Inteligent disposable devices for wound therapy and treatment

System and method for treating a wound using ultrasonic debridement

APPARATUS FOR DIRECTLY DISPLACING THE PARTITION BETWEEN THE MIDDLE EAR AND INNER EAR AT AN INFRASONIC FREQUENCY

Injection system for delivering multiple fluids within the anatomy

Devices and systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, a joint or intra-articular space, include a handpiece assembly having a needle extending from its distal end, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medicaments, formulations and/or other fluids or materials contained within vials that are secured to a cassette or other portion of the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

Nozzle for ultrasound wound treatment

Surgical cassette apparatus

H:\kmih\Intrwovn\NRPortbl\DCC\KMH83320_I.docx-23/02/2015 A method for selectively venting and aspirating fluid to and from a handpiece (110) employed in an ocular surgical procedure. The method includes providing a first pumping operation and a second pumping operation, and selecting operation between the first pumping operation and the second pumping operation using a flow selector valve (202). The first pumping operation controls fluid flow to and from an eye using a first pump fluidly connecting the flow selector valve (202) to a first fluid pathway via a first port in the flow selector valve and the second pumping operation controls fluid flow to and from the eye using a second pump fluidly connected to the flow selector valve via a second fluid pathway connected to a second port in the flow selector valve (202). Fig. 2 ...

LIPOSUCTION DEVICES AND METHODS AND SURROUNDING ASPIRATION SYSTEMS AND METHODS

Liposuction devices and methods and surrounding aspiration systems and methods that reduce the chances of burning and necrosis. The devices include an evacuation tube surrounding an ultrasonic probe, including the distal end thereof to define a liquefaction and/or rupture chamber. The evacuation tube has one or more openings in the distal end through which tissue such as fatty tissue may enter for rupture/liquefaction therein. Containing the ultrasonic probe within the evacuation tube avoids any possible contact with surrounding tissue other than tissue that gets drawn into the liquefaction and/or rupture chamber. The size of the liquefaction and/or rupture chamber may be variable by adjustment of the axial position of the evacuation tube relative to the ultrasonic probe, or by selection of evacuation tubes of the desired length. Various embodiments are disclosed.

WOUND TREATING APPARATUS AND METHOD

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus. © KIPO & WIPO 2008 ...

NOZZLE FOR ULTRASOUND FOR WOUND TREATMENT

A nozzle for ultrasound wound treatment comprising a main body with proximal and distal ends, a reservoir and valve. The proximal end of the nozzle being removably attached to an ultrasound transducer. The distal end of the nozzle being marginally close and coaxial to the free distal end of the ultrasound transducer. The body of the nozzle connected with liquid reservoir, which holds the wound treatment solution and delviers same to the free end of ultrasound tip directly or through a tube. The nozzle is provided with valve for controlling flow rate of wound treatment solution. The nozzle can mix different liquids or a liquid with a gas and deliver same to the wound surface. The nozzle can also be provided with trigger system for one hand use. The present invention is a device, using ultrasonic waves to create, direct and deliver liquid treatment spray to a wound surface.

ULTRASONIC METHOD AND DEVICE FOR WOUND TREATMENT

The method and device of the present invention for ultrasound wound treatment includes a transducer to produce ultrasonic waves. The ultrasonic transducer has tip with the distal end (radiation surface). A liquid is directed to the radiation surface through central orifice or separate tube wherein an directed atomized particle spray of the liquid is created upon contact of the liquid with the radiation surface. The spray directed to the wound from at least 0,1 inches transmits ultrasound waves through particles and has an irrigation, mechanical cleansing, liquid energizing and bactericide effect.

System for reducing local discomfort

A device for targeted delivery of a substance to an airway may include a conduit and at least two applicators. The conduit may include a proximal end and a bifurcated distal portion having two distal ends. Each applicator may be coupled with one of the distal ends of the conduit and may be configured to direct the substance out of the applicator toward one of two sides of an airway. A method for targeted delivery of a substance to an airway may involve advancing a substance delivery device into the airway, contacting two sides of the airway with at least two applicators of the substance delivery device, such that each applicator contacts the airway near a glossopharyngeal nerve and/or a superior laryngeal nerve on each of the two sides of the airway, and delivering the substance through the applicators to contact the airway along the two sides.

Apparatus to facilitate removal of cataracts of from the eyes

This apparatus is a device for removal of cataracts from the eyes of patient. The apparatus includes a hand piece, with an irrigation water line, a vacuum line and a power line provided therein, are all connected with the hand piece. Within the hand piece the vacuum line is attached to a tube, identified as the horn, concentric with the outer shell of the hand piece. Through a hooks and slider joint, bayonet type or threaded joint in the front end, the horn connects with a surgical needle. At the front end of the irrigation tube it discharges water into a chamber, which irrigation water passes between the needle and an outer sleeve and into the anterior chamber of the eye. Ultrasonic waves transmitted to the horn are conveyed to the tip of the needle where the axial vibrations of the tip may be used to comminute cataract material.

TARGETED DELIVERY OF AEROSOLS OF MAGNETIZED ACTIVE AGENTS

The invention provides compositions, kits and methods for depositing a composition comprising a plurality of magnetic particles, to a target site of a subject by delivering the composition via controlled inhalation to a region of the subject's respiratory tract and applying a magnetic field to a target site within the region of the subject's respiratory tract to capture the particles in said target site.

Systems and methods to prevent catheter occlusion

A system to detect occlusion of an intravenous catheter may include a housing, which may include a distal end configured to couple to a proximal end of a catheter adapter and an inner lumen forming a fluid pathway. The system may also include one or more transmitters, which may be disposed within the housing. The transmitters may be configured to transmit first energy waves along a length of an intravenous catheter at a first frequency, and a portion of the first energy waves that are reflected back from the catheter may be detected by the system. Based on the portion of the first energy waves that are reflected back from the catheter, the transmitters may transmit second energy waves along the length of the catheter at a second frequency, which may be greater than the first frequency and configured to reduce formation of blood clots within the catheter.

EXTRACORPOREAL BLOOD CLEANING

Tissue treatment device

FAT SUCTION APPARATUSES AND SURROUNDINGS OF SUCTION SYSTEMS

DEVICE FOR THE DISTANCE OF PROTEIN-BOUND SUBSTANCES

Ultrasound system and method for revascularization and drug delivery

Systems and methods for a wearable device for treating a health condition using ultrasound stimulation

In some aspects, a device wearable by or attached to or implanted within a person includes a sensor configured to detect an electroencephalogram (EEC) signal from the brain of the person and a transducer configured to apply to the brain a low power, substantially non-destructive ultrasound signal.

TOPICAL APPLICATION OF MEDICATION BY ULTRASOUND WITH COUPLING AGENT

SYSTEMS AND METHODS FOR A WEARABLE DEVICE FOR SUBSTANTIALLY NON-DESTRUCTIVE ACOUSTIC STIMULATION

In some aspects, a device wearable by a person includes a sensor configured to detect a signal from the brain of the person and a transducer configured to apply to the brain an ultrasound signal. The ultrasound signal has a low power density and is substantially non-destructive with respect to tissue when applied to the brain.

A METHOD FOR ASSESSING A PATIENT'S FLUID STATUS AND/OR SENSITIVITY TO FLUID REMOVAL, CONTROLLER, AND DEVICES

The present invention relates to a method for assessing a patient's sensitivity to fluid removal from his vascular system or to fluid replacement or addition regarding to his hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfils at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage means, a computer program product, and a computer program.

METHOD FOR EVALUATING LIQUID STNOGO STATUS OF A PATIENT AND/OR SENSITIVITY TO REMOVAL OF LIQUID STI, CONTROLLER AND DEVICE

SYSTEM FOR TREATING A WOUND USING ULTRASONIC DEBRIDEMENT

상처 치료 시스템은 분산 매니폴드, 감압원, 유체 전달원 및 초음파 에너지 변환기를 포함한다. 감압 및 유체 전달은 상기 분산 매니폴드를 통해 상처에 인가될 수 있다. 초음파 에너지 변환기는 상기 상처에 초음파 에너지를 전달하여 상처의 괴사 조직을 제거하도록 구성된다. 초음파 에너지 변환기는 압전 변환기이거나 표면 탄성파 소자일 수 있다. 초음파 에너지 변환기는 상처에 직접 초음파 에너지를 전달하기 위해 상기 분산 매니폴드에 인접하여 배치되거나, 상기 분산 매니폴드와 상처 사이에 위치하는 음향-전도성 멤브레인에 연결될 수 있다. Wound care systems include dispersing manifolds, decompression sources, fluid delivery sources, and ultrasound energy transducers. Decompression and fluid delivery can be applied to the wound through the dispersion manifold. An ultrasonic energy converter is configured to deliver ultrasonic energy to the wound to remove necrotic tissue of the wound. The ultrasonic energy transducer may be a piezoelectric transducer or a surface acoustic wave element. Ultrasonic energy transducers may be disposed adjacent the dispersion manifold to deliver ultrasonic energy directly to the wound, or may be connected to an acoustic-conductive membrane located between the dispersion manifold and the wound. 상처 치료 시스템, 드레싱, 초음파 에너지, 분산 매니폴드, 감압원 Wound Care System, Dressing, Ultrasound Energy, Dispersion Manifold, Decompression Source

A METHOD FOR ASSESSING A PATIENT'S FLUID STATUS AND/OR SENSITIVITY TO FLUID REMOVAL, CONTROLLER, AND DEVICES

Ultrasound equipment, systems and application methods

An ultrasound emission device (10) includes, within a case (12) having a watertight structure, an ultrasonic transducer (20), a power source (16), and a control unit (17). The ultrasonic transducer (20) is attached to the inside of the case (12) via an acoustic matching layer (22). An acoustic scattering layer (24) is provided on the outside of the case (12). The acoustic scattering layer (24) is formed from a material for which the acoustic impedance difference with water is large. One example of the acoustic scattering layer (24) is a wire net. High-strength ultrasonic waves (19) generated by the ultrasonic transducer (20) are scattered by the acoustic scattering layer (24) and emitted, as low-strength ultrasonic waves (21), to a wide area of a human body. The ultrasound emission device (10) can be floated on water inside a water tank (52), or can be used in the water inside the water tank (52). With the present invention, ultrasound stimulation can be applied to the bones of nearly the ...

DRUG DELIVERY DEVICE

The present disclosure presents systems, devices and methods for injection of drugs, substances and/or chemicals to a patient and for improving their effectiveness once they are injected are disclosed. Additional treatment can be applied to a tissue region on the patient into which a drug (e.g., insulin) is injected, to expose the tissue region to various forms of energy or a substance to improve the drug's pharmacokinetic and/or pharmacodynamic profile.

ULTRASONIC IMPLANT, SYSTEMS AND METHODS RELATED TO DIVERTING MATERIAL IN BLOOD FLOW AWAY FROM THE HEAD

A system for directing ultrasonic energy through blood flow in the aorta (20) of a patient proximate the origins of the great vessels (12, 14, 16) to the head of the patient to divert material in the blood flow from the origins of the great vessels (12, 14, 16). The system comprises a first device (62) configured for introduction into the cardiovascular system of the patient and positioning proximate the origins of the great vessels (12, 14, 16) to the head of the patient, and at least one ultrasonic energy emitter (60) carried by said first device.

SUCTION EVACUATION DEVICE

A method for removing a stone from a patient comprising the steps of: providing a suction evacuation assembly which includes a sheath and one or more side arms; inserting and positioning a distal end of the sheath into a lumen or cavity of a patient's body containing a stones; connecting a tube to one of the side arms and to a collection bottle; connecting another tube to the collection bottle and a negative pressure system; visualizing the stone or foreign body using a scope inserted through the assembly; activating the negative pressure system in order to remove the stone from the cavity if the diameter of the stone is narrower than an inside diameter of the sheath and the side arm, or performing a lithotripsy on the stone to create fragments with a decreased diameter which allow the passage through the assembly; and collecting the stone in the collection bottle.

Device for removing protein-based substances

The present invention relates to a means of dialysis for removing protein-bound substances from a biological fluid, especially blood or blood plasma, which contains at least one means for solubilizing protein-binding substances to be removed into the biological fluid and/or dialysis fluid, and to a process for removing protein-bound substances from a biological fluid.

SYSTEMS AND METHODS TO PREVENT CATHETER OCCLUSION

A system to detect occlusion of an intravenous catheter may include a housing, which may include a distal end configured to couple to a proximal end of a catheter adapter and an inner lumen forming a fluid pathway. The system may also include one or more transmitters, which may be disposed within the housing. The transmitters may be configured to transmit first energy waves along a length of an intravenous catheter at a first frequency, and a portion of the first energy waves that are reflected back from the catheter may be detected by the system. Based on the portion of the first energy waves that are reflected back from the catheter, the transmitters may transmit second energy waves along the length of the catheter at a second frequency, which may be greater than the first frequency and configured to reduce formation of blood clots within the catheter. 1. A method of preventing occlusion of an intravenous catheter , comprising:transmitting, via a transmitter, first energy waves along a length of an intravenous catheter of a catheter adapter at a first frequency;converting, via a transducer, a portion of the first energy waves that are reflected back from the intravenous catheter to a corresponding electrical signal;receiving the electrical signal at a processor coupled to the transducer;comparing the electrical signal to a baseline electrical signal to determine a difference between the electrical signal and the baseline electrical signal; andin response to the difference between the electrical signal and the baseline electrical signal being below a threshold value, transmitting, via the transmitter or another transmitter, second energy waves along the length of the intravenous catheter of the catheter adapter at a second frequency greater than the first frequency, wherein the second energy waves reduce formation of blood clots within the intravenous catheter.2. The method of claim 1 , wherein the second frequency is between 300 MHz and 300 GHz.3. The method of ...

Methods, systems, and kits for lung volume reduction

Lung volume reduction is performed in a minimally invasive manner by isolating a lung tissue segment, optionally reducing gas flow obstructions within the segment, and aspirating the segment to cause the segment to at least partially collapse. Further optionally, external pressure may be applied on the segment to assist in complete collapse. Reduction of gas flow obstructions may be achieved in a variety of ways, including over inflation of the lung, introduction of mucolytic or dilation agents, application of vibrational energy, induction of absorption atelectasis, or the like. Optionally, diagnostic procedures on the isolated lung segment may be performed, typically using the same isolation/access catheter.

DEVICE AND METHOD TO COOL THE BRAIN AND TO DIAGNOSE AND TREAT GLIOBLASTOMA

СИСТЕМА И СПОСОБ ОБРАБОТКИ РАН С ИСПОЛЬЗОВАНИЕМ УЛЬТРАЗВУКОВОЙ ХИРУРГИЧЕСКОЙ ОЧИСТКИ

FIELD: medicine. SUBSTANCE: group of inventions refers to medicine, namely to wound treatment methods and apparatuses by means of combination of ultrasonic wound purification and low pressure therapy. The wound treatment system comprises a supply manifold, a low pressure source, a liquid source, an ultrasonic transducer and an adjoining protective film for closing of the supply manifold and the ultrasonic transducer. The second version of the treatment system additionally involves a sound-conducting membrane adjoining the manifold. The wound treatment method provides using the system with the supply manifold accommodating a number of flow passages and adjoining a wound area. For the first version, supplied ultrasonic energy power is 1 Wt/cm 2 for 10 minutes a day. For the second version, liquid from the liquid source is supplied to the wound during first time, while ultrasonic energy is supplied during second time, and low pressure - during third time. For the third version, low pressure and ultrasonic energy are supplied to the wound simultaneously, and low pressure is maintained by means of the protective film placed over the supply manifold. For the fourth version, liquid is preliminary supplied in the wound, then ultrasonic energy; then liquid and separated tissue are removed by low pressure. The wound treatment system can be presented in the form of a wound bandage. EFFECT: use of the group of inventions allows providing higher clinical effectiveness. 26 cl, 2 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 428 209 (13) C2 (51) МПК A61M A61M A61F A61M A61N 1/00 (2006.01) 27/00 (2006.01) 13/00 (2006.01) 35/00 (2006.01) 7/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ, ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2008128549/14, 23.01.2007 (24) Дата начала отсчета срока действия патента: 23.01.2007 (73) Патентообладатель(и): КейСиАй Лайсензинг, Инк. (US) R U Приоритет(ы): (30) Конвенционный приоритет: 23.01.2006 US 60/ ...

