ПЕРФУЗИОННЫЙ БАЛЛОН С ВНЕШНИМ КЛАПАНОМ

СПОСОБЫ И АППАРАТ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ УХА, ГОРЛА, НОСА

... 1. Устройство для расширения устья околоносовой пазухи человека или животного, содержащее: ! рукоятку; ! вытянутый ствол, имеющий проксимальный конец, соединенный с рукояткой, и дистальный конец, причем ствол имеет просвет и продольное отверстие, проходящее от просвета к внешней поверхности ствола вдоль по меньшей мере части длины между проксимальным и дистальным концами; ! проволочный направитель, проходящий через по меньшей мере часть просвета ствола; ! расширитель, имеющий нерасширенную конфигурацию и расширенную конфигурацию, причем по меньшей мере часть расширителя размещена на проволочном направителе и внутри просвета ствола; и ! скользящий элемент, соединенный с проволочным направителем и (или) расширителем через продольное отверстие ствола для продвижения проволочного направителя и (или) расширителя относительно ствола. ! 2. Устройство по п.1, в котором дистальный конец вытянутого ствола содержит вытянутый трубчатый элемент, соединенный с вытянутым стволом. ! 3. Устройство по п.1 ...

Ballonkatheter

KATHETER ZUR UNTERSUCHUNG ODER BEHANDLUNG EINES BLUTGEFAESSES

Self-inflating medical apparatus

BALLONOKKLUSIONSVORRICHTUNG WITH A PROXIMAL VALVE

DEVICE FOR INJECTING A FLUID AND AN ENLARGEMENT PROBE FOR IMPLANTIEREN INTO BODY CAVITIES

Intragastric device

Abstract Devices and methods for treating obesity are provided. More particularly, intragastric devices and devices for inflating and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. Fig 8B ...

Ballon catheter systems for delivery of dry drug delivery vesicles to a vessel in the body

Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles, disposed at a suitable location within the balloon or catheter. The reservoir may be installed within the angioplasty balloon, within a lumen in communication with the angioplasty balloon, either as a loose or packed powder or as a film coating. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.

Enteral feeding catheter assembly incorporating an indicator

A catheter assembly (20) incorporating a pre-biased indicator (22), the assembly includes a catheter (26) having a proximal end (28), a distal end (30), and catheter walls (32) defining a catheter lumen (34). The assembly further includes a base (36) located at the proximal end (28) of the catheter, the base defining an opening to the catheter lumen, the base having a first end (42) and a second end (44). An inflatable balloon (24) having a predetermined fill volume is located at a distal end (30) of the catheter. An inflation valve (46) is located on the base (36); the inflation valve is in fluid communication with the balloon through an inflation lumen (48) defined by the catheter walls (32). The pre-biased indicator located on the base in fluid communication with the balloon is configured to provide a discrete visual signal that the pressure of a fluid in the balloon is different from a predetermined level of pressure or the volume of the balloon is different from the predetermined fill ...

Instrument for fluid injection and dilatation probe for implantation in body cavities

Stretch valve balloon catheter and methods for producing and using same

A safety balloon catheter includes a stretch valve and a balloon catheter having a proximal catheter end, a balloon defining an interior to be inflated with an inflation fluid, an inflation lumen extending through the shaft to the interior and shaped to convey inflation fluid thereto and from, a second lumen parallel to the inflation lumen, and a balloon drainage port fluidically connecting the balloon 10 interior to the second lumen.

A balloon catheter or a device to be used together with a balloon catheter

BALLOON CATHETER SYSTEMS FOR DELIVERY OF DRY DRUG DELIVERY VESICLES TO A VESSEL IN THE BODY

CYSTOMETRY SYSTEM

PF-1415 CYSTOMETRY SYSTEM A cystometry system to measure the pressure-volume relationship in the bladder of a patient from a source of fluid comprising, a catheter having an elongated shaft defining an infusion lumen communicating with an infusion opening adjacent a distal end of the shaft, and a pressure lumen communicating with a pressure opening adjacent the distal end of the shaft. The system has a device for supplying a selected volume of fluid from the source to the bladder through the infusion lumen of the catheter, and a device for measuring the bladder pressure through the catheter pressure lumen.

INFLATING AND DEFLATING DEVICE FOR VASCULAR DILATING CATHETER ASSEMBLY

A-36726-1/HCH Inflating and deflating device adapted to be used by a human hand. It comprises a housing and a syringe carried by the housing. The syringe comprises a syringe body having an outlet through which liquid can pass and a piston slidably mounted in the syringe body and forming a sealing engagement with the body. A piston rod is secured to the piston and extends out of the body. A tubular member is provided. A connector means connects the tubular member to the outlet of the syringe body. A handle is carried by the housing and is secured to the syringe for causing relative movement between the piston and the syringe body. The handle means includes first and second portions movable with respect to each other. The first portion is secured to one of said piston rod or said syringe body and the other said portions are secured to one of the other of said piston rod and said syringe body. The first portion is of a size so as to be adapted to being engaged by all of the fingers of the ...

PATIENT MONITORING APPARATUS

PATIENT MONITORING APPARATUS A method of monitoring the depth of anaesthesia of a patient, comprising stimulating contractions in the oesophagus of the patient, for example using an inflatable oesophageal balloon, obtaining signals inductive of the oesophageal contractions using a sensor, and deriving from the signals an output indicative of the rate of occurrence of signals having a magnitude greater than a preset threshold value, and apparatus for carrying out the method. An alternative aspect comprises assigning a score value to each of a plurality of different bodily functions of a patient, for example heart rate, blood pressure, degree of sweating, and formation of tears, the said score values being indicative of a depth of anaesthesia or sedation, summing the score values, and producing an output from the summed score values indicative of the amount of anaesthetic to be fed to the patient.

SOFT BALLOON DEVICE AND SYSTEM

A device, system, and method for performing a variety of treatment procedures safely with a single treatment device. For example, a system is provided that includes a treatment device with a highly conformable balloon that is inflated at a constant pressure and that remains "soft" during use, which enhances balloon-tissue contact, treatment efficacy, and patient safety. In one embodiment, a system for ablating tissue comprises: a treatment device including a highly conformable balloon; a control unit including a fluid supply reservoir in fluid communication with the highly conformable balloon, the control unit being configured to deliver fluid from the fluid supply reservoir to the highly conformable balloon such that the highly conformable balloon is maintained at a balloon pressure of between 0.2 psig and 3.0 psig.

UTERINE MANIPULATOR

A uterine manipulator device includes: an elongated cannulated tube comprising a proximal end and a distal end; a cervical cup having a top proximal portion of a first diameter and a base distal portion of a second smaller diameter, wherein: the base distal portion includes a hole formed therein having a perimeter including a distal end and a proximal end, and including a longitudinal axis positioned therethrough; one of the proximal end of the perimeter and the distal end of the perimeter is angled away from the longitudinal axis and the other of the proximal end of the perimeter and the distal end of the perimeter is in line with the longitudinal axis; and the elongated cannulated tube is positioned through the hole in the cervical cup.

OSTOMY DEVICE, APPARATUS, AND SYSTEM

Devices for insertion into a stoma formed in a patient's body are provided, comprising a tube having distal and proximal ends and defining a path for movement of waste. To retain the device in the stoma and seal the stoma, the tube includes a retention mechanism located on the distal end and/or a sealing mechanism extending along a length of the tube between the proximal and distal ends. Collection apparatus for collecting waste from a patient's body also are provided, comprising a waste pouch and a connector for connecting the collection apparatus to a device inserted into a stoma. Additionally, waste collection systems for collecting waste from a patient's body are provided, comprising a tube for insertion into a stoma and a waste pouch. Each system may comprise a separate tube and waste pouch or the tube and waste pouch may be formed as an integral, inseparable component.

INFLATABLE MEDICAL DEVICES

An inflatable structure for use in biological lumens and methods of making and using the same are disclosed. The structure can have an inflatable balloon encircled by a shell. The shell can have proximal and distal tapered necks, longitudinally-oriented flutes, and apertures at the proximal and distal ends of the shell. The apertures can be recessed in the flutes in the necks. The shell can also have fiber reinforced walls.

PERFUSION BALLOON WITH EXTERNAL VALVE

An apparatus (10) for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus includes an inflatable perfusion balloon (12) including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, the balloon including a plurality of cells (12a) in a single cross section and a covering for at least partially covering (18) the cells. A valve (20) associated with the balloon controls the fluid flow within the passage, the valve being arranged external to the passage. The valve may form a tubular extension (18a) of the covering, or may be separate from the covering, and may comprise flaps (22, 30a). A spiral covering (28) may also form the valve.

PERFUSION BALLOON WITH INTERNAL VALVE

An apparatus 10 for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus comprises a shaft 16, an inflatable perfusion balloon 12 supported by the shaft and including an internal passage P for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, and a valve 18 for controlling the fluid flow within the passage. The valve may be connected to the shaft, or may comprise an elongated tube partially connected to the balloon. The balloon may comprise a plurality of cells in a single cross-section, each cell including a neck, and the valve may be positioned in a space between the shaft and the necks for controlling the fluid flow within the passage. A connector may also be provided to control the position of the valve.

BALLOON CATHETER SYSTEMS FOR DELIVERY OF DRY DRUG DELIVERY VESICLES TO A VESSEL IN THE BODY

CALIBRATION OF IN VIVO BLOOD PRESSURE SENSORS

A method for performing an in-vivo calibration of a blood pressure sensor 40 that is associated with an in-vivo balloon system. The method involves monitoring a patient's blood pressure by observing the system gas pressure while at the same time monitoring the patient's blood pressure through the sensor. The blood pressure measurements obtained by monitoring the system gas pressure are used as reference, or "true, " blood pressure measurements, and an "offset" is determined between the reference blood pressure measurements and the blood pressure measurements obtained through the sensor. The offset can be stored in a memory 42, which may also store sensor sensitivity data. The offset and/or sensitivity data may be used to adjust future measurements obtained from the sensor, thereby generating calibrated sensor measurements.

CORRUGATED BALLOON CATHETER AND METHODS OF USE THEREOF

... lA balloon catheter including an outer conduit, an inner conduit disposed within the lumen of the outer conduit. The distal tip of the inner conduit extends beyond the distal tip of the outer conduit. The inner conduit is capable of being longitudinally moved within the outer conduit. An inflatable balloon has a proximal margin attached to the outer surface of the outer conduit's distal tip, and a distal margin attached to the outer surface of the portion of inner conduit extending beyond the distal tip of the outer conduit. The balloon has at least one corrugated portion. The distal end portion of the balloon is capable of intussuscepting upon proximal movement of the inner conduit within the outer conduit. The catheter has a fluid port for introducing an inflation fluid into the space formed between the outer conduit and the inner conduit and into the lumen of the balloon.

APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS

An apparatus is provided that operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including a proximal end, a distal end, a lumen extending therebetween, and a balloon on the distal end having an interior communicating with the lumen. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The -apparatus also includes an actuator for axially compressing the balloon, and a helical member extends between ends of the balloon interior that expands the balloon from a contracted condition to an expanded helical shape when the actuator is activated.

APPARATUS FOR PREVENTING OVER INFLATION OF THE RETENTION BALLOON IN MEDICAL CATHETERS AND AIRWAY DEVICES

The body has a fluid inlet port for receiving pressurized fluid and a fluid outlet port connected to the retention balloon. A first passage connects the fluid inlet port and the fluid outlet port, A second passage in the body is connected to the balloon fluid return path and is at the pressure of the retention balloon. A. valve prevents fluid flow through the first passage when actuated. The valve includes a pressure-responsive member movable to a position to obstruct fluid flow in response to fluid pressure in the second passage exceeding the predetermined level. Flexible means such as a membrane defines a normally open portion of the first fluid passage, which is closed by the moveable means bearing on the membrane when pressure exceeding the predetermined level actuates the valve.

Balloon catheter exhibiting rapid inflation and deflation

A catheter capable of rapid inflation and deflation and operation by one individual.

Balloon catheter with improved pressure source

A balloon catheter is disclosed which includes a contrast displacement rod at least partially and slidably disposed in an elongate tubular member with a balloon connected to the distal end of the tubular member. The rod may include a stop mechanism to inhibit removal of the rod from the tubular member. A seal connected to the proximal end of the tubular member creates a liquid tight seal between the inside of the tubular member and the displacement rod. Accordingly, longitudinal actuation of the displacement rod causes the balloon to expand and/or contract. The balloon catheter may be a fixed wire, an over-the-wire or a single-operator exchange type balloon catheter. In addition, a pressure gauge may be connected to the proximal end of the tubular member. A one-way valve is also disclosed which allows the balloon catheter to be prepped via the guide wire lumen. Accordingly, the present invention negates the need for both an inflation device and an inflation lumen which results in a significant ...

Pressure limiting device

An apparatus for limiting the pressure of inflation fluid injected into one or more balloon of a catheter device comprising a reservoir chamber having an inlet port coupled in fluid communication with an inflation/deflation device and a plurality of outlet ports coupled in fluid communication with a plurality of cylindrical housings. Each cylindrical housing includes a pressure chamber and a valve chamber. The valve chamber receives a piston moveable between a fully open position and a closed position and spring biased toward the fully open position. Each housing includes an outlet port coupled in fluid communication with a separate balloon of a catheter device. Each piston includes an internal flow path which enables the flow of pressurized inflation fluid from the reservoir chamber to the balloon catheter when the pressure of the inflation fluid within the balloon is below the desired cut-off pressure. As the pressure of the inflation fluid within each balloon increases, the associated ...

Method of emboli protection using a low profile catheter

Disclosed herein is a low profile catheter valve comprising a movable sealer portion positioned within the inflation lumen of a catheter. The sealer portion forms a fluid tight seal with the inflation lumen by firmly contacting the entire circumference of a section of the inflation lumen. The sealer portion may be positioned proximally of a side-access inflation port on the catheter, to establish an unrestricted fluid pathway between the inflation port and an inflatable balloon on the distal end of the catheter. As desired, the clinician may move the sealer portion to a position distal of the inflation port, thereby preventing any fluid from being introduced into or withdrawn from the balloon via the inflation port.

Valve assemblies

A valve assembly comprises a resilient housing of plastic material and a valve element in the form of a unitary plastic body located within the housing. The body is closed at one end by a dish-shape portion having a circumferential lip which forms a seal with the housing. The body has a tongue formed in its wall, one end of the tongue being provided with an inwardly directed tooth. By inserting a tube or rod within the valve element to engage the tooth, the tongue can be displaced outwardly and the overlying part of the housing can thereby be distorted away from the lip to permit fluid flow through the housing. The valve assembly may be used to seal one end of the inflation line of a cuffed medico-surgical tube.

Balloon catheters with increased column strength

An intravascular balloon catheter that may include, for example, a first elongate member having a proximal end, an opening at the distal end and a lumen therebetween, a balloon defining a cavity, the balloon having a proximal waist sealingly attached to the first elongate member proximal the distal end, a distal waist, and a tubular portion therebetween, a second elongate member having a proximal end, a distal end and a lumen therebetween, the second elongate member disposed in the first elongate member and sealingly attached to the balloon distal waist, and a stopper attached to the second elongate member and disposed in the balloon cavity distal the distal end of the first elongate member, the stopper having an outer profile that prevents movement of the first elongate member thereover the first elongate member having an inner diameter at the distal end large enough to permit the passage of fluid therethrough over the second elongate member.

Operating a vessel occlusion catheter

Some systems and methods for operating a vessel occlusion catheter may include a control and inflation device to control the filling of the balloon in such a manner that the vessel wall will not be overstressed while the safe occlusion of the blood vessel is achieved.

METHOD AND APPARATUS FOR DISTRACTING A JOINT

A joint-spacing balloon catheter comprising: a shaft having a distal end and a proximal end; first and second balloons mounted to the distal end of the shaft, the first balloon being disposed distal to, and spaced from, the second balloon, with the portion of the shaft between the first and second balloons being flexible; and a handle attached to the proximal end of the shaft.

PACING SYSTEM CONTROLLER INTEGRATED INTO INDEFLATOR

Systems and methods for temporarily pacing a patient's heart are provided. One system includes a vascular treatment system having a vascular access system and a therapy system. The therapy system includes an indeflator and an elongate medical device and the elongate medical device has an inflatable member and an electrode. The indeflator is adapted to provide pressurized fluid to the inflatable member and electrical signals to the electrode, with its operation manually or automatically controlled. Devices for electrically and fluidly coupling the indeflator and the elongate medical device are also provided.

Balloon inflation device

One embodiment provides a method implemented by a powered inflation device to prepare a balloon catheter for use during a medical procedure. In this embodiment, the method includes drawing an amount of medical fluid from a fluid reservoir into the inflation device during a first motorized operation of the inflation device, removing an amount of air from the balloon catheter during a second motorized operation of the inflation device, and injecting the amount of medical fluid from the inflation device into the balloon catheter during a third motorized operation of the inflation device to inflate a balloon located at a distal end of the balloon catheter. The powered inflation device may be a stand-alone device in one embodiment. In one embodiment, the powered inflation device is coupled to an angiographic injector system. When it is coupled to an angiographic injector system, the balloon inflation device and the injector system may be controlled by a common control panel, or console, in one ...

BALLOON-ASSISTED NEUROVASCULAR THROMBECTOMY DUAL ASPIRATION AND DISTAL ACCESS CATHETER SYSTEM

A catheter system that allows balloon occlusion for flow-arrest assisted aspiration in the intracranial circulation with direct aspiration. The system has an inner coaxial floppy intra-cranial aspiration catheter that allows for direct thrombectomy of proximal and distal vessel blockages in a single device, through direct or remote aspiration with enhanced flow arrest of the intracranial circulation via balloon inflation. Rapid deflation of the balloon is achieved with withdrawal of the inner aspiration on thrombus retrieval, for seamless reperfusion of the vessel, and the system can provide continuous aspiration via an outer aspiration catheter. Automatic deflation of the balloon occurs with retrieval of the inner co-axial floppy intra-cranial aspiration catheter under continuous aspiration to guard against prolonged balloon time inflation and risk of vessel injury during the revascularization procedure.

BALLOON CATHETER

PROBLEM TO BE SOLVED: To provide a balloon catheter capable of placing a balloon in the inflated state inside the body cavity. SOLUTION: The balloon catheter A is composed of a balloon member 1 to which a balloon part 12 and a valve element 15 are integrally attached, a tubular catheter body 2 to detachably attach the balloon member 1 to the distal end with the valve element 15 in the opened state, a connection part 2a integrally attached to the distal end of the catheter body 2, and an outer barrel 3 fitted to the catheter body 2. The connection part 2a is composed of a locking piece 25 to be detachably locked to a locking hole 13 formed at the proximal end of the balloon member 1 and a resilient member to energize the catheter body 2 in the direction of separating from the balloon member 1 with the locking piece 25 locked with the locking hole 13 of the balloon member 1. COPYRIGHT: (C)2007,JPO&INPIT ...

РЕКТАЛЬНОЕ ДРЕНАЖНОЕ ПРИСПОСОБЛЕНИЕ

... 1. Ректальное дренажное приспособление, включающее: ! трубчатый элемент, определяющий прохождение дренажа, для выведения экскрементов из прямой кишки; ! надувной баллон на первом дистальном конце трубчатого элемента для вставления в прямую кишку; ! вспомогательный просвет, сообщающийся с надувным баллоном; и ! индикатор давления, присоединенный к вспомогательному просвету для индикации уровня давления в баллоне, при этом указанный индикатор давления включает первый механический элемент, сконфигурированный для переключения между первым и вторым физическими состояниями в зависимости от воспринимаемого давления. ! 2. Ректальное дренажное приспособление по п.1, в котором механический элемент выполнен с возможностью деформирования, а первое и второе состояния представляют собой первую и вторую формы механического элемента. ! 3. Ректальное дренажное приспособление по п.1, в котором механический элемент имеет трехмерный профиль, способный к деформации. ! 4. Ректальное дренажное приспособление ...

