by switching on and off of one or more half cycles of the mains AC voltage.

Dialysis cassettes and related systems and methods

A method that includes conveying overheated dialysate through a cassette in a manner to reduce the temperature of the overheated dialysate, and a dialysis system including a control unit configured to cause overheated dialysate to be conveyed through a cassette in a manner to reduce the temperature of the overheated dialysate.

Non-invasive radio frequency liquid level and volume detection system using phase shift

A medical fluid system includes a medical fluid pump; a container holding a fluid to be pumped by the medical fluid pump, the fluid at a first time having a first conductivity, the fluid at a second time having a second conductivity; and a radio frequency level sensor positioned in operable relation with the container, the radio frequency operation of the level sensor configured so as to be (i) indicative of a level of the fluid in the container and (ii) at least substantially independent of whether the fluid has the first conductivity or the second conductivity. The medical fluid system can determine the level of medical fluid by measuring the resistance, impedance or phase shift seen by the sensor.

Multichamber container for preparing medicinal solutions

The subject matter of the present invention is a multichamber container and a method for preparing medical fluids composed of concentrates which make a contribution toward the electrical conductivity of the solution and are additionally prepared from concentrates which do not make a contribution toward the electrical conductivity of the solution. The inventive multichamber container is characterized in that it is constructed by dividing the solution components into multiple chambers, so that following the dissolving due to breaking open of the first chamber border of a solution component, which makes a contribution toward the electrical conductivity of the medicinal solution, another chamber border of another solution component which does not make any contribution toward the electrical conductivity of the solution is broken open.

Filtration system for preparation of fluids for medical applications

Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed either by pump or passively by gravity feed, through various filtration elements from a fluid source to a treatment fluid container. The latter forms a batch that may be used during treatment. The advantage of forming the batch before treatment is that the rate of filtering needn't match the rate of consumption during treatment which provides multiple benefits and liabilities to overcome, as discussed herein. Mechanisms for preparing pure water for infusion or medicaments are described such as elimination of chlorine and colloidal aluminum. Also various control mechanisms to help avoid contamination are describe.

Cassette system integrated apparatus

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes.

Blood treatment systems and methods

Dialysis systems are disclosed comprising new fluid flow circuits. Systems may include blood and dialysate flow paths, where the dialysate flow path includes balancing, mixing, and/or directing circuits. Dialysate preparation may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit fluid flow paths may be isolated from electrical components. A gas supply in fluid communication with the dialysate flow path and/or the dialyzer able to urge dialysate through the dialyzer and urge blood back to the patient may be included for certain emergency situations. Fluid handling devices, such as pumps, valves, and mixers that can be actuated using a control fluid, may be included. Control fluid may be delivered by an external pump or other device, which may be detachable and/or generally rigid, optionally with a diaphragm dividing the device into first and second compartments.

Pumping cassette

A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.

Dialysis machine with electrical insulation for variable voltage input

A dialysis machine includes: a source of dialysis solution; a pump configured to pump the dialysis solution; a heater configured to heat the dialysis solution; an electrical input receiving power from a remote power source; and a housing supporting the pump, the heater and the electrical input, the housing including an electrical insulation rated for 240 VAC such that the remote power source can be either 110 or 240 VAC.

Tubing adapter for influencing the pressure inside a tubing section during a medical treatment

A tubing adapter for interconnection with a least one tubing section of a medical device, a dialysis fluid tubing system including such a tubing adapter, a medical device including such a dialysis fluid tubing system, and a method for avoiding a pressure within a dialysis fluid tubing system that is below a minimum pressure are described.

Producing method for living organism-applicable hydrogen-contained fluid and producing apparatus for the same

A producing method for a living organism-applicable hydrogen-contained fluid, which includes hydrogen molecules in living organism-applicable fluid enclosed in a container ( 2 i ) with hydrogen molecule permeability, is provided. This method includes a hydrogen exposing step of exposing hydrogen molecules to the container ( 2 i ) in which the living organism-applicable fluid is enclosed from the outside of the container without opening the container. The container with hydrogen molecule permeability is one that allows a dissolved hydrogen concentration of a normal saline solution to be 1 ppb or greater when the container filled with the normal saline solution is immersed for 5 hours in a volume of hydrogen water, which stably maintains an approximately saturated state (1.6 ppm at 20 C degrees under 1 barometric pressure) and is 20 times the content volume of the container.

Bag with a flexurally rigid plastic part welded into it

The subject of the invention is a bag for receiving, preparing and producing dialysis fluid. The invention relates in particular to a bag having a sealing bordering line and a flexurally rigid hard plastic part connected to the film material. The hard plastic part is connected to the film material separately from the sealing bordering line and offers an area for gripping the bag for fastening it without having to act mechanically on the sealing bordering line in a direct manner.

Filtration system for preparation of fluids for medical applications

Systems, methods, and devices for preparation of water for various uses including blood treatment are described. In embodiments, fluid is passed through a first filtration step which is effective for creating purified water and a pair of ultrafilters placed at the outlet. The ultrafilters are separated by an intervening flow path to prevent grow-through from the outlet end upstream. In embodiments, a recirculation path with an air removing filter helps to eliminate air from the ultimate product water.

Reusable effluent drain container with key feature for dialysis and other medical fluid therapies

A dialysis system includes a source of effluent dialysis fluid, a drain container configured to receive the effluent dialysis fluid through a drain tube, and a load cell. The drain container includes an at least semi-rigid body defining a first key feature. The load cell includes a second, mating key feature positioned and arranged to mate with the first key feature.

Dialysis machine

Embodiments of the present disclosure include a dialysis system having a disposable cartridge which includes one or more flowpaths arranged on or within the cartridge.

Dialysis implant and methods of use

A device and methods for treating renal failure are disclosed. One embodiment of the device is an implantable peritoneal dialysis device. When in use, the device can have a semi-permeable reservoir implanted in the peritoneal cavity. The reservoir can receive blood waste and drain through one or more conduits, via a pump, to the biological bladder. Solids and/or a solution benefiting dialysis can be pumped to the reservoir and/or implanted in the peritoneal cavity.

Apparatus and method for filling solution bags for dialysis

The present invention relates to an apparatus and to a method for filling a solution bag for dialysis with a liquid, wherein the apparatus comprises a needle for introduction into a filling line or filling opening of the bag, wherein the needle is a double wall needle having a preferably thermally conductive outer wall and having an inner wall, with a thermal insulation being present between the outer wall and the inner wall; and with a heating element being provided that is configured to heat the outer side of the outer wall to a temperature above the temperature of the inner side of the inner wall.

Treatment Fluid Multi-Stream Blood Warmer

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. A blood treatment system treats blood with multiple fluids and performs fluid balancing on a patient's blood compartment. Multiple streams influence the patient temperature but only a subset of the fluids are dynamically temperature regulated. The system regulates a temperature of the flow, for example, of dialysate in order to regulate the return temperature of blood, in such a way that the temperature effect of the multiple streams is compensated.

SORBENT POUCH

A sorbent pouch for use in sorbent dialysis. The sorbent pouch allows for fluid to freely pass into and through the sorbent materials, while keeping the sorbent materials inside the sorbent pouch. 1. A sorbent pouch , comprising:a porous material forming in-part a sorbent containing a material consisting essentially of alumina, the porous material retaining at least 98% by weight of the alumina.2. The sorbent pouch of claim 1 , the porous material allowing dissolved urease to pass through the porous material.3. The sorbent pouch of claim 1 , the porous material preventing undissolved urease from passing through the porous material.4. The sorbent pouch of claim 1 , wherein the porous material is selected from the group consisting of bolting cloth claim 1 , porous polymer claim 1 , porous metal claim 1 , cotton claim 1 , ashless filter paper claim 1 , Dacron claim 1 , and polyethylene terephthalate.5. The sorbent pouch of claim 1 , wherein the sorbent pouch has a shape selected from the group consisting of a circular shape claim 1 , a square shape claim 1 , a triangular shape claim 1 , a rectangular shape claim 1 , and a disc shape.6. The sorbent pouch of claim 1 , wherein the sorbent pouch is shaped to be adapted into an internal cavity defined by a sorbent cartridge in which the sorbent pouch is housed.7. The sorbent pouch of claim 1 , wherein the sorbent pouch has a semi-rigid structure.8. The sorbent pouch of claim 1 , wherein the sorbent pouch has a rigid structure.9. The sorbent pouch of claim 1 , wherein the sorbent pouch has a flexible structure.10. The sorbent pouch of claim 1 , further comprising side portions constructed from a fluid impermeable material.11. The sorbent pouch of claim 10 , further comprising an elastomeric material disposed on a side portion of the sorbent pouch.12. The sorbent pouch of claim 1 , wherein the porous material is impregnated with an antimicrobial substance and/or an anticoagulant.13. The sorbent pouch of claim 1 , wherein the ...

Dry Acid Concentrate in Granulate form

The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container () comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit. 1. Dry concentrate suitable to form a liquid acid concentrate or a part of a liquid acid concentrate usable in dialysis comprisinga first component comprising a first granulate comprising a plurality of first granules comprising sodium chloride and glucose, anda second component comprising a second granulate comprising a plurality of second granules, wherein said granules comprise at least one further physiologically acceptable electrolyte, which is different from sodium chloride,or a second component in the form of a powder, wherein said powder comprises at least one further physiologically acceptable electrolyte which is different from sodium chloride, and wherein said powder comprises a plurality of fine particles, wherein each particle comprises or consists of one of said at least one further physiologically acceptable electrolyte,or a mixture of said second granulate and said powder.2. Dry concentrate according to claim 1 , wherein the first and the second component comprise or consist of said first and second granulate.3. Dry concentrate according to claim 2 , wherein the granules of the first component exhibit a higher average equivalent diameter than the granules of the second component.4. Dry concentrate according to claim 1 , wherein the first granulate comprises at least 50 wt-% claim 1 , e.g. at least 75 wt-% or at least 90 wt-% of granules claim 1 , respectively based on the total weight of the first granulate in the dry concentrate claim 1 , which have an equivalent diameter of above 0.5 to below 12.5 mm.5. Dry ...

PACKAGING OF POWDERY MATERIAL FOR PREPARATION OF A MEDICAL SOLUTION

A package () is configured to store a powdery material () which is to be mixed with a solvent to form a medical solution, such as a dialysis solution. The package () comprises a filled cavity portion () containing the powdery material (), optionally separated into groups of different composition, and a tab portion () integrally formed with the filled cavity portion () and being swept around the filled cavity portion () so as to define a roll-up package. The tab portion () forms a protective barrier that shields the powdery material (), e.g. by counteracting transport of moisture into and out of the package. The tab portion () may also stabilize the package. The roll-up package is compact, and simple to manufacture and handle. 1. A package for storing powdery material which is to be mixed with a solvent to form a medical solution , said package comprising:a filled cavity portion containing the powdery material, anda tab portion integrally formed with the filled cavity portion and being swept around the filled cavity portion so as to define a roll-up package.2. The package of claim 1 , wherein the roll-up package is generally cylindrical.3. The package of claim 1 , wherein the tab portion is swept in at least one full turn around the filled cavity portion.4. The package of claim 1 , which defines a sealed cavity that includes the filled cavity portion and an empty cavity portion that is free of powdery material and is located adjacent to the filled cavity portion claim 1 , and wherein the tab portion includes the empty cavity portion.5. The package of claim 4 , comprising first and second overlapping sheets of flexible material which are joined to define the sealed cavity.6. The package of claim 5 , wherein the sealed cavity extends from a first cavity end to a second cavity end claim 5 , the powdery material being arranged in the sealed cavity such that the filled cavity portion is located at the first cavity end and the empty cavity portion extends from the filled ...

INTEGRATED WATER TESTING SYSTEM AND METHOD FOR ULTRA-LOW TOTAL CHLORINE DETECTION

A dialysis method and system for determining an amount of total chlorine in a partially purified water sample is disclosed. The system includes a water machine that produces at least partially purified water including an at least partially purified water sample and a dialysis machine that provides a dialysis treatment to a patient. The dialysis machine receives the at least partially purified water from the water machine to prepare dialysis fluid for the dialysis treatment. The system also includes a total chlorine detector configured to receive the at least partially purified water sample, at a first time apply a source voltage to the at least partially purified water sample, and at a second time stop applying the source voltage to the at least partially purified water sample and instead monitor a sensed electrical parameter to determine an amount of total chlorine in the at least partially purified water sample. 1. A method of determining an amount of total chlorine in a water sample for a hemodialysis treatment , the method comprising:producing, via a water purification machine, an at least partially purified water sample;receiving, in a total chlorine detector, the at least partially purified water sample from the water purification machine;applying at a first time, via the total chlorine detector, a source voltage to the at least partially purified water sample;removing at a second time, via the total chlorine detector, the source voltage to the at least partially purified water sample;measuring, after the second time, via the total chlorine detector, an electrical parameter of the at least partially purified water sample; anddetermining, via the total chlorine detector, the amount of total chlorine in the at least partially purified water sample based on the measured electrical parameter.2. The method of claim 1 , wherein the total chlorine detector is included within at least one of the water purification machine or a dialysis machine that receives at least ...

FLEXIBLE CONTAINER SYSTEMS AND NOZZLES, AND RELATED METHODS

A container system includes at least one flexible wall defining a compartment containing a dissolvable solid or concentrate, a support adjacent a first end of the at least one flexible wall, and a nozzle assembly coupled to a second end of the at least one flexible wall. The second end of the wall is distal from the first end. The nozzle assembly comprises a hollow body defining a longitudinal axis. The hollow body further defines a plurality of orifices through a wall thereof. Each orifice is able to form a fluid connection between an interior volume within the hollow body and the compartment. Each orifice is configured to deliver liquid from the interior volume to the compartment in a direction having an angle of between 5° and 85° from a direction of the longitudinal axis. Related nozzles and methods are also disclosed. 1. A container system comprising:at least one flexible wall defining a compartment containing a dissolvable solid or concentrate;a support adjacent a first end of the at least one flexible wall; anda nozzle assembly coupled to a second end of the at least one flexible wall, the second end distal from the first end, the nozzle assembly comprising a hollow body defining a longitudinal axis;wherein the hollow body further defines a plurality of orifices through a wall thereof, each orifice able to form a fluid connection between an interior volume within the hollow body and the compartment, and each orifice configured to deliver liquid from the interior volume to the compartment in a direction having an angle of between 5° and 85° from a direction of the longitudinal axis.2. The container system of claim 1 , further comprising a frangible seal configured to limit transfer of material from the compartment through the nozzle assembly until the frangible seal has been breached.3. The container system of claim 2 , wherein the frangible seal comprises an adhesive bonded to the at least one flexible wall within the compartment.4. The container system of ...