СИСТЕМА И СПОСОБ УХОДА ЗА КОЖЕЙ

Группа изобретений относится к медицинской технике. Представлены система и способ для обработки слоя эпителиальной ткани. Система содержит резервуар для содержания некоторого количества текучей среды, выполненный с предоставлением возможности среде, когда она содержится в резервуаре, соприкасаться с поверхностью слоя эпителиальной ткани, источник света для генерирования лазерного луча в течение по меньшей мере заданной длительности импульса, а также оптическую систему для фокусировки лазерного луча в фокальное пятно и для расположения фокального пятна в целевом положении. Целевое положение фокального пятна находится в пределах резервуара и в пределах среды и на расстоянии менее чем 3 мм от поверхности слоя эпителиальной ткани, когда она содержится в резервуаре, и размер фокального пятна и мощность генерируемого лазерного луча таковы, что в фокальном пятне лазерный луч имеет плотность мощности, которая превышает характеристическое пороговое значение для этой среды, выше которого при заданной длительности импульса происходит событие лазерно-индуцированного оптического пробоя в среде. Группа изобретений позволяет получить более отчетливый эффект при воздействии на ткань. 2 н. и 13 з.п. ф-лы, 5 ил. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 635 477 C2 (51) МПК A61M 37/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2014144665, 25.06.2013 (24) Дата начала отсчета срока действия патента: 25.06.2013 (72) Автор(ы): БРАТХЕНИА Алиаксандр (NL), ВЕРХАГЕН Рико (NL) (73) Патентообладатель(и): КОНИНКЛЕЙКЕ ФИЛИПС Н.В. (NL) Дата регистрации: (56) Список документов, цитированных в отчете о поиске: DE 10144102 A1, 20.03.2003. US Приоритет(ы): (30) Конвенционный приоритет: 05.07.2012 US 61/668,103 (45) Опубликовано: 13.11.2017 Бюл. № 32 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 05.11.2014 (86) Заявка PCT: IB 2013/055196 (25.06.2013) (87) Публикация заявки PCT: 2 6 3 5 4 7 7 (43) Дата публикации ...

УСТРОЙСТВО ДЛЯ ДОСТАВКИ ЛЕКАРСТВЕННОГО СРЕДСТВА

FIELD: medicine. SUBSTANCE: invention refers to medical equipment, namely to systems for drug delivery to a patient, particularly to a system for subcutaneous drug delivery, and use of one or more therapeutic sources for providing more effective introduction of drugs. The system for therapeutic fluid delivering to the patient at the injection point comprises a fluid injection device and a therapeutic element. The fluid injection device comprises a case. The case accommodates an injector for therapeutic liquid introduction at the injection point and a therapeutic fluid reservoir. The therapeutic element is attached to the fluid injection device and is applicable for the therapy at the injection point and/or near it. The therapeutic element is further designed for improving the pharmacokinetic and/or pharmacodynamic properties of the therapeutic fluid, either before or during and/or after the therapeutic fluid injection to the patient. EFFECT: invention provides an efficient and rapid drug injection and absorption in the patient's systemic circulation, and particularly increases the efficacy of blood insulin to maintain normal blood glucose levels and prevent or reduce hyperglycemia and hypoglycemia. 29 cl, 13 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 481 128 (13) C2 (51) МПК A61M A61M 5/20 5/44 (2006.01) (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2009135627/14, 19.03.2008 (24) Дата начала отсчета срока действия патента: 19.03.2008 (73) Патентообладатель(и): Инсьюлин Медикал Лтд. (IL) 2 4 8 1 1 2 8 (43) Дата публикации заявки: 27.04.2011 Бюл. № 12 2 4 8 1 1 2 8 R U (56) Список документов, цитированных в отчете о поиске: WO 00/32259 A, 08.06.2000. SU 211733 A1, 19.02.1968. RU 2147893 C1, 27.04.2000. WO 03/086534 A, 23.10.2003. WO 00/23132 A, 27.04.2000. FR 2795629 A, 05.01.2001. US 2005/015055 A1, 20.01.2005. (85) Дата начала рассмотрения заявки PCT на национальной фазе: 19.10.2009 (86) Заявка ...

УСТРОЙСТВО ДЛЯ ДОСТАВКИ ЛЕКАРСТВЕННОГО СРЕДСТВА

1. Устройство для доставки терапевтической жидкости пациенту на участке инъекции, содержащее:кожух, имеющий первый резервуар для содержания терапевтической жидкости и второй резервуар для содержания терапевтического вещества;инъектор для введения терапевтической жидкости на участке инъекции;терапевтический элемент, выполненный с возможностью введения терапевтического вещества на участке инъекции незадолго до, во время и/или после инъекции терапевтической жидкости;причем введенное терапевтическое вещество предназначено для улучшения по меньшей мере одного фармакокинетического и/или фармакодинамического свойства введенной терапевтической жидкости.2. Устройство по п.1, в котором инъектор содержит шприц, или безыгольный шприц, или ручку-инъектор, или любую комбинацию указанных элементов.3. Устройство по п.1, в котором второй резервуар и первый резервуар перед инъекцией расположены в одном кожухе.4. Устройство по п.1, в котором второй резервуар является неотъемлемой частью кожуха.5. Устройство по п.1, в котором второй резервуар выполнен с возможностью съема с кожуха, а также с возможностью выполнения смены, замены и/или добавления к кожуху.6. Устройство по п.1, в котором указанная терапевтическая жидкость содержит инсулин, или инсулиновый аналог, или инсулиновый имитатор, или любую комбинацию указанных веществ.7. Устройство по п.6, дополнительно содержащее датчик для обнаружения и измерения уровня глюкозы в теле пациента.8. Устройство по п.7, в котором терапевтический элемент выполнен с возможностью введения дозировки терапевтического вещества, основанной на измеренном уровне глюкозы в теле пациента.9. Устрой� РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК A61M 5/20 (13) 2013 102 423 A (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2013102423/14, 14.01.2013 (71) Заявитель(и): Инсьюлин Медикал Лтд. (IL) Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): ПЕСАЧ Бенни (IL), БИТТОН Габриэль (IL), НАГАР Рон (IL), ...

FETTABSAUGVORRICHTUNGEN UND UMGEBENDE ABSAUGSYSTEME

Tissue treatment device

Methods, systems, and kits for lung volume reduction

VENTILATION MACHINE AND METHOD OF VENTILATING A PATIENT

A ventilation machine (1) comprises a conduit interface (12) configured to be connected to a respiratory system of a human or animal patient (5), an air flow generator (11) configured to deliver air through the conduit interface (12) into the respiratory system of the patient (5), a processing unit (3) in communication with the air flow generator (11) and configured to control the airflow generator to deliver air into the respiratory system of the patient (5) according to a breathing scheme, and an induction device (2) for activating a diaphragm of the patient (5). The induction device (2) is in communication with the processing unit (3). The processing unit (3) is configured to control the induction device (2) to activate the diaphragm in coordination with the breathing scheme.

CATAMENIAL FLUID REMOVAL

The invention provides a device for aspirating uterine fluid of a woman in her period, enabling her, without using tampons, pads or synthetic hormones, to be free of menstrual flow for six or more hours and to be involved in even the most demanding activities entirely undisturbed.

WOUND TREATING APPARATUS AND METHOD

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus.

LIPOSUCTION DEVICES AND METHODS AND SURROUNDING ASPIRATION SYSTEMS AND METHODS

Liposuction devices and methods and surrounding aspiration systems and methods that reduce the chances of burning and necrosis. The devices include an evacuation tube surrounding an ultrasonic probe, including the distal end thereof to define a liquefaction and/or rupture chamber. The evacuation tube has one or more openings in the distal end through which tissue such as fatty tissue may enter for rupture/liquefaction therein. Containing the ultrasonic probe within the evacuation tube avoids any possible contact with surrounding tissue other than tissue that gets drawn into the liquefaction and/or rupture chamber. The size of the liquefaction and/or rupture chamber may be variable by adjustment of the axial position of the evacuation tube relative to the ultrasonic probe, or by selection of evacuation tubes of the desired length. Various embodiments are disclosed.

Method and device for drug delivery

The invention provides a method and a device for a delivery of a chemical substance to the body of the patient. The device includes an infusion catheter configured to be inserted into a tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.

máquina de ventilação e método de ventilação de um paciente

COMPOSITION, DEVICE, AND METHOD FOR SUBCUTANEOUS FAT REMOVAL

A composition of matter, device and method for dissolving fat associated, with or near the skin. The composition is directed to perfluorocarbon compositions, the devices incorporate perfluorocarbons for topical application to the skin, and methods involve either subdermal injection or topical application of perfluorocarbon compositions.

APPARATUS FOR DIRECTLY DISPLACING THE PARTITION BETWEEN THE MIDDLE EAR AND INNER EAR AT AN INFRASONIC FREQUENCY

An apparatus for displacing a partition between a middle ear and an inner ear to treat the symptoms of Meniere's disease or endolymphatic hydrops comprises a treatment member for being disposed in the middle ear adjacent the partition and a driver for driving the treatment member to move against the partition to thereby displace the partition at an infrasonic frequency to influence fluid distribution in the inner ear. A method for treating an ear comprises the steps of disposing a treatment device within the middle ear and moving at least a portion of the treatment device against the partition at an infrasonic frequency to displace the partition to influence fluid in the inner ear.

Injection instrument with ultrasonic oscillating element

A medicinal injection instrument for injecting a medicinal medium into a living body includes a tubular arrangement for conducting a medicinal medium to an injection site, the tubular arrangement having a distal end. An ultrasonic oscillator device has an ultrasonic oscillator element juxtaposed to the distal end such that when the instrument is inserted into a living body with the distal end disposed juxtaposed to the injection site, the ultrasonic oscillator element is also disposed juxtaposed to the injection site to thereby enhance diffusion and penetration of the medicinal medium into the body tissue.

Selective removal of age-modified cells for treatment of atherosclerosis

A method of treating atherosclerosis comprises removing AGE-modified cells from a patient. The AGE-modified cells include erythrocytes, intima cells, endothelial cells, smooth muscle cells, macrophages, and foam cells. A variety of techniques, such as ultrasound and binding with an anti-AGE antibody, may be used to identify and remove the AGE-modified cells.

HANDPIECE FOR THE PHACOEMULSIFICATION OF AN EYE LENS

METHOD AND APPARATUS FOR TREATMENT OF INTRACRANIAL HEMORRHAGES

Directed fluidics

Methods and systems for administering directed fluidics during a medical procedure for removing an object are disclosed. A method includes inserting first and second medical instruments into a treatment site, providing irrigation and aspiration of the treatment site through the first and second medical instruments, determining a characteristic of one of the irrigation and the aspiration, and selecting a characteristic of the other of the irrigation and aspiration based on the determined characteristic.

Surgical cassette apparatus

H:\kmih\Intrwovn\NRPortbl\DCC\KMH83320_I.docx-23/02/2015 A method for selectively venting and aspirating fluid to and from a handpiece (110) employed in an ocular surgical procedure. The method includes providing a first pumping operation and a second pumping operation, and selecting operation between the first pumping operation and the second pumping operation using a flow selector valve (202). The first pumping operation controls fluid flow to and from an eye using a first pump fluidly connecting the flow selector valve (202) to a first fluid pathway via a first port in the flow selector valve and the second pumping operation controls fluid flow to and from the eye using a second pump fluidly connected to the flow selector valve via a second fluid pathway connected to a second port in the flow selector valve (202). Fig. 2 ...

ULTRASOUND SYSTEM AND METHOD FOR REVASCULARIZATION AND DRUG DELIVERY

A method and device for improving blood circulation to an area of interest within a patient's heart is described. The method comprises inserting a guidable elongated flexible ultrasound device into a patient's vasculature, applying ultrasonic energy to an area in need of improved circulation, and injecting materials such as angiogenic materials or contrasting agents into the area of interest. The device, suitable for performing the method, comprises an elongated tubular body, a distal head of the elongated tubular body for introducing ultrasonic energy to an area of interest, and a needle to deliver materials to an area of interest.

METHOD AND DEVICE FOR DRUG DELIVERY

Published without an ...

SYSTEMS AND METHODS TO PREVENT CATHETER OCCLUSION

A method and a system (100) to prevent occlusion of an intravenous catheter. A housing is provided, which includes a distal end configured to couple to a proximal end of a catheter adapter and an inner lumen forming a fluid pathway. The system (100) includes one or more transmitters (102), which are disposed within the housing. The transmitters (102) are configured to transmit first energy waves along a length of an intravenous catheter at a first frequency, and a portion of the first energy waves that are reflected back from the catheter is detected by the system (100). Based on the portion of the first energy waves that are reflected back from the catheter, the transmitters (102) transmit second energy waves along the length of the catheter at a second frequency, which is greater than the first frequency and configured to reduce formation of blood clots within the catheter.

SYSTEMS AND METHODS FOR A WEARABLE DEVICE FOR ACOUSTIC STIMULATION

In some aspects, a device wearable by or attached to or implanted within a person includes a sensor configured to detect a signal from the brain of the person and a transducer configured to apply to the brain an acoustic signal. The sensor and the transducer are disposed on the head of the person in a non-invasive manner. The device includes a processor in communication with the sensor and the transducer.

APPARATUS FOR PROVIDING LIGHT THERAPY

Methods and apparatuses for providing therapy, including light therapy, to a user positioned within an enclosure are described herein. A method includes generating and selecting therapy settings based on user information and positioning the user within an enclosure having a plurality of light sources. The enclosure is configured to focus light on the user at a location within the enclosure according to selected settings. Post-therapy user information is provided to generate a report regarding the user and may include the user's measured physical attributes, measured spectrum values, reported information, or survey information. Aromatherapy, audio therapy, or air therapy may be additionally provided. An apparatus includes an enclosure with a control system configured to perform a therapy method. An enclosure may be have the shape of an octagon or another shape. A computer readable non-transitory storage media includes instructions for providing therapy to a user positioned within the enclosure ...

A METHOD FOR ASSESSING A PATIENT'S FLUID STATUS AND/OR SENSITIVITY TO FLUID REMOVAL, CONTROLLER, AND DEVICES

The present invention relates to a method for assessing a patient's sensitivity to fluid removal from his vascular system or to fluid replacement or addition regarding to his hydration state, the method comprising the step of determining a value reflecting the distribution of fluid between at least two distribution spaces of the body of the patient or changes thereof from measured or calculated values, and assessing whether the value fulfils at least one criterion. It also relates to a controller, an apparatus, a device, a digital storage means, a computer program product, and a computer program.

SYSTEM, CHAMBER, AND METHOD FOR FRACTIONATION, ELUTRIATION, AND DECONTAMINATION OF FLUIDS CONTAINING CELLULAR COMPONENTS

A chamber, duct system, and method for separating a selected component from and decontaminating a biological sample, such as a unit of blood product, to be stored for a storage interval between a donation and a subsequent transfusion. The method comprises exposing the biological sample to a first decontamination process prior to the storage interval wherein the first decontamination process is adapted to preserve the at least one component while eliminating and/or inactivating at least a portion of the plurality of contaminants (such as pathogens). The method further comprises exposing the biological sample to a second decontamination subsequent to the storage interval and prior to the transfusion of the biological sample. The second decontamination process is adapted to be capable of preserving the at least one component and inactivating and/or eliminating substantially all of the plurality of contaminants. Separating of the selected components utilizes a chamber comprising at least one ...

INJECTION SYSTEM FOR DELIVERING MULTIPLE FLUIDS WITHIN THE ANATOMY

Devices and systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, a joint or intra-articular space, include a handpiece assembly having a needle extending from its distal end, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medicaments, formulations and/or other fluids or materials contained within vials that are secured to a cassette or other portion of the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

DELIVERY OF ULTRASOUND TO PERCUTANEOUS AND INTRABODY DEVICES

A method and apparatus for reducing morbidity associated with a medical device (105) inserted into the body of a patient. Ultrasonic energy is applied to the device with sufficient intensity to inhibit accretion of biological matter associated with the device while the device is in the body. Typically, the energy is applied to the device in the absence of clinically-observable accretion of biological matter on the device so as to prevent such accretion.

Ultrasound assembly with increased efficacy

A catheter system is disclosed. The catheter system includes a catheter body having an external surface and an ultrasound transducer having a side between a first end and a second end. A first medium is positioned adjacent to the first end of the ultrasound transducer and a second medium is positioned adjacent to the external side of the ultrasound transducer. The second medium is harder than the first medium to encourage flexibility of the catheter body adjacent to the first end of the ultrasound transducer and efficient transmission of ultrasound energy from the external side of the ultrasound transducer.

Ultrasound catheter for providing a therapeutic effect to a vessel of a body

A catheter for use in a vessel of a body is disclosed. The catheter includes an elongated body and a plurality of ultrasound elements coupled to the elongated body. Each of the plurality of ultrasound elements is separated from an adjacent ultrasound element.

Ultrasound plaque emulsion device

A medical device is described that can be used to emulsify and remove atherosclerotic plaque from blood vessels. The device uses a high frequency ultrasound transducer and conical tip to enhance the generation of shear waves that can safely and efficiently emulsify plaque.