ПЕРФУЗИОННЫЙ БАЛЛОН С ВНУТРЕННИМ КЛАПАНОМ

SELBSTABDICHTENDES RUECKSCHLAG- BZW. ABSPERRVENTIL

SYRINGE CHECK VALVE

Pressure control systems

A pneumatically controlled pressure relief valve and various systems incorporating a pneumatically controlled pressure relief valve. The valve has a flexible valve closure member which is expandable to close a through passage of the valve and includes a pressure chamber disposed externally of the valve passage and isolated from the through passage by the flexible valve closure member so that the valve may open and close in response to the differential between the pressure in the pressure chamber and the pressure in the through passage of the valve. An input passage opens into the pressure chamber for admitting air and a manually operable valve is provided for opening and closing the input passage to regulate the admission of air. The systems incorporating the valve include an inflatable cuff system for a tracheal or endotracheal tube, a positive end expiratory pressure system and a suction system incorporating a suction catheter.

Balloon catheter device for use in a aorta of a rabit or human being

CATHETER VALVE WITH LOW PROFILE

INFLATION DEVICE WITH STORE

DRUG DELIVERY CATHETER WITH A HIGH-FLEXIBLE BALLOON WITH INFUSION HOLES

Perfusion balloon with external valve

An apparatus (10) for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus includes an inflatable perfusion balloon (12) including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, the balloon including a plurality of cells (12a) in a single cross section and a covering for at least partially covering (18) the cells. A valve (20) associated with the balloon controls the fluid flow within the passage, the valve being arranged external to the passage. The valve may form a tubular extension (18a) of the covering, or may be separate from the covering, and may comprise flaps (22, 30a). A spiral covering (28) may also form the valve.

Enteral feeding catheter assembly incorporating an indicator

A catheter assembly (20) incorporating a pre-biased indicator (22), the assembly includes a catheter (26) having a proximal end (28), a distal end (30), and catheter walls (32) defining a catheter lumen (34). The assembly further includes a base (36) located at the proximal end (28) of the catheter, the base defining an opening to the catheter lumen, the base having a first end (42) and a second end (44). An inflatable balloon (24) having a predetermined fill volume is located at a distal end (30) of the catheter. An inflation valve (46) is located on the base (36); the inflation valve is in fluid communication with the balloon through an inflation lumen (48) defined by the catheter walls (32). The pre-biased indicator located on the base in fluid communication with the balloon is configured to provide a discrete visual signal that the pressure of a fluid in the balloon is different from a predetermined level of pressure or the volume of the balloon is different from the predetermined fill ...

Ostomy device, apparatus, and system

Devices for insertion into a stoma formed in a patient's body are provided, comprising a tube having distal and proximal ends and defining a path for movement of waste. To retain the device in the stoma and seal the stoma, the tube includes a retention mechanism located on the distal end and/or a sealing mechanism extending along a length of the tube between the proximal and distal ends. Collection apparatus for collecting waste from a patient's body also are provided, comprising a waste pouch and a connector for connecting the collection apparatus to a device inserted into a stoma. Additionally, waste collection systems for collecting waste from a patient's body are provided, comprising a tube for insertion into a stoma and a waste pouch. Each system may comprise a separate tube and waste pouch or the tube and waste pouch may be formed as an integral, inseparable component.

Diagnostic drainage catheter assembly and methods

A vesical pressure measurement system is provided. One or more elements of the system are operably combinable with a previously deployed urinary drainage catheter. The system includes a urodynamic data system and a urinary drainage catheter balloon adaptor. The data system is characterized by a pressure sensor for vesical pressure measurement, and a processor/controller for receiving, processing and/or displaying select urodynamic patient parameters comprising sensed/monitored pressure data. The adaptor operably unites the pressure sensor of the data system to a balloon inflation valve of the catheter. The adaptor includes an adaptor valve for connection to the balloon inflation valve, and a housing, the housing including a balloon inflation valve portion and an adaptor valve portion, the portions urgingly uniteable in furtherance of establishing and maintaining a secure interface between the balloon inflation valve and the adaptor valve.

Apparatus and methods for treating obstructions within body lumens

An apparatus is provided that operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including a proximal end, a distal end, a lumen extending therebetween, and a balloon on the distal end having an interior communicating with the lumen. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The -apparatus also includes an actuator for axially compressing the balloon, and a helical member extends between ends of the balloon interior that expands the balloon from a contracted condition to an expanded helical shape when the actuator is activated.

INFLATION VALVE

SELF-SEALING CHECK VALVE

VASCULAR DILATING DEVICE

... 70085-3 A vascular dilating device for performing a coronary angioplasty procedure that includes a tubular barrel defining a reservoir for containing a supply of actuating fluid and having a plunger and connected piston reciprocially disposed within the reservoir. The outlet of the reservoir is connected to a valve assembly having an outlet to which a balloon catheter is connected. The valve assembly includes a control valve and a unidirectional valve which are co-operatively associated for directing fluid from the reservoir to the balloon catheter in one direction only when the control valve is disposed in a balloon inflating position and the handle is actuated to advance the plunger. A by-pass is also provided in the valve assembly to reserve the fluid flow from the balloon catheter to the reservoir when the control valve is disposed in a second or balloon deflating position. The handle construction includes a actuating lever member disposed in bearing or driving relationship to the plunger ...

VALVE DEVICE

A fluid such as air is tightly enclosed in a chamber which serves to plug an organic passage such as a person's nasal cavity. The fluid is supplied into the chamber through a tube so as elastically to expand the chamber and thereafter is discharged through a valve device comprising an opening formed in the tube and a valve member which normally closes the opening but can be rolled up on itself so that the fluid in the chamber can flow out through the opening.

THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE

Embodiments of the invention provide swallowable devices, preparations and methods for delivering therapeutic agents (TA) within the GI tract. Many embodiments provide a swallowable device such as a capsule for delivering TAs into the intestinal wall (IW) or other GI location. Embodiments also provide various TA preparations such as IgG that are configured to be contained within the capsule, advanced from the capsule into the IW and degrade to release the TA into the bloodstream where they exhibit a selected plasma concentration profile which may have selected pharmacokinetic parameters. The preparation can be operably coupled to a delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the IW. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.

WASTE MANAGEMENT APPLIANCE

A waste management appliance comprising: a tubular body; a balloon coupled to the tubular body in the vicinity of the proximal end thereof; an inflation lumen opening at a proximal end to the interior of said balloon and extending distally from the balloon towards the distal end of the tubular body, and a valve assembly (1) fluidly coupled to the inflation lumen, the valve assembly comprising (1) a valve body having first and second valve chambers (3, 5) in fluid communication with said inflation lumen, a coupling for connecting the lumen to a source of fluid being provided in said first chamber (3), and a pressure relief valve (11) being provided in said second chamber (5); the insertion of fluid into said lumen inflates said balloon until the balloon contains a predetermined quantity of fluid, whereupon continued insertion of fluid causes said pressure relief valve (11) to operate.

MOTORIZED CATHETER SYSTEM WITH IMPROVED INFLATION CONTROL

A method and system for automated controlling of inflation of an inflatable retention member, e.g. a balloon, in a catheter is disclosed. The catheter is preferably a rectal or anal catheter, and the inflation is controlled by a controller. A plurality of predetermined inflation levels are provided, and for each of level, a pumping time threshold and a pressure level threshold are defined. The pressure in the balloon is continuously measured during the inflation. An inflation level is selected form said plurality of inflation levels, and an electric pump is used to inflate the inflatable retention member. Operation of the electric pump is continued until one of the pumping time threshold and pressure level threshold of the selected inflation level has been reached.

CATHETER WITH VALVE

INFLATING AND DEFLATING DEVICE FOR VASCULAR DILATING CATHETER ASSEMBLY

DEFLATION MECHANISM FOR A MEDICAL DEVICE

A method and system for delivering coolant to a medical device having an expandable element, a guidewire lumen movable within the medical device, and an actuator element coupled to the guidewire lumen for manipulation of longitudinal movement thereof is provided, including transferring a fluid from a console to the medical device to inflate the expandable element; manipulating the actuator element, and initiating a predetermined fluid control sequence of the console in response to the manipulation of the actuator element.

RESECTOR BALLOON SYSTEM

A resector balloon system is disclosed generally comprising a catheter with at least one balloon having an outer wall with a resecting, non-slip surface for resecting unwanted biological material, such as tissues or tumors, and a pump that supplies fluid thereto in pulsed fashion to repeatedly deflate and inflate said balloon. In certain embodiments, the pump includes a processor that controls the pulsed supply of fluid based on an established frequency or change in volume. In some embodiments, the system includes a keyed connector with which the pump identifies the balloon type, and in some cases, the system calculates intra-lumen diameters and densities. In some embodiments, the balloon portion of the catheter includes multiple balloon segments, which in some cases, are inflatable separately from one another.

TAPERED MULTI-CHAMBER BALLOON

A catheter (10) for carotid artery dilatation that includes a multi-chamber balloon assembly (13) mounted at the distal end of the elongated tube that has at least two tandem chambers. Each chamber (21, 22, 23) communicates with a separate lumen and each separate lumen terminates at the proximal end at a lumen valve head. The chambers have an inflated configuration with a diameter that progressively tapers in a direction from proximal to distal, said taper extends substantially continuously from the proximal end of the balloon assembly to the distal end thereof.

INTRAGASTRIC DEVICE

Devices and methods for treating obesity are provided. More particularly, intragastric devices and devices for inflating and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided.

INTEGRATED BALLOON CATHETER INFLATION SYSTEM

An inflation system having two pressure vessels integrated into a balloon catheter. A pressurized chamber and a vacuum chamber are integrally attached to proximal end of the balloon catheter and activated by a common valve or switch. Pressure or vacuum is selectively transmitted to the balloon depending on the valve/switch position. The working fluid may be air, or a combination of air and saline with an intermediate piston/cylinder assembly. The balloon catheter may be a part of a heart valve delivery system with a balloon-expandable heart valve crimped onto the balloon.

STRETCH VALVE BALLOON CATHETER AND METHODS FOR PRODUCING AND USING SAME

A safety balloon catheter includes a stretch valve and a balloon catheter having a proximal catheter end, a balloon defining an interior to be inflated with an inflation fluid, an inflation lumen extending through the shaft to the interior and shaped to convey inflation fluid thereto and from, a second lumen parallel to the inflation lumen, and a balloon drainage port fluidically connecting the balloon 10 interior to the second lumen.

OPEN-PORE BALLOON CATHETER

The invention relates to a catheter (20), in particular a balloon catheter, having a fluid-carrying element (2), such as a drainage tube, with an inner lumen (2g) for carrying away body fluid, and having an expansion element, such as a balloon (1) of variable cross section, for fixing the catheter in a body cavity. The fluid-carrying element (2) has a wall portion (2c) of an open-pore material (3), which is in fluidic communication with the inner lumen (2g) and through which the body fluid can be aspirated into the inner lumen (2g) by applying a negative pressure to a proximal end of the fluid-carrying element (2). The invention furthermore relates to a catheter system having a catheter of the invention and to a vacuum-generating system connected to the catheter.

PATIENT MONITORING APPARATUS

DRAINAGE APPLIANCE FOR BODY WASTE

A drainage appliance includes a distal portion with a distensible retention cuff for retaining the distal portion in the rectum, intestinal or urinary tract. Cuff distension is controlled by a combination of: (a) a resiliently deformable device for urging distension of the cuff; (b) a fluid-containing chamber of variable size; and (c) a fluid-transfer damper for restricting fluid flow with respect to the chamber when the chamber changes size.

FLUID FLOW CHECK VALVE

A valve for controlling the flow of fluid through a flow path, which valve comprises a housing (4) defining a flow path (5) and having two indented portions (3) about the flow path, a poppet (2) mounted within each indented portion such that the internal end of each indented portion defines a seat (8) which provides a fluid tight seal when the associated poppet head is held against the seat, spring means (7) associated with each poppet for holding each poppet against each seat, a rigid moveable member (9) associated with each poppet and adapted to alter the orientation of the associated poppet relative to its seat and thereby seal or unseal the flow path around the poppet, and actuating means (10) for moving each movable member; and inflator apparatus incorporating at least one valve.

DEVICE OF INFLATION Of a SURGICAL IMPLANT

Surgical probe

CATHETER EQUIPS With a VALVE

IMPROVED BALLOON CATHETER EXHIBITING RAPID INFLATION AND DEFLATION

A catheter capable of rapid inflation and deflation and operation by one individual.

AN ARRANGEMENT FOR IMPLEMENTING KISSING BALLOONS FOR SIMULATING A BIFURCATED VESSEL, A KIT, A METHOD OF MANUFACTURING THE ARRANGEMENT AND A CATHETER PROVIDED WITH A BUFFER VOLUME

The invention relates to an arrangement (10) for implementing kissing balloons simulating a bifurcated vessel, comprising a first catheter (4) having a first inflatable balloon (6) at or near its distal portion, a second catheter (7) having a second inflatable balloon (7a) at or near its distal portion, wherein the first catheter comprises a holding element (4) provided on the said first balloon (6), the said holding element (4) being adapted for: allowing the distal portion of the second catheter (7) to pass there through; affixing the second catheter (7) in a proximal vicinity to the first catheter (4) so that, in use, respective facing surfaces of the inflated first balloon (6) and the inflated second balloon (7a) touch each other.

METHOD AND APPARATUS FOR DISTRACTING A JOINT

A joint-spacing balloon catheter comprising: a shaft having a distal end and a proximal end; first and second balloons mounted to the distal end of the shaft, the first balloon being disposed distal to, and spaced from, the second balloon, with the portion of the shaft between the first and second balloons being flexible; and a handle attached to the proximal end of the shaft.

Method and apparatus for distracting a joint

A joint-spacing balloon catheter comprising: a shaft having a distal end and a proximal end; first and second balloons mounted to the distal end of the shaft, the first balloon being disposed distal to, and spaced from, the second balloon, with the portion of the shaft between the first and second balloons being flexible; and a handle attached to the proximal end of the shaft.

Zero-pressure balloon catheter and method for using the catheter

A safety catheter includes a shaft. The shaft has a proximal shaft portion having a proximal end, a distal tip portion defining a junction with the proximal shaft portion, a fluid drain lumen, and a balloon inflation lumen. The fluid drain lumen defines a distal fluid drain opening at the distal tip portion distal of the junction and a proximal fluid drain opening adjacent the proximal end and fluidically connected to the distal fluid drain opening. A hollow zero-pressure balloon is disposed at the junction and has an interior fluidly connected to the balloon inflation lumen, a distal leg fixedly secured to the distal tip portion, and a proximal leg temporarily secured to the proximal shaft portion.

Gravity thermal dilator

SYSTEM AND METHOD FOR LOW PROFILE OCCLUSION BALLOON CATHETER

An occlusion catheter system for full or partial occlusion of a vessel having a vessel diameter includes a proximal catheter shaft having a proximal lumen and a hypotube positioned partially within the proximal lumen and spaced from the proximal catheter shaft. The catheter system also includes a distal catheter shaft attached to a distal end of the hypotube and an occlusion balloon connected at a proximal end to the proximal catheter shaft and at a distal end to the distal catheter shaft. The occlusion balloon is configured to define flow channels with inner surfaces of the vessel at folds in the occlusion balloon when the occlusion balloon is partially inflated and in engagement with the inner surfaces.

DEVICE FOR INDEPENDENTLY INFLATING, DEFLATING, SUPPLYING CONTRAST MEDIA TO AND MONITORING UP TO TWO BALLOON CATHETERS FOR ANGIOPLASTY

An adaptable inflation device for up to two balloon catheters for angioplasty includes a plurality of three port valves controlling flow to two fluid channels each coupled at an outlet to a balloon catheter for angioplasty. A single in line pressure gauge, which may be removable, monitors pressure of each channel. Each balloon catheter may be inflated and deflated, sequentially inflated, simultaneously inflated, sequentially deflated, simultaneously deflated, inflated to the same pressures, inflated to different pressures, partially deflated, and fully deflated.

Catheter support for stent delivery

An angioplasty and stent delivery system to facilitate introduction and placement of a stent, including a catheter having an expandable distal portion constructed and arranged for expanding the outer diameter of the catheter from a contracted state to an expanded state: a stent positioned around the distal portion of the catheter having a contracted condition and being expandable to an expanded condition, and being sized in the contracted condition to closely surround the catheter in the contracted state, the expandable distal portion of the catheter including a balloon within which or over which there is included on a catheter shaft at least one axially movable or enlargeable body of a diameter larger than the catheter shaft to which the stent and balloon are fitted, as by crimping, for holding the stent in place until it is released therefrom by expansion of the balloon.

Method and apparatus for inflating and deflating balloon catheters

A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted.

УСТРОЙСТВО ДЛЯ ПРОВЕДЕНИЯ МЕДИЦИНСКОЙ ПРОЦЕДУРЫ В СОСУДЕ ДЛЯ ПЕРЕДАЧИ ПОТОКА ТЕКУЧЕЙ СРЕДЫ (ВАРИАНТЫ)

Группа изобретений относится к медицинской технике, а именно к устройствам для проведения медицинской процедуры в сосуде для передачи потока текучей среды, и в частности к перфузионным баллонам, которые могут использоваться для регулирования потока текучей среды в процессе проведения процедуры, особенно при использовании в связи с процедурой, при которой клапан не способен функционировать в результате проведения этой процедуры или по иной причине. Устройство для проведения медицинской процедуры в сосуде для передачи потока текучей среды содержит стержень; надувной перфузионный баллон, поддерживаемый стержнем и содержащий внутренний проход для прохождения потока текучей среды в сосуде, когда перфузионный баллон находится в раздутом состоянии; а также клапан, соединенный со стержнем, для управления потоком текучей среды во внутреннем проходе. В соответствии со вторым вариантом осуществления устройство для проведения медицинской процедуры в сосуде для передачи потока текучей среды содержит ...

УСТРОЙСТВО ДЛЯ ПРОВЕДЕНИЯ МЕДИЦИНСКОЙ ПРОЦЕДУРЫ В СОСУДЕ ДЛЯ ПЕРЕДАЧИ ПОТОКА ТЕКУЧЕЙ СРЕДЫ (ВАРИАНТЫ)

Группа изобретений относится к области медицинской техники, а именно к устройствам для проведения медицинской процедуры в сосуде для передачи потока текучей среды, и в частности к перфузионным баллонам, которые можно использовать для регулирования потока текучей среды в процессе проведения процедуры, особенно при использовании в связи с процедурой, при которой клапан не способен функционировать в результате проведения этой процедуры или по иной причине. Устройство для проведения медицинской процедуры в сосуде для передачи потока текучей среды содержит надувной перфузионный баллон, а также клапан. Надувной перфузионный баллон содержит внутренний проход, имеющий входы для прохождения потока текучей среды в сосуде, когда перфузионный баллон находится в раздутом состоянии. Клапан связан с баллоном для управления потоком текучей среды в проходе. Клапан предназначен для селективного перекрывания входов в проход с целью управления потоком текучей среды, проходящим в этом проходе. В соответствии ...