Medicament Preparation and Treatment Devices, Methods, and Systems

A medicament preparation system, according to an embodiment, includes a water purification module and a medicament proportioning module. The system is configured to allow convenient and safe use in a home environment or a critical care environment as well as others affording safety, reliability, and a compact form factor. 1. A compact medicament supply system to support blood treatment systems susceptible to leakage current from an electric heater used to heat medicament due to the inherent formation of a fluid path between the electric heater and a patient , comprising:a water purification module having a pump and a controller, the water purification module having deionization filters of sufficient capacity and the pump controlled to purify water to a level of purity exceeding 1 megaohm-cm and providing product water at least that level of purity to a product water output connected to an electric heater;a water channel of a predefined length and of electrically insulating material connecting the electric heater to a medicament proportioning module disposable fluid circuit, the water channel receiving said product water from said electric heater;the electric heater being of a configuration that places the product water in direct contact with permanent non-disposable surfaces of a flow channel in said electric heater; anda sterile filter connected to receive said product water at a point along said water channel, the water channel having a output connector for connecting to the medicament proportioning system;the medicament proportioning system, principally of electrically insulating material, connected to supply a conductive medicament solution to a treatment component connected to a patient via a blood circuit including a patient access such that a continuous fluid path between said electric heater and said patient access at times during a treatment;a controller adapted for controlling the electric heater responsively to a measured temperature and temperature ...

Devices, systems, and methods for heating dialysate for dialysis machines

Dialysis machines and methods for heating dialysate before delivery into a dialysis patient (e.g., peritoneal dialysis machines) may comprise a dialysis machine including one or more internal cooling components configured to expel heated air from the dialysis machine. A receptacle may be configured to receive one or more containers of dialysate. The one or more containers of dialysate may be positionable relative to the expelled heated air of the dialysis machine. The expelled heated air may be flowable around the one or more containers of dialysate to increase a temperature of the dialysate. The receptacle may include a stand for positioning the dialysis machine such that the expelled heated air is directed around the one or more containers of dialysate.

Method and System for Controlled Hyperthermia

An improved system and methods for treatment of cancer and other diseases including complications from late-stage viral infections by inducing hyperthermia in a patient relying on withdrawing blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit. Blood is heated by passing through the extracorporeal circuit at a controlled rate until a target body core temperature in is achieved. Usually, the blood will be subjected to a continuously re-circulating dialysis to balance electrolytes. Additionally, the blood will be subjected to a continuously recirculating regeneration through a carbon sorbent column where toxins and contaminants are removed. The blood temperature is maintained at the target blood temperature for a treatment period, and the blood is cooled after the treatment period has been completed. The method can also be effective in treating rheumatoid arthritis, scleroderma, hepatitis, sepsis, the Epstein-Barr virus, and patients with life threatening complications from other viruses, including the COVID-19 virus. A method for removing viruses from the blood supply in an external circuit is also presented. An adjunct of the present invention is enhanced production of stem cells as a result of employing the HEATT process. A further adjunct is production of transgenic swine with extant viral infections. 1. An improved method for inducing hyperthermia in a patient , said method comprising:a. slowly withdrawing a portion of blood from the patient and returning the withdrawn blood to the patient to establish an extracorporeal flow circuit;b. passing water or another heat exchange medium through a heat exchanger to heat the blood;c. slowly heating blood passing through the extracorporeal circuit at a rate in the range from 0.05° C./min to 0.15° C./min in order to prevent vascular collapse until a target body core temperature in the range from 41.8° C. to 42.2° C. is achieved;d. maintaining the blood ...

Method for extracorporeal carbon dioxide removal

The present invention generally relates to a process suitable for extracorporeal lung support. The process relies on exposing blood, separated by a semipermeable membrane from the dialysis liquid. The dialysis liquid of the present invention comprises a buffering agent and has a high buffering capacity for H* ions. Carbon dioxide, bicarbonate and hydrogen cations can be efficiently transported across a semipermeable membrane to the dialysis liquid. The present invention also allows for the regeneration and recycling of the dialysis liquid, and thus for its recycling and repeated use. The versatility of the dialysis liquid allows to adjust the pH of the dialysis liquid, add fluids to the dialysis liquid and/or to the blood in the extracorporeal circuit and to remove substances from the blood in the extracorporeal circuit, depending on the conditions and needs. Thus, the present invention is versatile, and suitable for treating or preventing respiratory acidosis, metabolic acidosis, diseases associated with lung malfunction and/or kidney malfunction and/or liver malfunction. For example, when the kidney function is limited, the acid-base balance of the blood can be provided by the method of the present invention; and when the liver function is limited, toxins can be removed from blood by the method of the present invention.

SYSTEM AND METHOD FOR PREPARATION OF A MEDICAL FLUID

Systems and apparatuses for preparing a medical fluid are disclosed. In an example embodiment, a system is configured to initially control a dosing of a first concentrate, while not feeding a second concentrate, under feedback control via a concentration sensor to a first pump to feed the first concentrate. When a concentration has reached a preselected concentration level, a value for a feeding parameter for the first pump to feed the first concentrate is determined. Additionally, the system is configured to control the dosing of both the first and the second concentrates by switching the feedback control via the concentration sensor, from control of the first pump to control of a second pump to feed the second concentrate. During this time, the system controls the first pump to feed the first concentrate based on the determined value of the feeding parameter. 1: A system for dosing of at least two concentrates into water for on-line preparation of a medical fluid , said system comprising:a main line for feeding of water;a first line with a first pump for feeding of a first concentrate into the main line at a first mixing point;a second line with a second pump for feeding of a second concentrate into the main line at a second mixing point;a concentration sensor arranged in the main line downstream of both the first and the second mixing points; and (i) initially control the dosing of the first concentrate, while not feeding the second concentrate, under feedback control via the concentration sensor to the first pump to feed the first concentrate, such that when a concentration measured by the concentration sensor has reached a first preselected concentration level, a value for a feeding parameter for the first pump to feed the first concentrate is determined, and', '(ii) after the determination of the value for the feeding parameter, control the dosing of both the first and the second concentrates by switching the feedback control via the concentration sensor, from ...

MAGAZINE HAVING SOLUTION BAGS FOR DIALYSIS AND METHOD FOR FILLING SAME

The present invention relates to a magazine having a plurality of solution bags for dialysis received therein, wherein the plurality of solution bags are identical; wherein the plurality of solution bags are fixed in a stationary manner in an identical orientation at different, but identically designed holding positions of the magazine; and wherein the holding positions are configured such that the solution bags can be removed from the magazine. The invention furthermore relates to a method of filling the solution bags. 1. A magazine having a plurality of solution bags for dialysis received therein , wherein the plurality of solution bags are identical; wherein the plurality of solution bags are fixed in a stationary manner in an identical orientation at different , but identically designed holding positions of the magazine; and wherein the holding positions are configured such that the solution bags can be removed from the magazine.2. A magazine in accordance with claim 1 , characterized in that the solution bags are bags composed of connected and advantageously welded plastic films.3. A magazine in accordance with claim 1 , characterized in that the solution bags have a material projection which is not in direct contact with the internal volume and in which at least one hole or a zone of weakened material is preferably worked claim 1 , with the material projection preferably being a peripheral weld seam.4. A magazine in accordance with claim 1 , characterized in that the magazine has a plurality of identical carriers in which a respective one solution bag is fixed claim 1 , with the carriers being stacked directly at one another.5. A magazine in accordance with claim 4 , characterized in that the carriers have an areal base element and a framework extending in the normal direction claim 4 , wherein the solution bag lies on the base element and is surrounded by the framework.6. A magazine in accordance with claim 5 , characterized in that the carriers have at least ...

HOLLOW FIBER MEMBRANE-TYPE ARTIFICIAL LUNG

The present invention provides a hollow fiber membrane oxygenator comprising 1. A hollow fiber membrane oxygenator comprisinga housing comprising a blood flow path;a blood inlet port and a blood outlet port disposed in the housing so as to allow blood to flow through the blood flow path,a gas exchange part comprising a bundle of a plurality of hollow fiber membranes disposed in the blood flow path;a gas inflow port and a gas outflow port provided in the housing so as to allow an oxygen-containing gas to flow through lumens of the hollow fiber membranes;a gas temperature control part for adjusting the temperature of the gas flowing through the lumens of the hollow fiber membranes; andthe gas temperature control part comprises cold- or warm-water flow pipes which is inserted in the hollow fiber membranes.2. The hollow fiber membrane oxygenator according to claim 1 , wherein the oxygen-containing gas further contains helium gas.3. (canceled)4. The hollow fiber membrane oxygenator according to claim 2 , wherein the gas temperature control part comprises rod-shaped members disposed in hollow fibers claim 2 , and cooling mechanisms for cooling the rod-shaped members.5. The hollow fiber membrane oxygenator according to claim 4 , wherein the hollow fiber membranes and the gas temperature control part constitute a heat exchange part claim 4 , and the oxygenator is a hollow fiber membrane-based gas and heat exchanger.6. The hollow fiber membrane oxygenator according to claim 2 , further comprising a gas separation membrane for recovering helium from gas released from the gas outflow port.7. The hollow fiber membrane oxygenator according to claim 1 , wherein the gas temperature control part selectively cools the local area inside the oxygenator where the blood and hollow fiber membranes come into contact with each other.8. The hollow fiber membrane oxygenator according to claim 1 , wherein the gas temperature control part adjusts the temperature of the oxygen-containing gas in ...

SYSTEMS AND METHODS FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION INCLUDING MIXING AND HEATING THEREFORE

A peritoneal dialysis system includes a cycler including a pump actuator, a heater and a heating pan operable with the heater, and a disposable set operable with the cycler. The heating pan includes a sidewall forming a slot. The disposable set includes a pumping cassette and a heater/mixing container. The pumping cassette includes a pump chamber configured to be actuated by the pump actuator. Additionally, the heater/mixing container is in fluid communication with the pumping cassette and is sized to be received at the heating pan. The heater/mixing container includes a port configured such that when the port is slid into the slot of the heater pan sidewall, the port is prevented from rotating about an axis transverse to a direction of flow through the port. 1. A peritoneal dialysis system comprising:a cycler including a control unit and a pump actuator under control of the control unit; and a pumping cassette having a pump chamber configured to be actuated by the pump actuator, and', 'a mixing container in fluid communication with the pumping cassette,, 'a disposable set operable with the cycler, the disposable set including'}wherein the control unit is programmed to promote mixing of at least two fluids by (i) causing the pump actuator to operate the pump chamber to pull the at least two fluids from the mixing container into the pump chamber, (ii) thereafter causing the pump actuator to operate the pump chamber to push the at least two fluids from the pump chamber to the mixing container, and (iii) repeating (i) and (ii) at least one time.2. The peritoneal dialysis system of claim 1 , wherein the control unit is configured such that after (i) claim 1 , (ii) and (iii) are performed claim 1 , a sample of the mixed at least two fluids is caused to undergo a test using a sensor claim 1 , and wherein at least one of prior to or after the test the sensor is bypassed or used for a different purpose.3. The peritoneal dialysis system of claim 1 , wherein after (i) claim 1 ...

DIALYSIS SYSTEM HAVING INDUCTIVE HEATING

A dialysis fluid system includes a dialysis fluid inlet; a dialysis fluid outlet; a pump positioned and arranged to pump dialysis fluid through the dialysis fluid inlet and the dialysis fluid outlet; and an inductive heater located between the dialysis fluid inlet and the dialysis fluid outlet, the inductive heater including a fluid flowpath positioned and arranged to receive non-heated dialysis fluid from the dialysis fluid inlet and to output heated dialysis fluid to the a dialysis fluid outlet, a conductive heater element located within the fluid flowpath so as to be or act as a secondary coil of a transformer, and a primary coil of the transformer located outside of the fluid flowpath and positioned so as to magnetically induce a current into the conductive heater element, causing the conductive heater element and surrounding fluid to heat. 1. A dialysis fluid system comprising:a dialysis fluid inlet;a dialysis fluid outlet;a pump positioned and arranged to pump dialysis fluid through the dialysis fluid inlet and the dialysis fluid outlet; and a fluid flowpath positioned and arranged to receive non-heated dialysis fluid from the dialysis fluid inlet and to output heated dialysis fluid to the dialysis fluid outlet,', 'a conductive heater element located within the fluid flowpath so as to be or act as a secondary coil of a transformer, and', 'a primary coil of the transformer located outside of the fluid flowpath and positioned so as to magnetically induce a current into the conductive heater element, causing the conductive heater element and surrounding dialysis fluid to heat., 'an inductive heater located between the dialysis fluid inlet and the dialysis fluid outlet, the inductive heater including'}2. The dialysis fluid system of claim 1 , wherein the fluid flowpath and the conductive heater element are located within a heater housing in fluid communication with the dialysis fluid inlet and the dialysis fluid outlet.3. The dialysis fluid system of claim 2 , ...

Modular Reservoir Assembly for a Hemodialysis and Hemofiltration System

The present specification discloses a dialysis system having a reservoir module with a reservoir housing defining an internal space, a surface located within the internal space for supporting a container that contains dialysate, and a conductivity sensor located within the internal space, where the conductivity sensor has a coil, a capacitor in electrical communication with the coil, and an energy source in electrical communication with the circuit.