Ultrasound method for revascularization and drug delivery

A method and device for improving blood circulation to an area of interest within a patient' heart is described. The method comprises inserting a guidable elongated flexible ultrasound device into a patient's vasculature, applying ultrasonic energy to an area in need of improved circulation, and injecting materials such as angiogenic materials or contrasting agents into the area of interest. The device, suitable for performing the method, comprises an elongated tubular body, a distal head of the elongated tubular body for introducing ultrasonic energy to an area of interest, and a needle to deliver materials to an area of interest.

Acoustic access disconnection systems and methods

An access disconnection system includes: an arterial line; a venous line; a transmitter configured to transmit a sound wave in one of the arterial and venous lines when connected to a patient; a receiver configured to receive the sound wave from the other of the arterial and venous lines when connected to the patient; and electronic circuitry coupled to at least one of the transmitter and receiver, the circuitry configured to send a disconnection output indicative of a change in the sound waves received by the receiver from the transmitter sufficient to expect that an access disconnection of one of the arterial line and venous lines has occurred.

Apparatus for providing light therapy

Methods and apparatuses for providing therapy, including light therapy, to a user positioned within an enclosure are described herein. A method includes generating and selecting therapy settings based on user information and positioning the user within an enclosure having a plurality of light sources. The enclosure is configured to focus light on the user at a location within the enclosure according to selected settings. Post-therapy user information is provided to generate a report regarding the user and may include the user's measured physical attributes, measured spectrum values, reported information, or survey information. Aromatherapy, audio therapy, or air therapy may be additionally provided. An apparatus includes an enclosure with a control system configured to perform a therapy method. An enclosure may be have the shape of an octagon or another shape. A computer readable non-transitory storage media includes instructions for providing therapy to a user positioned within the enclosure ...

Methods, systems, and kits for lung volume reduction

Lung volume reduction is performed in a minimally invasive manner by isolating a lung tissue segment, optionally reducing gas flow obstructions within the segment, and aspirating the segment to cause the segment to at least partially collapse. Further optionally, external pressure may be applied on the segment to assist in complete collapse. Reduction of gas flow obstructions may be achieved in a variety of ways, including over inflation of the lung, introduction of mucolytic or dilation agents, application of vibrational energy, induction of absorption atelectasis, or the like. Optionally, diagnostic procedures on the isolated lung segment may be performed, typically using the same isolation/access catheter.

Handpiece for performing phacoemulsification of ophthalmic lens, has drive element that is provided for producing longitudinal wave, such that longitudinal wave is left itself to directly inject into aspiration fluid

The handpiece (1) has a needle (10) that is arranged with an aspiration spacer (2) for transportation of aspiration fluid (3). A drive element (5) is provided for producing a longitudinal wave, such that the longitudinal wave is left itself to directly inject into the aspiration fluid. The drive element is arranged within the aspiration spacer such that the drive element is brought to be in direct contact with the aspiration fluid. The drive element is provided with piezoelectric elements. A distal extremity (9) of needle is formed from a polymer plastic.

Surgical cassette apparatus

PROCESS Of INACTIVATION BY ULTRASOUNDS Of INFECTIOUS OR PARASITIC AGENTS IN BIOLOGICAL ENVIRONMENTS AND APPLICATIONS OF the PROCESS.

FLUID SKIN TREATMENT SYSTEMS AND METHODS

The present invention relates to devices for dermatology and more particularly to fluid enhanced skin treatment system for skin rejuvenation that can optionally use an abrasive probe for removing epidermal layers while contemporaneously providing for the infusion of therapeutic fluids into the skin.

CONTROL ARRANGEMENT FOR AN OPHTHALMIC SURGICAL SYSTEM

A control arrangement for an ophthalmic surgical system for phacoemulsifying a lens wherein the system includes an aspiration line for drawing off fluid and shattered lens particles of the eye lens and a phaco handpiece having a needle. The aspiration line runs within the needle and is configured to impart ultrasonic energy to the phaco handpiece for shattering the eye lens via a longitudinal vibration of the needle. The control arrangement includes a transmitter configured to irradiate electromagnetic radiation via the aspiration line and a receiver configured to receive at least a part of the radiation; and, a control unit configured to control an absolute value of a parameter of the ophthalmic surgical system in dependence upon the amount of the received electromagnetic radiation. 1. A control arrangement for an ophthalmic surgical system for phacoemulsifying a lens , the system including:an aspiration line for drawing off fluid and shattered lens particles of the eye lens;a phaco handpiece having a needle;said aspiration line running within said needle and being configured to impart ultrasonic energy to said phaco handpiece for shattering said eye lens via a longitudinal vibration of said needle; and,said control arrangement comprising:a transmitter configured to irradiate electromagnetic radiation;a coupling unit having a distal end and being configured to so conduct at least one part of said irradiated electromagnetic radiation to said distal end that said at least one part of said electromagnetic radiation can be coupled into said aspiration line;said distal end being disposed outside of said aspiration line;a receiver configured to receive at least a part of said electromagnetic radiation;a control unit configured to control an absolute value of a parameter of said ophthalmic surgical system in dependence upon the amount of the received electromagnetic radiation; and,{'sup': '2', 'said electromagnetic radiation having a wavelength greater than 750 nanometers ...

DRUG DELIVERY DEVICE

The present disclosure presents systems, devices and methods for injection of drugs, substances and/or chemicals to a patient and for improving their effectiveness once they are injected are disclosed. Additional treatment can be applied to a tissue region on the patient into which a drug (e.g., insulin) is injected, to expose the tissue region to various forms of energy or a substance to improve the drug's pharmacokinetic and/or pharmacodynamic profile. 1. An apparatus for delivering therapeutic fluid to a patient at an injection site , comprising: an injector for injecting the therapeutic fluid to the injection site; and', 'a reservoir for containing the therapeutic fluid;, 'a fluid injection device having a housing, wherein said housing containsa treatment element coupled to said fluid injection device and configured to apply treatment to the injection site;wherein said treatment element is further configured to improve pharmacokinetic and/or pharmacodynamics property of the therapeutic fluid.280-. (canceled) The present invention claims priority to U.S. Provisional Patent Application No. 60/895,518, filed Mar. 19, 2007, U.S. Provisional Patent Application Ser. No. 60/895,519, filed Mar. 19, 2007, U.S. Provisional Patent Application Ser. No. 60/912,698, filed Apr. 19, 2007, U.S. Provisional Patent Application Ser. No. 60/940,721, filed May 30, 2007, U.S. Provisional Patent Application No. 61/016,571, filed Dec. 25, 2007, U.S. Provisional Patent Application No. 61/008,277, filed Dec. 18, 2007 and U.S. Provisional Patent Application No. 61/010,758, field Jan. 10, 2008, and U.S. patent application Ser. No. 11/812,230, filed Jun. 21, 2007, the disclosures of which are incorporated herein by reference in their entireties.1. Field of the InventionThe present invention relates to systems and methods for delivering drugs to a patient. In particular, the present invention relates to systems and methods for subcutaneous injection of a medicament and using one or more ...

Method for reducing biofilm formation

A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.

A DEVICE FOR PERFORMING DIAGNOSTICS AND/OR THERAPY

УСТРОЙСТВА И СПОСОБЫ ЛИПОСАКЦИИ И ОКРУЖАЮЩИЕ ЭЛЕМЕНТЫ АСПИРАЦИОННОЙ СИСТЕМЫ И СПОСОБЫ

FIELD: medical equipment. SUBSTANCE: device for ultrasonic liposuction has ultrasonic vibrator. Vibrator has ultrasonic probe with proximal end connected with ultrasonic vibrator, and distal end. Matching device for usage together with vibrator has mounting of handle to mount in on top of ultrasonic vibrator and fixation relatively it. Mounting of handle has sealing to be air-proof relatively vibrator and probe. Sealing forms first liquid chamber adjoining proximal end of probe between mounting of handle and vibrator. Mounting of handle also has aspiration pipe connected to first chamber for passing liquid through and made for connection with aspiration unit, and pressure rejection opening. Opening communicates with first chamber for letting liquid through to control air flow from first chamber. Suck-out pipe is connected with mounting of handle; pipe goes on top of probe disposed in it including distal end of probe. Suck-out pipe is made to form passage for liquid between suck-out pipe and probe which communicates with first chamber for letting liquid through. Space between end of ultrasonic probe and end of suck-out pipe forms the second chamber. Suck-out pipe has at least one opening at its distal end, which opening communicates with second chamber for letting liquid through. When doing ultrasonic liposuction, position of suck-out pipe is adjusted relatively probe and along its axis. EFFECT: improved efficiency; higher safety at use. 30 cl, 5 dwg ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß RU (19) (11) 2 300 393 (13) C2 (51) ÌÏÊ A61M 1/00 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÎÏÈÑÀÍÈÅ ÈÇÎÁÐÅÒÅÍÈß Ê ÏÀÒÅÍÒÓ (21), (22) Çà âêà: 2004117209/14, 08.11.2002 (72) Àâòîð(û): ÒÀÇÈ Ýëü Õàññàí (MA) (24) Äàòà íà÷àëà îòñ÷åòà ñðîêà äåéñòâè ïàòåíòà: 08.11.2002 (73) Ïàòåíòîîáëàäàòåëü(è): ÒÀÇÈ Ýëü Õàññàí (MA) R U (30) Êîíâåíöèîííûé ïðèîðèòåò: 08.11.2001 (ïï.1-10, 12-21, 23-26, 28, 29) US 60/337,045 07.11.2002 (ïï.11, 22, 27) US 10/289,569 (43) ...

Tissue treatment device

Surgical cassette apparatus

A surgical cassette arrangement is provided. The arrangement includes a flow selector valve (202) configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir (204) fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector (206) fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls irrigation and aspiration flow to the handpiece and ocular region.

Systems and methods for a device using a statistical model trained on annotated signal data

In some aspects, a device includes a sensor configured to detect a signal from the brain of the person and a plurality of transducers, each configured to apply to the brain an acoustic signal. One of the plurality of transducers is selected using a statistical model trained on signal data annotated with one or more values relating to identifying a health condition.

dispositivo de indução eletromagnética e método para ativação de um tecido alvo

SYSTEMS AND METHODS FOR A DEVICE USING A STATISTICAL MODEL TRAINED ON ANNOTATED SIGNAL DATA

In some aspects, a device includes a sensor configured to detect a signal from the brain of the person and a plurality of transducers, each configured to apply to the brain an acoustic signal. One of the plurality of transducers is selected using a statistical model trained on signal data annotated with one or more values relating to identifying a health condition.

Methods, systems, and kits for lung volume reduction

Lung volume reduction is performed in a minimally invasive manner by isolating a lung tissue segment, optionally reducing gas flow obstructions within the segment, and aspirating the segment to cause the segment to at least partially collapse. Further optionally, external pressure may be applied on the segment to assist in complete collapse. Reduction of gas flow obstructions may be achieved in a variety of ways, including over inflation of the lung, introduction of mucolytic or dilation agents, application of vibrational energy, induction of absorption atelectasis, or the like. Optionally, diagnostic procedures on the isolated lung segment may be performed, typically using the same isolation/access catheter.

Ultrasound assembly with increased efficacy

A catheter system is disclosed. The catheter system includes a catheter body having an external surface and an ultrasound transducer having a side between a first end and a second end. A first medium is positioned adjacent to the first end of the ultrasound transducer and a second medium is positioned adjacent to the external side of the ultrasound transducer. The second medium is harder than the first medium to encourage flexibility of the catheter body adjacent to the first end of the ultrasound transducer and efficient transmission of ultrasound energy from the external side of the ultrasound transducer.

Steuerungsvorrichtung für ein ophthalmochirurgisches System

Steuerungsvorrichtung (101; 102) für ein ophthalmochirurgisches System (100; 200) zur Phakoemulsifikation einer Augenlinse (2), aufweisend:- eine Aspirationsleitung (5) für Fluid (22), welche geeignet ist, elektromagnetische Strahlung (11) weiterzuleiten,- einen Sender (10), welcher geeignet ist, elektromagnetische Strahlung (11) abzustrahlen, wobei der Sender (10) so angeordnet ist, dass die abgestrahlte elektromagnetische Strahlung (11) in die Aspirationsleitung (5) einkoppelbar ist,- einen Empfänger (14), welcher geeignet ist, die vom Sender (10) abgestrahlte elektromagnetische Strahlung (11) mindestens teilweise zu empfangen,- eine Steuerungseinheit (16), mit welcher sich in Abhängigkeit vom Betrag der empfangenen Strahlung (13; 25) ein Betrag eines Parameters des ophthalmochirurgischen Systems (100; 200) steuern lässt, wobei die Aspirationsleitung (5) eine Leitungs-Innenwand (23) aufweist, welche die in die Aspirationsleitung (5) eingekoppelte elektromagnetische Strahlung (11) reflektiert ...

FETTABSAUGVORRICHTUNGEN UND UMGEBENDE ABSAUGSYSTEME

MEDICATION FOR TOPICAL APPLICATION BY ULTRASOUND

Tissue treatment device

SYSTEMS AND METHODS FOR A WEARABLE DEVICE FOR TREATING A HEALTH CONDITION USING ULTRASOUND STIMULATION

In some aspects, a device wearable by or attached to or implanted within a person includes a sensor configured to detect an electroencephalogram (EEC) signal from the brain of the person and a transducer configured to apply to the brain a low power, substantially non-destructive ultrasound signal.

ELECTRO-MAGNETIC INDUCTION DEVICE AND METHOD OF ACTIVATING A TARGET TISSUE

An electro-magnetic induction device (2) for activating a target tissue in a human or animal body via its muscular or neural system comprises: (i) an electro-magnetic field generator (21) with a coil design (211) configured to generate an electro-magnetic field (212) having a targeted shape (213), (ii) a mounting arrangement (22) holding the coil design (211) of the electro-magnetic field generator (21) at the human or animal body, (iii) a sensor member (4) configured to detect an activation of the target tissue, (iv) an electro-magnetic field adjustment mechanism (21) configured to automatically adjust the position of the electro-magnetic field (212) generated by the coil design (211) and to adjust a field strength of the electro-magnetic field (212) generated by the coil design, and (v) a calibration unit (31) in communication with the sensor member (4) and with the electro-magnetic field adjustment mechanism (21). The calibration unit (31) is configured (a) to control the electro-magnetic ...

METHOD AND DEVICE FOR DRUG DELIVERY

Systems, devices, and methods for delivering a therapeutic substance into the body of a patient are disclosed. The device includes an infusion catheter for insertion into tissue of a patient and delivery of a therapeutic substance to an infused region surrounding the insertion site. The device further includes a catheter securing element for adhering to the skin of the patient. Additionally, the device includes a housing containing a substance delivery device for infusing the substance into the infusion catheter, and a sensor built into the housing for detecting infusion of the substance. Further, the device includes a treatment element for applying a treatment in a vicinity of the infused region to modify a pharmacokinetic and/or pharmacodynamic profile of the substance, and a controller unit in communication with the treatment element. The controller initiates application of the treatment by the treatment element upon detecting the beginning of infusion.

APPARATUS FOR PROVIDING LIGHT THERAPY

Methods and apparatuses for providing therapy, including light therapy, to a user positioned within an enclosure are described herein. A method includes generating and selecting therapy settings based on user information and positioning the user within an enclosure having a plurality of light sources. The enclosure is configured to focus light on the user at a location within the enclosure according to selected settings. Post-therapy user information is provided to generate a report regarding the user and may include the user's measured physical attributes, measured spectrum values, reported information, or survey information. Aromatherapy, audio therapy, or air therapy may be additionally provided. An apparatus includes an enclosure with a control system configured to perform a therapy method. An enclosure may be have the shape of an octagon or another shape. A computer readable non-transitory storage media includes instructions for providing therapy to a user positioned within the enclosure ...

System and method for treating a wound using ultrasonic debribement

A wound treatment system includes a distribution manifold, a reduced pressure source, a fluid delivery source, and an ultrasonic energy transducer. Reduced pressure and fluid delivery may be applied to the wound through the distribution manifold. The ultrasonic energy transducer is configured to deliver ultrasonic energy to the wound to debride the wound. The ultrasonic energy transducer may be either a piezoelectric transducer or a surface acoustic wave device. The ultrasonic energy transducer may be placed adjacent to the distribution manifold to deliver ultrasonic energy directly to the wound or may be coupled to an acoustically-conducting membrane positioned between the distribution manifold and the wound.

Three-dimensional porous film contact layer with improved wound healing

A wound dressing has a micro-architecture to produce appropriate strains in cells to promote the healing a wound. The apparatus includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around the wound, a vacuum source in fluid communication with the reservoir and suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound, and a porous structure positioned in contact with the wound for delivering micro-mechanical forces to localized areas of the wound. The porous structure comprises a three-dimensional film material having directional apertures formed therein.