СПОСОБЫ И АППАРАТ ДЛЯ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ УХА, ГОРЛА, НОСА

Изобретение относится к медицине и может быть использовано для расширения устья околоносовой пазухи человека или животного. Устройство может содержать: расширитель, проволочный направитель, рукоятку и вытянутый ствол, который проксимальным концом соединен с рукояткой и проходит к дистальному концу. Проволочный направитель проходит через, по меньшей мере, часть просвета ствола. Расширитель имеет нерасширенную конфигурацию и расширенную конфигурацию. Скользящий элемент соединен с проволочным направителем и (или) расширителем через продольное отверстие ствола для продвижения проволочного направителя и (или) расширителя относительно ствола. 3 н. и 10 з.п. ф-лы, 20 ил.

БЛОК КАТЕТЕРА ЭНТЕРАЛЬНОГО ПИТАНИЯ, ВКЛЮЧАЮЩИЙ ИНДИКАТОР

... 1. Блок катетера энтерального питания, содержащий:катетер, имеющий проксимальный конец, дистальный конец и стенки катетера, образующие полость катетера;основание, расположенное у проксимального конца катетера, причем основание образует отверстие в полость катетера, при этом основание имеет первый конец и второй конец;накачиваемый баллон, имеющий заданный объем заполнения, причем баллон расположен на дистальном конце катетера;клапан накачивания, расположенный на основании, причем клапан накачивания находится в жидкостном сообщении с баллоном посредством полости накачивания, образованной стенками катетера; ииндикатор предварительного смещения, расположенный на основании, находящийся в жидкостном сообщении с баллоном, причем индикатор предварительного смещения выполнен так, чтобы обеспечивать дискретный визуальный сигнал, о том, что давление текучей среды в баллоне отличается от заданного уровня давления или объем баллона отличается от заданного объема заполнения.2. Блок катетера энтерального ...

ОТКРЫТОПОРИСТЫЙ БАЛЛОННЫЙ КАТЕТЕР

Nasal membrane pressure instrument - has controller between pressure source and inflatable balloon

The instrument presses a nasal mucous membrane against enclosing tissue. It comprises an inflatable balloon (1) connected to a pressure source (3), there being a controller (2) in between for the degree to which the balloon is filled. The supply can comprise a plunger pump with cylinder, typically a plastics syringe, and connected by a hose to the controller. ADVANTAGE - Ensures even pressurisation of membrane.

VORRICHTUNG ZUM EINSPRITZEN EINES FLUIDS UND DILATIONSSONDE ZUM IMPLANTIEREN IN KÖRPERHÖHLEN

Quick release screw and nut actuating mechanism for use with the plunger of a syringe

The present invention provides an improved pressurization device for use with angioplasty balloon catheters, or the like. The device has a novel quick release mechanism which enables rapid advancement of a threaded screw plunger to attain initial pressurization, and then the subsequent engagement of said mechanism with the threaded surface of the plunger to achieve precise control during final pressurization of the balloon catheter. In addition, there is provided an improved and novel pressure indicating means for providing the physician with an analog readout of the pressure being applied to the balloon catheter.

Catheter system providing step reduction for postconditioning

CATHETER WITH TAPERED MEHRKAMMER BALLOON

Self-occluding catheter

Controlled failure balloon catheter assemblies

Drainage appliance for body waste

A drainage appliance includes a distal portion with a distensible retention cuff for retaining the distal portion in the rectum, intestinal or urinary tract. Cuff distension is controlled by a combination of: (a) a resiliently deformable device for urging distension of the cuff; (b) a fluid-containing chamber of variable size; and (c) a fluid-transfer damper for restricting fluid flow with respect to the chamber when the chamber changes size.

Balloon-equipped endoscopic devices and methods thereof

An endoscopy system including a balloon-equipped endoscope including a balloon which is configured for slidable frictional engagement with an interior wall of a body passageway and axial stretching of the interior wall when inflated to a slidable frictional engagement pressure and displaced axially along the body passageway and a balloon inflation subsystem operative to selectably inflate the balloon to the slidable frictional engagement pressure.

Drug delivery medical devices

Medical devices for delivering a bioactive agent and methods of use thereof are provided. The medical devices include micro-needles integrated within a balloon of a catheter. The balloon can include dimples, cavities or a variable thickness membrane in which the micro-needles are integrated.

Apparatus and methods for treating obstructions within body lumens

Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.

Balloon Catheter Systems for Delivery of Dry Drug Delivery Vesicles to a Vessel in the Body

Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles, disposed at a suitable location within the balloon or catheter. The reservoir may be installed within the angioplasty balloon, within a lumen in communication with the angioplasty balloon, either as a loose or packed powder or as a film coating. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.

Balloon Catheter Systems for Delivery of Dry Drug Delivery Vesicles to a Vessel in the Body

Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles, disposed at a suitable location within the balloon or catheter. The reservoir may be installed within the angioplasty balloon, within a lumen in communication with the angioplasty balloon, either as a loose or packed powder or as a film coating. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.

Apparatus for preventing over inflation of the retention balloon in medical catheters and airway devices

The body has a fluid inlet port for receiving pressurized fluid and a fluid outlet port connected to the retention balloon. A first passage connects the fluid inlet port and the fluid outlet port. A second passage in the body is connected to the balloon fluid return path and is at the pressure of the retention balloon. A valve prevents fluid flow through the first passage when actuated. The valve includes a pressure-responsive member movable to a position to obstruct fluid flow in response to fluid pressure in the second passage exceeding the predetermined level. Flexible means such as a membrane defines a normally open portion of the first fluid passage, which is closed by the moveable means bearing on the membrane when pressure exceeding the predetermined level actuates the valve.

Inflatable medical devices

An inflatable structure for use in biological lumens and methods of making and using the same are disclosed. The structure can have an inflatable balloon encircled by a shell. The shell can have proximal and distal tapered necks, longitudinally-oriented flutes, and apertures at the proximal and distal ends of the shell. The apertures can be recessed in the flutes in the necks. The shell can also have fiber reinforced walls.

Balloon-equipped endoscopic devices and methods thereof

An endoscopy system including a balloon-equipped endoscope including a balloon which is configured for slidable frictional engagement with an interior wall of a body passageway and axial stretching of the interior wall when inflated to a slidable frictional engagement pressure and displaced axially along the body passageway and a balloon inflation subsystem operative to selectably inflate the balloon to the slidable frictional engagement pressure.

INFLATABLE INTRAUTERINE BALLOON

Disclosed herein are inflatable balloon apparatuses for use in stopping massive blood flow from a uterine wall due trauma or disease. Also disclosed is a method for using the apparatuses. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. An inflatable balloon apparatus for treating obstetrical hemorrhaging , the apparatus comprising:an inflatable balloon comprising an inner layer and an outer layer, the inner layer being inflatable to an inflated configuration to take on a shape of an obstetrical site to be controlled, the outer layer being positionable against a wall of the obstetrical site to control flow of blood from the wall, wherein in the inflated configuration, the balloon comprises a chamber between the inner layer and the outer layer for receiving flow of blood from the obstetrical site;an insufflation tube coupled to the inner layer of the balloon for communication of a distending medium to inflate the balloon; andan internal drain tube comprising an inserted end and a port at the inserted end, the drain tube being coupled to the chamber of the balloon, the drain tube being configured for draining blood or other fluids from the obstetrical site via the chamber of the balloon.13. The apparatus of claim 12 , wherein the insufflation tube is coaxially disposed within the drain tube at a proximal end of the balloon.14. The apparatus of claim 12 , wherein the insufflation tube comprises a semi-rigid catheter extending into the balloon inner layer claim 12 , the insufflation tube facilitating insertion and removal of the balloon from the obstetrical site.15. The apparatus of claim 14 , wherein the catheter comprises an inner end portion and a series of apertures at the inner end portion for infusing a physiologic fluid into the balloon after insertion of the balloon into the obstetrical site.16. The apparatus of claim 12 , further comprising a pressure control ...

Intragastric volume-occupying device and method for fabricating same

Intragastric volume-occupying devices and methods for treating obesity are provided. The devices, which are inflated by carbon dioxide, include an aluminum or silicon oxide barrier layer providing carbon dioxide retention and an alkylene vinyl alcohol polymer layer providing structural integrity in vivo.

STRETCH VALVE BALLOON CATHETER AND METHODS FOR PRODUCING AND USING SAME

A safety balloon catheter includes a catheter having a stretch valve, a connector, a balloon inflated with an inflation fluid, a hollow inflation lumen extending through the catheter to the balloon and conveying inflation fluid thereto and therefrom, a hollow second lumen, and a balloon drainage port fluidically connecting the balloon to the second lumen. The stretch valve has a hollow base fixed in the second lumen at a proximal catheter end and shaped to permit a fluid therethrough and a hollow plug slidably positioned in the second lumen at a given distance from the base to, in a steady state, prevent inflation fluid from passing through the drainage port and, when actuated, slide within the second lumen to permit inflation fluid to pass through the drainage port and into the second lumen. The connector connects the base and the plug and has a length greater than the given distance. 1 a drain lumen extending through the shaft and shaped to drain fluid adjacent the distal tip proximally through the drain lumen and out the drain end;', 'a distal hollow balloon portion defining a balloon interior and having at least one inflation port fluidically connected to the balloon interior, the balloon portion inflating outwardly to a diameter greater than the outer diameter of the shaft when inflated with inflation fluid;', 'at least one inflation lumen parallel to the drain lumen and fluidically connected to the balloon interior through the at least one inflation port, the at least one inflation lumen shaped to inflate the balloon interior with the inflation fluid; and', 'a balloon drainage port fluidically connecting the balloon interior to the drain lumen; and, 'a flexible, multi-lumen shaft having an outer diameter, a distal tip, and a proximal catheter end with a drain end, the multi-lumen shaft defining a body removably disposed in the balloon drainage port and shaped to prevent fluid from passing through the balloon drainage port when disposed in the balloon drainage ...

ARRANGEMENT FOR IMPLEMENTING KISSING BALLOONS FOR SIMULATING A BIFURCATED VESSEL, A KIT, A METHOD OF MANUFACTURING THE ARRANGEMENT AND A CATHETER PROVIDED WITH A BUFFER VOLUME

The invention relates to an arrangement () for implementing kissing balloons simulating a bifurcated vessel, comprising a first catheter () having a first inflatable balloon () at or near its distal portion, a second catheter () having a second inflatable balloon () at or near its distal portion, wherein the first catheter comprises a holding element () provided on the said first balloon (), the said holding element () being adapted for: allowing the distal portion of the second catheter () to pass there through; affixing the second catheter () in a proximal vicinity to the first catheter () so that, in use, respective facing surfaces of the inflated first balloon () and the inflated second balloon () touch each other. 1. An arrangement for implementing kissing balloons simulating a bifurcated vessel , comprising a first catheter having a first inflatable balloon at or near its distal portion , a second catheter having a second inflatable balloon at or near its distal portion , wherein the first balloon comprises a holding element , the said holding element being adapted for:(i) allowing the distal portion of the second catheter to pass there through;(ii) affixing the second catheter in a proximal vicinity to the first catheter so that, in use, respective facing surfaces of the inflated first balloon and the inflated second balloon touch each other.2. The arrangement according to claim 1 , wherein the holding element is substantially cylindrically shaped.3. The arrangement according to claim 1 , wherein the holding element comprises a distal portion and a proximal portion claim 1 , and wherein the holding element tapers from the proximal portion towards the distal portion.4. The arrangement according to claim 1 , wherein the holding element is hook-like.5. The arrangement according to claim 1 , wherein the holding element is arranged within 5 cm from the distal end of the first balloon.6. The arrangement according to claim 1 , wherein a transversal dimension of the ...

INTRAGASTRIC DEVICE

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 120-. (canceled)21. An intragastric balloon , comprising:a polymeric wall; anda balloon valve system comprising a self-sealing septum in a retaining structure, wherein the self-sealing septum is configured for piercing by a hollow needle of an inflation catheter, wherein the retaining structure comprises a concentric valve system with a smaller inner cylinder housing the self-sealing septum and a larger outer cylinder housing a material configured to provide compressive forces against a bell-shaped needle sleeve of an inflation catheter for inflation and detachment, wherein the smaller inner cylinder comprises a lip configured for an interference fit with the bell-shaped needle sleeve to provide sealing of the balloon valve system to the inflation catheter sufficient to maintain a seal during inflation of the intragastric balloon, wherein the interference fit is configured to provide detachment of the inflation catheter from the intragastric balloon after inflation of the balloon in vivo is complete, wherein the outer cylinder comprises a head unit comprising a circular lip that is larger than a diameter of the inner cylinder and extends to an outside surface of the intragastric balloon, wherein the circular lip of the head unit is configured for an interference fit with the bell-shaped needle sleeve.22. The intragastric balloon of claim 21 , wherein the polymeric wall comprises a barrier material comprising a layer of nylon and a layer of polyethylene.23. The intragastric balloon of claim 21 , wherein the polymeric wall comprises a barrier material comprising a layer of nylon claim 21 , a layer of polyvinylidene chloride claim 21 , and a layer of polyethylene.24. The intragastric balloon of claim 21 , further comprising a balloon outer container.25. The intragastric balloon ...

Intragastric device

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided.

FLUID CONTAINER REPLACEMENT SYSTEM AND METHOD

A container replacement system for replacing a fluid container with a replacement fluid container, wherein the fluid container contains a cryogenic fluid and is coupled to a pressure line, includes a control valve that vents the cryogenic fluid within the pressure line, a pressure sensor that senses a line pressure of the cryogenic fluid and generates sensor output and a controller that receives sensor output and determines whether to replace the fluid container. If the line pressure is below a threshold line pressure, the controller determines replacing the fluid container is permissible. Contrarily, if the line pressure is above the threshold line pressure, the controller determines replacing the fluid container is not permissible. The container replacement system further includes a GUI that instructs whether replacing the fluid container is permissible. 1. A cryogenic fluid supply system for a cryogenic balloon catheter system including a cryoballoon catheter , the cryogenic fluid supply system comprising:a cryogenic fluid container configured to contain a cryogenic fluid;a pressure line fluidly coupled to the cryogenic fluid container and the cryoballoon catheter, the pressure line configured to selectively deliver the cryogenic fluid to the cryoballoon catheter from the cryogenic fluid container;a vent conduit in fluid communication with the pressure line, the vent conduit including an in-line control valve, the vent conduit configured to selectively vent the cryogenic fluid from the pressure line through the control valve;a pressure sensor configured to sense a line pressure of the cryogenic fluid within the pressure line and to generate a sensor output based thereon; anda controller configured to receive and process the sensor output to determine whether the pressure line is fluidly isolated from the cryogenic fluid container based on the sensor output.2. The cryogenic fluid supply system of claim 1 , wherein the control valve is configured to be manually ...

System and method for the effective, reliable and foolproof delivery of controlled amounts of a medical fluid

A method for using CO 2 as a contrast material in medical imaging procedures is disclosed. The method includes providing a source of pressurized CO 2 . The step of providing includes connecting the source of pressurized CO2 to a compressed gas unit for controlling delivery of the CO 2 . The method also includes regulating pressure of the CO 2 delivered by the compressed gas unit, transmitting the pressurized CO 2 from the compressed gas unit to a control valve assembly for delivery to a patient in controlled dosages, and sequentially processing the CO 2 with the control valve assembly and delivering the CO 2 to the patient as a contrast media.

DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. 1. A method for treating a body lumen stricture , the method comprising:inserting a scope and a balloon catheter with a drug coating into a body lumen such that the balloon catheter is in a stricture in the body lumen;inflating to the balloon catheter to an initial pressure and maintaining the initial pressure until the pressure no longer drops;inflating to a next higher pressure above the initial pressure and maintaining the next higher pressure until the pressure inside the balloon no longer drops;repeating the inflating to the next higher pressure and the maintaining until the lumen is dilated to a desired diameter;keeping the balloon inflated for 1 minute to 7 days to release the drug into tissue and to prevent bleeding;deflating the balloon catheter; andwithdrawing the scope and balloon catheter from the body lumen.2. The method of claim 1 , further comprising claim 1 , prior to the insertion of the balloon into the stricture claim 1 , flushing the body lumen stricture with water claim 1 , saline solution claim 1 , or a water solution comprising at least one water soluble additive.3. The method of claim 1 , wherein the balloon catheter and the scope are positioned side by side.4. The method of claim 1 , wherein the balloon catheter is loaded into the scope.5. The method of claim 1 , wherein the drug coating comprises one or more water-soluble additives and an initial drug load of a therapeutic agent.6. The method of claim 5 , wherein the water-soluble additive is ...

System for deploying a vascular bypass prosthesis

Systems are provided for deploying a vascular prosthesis having at least one stent with an end portion configured to be introduced into a vessel and a sheath connected thereto. The systems include a first expandable balloon for shaping and stabilizing the vascular prosthesis in the vessel, a second expandable balloon for sealing a junction between the end portion of the vascular prosthesis and the vessel, and means for expanding the first and second expandable balloons.

PRESSURE LIMITING MECHANISM FOR FLUID DISPLACEMENT AND PRESSURIZING SYRINGE AND METHOD OF ASSEMBLY

A syringe which has an intended pressure limit. The syringe includes a syringe body, and a pressure-limiting mechanism is disposed inside the syringe body. The pressure-limiting mechanism may comprise a valve body which is spring biased in the syringe body. In one embodiment, the pressure-limiting mechanism is provided in the form the valve assembly having a valve seal which moves into sealing engagement with an internal wall of a valve bore in the syringe housing once the intended pressure limit is reached. In another embodiment, the pressure-limiting mechanism is provided in the form of the valve assembly having a valve seat which moves into sealing or plugged engagement with a valve plug once the intended pressure limit is reached. Regardless of the exact configuration, preferably the syringe is simple, reliable, easy to assembly, and easy to sterilize given its low number of parts. 1. An inflation device configured to pressurize a medical device , said inflation device comprising: a syringe body; a valve assembly disposed inside the syringe body and configured to define a pressure limit of the inflation device.2. An inflation device as recited in claim 1 , wherein the valve assembly comprises a valve spool claim 1 , wherein the valve spool has a central throughbore which defines a fluid passageway through which fluid flows so long as the intended pressure limit of the inflation device has not been reached.3. An inflation device as recited in claim 1 , wherein the valve assembly comprises a valve spool claim 1 , wherein the valve spool comprises a plurality of valve pistons claim 1 , wherein each of the valve pistons has a corresponding valve seal which contactably engages a corresponding internal wall of the syringe body.4. An inflation device as recited in claim 3 , wherein each valve piston of the valve spool is sized differently relative to each other.5. An inflation device as recited in claim 4 , wherein an inner profile of the syringe body is configured to ...

SYSTEMS AND METHODS FOR LOCATING AND/OR CHARACTERIZING INTRAGASTRIC DEVICES

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of tracking and locating the same are provided. 1. A system for electromagnetically locating an intragastric device in three dimensional space , in real time , the system comprising:a) an electromagnetic field generator configured to generate an electromagnetic field;b) a removably attachable inductive reference sensor adapted to be removably attached to a body positioned within the electromagnetic field, whereby a reference sensor signal is generated and the reference sensor signal carries reference sensor position information associated with a position of the reference sensor within the electromagnetic field at an instance in time;c) a swallowable target sensor adapted to be positioned within the electromagnetic field, whereby a target sensor signal is generated and the target sensor signal carries target sensor position information associated with a position of the target sensor within the electromagnetic field at the instance in time; i) the processor processes the reference sensor signal so as to create one or more reference indicia associated with the position of the reference sensor at the instance in time; and', 'ii) the processor processes the target sensor signal so as to create one or more target indicia associated with the position of the target sensor at the instance in time; and, 'd) a processor adapted to be in electronic communication with the reference sensor and the target sensor, so as to receive the reference sensor signal and the target sensor signal; wherein'}e) a display adapted to be in electronic communication with the processor and configured to display the one or more reference indicia and the one or more target indicia.2. The system of claim 1 , wherein the instance in time comprises a plurality of instances in time.3. The system of claim 2 , whereina) the processor iteratively processes the received reference sensor signal ...