EXTRACORPOREAL BLOOD TREATMENT SYSTEM WITH HEAT RECOVERY

Blood treatment/dialysis systems are disclosed. The systems include a water treatment unit, preferably of the reverse osmosis type, whose outlet has connected thereto a water supply line provided with a number of branch connections having fluidly coupled thereto blood treatment/dialysis machines in a selective manner, and a drain line through which exhausted blood treatment fluid can be discharged from fluidly coupled blood treatment/dialysis machines. Also disclosed is a machine-external heat exchanger, which is connected to the water supply line upstream of the branch connections on one side and to the drain line on the other side. 113-. (canceled)14. An extracorporeal blood treatment system comprising: 'a water treatment unit having an outlet connected to at least one water supply line that opens into at least one line section provided with a number of branch connections and at least one drain line through which exhausted blood treatment/dialysis fluid can be discharged; and', 'a stationary system area including 'a number of blood treatment machines fluidly coupled to the branch connections and the at least one drain line in a selective manner; and', 'a non-stationary system area including{'b': 1', '1', '1', '1', '2, 'a stationary heating unit disposed externally to the blood treatment machine and comprising a first heat exchanger (WT) having one side (WT/) connected to the at least one water supply line between the water treatment unit and the line section including the branch connections, and having the other side (WT/) connected to the at least one drain line.'}15. The extracorporeal blood treatment system according to claim 14 , further comprising:{'b': '1', 'a central electronic control unit (CT) electrically connected to the blood treatment machines so as to obtain information on at least prevailing operating phases of these machines and which, in accordance with this information, controls a stationary heating unit that is connected to the at least one ...

DIALYSIS SYSTEM COMPRISING HEAT RECOVERY

Dialysis systems including a water treatment unit preferably of the osmosis type, a drain line, and a heat exchanger are disclosed. A water supply line is connected to an outlet of the water treatment unit. The water supply line includes branch connections to which dialyzers are selectively fluid-coupled. Used-up dialysis fluid can be discharged from fluid-coupled dialyzers through the drain line. The heat exchanger, which is external to the dialyzers, connected on one side to the water supply line directly upstream of the branch connections and on the other side to the drain line. 18-. (canceled)9. A dialysis system comprising:a water treatment unit having an outlet connected to a water supply line that opens into at least one line section provided with branch connections to which dialyzers are fluidly coupled in a selective manner;a drain line through which the used dialysis fluid can be discharged from the fluid-coupled dialyzers; and{'b': 1', '1', '1', '1', '2, 'a first heat exchanger (WT) external to the dialyzer having one side (WT/) connected to the water supply line between the water treatment unit and the line section including the branch connections and another side (WT/) connected to the drain line.'}10. The dialysis system according to claim 9 , wherein the water supply line defines a ring line claim 9 , which claim 9 , downstream of the at least one line section including the branch connections claim 9 , is returned to the water treatment unit claim 9 , said ring line being there configured as a feedback line.11. The dialysis system according to claim 10 , further comprising a temperature transfer unit including:{'b': 2', '2', '1', '1', '2', '2, 'a second heat exchanger (WT) disposed externally to the dialyzer having one side (WT/) connected to the water supply line between the water treatment unit and the first heat exchanger (WT), and another side (WT/) connected to the feedback line between the water treatment unit and the line section including the ...

CONTAINER

The present invention relates to a combination of a container comprising a connecting portion and of a fluid preparation device, in particular a dialysis machine, which fluid preparation device is suitable for mounting and connecting the connecting portion of the container, wherein the fluid preparation device comprises at least one line which is in fluid communication with the interior of the container at least in the connected position of the container, the container being filled with a first medium, wherein the combination and preferably container comprises a reservoir containing a second medium, wherein the fluid preparation device comprises means for opening the reservoir so that the first and second medium are mixed with each other. 130505032305052303030301005056100. A combination of a container () comprising a connecting portion and of a fluid preparation device () , in particular a dialysis machine , which fluid preparation device () is suitable for mounting and connecting the connecting portion () of the container () , wherein the fluid preparation device () comprises at least one line () which is in fluid communication with the interior of the container () at least in the connected position of the container () , the container () being filled with a first medium , characterized in that the combination and preferably container () comprises a reservoir () containing a second medium , wherein the fluid preparation device () comprises means for opening () the reservoir () so that the first and second medium are mixed with each other.2525230525130525251525152. A combination according to claim 1 , wherein the at least one line () comprises a flushing fluid line () for feeding a fluid into the interior of the container () and a prepared fluid line ( claim 1 , ) for guiding the prepared fluid out of the interior of the container () claim 1 , wherein the flushing fluid line () and the prepared fluid line ( claim 1 , ) are formed by one and the same line () or by ...

Infusate caddy for a dialysis system

The invention relates to an infusate caddy for carrying, organizing, and operating infusate containers containing solutes for preparing dialysate and related fluids for use in dialysis. The infusate containers can be seated in the infusate caddy, and the infusate containers removed from the infusate caddy for restocking, cleaning, or resupply, as needed. The infusate caddy can be positioned or seated in a receiving compartment of a dialysis machine, and can also be removed, as needed, from the dialysis machine.

Dialysis priming steps using an infusate caddy

The invention relates to devices, systems, and methods for priming, disinfecting, and preparing dialysate and related fluids for use in dialysis. The dialysate and related fluids can be prepared from solutes obtained from infusate containers seated in an infusate caddy. The infusate caddy can be removably positioned in a receiving compartment of a dialysis machine. Similarly, the infusate containers containing the necessary solutes for preparing the dialysate and related fluids can also be removably positioned in the infusate caddy.

Manifold Diaphragms

The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The manifold includes diaphragms adapted to minimize the dead space between the dialysis machine pins and improve responsivity. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface and a heater in thermal communication with the container. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features. 1. A diaphragm integrated into a disposable manifold for use in a dialysis machine and adapted to be compressed by components that are within said dialysis machine and external to said disposable manifold , said diaphragm comprising: a convex exterior surface protruding outward from the manifold and fixedly attached to said manifold at a first end and at a second end , wherein a distance between the first end and second end defines a length and height of said diaphragm , wherein the diaphragm at the first end and second end has the same height as the manifold , wherein the height of said convex exterior surface increases from said first end to a first height relative to the manifold , and wherein the height of said convex exterior surface decreases from said first height to the second end.2. The diaphragm of claim 1 , wherein the first height of said diaphragm is between 0.03 and 0.04 inches relative to the manifold.3. The diaphragm of claim 1 , wherein the diaphragm has a thickness along the length from the first end to the second end and wherein said thickness is substantially constant along said length.4. The diaphragm of claim 1 , wherein the thickness of ...

PERITONEAL DIALYSATE TEMPERATURE REGULATION SYSTEM

The invention relates to devices, systems, and methods for temperature regulation in generating peritoneal dialysate and using a peritoneal dialysis (PD) system. The system can use a heater and temperature sensors to regulate the temperature of fluid within the PD system. 1. A temperature regulation system for use in peritoneal dialysis , comprising:a first fluid line fluidly connected to a dialysate generation system; the first fluid line including a heater and a first temperature sensor positioned downstream of the heater;the first fluid line fluidly connectable to an integrated cycler through a second fluid line having a second temperature sensor;a control system in communication with the first temperature sensor, the second temperature sensor, and the heater; the control system controlling the heater based on a temperature measured by the first temperature sensor and the second temperature sensor.2. The temperature regulation system of ; wherein the first fluid line is fluidly connected to at least one osmotic agent source downstream of the heater.3. The temperature regulation system of ; further comprising a sterilization module positioned between the first fluid line and the osmotic agent source.4. The temperature regulation system of ; wherein the sterilization module comprises one or more ultrafilters.5. The temperature regulation system of claim 1 , the dialysate generation system fluidly connectable to a disinfectant source.6. The temperature regulation system of claim 5 , the dialysate generation system fluidly connectable to a waste line; the waste line fluidly connectable to the integrated cycler.7. The temperature regulation system of claim 6 , further comprising a system pump; the system pump recirculating fluid from the disinfectant source claim 6 , through the dialysate generation system claim 6 , the temperature regulation system claim 6 , and the second fluid line.8. The temperature regulation system of claim 7 , the control system controlling the ...

DISPOSAL CONTAINER FOR USED DIALYSATE AND EXTRACORPOREAL BLOOD PURIFICATION SYSTEM COMPRISING SAID DISPOSAL CONTAINER

A disposal container for used dialysate including a flexible bag in or at which an inlet connection is formed or arranged which is prepared for connecting the bag to a dialysis machine of the mobile type such that the disposal container is movable or displaceable along with the dialysis machine, wherein the disposal container includes an outlet connection or connector provided separately from the inlet connection, the connector being prepared for connecting the bag to a sewer line in a way sealed against the connector environment; and an extracorporeal blood purification system comprising a stationary system area and a non-stationary system area, the system including a bag according to the invention. 17.-. (canceled)8. A disposal container for used dialysate , the disposal container comprising:a flexible bag;an inlet connection formed or arranged in or at the flexible bag to connect the flexible bag to a mobile dialysis machine such that the disposal container is movable or displaceable along with the mobile dialysis machine; andan outlet connection or connector separate from the inlet connection configured to connect the flexible bag to a sewer line at an end of the flexible bag facing away from the flexible bag such that the flexible bag is sealed against an environment of the outlet connection or connector, wherein the outlet connection or connector is formed integrally with the flexible bag.9. The disposal container according to claim 8 , wherein the outlet connection or connector includes an auxiliary connection via which the outlet connection or connector can be coupled to an auxiliary line that is prepared to ensure an increased emptying rate of dialysate from the flexible bag into the sewer line through pressurization.10. The disposal container according to claim 8 , further comprising:a folding mechanism configured to transmit a compressing force to the flexible bag so as to reduce a volume of the flexible bag to ensure an increased emptying rate of ...

Modular Warming System for Dialysis Fluid

An extremely lightweight and compact heating system greatly increasing patient mobility is provided. The use of a flat plate can be used to greatly decrease package size and weight while providing comparable heat transfer by exploiting the ability of the dialysis bags to conform to this surface and through the greater heating area possible with the flat plate design. A short rim around the plate provides centering and protecting against minor leakage without substantially increasing package height. Protection against leakage is buttressed by sealing the rim to the plate and the use of 12 V only within the heating unit. The result is a lightweight warming device with a short that can be easily transported by the patient greatly improving patient lifestyle and freedom. 1. A warming module for infusible liquids comprising:an upwardly exposed planar metal warming plate sized to receive a flexible polymer bag holding the infusible liquid;a polymer housing supporting the warming plate and providing an upwardly extending peripheral rim presenting a sealed continuous surface between the housing and the warming plate; anda heater element attached to the warming plate to conduct heat through the warming plate and bag into the contained infusible liquid when the bag is held on the warming plate.2. The warming module of wherein the rim may have a height of less than 2 cm.3. The warming module of wherein the rim extends upward from edges of the warming plate by an angle of less than 45°.4. The warming module of wherein the heater is attached to cover at least 90% of the warming plate area.5. The warming module of further including a heater and heater control circuitry claim 1 , and a remote wall adapter providing a voltage less than or equal to 12 V to the heater and heater control circuitry from the remote wall adapter through an adapter cord.6. The warming module of wherein the warming module is less than five pounds.7. The warming module of wherein the rim includes at least ...

DEVICE FOR PREPARING A SOLUTION, IN PARTICULAR IN OR ON A DIALYSIS MACHINE

Devices for preparing a liquid solution are disclosed. The device includes a receptacle defining a cavity for receiving at least one active substance to be dissolved, at least one inlet leading into the cavity for feeding at least one solvent into the cavity, and at least one outlet leading out of the cavity for discharging the liquid solution including the at least one active substance and the at least one solvent from the cavity. The cavity or the receptacle may include a flexible outer shell for enclosing the cavity and an inner, preferably columnar, supporting element for stretching the flexible outer shell between at least two points, the supporting element comprising the at least one inlet at its first end and the at least one outlet at its second end and being enclosed by the flexible outer shell to provide an axially rigid cartridge that can be used in currently customary dialysis machines comprising cartridge connection systems, which can be produced at low cost. 18-. (canceled)9. A device for preparing a liquid solution , comprising:a receptacle defining a cavity for receiving at least one active substance to be dissolved;at least one inlet leading into the cavity for feeding at least one solvent into the cavity; andat least one outlet leading out of the cavity for discharging the liquid solution including the at least one active substance and the at least one solvent from the cavity, wherein the receptacle comprises:a flexible outer shell enclosing the cavity; andan inner supporting element having a first end and a second end for stretching the flexible outer shell between at least two points, the inner supporting element comprising the at least one inlet at the first end and the at least one outlet at the second end and being enclosed by the flexible outer shell, and the supporting element being connected to and/or formed with the at least one inlet and the at least one outlet in one piece.10. The device according to claim 9 , in which the flexible outer ...

Dialysis system including automatic priming

A hemodialysis system comprising: a source of priming fluid; an extracorporeal circuit including an arterial line, a venous line, and a drip chamber; a level sensor operable with the drip chamber; a reversible blood pump operable with the extracorporeal circuit; a connection between the arterial and the venous line; and a priming sequence in which priming fluid from the source is pumped in a reverse pump direction through the extracorporeal circuit and reversibly in a normal pump direction through the extracorporeal circuit, wherein an output from the level sensor is used to determine when to stop pumping in at least one of the directions.

PREPARING AN EXTRACORPOREAL BLOOD TREATMENT APPARATUS

A control system is configured to implement a method of preparing a blood treatment apparatus () for blood treatment. The method comprises installing, by use of a disposable arrangement, first and second flow circuits (C, C) separated by a semi-permeable membrane (), the first flow circuit (C) being connected for fluid communication with the apparatus () and the second flow circuit (C) being connected to form a closed loop that includes a sterilizing filter () and, optionally, a container (). The method further comprises performing backfiltration to transfer a human-compatible fluid from the first flow circuit (C) to the second flow circuit (C) through the semi-permeable membrane (), and circulating () the human-compatible fluid in the closed loop of second flow circuit (C), to thereby sterilize the human-compatible fluid by the sterilizing filter () and, optionally, collect a resulting sterile fluid in the container () for later use. 127-. (canceled)28. A control system for a blood treatment apparatus , said control system comprising:a memory; and instruct an operator to install a first flow circuit for conducting a fluid provided by the blood treatment apparatus through a dialyzer;', 'instruct the operator to install a second flow circuit which is separated from the first flow circuit by a semi-permeable membrane of the dialyzer, the second flow circuit comprising connectors for connection to a vascular system of a subject during blood treatment, wherein the second flow circuit is configured to be disconnected from the vascular system and form a closed loop that includes a sterilizing filter;', 'operate the blood treatment apparatus to pump a human-compatible fluid into the first flow circuit so that a portion of the human-compatible fluid flows through the semi-permeable membrane into the second flow circuit; and', 'operate the blood treatment apparatus to circulate said portion of the human-compatible fluid in the closed loop of the second flow circuit, to ...