DRUG DELIVERY DEVICE

The present disclosure presents systems, devices and methods for injection of drugs, substances and/or chemicals to a patient and for improving their effectiveness once they are injected are disclosed. Additional treatment can be applied to a tissue region on the patient into which a drug (e.g., insulin) is injected, to expose the tissue region to various forms of energy or a substance to improve the drug's pharmacokinetic and/or pharmacodynamic profile.

Ultrasound catheter for providing a therapeutic effect to a vessel of a body

The invention relates to a catheter system. The system comprises a catheter body having a chamber containing a low acoustic impedance medium. The catheter body includes an elongated body with an external surface and an ultrasound transducer having an external side between a first end and a second end. The ultrasound transducer is positioned over the external surface of the elongated body such that the first end is adjacent to the chamber.

Ultrasound method for revascularization and drug delivery

A method and device for improving blood circulation to an area of interest within a patient' heart is described. The method comprises inserting a guidable elongated flexible ultrasound device into a patient's vasculature, applying ultrasonic energy to an area in need of improved circulation, and injecting materials such as angiogenic materials or contrasting agents into the area of interest. The device, suitable for performing the method, comprises an elongated tubular body, a distal head of the elongated tubular body for introducing ultrasonic energy to an area of interest, and a needle to deliver materials to an area of interest.

Method and apparatus for treatment of intracranial hemorrhages

An ultrasound catheter with a lumen for fluid delivery and fluid evacuation, and an ultrasound source is used for the treatment of intracerebral or intraventricular hemorrhages. After the catheter is inserted into a blood clot, a lytic drug can be delivered to the blood clot via the lumen while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the lumen.

Ultrasound catheter for providing a therapeutic effect to a vessel of a body

The invention relates to a catheter system. The system comprises a catheter body having a chamber containing a low acoustic impedance medium. The catheter body includes an elongated body with an external surface and an ultrasound transducer having an external side between a first end and a second end. The ultrasound transducer is positioned over the external surface of the elongated body such that the first end is adjacent to the chamber.

Acoustic access disconnection systems and methods

An access disconnection system includes a blood treatment machine including a housing, an access site detection housing separate from the blood treatment machine housing, a transmitter positioned in the access site housing and configured to transmit an ultrasound wave into a blood stream of a patient, a receiver positioned in the access site housing and configured to receive a reflection of the ultrasound wave from the blood stream of the patient; and electronic circuitry in communication with the transmitter and the receiver. The electronic circuitry is supported by the access site detection housing, and the transmitter is configured to send a wireless disconnection output to the blood treatment machine. The disconnection output is indicative of a change in the reflected ultrasound wave received by the receiver sufficient to expect that an access disconnection of one of the arterial line and the venous line has occurred.

ULTRASOUND DEVICE WITH TOPICAL CONDUCTING MEDIUM

A dermal device for providing ultrasound therapy to skin is provided including: a transducer assembly including housing structure having an inner surface defining a void and configured to contact an outer portion of an area of skin of a user without contacting an inner portion of the area of skin; and an ultrasound transducer supported by the housing and configured to be disposed proximate the void, wherein the ultrasound transducer is configured to provide ultrasound energy with a focal point towards the skin. 1. A dermal device for providing ultrasound therapy to skin , the dermal device comprising:a transducer assembly including housing structure having an inner surface defining a void and configured to contact an outer portion of an area of skin of a user without contacting an inner portion of the area of skin; andan ultrasound transducer supported by the housing and configured to be disposed proximate the void,wherein the ultrasound transducer is configured to provide ultrasound energy with a focal point towards the skin.2. The dermal device of claim 1 , wherein the ultrasound transducer is configured to be adjusted within the device housing relative to the skin claim 1 ,wherein the focal point is modified based on the adjustment.3. The dermal device of claim 2 , wherein the ultrasound transducer is adjusted by adjusting the housing claim 2 ,wherein the focal point is modified based on the adjustment of the housing.4. The dermal device of claim 1 , wherein a dermal topical is configured fill the void and to serve as an ultrasound conductive medium and a therapeutic agent claim 1 ,wherein the dermal topical is one of a cosmetic, toner, cream, serum, or similar agent.5. The dermal device of claim 1 , wherein the dermal topical has a viscosity similar to that of water.6. A system for providing ultrasound therapy to skin claim 1 , the system comprising:an ultrasound transducer configured to interface with one of at least two cartridges; anda cartridge having a ...

METHOD AND APPARATUS FOR AUTOMATED ACTIVE STERILIZATION OF FULLY IMPLANTED DEVICES

The current invention provides this advance in infection control via its unique application of active sterilization to a catheter or implant. While most catheters, and many implants, are passive devices, the current invention will provide an active component as a integral part of the implanted catheter or device to continuously or intermittently sterilize the exposed surfaces/areas of the device. This active sterilization may be accomplished by a variety of mechanisms, including, application of heat, RF, microwave, ultrasound, ultraviolet radiation or other energy capable of sterilizing the device or dislodging any problematic Biofilm that may form. The active sterilization may also employ the pumping of a sterilizing chemical from all attached drug reservoir, the use of electricity or freezing temperatures or any other mechanism for either inhibiting, killing or dislodging any infectious material in contact with the implant. One major advantage of this design is that through the use of small, battery powered or inductively powered sterilization element, the implanted catheter or device can be effectively sterilized without requiring the standard removal surgery, waiting period, then replacement of the infected device. This is expected to translate into greatly improved outcomes (particularly for devices where infection may be catastrophic, ie a prosthetic knee or hip), greatly improved costs, and greatly improved longevity of susceptible devices (ie IV ports, etc.). 1. A sterilization system for sterilizing, an implanted prosthesis, comprising a housing sized for implantation within a patient body and having an energy generator therewithin, wherein the energy generator is configured to deliver anti-infective energy or agents through one or more catheters fluidly coupled to the housing. This application is a continuation of U.S. patent application Ser. No. 121702,977 filed Feb. 9, 2010, which is a continuation of International Pat. App, Ser. No. PCT/US2008/073279 ...

WOUND TREATMENT APPARATUS AND METHOD

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which ⋅may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus. 1. (canceled)2. A wound dressing comprising:a backing layer configured to positioned over a wound and form a closure over the wound;a boss configured to reinforce the backing layer;an inlet tube configured to pass through the backing layer and the boss, a first end of the inlet tube configured to be disposed outside a volume partially enclosed by the backing layer, and a second end of the inlet tube configured to be disposed in the volume partially enclosed by the backing layer; andan ultrasonic transducer configured to be mounted on the boss, the ultrasonic transducer comprising a flow passage configured to communicate irrigation fluid flowing through the inlet tube into the wound.3. The wound dressing of claim 2 , wherein the ultrasonic transducer is configured to be mounted on a surface of the boss configured to face the wound.4. The wound dressing of claim 2 , wherein a portion of the boss is configured to extend through the backing layer.5. The wound dressing of claim 2 , further comprising an inlet manifold comprising a plurality of apertures in fluid communication with the inlet tube.6. The wound dressing of claim 5 , wherein the inlet manifold comprises a tree of tubules that fluidically connects the plurality of apertures to the inlet tube.7. ...

SYSTEMS, DEVICES, AND METHODS FOR ASPIRATING BIOLOGICAL MATERIAL FROM A BODY LUMEN

An intraluminal system for aspirating biological material from a lumen of a patient includes a disposable intraluminal device having a proximal portion and a distal portion. The system includes a disposable pump configured to aspirate the biological material from the lumen of the patient. The disposable pump is coupled to the proximal portion of the intraluminal device. The disposable pump comprises a pump chassis that houses: an inlet port configured to sealably attach to the proximal portion of the intraluminal device; an outlet port configured to expel the aspirated biological from the pump; and a flow controller configured to adjust a fluid flow through the pump, wherein the pump chassis is sized and shaped to be manually supported by a user. 1. An intraluminal system for aspirating biological material from a lumen of a patient , comprising:a disposable intraluminal device comprising a distal portion configured to be positioned within the lumen of the patient and a proximal portion in fluid communication with the distal portion and positioned outside of the patient; and an inlet port configured to sealably attach to the proximal portion of the intraluminal device;', 'an outlet port configured to expel the aspirated biological from the pump;', 'a flow controller configured to adjust a fluid flow through the pump;', 'an actuator;', 'a first pump chamber;', 'a second pump chamber separate from the first pump chamber; and', 'a dual displacement adapter coupled to the actuator such that the actuator is configured to drive the dual displacement adapter to pump fluid through each of the first pump chamber and the second pump chamber in an alternating fashion, and, 'a disposable pump configured to aspirate the biological material from the lumen of the patient, the disposable pump coupled to the proximal portion of the intraluminal device and comprising a pump chassis that houseswherein the pump chassis is sized and shaped to be manually supported by a user.2. The ...

COLD PLASMA GENERATING DEVICES, SYSTEMS, AND METHODS

A system and method for cosmetic treatment of a region of a biological surface using cold atmospheric plasma is presented. In one embodiment, a method of treatment of a region of a biological surface with cold plasma includes: selecting a post-treatment formulation; and applying the post-treatment formulation to the region pre-treated by the cold plasma. 1. A method of treatment of a region of a biological surface with a cold plasma , the method comprising:selecting a post-treatment formulation; andapplying the post-treatment formulation to the region pre-treated by the cold plasma.2. The method of claim 1 , further comprising:generating the cold plasma between a plasma treatment device and the region; andprior to applying the post-treatment formulation, switching off the cold plasma.3. The method of claim 2 , further comprising:activating an auxiliary treatment device, wherein the auxiliary treatment device is selected from a group consisting of (i) a vibration device, (ii) a source of ultrasound, (iii) a light source configured to illuminate the region, and (iv) a source of air directed to the region; andcontaining the cold plasma between the plasma treatment device and the region by a skirt disposed at least partially about the cold plasma.4. The method of claim 1 , further comprising:selecting a pre-treatment formulation;applying the pre-treatment formulation to the region;generating the cold plasma between a plasma treatment device and the pre-treatment formulation;switching off the cold plasma; andremoving the pre-treatment formulation from the region.5. The method of claim 4 , further comprising:prior to applying the pretreatment formulation to the region, treating the pre-treatment formulation by discharging the cold plasma into the pre-treatment formulation;during generating the cold plasma between a plasma treatment device and the region, sensing one or more treatment parameters with one or more sensors;determining a plasma dose from the treatment ...

System for reducing local discomfort

A device for targeted delivery of a substance to an airway may include a conduit and at least two applicators. The conduit may include a proximal end and a bifurcated distal portion having two distal ends. Each applicator may be coupled with one of the distal ends of the conduit and may be configured to direct the substance out of the applicator toward one of two sides of an airway. A method for targeted delivery of a substance to an airway may involve advancing a substance delivery device into the airway, contacting two sides of the airway with at least two applicators of the substance delivery device, such that each applicator contacts the airway near a glossopharyngeal nerve and/or a superior laryngeal nerve on each of the two sides of the airway, and delivering the substance through the applicators to contact the airway along the two sides.

SYSTEMS AND METHODS FOR TREATING CANCER AND/OR AUGMENTING ORGAN FUNCTION

Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed. 1. A medical system , comprising:a microsurgical tool configured for percutaneous introduction and having a distal tip segment positionable with respect to a target neural structure, the microsurgical tool including at least two zones adjacent the distal tip segment, at least a first of the two zones including a physiological sensor configured to emit a signal representative of physiological data of the neural structure and at least a second of the two zones including a stimulatory element configured to apply stimulation to the neural structure; and to determine a condition of the neural structure before, during or subsequent to application of stimulation to the neural structure by the stimulatory element; and', 'to control operation of the stimulatory element based on the determined condition of the neural structure., 'a controller to control operation of each of the two zones based on the physiological data obtained by the physiological sensor, the controller configured2. The medical system of claim 1 , wherein the stimulatory element of the second zone is one of: an energy delivery element; and a substance delivery element.3. The medical system of claim 2 , wherein the energy delivery element is configured to deliver energy adjacent the neural structure claim 2 , the energy being at least one of thermal energy claim 2 , radio frequency current claim 2 , microwave current claim 2 , ultrasound claim 2 , HIFU (high intensity focused ultrasound) claim 2 , radiation claim 2 , and cryotherapy.4. The medical system of claim 2 , wherein the substance delivery element is configured to deliver a substance adjacent the neural structure claim 2 , the substance being at least one of a medicament claim ...

Flow Balancing Devices, Methods, and Systems

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described. 1. A medical treatment system , comprising:a flow balancing fluid management element configured to pump fluid from a patient interface device during a treatment and configured to pump fluid into the patient interface device during the treatment, the flow balancing fluid management element including a synchronization mechanism that is configured to proportion flow to and from the patient interface device in a predefined ratio during the treatment;the patient interface device being a device that interfaces with a patient fluid compartment including at least one of a dialyzer, a hemofilter, a hemodiafilter, an ultrafilter, and a plasmapheresis device;a proportioning bypass channel that includes a proportioning bypass pump and configured to pump fluid to or from the patient interface device in a predefined amount that has a predefined relationship to flows in said flow balancing fluid management element so as to produce a predefined net withdrawal from, or infusion into, a patient;a controller configured to control at least the proportioning bypass pump and including a processor programmed to regulate a rate of flow through the proportioning bypass pump to achieve the predefined net withdrawal from, or infusion into, the patient; andan infusion circuit connectable to a source of fluid and including an infusion circuit pump and connected to one or both of blood lines connected to a patient access, whereinat least a portion of the infusion circuit is selectively connectable to the proportioning bypass channel such that the ...

SYSTEM FOR REDUCING LOCAL DISCOMFORT

A device for targeted delivery of a substance to an airway may include a conduit and at least two applicators. The conduit may include a proximal end and a bifurcated distal portion having two distal ends. Each applicator may be coupled with one of the distal ends of the conduit and may be configured to direct the substance out of the applicator toward one of two sides of an airway. A method for targeted delivery of a substance to an airway may involve advancing a substance delivery device into the airway, contacting two sides of the airway with at least two applicators of the substance delivery device, such that each applicator contacts the airway near a glossopharyngeal nerve and/or a superior laryngeal nerve on each of the two sides of the airway, and delivering the substance through the applicators to contact the airway along the two sides. 1. A device for targeted delivery of a substance to an airway , the device comprising: a conduit comprising a proximal end and a bifurcated distal portion having two distal ends , wherein the proximal end is configured to be coupled with a source of the substance; and at least two applicators , each applicator coupled with one of the distal ends of the conduit , wherein each applicator is configured to direct the substance out of the applicator toward one of two sides of an airway.230-. (canceled) This application is a divisional application of U.S. Nonprovisional application Ser. No. 14/099,233, filed on Dec. 6, 2013, issued as U.S. Pat. No. 9,409,003, which claimed the benefit of U.S. Provisional Patent Application Nos. 61/734,713, entitled “System for Reducing Local Discomfort,” as filed on Dec. 7, 2012; 61/808,142, entitled “System to Reduce Discomfort in the Upper Airway,” as filed Apr. 3, 2013; and 61/823,070, entitled “System to Reduce Discomfort in the Upper Airway,” as filed May 14, 2013. The full disclosures of all the above-referenced applications are hereby incorporated by reference herein.Pain, agitation, gagging ...

Method And Device For Drug Delivery

Systems, devices and methods for delivery of a chemical substance to the body of the patient are provided. Such embodiments may include an infusion catheter configured to be inserted into tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.

Product Warming Device

A product warming device comprises an outer housing, a temperature regulating device disposed within the outer housing, and a heating system disposed within the outer housing. The temperature regulating device includes a first warming assembly defining a first package receiving space and a second warming assembly defining a second package receiving space. A first warming body of the first warming assembly has an outer wall recessed section expanding an upper opening of the first package receiving space. The heating system is adapted to heat the first warming assembly and the second warming assembly to a temperature set point. 1. A product warming device , comprising:an outer housing;a temperature regulating device disposed within the outer housing and having:a first warming assembly defining a first package receiving space and having, a first warming body with an outer wall recessed section expanding an upper opening of the first package receiving space; anda second warming assembly defining a second package receiving space; anda heating system disposed within the outer housing and adapted to heat the first warming assembly and the second warming assembly to a temperature setpoint.2. The product warming device of claim 1 , further comprising a lid pivotally attached to the outer housing.3. The product warming device of claim 2 , wherein the lid includes a transparent lid body and a hinge device rotatably connected to the outer housing.4. The product warming device of claim 1 , wherein the outer housing includes a base housing and a back cover.5. The product warming device of claim 4 , wherein the base housing includes a front side claim 4 , a back side claim 4 , and opposite sidewalls connecting the front side to the back side to define a temperature regulating device receiving space there between.6. The product warming device of claim 5 , wherein the base further includes an actuation device receiving space extend through the front side thereof.7. The product ...