INTRAGASTRIC DEVICE

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 1. An intragastric balloon comprising:an initial fill gas, wherein the initial fill gas consists essentially of inert gas;a valve system configured for introducing the initial fill gas into the balloon in vivo; and{'sub': '2', 'sup': '2', 'a polymeric wall comprising one or more layers, wherein the polymeric wall is configured to have, under in vivo conditions, a permeability to COof more than 10 cc/m/day, and wherein the polymeric wall is configured such that, in vivo, the balloon is configured to gain in volume and in pressure during a useful life of the intragastric balloon when filled with the initial fill gas.'}2. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a three layer CObarrier material consisting of nylon/polyvinylidene chloride/polyethylene.3. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a three layer CObarrier material consisting of nylon/ethylene vinyl alcohol/polyethylene.4. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a two layer CObarrier material consisting of nylon/polyethylene and no additional CObarrier material.5. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a four layer CObarrier material consisting of nylon/ethylene vinyl alcohol/polyvinylchloride/polyethylene.6. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a nylon layer claim 1 , a polyvinylidene chloride layer claim 1 , and a polyethylene layer.7. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a nylon layer claim 1 , a polyvinylidene chloride layer claim 1 , a polyethylene layer claim 1 , and an ethylene vinyl alcohol layer.8. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a nylon layer claim 1 , a ...

MEDICAL DEVICE FOR PROVIDING PORT-LIKE ACCESS TO A MAMMALIAN URINARY SYSTEM AND METHODS OF INSERTING AND UTILIZING THE SAME

A medical device for providing direct port-like endoscopic access to the urinary bladder, or other orifice, of a patient and a method of utilizing and inserting the medical device. The medical device can include a hollow tube with a main channel and a separate channel, a cap with an inflation port and a hollow flexible stem fluidly connecting the inflation port and the separate channel. A method can include inserting a needle above the pubic symphysis of a mammal, threading a guide wire through the needle, removing the needle and inserting the medical device. The method can optionally include determining measuring the depth between the skin surface of the patient's suprapubic region and urinary bladder. 1. A medical device comprising:a continuous hollow tube, the length sized for spanning the distance between an exterior surface of a mammal's back and the mammal's pelvis of its kidney, the hollow tube having an open proximal end and an open distal end;a first cap having a top surface and a bottom surface, the first cap being operatively configured for securely attaching to the proximal end of the tube;a hollow flexible stem fluidly connecting the first cap and the proximal end of the hollow tube so that liquid may pass into the bottom surface of the first cap, through the hollow flexible stem and into a separate channel within the hollow tube; andan inflation port on the bottom surface of the cap.2. The medical device of wherein the continuous hollow tube has a diameter between 10 french and 40 french and the proximal end of the hollow tube is longitudinally more rigid than the distal end.3. The medical device of wherein the first cap covers the open proximal end of the tube when securely attached to the proximal end of the tube and the bottom surface of the cap is recessed within the proximal end of the tube upon secure attachment.4. The medical device of wherein the fluidly separate channel runs from the proximal end of the hollow tube toward the distal end of the ...

RECTAL DRAIN APPLIANCE

A rectal drainage appliance is disclosed comprising a tubular element having an inflatable balloon at a distal end for anchoring the appliance in the rectum. The appliance includes one or more of: (i) first and second auxiliary lumens communicating with the inflatable balloon to provide independent inflation and pressure monitoring paths coupled to the balloon; (ii) a pressure state indicator defined by a mechanical element configured to flip between first and second states or shapes responsive to sensed pressure; and (iii) a collapsible auxiliary lumen larger than the inflation lumen, and configured to permit admission of irrigation fluid. The pressure state indicator may also be used in intestinal drains. 1. A rectal drainage appliance comprising:a tubular element defining a drain passage for effluent from a rectum;an inflatable balloon at a first distal end of the tubular element for insertion into the rectum;a first auxiliary lumen communicating with the inflatable balloon, the first auxiliary lumen being substantially non-collapsing and having a first cross-section area; anda collapsing auxiliary lumen extending to the distal end of the tubular element, the collapsing auxiliary lumen having a second cross-section area that is (i) larger than the first cross section area when the collapsing auxiliary lumen is in a distended state, and (ii) not greater than the first cross-section area when the collapsing auxiliary lumen is in a collapsed state.2. The rectal drainage appliance of claim 1 , wherein the collapsing auxiliary lumen is an irrigation lumen.3. The rectal drainage appliance of claim 1 , wherein the first auxiliary lumen and the collapsing auxiliary lumen are attached to claim 1 , or integrally molded with claim 1 , the tubular element.4. The rectal drainage appliance of claim 1 , wherein the first auxiliary lumen or the collapsing auxiliary lumen extends claim 1 , over at least a part of its length claim 1 , within the tubular element.5. The rectal ...

ENDORECTAL BALLOON WITH GAS LUMEN AND STOPPER

A prostate immobilizing balloon having a central seating area that on full inflation cups the prostate to hold it during treatment is combined with a gas lumen, a locking member and one or more fiducial markers. Methods of using same are also provided. 1. A prostate immobilizing balloon , said balloon comprising:i) an inflatable balloon having a proximal end and a distal end;ii) said balloon further comprising a depressed central seating area when fully inflated, wherein said central seating area retains the prostate in a seated position in said central seating area when said balloon is fully inflated and in use in a rectum of a patient;iii) a first lumen communicating with an interior of said balloon, said first lumen having a closable valve;iv) a locking member around said first lumen, said locking member being movable between a locked position and an unlocked position, said locking member having an inner surface suitable for gripping said first lumen when said locking member is in said locked position;v) a second lumen extending from past said proximal end of said balloon to past said distal end of said balloon, said second lumen having a closed distal tip and one or more ports adjacent said closed distal tip and distal to said balloon; andvi) one or more fiducial markers on a surface thereof.2. The prostate immobilizing balloon of claim 1 , said locking member having a hemispherical distal surface for comfortably positioning adjacent an anus when in use.3. A method of treating prostate cancer by external beam radiation therapy (XRT) claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'a) inserting a prostate immobilizing balloon of into a rectum of a patient with a cancerous prostate;'}b) allowing rectal gas to exit the rectum via said one or more ports until no further exiting gas is evident;c) inflating said balloon sufficiently to immobilize said prostate in said central seating area;d) determining the position of said one or more fiducial ...

METHOD AND APPARATUS FOR INFLATING AND DEFLATING BALLOON CATHETERS

A system and method for controlling the inflation, ablation, and deflation of a balloon catheter. The system includes a balloon catheter, a console, a pressurized gas or liquid inflation source, and an umbilical system to deliver pressurized coolant to the balloon catheter. The system may include controller that monitors the amount of pressure and volume within the balloon catheter. During inflation, the pressure and/or volume of fluid within the balloon is maintained at a target amount in order to provide sufficient mechanized pressure against the desired target region. The system limits the inflation pressure such that a safe quantity of gas would be released should a leak occur. If the amount falls below a certain threshold level, gas or fluid egress is presumed and the inflation process is halted. 1. A method of ablating tissue , the method comprising:delivering inflation fluid to an expandable treatment element of a medical device at a first target flow rate;positioning the medical device proximate an ablation site;delivering inflation fluid to the expandable treatment element at a second target flow rate that is greater than the first target flow rate; andablating the tissue with the expandable treatment element.2. The method of claim 1 , wherein the inflation fluid is transferred to the expandable treatment element under a fixed flow pressure.3. The method of claim 1 , wherein the medical device includes at least one of a temperature sensor claim 1 , a pressure sensor claim 1 , and a flow rate sensor.4. The method of claim 3 , further comprising:detecting a flow rate of the inflation fluid to the expandable treatment element; andadjusting the flow rate of the inflation fluid to the expandable treatment element based on the detected flow rate.5. The method of claim 4 , wherein the flow rate of the inflation fluid to the expandable treatment element is adjusted automatically by at least one valve claim 4 , the at least one valve being in communication with a ...

Balloon Catheter Systems for Delivery of Dry Drug Delivery Vesicles to a Vessel in the Body

Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon. 1. A method for delivery of drugs or therapeutic agents to a vessel within a body of a patient , said method comprising the steps of:providing a catheter system comprising:a balloon catheter comprising a catheter body with a distal end adapted for insertion into vasculature of a patient, a porous balloon disposed on the distal end, a proximal end adapted for connection to a fluid source, and a lumen extending from the proximal end to the balloon;a storage chamber with a reservoir of dry drug delivery vesicles;reconstituting the drug delivery vessels in the storage chamber to create a suspension of reconstituted drug delivery vesicles of a size;wherein the porous balloon has pores of predetermined size; andthe predetermined size of the pores is 2.5 to 125 times the size of the reconstituted drug delivery vesicles; andforcing the suspension of reconstituted drug delivery vesicles through the lumen of the catheter and the porous balloon and into body tissue surrounding the balloon.2. A method for delivery of drugs or therapeutic agents to a vessel within a body of a patient , said method comprising the steps of:providing a catheter system comprising:a balloon catheter comprising a catheter body with a distal end adapted for insertion into vasculature of a patient, a porous balloon disposed on the distal end, a proximal end adapted for connection to a fluid source, and a lumen extending from the proximal end to the balloon;a storage ...

Balloon dilatation system

Provided is a balloon dilatation system, which includes a signal collecting module, a main controller, a pressurization module, a pressure relief module, a first pressure sensor, a flow rate sensor, a balloon catheter and a balloon. The signal collecting module is electrically connected to the main controller, and is configured to collect a control signal and send the control signal to the main controller; the main controller is electrically connected to the pressurization module and the pressure relief module; the pressurization module is connected to the balloon through the balloon catheter; the pressure relief module is connected to the balloon through the balloon catheter; the first pressure sensor is arranged on the balloon catheter and is configured to monitor a first liquid pressure of the balloon; the flow rate sensor is arranged on the balloon catheter and is configured to monitor a liquid flow rate of the balloon catheter.

INFLATABLE MEDICAL DEVICES

An inflatable structure for use in biological lumens and methods of making and using the same are disclosed. The structure can have an inflatable balloon encircled by a shell. The shell can have proximal and distal tapered necks, longitudinally-oriented flutes, and apertures at the proximal and distal ends of the shell. The apertures can be recessed in the flutes in the necks. The shell can also have fiber reinforced walls. 1. An apparatus for performing a medical procedure in a vessel for transmitting a flow of fluid , comprising:a shaft;an inflatable perfusion balloon supported by the shaft and comprising a plurality of inflatable cells in a single cross-section bounding an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition; anda valve for controlling the fluid flow within the internal passage.2. The apparatus of claim 1 , wherein the valve is positioned within the internal passage.3. The apparatus of claim 1 , wherein the balloon includes an opening in fluid communication with the internal passage claim 1 , and the valve is positioned for controlling flow through the opening.4. The apparatus of claim 3 , wherein the valve comprises a flap.5. The apparatus of claim 1 , wherein the valve comprises a plurality of flaps.6. The apparatus of claim 1 , wherein the valve comprises a flap connected to at least one of the inflatable cells.7. The apparatus of claim 6 , wherein the flap extends between an inner surface of the at least one inflatable cell and a tube extending within an internal passage of the balloon.8. The apparatus of claim 7 , wherein the valve comprises a plurality of flaps adapted for blocking flow in the internal passage by spanning between an interior surface of the inflatable cells and the tube.9. The apparatus of claim 1 , further including a shell having a shell aperture claim 1 , the valve adapted for selectively blocking the shell aperture for selectively communicating fluid from ...

THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. 1. (canceled)2. A method for delivering Exenatide into the wall of the small intestine , the method comprising:swallowing a drug delivery device comprising a capsule, an actuator having a first configuration and a second configuration and a Exenatide preparation operably coupled to the actuator, the Exenatide preparation comprising a therapeutically effective dose of Exenatide, the preparation being contained within the capsule in the first configuration and advanced out of the capsule and into the lumen wall in the second configuration so as to deliver the Exenatide preparation into the lumen wall; andactuating the actuator responsive to a condition in the small intestine to deliver the Exenatide preparation into the wall of the small intestine.3. The method of claim 2 , wherein the condition is a selected pH.4. The method of claim 3 , wherein the pH is above about 7.1.5. The method of claim 2 , wherein the dose of Exenatide is in the preparation is in a range from about 1 to 10 μg. ...

SMART 3-WAY VALVE WITH HIGH AND LOW PRESSURE SENSING

Apparatus and methods are provided for managing delivery of fluid into a vessel. A balloon catheter with a 3-way valve is introduced into an occluded vessel. The 3-way valve permits fluid, such as a contrast dye, to be injected into the vessel lumen. The valve is also configured to permit the balloon portion of the catheter to be inflated by means of the same lumen used to inject the contrast dye into the vessel. Bloodstream pressure can also be measured before and after dilation to confirm the procedure was successful. This apparatus and method provides for a quick, safe, and reliable treatment of an occluded vessel, among other things and works with known and later developed systems. 1. A valve unit configured for directing a high pressure fluid to a balloon that comprises a balloon lumen , and configured for directing low pressure fluid to a vascular lumen , the valve unit comprising:(i) a 3-way valve operably linked with a high pressure fluid port, a low pressure fluid port, and an exit port; and 'wherein the 3-way valve has a first position that is configured to receive the high pressure fluid via the high pressure fluid port,', '(ii) a high pressure fluid input port, a low pressure fluid port, and an exit port;'}wherein the 3-way valve has a second position that is configured to receive the low pressure fluid via the low pressure fluid port,wherein the 3-way valve is configured to transmit the high pressure fluid to the exit port, and is configured to transmit the low pressure fluid to the exit port; andwherein the valve has a third position that is configured to simultaneously prevent flow of high pressure fluid from the high pressure fluid port to the exit port and flow of low pressure fluid from the low pressure port to the exit port,(iii) a high pressure sensor that detects pressure of the high pressure fluid, wherein the high pressure sensor is segregated from and not exposed to the low pressure fluid; and(iv) a low pressure sensor that detects pressure ...

DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. 1. A method for treating a body lumen stricture , the method comprising:flushing the body lumen stricture with water, saline solution, or a water solution comprising at least one water soluble additive, wherein the body lumen stricture is a urethral stricture or a benign prostatic hyperplasia (BPH) stricture;inserting a balloon catheter with a drug coating comprising an initial drug load of a therapeutic agent into a body lumen such that the balloon catheter is in the body lumen stricture, the balloon catheter comprising an elongated balloon having a main diameter, the elongated balloon comprising at least one neck section, the balloon comprising a first main section and a second main section on opposite sides of the neck section;inflating the balloon catheter such that the first main section of the balloon catheter is in the prostatic urethra, the second main section of the balloon catheter is in the bladder, and the neck section is in the bladder neck, until the stricture in the body lumen is dilated to a desired diameter, wherein the at least one neck section comprises an inflated diameter that is smaller than the main diameter when the balloon is inflated, during the inflating the inflated diameter of the neck section is the smallest diameter of the balloon catheter between the first main section and the second main section, during the inflating the inflated diameter of the neck section is greater than a diameter of the neck section prior to the inflation, and the ...

DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. 1. A method for treating a body lumen stricture , the method comprising:inserting a balloon catheter into a body lumen such that the balloon catheter is in the body lumen stricture, the balloon catheter comprising an elongated balloon having a main diameter, the elongated balloon comprising at least one neck section, the balloon comprising a first main section and a second main section on opposite sides of the neck section;inflating the balloon catheter in the body lumen stricture until the stricture in the body lumen is dilated to a desired diameter, wherein the at least one neck section comprises an inflated diameter that is smaller than the main diameter when the balloon is inflated, during the inflating the inflated diameter of the neck section is the smallest diameter of the balloon catheter between the first main section and the second main section, during the inflating the inflated diameter of the neck section is greater than a diameter of the neck section prior to the inflation, and the at least one neck section comprises an area of reduced compliance during inflation relative to the first main section and the second main section;deflating the balloon catheter; andwithdrawing the balloon catheter from the body lumen.2. The method of claim 1 , wherein the body lumen stricture comprises a stricture in a vascular lumen claim 1 , a nonvascular lumen claim 1 , a coronary artery claim 1 , a peripheral artery claim 1 , a urethra claim 1 , a ureter claim 1 , a ...

DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. 1. A balloon catheter comprising:an elongated balloon comprising at least one neck section, the balloon comprising a first main section and a second main section on opposite sides of the neck section, the at least one neck section comprising an area of reduced compliance during inflation relative to the first main section and the second main section;wherein the first main section and second main section have a main diameter when the balloon is inflated, the at least one neck section comprises an inflated diameter that is smaller than the inflated main diameter of the first and second sections, the inflated diameter of the neck section is the smallest diameter of the balloon catheter between the first main section and the second main section when the balloon is inflated, and the inflated diameter of the neck section is greater than an uninflated diameter of the neck section.2. The balloon catheter of claim 1 , further comprising a single inflation lumen that provides simultaneous inflation of the first main section claim 1 , the neck claim 1 , and the second main section claim 1 ,3. The balloon catheter of claim 1 , wherein the at least one neck section comprises a reinforcing material around a circumference of the neck section to reduce compliance of the neck section during inflation of the balloon.4. The balloon catheter of claim 3 , wherein the reinforcing material comprises a suture claim 3 , monofilament claim 3 , or multifilament claim 3 , wherein the reinforcing ...

SYSTEM AND METHOD FOR THE EFFECTIVE, RELIABLE AND FOOLPROOF DELIVERY OF CONTROLLED AMOUNTS OF A MEDICAL FLUID

A method for using COas a contrast material in medical imaging procedures is disclosed. The method includes providing a source of pressurized CO. The step of providing includes connecting the source of pressurized CO2 to a compressed gas unit for controlling delivery of the CO. The method also includes regulating pressure of the COdelivered by the compressed gas unit, transmitting the pressurized COfrom the compressed gas unit to a control valve assembly for delivery to a patient in controlled dosages, and sequentially processing the COwith the control valve assembly and delivering the COto the patient as a contrast media. 15-. (canceled)6. A method for using COas a contrast material in medical imaging procedures , comprising:{'sub': 2', '2', '2, 'providing a source of pressurized CO, wherein the source of pressurized COis a cartridge filled with compressed CO;'}{'sub': 2', '2', '2, 'connecting the source of pressurized COto a compressed gas unit for controlling delivery of the CO, and the compressed gas unit includes a pressure regulator outputting COat a selected level of pressure;'}{'sub': '2', 'regulating pressure of the COdelivered by the compressed gas unit; and'}{'sub': '2', 'transmitting the pressurized COfrom the compressed gas unit to a control valve assembly for delivery to a patient as a contrast media in controlled dosages patient as a contrast media.'} This application is a continuation in part of U.S. patent application Ser. No. 13/857,448, filed Apr. 5, 2013, entitled “Portable Medical Gas Delivery System”, which is currently pending, which is a continuation in part of U.S. patent application Ser. No. 13/068,680, filed May 17, 2011, entitled “Apparatus and Process for Producing CO2 Enriched Medical Foam”, which is currently pending, which is a continuation in part of U.S. patent application Ser. No. 12/652,845, filed Jan. 8, 2010, entitled “Portable Medical Gas Delivery System”, which is abandoned, which is a continuation in part of U.S. patent ...