Medicament Preparation and Treatment Devices, Methods, and Systems

A medicament preparation system includes a water purification module and a medicament proportioning module that is interoperable with a replaceable fluid circuit. The fluid circuit includes a purified water inlet, a product medicament outlet, and a plurality of pumping tube segments. At least a first concentrate container is connected by at least a portion of the fluid circuit to the product medicament output and a first concentration measurement sensor station is positioned in a flow path. A controller is programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container and the purified water from a signal generated by the first concentration measurement sensor station and to regulate one or both of a first pumping actuator engaged with the first pumping tube segment and a second pumping actuator engaged with the second pumping tube segment, responsively to the concentration of the first concentrate and water. 1. A medicament preparation system for preparing a medicament , comprising:a water purification module with a tap water inlet and a purified water outlet; a purified water inlet that receives purified water from the purified water outlet of the water purification module,', 'a product medicament outlet configured to output the medicament, and', 'a plurality of pumping tube segments, that include a first pumping tube segment and a second pumping tube segment, fluidly connected between the purified water inlet and the product medicament outlet;, 'a medicament proportioning module that is interoperable with a replaceable fluid circuit that includes'}at least a first concentrate container connected by at least a portion of the replaceable fluid circuit to the product medicament output;a first concentration measurement sensor station positioned in a flow path of the replaceable fluid circuit; anda controller programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container ...

DIALYSIS AND METHODS INCLUDING SENSOR FEEDBACK TO IMPROVE PATIENT EXPERIENCE

Peritoneal dialysis, such as automated peritoneal dialysis (“APD”) is provided with any one or more or all of the following sensing or feedback features: impedance sensing to detect peritonitis, temperature sensing to detect peritonitis, bio-MEMS sensing to detect peritonitis, and glucose control for diabetes patients, wherein each sensing or feedback feature analyzes patient effluent fluid or fluid dwelling within a patient's peritoneal cavity. 1. A peritoneal dialysis (“PD”) system comprising:a cycler including a pump actuator and a control unit in operable communication with the pump actuator;a disposable set including a disposable cassette having a pump chamber, the disposable cassette sized and arranged to be held by the cycler such that the pump chamber is in operable communication with the pump actuator, the disposable set including a patient line and a drain line extending from the disposable cassette;a catheter for placement within a patient's peritoneal cavity and for fluid communication with the patient line; andan impedance sensor operably coupled to one of the catheter, patient line, or drain line to sense an impedance of PD fluid residing within the patient, or removed from the patient, the sensed impedance used to detect white blood cells to form a patient peritonitis determination, the control unit configured to communicate the peritonitis determination.2. The PD system of claim 1 , wherein the sensed impedance is sent to the control unit claim 1 , and wherein the control unit is configured to analyze the sensed impedance.3. The PD system of claim 2 , wherein the sensed impedance is sent to the control unit wired or wirelessly.4. The PD system of claim 1 , which includes a network and at least one doctor or clinician computer in communication with the control unit via the network claim 1 , the control unit configured to communicate the peritonitis determination to at least one of a patient or caregiver via a user interface of the cycler or the at ...

Valve Actuation Systems and Related Methods

In one aspect, a valve actuation system includes a drive unit including an actuator configured to engage and move multiple valves disposed within a fluid cassette to selectively open and close each valve of the multiple valves and a positioning frame disposed adjacent the fluid cassette and along which the drive unit can be moved in three dimensions to align the actuator with a selected valve of the multiple valves. 1. A valve actuation system , comprising:a drive unit comprising an actuator configured to engage and move a plurality of valves disposed within a fluid cassette to selectively open and close each valve of the plurality of valves; anda positioning frame disposed adjacent the fluid cassette and along which the drive unit can be moved in three dimensions to align the actuator with a selected valve of the plurality of valves.2. The valve actuation system of claim 1 , wherein the drive unit is carried by the positioning frame.3. The valve actuation system of claim 1 , wherein the actuator is formed to mate with a complementary feature of each of the plurality of valves.4. The valve actuation system of claim 1 , wherein the actuator is configured to be controlled to apply a force to each valve of the plurality of valves to rotate each valve of the plurality of valves.5. The valve actuation system of claim 4 , wherein the actuator is configured to open and close each valve of the plurality of valves.6. The valve actuation system of claim 4 , wherein the force is a rotational force.7. The valve actuation system of claim 1 , wherein the positioning frame further comprises a first linear rail claim 1 , a second linear rail claim 1 , and a third linear rail along which the drive unit can be moved linearly to align the actuator with the selected valve.8. The valve actuation system of claim 7 , wherein the drive unit is configured to traverse the first claim 7 , second claim 7 , and third linear rails in a total time of up to about 0.5 seconds to about 2.0 seconds.9 ...

Dialysis Machines with Integral Salt Solution Chambers and Related Methods

A hemodialysis machine includes a main body and a door connected to the main body. The door and the main body cooperate to define a non-removable chamber. The door is openable relative to the main body of the hemodialysis machine to allow a salt to be placed into the non-removable chamber when the door is in an open position. The main body further includes a fluid inlet, a fluid outlet, and a pumping mechanism. The fluid inlet and the fluid outlet are in fluid communication with the non-removable chamber. The pumping mechanism is configured to deliver a fluid from a fluid source to the non-removable chamber through the fluid inlet to mix with salt within the non-removable chamber to form a salt solution that exits the non-removable chamber through the fluid outlet. 1. A method of preparing a dialysis solution , the method comprising:pouring salt into a non-removable chamber defined between a door and a main body of a hemodialysis machine; andinitiating a dialysis treatment during which a fluid mixes with the salt within the non-removable chamber to form a salt solution.2. The method of claim 1 , further comprising:before pouring the salt into the non-removable chamber, placing a liner into the non-removable chamber of the hemodialysis machine such that initiating the dialysis treatment causes the fluid to enter the liner to form the salt solution,wherein pouring the salt into the non-removable chamber comprises pouring the salt into the liner.3. The method of claim 2 , wherein placing the liner into the non-removable chamber further comprises forming a liquid-tight seal between the liner and the non-removable chamber.4. The method of claim 2 , further comprising:removing the liner from the non-removable chamber.5. The method of claim 1 , further comprising:initiating a cleaning operation of the hemodialysis machine during which a cleaning fluid rinses the non-removable chamber.6. The method of claim 1 , wherein pouring the salt into the non-removable chamber further ...

Apparatus For Extracorporeal Blood Treatment, And Method For Operating An Apparatus For Extracorporeal Blood Treatment

The invention relates to an apparatus for extracorporeal blood treatment that comprises a device for providing fresh dialysate and a drain for used dialysate, a balancing device for balancing fresh dialysate and used dialysate, an ultrafiltration device and a dialyser that is divided into a blood chamber and a dialysate chamber by a semi-permeable membrane The invention further relates to a method for operating such an apparatus for extracorporeal blood treatment. The apparatus according to the invention is based on the use of the ultrafiltration device of the blood treatment apparatus for raising the liquid level in the air separation device on the secondary side of the dialysate system I. In the apparatus according to the invention, the ultrafiltration device is designed such that the ultrafiltration device can be operated not only in an ultrafiltration mode, but also in a ventilation mode. In the ultrafiltration mode, the ultrafiltration device is operated in such a way that used dialysate is removed from the container A of the first air separation device whereas in a ventilation mode the ultrafiltration device is operated in the opposite direction so that used dialysate is supplied into the container A of the first air separation device as a result of which the liquid level D rises in the container of the first air separation device. 1. Apparatus for extracorporeal blood treatment , comprisinga device for providing fresh dialysate and a drain for used dialysate,a balancing device for balancing fresh dialysate and used dialysate,a dialyser, which is divided into a blood chamber and a dialysate chamber by a semi-permeable membrane,a dialysate supply line for fresh dialysate, leading from the device for providing fresh dialysate to an inlet to the dialysate chamber via the balancing device, and a dialysate discharge line for used dialysate, leading from an outlet of the dialysate chamber to the drain via the balancing device,a first air separation device comprising ...

Disposable Cartridge System for Use with Sorbent or Premixed Dialysate

A hemodialysis machine defining a closed loop fluid path for dialysate solution, the fluid path comprising: a first pump chamber having a pump inlet and a pump outlet, a dialyser having a dialyser inlet and a dialyser outlet, a conduit connected between the outlet of the first pump chamber and the inlet of the dialyser, a second pump chamber having a pump inlet and a pump outlet, a conduit connected between the outlet of the dialyser and the inlet of the second pump chamber, a dialysate regeneration device having a filter inlet and a filter outlet, a conduit connected between the outlet of the second pump chamber and the inlet of the dialysate regeneration device, a reservoir having a reservoir inlet and a reservoir outlet, a conduit connected between the outlet of the dialysate regeneration device and the inlet of the reservoir and, a conduit connected between the outlet of the reservoir and the inlet of the first pump chamber. 1. A hemodialysis machine defining a closed loop fluid path for dialysate solution , the hemodialysis machine comprising:a mixing chamber for receiving the dialysate solution;a first flow balance chamber connected to the mixing chamber;a second flow balance chamber connected to the first flow balance chamber;a dialyser for cleaning the dialysate solution, the dialyser connected between the first flow balance chamber and the second flow balance chamber; anda filter for cleaning the dialysate solution, the filter connected between the second flow balance chamber and the mixing chamber;wherein the mixing chamber and first and second flow balance chambers are provided on a cartridge removably mountable in the hemodialysis machine.2. A hemodialysis machine defining a closed loop fluid path for dialysate solution , the hemodialysis machine comprising:a fixed volume of dialysate solution;a mixing chamber for receiving the dialysate solution;a first flow balance chamber connected to the mixing chamber;a second flow balance chamber connected between ...

Balancing Method and Balancing Unit Being Independent of Temperature Disturbance

This disclosure relates to a method for determining a fluid balance between a first volume flow in a first section of a fluid circuit and a second volume flow of a second section of the fluid circuit. The method may also include adjusting, assuming or detecting a first temperature in the first section of the fluid circuit and a second temperature in the second section of the fluid circuit, or detecting a temperature difference between the first and the second sections. The method may also include detecting a second volume flow in a second section of the fluid circuit and forming a balance from at least the first volume flow and a corrected value of the second volume flow. The corrected value is determined from the detected second volume flow and the second temperature and/or the temperature difference. 116.-. (canceled)17. A method for determining a fluid balance between fluid flows in a fluid circuit of a medical functional device , the method comprising:determining a first volume flow in a first section of the fluid circuit;determining a first temperature in the first section of the fluid circuit;determining a second temperature in a second section of the fluid circuit, or determining a temperature difference between the first section and the second section;determining a second volume flow in the second section of the fluid circuit;determining a corrected value of the second volume flow based on the second volume flow and the second temperature or the temperature difference; anddetermining the fluid balance based on the first volume flow and the corrected value of the second volume flow.18. The method according to claim 17 , further comprising:controlling, or generating a signal for controlling, at least one of: (i) a volume flow of the fluid circuit, (ii) a cross-section of at least one section of the fluid circuit, and (iii) a temperature in the fluid circuit,wherein the controlling, or the generating a signal for controlling, is based on the fluid balance, the ...

Peritoneal dialysate purity control system

The invention relates to devices, systems, and methods for generating a peritoneal dialysate having purity and sterility characteristics suitable for Peritoneal Dialysis (PD). The peritoneal dialysate can be generated from water of variable quality using a purity control system having one or more ultrafilters for sterilization of the peritoneal dialysate Peritoneal dialysate generation system and related methods are described that can generate sterilized peritoneal dialysate and deliver peritoneal dialysis therapy to a patient.

Rotary Valves for Dialysis Systems

In one aspect, a dialysis fluid cassette includes an inlet fluid line, multiple outlet fluid lines, and a valve including an actuation feature by which the valve can be rotated to fluidly communicate the inlet fluid line with a selected fluid line of the multiple outlet fluid lines. 1. A dialysis fluid cassette , comprising:an inlet fluid line;a plurality of outlet fluid lines; anda valve comprising an actuation feature by which the valve can be rotated to fluidly communicate the inlet fluid line with a selected fluid line of the plurality of outlet fluid lines.2. The dialysis fluid cassette of claim 1 , wherein the actuation feature comprises a surface profile that is formed to be engaged by an actuator for rotating the valve.3. The dialysis fluid cassette of claim 1 , wherein the actuation feature has a polygonal shape.4. The dialysis fluid cassette of claim 1 , wherein the actuation feature has a symmetric shape.5. The dialysis fluid cassette of claim 1 , wherein the actuation feature has an asymmetric shape.6. The dialysis fluid cassette of claim 1 , wherein the actuation feature comprises a recessed profile.7. The dialysis fluid cassette of claim 1 , wherein the actuation feature comprises a protrusion that extends from a main body of the valve.8. The dialysis fluid cassette of claim 1 , wherein the valve further comprises an indicator having an orientation that corresponds to the selected fluid line.9. The dialysis fluid cassette of claim 1 , wherein the valve further comprises:a valve body defining an internal fluid pathway that can fluidly communicate the inlet fluid line with the selected fluid line; anda spring that is configured to move the valve body to enable or disable an operation of the valve.10. The dialysis fluid cassette of claim 9 , wherein the valve body is movable to:a first position at which the internal fluid pathway is aligned with the inlet fluid line and the plurality of outlet fluid lines to enable the operation of the valve, anda second ...