SYSTEMS AND METHODS FOR TREATING CANCER AND/OR AUGMENTING ORGAN FUNCTION

Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed. 1. A method , comprising:blocking at least one of one or more nerves and one or more lymphatic ducts coupled to at least one of a tumor and a metastatic cell within a body.2. The method of claim 1 , wherein the blocking step isolates at least one of the tumor and the metastatic cell within the body.3. The method of claim 1 , wherein the blocking step alters growth rates of at least one of the tumor and metastatic cell within the body.4. The method of claim 1 , wherein the blocking step is performed by injecting a neurolytic agent into at least one of the one or more nerves claim 1 , the one or more lymphatic ducts claim 1 , and nearby tissue.5. The method of claim 1 , wherein the blocking step further comprises injecting a mild inflammatory agent into at least one of the nerves and the lymphatic ducts.6. The method of claim 1 , wherein at least one of the one or more nerves and the one or more lymphatic ducts being blocked is at least 10 mm claim 1 , 20 mm claim 1 , or 25 mm in length.7. The method of claim 1 , further comprising accessing at least one of the one or more nerves and the one or more lymphatic ducts via one of a nearby artery claim 1 , a vein and a duct.8. The method of claim 1 , wherein the blocking step further comprises altering the structure of a perineural sheath of one or more nerves.9. The method of claim 1 , wherein the blocking step further comprises performing architectural destruction of at least one of nerve tissue and lymphatic ductal tissue via inflammation.10. The method of claim 1 , wherein the blocking step further comprises forming scar tissue along at least one of the one or more nerves and the one or more lymphatic ducts.11. The method of claim 1 , wherein ...

SYSTEMS AND METHODS FOR REGULATING ORGAN AND/OR TUMOR GROWTH RATES, FUNCTION, AND/OR DEVELOPMENT

A system for controlled neuromodulation procedures is disclosed. A system for controlled micro ablation procedures is disclosed. Systems and methods for imaging, monitoring, stimulating, and/or ablating neurological structures coupled to one or more organs of the lower urinary tract (LUT) are disclosed. Such processes may be used to alter the hormonal secretions from one or more organs, to modulate the growth of an organ, alter the growth rate or rate of perineural invasion of a tumor, or the like. In particular such processes may be used to slow, halt and/or reverse the growth of a prostate gland or a prostate tumor. 1. A method , comprising:blocking at least one of one or more nerves and one or more lymphatic ducts coupled to at least one of a tumor and a metastatic cell within a body.2. The method of claim 1 , wherein the blocking step isolates at least one of the tumor and the metastatic cell within the body.3. The method of claim 1 , wherein the blocking step alters growth rates of at least one of the tumor and metastatic cell within the body.4. The method of claim 1 , wherein the blocking step is performed by injecting a neurolytic agent into at least one of the one or more nerves claim 1 , the one or more lymphatic ducts claim 1 , and nearby tissue.5. The method of claim 1 , wherein the blocking step further comprises injecting a mild inflammatory agent into at least one of the nerves and the lymphatic ducts.6. The method of claim 1 , wherein at least one of the one or more nerves and the one or more lymphatic ducts being blocked is at least 10 mm claim 1 , 20 mm claim 1 , or 25 mm in length.7. The method of claim 1 , further comprising accessing at least one of the one or more nerves and the one or more lymphatic ducts via one of a nearby artery claim 1 , a vein and a duct.8. The method of claim 1 , wherein the blocking step further comprises altering the structure of a perineural sheath of one or more nerves.9. The method of claim 1 , wherein the blocking ...

Concepts for catheter control and stabilization

A catheter guide device configured to facilitate precise placement of a downstream end of a catheter within a patient. The catheter guide device comprises a torque assembly configured to frictionally engage an exterior surface of a catheter and a hub configured to engage a catheter sheath and thereby prevent rotation of the catheter sheath relative to the hub. The torque assembly is rotatably secured to the hub such that rotating the torque assembly relative to the hub rotates the catheter relative to the catheter sheath and thereby moves the downstream end of the catheter within the patient. The hub additionally comprises a detent mechanism configured to engage a plurality of gear teeth on an exterior surface of the torque assembly to thereby impede unintended rotation of the torque assembly relative to the hub.

FLOW CONTROL SYSTEM

A flow control system may include an inner nosecone having an inner nosecone distal end and an inner nosecone proximal end, an outer nosecone having an outer nosecone distal end and an outer nosecone proximal end, an aperture of the outer nosecone, a gasket having a gasket distal end and a gasket proximal end, a gasket aperture of the gasket, a gasket seal of the gasket, a flow control mechanism having a flow control mechanism distal end and a flow control mechanism proximal end, and a control aperture of the flow control mechanism. A rotation of the flow control mechanism about the gasket may be configured to decrease an aspiration flow rate. A rotation of the flow control mechanism about the gasket may be configured to increase an aspiration flow rate. 1. A method comprising:rotating a flow control mechanism about a gasket in a first direction;positioning a portion of a control aperture over a portion of a gasket aperture; anddecreasing an aspiration flow rate of an aspiration handpiece.2. The method of further comprising:covering the portion of the control aperture positioned over the portion of the gasket aperture; andincreasing the aspiration flow rate of the aspiration handpiece.3. The method of further comprising:rotating the control aperture about the gasket in a second direction;positioning the portion of the control aperture over a portion of a gasket seal; andincreasing the aspiration flow rate of the aspiration handpiece.4. The method of wherein a covering of the portion of the control aperture disposed over the portion of the first gasket aperture is configured to increase the aspiration flow rate.5. The method of wherein the rotation of the flow control mechanism about the gasket in the first direction is configured to increase a pressure within a flow control channel of a handpiece.6. The method of wherein the rotation of the flow control mechanism about the gasket in the first direction is configured to increase a pressure within an aspiration ...

Systems, Devices, and Methods For Thrombolysis

Disclosed herein are systems, devices, and methods for thrombolysis. For example, a medical device for thrombolysis can include a conduit, a supply reservoir, and a waste reservoir. The conduit can be configured to insert into a lumen of a venous access device having an intraluminal clot. The conduit can include a supply lumen configured to convey an aqueous thrombolytic composition from the supply reservoir through an opening in a distal-end portion of the conduit to the intraluminal clot. The waste reservoir can be configured to collect waste from the lumen of the venous access device including fibrin fragments, platelets, red blood cells, or spent solution of the thrombolytic composition used to break down the intraluminal clot. Administering a thrombolytic composition in accordance with the disclosed systems, devices, and methods can break down clots more quickly than at least the common 3-way stopcock method. 1. A medical device for thrombolysis , comprising:a conduit configured to insert into a lumen of a venous access device, the conduit including a supply lumen configured to convey an aqueous thrombolytic composition from a supply reservoir thereof through an opening in a distal-end portion of the conduit for administration of the thrombolytic composition to an intraluminal clot in the lumen of the venous access device;a connector coupled to a proximal-end portion of the conduit, the connector configured to fluidly connect the supply reservoir to the supply lumen of the conduit; anda waste reservoir configured to fluidly connect to the lumen of the venous access device, the waste reservoir configured to collect waste from the lumen of the venous access device including fibrin fragments, platelets, red blood cells, or spent solution of the thrombolytic composition used to break down the intraluminal clot in the lumen of the venous access device.2. The medical device of claim 1 , further comprising the supply reservoir optionally pre-filled with the ...

ARRANGEMENT AND METHOD FOR THE IN-VITRO and IN-VIVO TREATMENT OF BRONCHIAL TUMORS

The invention relates to an arrangement and method for the in-vitro and in-vivo treatment of bronchial tumors. 113323445440424154012424112333540. Arrangement for the in-vitro- and in-vivo treatment of lung tumors comprising a ventilation and respirator system () for a part of the lung to be provided with a gas for respiration purposes () , a system for the controlled ventilation and flooding () for a part of the lung to be flooded with a liquid () , a therapy system () and a central control unit () , whereby the therapy system () consists of at least one therapeutic ultrasound transducer () , an imaging-monitoring system () and a temperature-monitoring system () , and the central control unit () has a data-transferring connection to the therapeutic ultrasonic transducer () , the respirator system () , the device for controlled ventilation and flooding () , the imaging-monitoring system () and the temperature-monitoring system () , wherein the respirator system () and the device for controlled ventilation and flooding () have a gas- and liquid-conducting connection to a lung tube () , the lung tube () can be inserted into a lung containing a lung tumor () in an intratracheal manner , and therapeutic ultrasound doses can be administered by the ultrasonic transducer ().2513389. Arrangement for the in-vitro and in-vivo treatment of lung tumors according to claim 1 , characterized in that the control unit () has an information-transmitting connection to at least one control element () by means of which gas- and liquid flows can be introduced in a controlled manner into the lung tube () via at least one supply line (; ).333031303132. Arrangement for the in-vitro and in-vivo treatment of lung tumors according to claim 1 , characterized in that the lung tube () consists of at least two lung tube connections (; ) claim 1 , with at least one lung tube connection (; ) being provided with a block ().4405. Arrangement for the in-vitro and in-vivo treatment of lung tumors ...

Methods and Apparatus for Inducing or Modifying Sleep

A neuromodulator may output stimuli that causes a user to fall asleep faster than the user would in the absence of the stimuli. Alternatively, the stimuli may modify a sleep state or behavior associated with a sleep state, or may cause or hinder a transition from a waking state to a sleep state or from a sleep state to another sleep state. The neuromodulator may take electroencephalography measurements. Based on these measurements, the neuromodulator may detect, in real time, instantaneous amplitude and instantaneous phase of an endogenous brain signal. The neuromodulator may output stimulation that is, or that causes sensations which are, phase-locked with the endogenous brain signal. In the course of calculating instantaneous phase and amplitude, the neuromodulator may perform an endpoint-corrected Hilbert transform. The stimuli may comprise auditory, visual, electrical, magnetic, vibrotactile or haptic stimuli.

DEVICE SYSTEM AND METHOD FOR TRANS-CRANIAL FOCUSED ULTRASOUND WITHOUT HAIR SHAVING

Device for shave-free trans-cranial focused ultrasound (FUS) treatment and method for using same, the device including a scalp cover having a first inlet configured to allow supply of a gas into the scalp cover, and an outlet configured to allow outflow of ambient air contained within the scalp cover when the gas is being supplied, such that the ambient air contained within the scalp cover is replaced by the supplied gas. 135.-. (canceled)36. A method for shave-free trans-cranial focused ultrasound (FUS) treatment , the method comprising;placing a scalp cover on a head of a subject in need of trans-cranial FUS, such that said scalp cover essentially seals around the subject's scalp;supplying a gas into the scalp cover such that ambient air covering the patient's scalp is replaced by the supplied gas; wherein the gas has a higher solubility in water than the ambient air;sending a flow of an aqueous fluid into the scalp cover such that the subject's hair is submerged and/or wet; andproviding a trans-cranial focused ultrasound (FUS) treatment to the subject.37. The method of claim 36 , wherein the trans-cranial focused ultrasound (FUS) treatment comprises high-intensity focused ultrasound (HIFU) claim 36 , low-intensity focused ultrasound (LIFU) claim 36 , FUS-induced BBB opening or FUS-mediated neuromodulation.3836. The method of claim 36 , further comprising administering a contrast agent prior to the treatment.3936. The method of claim 36 , further comprising administering a drug during or after the treatment.4036. The method of claim 36 , wherein the gas has a solubility in water above 1 g/L at 25° C. at 100 kPA.41. The method of claim 36 , wherein the gas is CO.4236. The method of claim 36 , wherein the aqueous fluid is degassed water or a hydrogel.4336. The method of claim 36 , wherein the providing of the trans-cranial FUS treatment to the subject comprises placing a helmet-like head wearable claim 36 , housing a FUS transducer claim 36 , on top of the scalp ...

SYSTEMS AND METHODS FOR TREATING CANCER AND/OR AUGMENTING ORGAN FUNCTION

Systems, methods and devices for controlled sympathectomy procedures for neuromodulation in the treatment of subjects having neoplastic conditions are disclosed. Systems, methods, and devices for interventionally treating a cancerous tumor and cancer related pain are disclosed. 1. A medical system , comprising: a distal tip configured to interface with the wall of the lumen, the distal tip having one or more delivery means configured to apply a block to the target region, the distal tip having one or more dimensions configured to facilitate placement into the lumen of a target region comprising at least one of one or more nerves and one or more lymphatic ducts coupled to at least one of a tumor and a metastatic cell within a body of the subject; and', 'a controller to control operation of the one or more delivery means., 'a microsurgical tool dimensioned for insertion into a lumen with a wall, the lumen being in fluid communication with a target region of a subject, the microsurgical tool comprising2. The medical system of claim 1 , wherein the microsurgical tool further comprises one or more sensors configured to measure an extent of the block on the target region.3. The medical system of claim 2 , wherein the controller is configured to control operation of the one or more delivery means based at least in part on feedback from the one or more sensors.4. The medical system of claim 2 , wherein the one or more sensors are configured to sense neural traffic claim 2 , the microsurgical tool being configured to utilize the sensed neural traffic to locate the target region.5. The medical system of claim 1 , wherein the one or more delivery means is configured to apply the block by at least one of:isolating at least one of the tumor and the metastatic cell within the body; andaltering a growth rate of at least one of the tumor and the metastatic cell.6. The medical system of claim 1 , wherein the one or more delivery means is configured to apply the block by injecting a ...

URINARY CATHETERS, SYSTEMS AND METHODS FOR USE DURING TREATMENT OF THE PROSTATE

A urinary catheter is configured for avoiding heat buildup in, or even cooling, surrounding tissues when the prostate is subjected to treatment radiation such as ultrasound. The catheter includes a region transparent to ultrasound, and through which a cooling fluid (e.g., chilled water) may, in some embodiments, be recirculated during treatment. This region spans the prostate when the catheter is fully inserted (with the tip residing in the patient's bladder and a terminal balloon inflated to avoid retraction of the catheter). 1. A catheter configured for evacuating urine from a patient during a prostate procedure , the catheter comprising an elongated tube for insertion through the patient's urinary tract , the tube having an outer wall and a urine-evacuation lumen therethrough and comprising a plurality of adjacent regions through which the urine-evacuation lumen passes , wherein:a distal region is configured for insertion into the patient's bladder and includes a terminal urine entry port in fluid communication with the urine-evacuation lumen and an inflatable balloon for retaining the port within the bladder; andat least a prostate-spanning region, proximally adjacent to the distal region and having a length sized to span the patient's prostate gland with the balloon inflated and the urine entry port within the patient's bladder, is substantially transparent to ultrasound.2. The catheter of claim 1 , further wherein:a cooling region is coextensive with the prostate-spanning region and comprises a fluid chamber fluidically isolated from and surrounding the urine-evacuation lumen and in thermal contact with the outer wall of the catheter; anda proximal region is proximally adjacent to the cooling region, the proximal region including (i) within the outer wall of the catheter, an inlet conduit in fluid communication with the fluid chamber for conducting a fluid thereto and and outlet conduit in fluid communication with the fluid chamber for conducting a fluid ...

Ultrasonic catheter for renal denervation

Catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present technology, for example, is directed to a treatment device including a therapeutic assembly having a PVDF transducer. A method for tissue denervation through the application of ultrasonic energy, can include positioning a PVDF transducer within a blood vessel of a patient; applying RF energy to the PVDF transducer thereby causing the PVDF transducer to deliver ultrasonic energy to the tissue; and at least partially denervating tissue that is innervated by neural matter located within or in proximity to the blood vessel via the ultrasonic energy delivered to the tissue.

COMBINED SONIC AND ULTRASONIC SKIN CARE DEVICE

Dermal infusion devices and methods are provided. The device is configured to direct two different frequencies of oscillating motion (e.g., sonic and ultrasonic) towards the skin of a subject. The combination of the two different frequencies results in improved dermal infusion capabilities and can be used, for example, to effect transdermal delivery of a topical formulation. 1. A dermal infusion device , comprising:a first source of oscillatory motion, having an oscillation rate of less than 20 kHz; anda second source of oscillatory motion, having an oscillation rate of 20 kHz or greater.2. The device of claim 1 , wherein the first source has an oscillation rate of less than 1 kHz.3. The device of claim 1 , wherein the first source is selected from the group consisting of a motor claim 1 , a pneumatic device claim 1 , and a piezoelectric device.4. The device of claim 1 , wherein the second source has an oscillation rate greater than 100 kHz.5. The device of claim 1 , wherein the second source is selected from the group consisting of a piezoelectric device and a magnetostrictive device.6. The device of claim 1 , wherein the second source creates bursts of oscillatory motion with a duty cycle between 5% and 50%.7. The device of claim 1 , wherein the second source has a spatial peak claim 1 , temporal average intensity (I) of 1 W/cmor less.8. The device of claim 1 , wherein the first source has an amplitude of 0.1 inch or less.9. The device of claim 1 , wherein the first source and the second source are configured to simultaneously direct oscillatory motion to a location.10. A method of simultaneously delivering a sonic motion and an ultrasonic motion to a location claim 1 , comprising the steps of:(a) directing the sonic motion at the location from a first source of oscillatory motion, having an oscillation rate of less than 20 kHz; and(b) directing the ultrasonic motion at the location from a second source of oscillatory motion, having an oscillation rate of 20 kHz ...