SYSTEM FOR EFFECTING AND CONTROLLING OSCILLATORY PRESSURE WITHIN BALLOON CATHETERS FOR FATIGUE FRACTURE OF CALCULI

A dynamic balloon angioplasty system for applying a dynamic pressure to fracture hardened materials embedded within an elastic conduit. The system having a pressure source system outputting at least a first predetermined pressure from a pressure source outlet, and an angioplasty unit fluidly coupled to the pressure source outlet receiving at least the first predetermined pressure. The angioplasty unit having an angioplasty inflation device, an angioplasty balloon connector, and an oscillating mechanism selectively actuated to output a plurality of pressure pulses to the angioplasty balloon via a fluid communication path. A control system is configured to determine an optimal hydraulic pressure oscillation frequency and amplitude for a given procedure and output a control signal to the oscillating mechanism, and monitor a pressure signal to detect fracture of the hardened material within the elastic conduit or system failure or leakage. 1. A dynamic balloon angioplasty system for applying a dynamic pressure to fracture or modify hardened materials embedded within an elastic conduit , the dynamic balloon angioplasty system comprising:a pressure source system configured to output at least a first predetermined pressure from a pressure source outlet;an angioplasty unit being fluidly coupled to the pressure source outlet to receive at least the first predetermined pressure, the angioplasty unit having an angioplasty inflation device and a balloon connector operably coupled to and extending from the angioplasty inflation device, the balloon connector being configured to be connectable to an angioplasty balloon for delivering a plurality of pressure pulses to the angioplasty balloon;an oscillating mechanism being selectively actuated to receive pressure from the pressure source outlet and output the plurality of pressure pulses to the angioplasty balloon via a fluid communication path;a pressure transducer operably coupled to the fluid communication path, the pressure ...

Method of Using an Intra-Esophageal Balloon System

A method is disclosed for selective inflation of an inflatable body, such as a balloon, received through an oral cavity and into the esophagus of a patient. The inflatable body is operably coupled to a pressurized fluid source. The inflatable body has a relatively flexible portion and a relatively inflexible portion. When pressurized fluid is delivered to the body to inflate the body, the flexible portion expands more than the inflexible portion, resulting in asymmetrical expansion and movement of the esophagus away from the ablation site to avoid accidental injury while performing a procedure on the patient's left atrium. This movement may be opposite from or directly away from the heart or, alternatively, may be sideways relative to the heart to a location in which the esophagus is interposed between the ablation site and the phrenic nerve.

INFLATABLE COVERS FOR TRANSESOPHAGEAL ECHOCARDIOGRAPHY TRANSDUCER PROBES

A flexible cover for a probe having an ultrasound emitting tip that includes an inflatable portion, wherein the inflatable portion further includes a first reservoir, wherein the first reservoir is adapted to fit over the ultrasound emitting tip of the probe, and wherein the first reservoir is adapted to receive a first predetermined volume of fluid; a second reservoir adjacent to the first reservoir, wherein the second reservoir is adapted to receive a second predetermined volume of fluid; and a divider for completely separating the first reservoir from the second reservoir; and a collar connected to or formed integrally with the inflatable portion, wherein the collar is operative to seal the inflatable portion against the probe. 1. A cover for a probe having an ultrasound emitting tip , comprising: (i) a first reservoir, wherein the first reservoir is adapted to fit over the ultrasound emitting tip of the probe, and wherein the first reservoir is adapted to receive a first predetermined volume of fluid;', '(ii) a second reservoir adjacent to the first reservoir, wherein the second reservoir is adapted to receive a second predetermined volume of fluid; and', '(iii) a divider for completely separating the first reservoir from the second reservoir; and, '(a) an inflatable portion, wherein the inflatable portion further includes(b) a collar connected to or formed integrally with the inflatable portion, wherein the collar is operative to seal the inflatable portion against the probe.2. The probe cover of claim 1 , further comprising a first fluid conduit connected to the first reservoir.3. The probe cover of claim 2 , further comprising a first stopcock connected to the first fluid conduit.4. The probe cover of claim 1 , further comprising a second fluid conduit connected to the second reservoir.5. The probe cover of claim 4 , further comprising a second stopcock connected to the second fluid conduit.6. The probe cover of claim 1 , wherein the first predetermined ...

INTEGRATED BALLOON CATHETER INFLATION SYSTEM

An inflation system having two pressure vessels integrated into a balloon catheter. A pressurized chamber and a vacuum chamber are integrally attached to proximal end of the balloon catheter and activated by a common valve or switch. Pressure or vacuum is selectively transmitted to the balloon depending on the valve/switch position. The working fluid may be air, or a combination of air and saline with an intermediate piston/cylinder assembly. The balloon catheter may be a part of a heart valve delivery system with a balloon-expandable heart valve crimped onto the balloon. 1. A balloon catheter system having an integrated inflation subsystem , comprising:a manifold having internal passages;a pressurized vessel integrated with an inflation port in the manifold;a balloon catheter having a balloon on a distal end in fluid communication with an inflation lumen extending through the catheter;a balloon port in the manifold in fluid communication with the balloon catheter inflation lumen; anda control valve on the manifold configured to selectively open and close fluid communication between the balloon port and the inflation port so that a positive pressure differential from the pressurized vessel inflates the balloon.2. The system of claim 1 , wherein the balloon catheter system is part of a prosthetic heart valve delivery system including a balloon-expandable heart valve crimped onto the balloon.3. The system of claim 1 , wherein the pressurized vessel is permanently attached to the manifold.4. The system of claim 3 , wherein the pressurized vessel is attached to the manifold in a manner selected from the group consisting of adhesion and thermal welding.5. The system of claim 1 , further including a vacuum vessel integrated with a vacuum port in the manifold claim 1 , wherein the control valve is also configured to selectively open and close fluid communication between the balloon port and the vacuum port so that a negative pressure differential from the vacuum vessel ...

Ostomy Device, Apparatus, and System

Devices for insertion into a stoma formed in a patient's body are provided, comprising a tube having distal and proximal ends and defining a path for movement of waste. To retain the device in the stoma and seal the stoma, the tube includes a retention mechanism located on the distal end and/or a sealing mechanism extending along a length of the tube between the proximal and distal ends. Collection apparatus for collecting waste from a patient's body also are provided, comprising a waste pouch and a connector for connecting the collection apparatus to a device inserted into a stoma. Additionally, waste collection systems for collecting waste from a patient's body are provided, comprising a tube for insertion into a stoma and a waste pouch. Each system may comprise a separate tube and waste pouch or the tube and waste pouch may be formed as an integral, inseparable component. 1. A device for insertion into a stoma formed in a body of a patient , the device defining an axial direction , the device having a distal end and a proximal end spaced apart along the axial direction , the device comprising:a tube extending along the axial direction from the distal end to the proximal end, the tube defining a path for movement of waste; anda sealing mechanism extending axially along a length of the tube between the proximal end and the distal end of the tube, the sealing mechanism having an insertion position and a sealing position,wherein the sealing mechanism expands against a surface of the stoma in the sealing position.2. The device of claim 1 , wherein the sealing mechanism is an inflatable sealing balloon claim 1 , and wherein the sealing balloon is deflated in the insertion position claim 1 , and wherein the sealing balloon is inflated in the sealing position.3. The device of claim 2 , wherein the sealing balloon is a thin-wall claim 2 , high-volume claim 2 , low-pressure cuff.4. The device of claim 1 , wherein the sealing balloon has an inflated diameter and the tube ...

System and method for inflating a cryoablation balloon catheter

A system for inflating a cryogenic ablation catheter balloon, the system comprising a fluid source containing a fluid in a liquid state, a first supply line fluidly coupled to the fluid source and configured to be fluidly coupled to an internal space within the cryogenic ablation catheter balloon, the first supply line including an inline multi-stage pressure regulating system. The multi-stage pressure regulating system includes a first stage configured to cause the fluid to transition from the liquid state to a gas state, and a second stage downstream of the first stage configured to maintain the fluid downstream of the second stage at a pressure corresponding to an inflation pressure of cryogenic ablation catheter balloon.

INTRAGASTRIC VOLUME-OCCUPYING DEVICE AND METHOD FOR FABRICATING SAME

Intragastric volume-occupying devices and methods for treating obesity are provided. The devices, which are inflated by carbon dioxide, include an aluminum or silicon oxide barrier layer providing carbon dioxide retention and an alkylene vinyl alcohol polymer layer providing structural integrity in vivo. 1. An intragastric balloon system comprising a composite wall structure configured to maintain a COleak rate of less than or equal to 40 cc/m/day at 37° C. , wherein the composite wall structure comprises:a supporting film structure having a Young's Modulus of 500 Mpa or greater;{'sub': 2', '2, 'a first CObarrier layer configured such that its CObarrier properties are not substantially affected by exposure to humidity levels within the gastric environment or within a central lumen of the balloon; and'}{'sub': 2', '2, 'a second CObarrier layer configured such that its CObarrier properties are not substantially affected by mechanical forces during processing, compacting, or application of external gastric pressures.'}2. The intragastric balloon system of claim 1 , wherein the first CObarrier layer comprises a silicon dioxide layer having a thickness of from about 100 Åto about 800 Å.3. The intragastric balloon system of claim 1 , wherein the second CObarrier layer comprises an ethylene vinyl alcohol layer having a thickness of at least about 2 microns.4. The intragastric balloon system of claim 1 , wherein the first CObarrier layer comprises a silicon dioxide layer having a thickness of from about 100 Å to about 800 Å and the second CObarrier layer comprises an ethylene vinyl alcohol layer having a thickness of at least about 2 microns.5. The intragastric balloon system of claim 4 , wherein the supporting film structure comprises a polyethylene terephthalate layer.6. The intragastric balloon system of claim 5 , wherein the silicon dioxide layer is provided as a coating on one side of the polyethylene terephthalate layer.7. The intragastric balloon system of claim 6 , ...

BALLOON WITHIN BALLOON CATHETER SYSTEM AND METHODS OF USE

A drug delivery system is described. The system has a first fluid delivery reservoir and a second fluid delivery reservoir. The first reservoir is separately controllable from the second reservoir. The first reservoir and second reservoir are attached to a manifold having a first solution channel in fluid communication with the first reservoir and a second solution channel in fluid communication with the second reservoir. The manifold is connected to a catheter having a first lumen in fluid communication with the first solution channel and a second lumen in fluid communication with the second solution channel. The catheter has a first balloon in fluid communication with the first lumen and a second balloon in fluid communication with the second lumen. The first balloon is located within the second balloon. The first balloon is not in fluid communication with the second balloon and the second balloon is perforated. A method for using the system and a kit containing the system are also described. 1. A drug delivery system , comprising: a first fluid delivery reservoir of a first volume capacity fluid delivery and a second fluid delivery reservoir of a second volume capacity; wherein said first reservoir and said second reservoir are attached to the proximal end of a manifold having a first solution channel in fluid communication with the first fluid delivery reservoir and a second solution channel in fluid communication with the second fluid delivery reservoir; wherein the distal end of the manifold is connected to the proximal end of a catheter comprising a first lumen in fluid communication with the first solution channel of the manifold and a second lumen in fluid communication with the second solution channel of the manifold; the catheter further comprising in the proximity of its distal end a first balloon in fluid communication with the first lumen and a second balloon in fluid communication with the second lumen; wherein the first balloon is located within the ...

Balloon within balloon catheter system and methods of use

A drug delivery system is described. The system has a first fluid delivery reservoir and a second fluid delivery reservoir. The first reservoir is separately controllable from the second reservoir. The first reservoir and second reservoir are attached to a manifold having a first solution channel in fluid communication with the first reservoir and a second solution channel in fluid communication with the second reservoir. The manifold is connected to a catheter having a first lumen in fluid communication with the first solution channel and a second lumen in fluid communication with the second solution channel. The catheter has a first balloon in fluid communication with the first lumen and a second balloon in fluid communication with the second lumen. The first balloon is located within the second balloon. The first balloon is not in fluid communication with the second balloon and the second balloon is perforated. A method for using the system and a kit containing the system are also described.

Stretch Valve Balloon Catheter and Methods for Producing and Using Same

A safety balloon catheter includes a flexible, multi-lumen balloon catheter and a hollow barbell-shaped stretch valve. The balloon catheter has a proximal catheter end, a balloon defining a balloon interior to be inflated with an inflation fluid, a hollow inflation lumen extending through the catheter to the balloon interior and shaped to convey the inflation fluid to and from the balloon interior, and a hollow second lumen parallel to the inflation lumen; and a balloon drainage port fluidically connecting the balloon interior to the second lumen. The stretch valve is shaped to permit a fluid to pass therethrough and positioned in the second lumen to at least partially slide therein such that, in a steady state, a distal barbell end of the stretch valve prevents the inflation fluid from passing through the drainage port and, in an actuated state, the distal barbell end slides within the second lumen to permit the inflation fluid to pass through the drainage port and into the second lumen. 1. A safety balloon catheter , comprising: a proximal catheter end;', 'a balloon defining a balloon interior to be inflated with an inflation fluid;', 'a hollow inflation lumen extending through the catheter to the balloon interior and shaped to convey the inflation fluid to and from the balloon interior;', 'a hollow second lumen parallel to the inflation lumen; and', 'a balloon drainage port fluidically connecting the balloon interior to the second lumen; and, 'a flexible, multi-lumen balloon catheter having shaped to permit a fluid to pass therethrough; and', in a steady state, a distal barbell end of the stretch valve prevents the inflation fluid from passing through the drainage port; and', 'in an actuated state, the distal barbell end slides within the second lumen to permit the inflation fluid to pass through the drainage port and into the second lumen., 'positioned in the second lumen to at least partially slide therein such that], 'a hollow barbell-shaped stretch valve2. ...

Medical device for providing port-like access to a mammalian urinary system and methods of inserting and utilizing the same

A medical device for providing direct port-like endoscopic access to the urinary bladder, or other orifice, of a patient and a method of utilizing and inserting the medical device. The medical device can include a hollow tube with a main channel and a separate channel, a cap with an inflation port and a hollow flexible stem fluidly connecting the inflation port and the separate channel. A method can include inserting a needle above the pubic symphysis of a mammal, threading a guide wire through the needle, removing the needle and inserting the medical device. The method can optionally include determining measuring the depth between the skin surface of the patient's suprapubic region and urinary bladder.

APPARATUS AND METHOD TO STOP BLEEDING

A hemostatic device is provided to stop bleeding at a puncture site on an artery of a patient, the device comprising a transparent flexible band to be wrapped at the site where the bleeding is to be stopped, a curved compression member having an inner peripheral side and possessing a first curved portion in its first half and a second curved portion in its second half, a first balloon provided on the inner peripheral side in the first half of the curved compression member and a second balloon provided on the inner peripheral side in the second half of the curved compression member. The bleeding from a first artery is stopped by compressing the first artery at the puncture site using inflation of the first balloon and blood flow in the first artery is increased by compression of a second artery using inflation of the second balloon. 1. A hemostatic device comprising: a flexible band configured to be wrapped around an individual's arm in which a radial artery and an ulnar artery are located , the flexible band possessing a longitudinal extent that extends in a longitudinal direction;the flexible band including two parts that engage one another when the flexible band is wrapped around the individual's arm in the wrapped state to secure the flexible band to the individual's arm;a compression member connected to the flexible band, the compression member being more rigid than the flexible band, the compression member including a first portion and a second portion that are spaced apart from one another in the longitudinal direction;a first inflatable member connected to the flexible band and possessing an interior, the first portion of the compression member overlying the first inflatable member so that the first inflatable member is positioned between the first portion of the compression member and the individual's arm when the flexible band is wrapped around the individual's arm in the wrapped state;a first lumen in communication with the interior of the first inflatable ...

DELIVERY SYSTEM AND METHOD FOR THE EFFECTIVE, RELIABLE AND FOOLPROOF DELIVERY OF CONTROLLED AMOUNTS OF A MEDICAL FLUID

A method for performing a medical procedure requiring effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams. The method also includes connecting the compressed gas cylinder to an integrated compressed gas unit including a regulator valve assembly positioned between an outlet port and an inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial. A flow control system is secured to the compressed gas unit and the medical grade gas is delivered in precisely controlled amounts by actuating the compressed gas unit and operating the flow control system to deliver the medical grade gas to vasculature of the patient. 1. A method for performing a medical procedure requiring effective , reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient , comprising:providing a compressed gas cylinder having a weight with medical grade gas sealed therein of at least twelve grams and not greater than fifty grams, the compressed gas cylinder including an elongate, generally cylindrical body having an interior chamber accommodating a compressed and sterile medical grade gas therein, wherein said cylindrical body is of a triple washed aluminum construction for holding the medical grade gas within said interior chamber of said cylindrical body under pressure;connecting the compressed gas cylinder to an integrated compressed gas unit including an inlet port to which the compressed gas cylinder is selectively connected and an outlet port in communication with the inlet port, the integrated compressed gas unit also including a regulator valve assembly positioned between the outlet port and the inlet port, wherein the regulator valve assembly includes a press button actuator and regulator adjustment dial; ...

CATHETER DEVICE AND METHOD OF USING THE SAME

Disclosed is a catheter device including a proximal tube having a first part of a first lumen; a distal tube having a second part of the first lumen; a second lumen connecting the proximal tube and the distal tube; wherein the connection comprise an area of discontinuity between the first part and second part; wherein the area of discontinuity comprises a support element configured to resist axial movement of the distal tube relative to the proximal tube and vice versa; and wherein the second lumen is arranged to activate or cause at least one obstruction element to restrict the flow of urine from the proximal tube to the area of discontinuity and to restrict the flow of urine from the area of discontinuity to the distal tube. 1. A catheter device includinga proximal tube having a first part of a first lumen configured for urine to flow therethrough;a distal tube having a second part of the first lumen configured for urine to flow therethrough;a second lumen connecting the proximal tube and the distal tube; wherein the connection comprise an area of discontinuity between the first part and second part of the first lumen; andat least one obstruction element configured to restrict the flow of urine through the area of discontinuity;wherein the area of discontinuity comprises a support element configured to resist axial movement of the distal tube relative to the proximal tube and vice versa; and wherein the area of discontinuity includes an opening operable for urine be flushed periodically out of the catheter.2. The device of claim 1 , wherein the at least one obstruction element comprises at least one of the following: a valve claim 1 , a clamp claim 1 , and a balloon claim 1 , wherein the at least one obstruction element is positioned at a portion of the proximal tube and/or at a portion of the distal tube.3. (canceled)4. The device of claim 2 , wherein the at least one obstruction element is configured to periodically open to release urine (when present) at a ...

Device for Gravity-Driven Control of the Filling Pressure of a Catheter Balloon

Device for gravity-driven, particularly continuous, control of the filling pressure in a balloon catheter (), comprising: a balloon reservoir that is statically loaded with a vertically guided weight guide or stamp () that weighs vertically on the balloon reservoir, wherein said weight guide or stamp is designed to carry vertically arranged and therewith plumb-vertically acting weight elements (), and wherein the balloon reservoir is guided in a cylindrical shell (). 1. A device for gravity-driven , particularly continuous , control of the filling pressure in a balloon catheter , comprising: a balloon reservoir that is statically loaded with a vertically guided weight guide that weighs vertically on the balloon reservoir , wherein said weight guide is configured to carry vertically arranged and therewith plumb-vertically acting weight elements , and wherein the balloon reservoir is guided in a cylindrical shell.2. The device as claimed in claim 1 , further comprising the balloon reservoir is housed in two cup-like half-shells claim 1 , particularly a lower cup-like half-shell and an upper cup-like half-shell claim 1 , wherein said half-shells guide the balloon reservoir in the cylindrical shell.3. The device as claimed in claim 2 , wherein the two cup-like half-shells each comprise an inner surface claim 2 , wherein the balloon reservoir is designed to deploy in a filled state of the balloon reservoir into the inner surfaces claim 2 , and to push the two half-shells apart claim 2 , so as to generate a gap between the half-shells claim 2 , which gap particularly serves as an indicator for the filling pressure in the balloon reservoir adjusted by a user.4. The device as claimed in claim 2 , wherein in a deflated state of the balloon reservoir or when a preset filling pressure is undercut claim 2 , the two cuplike half-shells butt against each other claim 2 , via a collapsed envelope of the balloon reservoir claim 2 , in the cylindrical shell guiding the cup-like half- ...