APPARATUS AND METHOD FOR PREPARING A DIALYSIS SOLUTION

The present invention relates to an apparatus for preparing a dialysis solution, wherein the apparatus has a dialyzate line for conducting a dialysis solution and has means that are configured to discontinuously convey a dialysis solution in the dialyzate line, wherein the apparatus has a conductivity sensor that is arranged to measure the conductivity of the dialysis solution, and wherein the apparatus has a concentrate line opening into the dialyzate line upstream of the conductivity sensor at an addition point and having a concentrate pump and has a concentrate container from which the concentrate pump conveys concentrate into the concentrate line and from this into the dialyzate line, characterized in that the apparatus has a controller that is connected to the conductivity sensor and to the concentrate pump and that is configured to control the concentrate pump such that the conductivity fluctuations over time in the dialysis solution downstream of the addition point are reduced with respect to a continuous concentrate conveying.

HEMODIAFILTRATION SYSTEM WITH DISPOSABLE PUMPING UNIT

A hemodiafiltration system with a disposable pumping unit is disclosed. An example system includes a medical fluid pump actuator, a medical fluid heater, a blood filter and a disposable unit. The example disposable unit includes a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source. The example medical fluid cassette portion is also configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed. The example disposable unit also includes a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion. 1. A hemodiafiltration system comprising:a medical fluid pump actuator;a medical fluid heater;a blood filter; and a medical fluid cassette portion including a medical fluid cassette housing configured to be operatively connected to the medical fluid pump actuator to pump medical fluid through the medical fluid cassette portion when the medical fluid cassette portion is in fluid communication with a medical fluid source, the medical fluid cassette portion configured to be placed in fluid communication with the blood filter and with an extracorporeal circuit communicating with the blood filter, the fluid communication enabling hemodiafiltration to be performed, and', 'a heater bag configured to be placed in operable communication with the medical fluid heater and in fluid communication with the medical fluid cassette portion via a to-heater tube and a from-heater tube, wherein the heater bag is spaceable away from the medical fluid cassette portion, and wherein the medical fluid heater ...

Filtration System for Preparation of Fluids for Medical Applications

A treatment system for performing a treatment on a patient may include a treatment fluid preparation device having a pump connected by a fluid channel to a reservoir of a source fluid, the pump conveying the source fluid from the reservoir, through a filter, and combining the source fluid with a concentrate by pumping the source fluid with the concentrate to form a treatment fluid in a batch container. The treatment fluid preparation device may have a controller that controls a heater, the pump, and a memory. The controller starts the heater to warm the treatment fluid in the batch container at a time that is responsive to the treatment time stored in the memory. The controller also detects a pressure property of the filter to determine its integrity and outputs an indication of a failed batch if the pressure property indicates the integrity of the filter is insufficient. 115.-. (canceled)16. A treatment system for performing a treatment on a patient , the treatment system comprising:a source of fluid;a container for treatment fluid;the source of fluid being connected by a line to convey fluid through a filter and into the container for treatment fluid;the container for treatment fluid being a disposable container that permits flow into and out of it;the treatment system having a controller that controls a pump that regulates the flow of fluid from the source of fluid to the container for treatment fluid.17. The system of claim 16 , wherein the pump is regulated responsively to a measurement of pressure.18. The system of claim 16 , further comprising a controller that controls the administration of heat to the container for treatment fluid.19. The system of claim 16 , further comprising a component that withdraws the treatment fluid from the container for treatment fluid and conveys treatment fluid to and from a patient.20. A system for generating a batch of treatment fluid at a point of use claim 16 , comprising:a fluid circuit having a water source line, a ...

DIALYSIS PRECURSOR COMPOSITION PRODUCT

The present invention concerns a dialysis acid precursor composition for use during preparation of a dialysis acid concentrate solution and for mixing with water, a sodium containing concentrate, and a bicarbonate containing concentrate into a ready-for-use dialysis solution. The dialysis acid precursor composition consists of powder components comprising glucose, at least one dry acid and at least one magnesium salt, and optionally potassium salt, and calcium salt. According to the invention the glucose and the at least one magnesium salt, are present as anhydrous components in the dialysis acid precursor composition. 1. A dialysis acid precursor composition product comprising:an anhydrous powdered composition including a sodium containing concentrate, a bicarbonate containing concentrate, a dry acid and a magnesium salt, and{'sup': '2', 'a sealed moisture-resistant container housing the anhydrous powdered composition, wherein the container has a water vapor transmission rate less than 0.3 g/m/d at 38° C./90% RH.'}2. The dialysis precursor composition product of claim 1 , wherein the dry acid includes at least one of lactic acid claim 1 , citric acid claim 1 , gluconic acid claim 1 , glucono-δ-lactone claim 1 , N-acetyl cysteine and α-lipoic acid.3. The dialysis precursor composition product of claim 1 , wherein the magnesium salt includes at least one of anhydrous magnesium chloride claim 1 , magnesium gluconate claim 1 , magnesium citrate claim 1 , magnesium lactate claim 1 , and magnesium α-ketoglutarate.4. The dialysis precursor composition product of claim 1 , wherein the anhydrous powdered composition includes at least one of calcium chloride dihydrate claim 1 , calcium chloride monohydrate claim 1 , anhydrous calcium chloride claim 1 , calcium gluconate claim 1 , calcium citrate claim 1 , calcium lactate claim 1 , and calcium α-ketoglutarate.5. The dialysis precursor composition product of claim 1 , wherein the water vapor transmission rate is less than 0.2 ...

SPENT DIALYSATE CONTAINER FOR DISPOSING SPENT DIALYSATE IN A DIALYSIS SYSTEM

Dialysis systems for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a spent dialysate container for receiving spent dialysate from a patient. In use, the spent dialysate containers are arranged and configured to provide one or more mechanical advantages to ease disposal of the spent dialysate. For example, the spent dialysate container may receive the spent dialysate from the patient and enable the patient or caregiver to dispose of the spent dialysate without requiring the patient or caregiver to lift bags of spent dialysate or incorporate lengthy drain lines. The spent dialysate container may include a reservoir to receive the spent dialysate, wheels to enable the patient or caregiver to transport the reservoir, mechanisms to facilitate disposal of the spent dialysate from the reservoir, a nozzle to dispose of the spent dialysate, and/or a disinfectant to disinfect the drain. 1. A spent dialysate container , comprising:a reservoir arranged and configured to receive spent dialysate resulting from a dialysis treatment;wheels arranged and configured to enable the spent dialysate container to move; anda pump arranged and configured to evacuate the spent dialysate from the reservoir to facilitate disposal of the spent dialysate.2. The spent dialysate container of claim 1 , wherein the pump comprises a plate pivotably coupled to a base of the spent dialysate container claim 1 , the plate movable from a first position to a second position claim 1 , in the second position claim 1 , the plate compresses the reservoir causing the spent dialysate to evacuate the reservoir.3. The spent dialysate container of claim 2 , further comprising a lever arranged and configured to move the plate between the first and second positions.4. The spent dialysate container of claim 1 , wherein one or more of the wheels are motorized to facilitate motorized movement of the spent dialysate ...

EXTRACORPOREAL CIRCULATION CASSETTE

This extracorporeal circulation cassette is provided with: a blood circuit () comprising a flexible tube and having a blood tube access portion set in a predetermined position in a device; a dialysate circuit () comprising a flexible tube and having a dialysate tube access portion set in a predetermined position in the device; a first panel () and a second panel () that are rigid and that integrate the blood circuit () and the dialysate circuit () while sandwiching the blood circuit () and the dialysate circuit () from both sides; and a window portion formed in a part of at least one of the first panel () and the second panel (), disposed in a predetermined position in the device. The blood tube access portion and the dialysate tube access portion are positioned in the window portion. 1. An extracorporeal circulation cassette , comprising:a blood circuit formed of a flexible tube and including a blood tube access portion which is set at a predetermined position of an apparatus;first and second panels unified with each other by sandwiching the blood circuit from both sides and having rigidity; anda window formed at a portion disposed at the predetermined position of at least one of the first and second panels of the apparatus, whereinthe blood tube access portion of the blood circuit stored in a space formed by the first and second panels is disposed at the window.2. The extracorporeal circulation cassette according to claim 1 , whereinthe portion disposed at the predetermined position of the apparatus is inserted into the apparatus.3. The extracorporeal circulation cassette according to claim 1 , whereinat least part of the portion other than the blood tube access portion of the blood circuit is disposed in the space formed by the first and second panels.4. The extracorporeal circulation cassette according to claim 1 , further comprising:a dialysate circuit formed of a flexible tube and including a dialysate tube access portion which is set at the predetermined ...

SIEVE-LIKE FILTER UNIT FOR CARTRIDGE-SHAPED RECEPTACLE

A sieve-like filter unit, especially for a cartridge-shaped receptacle, which is arranged on a connecting port/connector of the receptacle and is designed to withhold undissolved powder and/or solid particles present in the receptacle, comprising at least two openings each being composed of at least two connected part recesses, wherein each individual opening in its entirety is formed to be extending in a non-linear manner. 111.-. (canceled)12. A sieve-like filter unit for a cartridge-shaped receptacle to be arranged on a connecting port of the cartridge-shaped receptacle , the sieve-like filter unit configured to withhold at least one of undissolved powder or solid particles present in the cartridge-shaped receptacle , the sieve-like filter unit comprising:at least two openings, each opening composed of at least two connected part recesses, wherein a non-linear run of the opening is provided in a transition area between at least two of the at least two part recesses such that each opening extends in a non-linear manner.13. The sieve-like filter unit according to claim 12 , wherein the at least two connected part recesses extend away from a common point in at least two non-parallel directions.14. The sieve-like filter unit according to claim 12 , wherein each of the openings at least one of spans a circle or an extension of the opening in a first direction is identical to an extension of the opening in a second direction.15. The sieve-like filter unit according to claim 12 , wherein each of the at least two openings are at least one of star-shaped or radiant and have at least two beams and/or spikes each extending radially outwardly from a common point.16. The sieve-like filter unit according to claim 15 , wherein the common point is at least one of an opening center point claim 15 , a transition point claim 15 , or an intersection point between the at least two connected part recesses.17. The sieve-like filter unit according to claim 12 , wherein each of the at ...

Modular assembly for a portable hemodialysis system

A modular assembly for a portable hemodialysis system may include a dialysis unit, e.g., that contains suitable components for performing hemodialysis, such as a dialyzer, one or more pumps to circulate blood through the dialyzer, a source of dialysate, and one or more pumps to circulate the dialysate through the dialyzer, and a power unit having a housing that contains suitable components for providing operating power to the pumps of the dialysis unit. The power unit may be selectively connected to the dialysis unit and provide power (e.g., pneumatic power in the form of pressure and/or vacuum) to the dialysis unit for the pumps when connected to the dialysis unit, but may be incapable of providing power to the dialysis unit when disconnected from the dialysis unit. The dialysis unit and the power unit are sized and weighted to each be carried by hand by a human.

Implantable fluid management system for treating heart failure

A device and methods for treating renal failure are disclosed. One embodiment of the device is an implantable peritoneal dialysis device. When in use, the device can have a semi-permeable reservoir implanted in the peritoneal cavity. The reservoir can receive blood waste and drain through one or more conduits, via a pump, to the biological bladder. Solids and/or a solution benefiting dialysis can be pumped to the reservoir and/or implanted in the peritoneal cavity.

Medical treatment system and methods using a plurality of fluid lines

Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of a diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater. Improvements are also disclosed in the application of negative pressure during a drain phase in peritoneal dialysis therapy, and to control the amount of intraperitoneal fluid accumulation during a therapy. Improvements in efficiency are also disclosed in the movement of fluid into and out of a two-pump cassette and heater bag of a peritoneal dialysis cycler, and in the synchronization of the operation of two or more pumps in a peritoneal dialysis cycler or other fluid handling devices using a multi-pump arrangement.

Manifold Diaphragms

The specification discloses a portable dialysis machine having a detachable controller unit and base unit. The controller unit includes a door having an interior face, a housing with a panel, where the housing and panel define a recessed region configured to receive the interior face of the door, and a manifold receiver fixedly attached to the panel. The manifold includes diaphragms adapted to minimize the dead space between the dialysis machine pins and improve responsivity. The base unit has a planar surface for receiving a container of fluid, a scale integrated with the planar surface and a heater in thermal communication with the container. Embodiments of the disclosed portable dialysis system have improved structural and functional features, including improved modularity, ease of use, and safety features. 1. A diaphragm integrated into a disposable manifold for use in a dialysis machine and adapted to be compressed by components that are within said dialysis machine and external to said disposable manifold , said diaphragm comprising: a convex exterior surface protruding outward from the manifold and fixedly attached to said manifold at a first end and at a second end , wherein a distance between the first end and second end defines a length and height of said diaphragm , wherein the diaphragm at the first end and second end has the same height as the manifold , wherein the height of said convex exterior surface increases from said first end to a first height relative to the manifold , and wherein the height of said convex exterior surface decreases from said first height to the second end.2. The diaphragm of claim 1 , wherein the first height of said diaphragm is between 0.03 and 0.04 inches relative to the manifold.3. The diaphragm of claim 1 , wherein the diaphragm has a thickness along the length from the first end to the second end and wherein said thickness is substantially constant along said length.4. The diaphragm of claim 1 , wherein the thickness of ...

Dialysis systems including therapy prescription entries

A dialysis system includes a dialysis machine configured to control fluid loss or ultrafiltration (“UF”) volume over a treatment; a graphical user interface (“GUI”) that allows selection of a prescription entry for the treatment; and a processor operating with the GUI, the processor programmed to (i) receive a plurality of prescription entries via a local or wide area mode of data communication, each prescription entry including at least one prescribed parameter for operating the dialysis machine to control the fluid loss or UF volume, and (ii) enable an operator to choose between the prescription entries provided at the GUI, and select one of the prescription entries for the treatment.