METHOD FOR REDUCING BIOFILM FORMATION

A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation. 18-. (canceled)9. A medical therapeutic method comprising:removing necrotic tissue and undesired organic material from a surgical site on a patient;after the removal of all discernible necrotic tissue and undesirable organic material from the surgical site and while the surgical site is free of discernible bacteria, placing at least one ultrasonic transducer on the patient at least proximate the surgical site; andafter the placing of said transducer and while said transducer is in effective vibration-transmitting contact with the patient, conducting an electrical energization waveform of an ultrasonic frequency to said transducer at least intermittently during a period of approximately one day or longer, said waveform having frequency, amplitude and duration to effectively reduce biofilm formation on the patient at the surgical site and thereby facilitate a healing of the patient's tissue at the surgical site.10. The method defined in wherein the placing of said transducer includes removably attaching said transducer to the patient.11. The method defined in wherein the placing of said transducer includes removably attaching said transducer atop tissues at the surgical site.12. The method defined in wherein said transducer is affixed to a carrier pad claim 10 , the ...

Handpiece for the phacoemulsification of an eye lens

The invention relates to a handpiece for the phacoemulsification of an eye lens, having a needle with an aspiration line arranged therein for transporting an aspiration fluid and at least one drive element for generating a longitudinal wave, wherein the drive element is arranged in such a way that the longitudinal wave can be coupled directly into the aspiration fluid.

PORTABLE APPARATUS FOR DECONTAMINATION OF A BREAST

A portable device for the decontamination of a breast. The aim of the device is to reduce the risk of mastitis, even when the patient has a medicament incompatibility. For this purpose, the invention includes a decontamination unit which decontaminates the breast at least by means of a physical method. 1. Portable apparatus for decontamination of a breast comprising a decontamination unit which decontaminates said breast at least by way of a physical method.2. Apparatus according to claim 1 , wherein said decontamination unit comprises at least one of: a light source claim 1 , an ultrasonic source claim 1 , an ozonization source claim 1 , or a plasma source.3. Apparatus according to claim 2 , including a bell-like structure configured to be slipped over said breast and at least partially enclose said breast.4. Apparatus according to claim 3 , wherein said bell-like structure is adapted such that said breast is exposed thereto in true contour and the bell-like structure forms a recess in a region of a nipple of said breast on an inner side of the bell-like structure.5. Apparatus according to claim 4 , wherein said bell-like structure is formed such that it takes shape instantaneously only when donned onto said breast and returns to its initial state when removed from said breast.6. Apparatus according to claim 3 , wherein said decontamination unit comprises a housing in which one or more excitation radiation sources are provided claim 3 , where said housing is a separate element which is detachably mountable on said apparatus.7. Apparatus according to claim 6 , wherein said housing can be secured by being snapped onto said apparatus for decontamination of said breast at a section of a widened region which can be slipped over said breast and/or at a section of a cylindrical tube projecting from a side of said widened region facing away from said breast.8. Apparatus according to claim 6 , wherein electronics for operating said decontamination unit are connected only on ...

Medical fluid treatment machines and related systems and methods

A method comprising: receiving patient assessment information concerning one or more subjective characteristics of a patient; determining a patient assessment score based on the received patient assessment information; and modifying operation of a medical fluid treatment machine based on the patient assessment score.

Surgical cassette apparatus

A surgical cassette arrangement is provided. The arrangement includes a flow selector valve configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls irrigation and aspiration flow to the handpiece and ocular region.

Method for reducing biofilm formation

A two phase method for reducing the formation of biofilm includes an evacuation of ambient air from a region about the surgical or treatment site, to extract airborne or aerosolized bacteria ejected from the site by the treatment. The extracted bacteria are prevented from settling back onto the cleansed tissue surface, thus at least reducing colonial bacteriological growth and concomitantly exuded biofilm material. A second phase involves the attachment of one or more ultrasonic transducers to the patient over or near a surgical treatment site after the surgery is terminated. Each applied ultrasonic transducer is used to vibrate the patient's tissues at the treatment site to disrupt biofilm formation.

Systems and methods for preservation of cells

Provided herein are systems and methods for molecule delivery into cells. The method may include steps of forming a solution comprising an amount of microbubbles, an amount of soluble molecules, and one or more cells, flowing the solution through a microfluidic device, and sonicating the solution for a period of time sufficient to form pores in the one or more cells. In particular, such methods may be used for preservation of cells through delivery of a preservation agent.

Method and apparatus for treatment of intracranial hemorrhages

An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood clot in the brain, a lytic drug can be delivered to the blood clot via the fluid delivery lumens while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the fluid evacuation lumens.

Portable apparatus for decontamination of a breast

A portable device for the decontamination of a breast. The aim of the device is to reduce the risk of mastitis, even when the patient has a medicament incompatibility. For this purpose, the invention includes a decontamination unit which decontaminates the breast at least by means of a physical method.

MICROSTRUCTURE SYSTEMS AND METHODS FOR PAIN TREATMENT

The present invention relates generally to devices comprising one or more microstructures that are used to relieve, treat or prevent pain. The devices are designed such that they are inserted into the superficial layers of the skin to achieve pain relief. The devices are designed such that the microstructures are able to grasp and secure to the skin. The devices may consist of microstructures in arrays that are attached to a backing to enable the devices to adhere to the skin. Also provided are wound closure systems that comprise one or more microstructure devices along with other components, such as protective covers and therapeutics. A variety of packaging specifications are disclosed, as is a dispenser apparatus configured to enable simple one-handed application of the devices. Methods described herein provide for treatment of pain. 1. A device to reduce or prevent pain or inflammation comprising one or more microstructures.2. The device according to that reduces pain or inflammation.3. The device according to that prevents pain or inflammation.4. The device according to claim 1 , wherein at least one microstructure is capable of penetrating into tissue.5. The device according to claim 1 , wherein the one or more microstructures are contained in an array of microstructures.6. The device according to claim 5 , wherein the array or microstructures is attached to a backing.7. The device according to claim 6 , wherein the backing is in the form of a roll bandage.8. The device according to claim 1 , wherein a height of the one or more microstructures is between 100 μm and 4 mm.9. The device according to claim 1 , wherein the one or more microstructures are selected from microneedles claim 1 , microblades claim 1 , microanchors claim 1 , microfishscale claim 1 , micropillars claim 1 , and microhairs.10. The device according to claim 1 , further comprising a spring structure incorporated into the one or more microstructures.11. The device according to claim 1 , wherein ...

Flow Balancing Devices, Methods, and Systems

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described. 1. A system for regulating balanced flow of fluids , comprising:a fluid circuit with first and second fluid channels connectable to a fluid handling device, each with at least one respective pump for each of said first and second fluid channels, a controller connected to the respective pumps to control a rate of pumping of one or more of said respective pumps, the controller being connected to one or more valves to permit it to establish flows in the first and second channels;a ratio of flow rates of entering and leaving flows to and from the fluid handling device is controlled by said controller to effect a predefined net transfer of fluid to or from the fluid handling device responsively to calibration data accessible to said controller;the controller, at selected times, temporarily establishing one or more calibration flow paths in said fluid circuit, the calibration flow paths communicating respectively with ones of said first and second fluid channels to cause flow through a flow measurement component that generates a signal indicating a flow rate or relative flow rate generated by said respective pumps;the controller sampling the signal and in response to resulting samples, the controller adjusting said calibration data;the controller, using the adjusted calibration data stored in said controller to adjust the one or more of said respective pumps in order to effect said predefined net transfer of fluid to or from the fluid handling device;the selected times being determined by the controller responsively to detection ...

Flow Balancing Devices, Methods, and Systems

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

Flow Balancing Devices, Methods, and Systems

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.

SYSTEMS AND METHODS FOR DELIVERING CELLULAR AND BIOLOGICAL MATERIALS USING ULTRASOUND FOR WOUND TREATMENT AND HEALING

One embodiment is directed to a non-contact, medical ultrasound therapy system for generating and controlling low frequency ultrasound for the delivery of fluids containing biologic or cellular materials. The ultrasound therapy system includes a treatment wand including an ultrasonic transducer, a generator unit, and a cable coupling the treatment wand to the generator unit. The generator unit generates electric power output to drive the ultrasonic transducer and includes a digital frequency generator. 1. A method of treating a skin , mucosa , or other condition , the method comprising:using an ultrasound delivery device to apply to an area of skin, mucosa or other tissue affected by the condition a mist that comprises a micronized cellular or biological material.2. (canceled)3. (canceled)4. A medical ultrasound device for delivering non-contact ultrasound therapies to a skin or other condition , the device comprising:at least one treatment wand comprising an ultrasonic transducer;at least one reservoir that contains a fluid or suspension comprising a micronized cellular or biological material; anda pump that is in fluid communication with the reservoir and the treatment wand to deliver the fluid to the treatment wand such that the ultrasonic transducer atomizes the cellular or biological material as the cellular or biological material passes through the treatment wand for delivery to the wound or other tissue.5. The medical ultrasound device of claim 4 , wherein the device comprises a plurality of treatment wands and a plurality of reservoirs claim 4 , wherein each treatment wand is in fluid communication with one of the reservoirs.6. The medical ultrasound device of claim 5 , wherein at least one of the plurality of reservoirs contains a fluid for cleaning or disinfecting the area of skin or other tissue that is affected by the condition or wherein the fluid is for debriding a wound or tissue.7. (canceled)8. The medical ultrasound device of claim 5 , wherein at ...

Device for performing diagnostics and/or therapy

The disclosure relates to a device for performing diagnostics and/or therapy and related kit, system, computer program, methods and computer readable mediums. The device of this disclosure has the advantages that the device does not need access to the pericardium and that the whole system including kit and device can be removed after diagnostics/therapy. A device for performing diagnostics and/or therapy of an organ in the thoracic cavity, comprising an organ support ( 10 ), which organ support ( 10 ) is devised to be arranged exterior to an organ, and comprises: a flexible structure ( 14 ), such as a fabric, net, coil, bag or mesh, which is configured to cover a region of the organ, the region comprising at least the surface at an apex of the organ; at least one actuator ( 16 ), such as a motor, for actuating a movement of the flexible structure ( 14 ) for the therapy, and optionally at least one transducer ( 18 ), is provided.

Flow Balancing Devices, Methods, and Systems

The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described. 1. A medical treatment method , comprising:at treatment times, using peristaltic pumps, flowing medicament into and out of inflow and outflow channels connectable to a patient or treatment device;at calibration times, over a calibration interval of less than a minute, flowing medicament directly between the inflow and outflow channels such that pulsations generated by the peristaltic pumps cause pressure in a bridge channel between the inflow and outflow channels to fluctuate due to a superposition of a suction side pulsation and a pressure side pulsation of respective ones of said peristaltic pumps; andusing an adjustable flow restrictor, selecting a suction head of at least one of the respective ones of the peristaltic pumps so as to change a pulsation frequency thereof so that it differs from that of the other of the ones of the peristaltic pumps by a predetermined amount.2. The method of claim 1 , wherein the predetermined amount is such that a ratio of an inverse of a difference between pulsation frequencies of the ones of the peristaltic pumps is multiple times the calibration interval.3. The method of claim 1 , wherein the predetermined amount is such that a ratio of an inverse of a difference between pulsation frequencies of the ones of the peristaltic pumps is three times the calibration interval.4. The method of claim 1 , wherein the predetermined amount is such that a ratio of an inverse of a difference between pulsation frequencies of the ones of the peristaltic pumps is five times the calibration interval.5. The ...

THREE-DIMENSIONAL POROUS FILM CONTACT LAYER WITH IMPROVED WOUND HEALING

A wound dressing has a micro-architecture to produce appropriate strains in cells to promote the healing a wound. The apparatus includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around the wound, a vacuum source in fluid communication with the reservoir and suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound, and a porous structure positioned in contact with the wound for delivering micro-mechanical forces to localized areas of the wound. The porous structure comprises a three-dimensional film material having directional apertures formed therein. 110.-. (canceled)11. A method of treating a wound with reduced pressure , the method comprising:applying a three-dimensional film material to a wound, the three-dimensional film material having a plurality of passages defined between a male face and an opposite female face thereof, wherein the three-dimensional film material is positioned such that the male face is in contact with the wound, and wherein each of the passages includes an aperture at an apex oriented on the male face and a base oriented on the female face; andsupplying vacuum from a vacuum source in fluid communication with the three-dimensional film material to apply a negative pressure through the plurality of passages to the wound to stimulate healing of the wound.12. The method according to claim 11 , further comprising forming a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around the wound with a wound cover.13. The method according to claim 12 , wherein the reservoir comprises a wound filler.14. The method according to claim 12 , wherein vacuum is supplied through a port in communication with the wound cover.15. The method according to claim 14 , wherein vacuum is supplied through a fluid conduit in fluid communication with the ...

SYSTEMS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS

An iontophoresis system includes a preloaded reservoir containing one or more doses of a therapeutic agent. As a result, the therapeutic agent does not have to be loaded into the reservoir prior to use. In such a system, the preloaded reservoir is generally disposable. Various components of the iontophoresis system can be combined with the reservoir in a disposable cartridge that is selectively connectable to other, reusable components of the iontophoresis system. In addition, the entire iontophoresis system can be formed from one or more disposable, one-time-use modules. 1. An iontophoresis system for delivering a therapeutic agent to a subject , the iontophoresis system comprising:a support;an active electrode and an indifferent electrode configured to be connected to the support and configured to be in electrical communication with one another through a body portion of the subject, the active electrode configured to be selectively coupled to a power supply to generate a current extending through the body portion between the active electrode and the indifferent electrode;a controller configured to be operatively connected to the active electrode and the power supply to control an amount of power transmitted from the power supply to the active electrode to generate the current through the body portion;a reservoir preloaded with a therapeutic agent and configured to be connected to the support in operative alignment with the active electrode for delivering the therapeutic agent from an outlet of the reservoir into the body portion of the subject using an electromotive force of the current passing through the body portion; anda removable cover covering at least the outlet of the reservoir to contain the therapeutic agent within the reservoir until the covering is removed from the outlet.2. An iontophoresis system as set forth in claim 1 , wherein the support has a distal end claim 1 , the reservoir being attachable to the support to extend to the distal end thereof.3 ...

Combined sonic and iontophoretic skin care device

The present disclosure seeks to address the primary problem of long application durations to deliver an effective dose of an active ingredient. The devices combine mechanical motion with electrically induced flux (e.g., iontophoresis). The combination of techniques in a single device can reduce the treatment time required to deliver the active ingredient in an effective dose, or deliver a larger dose over the same duration of application.

Blood treatment and electrical blood leak detection device therefore

A blood treatment machine includes a blood pump; an arterial line in fluid communication with the blood pump, the arterial line including an arterial needle; a venous line including a venous needle; and a blood leak detection device including (i) at least one electrical component, (ii) a member configured to secure the at least one electrical component onto a patient's arm adjacent to patient access of at least one of the arterial and venous needles, the at least one electrical component capable of sensing the presence of a blood leak, and (iii) a controller in operable communication with the at least one electrical component, the controller programmed to allow for an amount of expected blood seepage and to cause an alarm if blood greater than the amount of expected blood seepage is sensed by the at least one electrical component.

TISSUE TREATMENT DEVICE

Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, a therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

VENTILATION MACHINE AND METHOD OF VENTILATING A PATIENT

A ventilation machine is disclosed that includes a conduit interface configured to be connected to a respiratory system of a human or animal patient, an air flow generator configured to deliver air through the conduit interface into the respiratory system of the patient, a processing unit in communication with the air flow generator and configured to control the airflow generator to deliver air into the respiratory system of the patient according to a breathing scheme, and an induction device for activating a diaphragm of the patient. The induction device is in communication with the processing unit. The processing unit is configured to control the induction device to activate the diaphragm in coordination with the breathing scheme. 178-. (canceled)79. A ventilation machine , preferably being a single assembly , comprising:a conduit interface configured to be connected to a respiratory system of a human or animal patient;an air flow generator configured to deliver air through the conduit interface into the respiratory system of the patient;a processing unit in communication with the air flow generator and configured to control the airflow generator to deliver air into the respiratory system of the patient according to a breathing scheme; and the induction device is in communication with the processing unit, and', 'the processing unit is configured to control the induction device to activate the diaphragm in coordination with the breathing scheme., 'an induction device, preferably an electro-magnetic induction device, for activating a diaphragm of the patient, wherein'}80. The ventilation machine of claim 79 , wherein the processing unit comprises an input interface and the processing unit is configured such that the breathing scheme can be inputted via the input interface.81. The ventilation machine of claim 79 , wherein the breathing scheme comprises a time gap between start of operation of the induction device and start of operation of the air flow generator.82. ...

