25-02-2021 дата публикации
Номер: US20210052635A1
Embodiments presented herein relate to various polymers. Some of the polymer embodiments are heparin binding polymers. Some embodiments of the heparin binding polymers can be employed to bind to heparin for methods such as separating, purifying, removing, and/or isolating heparin and heparin like molecules. 1 {'sub': '1-18', 'sup': '1', 'claim-text': {'sup': '1', 'wherein each Ris independently selected from a polymer segment having monomer units of Formula (III), 'a core unit, wherein the core unit comprises a Calkyl substituted with three or more of —OR,'}, 'administering a heparin binding polymer to the subject, wherein the heparin binding polymer comprises. A method of counteracting heparin in a subject, the method comprising: wherein n is an integer from 1 to 10,000,', {'sup': 2', '1, 'wherein each Ris independently selected from a hydrogen, carbon, a cationic moiety, R, and a polymer segment of Formula (IV)]}}} [{'sup': '3', 'wherein each Ris independently selected from an oxygen cationic moiety, a hydroxyl, and a polymer segment of Formula (IV),'}, 'wherein m is an integer from 1 to 10,000,', {'sup': '4', 'sub': '1-6', 'wherein each Ris independently selected from a Calkoxy, and'}]}}}wherein the heparin binding polymer comprises 1 to 300 cationic moieties. This application is a continuation under 35 U.S.C. § 120 of U.S. application Ser. No. 15/887,561, filed Feb. 2, 2018, which is a continuation under 35 U.S.C. § 120 of U.S. application Ser. No. 14/629,408, filed on Feb. 23, 2015, now U.S. Pat. No. 10,111,902, which is a continuation under 35 U.S.C. § 120 of U.S. application Ser. No. 14/098,184, filed on Dec. 5, 2013, now U.S. Pat. No. 9,095,666, which is a divisional under 35 U.S.C. § 121 of U.S. application Ser. No. 13/458,899, filed on Apr. 27, 2012, now U.S. Pat. No. 8,637,008, which is a continuation under 35 U.S.C. § 120 of U.S. application Ser. No. 13/504,841, filed on Apr. 27, 2012, now U.S. Pat. No. 8,519,189, which was the U.S. National Phase entry ...
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