IN-LINE HEATING OF DIALYSIS FLUIDS

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments are disclosed. The dialysis system may include a dialysis machine for transferring dialysate to a patient from a dialysate source. The dialysate may flow from the dialysate source through a cartridge or cassette (e.g., a disposable cartridge or cassette) positionable within the dialysis machine. The cassette includes a fluid flow channel. The dialysis machine includes a heating chamber for in-line heating of the dialysate in the fluid flow channel. The fluid flow channel is arranged and configured to provide turbulent flow of the dialysate through the fluid flow channel to provide increased heat transfer from the heating chamber to the dialysate. 1. A dialysis system for conducting a dialysis treatment , comprising:a dialysis machine for transferring dialysate to a patient from a dialysate source, the dialysis machine including a cavity and a heating chamber to heat the dialysate to a predetermined temperature; anda disposable cassette positionable within the cavity, the cassette being in fluid communication with the patient and the dialysate source, the cassette including a fluid flow channel;wherein the fluid flow channel is arranged and configured to provide turbulent flow of dialysate through the fluid flow channel to provide increased heat transfer from the heating chamber to the dialysate.2. The dialysis system of claim 1 , wherein the fluid flow channel is arranged and configured to achieve a Reynold's Number (Nr) of 4 claim 1 ,000 or greater.3. The dialysis system of claim 1 , wherein the fluid flow channel is arranged and configured with a cross-sectional area of between 1.0 mmand 2.1 mm.4. The dialysis system of claim 1 , wherein the fluid flow channel has a width of approximately 2 mm and a height of approximately 1 mm.5. The dialysis system of claim 1 , wherein the fluid flow channel includes a plurality of projections ...

Hemodialysis system including a disposable cassette

A dialysis system includes a dialyzer, a sorbent cartridge configured to clean used dialysate from the dialyzer, a dialysate pump actuator configured to pump dialysate to the dialyzer, and a conductivity sensor located adjacent to a temperature sensor. The dialysis system also includes a disposable cassette configured to carry dialysate pumped by the dialysate pump actuator. The disposable cassette includes a combined conductivity and temperature sensor fluid chamber separate from the conductivity sensor and the temperature sensor and located so as to operate with the conductivity sensor and the temperature sensor, respectively, when mounted for operation.

Dry Acid Concentrate In Granulate Form

The present invention relates to a novel dry acid concentrate (DAC) for a dialysis liquid and to a dialysis liquid, which is made from said concentrate, and which may be used for purifying blood. The invention further relates to a method of making the dry acid concentrate as well as the dialysis liquid. It also relates to a container () comprising said acid concentrate, and which is—in certain embodiments—specially adapted to a dialysis unit. 115-. (canceled)16. A dry concentrate suitable to form a liquid acid concentrate or a part of a liquid acid concentrate usable in dialysis comprisinga first component comprising a first granulate comprising a plurality of first granules comprising sodium chloride and glucose, anda second component comprising a second granulate comprising a plurality of second granules, wherein said second granules comprise at least one further physiologically acceptable electrolyte, which is different from sodium chloride,or a second component in the form of a powder, wherein said powder comprises at least one further physiologically acceptable electrolyte which is different from sodium chloride, andwherein said powder comprises a plurality of fine particles, wherein each particle comprises or consists of one of said at least one further physiologically acceptable electrolyte,or a mixture of said second granulate and said powder;wherein said concentrate is substantially free of a base component that is suitably used in dialysis.17. The dry concentrate according to claim 16 , wherein the first and the second components comprise or consist of said first and second granulates.18. The dry concentrate according to claim 17 , wherein the first granules of the first component exhibit a higher average equivalent diameter than the second granules of the second component.19. The dry concentrate according to claim 16 , wherein the first granulate comprises at least 50 wt-% of first granules claim 16 , respectively based on the total weight of the first ...

Method For Treating Dialysate, Dialysis System, And Method For Pre-Evaluating Dialysis Patients For Treatment With Same

A method for treating dialysate solutions used in dialysis wherein dialysate is treated in an early part of a dialysis treatment session by external infusion of bicarbonate solution into the dialysate circuit to eliminate the need for bicarbonate requirements in concentrates used for preparation of precursor dialysate (priming) solutions and/or for a solid bicarbonate layer in a sorbent cartridge. Dialysate is treated in a latter part of a dialysis treatment session by introduction of sterile dilution water to reduce sodium concentration in the dialysate. The method provides a more efficient and reduced use of dialysate fluids, electrolytes, sorbent cartridge materials, equipment scale, or any combinations of these, while maintaining purity standards and applicable physiological ranges for bicarbonate, sodium, and other dialysate solution components over the course of a dialysis treatment session. 1. A method of treating dialysate comprising:a) passing spent dialysate received from a dialyzer through a sorbent cartridge to produce regenerated dialysate that is discharged from the sorbent cartridge for circulation back to the dialyzer;b) introducing bicarbonate solution into the regenerated dialysate during a first dialysis treatment time period to provide a treated regenerated dialysate that is circulated to the dialyzer;c) adding sterile water to the regenerated dialysate during a second dialysis treatment time period occurring after the first dialysis treatment time period to provide a diluted regenerated dialysate that is circulated to the dialyzer.2. The method of claim 1 , wherein the first dialysis treatment time period occurs within an initial 50% of total dialysis treatment time of a dialysis treatment session claim 1 , and the second dialysis treatment time period occurs within a final 50% of the total dialysis treatment time of the same dialysis treatment session.3. The method of claim 1 , wherein the introducing of the bicarbonate solution into the ...

A SYSTEM AND A METHOD FOR PRODUCING MICROBIOLOGICALLY CONTROLLED FLUID

A method and a system () comprising an integrated water purifying apparatus () with a pre-filter circuit () including a particle filter and an activated carbon filter arranged to produce pre-treated water; a fluid circuit () arranged to receive pre-treated water from the pre-filter circuit (), the fluid circuit () includes an RO-pump () and a Reverse Osmosis, RO, device, () arranged to produce purified water; a heating device () arranged to heat purified water from the RO device () to a temperature above 65°; the water purifying apparatus () is further arranged to heat disinfect the fluid circuit () using the heated purified water. The system () further comprises a line set () connected to the purified water outlet connector () at a water line connector () of the line set (), wherein the line set () includes at least one sterile sterilizing grade filter () arranged to filter the purified water into sterile purified water. 117-. (canceled)18. A system comprising:a line set connected to a purified water outlet connector, wherein the line set includes at least one sterilizing filter; and (i) a pre-filter circuit connected to a water inlet for receiving water from a water source, wherein the pre-filter circuit includes a particle filter and an activated carbon filter, wherein each of the particle filter and the activated carbon filter are arranged to filter water received via the water inlet to produce pre-treated water,', a pump,', 'a reverse osmosis device, and', 'a heating device arranged to heat purified water output from the reverse osmosis device to a temperature above 65° C., and, '(ii) a fluid circuit arranged to receive pre-treated water from the pre-filter circuit and to produce purified water, wherein the fluid circuit includes'}, '(iii) the purified water outlet connector,, 'a water purifying apparatus fluidly connected with the line set, the water purifying apparatus including'} pump pre-treated water through the reverse osmosis device using the pump,', ' ...

Filtration System for Preparation of Fluids for Medical Applications

A treatment system for performing a treatment on a patient may include a treatment fluid preparation device having a pump connected by a fluid channel to a reservoir of a source fluid, the pump conveying the source fluid from the reservoir, through a filter, and combining the source fluid with a concentrate by pumping the source fluid with the concentrate to form a treatment fluid in a batch container. The treatment fluid preparation device may have a controller that controls a heater, the pump, and a memory. The controller starts the heater to warm the treatment fluid in the batch container at a time that is responsive to the treatment time stored in the memory. The controller also detects a pressure property of the filter to determine its integrity and outputs an indication of a failed batch if the pressure property indicates the integrity of the filter is insufficient.

HYDROPHOBIC FILTERS FOR AIR MANAGEMENT IN DIALYSIS MACHINES

Dialysis systems and methods for operating dialysis machines (e.g., peritoneal dialysis machines) for conducting dialysis treatments, may include a dialysis machine for transferring dialysate to a patient from a dialysate bag, and a warmer pouch for flowing the dialysate through to heat to a predetermined temperature before flowing into the patient. The dialysate may flow from the dialysate bag through the warmer pouch for pumping into the patient via tubing. A filter may be coupled to the warmer pouch, and the filter may be configured to filter out air content from the dialysate. 1. A dialysis system for conducting a dialysis treatment , comprising:a dialysis machine for transferring dialysate to a patient from a dialysate bag;a warmer pouch for flowing the dialysate through to heat to a predetermined temperature before flowing into the patient, the dialysate flowing from the dialysate bag through the warmer pouch for pumping into the patient via tubing; anda filter coupled to the warmer pouch, the filter configured to filter out air content from the dialysate.2. The dialysis system according to claim 1 , wherein the filter is a hydrophobic filter.3. The dialysis system according to claim 1 , wherein the filter is coupled to an inlet of the warmer pouch claim 1 , such that the air content is removable before flowing through the warmer pouch.4. The dialysis system according to claim 1 , wherein the filter includes a hydrophobic membrane.5. The dialysis system according to claim 4 , wherein a negative pressure chamber is disposed exterior to the hydrophobic membrane claim 4 , such that the air content is flowable to the negative pressure chamber from an area of positive pressure in the filter.6. The dialysis system according to claim 3 , further comprising a second filter coupled to an outlet of the warmer pouch.7. The dialysis system according to claim 1 , wherein the filter is coupled to the warmer pouch by the tubing connecting to the dialysate bag for ...

PERITONEAL DIALYSIS SYSTEM INCLUDING A WATER TREATMENT DEVICE

A peritoneal dialysis system is disclosed. An example peritoneal dialysis system includes a water treatment device including a water treatment processor and a first memory and a peritoneal dialysis (“PD”) machine including a PD processor and a second memory. The PD machine is configured to mix water treated by the water treatment device with at least one concentrate to produce a peritoneal dialysis fluid for treatment. The example peritoneal dialysis system also includes a data link between the water treatment processor and the PD processor. The water treatment device is configured to prepare an amount of treated water and, upon communication between the water treatment processor and PD processor over the data link, deliver the amount of the treated water to the PD machine for use in mixing the peritoneal dialysis fluid for the treatment. The treated water has a purity corresponding to an injectable quality or a sterile quality. 1. A peritoneal dialysis system comprising:a water treatment device including a water treatment processor and a water treatment memory;a peritoneal dialysis (“PD”) machine including a PD processor and a PD memory, the PD machine configured to mix water treated by the water treatment device with at least one concentrate to produce a peritoneal dialysis fluid for treatment; anda data link between the water treatment processor and the PD processor,wherein (i) the PD processor uses instructions stored in the PD memory to determine a treated water flowrate and send the treated water flowrate via the data link to the water treatment processor or (ii) the PD processor uses the instructions stored in the PD memory to send a parameter via the data link to the water treatment processor, wherein the water treatment processor determines the treated water flowrate from the parameter, and wherein the water treatment processor causes the water treatment device to deliver treated water to the PD machine at the treated water flowrate.2. The peritoneal ...

Medical treatment system and methods using a plurality of fluid lines

A medical treatment system, such as peritoneal dialysis system, may include control and other features to enhance patient comfort and ease of use. For example, a peritoneal dialysis system may include a control system that can adjust the volume of fluid infused into the peritoneal cavity to prevent the intraperitoneal fluid volume from exceeding a pre-determined amount. The control system can adjust by adding one or more therapy cycles, allowing for fill volumes during each cycle to be reduced. The control system may continue to allow the fluid to drain from the peritoneal cavity as completely as possible before starting the next therapy cycle. The control system may also adjust the dwell time of fluid within the peritoneal cavity during therapy cycles in order to complete a therapy within a scheduled time period. The cycler may also be configured to have a heater control system that monitors both the temperature of a heating tray and the temperature of a bag of dialysis fluid in order to bring the temperature of the dialysis fluid rapidly to a specified temperature, with minimal temperature overshoot.

BLOOD CIRCUIT ASSEMBLY FOR A HEMODIALYSIS SYSTEM

A blood circuit assembly for a dialysis unit may include an organizing tray, a pair of pneumatic pumps mounted to the organizing tray for circulating blood received from a patient through a circuit including a dialyzer unit and returned to the patient, an air trap mounted to the organizing tray arranged to remove air from blood circulating in the circuit, a pair of dialyzer connections arranged to connect to the inlet and outlet of a dialyzer unit, and a pair of blood line connectors, one inlet blood line connector for receiving blood from the patient and providing blood to the pneumatic pumps and the other outlet blood line connector for returning blood to the patient. 1. A blood circuit assembly for a dialysis unit , comprising:an organizing tray;a pair of pneumatic pumps mounted to the organizing tray for circulating blood received from a patient through a circuit including a dialyzer unit and returned to the patient;an air trap mounted to the organizing tray arranged to remove air from blood circulating in the circuit;a pair of dialyzer connections arranged to connect to the inlet and outlet of a dialyzer unit; anda pair of blood line connectors, one inlet blood line connector for receiving blood from the patient and providing blood to the pneumatic pumps and the other outlet blood line connector for returning blood to the patient.2. The blood circuit assembly of claim 1 , further comprising an anticoagulant connection for engaging with an anticoagulant source and providing anticoagulant into the circuit.3. The blood circuit assembly of claim 2 , further comprising a pump for pumping anticoagulant from the anticoagulant source to the circuit.4. The blood circuit assembly of claim 3 , wherein the pair of pneumatic pumps claim 3 , the anticoagulant connection claim 3 , and the anticoagulant pump are part of a pump cassette.5. The blood circuit assembly of claim 4 , wherein the inlet blood line connector is connected to an inlet for the pump cassette claim 4 , an ...