WOUND TREATMENT APPARATUS AND METHOD

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus. 145.-. (canceled)46. A wound dressing comprising:a wound cover configured to be placed over a wound;a manifold configured to be disposed between the wound cover and the wound, the manifold configured to conform to the shape of the wound, the manifold comprising a plurality of flow channels configured to aspirate fluid from the wound;an outlet tube configured to fluidically couple the manifold to a negative pressure source; andan ultrasonic transducer configured to be disposed in the wound under the wound cover, the ultrasonic transducer configured to apply a vibrational energy to the wound.47. The dressing of claim 46 , further comprising an inlet tube configured to fluidically couple the manifold to a fluid source claim 46 , wherein the manifold further comprises a plurality of apertures configured to deliver fluid to the wound.48. The dressing of claim 47 , further comprising a wound contact layer configured to be positioned in direct contact with the wound and further configured to conform to the shape of the wound claim 47 , the wound contact layer comprising a plurality of apertures configured to allow fluid to pass through the wound contact layer.49. The dressing of claim 46 , wherein the ultrasonic transducer is configured to apply the vibrational ...

SYSTEMS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS

An iontophoresis system includes a preloaded reservoir containing one or more doses of a therapeutic agent. As a result, the therapeutic agent does not have to be loaded into the reservoir prior to use. In such a system, the preloaded reservoir is generally disposable. Various components of the iontophoresis system can be combined with the reservoir in a disposable cartridge that is selectively connectable to other, reusable components of the iontophoresis system. In addition, the entire iontophoresis system can be formed from one or more disposable, one-time-use modules. 1. An iontophoresis system for delivering a therapeutic agent to a subject , the iontophoresis system comprising:a support;an active electrode and an indifferent electrode configured to be connected to the support and configured to be in electrical communication with one another through a body portion of the subject, the active electrode configured to be selectively coupled to a power supply to generate a current extending through the body portion between the active electrode and the indifferent electrode;a controller configured to be operatively connected to the active electrode and the power supply to control an amount of power transmitted from the power supply to the active electrode to generate the current through the body portion;a reservoir preloaded with a therapeutic agent and configured to be connected to the support in operative alignment with the active electrode for delivering the therapeutic agent from an outlet of the reservoir into the body portion of the subject using an electromotive force of the current passing through the body portion; anda removable cover covering at least the outlet of the reservoir to contain the therapeutic agent within the reservoir until the covering is removed from the outlet.2. An iontophoresis system as set forth in claim 1 , wherein the support has a distal end claim 1 , the reservoir being attachable to the support to extend to the distal end thereof.3 ...

SYSTEMS AND METHODS FOR OPENING OF A TISSUE BARRIER

Systems and methods for opening a tissue to a target value using microbubbles are disclosed herein. In an embodiment of a method for opening a tissue to a target value using microbubbles, a region of the tissue is targeted for opening, an acoustic parameter corresponding to the target value is determined, and an ultrasound beam is applied to the target region at the acoustic parameter such that the tissue at the target region is opened to the target value with the microbubbles. The acoustic parameter can be selected to control an acoustic cavitation event and, in some embodiments, controlling an acoustic cavitation event can include controlling a location, number and/or magnitude of acoustic cavitation events. 1. A method for opening a tissue to a target value using microbubbles , comprising:targeting a region of the tissue to open;determining at least one acoustic parameter corresponding to the target value, the at least one acoustic parameter is selected to control one or more acoustic cavitation events to open the tissue to the target value to thereby allow passage of molecules and/or agents; andapplying an ultrasound beam at the at least one acoustic parameter to the targeted region such that the tissue is opened with the microbubbles to the target value.2. The method of claim 1 , further comprising positioning the microbubbles in proximity to the targeted region claim 1 , wherein positioning the microbubbles comprises performing at least one injection of the microbubbles such that the microbubbles are positioned proximate to the targeted region.3. The method of claim 2 , further comprising determining at least one of a number of injections of the microbubbles corresponding to the target value and a duration of injection of the microbubbles corresponding to the target value.4. The method of claim 2 , wherein the at least one injection comprises at least one of a systemic injection claim 2 , a bolus injection and a slow diffusion injection.5. The method of claim ...

Method and system for imaging

A method for dynamic investigation of a subject lung, the method comprising the steps of: (i) imparting an oscillation to the lung at one or more forcing frequencies so as to elicit a lung response, (ii) sensing the response of the lung simultaneously with the imparting of the oscillation to elicit a lung response, (iii) choosing at least one parameter used in the sensing to define the lung motion associated with the lung response, (iv) comparing one of the chosen parameters at each forcing frequency with the response at the forcing frequency in at least one region of the lung, and (v) recording the comparison of step (iv).

SYSTEM FOR REDUCING LOCAL DISCOMFORT

A device for targeted delivery of a substance to an airway may include a conduit and at least two applicators. The conduit may include a primal end and a bifurcated distal portion having two distal ends. Each applicator may be coupled with one of the distill ends of the conduit and may be configured to direct the substance out of the applicator toward one of two sides of an airway. A method for targeted delivery of a substance to an airway may involve advancing a substance delivery device into the airway, contacting two sides of the airway with at least two applicators of the substance delivery device, such that each applicator contacts the airway near a glossopharyngeal nerve and/or a superior laryngeal nerve on each of the two sides of the airway, and delivering the substance through the applicators to contact the airway along the two sides. 1. A device for targeted delivery of a substance to an airway of a patient , the device comprising:a conduit comprising a proximal end and a distal portion having at least one distal end, wherein the proximal end is configured to be coupled with a source of the substance provided via a mechanical pump; andat least one applicator coupled with the at least one distal end of the conduit, wherein the at least one applicator is configured to direct the substance out of the applicator toward a portion of the airway of the patient.2. A device as in claim 1 , wherein the conduit is configured to removably attach to an endotracheal tube.3. A device as in claim 1 , wherein the conduit is configured to removably attach to an laryngeal mask airway.4. A device as in claim 1 , wherein the conduit is configured to rest against one or more portions of the patient's mouth.5. A device as in claim 4 , wherein the one or more portions of the patient's mouth comprise the patient's teeth.6. A device as in claim 1 , wherein the device is configured to be advanced into the airway and used for substance delivery without requiring attachment to any ...

BRAIN STIMULATION SYSTEM, METHOD AND APPARATUS BASED ON ARTIFICIAL INTELLIGENCE AND STORAGE MEDIUM

Provided are a brain stimulation system, method, apparatus and storage medium based on artificial intelligence. The system includes: a plurality of brain stimulation terminals and a cloud platform. The cloud platform is configured to, with artificial intelligence algorithm especially machine learning and deep learning, generate multi-dimensional psychological big data using physiological data and psychological state evaluation parameters gotten from the plurality of brain stimulation terminals and established models of algorithm for disease diagnosis. The brain stimulation terminal is configured to analyze the physiological data and psychological state evaluation parameters of a target subject, measure a mental state of the target subject, obtain brain stimulation parameters required for the target subject according to the mental state, and generate corresponding non-invasive brain stimulation for the target subject according to the brain stimulation parameters based on the multi-dimensional big data through the artificial intelligence algorithm. 1. A brain stimulation system based on artificial intelligence , comprising: a plurality of brain stimulation terminals and a cloud platform in communication connection with the plurality of brain stimulation terminals ,wherein the cloud platform is configured to, with artificial intelligence algorithm, generate multi-dimensional psychological big data using physiological data and psychological state evaluation parameters gotten from the plurality of brain stimulation terminals and established models of algorithm for brain disease diagnosis and evaluation ;wherein each of the plurality of brain stimulation terminals is configured to: analyze collected physiological data and psychological state evaluation parameters of a target subject based on algorithm from multi-dimensional psychological big data and involved the artificial intelligence algorithm, measure a mental state of the target subject, obtain brain stimulation ...

Acoustic access disconnection systems and methods

An access disconnection system includes: an arterial line; a venous line; a transmitter configured to transmit a sound wave in one of the arterial and venous lines when connected to a patient; a receiver configured to receive the sound wave from the other of the arterial and venous lines when connected to the patient; and electronic circuitry coupled to at least one of the transmitter and receiver, the circuitry configured to send a disconnection output indicative of a change in the sound waves received by the receiver from the transmitter sufficient to expect that an access disconnection of one of the arterial line and venous lines has occurred.

Method of treating wounds by creating a therapeutic solution with ultrasonic waves

A method of treating areas of the body utilizing ultrasonic vibrations to mix different materials together as to create a therapeutic combination is disclosed. The materials are mixed by passing them through an ultrasound horn vibrating in resonance, having an internal chamber. As the materials pass through the internal chamber, ultrasonic vibrations emanating from and/or echoing off the various walls of the chamber mix the materials into a potentially therapeutic combination. Ultrasonic vibrations emanating from the radiation surface of the horn may be used to spray the created therapeutic combination onto the area of the body to be treated.

Three-dimensional porous film contact layer with improved wound healing

A wound dressing has a micro-architecture to produce appropriate strains in cells to promote the healing a wound. The apparatus includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around the wound, a vacuum source in fluid communication with the reservoir and suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound, and a porous structure positioned in contact with the wound for delivering micro-mechanical forces to localized areas of the wound. The porous structure comprises a three-dimensional film material having directional apertures formed therein.

Surgical cassette apparatus

A surgical cassette arrangement is provided. The arrangement includes a flow selector valve configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls irrigation and aspiration flow to the handpiece and ocular region.

Surgical cassette apparatus

A surgical cassette arrangement is provided. The arrangement includes a flow selector valve configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls irrigation and aspiration flow to the handpiece and ocular region.

Surgical cassette apparatus

A surgical cassette arrangement is provided. The arrangement includes a flow selector valve configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls irrigation and aspiration flow to the handpiece and ocular region.

Liposuction devices and methods and surrounding aspiration systems and methods

Liposuction devices and methods and surrounding aspiration systems and methods that reduce the chances of burning and necrosis. The devices include an evacuation tube surrounding an ultrasonic probe, including the distal end thereof to define a liquefaction and/or rupture chamber. The evacuation tube has one or more openings in the distal end through which tissue such as fatty tissue may enter for rupture/liquefaction therein. Containing the ultrasonic probe within the evacuation tube avoids any possible contact with surrounding tissue other than tissue that gets drawn into the liquefaction and/or rupture chamber. The size of the liquefaction and/or rupture chamber may be variable by adjustment of the axial position of the evacuation tube relative to the ultrasonic probe, or by selection of evacuation tubes of the desired length. Various embodiments are disclosed.

Surgical cassette apparatus

A surgical cassette arrangement is provided. The arrangement includes a flow selector valve (202) configured to operate with a handpiece to selectively irrigate and aspirate fluid with respect to an ocular region. The flow selector valve includes at least three ports, with one port fluidly connectable to the handpiece. The arrangement further includes a reservoir (204) fluidly connected to a second port of the flow selector valve via a first flow segment and configured to receive fluid from the flow selector valve, and a collector (206) fluidly connected to a third port of the flow selector valve via a second flow segment and configured to receive fluid from the flow selector valve and from the reservoir. The flow selector valve selectively controls irrigation and aspiration flow to the handpiece and ocular region.

Injection system for delivering multiple fluids within the anatomy

Devices and systems for injecting fluids and/or other materials into a targeted anatomical location, in particular, a joint or intra-articular space, include a handpiece assembly having a needle extending from its distal end, a fluid delivery module comprising a cassette and a fluid transfer device. A conduit is generally configured to place the fluid delivery module in fluid communication with the handpiece assembly. Medicaments, formulations and/or other fluids or materials contained within vials that are secured to a cassette or other portion of the fluid delivery module can be selectively delivered into an anatomy through a needle located at the distal end of the handpiece assembly. In some embodiments, ultrasound or other imaging technologies can be used to locate a joint or other targeted anatomical location.

吸脂装置和方法以及环绕抽取系统和方法

减少烧伤和坏死可能性的吸脂装置和方法以及环绕抽取系统和方法。该装置包括围绕着超声探针的抽吸管，它含有用来限定液化和/或破裂腔的末梢端部。该抽吸管在末梢端部内具有一个或多个孔，例如脂肪组织之类的组织能通过该孔进入以便在里面破裂/液化。将超声探针包含在该抽吸管内部能避免与除了要吸入液化和/或破裂腔的组织以外的周围组织的任何可能接触。液化和/或破裂腔的大小可以改变，其方法为，调节抽吸管相对于超声探针的轴向位置，或者选择所需长度的抽吸管。披露了各种各样的实施例。

Portable apparatus for breast disinfection

FIELD: medicine; hygiene. SUBSTANCE: group of inventions relates to medical equipment, specifically to a portable apparatus for disinfection of the breast and a method for disinfecting the breast. For this purpose, the apparatus according to the invention comprises a disinfecting device which provides disinfection of the breast by, at least, a physical method. EFFECT: use of this apparatus reduces the risk of mastitis even in patients who are characterized by intolerance to medicines. 17 cl, 11 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 719 012 C1 (51) МПК A61N 5/06 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК A61N 5/06 (2020.01) (21)(22) Заявка: 2019104400, 09.08.2017 (24) Дата начала отсчета срока действия патента: Дата регистрации: 16.04.2020 09.08.2016 EP 16183310.8 (73) Патентообладатель(и): КАРАГ АГ (CH) (45) Опубликовано: 16.04.2020 Бюл. № 11 (56) Список документов, цитированных в отчете о поиске: WO 2006037599 A1, 13.04.2006. US 2008106896 A1, 08.05.2008. WO 2011144344 A2, 24.11.2011. CN 201046247 Y, 16.04.2008. RU 2549325 C1, 27.04.2015. (85) Дата начала рассмотрения заявки PCT на национальной фазе: 11.03.2019 (86) Заявка PCT: WO 2018/029280 (15.02.2018) Адрес для переписки: 197101, Санкт-Петербург, а/я 128, "АРСПАТЕНТ", М.В. Хмара (54) ПОРТАТИВНЫЙ АППАРАТ ДЛЯ ДЕЗИНФЕКЦИИ ГРУДИ (57) Реферат: Группа изобретений относится к медицинской непереносимость к медикаментам. С этой целью технике, а именно к портативному аппарату для аппарат согласно изобретению содержит дезинфекции груди и способу дезинфекции груди. дезинфицирующее устройство, обеспечивающее Применение этого аппарата снижает риск мастита дезинфекцию груди по меньшей мере посредством даже у пациенток, которым свойственна физического метода. 4 н. и 13 з.п. ф-лы, 11 ил. R U 2 7 1 9 0 1 2 (87) Публикация заявки PCT: C 1 C 1 EP 2017/070250 (09.08.2017) 2 7 1 9 0 1 2 Приоритет(ы): (30) Конвенционный приоритет: R U 09.08.2017 (72) Автор(ы): ...

Apparatus For Complex Medical Procedure

본 고안은 초음파시술과 음압시술을 동시에 시행할 수 있게 하는 부항기 형태의 복합 시술기에 관한 것이다. 그의 구성은; 바닥판(11)과 측벽(12)으로 구성되는 컵형태의 본체(10); 상기 본체(10)의 바닥판(11)을 관통하여 설치되되 상기 바닥판(11)에 지지됨으로써 상기 본체(10)의 내부공간에 설치되는 초음파진동자(20); 상기 본체(10)의 내부공간(S)의 공기를 빼냄으로써 상기 본체(10)가 신체에 밀착되었을 경우 상기 내부공간(S)에 음압이 조성되도록 하기 위한 음압발생부(30);를 포함하는 것을 특징으로 한다. The present invention relates to a cupping machine-type combined procedure that can be performed at the same time ultrasound and sound pressure procedures. Its composition is; A cup-shaped body 10 composed of a bottom plate 11 and side walls 12; An ultrasonic vibrator 20 installed through the bottom plate 11 of the main body 10 and supported by the bottom plate 11 to be installed in the inner space of the main body 10; A negative pressure generating unit 30 for extracting air in the internal space S of the main body 10 so that a negative pressure is formed in the internal space S when the main body 10 is in close contact with the body; It is characterized by.