AUTOMATED BALLOON CATHETER FLUID PURGING SYSTEM

A fluid purging system has a spring-energized relief valve having an inlet port that is coupled to a fluid chamber to receive incoming fluid, and an outlet port through which incoming fluid is relieved. The outlet port is fluidly coupled to a pressurized chamber. The fluid purging system also includes an electro-mechanical pressure switch, and an electrically operated solenoid valve which functions as a pressure exhaust valve. The pressure switch and the solenoid valve are in fluid communication with the pressurized chamber. 1. A fluid purging system , comprising:a spring-energized relief valve having an inlet port that is coupled to a fluid chamber to receive incoming fluid, and an outlet port through which incoming fluid is relieved, the outlet port fluidly coupled to a pressurized chamber;an electro-mechanical pressure switch; andan electrically operated solenoid valve which functions as a pressure exhaust valve;wherein the pressure switch and the solenoid valve are in fluid communication with the pressurized chamber.2. The system of claim 1 , wherein the relief valve has a pre-set cracking pressure set within the range of 30 psig to 550 psig.3. The system of claim 2 , wherein the pressure switch detects fluid leakage from the relief valve and electronically relays a message to a computer controlled system.4. The system of claim 3 , wherein the switching pressure of the pressure switch is designed to be less than the cracking pressure of the relief valve.5. The system of claim 3 , wherein the pressure switch detects pressure rise within the range of 0.10 psig to 25.0 psig.6. The system of claim 1 , wherein the outlet port of the relief valve is connected to a purging tube.7. The system of claim 6 , wherein a purging connector couples the purging tube and the pressurized chamber.8. A catheter system claim 6 , comprising:a catheter assembly having a balloon adjacent its distal end, with a fluid chamber defined adjacent the balloon; and a spring-energized relief ...

Drug Delivery Medical Devices

Medical devices for delivering a bioactive agent and methods of use thereof are provided. The device includes a balloon having micro-needles for delivery of the bioactive agent. 1. A medical device , comprising:a catheter;a balloon disposed at an end of the catheter, the balloon having a first balloon membrane and a second balloon membrane; andmicro-needles disposed in the first balloon membrane, the micro-needles including a hollow area in which a drug can reside, wherein the second balloon membrane is configured to penetrate into the hollow areas so as to push the drug out of the hollow area of the micro-needles for application of the drug to a tissue where the balloon has been positioned and expanded, and wherein the first balloon membrane is in fluid communication with a first fluid path for expansion of the first balloon membrane and the second balloon membrane is in fluid communication with a second fluid path, separate from the first fluid path, for expansion of the second balloon membrane into the hollow area to push the drug out of the hollow area of the micro-needles.2. The device of claim 1 , wherein the first fluid path is operably controlled by a stop cock and a relief valve for maintaining a pressure against the first balloon membrane.3. The device of claim 1 , wherein the second balloon membrane is in fluid communication with the second fluid path for expansion of the second balloon membrane to push the micro-needles into the tissue for delivery of the drug.4. The device of claim 1 , wherein the first balloon membrane is configured to apply a pressure against a vessel wall when a pressure is applied inside of the balloon and the second balloon membrane is configured to push against ends of the micro-needles to cause the micro-needles to penetrate into the tissue.5. The device of claim 1 , wherein the second balloon membrane is responsive to pressure to push the micro-needles into the tissue for delivery of the drug.6. The device of claim 1 , wherein ...

INTRAGASTRIC DEVICE

An implant configured for ingestion by a patient. After the implant has been swallowed by the patient and is disposed within the target location, e.g. the patient's stomach, an inflation subcomponent causes the implant to expand from a compact delivery state to an expanded, volume-occupying, deployed state. In the deployed state the implant creates a sensation of satiety in the patient stomach and thereby aids in limiting food intake and obesity. After a predetermined time a deflation subcomponent is actuated and the implant reduces in size so as to allow it to pass through the remainder of the patient's digestive track. The device may further incorporate tracking and visualization subcomponents, as well as pharmaceutical delivery subcomponents. 1. (canceled)2. (canceled)3. (canceled)4. A swallowable intragastric balloon system comprising:{'sup': 3', '3, 'a balloon comprising a self-sealing valve system attached to a wall of the balloon in a central lumen of the balloon by an adhesive with a shear force greater than about 40 N, the self-sealing valve system comprising a septum, a retaining structure, and a continuous ring, wherein the septum has a durometer that is less than a durometer of the retaining structure, wherein the continuous ring is configured to exert a compressive force on the septum, wherein the balloon has a weight of less than about 15 g, wherein the balloon is configured to have a shape upon full inflation selected from the group consisting of ellipsoid, spheroid, and oblate spheroid, and wherein the balloon is configured to have a volume of from about 90 cmto about 350 cmupon full inflation.'}5. The system of claim 4 , wherein the septum has a durometer of about 20 Shore A to about 60 Shore D claim 4 , and wherein the retaining structure has a durometer of from about 40 Shore D to about 70 Shore D.6. The system of claim 4 , wherein the continuous ring is radio-opaque.7. The system of claim 4 , wherein the balloon is configured to have claim 4 , ...

Device for sealing and drainage of a natural or artificial intestinal outlet

The invention relates to a device for sealing and draining an intestinal outlet, the device comprising an inflatable balloon of a generally toroidal structure, whose two ends extend one inside the other, creating a sealed-off volume inside the balloon, whereby the filling of the volume can be adjusted from outside and a draining lumen radially inside the inner layer of the balloon, the outer layer of the tube comprising a radially expanded intra-rectal device which is placed inside the rectum or the intestine of a patient during use, and comprising a trans-anal device which extends through the anus of the patient or his abdominal wall, and a stiffening sleeve element positioned inside the draining lumen of the device, keeping the lumen open and facilitating the uptake and passage of feces through the intra-rectal segment of the draining lumen.

BALLOON-EQUIPPED ENDOSCOPIC DEVICES AND METHODS THEREOF

An endoscopy system including a balloon-equipped endoscope including a balloon which is configured for slidable frictional engagement with an interior wall of a body passageway and axial stretching of the interior wall when inflated to a slidable frictional engagement pressure and displaced axially along the body passageway and a balloon inflation subsystem operative to selectably inflate the balloon to the slidable frictional engagement pressure.

APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS

An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including proximal and distal ends, a lumen extending there between, and a balloon on the distal end. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The valve may be biased to be closed, e.g., by a spring element disposed within the balloon. Optionally, the apparatus also includes an actuator for expanding a helical member within the balloon interior, e.g., either before or after expanding the balloon, such that the helical member and balloon may adopt an expanded helical shape for removing material within a body lumen. 1. An apparatus for treating a body lumen , comprising:an elongate outer member including a proximal end, a distal end sized for introduction into a body lumen, and a first lumen extending between the proximal end and an outlet in the distal end;an inner member slidably disposed within the first lumen and having a cross-section smaller than the first lumen such that an annular lumen is defined between the outer and inner members between the outer member proximal end and the outlet, the inner member comprising a proximal end adjacent the outer member proximal end, and a distal end adjacent the outer member distal end;an expandable balloon comprising a proximal end secured to the outer member distal end and a distal end secured to the outer member distal end distal to the proximal end, the balloon comprising an interior communicating with the first lumen via one or more openings in the outer member distal end;a sealing member on the inner member distal end, the inner member being movable between a first position wherein the sealing member is spaced from the outlet such ...

SUCTION CATHETER WITH DISTAL SUCTION MODULATION

A cleaning catheter includes tubular main body, shaped so as to define a distal-most suction orifice; and a suction lumen, a distal portion of which is in fluid communication with the distal-most suction orifice. An outer wall of the main body is shaped so as to define an opening extending through an outer wall into the suction lumen at an axial location proximal to the distal-most suction orifice. An inflatable element is mounted to the main body along the opening. A collapsible membrane is positioned along the opening within an interior of the inflatable element, so as to define an inflatable chamber between a wall of inflatable element and the collapsible membrane. The collapsible membrane is positioned to at least partially occlude the suction lumen upon at least partial inflation of the inflatable chamber. The collapsible membrane is slack when the inflatable chamber is not inflated. 182-. (canceled)83. Apparatus for use with a suction source , the apparatus comprising a cleaning catheter , which comprises:an elongate, flexible, tubular main body, which is shaped so as to define a distal-most suction orifice;a suction lumen arranged along the main body at least partially within the main body in intermittent fluid communication with the suction source, wherein a distal portion of the suction lumen is in fluid communication with the distal-most suction orifice, and wherein an outer wall of the main body is shaped so as to define an opening extending through the outer wall of the main body into the suction lumen at an axial location proximal to the distal-most suction orifice;an inflatable element, which is mounted to the main body at least partially along the opening; anda collapsible membrane, which is at least partially positioned along the opening within an interior of the inflatable element, so as to define an inflatable chamber between a wall of inflatable element and the collapsible membrane,wherein the collapsible membrane is positioned to at least ...

INTRAGASTRIC DEVICE WITH EXPANDABLE PORTIONS

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 1. An intragastric balloon configured to have a useful life in an in vivo gastric environment of at least 30 days , comprising:{'sub': 2', '2, 'sup': '2', 'a polymeric wall configured to have, under conditions of an in vivo gastric environment, a permeability to COof more than 10 cc/m/day, such that a rate and an amount of diffusion of COfrom the in vivo gastric environment into a lumen of the balloon through the polymeric wall is controlled, at least in part, by a concentration of an inert gas in an initial fill gas, wherein the polymeric wall comprises one or more expandable sections configured to stretch from 10% to 400% in response to an increased volume of a fluid inside the volume-occupying subcomponent; and'}a valve system configured for introducing the initial fill gas into the lumen of the balloon in the in vivo gastric environment.2. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a three layer CObarrier material consisting of nylon/polyvinylidene chloride/polyethylene.3. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a two layer CObarrier material consisting of nylon/polyethylene material and no additional CObarrier material.4. The intragastric balloon of claim 1 , wherein the initial fill gas consists essentially of SFand N.5. The intragastric balloon of claim 1 , wherein the initial fill gas consists essentially of SF.6. The intragastric balloon of claim 1 , wherein an entirety of the polymeric wall is expandable.7. The intragastric balloon of claim 1 , comprising one or more non-expandable sections.8. The intragastric balloon of claim 1 , wherein the one or more expandable sections comprises a band positioned around any section of the intragastric balloon.9. The intragastric balloon of claim 8 , wherein the ...

MULTI-BALLOON DILATION CATHETER

A method of dilating a target anatomical structure of an ear, a nose, or a throat of a patient includes inserting a distal end of a balloon catheter into the ear, the nose, or the throat. The balloon catheter includes a balloon assembly coaxially disposed along a proximally extending shaft. The balloon assembly includes at least first and second dilation balloons that at least partially overlap one another. The method also includes distally advancing the distal end until the balloon assembly is disposed in the target anatomical structure. The method also includes selectively dilating the target anatomical structure based on a diameter of the target anatomical structure by inflating the first dilation balloon to a first diameter or inflating the second dilation balloon to a second diameter that is greater than the first diameter. The second inflation lumen is not in fluid communication with the first inflation lumen. 1. A method of dilating a target anatomical structure of an ear , a nose , or a throat of a patient , the method comprising:(a) inserting a distal end of a balloon catheter into the ear, the nose, or the throat of the patient, wherein the balloon catheter includes a balloon assembly coaxially disposed along a proximally extending shaft, wherein the balloon assembly includes at least first and second dilation balloons that at least partially overlap one another;(b) distally advancing the distal end of the balloon catheter until the balloon assembly is disposed in the target anatomical structure of the ear, the nose, or the throat of the patient; and (i) inflating the first dilation balloon to a first diameter by communicating an inflation fluid through a first inflation lumen, or', '(ii) inflating the second dilation balloon to a second diameter that is greater than the first diameter by communicating the inflation fluid through a second inflation lumen, wherein the second inflation lumen is not in fluid communication with the first inflation lumen., '(c) ...

Inflation devices and systems for balloon catheters and methods for use

Inflation devices and methods for using them are provided for selectively inflating and deflating multiple balloons on a catheter. For example, the inflation device may include a first valve including a plurality of first valve ports and a first valve member movable between multiple positions for opening and closing fluid paths between the first valve ports, a second valve including a plurality of second valve ports and a second valve member movable between multiple positions for opening and closing fluid paths between the second valve ports, and an actuator coupled to the first and second valve members for directing the first and second valve members between multiple positions, e.g., to selectively pull vacuum and sequentially inflate the balloons.

BEATING HEART CONTROLLER AND SIMULATOR

Systems, devices and methods for a surgical training tool that drives movement of an organ In order to reproduce a movement of that organ to mimic the conditions of a live surgical procedure. 1. A method of preparing a training model by animating a heart of a cadaver , the method comprising:advancing a first catheter having a first expandable member into the cadaver;advancing a second catheter having a second expandable member into the cadaver:positioning the first expandable member into a first ventricle of the cadaver heart;positioning the second expandable member into a second ventricle of the cadaver heart;coupling the first catheter to a first fluid path, the first fluid path being in fluid communication with a positive pressure source:coupling the second catheter to a second fluid path, the second fluid path being in fluid communication with the positive pressure source that provides a fluid flow; andmonitoring a parameter of the fluid flow in the first catheter and the second catheter to control the fluid flow in the first fluid path and the second fluid path to pressurize and depressurize the first expandable member and the second expandable member respectively to produce a beating pattern in the cadaver heart.2. The method of claim 1 , wherein the first fluid path comprises a first valve claim 1 , and where the second fluid path comprises a second valve.3. The method of claim 1 , further comprising an adjustable valve claim 1 , where the first fluid path and second fluid path are fluidly isolated in the adjustable valve.4. The method of claim 1 , where the parameter of the fluid flow comprises a parameter selected from a group consisting of a time of flow claim 1 , a volume of flow claim 1 , a pressure claim 1 , and a combination thereof.5. The method of claim 1 , further comprising:advancing a third catheter having a third expandable member into the cadaver;positioning the third expandable member into a first atrium of the cadaver heart;coupling the third ...

SEGMENTED BALLOON CATHETER

A catheter has an inflatable assembly at its distal portion, including a containment chamber, an axial core and a plurality of longitudinally oriented partitions extending from the axial core to the wall of the chamber to divide the containment chamber into at least four inflatable sectors. Hydraulic valves are connected to respective sectors to enable selective inflation of the sectors by a fluid when the valves are connected to a source of the fluid, and at least one surface electrode is mounted on each of the sectors. When introduced into a heart chamber and diametrically opposed sectors are inflated the assembly is stably fixed against the walls of the heart chamber and readings can be obtained from the surface electrodes of the inflated sectors. 1. A medical apparatus , comprising:a catheter having an elongated shaft and a distal portion, the distal portion comprising an inflatable assembly,wherein the inflatable assembly comprises a containment chamber having an outer wall, an outer surface, an axial core and a plurality of longitudinally oriented partitions extending from the axial core to the outer wall to divide the containment chamber into at least four inflatable sectors, the sectors being externally delimited by respective bounding portions of the outer surface;hydraulic valves connected to respective sectors to enable selective inflation of the sectors by a fluid when the valves are connected to a source of the fluid; andat least one surface electrode mounted on each of the bounding portions.2. The apparatus according to claim 1 , further comprising a tip electrode disposed on the catheter distal to the inflatable assembly.3. The apparatus according to claim 1 , wherein the outer surface has perforations formed therethrough for egress of the fluid from the containment chamber.4. The apparatus according to claim 1 , further comprising a control processor operative to control the valves.5. The apparatus according to claim 1 , wherein the at least one ...

METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES

A method of reducing the risk of clinical sequelae to catheter induced vascular injuries may include introducing a guide wire into a vascular sheath residing in a blood vessel, proximally retracting the vascular sheath while leaving the wire in place, and observing indicia of the presence or absence of a vascular injury caused to the blood vessel by the vascular sheath or a procedural catheter previously advanced through the vascular sheath. If indicia of a vascular injury are observed, the method may further involve proximally retracting the guide wire to position the inflatable balloon adjacent the injury and inflating the balloon to reduce blood flow past the injury, while leaving the guide wire in place to provide subsequent access to the injury. The inflatable balloon can be inflated and deflated through a valve positioned at the proximal end of the guide wire. 1. A vascular guide wire , comprising: a proximal portion;', 'a flexible distal portion that is at least about 15 cm long and is more flexible than the proximal portion;', 'a transition portion between the proximal and distal portions;, 'an elongate tubular body having a proximal end, a distal end and a lumen extending longitudinally through at least part of the body, the elongate body comprising;'}an inflatable balloon secured to the elongate body and in communication with the lumen, the inflatable balloon spanning the transition portion;a sealing member having an inner diameter and an outer diameter positioned in the lumen of the elongate body at the proximal portion of the elongate body and configured to couple with an inflation device to allow for inflation and deflation of the balloon;a piston assembly without a lumen for insertion into the lumen of the elongate body at the proximal end, the piston assembly having a handle with an integral piston, the piston extending through the inner diameter of the sealing member when the sealing member is in a closed state and the piston retracted axially from ...

PRESSURE CONTROL SYSTEM FOR INTRAGASTRIC DEVICE

Devices and methods for treating obesity are provided. More particularly, intragastric devices and devices for inflating and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 1. A system inflating for performing an inflation procedure to inflate an inflatable intragastric device , the system comprising:a) an inflation fluid container comprising an inflation fluid;b) an inflatable intragastric balloon;c) a fluid pathway fluidly connecting the inflation fluid container and the balloon;d) at lease one valve disposed along the fluid pathway and configured to control a volume of gas flowing through the fluid pathway into the balloon;e) a pressure gauge positioned along the fluid pathway so as to measure a balloon pressure within the balloon; and i) provide instructions to the valve to dispense a volume of inflation fluid into the fluid pathway;', 'ii) provide instructions to the valve to block the flow of the inflation fluid into the fluid pathway;', 'iii) receive balloon pressure measurements from the pressure gauge;', 'iv) determine if the balloon is located within a constrained space, based upon the balloon pressure measurements., 'f) a computing device configured to2. The system of claim 1 , wherein the constrained space is a first constrained space and the computing device is further configured to determine if the balloon is located within a second constrained space claim 1 , based upon the balloon pressure measurements.3. The system of claim 2 , wherein the computing device is configured to distinguish between the first and second constrained spaces.4. The system of claim 1 , wherein the computing device is further configured toa) compare the balloon pressure measurement to a target balloon pressure; and i) instructions to vent inflation fluid from the balloon, when the balloon pressure measurement is above the target balloon pressure;', 'ii) instructions to continue the inflation procedure; and', 'iii) instructions to ...