SYSTEMS WITH DISPOSABLE PUMPING UNIT

An embodiment of a peritoneal dialysis system includes a peritoneal dialysis hardware unit having a housing with a first opening, a door coupled to the housing and having a second opening, and a solid pump piston having a solid piston shaft attached to or integrally formed with a solid piston head. The system also includes a stepper motor operable to cause the solid pump piston to translate; a disposable pumping unit having a first and a second opposing surface, and a fluid pump receptacle extending from the first and second surface to fit within the second opening. The hardware unit and pumping unit are structured and arranged to allow the pumping unit to be placed into the hardware unit such that the fluid pump receptacle is aligned with the first opening, the second opening, and the solid piston head when the door is closed against the housing. 1. A peritoneal dialysis system comprising: a housing defining a first opening, and', 'a door coupled to the housing, the door defining a second opening;, 'a peritoneal dialysis hardware unit including'} a first surface,', 'a second surface opposite the first surface, and', 'a fluid pump receptacle extending from the first surface and the second surface so as to fit within the second opening defined in the door of the peritoneal dialysis hardware unit; and, 'a disposable pumping unit including'}wherein the peritoneal dialysis hardware unit and the disposable pumping unit are structured and arranged to allow the disposable pumping unit to be placed into the peritoneal dialysis hardware unit such that the fluid pump receptacle is aligned with both the first opening and the second opening when the door is closed against the housing.2. The peritoneal dialysis system of claim 1 , wherein at least one of the first opening and the second opening is defined as a clamshell claim 1 , and wherein the disposable pumping unit is structured so that the fluid pump receptacle fits into the opening of the clamshell.3. The peritoneal ...

AUTOMATED PERITONEAL DIALYSIS SYSTEM USING STEPPER MOTOR

An embodiment of a peritoneal dialysis system includes an enclosure, a door hingedly attached to the enclosure, a stepper motor housed by the enclosure, a solid pump piston in operable communication with the stepper motor and including a solid pump shaft attached to or integrally formed with a solid pump head, and a disposable unit contacting the enclosure and the door. The disposable unit includes a moveable membrane operable with the solid pump head. The stepper motor is configured to move the solid pump head towards and away from the disposable unit. The system further includes a position detection apparatus operable with the stepper motor and located to provide an output indicative of a position of the solid pump head relative to a reference position. 1. A peritoneal dialysis system comprising:an enclosure;a stepper motor housed by the enclosure;a solid pump piston including a solid piston shaft attached to or integrally formed with a solid pump head, the solid pump piston in operable communication with the stepper motor;a disposable unit including at least one flexible membrane attached to a rigid piece, the enclosure and the disposable unit structured and arranged to allow the flexible membrane to move beyond a relaxed position of the flexible membrane, the enclosure structured and arranged to receive the disposable unit such that the stepper motor can move the solid pump head towards and away from the disposable unit to allow (i) the flexible membrane to move outwardly from the rigid piece as the solid pump head is moved away from the disposable unit, and (ii) the flexible membrane to move within the rigid piece as the solid pump head is moved towards the disposable unit; andan encoder operable with the stepper motor, the encoder configured to provide an output indicative of a position of the solid pump head after the solid pump head has moved towards or away from the disposable unit.2. The peritoneal dialysis system of claim 1 , which includes a controller ...

TREATMENT FLUID PREPARATION SYSTEM

A system for purifying incoming fluid is provided that is modular and includes a heat exchanger module, an evaporator-condenser module and a compressor. The system is configured to facilitate passive drainage of the purified fluid for collection. The system components are arranged in a stacked configuration to facilitate gravitational flow of the purified fluid such that the purified fluid drains passively for collection. A system for preparation of ready-to-use treatment fluid is also provided including the modular fluid purification system, a preparation station and a coupling device. The components are configured to be retained in a portable carrier that is manually operable for improved access to and mobility of the components. A coupling device for use in connecting flow channels of a plurality of components and for use in preparing ready-to-use dialysate is also provided, A further system for preparation of a receptacle and a ready-to-use treatment fluid in the receptacle is also provided. 1. A coupling device for connecting flow channels of a plurality of components and for preparing ready-to-use treatment fluid , the coupling device comprising a plurality of interconnected internal channels , each channel having a first coupling zone and a second coupling zone recessed in the channel relative to the first coupling zone , wherein each channel is configured for two stage connection with a respective component , and the coupling device is configured for sterile interconnection of the flow channels of the plurality of components for passage of fluids therebetween.2. The coupling device of claim 1 , wherein:(a) the first stage is a sterilisation stage in which respective ones of the components are in sealing physical contact with the first coupling zone but not with the second coupling zone; and(b) the second stage is a coupling stage in which ones of the components are physically coupled with a respective one of the device channels at the sterilised second ...

CASSETTE SYSTEM INTEGRATED APPARATUS

A cassette integrated system. The cassette integrated system includes a mixing cassette, a balancing cassette, a middle cassette fluidly connected to the mixing cassette and the balancing cassette and at least one pod. The mixing cassette is fluidly connected to the middle cassette by at least one fluid line and the middle cassette is fluidly connected to the balancing cassette by at least one fluid line. The at least one pod is connected to at least two of the cassettes wherein the pod is located in an area between the cassettes. 18.-. (canceled)9. A fluid balancing cassette comprising:a first fluid flowpath and a separate, second fluid flowpath, each said first fluid flowpath and second fluid flowpath having a separate inlet to the cassette and a separate outlet from the cassette;a first fluid balancing pod having a fixed first total fluid volume and comprising a flexible membrane separating a first chamber from a second chamber, the sum of a first chamber volume plus a second chamber volume equal to the fixed first total fluid volume;the first chamber connected to the first fluid flowpath between a first fluid flowpath inlet valve and a first fluid flowpath outlet valve, and the second chamber connected to the second fluid flowpath between a second fluid flowpath inlet valve and a second fluid flowpath outlet valve;wherein said valves are pneumatically actuated membrane valves, and the first fluid flowpath inlet valve and the second fluid flowpath outlet valve are ganged together by being connected via a common actuation port or pneumatic line at a single pneumatic pressure to a pneumatic supply source able to controllably pressurize the common actuation port or pneumatic line to the single pneumatic pressure to actuate both the first fluid flowpath inlet valve and the second fluid flowpath outlet valve at the same time.101. The fluid balancing cassette of claim , further comprising a second fluid balancing pod having a fixed second total fluid volume and ...

DIALYSIS SYSTEM AND METHODS

Dialysis systems and methods are described which can include a number of features. The dialysis systems described can be to provide dialysis therapy to a patient in the comfort of their own home. The dialysis system can be configured to prepare purified water from a tap water source in real-time that is used for creating a dialysis fluid solution. The dialysis systems described also include features that make it easy for a patient to self-administer therapy. 1. A method of providing dialysis therapy , comprising the steps of:fluidly coupling a disposable container to a dialysis machine with a single connection interface, the disposable container including at least one compartment having a powdered dialysis fluid component therein and at least one compartment having a liquid dialysis fluid component therein;connecting a blood tubing set of the dialysis machine to a patient;initiating dialysis therapy;delivering a purified water into the at least one compartment having the powdered dialysis fluid component;generating dialysis fluid in real-time from the disposable container; andinitiating dialysis therapy with the dialysis fluid.2. The method of claim 1 , further comprising:detecting a condition of the patient; andadjusting proportioning of the dialysis fluid in real-time.3. The method of claim 1 , wherein mounting the disposable container further comprises attaching a connector-side interface of the disposable container to a corresponding machine-side interface on the dialysis machine.4. The method of claim 2 , wherein detecting a condition further comprises measuring at least one parameter of the patient's health or the patient's blood.5. The method of claim 2 , wherein the condition comprises a state of electrolytes in the patient's blood.6. The method of claim 2 , wherein adjusting proportioning further comprises increasing a concentration of at least one dialysis fluid component from the disposable container.7. The method of claim 6 , wherein increasing a ...

Balancing Unit Being Independent of Temperature Disturbance and Balancing Method

The disclosure relates to a functional device, in particular a medical functional device, having at least one fluid circuit. The fluid circuit comprises at least one heat exchange device being arranged and/or embodied between a first section of the fluid circuit and a second section of the fluid circuit. The disclosure relates further to a balancing unit, a treatment apparatus, and a balancing method. 116.-. (canceled)17. A medical device , comprising a fluid circuit or one section thereof , wherein the medical device or the fluid circuit comprises a heat exchange device or is connected thereto , wherein the heat exchange device is arranged between a first section of the fluid circuit and a second section of the fluid circuit.18. The medical device according to claim 17 , wherein the heat exchange device is configured to balance a temperature of fluid in the first section and a temperature of fluid in the second section claim 17 , or the heat exchange device is configured such that a temperature difference of the fluids in the first and second sections is at least reduced before and after exiting the heat exchange device.19. The medical device according to claim 17 , wherein the heat exchange device comprises a heat conducting body claim 17 , and wherein a section of the fluid circuit extends along or is arranged in the heat conducting body.20. The medical device according to claim 17 , wherein the heat exchange device is a separate claim 17 , substitutable claim 17 , or interchangeable device which is releasable from the medical device as a disposable item.21. The medical device according to claim 17 , wherein the medical device is configured to be connected or connectable to a flow sensor or comprises a flow sensor claim 17 , wherein the flow sensor is arranged to measure a volume flow in either the first section or the second section claim 17 , or in both of the first section and the second section of the fluid circuit.22. The medical device according to claim 21 ...

Blood purification machine comprising heated fluid circuit

A machine for extracorporeal blood treatment comprising a machine-side fluid circuit is disclosed. The machine comprises a heat exchanger for heating cold purification fluid freshly supplied on its intake side, for which purpose used still warm purification fluid flows past its opposite discharge side for a heat exchange, and a circulation valve for changing over between a blood purification mode in which the used purification fluid is disposed of in an open fluid circuit through the discharge side of the heat exchanger into a drain and a disinfection mode in which hot disinfectant is circulated in a closed circuit. The circulation valve is connected downstream of the heat exchanger with respect to the discharge side thereof.

Container and connector for providing a medical solution

A container for mixing an enclosed medical agent with a fluid. The container comprising an inclining bottom seam directed towards a connector. The connector comprising an elongated hollow body having a plurality of interconnected walls defining a first and a second longitudinal flow channel for fluidly connecting an inside and an outside of the container. The first flow channel has a first opening and a second opening, the first opening of the first flow channel is devised to be arranged inside of the container and the second opening of the first flow channel is devised to be arranged outside the container. The first opening of the first flow channel is arranged radially outwards from the first flow channel and directed towards said inclined bottom seam. The second flow channel has a first opening devised to be arranged inside of said container and a second opening devised to be arranged outside the container arranged axially to the first opening of the second flow channel.

FLUID CIRCUIT FOR DELIVERY OF RENAL REPLACEMENT THERAPIES

A portable dialysis cabinet for use in dialysis. The portable dialysis cabinet can have a size and weight that facilitates easy movement of the cabinet from one location to another with relative ease. The portable dialysis cabinet can have additional features necessary to facilitate portability, such as wheels and a handle. In general, the portable dialysis cabinet can contain all the necessary components for performing a dialysis session. 1. A portable dialysis cabinet , comprising:a dialysis system;at least two wheels disposed on a bottom surface of the dialysis cabinet;a first pair of opposing doors hingeably disposed on the dialysis cabinet creating when said doors are closed a first and second interior portions of the dialysis cabinet, the first pair of opposing doors having a first door connected to the dialysis cabinet by a first hinge on a front left side of the dialysis cabinet and a second door connected to the dialysis cabinet by a second hinge on a front right side of the dialysis cabinet, wherein the first door opens by swinging about a first vertical axis defined by a the first hinge on the left side of the dialysis cabinet and the second door opens by swinging about a second vertical axis defined by the second hinge on front right side of the dialysis cabinet; wherein the first door and second door are in contact when the first door and second door are closed; wherein the first and second interior portions are occupied by one or more interior components when closed; andat least one mounting surface for mounting a sorbent cartridge on a base of at least one of the first and second doors.2. The portable dialysis cabinet of claim 1 , further comprising at least a second mounting surface for mounting a reservoir on at least one of the first and second doors.3. The portable dialysis cabinet of claim 1 , wherein the first pair of opposing doors in an opened configuration provide access to one or more fluid connection ports located on a main body of the base ...

DIALYSATE SUPPLY DEVICE AND BLOOD DIALYZING APPARATUS HAVING THE SAME

Provided is a dialysate supply device and a blood dialyzing apparatus including the same. The dialysate supply device includes a flow controller controlling a dialysate flow, a supply pump supplying dialysate to a hemodialyzer, a recovery pump discharging dialysate from the hemodialyzer, a volume chamber storing dialysate, and a pressure-relief bypass maintaining dialysate pressure within a permissible range. The blood dialyzing apparatus includes the dialysate supply device, a blood tube, and a one-way valve disposed on the blood tube. The blood dialyzing apparatus can quickly change dialysate pressure in the hemodialyzer using the dialysate supply device having the flow controller, cylinder and piston, and increase mass transfer and hemodialysis efficiency. Also, the blood dialyzing apparatus may be miniaturized and lightened to provide a portable blood dialyzing apparatus because blood is transferred without using a blood pump. 1. A dialysate supply device supplying and discharging dialysate , the dialysate supply device comprising:a supply pump supplying dialysate to a hemodialyzer;a recovery pump discharging dialysate of the hemodialyzer;a flow controller controlling a dialysate flow through a first dialysate tube connected to the supply pump through which dialysate is supplied to the supply pump, a second dialysate tube connecting the supply pump and the hemodialyzer through which dialysate of the supply pump is supplied to the hemodialyzer, a third dialysate tube connecting the hemodialyzer and the recovery pump through which dialysate of the hemodialyzer is discharged to the recovery pump, and a fourth dialysate tube connected to the recovery pump through which dialysate of the recovery pump is discharged; anda volume chamber connected to the third dialysate tube or the second dialysate tube.2. The dialysate supply device of claim 1 , wherein the supply pump and the recovery pump comprise:a cylinder having an internal space;a piston reciprocally disposed ...

Medical Treatment System and Methods Using a Plurality of Fluid Lines

Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of the apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of a diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber. Improved heater control circuitry is also disclosed, to provide added or redundant safety measures, or to reduce current leakage from a heater element during pulse width modulation control of the heater. Improvements are also disclosed in the application of negative pressure during a drain phase in peritoneal dialysis therapy, and to control the amount of intraperitoneal fluid accumulation during a therapy. Improvements in efficiency are also disclosed in the movement of fluid into and out of a two-pump cassette and heater bag of a peritoneal dialysis cycler, and in the synchronization of the operation of two or more pumps in a peritoneal dialysis cycler or other fluid handling devices using a multi-pump arrangement.