Method and device for drug delivery

FIELD: medicine. SUBSTANCE: invention refers to medical equipment, namely to devices for drug delivery to a patient, particularly to devices for subcutaneous drug or substance delivery, and using energy sources for providing more effective introduction of drugs. The device for therapeutic substance delivery to a patient's body comprises an infusion catheter, a catheter attachment element, a case, a therapeutic element and a controller. The infusion catheter is presented to be introduced into body tissue at an introduction area on a patient's body and to deliver the therapeutic substance into the patient's body within the infusion area. The infusion area covers a body tissue volume surrounding the introduction area. The catheter attachment element is presented to be attached to patient's skin and to attach the infusion catheter to skin. The case comprises the device for drug delivery designed for introducing the therapeutic substance into the infusion catheter for delivering the therapeutic substance within the infusion area, and a sensor integrated in the case and detecting the infusion of the therapeutic substance. The therapeutic element is presented to apply the therapy close to the infusion area for changing pharmacokinetic and/or pharmacodynamic profile of the therapeutic substance. The controller is presented to enable data exchange with the therapeutic element and to begin the therapy with the therapeutic element after the beginning of the infusion of the therapeutic substance has been found. EFFECT: invention provides effective and well-timed insulin delivery into blood thereby preventing or reducing hyperglycemic and hypoglycemic attacks. 21 cl, 50 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 477 151 (13) C2 (51) МПК A61M 5/142 A61M 5/158 A61M 5/168 A61M 5/172 A61M 25/01 (2006.01) (2006.01) (2006.01) (2006.01) (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2009135624/14, 19.03. ...

Acoustic access disconnection systems and methods

【課題】本発明は、本明細書に記載されたアクセス切断システムを提供する。【解決手段】アクセス切断システムは、動脈管路（１４）と、静脈管路（１８）と、患者（１２）に接続されるときに、動脈（１４）および静脈管路（１８）の一方において音波を伝達するように構成されるトランスミッタ（６２）と、患者（１２）に接続されるときに動脈（１４）および静脈管路（１８）の他方から音波を受信するように構成されるレシーバ（６４）と、トランスミッタおよびレシーバのうちの少なくとも一方に結合される電子回路（６６）であって、動脈管路（１４）および静脈管路（１８）の一方のアクセス切断が既に発生したことを予期するのに十分な、レシーバ（６４）によって受信されるトランスミッタ（６２）からの音波における変化を示す切断出力を送信するように構成される、電子回路（６６）とを含む。【選択図】図７

Ultrasound device for facilitating waste clearance of the brain lymphatic system

The present invention relates to an ultrasound device, and more particularly, to an ultrasound device for promoting the waste clearance from the brain lymphatic system. To this end, the ultrasound device comprises: a first frequency generator (210) for generating a predetermined frequency; a first waveform modulator (230) for modulating a waveform of a frequency; a first linear amplifier (250) for amplifying the waveform; a first resonance circuit unit (170a) for matching the impedance of the amplified waveform; and a first transducer (100) connected to the first resonance circuit unit (170a) and irradiating an ultrasound (30) toward the mammalian brain (10). Provided is the ultrasound device for promoting the waste clearance from the brain lymphatic system, characterized in that the ultrasound (30) promotes the waste clearance from the brain lymphatic system (10). The ultrasound passing through the skull of a mammal is irradiated into the deep brain to induce volume flow by dynamic pressure.

Wound treatment apparatus and method

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus.

Wound treatment apparatus and method

An apparatus for cleansing wounds in which irrigant fluid from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are moved by a device (which may be a single pump or two pumps) for moving fluid through a flow path which passes through the dressing and a means for providing simultaneous aspiration and irrigation of the wound. The apparatus also comprises means to apply high frequency vibrational energy, e.g. ultrasound, to the wound bed. The former removes materials deleterious to wound healing, while distributing materials that are beneficial in promoting wound healing over the wound bed. The latter promotes healing. The dressing and a method of treatment using the apparatus.

Three-dimensional porous film contact layer with improved wound healing

A wound dressing has a micro-architecture to produce appropriate strains in cells to promote the healing a wound. The apparatus includes a wound cover for defining a reservoir over a wound in which a negative pressure may be maintained by forming a substantially fluid-tight seal around the wound, a vacuum source in fluid communication with the reservoir and suitable for providing an appropriate negative pressure to the reservoir to stimulate healing of the wound, and a porous structure positioned in contact with the wound for delivering micro-mechanical forces to localized areas of the wound. The porous structure comprises a three-dimensional film material having directional apertures formed therein.

wound treatment system, wound treatment system for surgically cleaning and healing a wound site, ultrasonic wound treatment system for treating a wound site, method for treating a wound, multipurpose wound bandage and multipurpose wound dressing bandage

SISTEMA DE TRATAMENTO DE FERIDA, SISTEMA DE TRATAMENTO DE FERIDA PARA LIMPAR CIRURGICAMENTE E CURAR UM SìTIO DE FERIDA, SISTEMA DE TRATAMENTO ULTRA-SONICO DE FERIDA PARA TRATAR UM SITIO DE FERIDA, MéTODO PARA O TRATAMENTO DE UMA FERIDA, BANDAGEM DE FERIDA DE MULTIPLOS PROPóSITOS E BANDAGEM DE LIMPEZA DE FERIDA DE MúLTIPLOS PROPóS ITOS Trata-se de um sistema de tratamento de ferida que inclui uma unidade de distribuição, uma fonte de pressão reduzida, uma fonte de distribuição de fluido, e um transdutor de energia ultra-sónica. A pressão reduzida e a distribuição de fluido podem ser aplicadas à ferida através da unidade de distribuição. O transdutor de energia ultra- sónica é configurado para aplicar a energia ultra-sónica à ferida para limpar cirurgicamente a ferida. O transdutor de energia ultra-sónica pode ser um transdutor piezelétrico ou um dispositivo de onda acústica de superfície. O transdutor de energia ultra-sónica pode ser colocado adjacente à unidade de distribuição para aplicar a energia ultra-sónica diretamente à ferida ou pode ser acoplado a uma membrana acusticamente condutora posicionada entre a unidade de distribuição e a ferida. Wound treatment system, wound treatment system to surgically clean and cure a wound site, ultrasonic wound treatment system to treat a wound site, a wound treatment method AND MULTIPLE PURPOSE WOUND CLEANING BANDING This is a wound treatment system that includes a dispensing unit, a reduced pressure source, a fluid dispensing source, and an ultrasonic energy transducer. Reduced pressure and fluid delivery can be applied to the wound through the delivery unit. The ultrasonic energy transducer is configured to apply ultrasonic energy to the wound to surgically clean the wound. The ultrasonic energy transducer may be a piezoelectric transducer or a surface acoustic wave device. The ultrasonic energy transducer may be placed adjacent to the delivery unit to apply ultrasonic energy directly to the wound or may be coupled to an ...

Device and method for drug delivery to a targeted skin layer

The present invention relates to a device and method for the controlled delivery of a drug to a targeted layer of the skin in a human or animal subject. In particular, the present invention relates to such a device, system and method for selective drug delivery to the cutaneous or subcutaneous layer of skin to enhances the effectiveness of the drug delivery.

System and method for treating a wound using ultrasonic debridement

A wound treatment system includes a distribution manifold, a reduced pressure source, a fluid delivery source, and an ultrasonic energy transducer. Reduced pressure and fluid delivery may be applied to the wound through the distribution manifold. The ultrasonic energy transducer is configured to deliver ultrasonic energy to the wound to debride the wound. The ultrasonic energy transducer may be either a piezoelectric transducer or a surface acoustic wave device. The ultrasonic energy transducer may be placed adjacent to the distribution manifold to deliver ultrasonic energy directly to the wound or may be coupled to an acoustically-conducting membrane positioned between the distribution manifold and the wound.

Tissue treatment device

Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, a therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

Tissue treatment device

Disclosed embodiments relate to apparatuses and methods for wound treatment with ultrasound. In certain embodiments, a therapeutic ultrasound wound treatment apparatus includes a wound dressing configured to be positioned over a wound to provide a substantially fluid impermeable seal over the wound and a transducer to deliver therapeutic ultrasound to tissue. The therapeutic ultrasound wound treatment apparatus may further include a wound contact layer configured to be positioned in contact with the wound, a transmission layer positioned above the wound contact layer, an absorbent layer positioned above the transmission layer and configured to absorb wound fluid, and a backing layer positioned above the absorbent layer and including an orifice. Also disclosed are multiple parameters for the therapeutic ultrasound signal.

System and method for treating a wound using ultrasonic debridement

A wound treatment system includes a distribution manifold, a reduced pressure source, a fluid delivery source, and an ultrasonic energy transducer. Reduced pressure and fluid delivery may be applied to the wound through the distribution manifold. The ultrasonic energy transducer is configured to deliver ultrasonic energy to the wound to debride the wound. The ultrasonic energy transducer may be either a piezoelectric transducer or a. surface acoustic wave device. The ultrasonic energy transducer may be placed adjacent to the distribution manifold to deliver ultrasonic energy directly to the wound or may be coupled to an acoustically-conducting membrane positioned between the distribution manifold and the wound.

Method and device for drug delivery

A method and a device for a delivery of a chemical substance to the body of the patient are provided. The device includes an infusion catheter configured to be inserted into a tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.

Drug delivery device

Method and device for drug delivery

Systems, devices and methods for delivery of a chemical substance to the body of the patient are provided. Such embodiments may include an infusion catheter configured to be inserted into tissue, a catheter securing element configured to be adhered to the skin of the patient and further configured to secure the infusion catheter to the skin, a drug delivery pump configured to infuse a drug into the infusion catheter for delivery to a drug infused region on the body of the patient, and a treatment element configured to apply a treatment to the drug infused region to improve pharmacodynamics of the drug during a period of delivery of the drug to the patient.

Method and device for drug delivery

FIELD: medicine. SUBSTANCE: device comprises a therapeutic element incuding a portion through which the injection is performed into the tissue using a catheter or a syringe. The therapeutic element is adapted to provide therapy near the injection site to alter the pharmacokinetic and/or pharmacodynamic profile of the injectate. The said therapy may be a temperature change, optical radiation, electromagnetic radiation, mechanical vibration, etc. The device also includes a sensor configured to detect therapeutic substance injection, and a controller configured to communicate with the therapeutic component and to start therapy when the sensor detects the start of substance injection. EFFECT: device provides predetermined therapeutic agent delivery to the patient by controlling the pharmacokinetic and/or pharmacodynamic profile of injectate. 18 cl, 50 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (51) МПК A61M 5/142 A61M 5/158 A61M 5/168 A61M 5/172 A61M 25/01 (11) (13) 2 618 952 C2 (2006.01) (2006.01) (2006.01) (2006.01) (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ФОРМУЛА (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ 2012151965, 19.03.2008 (24) Дата начала отсчета срока действия патента: 19.03.2008 Дата регистрации: (73) Патентообладатель(и): Инсьюлин Медикал Лтд. (IL) (56) Список документов, цитированных в отчете о поиске: US 2002/040208 A1, 04.04.2002. SU 211733 A1, 19.02.1968. RU 2147893 C1, 27.04.2000. US 2003/0130616 A1, 10.07.2003. WO 00/32259 A, 08.06.2000. FR 2795629 A, 05.01.2001. НИКОНОВ А. В. Способ и универсальное устройство для суперселективной катетеризации сосудов с дистанционным управлением. Юбилейный сбрник научных работ по невропатологии и (см. прод.) (43) Дата публикации заявки: 10.06.2014 Бюл. № 16 R U 2 6 1 8 9 5 2 (45) Опубликовано: 11.05.2017 Бюл. № 14 Адрес для переписки: 191036, Санкт-Петербург, а/я 24, "НЕВИНПАТ" (54) Способ и устройство для доставки лекарственных средств (57) Формула изобретения 1. Терапевтическое ...

A kind of equipment for performing diagnosis and/or treatment

本发明涉及一种用于执行诊断和/或治疗的设备及相关的套件、系统、计算机程序、方法和计算机可读介质。本发明的设备具有如下优点：它不需要进入心包，并且包括套件和设备的整个系统可在诊断/治疗之后移除。本申请提供了一种用于对胸腔内器官执行诊断和/或者治疗的设备，包括器官支撑件(10)，该器官支撑件被设置在器官外部，并且包括诸如例如织物、网、线圈、袋子或者网眼的柔性结构(14)。该柔性结构被配置为覆盖所述器官的这样的区域，该区域包括至少处于所述器官顶点的表面；至少一个诸如电机的致动器(16)，其用于驱使柔性结构(14)移动以实现治疗；以及可选地至少一个换能器(18)。

Liposuction device and method and enclosed suction system and method

An Apparatus for Caring a Skin with a Ultrasound Wave and an Iontophoresis and a Method for Caring the Skin Using the Same

본 발명은 초음파 및 이온토포레시스 방식의 피부 미용 장치 및 그에 의한 피부 미용 방법에 관한 것이다. 초음파 및 이온토포레시스 방식의 피부 미용 장치는 서로 다른 주파수 대역의 초음파를 발생시키는 초음파 모듈(12); 피부 접촉 영역으로 가변 크기를 가지는 전류를 유도하는 이온토포레시스 모듈(13); 발생된 초음파 및 전류가 피부에 인가되도록 제어하는 제어 모듈(11); 및 발생된 초음파 및 가변 전류를 피부에 인가하는 접촉 인가 모듈(15)을 포함한다.

Liposuction devices and methods and surrounding aspiration systems and methods

본 발명은 지방 흡입 장치 및 방법과 서라운딩 흡인 시스템 및 방법은 화상 및 탈저 현상이 생길 수 있는 기회를 감소시킨다. 상기 장치는 액화 및/또는 파열 챔버를 형성하는 원단부를 포함하는, 초음파 프로브를 둘러싸는 추출 튜브를 포함한다. 추출 튜브는 원단부에 하나 이상의 개구를 갖고, 이 개구를 통하여 지방 조직 등의 조직이 파열/액화되도록 상기 추출 튜브 내로 들어갈 수 있다. 추출 튜브 내에 초음파 프로브를 포함시킴으로써 액화 및/또는 파열 챔버 내로 들어간 조직이 아닌 주위 조직과 접촉될 수 있는 가능성이 방지된다. 액화 및/또는 파열 챔버의 치수는 추출 튜브의 위치를 초음파 프로브에 대하여 조정하거나, 또는 원하는 길이의 추출 튜브를 선택함으로써 변경시킬 수 있다. 여러 가지 실시예를 기재한다. 지방 흡입 장치, 서라운딩 흡인 시스템, 액화 및/또는 파열 챔버, 초음파 프로브, 추출 튜브. The present invention provides a liposuction apparatus and method and a surround suction system and method to reduce the chance of burns and degassing. The device includes an extraction tube surrounding the ultrasonic probe, including a distal portion forming a liquefaction and / or rupture chamber. The extraction tube has one or more openings in the distal end, through which openings may be introduced into the extraction tube such that tissue such as adipose tissue may rupture / liquefy. The inclusion of an ultrasonic probe in the extraction tube prevents the possibility of contacting with surrounding tissue rather than tissue that has entered the liquefaction and / or rupture chamber. The dimensions of the liquefaction and / or rupture chamber can be altered by adjusting the position of the extraction tube relative to the ultrasonic probe or by selecting an extraction tube of the desired length. Various examples are described. Liposuction device, surround suction system, liquefaction and / or rupture chamber, ultrasonic probe, extraction tube.

Wound removing apparatus using ultra-sonic wave

본 발명은 초음파 창상제거기에 관한 것으로서, 보다 상세하게는 초음파 에너지를 이용하여 창상 제거 약품을 창상에 효율적으로 전달하고, 치료기의 사용시 병균에 의한 오염이 발생될 수 있는 치료기의 구성 부위를 효과적으로 교체할 수 있도록 하고, 창상 제거에 사용되는 치료용 액체의 공급과 배출이 효과적으로 이루어지도록 하는 초음파 창상제거기에 관한 것이다. 본 발명에 따르면 창상치료에 사용되는 수단의 사용중에 액체를 원활하게 치료 부위에 정확하게 공급할 수 있으며, 치료와 동시에 액체 및 탈락된 조직을 신속하게 배출할 수 있는 효과가 있다. The present invention relates to an ultrasonic wound remover, and more particularly, effectively delivers a wound removal drug to the wound using ultrasonic energy, and effectively replaces a component part of a treatment device that may cause contamination by pathogens when using the treatment device. The present invention relates to an ultrasonic wound remover for effectively supplying and discharging a therapeutic liquid used for wound removal. According to the present invention, the liquid can be smoothly and accurately supplied to the treatment area during the use of the means used for wound treatment, and there is an effect of rapidly discharging the liquid and the removed tissue simultaneously with the treatment.

Flow balancing methods