INTRAGASTRIC DEVICE

An implant configured for ingestion by a patient. After the implant has been swallowed by the patient and is disposed within the target location, e.g. the patient's stomach, an inflation subcomponent causes the implant to expand from a compact delivery state to an expanded, volume-occupying, deployed state. In the deployed state the implant creates a sensation of satiety in the patient stomach and thereby aids in limiting food intake and obesity. After a predetermined time a deflation subcomponent is actuated and the implant reduces in size so as to allow it to pass through the remainder of the patient's digestive track. The device may further incorporate tracking and visualization subcomponents, as well as pharmaceutical delivery subcomponents. 1. (canceled)2. A swallowable , intragastric balloon system comprising:a balloon comprising a self-sealing valve system attached to a wall of the balloon in a central lumen of the balloon by an adhesive with a shear force greater than about 40 N, the self-sealing valve system comprising a septum, a retaining structure, and a continuous ring;an inner container within the central lumen of the balloon, the inner container containing from about 0.28 grams to about 4 grams of an inflation agent; andan outer container configured to be swallowed by a patient without assistance, the outer container comprising a material and a structure configured to control timing of inflation, and containing the inner container and the balloon in a compacted state.3. The system of claim 2 , wherein the septum has a durometer that is less than a durometer of the retaining structure.4. The system of claim 2 , wherein the continuous ring is configured to exert a compressive force on the septum.5. The system of claim 2 , wherein the balloon has a weight of less than about 15 g.6. The system of claim 2 , wherein the balloon is configured to have a shape upon full inflation selected from the group consisting of ellipsoid claim 2 , spheroid claim 2 , and ...

Reinforced Balloon Catheter

A balloon catheter is described, having a reinforced, co-axial, duel lumen design. At least one of the lumens is formed of a multilayer, tubular element in which one of the layers functions, in part, to provide radial reinforcement to the tubular element.

Balloon Catheter System

A balloon catheter system enabling balloon stretching and deflating, and balloon stretch-releasing and inflating operations to be performed at a time with a single operation. The system includes a catheter shaft including outer and inner tubes slidable to each other and a deflatable/inflatable balloon arranged between the distal ends thereof. A solution transport path is formed between the outer and inner tubes. Anterior and posterior tanks are arranged in a handle. The tanks and the inner tube passing through the central portion thereof are slidable to each other. Stopcocks are mounted in sliding portions between the inner tube and these tanks. These tanks are connected to the inside of the balloon via the solution transport path. A piston is provided inside the posterior tank. Thus, the inner pressures of these tanks change by reciprocating the inner tube fixed to the piston, thus simplifying balloon deflating and inflating operations. 1. A balloon catheter system comprising:a catheter shaft including an outer tube and an inner tube, said outer and inner tubes being slidable to each other;an inflatable and deflatable balloon arranged between a distal end of said outer tube and a vicinity of a distal end of said inner tube;a solution transport path formed between said outer tube and said inner tube, in communication with an inside of said balloon;two, respectively anterior and posterior tanks arranged in a handle of a catheter, in communication with each other via a connecting pipe, said anterior and posterior tanks being slidable relative to said inner tube passing through central portions thereof;leakproof packing members arranged on sliding portions between said inner tube and said anterior and posterior tanks, said anterior and posterior tanks being allowed to communicate with an inside of said balloon via said solution transport path; anda piston provided inside a front section of said posterior tank to allow inner pressures of said tanks to be changed by a ...

SYSTEMS AND METHODS FOR SELECTIVELY OCCLUDING THE SUPERIOR VENA CAVA FOR TREATING HEART CONDITIONS

Systems and methods and devices are provided for treating conditions such as heart failure and/or pulmonary hypertension by at least partially occluding flow through the superior vena cava for an interval spanning multiple cardiac cycles. A catheter with an occlusion device is provided along with a controller that actuates a drive mechanism to provide at least partial occlusion of the patients superior vena cava, which reduces cardiac filling pressures, and induces a favorable shift in the patients Frank-Starling curve towards healthy heart functionality and improved cardiac performance. The occlusion device may include a lumen obstructed by a relief valve that may permit fluid flow through the occlusion device to release an excessive build-up of pressure. 1. (canceled)2. The system of claim 28 , further comprising:a first pressure sensor disposed on the catheter proximal to the flow limiting element, the first pressure sensor outputting a first pressure signal; anda second pressure sensor disposed on the catheter and distal to the flow limiting element, the second pressure sensor outputting a second pressure signal,wherein the controller is configured to generate a first signal corresponding to a difference between the first pressure signal and the second pressure signal, the first signal indicative of a degree of occlusion of the flow limiting element.3. The system of claim 28 , further comprising an azygos vein occlusion balloon disposed on the catheter proximal to the flow limiting element claim 28 , wherein the flow limiting element is an SVC occlusion balloon.4. The system of claim 3 , wherein the azygos vein occlusion balloon is configured to be selectively actuated to at least partially occlude an azygos vein of the patient.5. The system of claim 4 , wherein the azygos vein occlusion balloon and the SVC occlusion balloon are independently actuated.6. The system of claim 2 , wherein the second pressure sensor is positioned between an azygos vein occlusion ...

THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. 1. (canceled)2. A therapeutic preparation comprising a exenatide , the preparation shaped as a solid tissue penetrating member having a pointed end , the preparation configured to be contained in a swallowable enclosure having a tubular shape with curved ends and to be released from the enclosure to penetrate and be inserted into a gastro-intestinal (GI) wall of a patient after oral ingestion of the enclosure by the application of force upon the preparation , wherein upon insertion into the GI wall , the preparation releases exenatide into the blood stream of the patient.3. The preparation of claim 2 , wherein the preparation is adapted for insertion into a wall of the patient's small intestine.4. The preparation of claim 2 , wherein the preparation is adapted for insertion into a wall of the patient's stomach.5. The preparation of claim 2 , wherein the preparation is adapted to be operably coupled to a delivery means having a first configuration and a second configuration claim 2 , ...

Handle Component for Providing a Pressurized Material

A handle component of a medical device is disclosed for delivering a material to an enclosed cavity or space. The handle component includes a self-contained mechanism for holding the material and for providing or releasing the material to the enclosed cavity. The handle component also includes a pressure relief valve in fluid communication with the mechanism and the enclosed cavity. The pressure relief valve is configured to indicate when delivery of the material to the enclosed cavity reaches a preselected or set pressure and to thereby assure precise filling of the enclosed cavity with the material. 1. A handle component of a medical device for delivering a material to an enclosed cavity comprising:a self-contained mechanism for holding the material and for providing the material to an enclosed cavity; anda pressure relief valve in fluid communication with the mechanism and the enclosed cavity, the pressure relief valve being configured to indicate when delivery of the material to the enclosed cavity reaches a preselected pressure.2. The handle component of claim 1 , wherein the medical device is a balloon catheter claim 1 , the material is an inflation fluid and the enclosed cavity is a balloon of the balloon catheter.3. The handle component of claim 2 , wherein the mechanism is in fluid communication with a lumen of the balloon catheter claim 2 , and wherein the lumen is in fluid communication with the balloon.4. The handle component of claim 3 , wherein the mechanism comprises a syringe that contains the inflation fluid for inflating the balloon to the preselected pressure when a plunger of the syringe is depressed.5. The handle component of claim 4 , wherein the preselected pressure is between 0.1 ATM and 20 ATM.6. The handle component of claim 5 , wherein the mechanism further comprises an actuation cap that is coupled to a head of the plunger of the syringe and that is threadably engaged with the handle component when the mechanism is in a locked ...

INFLATABLE BALLOON STENT

An illustrative stent may comprise an elongated tubular balloon having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular balloon may have an inner wall and an outer wall, the inner wall and the outer wall connected at the first end and the second end to define an enclosed inflation chamber between the inner wall and the outer wall. The stent may further include an inflation valve. 1. A stent , the stent comprising:an elongated tubular balloon having a first end and a second end and an intermediate region disposed therebetween, the elongated tubular balloon having an inner wall and an outer wall, the inner wall and the outer wall connected at the first end and the second end to define an enclosed inflation chamber between the inner wall and the outer wall; andan inflation valve.2. The stent of claim 1 , wherein an inner surface of the inner wall of the elongated tubular balloon defines a lumen extending from the first end to the second end.3. The stent of claim 1 , wherein the inflation valve is disposed adjacent to one of the first or second ends of the elongated tubular balloon.4. The stent of claim 1 , wherein the inflation valve is disposed adjacent to the intermediate region of the elongated tubular balloon.5. The stent of claim 1 , wherein the first end has an outer diameter larger than an outer diameter of the intermediate region and the second end has an outer diameter larger than an outer diameter of the intermediate region.6. The stent of claim 1 , wherein the inflation valve comprises a one-way valve.7. The stent of claim 1 , wherein the inflation valve comprises a break away valve.8. The stent of wherein an outer surface of the outer wall comprises a textured surface.9. The stent of claim 8 , wherein the textured surface includes raised projections.10. The stent of claim 16 , wherein the elongated tubular balloon comprises polyethylene terephthalate.11. The stent of claim 16 , further comprising at least ...

FLOW REGULATION VALVE FOR CONTROLLING INFLATION RATE OF A BALLOON DEPLOYING A SCAFFOLD

An apparatus and method for controlling inflation pressure, pressurization rate, and volumetric flow rate of a balloon during deployment of a stent or scaffold is disclosed. 1. A flow regulator for regulating flow of an inflation fluid to a balloon catheter , comprising:a valve body enclosing a control chamber comprising a passageway for fluid flow;a distal end of the valve body with a distal flow orifice for connection with the balloon catheter,a proximal end of the valve body with a proximal flow orifice for connection with a catheter in fluid communication an inflation device,a slidable restrictor body positioned within the control chamber to allow fluid flow distally or proximally through the restrictor body;a valve seat positioned distal to the restrictor body comprising a valve seat orifice which allows fluid to flow out of the distal flow orifice,wherein the slidable restrictor body is operable to slide distally in response to fluid flow in the distal direction toward the valve seat during inflation of the balloon, wherein as a distal end of the restrictor body approaches the valve seat they cooperate to increase restriction to fluid flow which controls the pressurization rate of the balloon to within a specified range.2. The flow regulator of claim 1 , further comprising a biasing element that applies a biasing force that opposes the distal sliding of the restrictor body.3. The flow regulator of claim 1 , wherein the restrictor body comprises a conduit positioned within the control chamber to allow fluid flow along its axis.4. The flow regulator of claim 3 , wherein a distal end of the conduit comprises a piston with an opening to allow fluid flow distally or proximally.5. The flow regulator of claim 3 , wherein a proximal end of the conduit is open to allow unrestricted flow distally or proximally.6. The flow regulator of claim 1 , wherein a distal end of the restrictor body comprises wall with at least one opening to allow fluid flow distally or proximally ...

BALLOON CATHETER

A balloon catheter having an elongated catheter shaft defining a fluid drainage lumen and a balloon inflation lumen. The balloon catheter includes a fluid drainage port disposed about the distal end of the catheter shaft in fluid communication with the fluid drainage lumen, and a balloon inflation port disposed about the distal end of the catheter shaft in fluid communication with the balloon inflation lumen. A balloon portion is disposed about the distal end of the catheter shaft in fluid communication with the balloon inflation port. A release device is disposed in fluid communication with the balloon portion and the fluid drainage lumen, and includes an activating member. A tether is attached to the activating member of the release device. Tension applied to the tether activates the release device, enabling fluid flow from the balloon portion into the fluid drainage lumen and out of the body. 1. A balloon catheter comprising: an elongated catheter shaft defining a fluid drainage lumen and a balloon inflation lumen , the catheter shaft having a proximal end and a distal end; a fluid drainage port disposed about the distal end of the catheter shaft , the fluid drainage port in fluid communication with the fluid drainage lumen; a balloon inflation port disposed about the distal end of the catheter shaft , the balloon inflation port in fluid communication with the balloon inflation lumen; a balloon portion disposed about the distal end of the catheter shaft , the balloon portion in fluid communication with the balloon inflation port; a release device in fluid communication with the balloon portion and the fluid drainage lumen , the release device comprising an activating member; and a tether having a proximal end and a distal end , the distal end of the tether attached to the activating member of the release device.2. A balloon catheter according to claim 1 , wherein the release device further comprises a pressure release port in fluid communication with the fluid ...

Stretch Valve Balloon Catheter and Methods for Producing and Using Same

A safety balloon catheter includes a catheter having a stretch valve, a connector, a balloon inflated with an inflation fluid, a hollow inflation lumen extending through the catheter to the balloon and conveying inflation fluid thereto and therefrom, a hollow second lumen, and a balloon drainage port fluidically connecting the balloon to the second lumen. The stretch valve has a hollow base fixed in the second lumen at a proximal catheter end and shaped to permit a fluid therethrough and a hollow plug slidably positioned in the second lumen at a given distance from the base to, in a steady state, prevent inflation fluid from passing through the drainage port and, when actuated, slide within the second lumen to permit inflation fluid to pass through the drainage port and into the second lumen. The connector connects the base and the plug and has a length greater than the given distance. 1 a drain lumen extending through the shaft and shaped to drain fluid adjacent the distal tip proximally through the drain lumen and out the drain end;', 'a distal hollow balloon portion defining a balloon interior and having at least one inflation port fluidically connected to the balloon interior, the balloon portion inflating outwardly to a diameter greater than the outer diameter of the shaft when inflated with inflation fluid;', 'at least one inflation lumen parallel to the drain lumen and fluidically connected to the balloon interior through the at least one inflation port, the at least one inflation lumen shaped to inflate the balloon interior with the inflation fluid; and', 'a balloon drainage port fluidically connecting the balloon interior to the drain lumen; and, 'a flexible, multi-lumen shaft having an outer diameter, a distal tip, and a proximal catheter end with a drain end, the multi-lumen shaft defining a body removably disposed in the balloon drainage port and shaped to prevent fluid from passing through the balloon drainage port when disposed in the balloon drainage ...

MEDICAL APPARATUSES AND RELATED METHODS FOR INTRANASAL FLUID DELIVERY

A method includes blocking a posterior opening of a nasal cavity of a patient and delivering a medical fluid through a catheter to a sphenopalatine ganglion of the patient after blocking the posterior opening of the nasal cavity. 1. A medical apparatus comprising:a catheter body having a medical fluid lumen, the catheter body comprising an insertion end region configured to be inserted into a nasal cavity of a patient, a lateral portion of the insertion end region of the catheter body defining a side opening in fluid communication with the medical fluid lumen of the catheter body; andan expandable member secured to a portion of the catheter body distal to the side opening, the expandable member being configured to block a posterior opening of the nasal cavity of the patient when the insertion end region of the catheter body is positioned within the nasal cavity of the patient and the expandable member is expanded,wherein the medical fluid lumen is configured to be placed in fluid communication with a source of the medical fluid such that the medical fluid can be passed through the medical fluid lumen and exit the side opening to contact a sphenopalatine ganglion of the patient when the side opening is positioned within the nasal cavity of the patient.2. The apparatus of claim 1 , further comprising a stabilizing member securable to the catheter body and sized and dimensioned to inhibit the stabilizing member from entering the nasal cavity of the patient through an anterior opening of the nasal cavity of the patient claim 1 , the stabilizing member being positionable against a nose of the patient.3. The apparatus of claim 2 , wherein the stabilizing member is slidable along the catheter body.4. The apparatus of claim 2 , wherein:the stabilizing member is lockable in a position along the catheter body such that, when the expandable member blocks the posterior opening and the stabilizing member is positioned against the nose of the patient and locked, the stabilizing ...

Uterine Manipulator

A uterine manipulator device includes: an elongated cannulated tube comprising a proximal end and a distal end; a cervical cup having a top proximal portion of a first diameter and a base distal portion of a second smaller diameter, wherein: the base distal portion includes a hole formed therein having a perimeter including a distal end and a proximal end, and including a longitudinal axis positioned therethrough; one of the proximal end of the perimeter and the distal end of the perimeter is angled away from the longitudinal axis and the other of the proximal end of the perimeter and the distal end of the perimeter is in line with the longitudinal axis; and the elongated cannulated tube is positioned through the hole in the cervical cup. 1. A uterine manipulator device comprising:an elongated cannulated tube comprising a proximal end and a distal end; the base distal portion includes a hole formed therein having a perimeter including a distal end and a proximal end, and including a longitudinal axis positioned therethrough;', 'one of the proximal end of the perimeter and the distal end of the perimeter is angled away from the longitudinal axis and the other of the proximal end of the perimeter and the distal end of the perimeter is in line with the longitudinal axis; and', 'the elongated cannulated tube is positioned through the hole in the cervical cup., 'a cervical cup having a top proximal portion of a first diameter and a base distal portion of a second smaller diameter, wherein2. The device of claim 1 , wherein the proximal end of the elongated cannulated tube is nonlinear.3. The device of claim 1 , further comprising a vaginal cup positioned distally from the cervical cup on the elongated cannulated tube claim 1 , wherein the vaginal cup includes a top distal portion with a first diameter and a base proximal portion with a second smaller diameter claim 1 , and wherein the vaginal cup is configured to maintain pneumoperitoneum during use.4. The device of claim ...

PRESSURE CONTROL SYSTEM FOR INTRAGASTRIC DEVICE

Devices and methods for treating obesity are provided. More particularly, intragastric devices and devices for inflating and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 1. A system inflating for performing an inflation procedure to inflate an inflatable intragastric device , the system comprising:a) an inflation fluid container comprising an inflation fluid;b) an inflatable intragastric balloon;c) a fluid pathway fluidly connecting the inflation fluid container and the balloon;d) at lease one valve disposed along the fluid pathway and configured to control a volume of gas flowing through the fluid pathway into the balloon;e) a pressure gauge positioned along the fluid pathway so as to measure a balloon pressure within the balloon; and i) provide instructions to the valve to dispense a volume of inflation fluid into the fluid pathway;', 'ii) provide instructions to the valve to block the flow of the inflation fluid into the fluid pathway;', 'iii) receive balloon pressure measurements from the pressure gauge;', 'iv) determine if the balloon is located within a constrained space, based upon the balloon pressure measurements., 'f) a computing device configured to2. The system of claim 1 , wherein the constrained space is a first constrained space and the computing device is further configured to determine if the balloon is located within a second constrained space claim 1 , based upon the balloon pressure measurements.3. The system of claim 2 , wherein the computing device is configured to distinguish between the first and second constrained spaces.4. The system of claim 1 , wherein the computing device is further configured toa) compare the balloon pressure measurement to a target balloon pressure; and i) instructions to vent inflation fluid from the balloon, when the balloon pressure measurement is above the target balloon pressure;', 'ii) instructions to continue the inflation procedure; and', 'iii) instructions to ...

INTRAGASTRIC DEVICE WITH EXPANDABLE PORTIONS

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 1. An intragastric balloon configured to have a useful life in an in vivo gastric environment of at least 30 days , comprising:{'sub': 2', '2, 'sup': '2', 'a polymeric wall configured to have, under conditions of an in vivo gastric environment, a permeability to COof more than 10 cc/m/day, such that a rate and an amount of diffusion of COfrom the in vivo gastric environment into a lumen of the balloon through the polymeric wall is controlled, at least in part, by a concentration of an inert gas in an initial fill gas, wherein the polymeric wall comprises one or more expandable sections configured to stretch from 10% to 400% in response to an increased volume of a fluid inside the volume-occupying subcomponent; and'}a valve system configured for introducing the initial fill gas into the lumen of the balloon in the in vivo gastric environment.2. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a three layer CObarrier material consisting of nylon/polyvinylidene chloride/polyethylene.3. The intragastric balloon of claim 1 , wherein the polymeric wall comprises a two layer CObarrier material consisting of nylon/polyethylene material and no additional CObarrier material.4. The intragastric balloon of claim 1 , wherein the initial fill gas consists essentially of SFand N.5. The intragastric balloon of claim 1 , wherein the initial fill gas consists essentially of SF.6. The intragastric balloon of claim 1 , wherein an entirety of the polymeric wall is expandable.7. The intragastric balloon of claim 1 , comprising one or more non-expandable sections.8. The intragastric balloon of claim 1 , wherein the one or more expandable sections comprises a band positioned around any section of the intragastric balloon.9. The intragastric balloon of claim 8 , wherein the ...