MODULAR MEDICAL FLUID MANAGEMENT ASSEMBLIES AND ASSOCIATED MACHINES AND METHODS

Medical fluid management assembly includes: a pneumatic manifold including multiple plates forming pneumatic passageways, a pneumatic valve chamber and a pneumatic pump chamber, the valve chamber in pneumatic communication with at least one passageway, the pump chamber in pneumatic communication with at least one passageway; and a fluid manifold including multiple fluid pathways, a fluid valve chamber in selective fluid communication with a fluid pump chamber and at least one fluid pathway, wherein (a) the pneumatic valve chamber and the fluid valve chamber are mated together to compress a membrane and (b) the pneumatic pump chamber and the fluid pump chamber are mated together to compress a membrane, wherein at least one of the pneumatic valve chamber or the pneumatic pump chamber extends from the at least one plate, or the fluid valve chamber or the fluid pump chamber extends from the fluid manifold to aid in compressing the membranes. 1. A medical fluid management assembly comprising:a pneumatic manifold including a plurality of plates sealed together to form a plurality of pneumatic passageways, a pneumatic valve chamber and a pneumatic pump chamber formed by at least one of the plates, the pneumatic valve chamber in pneumatic communication with at least one of the pneumatic passageways, and the pneumatic pump chamber in pneumatic communication with at least one of the pneumatic passageways; anda fluid manifold including a plurality of fluid pathways, a fluid valve chamber and a fluid pump chamber formed by the fluid manifold, the fluid valve chamber in selective fluid communication with the fluid pump chamber and at least one of the fluid pathways, wherein (a) the pneumatic valve chamber and the fluid valve chamber are mated together to compress at least one flexible valve chamber membrane or a valve chamber area of at least one common flexible membrane and (b) the pneumatic pump chamber and the fluid pump chamber are mated together to compress at least one ...

DEVICE AND METHOD FOR OPTIMIZING THE ENERGY CONSUMPTION IN A MEDICAL APPARATUS

A method and a system for optimizing the energy consumption of a medical apparatus comprising a medical instrument, and a further energy consumer are disclosed. The method comprises the following steps: providing treatment plan information, which predetermines a temporal sequence for using the medical instrument, providing interaction information, which predetermines an interaction between the use of the medical instrument and the further energy consumer, providing control information for actuating the further energy consumer on the basis of the treatment plan information and the interaction information. 1. A method for optimizing the energy consumption of a medical facility , comprising a medical device and another energy consumer , where the method comprises the following steps:supplying treatment planning information specifying a chronological sequence for use of the medical device,supplying interaction information specifying an interaction between the use of the medical device and the additional energy consumer,supplying control information for controlling the additional energy consumer on the basis of the treatment planning information and the interaction information.2. The method according to claim 1 , wherein the medical device during operation is a heat source claim 1 , wherein the additional energy consumer is a heater claim 1 , wherein the interaction information comprises heat production associated with operation of the medical device.3. The method for optimizing the power consumption by a medical facility according to claim 1 , wherein the additional energy consumer is a consumer of electric power claim 1 , and wherein the interaction information comprises a consumption of electric power associated with operation of the medical device.4. The method according to claim 3 , wherein the interaction information comprises a time-dependent specification for consumption of electric power claim 3 , in particular a specification for the total consumption of ...

Container for Dialysis Concentrate

A dialysis concentrate container for single-use, comprising a container portion () which can be filled with dialysis concentrate and a connecting portion () connected thereto for connecting the dialysis concentrate container to a dialysis machine, wherein the connecting portion () has laterally spaced fluid connection elements () for connecting to a fluid outlet and a fluid inlet of the dialysis machine, wherein the container body () is formed as a rigid box, wherein the connecting portion () is further arranged at the lower end of the container body, wherein the connecting portion () is formed by a plate body which can be clamped into a connecting block of the dialysis machine, and on the underside of which the fluid connecting elements () are formed, one of which being connected to a fluid inlet of the container body () and the other one being connected to a fluid outlet thereof. 1. A dialysis concentrate container for single-use , comprising a container portion which can be filled with dialysis concentrate and a connecting portion connected thereto for connecting the dialysis concentrate container to a dialysis machine , the connecting portion having laterally spaced fluid connection elements for connecting to a fluid outlet and a fluid inlet of the dialysis machine ,wherein the container portion is configured as a rigid box, in that the connecting portion is further arranged at the lower end of the container portion, and in that the connecting portion is formed by a plate body which can be clamped into a connecting block of the dialysis machine, and on the lower side of which the fluid connection elements are formed, wherein one of the fluid connection elements is connected with a fluid inlet of the container portion and the other one is connected with a fluid outlet thereof.2. The dialysis concentrate container according to claim 1 , wherein the container portion consists of a container body that is open at its top claim 1 , and a lid which can be connected ...

Integrated on-line monitoring and thermostatic heating apparatus for bioartificial liver device

An integrated on-line monitoring and thermostatic heating apparatus for a bioartificial liver device, the apparatus including a blood inlet, a blood pump, an arterial drip chamber, a bioreactor module, a venous drip chamber, and a blood reinfusion port which are connected in sequence. The bioreactor module includes a thermostatic water tank and a bioreactor disposed in the thermostatic water tank. The bioreactor includes a container, and a first partition and a second partition which are disposed in the container. The first partition and the second partition separate the container into three independent parts, that is, a plasma separator, an oxygenator, and a reactor. The plasma separator and the oxygenator are connected through an external connection pipe. The external connection pipe is equipped with a separation pump. The second partition includes a communication hole, and the reactor and the oxygenator are connected through the communication hole.

INDIRECT DRAIN FLUSH SYSTEM FOR DIALYSIS EFFLUENT

An indirect drain flush system incorporating hot water to facilitate the transport of kidney dialysis effluent to wastewater treatment facilities is provided. Heated water is discharged into a waste line through an air gap, and the heated water increases the molecular interchange of fatty substances in the dialysis effluent, decreasing the viscosity of those fatty substances and preventing them from coagulating or crystalizing on pipes and drains. An air admittance valve may prevent negative pressure from building up within the system. 1. An indirect drain flush system for dialysis effluent comprising:a dialysis waste line comprising a spent dialysate input configured for connection to a spent dialysate source, a heated water input configured for receiving heated water from a heated water supply, and a release opening;a water cycler;a heated water air gap positioned between the water cycler and the dialysis waste line; andan air admittance valve;wherein the water cycler is configured to cause heated water to be discharged through the heated water air gap into the heated water input of the dialysis waste line;wherein the spent dialysate input is configured to allow spent dialysate to enter the dialysis waste line and mix with heated water to form mixed effluent;wherein the air admittance valve is configured to regulate pressure in the dialysis waste line; andwherein the release opening is configured to cause mixed effluent to be discharged over at least one drain.2. The indirect drain flush system of further comprising:inspection tubing positioned at a portion of the dialysis waste line.3. The indirect drain flush system of claim 1 , wherein:the air admittance value is positioned on a substantially vertically oriented air admittance pipe.4. The indirect drain flush system of claim 1 , further comprising:an alarm in communication with at least one selected from the group of a flow meter, pressure gage, and combinations thereof, wherein the alarm is configured to ...

Bag Opening System

A system and apparatus for opening and emptying a bag of material includes a base having a pair of opposed sides and a central aperture through which material may flow. The system includes a pair of opposed doors rotatably mounted on a pair of door shafts, the edges of the pair of opposed doors forming an opening and a plurality of piercing blades pivotally mounted to the base on a pivot rod, the blades capable of pivoting to pierce said bag. The system further includes a cutting blade mounted transversely below the opening of the opposed doors, the cutting blade capable of linear motion across the opening.

CONTAINER FOR FLUIDS AND APPARATUS FOR TEMPERATURE CONTROL, E.G. WARMING, OF MEDICAL FLUIDS

A container for warming fluids, the container comprising an inlet port, an outlet port, and a fluid conduit configured for putting the inlet port in fluid communication with the outlet port and comprising one or more deflection sections. The fluid conduit has a non-constant maximum width in a direction of fluid flow through the fluid conduit. At least one of the one or more deflection sections further comprises an entry section and an exit section, each respective exit section being arranged downstream, in the direction of fluid flow, from each respective entry section. The maximum width of the fluid conduit decreases along the direction of fluid flow through the entry section over a first distance and the maximum width of the fluid conduit increases along the direction of fluid flow through the exit section over a second distance, the first distance and the second distance being different from one another. An apparatus for warming medical fluids including the container and an extracorporeal blood circuit including the container are also provided. An extracorporeal blood treatment apparatus including the apparatus for warming medical fluids and/or the extracorporeal blood circuit is also provided. 117-. (canceled)18. A container for fluids , wherein the container comprises a flexible bag with at least a first and a second film sealed to one another , the container comprising:an inlet port;an outlet port; anda fluid conduit to put the inlet port in fluid communication with the outlet port and comprising one or more deflection sections,wherein the fluid conduit has a non-constant maximum width in a direction of fluid flow through the fluid conduit,wherein at least one of the one or more deflection sections further comprises an entry section and an exit section, each respective exit section being arranged downstream, in the direction of fluid flow, from each respective entry section, andwherein the maximum width of the fluid conduit decreases along the direction of ...

Filling device of a fluid system

Disclosed is a filling device of a fluid conducting system of an extracorporeal blood treatment device that includes a spike for connecting to the single fluid connector of a medical fluid container and a manually operable fluid blocking mechanism arranged directly downstream of the spike that fluidly connects with the spike while the filling device is in operation. The fluid blocking mechanism has at least one fluid outlet connector that is adapted so that a line section or hose of the fluid conducting system such as the arterial line section of a blood purification device can be connected to it in a detachable manner while the filling device is in operation.

METHOD OF MANUFACTURING A CONCENTRATE

The present invention relates to a method of providing at least one concentrate of at least one dissolved substance for producing at least one dialysis solution, with the method comprising the following steps: providing at least one container containing at least one solid to be dissolved; supplying water into the container for dissolving the solid; draining the concentrate of the dissolved substance from the container and topping up with water; measuring the concentration of the dissolved substance or of a parameter correlated with the concentration; and temporary or permanent suppression of the topping up of water into the container when the measured concentration value of the dissolved substance falls below a first limit value or the value of the parameter falls below or exceeds a first limit value or when the change in the concentration value of the dissolved substance or of the value of the parameter exceeds a first limit value. 1. A method of providing at least one concentrate of at least one dissolved substance for producing at least one dialysis solution , characterized in that the method comprises the following steps: providing at least one container containing at least one solid to be dissolved; supplying water into the container for dissolving the solid; draining the concentrate of the dissolved substance from the container and topping up with water; measuring the concentration of the dissolved substance or of a parameter correlated with this concentration; and temporary or permanent suppression of the topping up of water into the container when the measured concentration value of the dissolved substance falls below a first limit value or the value of the parameter falls below or exceeds a first limit value or when the change in the concentration value of the dissolved substance or of the value of the parameter exceeds a first limit value.2. A method in accordance with claim 1 , characterized in that the concentration of the dissolved substance or the ...

DIALYSIS SYSTEM

A dialysis system includes a filtration system capable of filtering a water stream, a water purification system capable of purifying said water stream in a non-batch process, a mixing system capable of producing a stream of dialysate from mixing one or more dialysate components with the water stream in a non-batch process, and a dialyzer system. The dialyzer may be a microfluidic dialyzer capable of being fluidly coupled to the stream of dialysate and a blood stream. 1. A dialysis system , comprising: a fluid pathway having a water inlet and a water outlet, the fluid pathway further comprising', 'a first region where water flows in a first direction at a first temperature;', 'a heater region downstream of the first region, the water flowing into the heater region at the first temperature and the heater region comprising at least one heater that transfers heat into the water flowing through the heater region to increase the temperature to a second temperature greater than the first temperature; and', 'a second region downstream of the heater region where water flows in a second direction at a temperature greater than the first temperature, wherein water flowing in the second region thermally communicates with water flowing in the first region such that heat transfers from water flowing in the second region to water flowing in the first region resulting in a temperature reduction in the water as it flows through the second region, wherein water flows out of the fluid pathway through the water outlet at a temperature less than the second temperature;, 'a water purification system comprising a microfluidic channel, flow field, or both, the water purification system capable of processing a household water stream in a non-batch process to produce a pasteurized water stream, the water purification system comprising a heat exchange system comprising'}a dialysate preparation system capable of mixing the pasteurized water stream with dialysate components to produce a ...

Degassing module for a controlled compliant flow path

A degassing module for removal of air and other gases during operation of a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The degassing module has a flow-through first chamber that has a hydrophobic vent membrane that has an exterior and interior side forming a portion of the flow-through chamber. The hydrophobic vent membrane is positioned at a higher elevation on the flow-through chamber than a fluid outlet. Fluid flows through the flow-through chamber in a downward direction relative to the hydrophobic vent membrane. A flow-through chamber has a cross sectional area configured to provide for a downward flow velocity of the fluid to be less than the upward rise velocity of a smallest bubble to be removed from the fluid.

Apparatus relating to hemodialysis, hemodiafiltration, hemofiltration or peritoneal dialysis having function for rise temperature

Disclosed is an apparatus having a heating function for hemodialysis, hemodiafiltration, hemofiltration or peritoneal dialysis, wherein the apparatus includes at least one of pipe for transferring at least one fluid of blood and dialsate, and a heating unit for heating at least one fluid of blood and dialsate, wherein the fluids to be heated by the heating unit are substances to be injected into human body; and the heating unit is arranged for measuring flow rates of the fluids to be heated, and injecting temperatures related with the flow rate to heat the fluids to be heated. The heating unit comprises: flow passages through which the fluids to be heated are flowed; a heater formed as a part of the flow passages, for generating heat; and a cover means including a first connection portion through which the fluids enter the flow passages, and a second connection portion through which the fluids come out from the flow passages. Present invention provides one effect in that blood having the same or nearly same temperature as that of human body can be injected into human body to prevent side effects caused by the dialysis and another effect in that blood can be heated effectively because the shapes of flow passages around the heater is deformed in improved manner.