APPARATUS FOR PREVENTING OVER INFLATION OF THE RETENTION BALLOON IN MEDICAL CATHETERS AND AIRWAY DEVICES

The body has a fluid inlet port for receiving pressurized fluid and a fluid outlet port connected to the retention balloon. A first passage connects the fluid inlet port and the fluid outlet port. A second passage in the body is connected to the balloon fluid return path and is at the pressure of the retention balloon. A valve prevents fluid flow through the first passage when actuated. The valve includes a pressure-responsive member movable to a position to obstruct fluid flow in response to fluid pressure in the second passage exceeding the predetermined level. Flexible means such as a membrane defines a normally open portion of the first fluid passage, which is closed by the moveable means bearing on the membrane when pressure exceeding the predetermined level actuates the valve. 1. Apparatus for limiting fluid pressure in the medical catheter retention balloon designed for use with a source of pressurized having a connector associated therewith , wherein the catheter has a supply fluid path from the apparatus for filling the balloon and a return fluid path communicating with the balloon connected to the apparatus , the apparatus comprising: a body with a fluid inlet port for receiving the connector associated with the pressurized fluid source and a fluid outlet port; a first passage connecting said fluid inlet port and the fluid outlet port of said body; a second passage connected to said return fluid path; and means for preventing fluid flow through said first passage when the fluid pressure in said second passage exceeds a predetermined level.2. The apparatus of wherein said fluid flow preventing means comprises means for moveable said second passage into a first portion connected to said return fluid path and a second portion claim 1 , said moveable means being movable between a first position claim 1 , wherein fluid flow through said first passage is not obstructed claim 1 , and a second position wherein fluid flow through said first passage is obstructed ...

PORTABLE MEDICAL GAS DELIVERY SYSTEM

An apparatus for producing gas for use in medical applications. The apparatus includes a compressed gas unit having at least one container of compressed gas and a solenoid valve. An adjustable pressure regulator communicably connected to the gas container, separate and distinct from the solenoid valve, is adjusted to control the pressure of the gas provided from the container to tire solenoid valve An electrical power source Is connected to the solenoid valve. A pressure activated electronic switch connected to the power source is responsive to a selected amount of voluntary fingertip, pressure for opening the solenoid valve to transmit the gas therethrough to a conduit, which further transmits the gas to a destination for use or storage. 116-. (canceled)17. An apparatus for dispensing medical grade gas , said apparatus comprising: a housing including a cylinder cartridge puncture valve adapted for attachment to a source of compressed gas,', 'a solenoid communicably connected to the source of compressed gas, the solenoid including an inlet and an outlet,', 'a pressure adjustable gas regulator separate and distinct from the solenoid and communicably interconnected between the source of compressed gas and the inlet of the solenoid for selectively adjusting the pressure of the gas provided from the source of compressed gas to the solenoid, the gas regulator including a regulator adjustment knob to provide a selected level of pressure,', 'a pressure gauge connected between the gas regulator and the solenoid, and', 'a pressure activated electric switch engaged to selectively open the solenoid; and, 'a portable compressed gas unit includinga conduit communicably attached to the outlet of the solenoid for transmitting gas to a destination for storage or use in a medical application when the solenoid is opened by operation of the pressure activated electric switch.18. The apparatus of wherein the compressed gas includes at least one of carbon dioxide claim 17 , atmospheric ...

Cerebrospinal Fluid Flow Diverter

A device that can be placed within or near the cranial vault that fluctuates in size in response to changes in CSF pressure is disclosed. The device diminishes in size when CSF pressures rise and increases in size as CSF pressures diminish. The device has the effect of reducing the flow of CSF occurring in the foramen magnum and provides an alternative to craniovertebral decompression in Chiari I patients. The device may have applications in other neurologic illnesses associated with abnormal CSF flow, such as Idiopathic Syringomyelia, Normal Pressure Hydrocephalus, and CSF dural leaks. 120-. (canceled)21. A device comprising:a component having a variable component volume and capable of being installed either adjacent to or into a fluid space within a human cranial vault, the human cranial vault having an intracranial pressure;wherein the component comprises a flexible material that changes the component volume based on fluctuations in the intracranial pressure;wherein the component volume decreases when the intracranial pressure increases, thereby adding to the capacity of the human cranial vault and reducing additional increases of intracranial pressure; andwherein the component volume increases when the intracranial pressure decreases, thereby decreasing the capacity of the human cranial vault and reducing additional decreases of intracranial pressure.22. The device as in claim 21 , further comprising a measuring system for measuring changes in the intracranial pressure and for measuring changes in the component volume.23. The device as in claim 21 , wherein the fluid space within the intracranial vault is an intracranial subarachnoid space.24. The device as in claim 21 , wherein the fluid space within the intracranial vault is within the cerebral ventricles.25. The device as in claim 21 , wherein the component is implanted into the osseous cranial vault.26. The device as in claim 21 , wherein the component is a balloon.27. The device as in claim 21 , wherein the ...

BALLOON-EQUIPPED ENDOSCOPIC DEVICES AND METHODS THEREOF

An endoscopy system including a balloon-equipped endoscope including a balloon which is configured for slidable frictional engagement with an interior wall of a body passageway and axial stretching of the interior wall when inflated to a slidable frictional engagement pressure and displaced axially along the body passageway and a balloon inflation subsystem operative to selectably inflate the balloon to the slidable frictional engagement pressure. 1153-. (canceled)154. A method for performing a colonoscopy , comprising:advancing an endoscope through a colon, the endoscope comprising a viewing portion positioned at a distal end and a flexible polymeric unfolder mounted at the distal end of the endoscope, the flexible polymeric unfolder mounted proximal to the viewing portion and configured for generally circumferential slidable frictional engagement with an interior wall of the colon, wherein the flexible polymeric unfolder extends radially outward from the endoscope; andretracting the endoscope through the colon such that during retraction of the endoscope through the colon, natural folds within the colon are unfolded by engagement of the flexible polymeric unfolder with the interior wall of the colon such that features of interest within the colon become visible to the viewing portion.155. The method of claim 154 , wherein the polymeric unfolder is configured such that the polymeric unfolder is not visible to the viewing portion during retraction of the endoscope.156. The method of claim 154 , wherein during retraction of the endoscope claim 154 , the flexible polymeric unfolder is configured to enable systematic visual inspection of the colon.157. The method of claim 154 , wherein the flexible polymeric unfolder comprises a balloon.158. The method of claim 157 , wherein the balloon is configured to inflate to a slidable frictional engagement pressure.159. The method of claim 158 , wherein the slidable frictional engagement pressure is not higher than 35 millibar. ...

DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. 1. A drug-coated balloon catheter comprising:an elongated balloon having a nominal diameter of 4 mm to 50 mm and a length of 20 mm to 160 mm; and an initial drug load of a therapeutic agent, the therapeutic agent comprising paclitaxel, a paclitaxel analogue, docetaxel, a docetaxel analogue, taxol, a taxol analogue, rapamycin, a rapamycin analogue, sirolimus, a sirolimus analogue, everolimus, an everolimus analogue, tacrolimus, a tacrolimus analogue, mammalian target of rapamycin (mTOR) inhibitors, an mTOR inhibitor analogue, or a combination thereof, and', 'one or more additives, wherein a ratio of the therapeutic agent to the one or more additives in the coating layer is 0.1 to 10;, 'a coating layer overlaying an exterior surface of the balloon, the coating layer comprising'}wherein flushing a target site in a body lumen and holding the drug-coated balloon catheter in position at the target site to hydrate the coating layer is sufficient for the coating layer to release more than 30 wt % of the initial drug load of the therapeutic agent from the coating layer to the target site in the body lumen.2. The drug-coated balloon catheter of claim 1 , wherein the flushing comprises flushing the target site with a flushing media comprising water claim 1 , saline solution claim 1 , or a water solution comprising at least one water-soluble additive.3. The drug-coated balloon catheter of claim 1 , wherein holding the drug-coated balloon catheter at the target site comprises ...

Stretch Valve Balloon Catheter and Methods for Producing and Using Same

A safety balloon catheter includes a flexible, multi-lumen balloon catheter and a hollow barbell-shaped stretch valve. The balloon catheter has a proximal catheter end, a balloon defining a balloon interior to be inflated with an inflation fluid, a hollow inflation lumen extending through the catheter to the balloon interior and shaped to convey the inflation fluid to and from the balloon interior, and a hollow second lumen parallel to the inflation lumen; and a balloon drainage port fluidically connecting the balloon interior to the second lumen. The stretch valve is shaped to permit a fluid to pass therethrough and positioned in the second lumen to at least partially slide therein such that, in a steady state, a distal barbell end of the stretch valve prevents the inflation fluid from passing through the drainage port and, in an actuated state, the distal barbell end slides within the second lumen to permit the inflation fluid to pass through the drainage port and into the second lumen. 1. A safety balloon catheter , comprising: a proximal catheter end;', 'a balloon defining a balloon interior to be inflated with an inflation fluid;', 'a hollow inflation lumen extending through the catheter to the balloon interior and shaped to convey the inflation fluid to and from the balloon interior;', 'a hollow second lumen parallel to the inflation lumen; and', 'a balloon drainage port fluidically connecting the balloon interior to the second lumen; and, 'a flexible, multi-lumen balloon catheter having shaped to permit a fluid to pass therethrough; and', in a steady state, a distal barbell end of the stretch valve prevents the inflation fluid from passing through the drainage port; and', 'in an actuated state, the distal barbell end slides within the second lumen to permit the inflation fluid to pass through the drainage port and into the second lumen., 'positioned in the second lumen to at least partially slide therein such that], 'a hollow barbell-shaped stretch valve2. ...

INTRAGASTRIC DEVICE

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 120-. (canceled)21. An intragastric balloon system comprising: i) a polymeric wall with an inner surface defining a balloon lumen;', [ ["(a) an outer cylinder with a first end facing the w polymeric wall's inner surface and a second end facing the balloon lumen; and", "(b) an inner cylinder concentrically disposed within the outer cylinder and having a third end facing the polymeric wall's inner surface, and a fourth end facing the balloon lumen, the third end including an inward radial lip;"], '(1) a tube septum comprising, "(2) a self-sealing septum housed within the inner cylinder and compressed against the inner cylinder's inward radial lip; and", '(3) a polymeric material disposed concentrically between the inner cylinder and the outer cylinder;, "ii) a self-sealing valve system attached to the polymeric wall's inner surface, the valve system comprising:"}], 'a) an intragastric balloon comprising i) an outer container wall formed of a material that is erodible in an in vivo gastric environment;', 'ii) an outer container interior; and', 'iii) an opening in the outer container wall, the opening in the outer container wall providing fluid communication between the outer container interior and the in vivo gastric environment; wherein', 'iv) the outer container is sized and shaped so as to be swallowable by normal peristaltic motion;, 'b) an outer container releasably containing the intragastric balloon in a folded and compacted state, the outer container comprising i) catheter tubing with an open proximal end and and open distal end joined by a catheter lumen;', ["(1) a needle sleeve extending through the opening in the outer container wall and reversibly engaged with the valve system, wherein the valve system's polymeric material provides compressive forces against the ...

THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE

Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Many embodiments provide a swallowable device for delivering the agents. Particular embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. Embodiments also provide various drug preparations that are configured to be contained within the capsule, advanced from the capsule into the intestinal wall and degrade to release the drug into the bloodstream to produce a therapeutic effect. The preparation can be operably coupled to delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the intestinal wall. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. 1. A therapeutic preparation comprising exenatide, the preparation adapted for insertion into an intestinal wall after oral ingestion, wherein upon insertion, the preparation releases exenatide into the blood stream from the intestinal wall to achieve a Cin a shorter time period than a time period to achieve a Cfor an extravascularly injected dose of exenatide. This application is a continuation of U.S. patent application Ser. No. 15/339,722 (Attorney Docket No. 45126-709.302), filed Oct. 31, 2016, now U.S. patent Ser. No. ______, which is a continuation of U.S. patent application Ser. No. 14/620,827 (Attorney Docket No. 45126-709.301, now U.S. Pat. No. 9,511,121), filed Feb. 12, 2015, which is a continuation of U.S. patent application Ser. No. 13/538,748 (Attorney Docket No. 45126-709.201, now U.S. Pat. No. 8,969,293), filed Jun. 29, 2012, which claims the benefit of priority of Provisional Application No. 61/571,634, (Attorney Docket No. 45126-709.101), filed Jun. 29, 2011; and U.S ...

INTRAGASTRIC DEVICE

Devices and methods for treating obesity are provided. More particularly, intragastric devices and methods of fabricating, deploying, inflating, monitoring, and retrieving the same are provided. 120-. (canceled)21. An intragastric balloon system comprising: i) a polymeric wall with an inner surface defining a balloon lumen;', [ ["(a) an outer cylinder with a first end facing the w polymeric wall's inner surface and a second end facing the balloon lumen; and", "(b) an inner cylinder concentrically disposed within the outer cylinder and having a third end facing the polymeric wall's inner surface, and a fourth end facing the balloon lumen, the third end including an inward radial lip;"], '(1) a tube septum comprising, "(2) a self-sealing septum housed within the inner cylinder and compressed against the inner cylinder's inward radial lip; and", '(3) a polymeric material disposed concentrically between the inner cylinder and the outer cylinder;, "ii) a self-sealing valve system attached to the polymeric wall's inner surface, the valve system comprising:"}], 'a) an intragastric balloon comprising i) an outer container wall formed of a material that is erodible in an in vivo gastric environment;', 'ii) an outer container interior; and', 'iii) an opening in the outer container wall, the opening in the outer container wall providing fluid communication between the outer container interior and the in vivo gastric environment; wherein', 'iv) the outer container is sized and shaped so as to be swallowable by normal peristaltic motion;, 'b) an outer container releasably containing the intragastric balloon in a folded and compacted state, the outer container comprising i) catheter tubing with an open proximal end and open distal end joined by a catheter lumen;', ["(1) a needle sleeve extending through the opening in the outer container wall and reversibly engaged with the valve system, wherein the valve system's polymeric material provides compressive forces against the needle ...

APPARATUS AND METHODS FOR TREATING OBSTRUCTIONS WITHIN BODY LUMENS

An apparatus is provided that is operable in different modes to perform various functions for treating a body lumen. The apparatus includes a shaft including proximal and distal ends, a lumen extending there between, and a balloon on the distal end. The apparatus includes a valve on the distal end that selectively opens or closes an outlet communicating with the lumen. With the valve open, fluid introduced into the lumen exits the outlet into a body lumen. With the valve closed, fluid introduced into the lumen expands the balloon. The valve may be biased to be closed, e.g., by a spring element disposed within the balloon. Optionally, the apparatus also includes an actuator for expanding a helical member within the balloon interior, e.g., either before or after expanding the balloon, such that the helical member and balloon may adopt an expanded helical shape for removing material within a body lumen. 1. An apparatus for treating a body lumen , comprising:an outer member including a proximal end, a distal end sized for introduction into a body lumen, and a first lumen extending between the proximal and distal ends;an expandable balloon comprising a proximal end secured to the outer member distal end, and a distal end comprising an outlet, the balloon comprising an interior communicating with the first lumen and the balloon outlet;an inner member slidably disposed within the first lumen, the inner member comprising a proximal end adjacent the outer member proximal end, and a distal end extending from the balloon outlet;a sealing member on the inner member distal end, the inner member being movable between a first position wherein the sealing member is spaced from the balloon outlet such that fluid introduced through the first lumen passes through the balloon interior and out the balloon outlet, and a second position wherein the sealing member substantially seals the balloon outlet such that fluid introduced through the first lumen enters the balloon interior to expand ...

METHOD AND DEVICES FOR FLOW OCCLUSION DURING DEVICE EXCHANGES

A method of reducing the risk of clinical sequelae to catheter induced vascular injuries may include introducing a guide wire into a vascular sheath residing in a blood vessel, proximally retracting the vascular sheath while leaving the wire in place, and observing indicia of the presence or absence of a vascular injury caused to the blood vessel by the vascular sheath or a procedural catheter previously advanced through the vascular sheath. If indicia of a vascular injury are observed, the method may further involve proximally retracting the guide wire to position the inflatable balloon adjacent the injury and inflating the balloon to reduce blood flow past the injury, while leaving the guide wire in place to provide subsequent access to the injury. The inflatable balloon can be inflated and deflated through a valve positioned at the proximal end of the guide wire. 1. A vascular guide wire , comprising: a proximal portion;', 'a flexible distal portion that is at least about 15 cm long and is more flexible than the proximal portion;', 'a transition portion between the proximal and distal portions;, 'an elongate tubular body having a proximal end, a distal end and a lumen extending longitudinally through at least part of the body, the elongate body comprising;'}an inflatable balloon secured to the elongate body and in communication with the lumen, the inflatable balloon spanning the transition portion;a sealing member having an inner diameter and an outer diameter positioned in the lumen of the elongate body at the proximal portion of the elongate body and configured to couple with an inflation device to allow for inflation and deflation of the balloon;a piston assembly without a lumen for insertion into the lumen of the elongate body at the proximal end, the piston assembly having a handle with an integral piston, the piston extending through the inner diameter of the sealing member when the sealing member is in a closed state and the piston retracted axially from ...

BALLOON CATHETER AND FLUID MANAGEMENT SYSTEM THEREOF

Systems and methods for controlling fill media in a balloon catheter are disclosed. The system comprises a catheter having an inflatable balloon, a reservoir for fill media, and a first conduit for delivering fill media from the reservoir to the balloon. The system includes a second conduit for returning fill media from the balloon to the reservoir and a pump configured to circulate fill media through the conduits. The system also includes a valve assembly configured for placement in at least three positions. In the first position, fill media is delivered from the reservoir to the balloon to inflate the balloon. In the second position, fill media is drawn out of the balloon and returned to the reservoir. In the third position, fill media circulates through the conduits between the pump and the balloon and is prevented from flowing back to the reservoir. 1. A balloon catheter system , comprising:a balloon catheter including a catheter body and an inflatable balloon coupled to one end thereof; and a reservoir for storing balloon fill media,', 'a first conduit connected between the reservoir and the balloon for delivering the balloon fill media,', 'a second conduit connected between the balloon and the reservoir for returning the balloon fill media from the balloon to the reservoir,', 'a pump disposed along the first conduit and configured to circulate the balloon fill media along a circuit defined by the first and second conduits, and', 'a valve assembly that is disposed along the first and second conduits, with the pump being disposed along the first conduit between the valve assembly and the balloon, the valve assembly being configured for placement in at least a first position, a second position, and a third position, wherein in the first position, the balloon fill media is delivered from the reservoir and pumped into the balloon for inflation thereof, wherein in the second position, the balloon fill media is drawn out of the balloon and pumped back to the ...

DRUG-COATED BALLOON CATHETERS FOR BODY LUMENS

Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. 1. A drug-coated balloon catheter comprising:an elongated balloon having a nominal diameter of 4 mm to 50 mm and a length of 20 mm to 160 mm; and an initial drug load of a therapeutic agent, the therapeutic agent comprising paclitaxel, a paclitaxel analogue, docetaxel, a docetaxel analogue, taxol, a taxol analogue, rapamycin, a rapamycin analogue, sirolimus, a sirolimus analogue, everolimus, an everolimus analogue, tacrolimus, a tacrolimus analogue, mammalian target of rapamycin (mTOR) inhibitors, an mTOR inhibitor analogue, or a combination thereof, and', 'one or more additives, wherein a ratio of the therapeutic agent to the one or more additives in the coating layer is 0.1 to 10;, 'a coating layer overlaying an exterior surface of the balloon, the coating layer comprising'} passing the drug-coated balloon catheter through an introducer sheath into a cylindrical vessel, the cylindrical vessel comprising 0.9% saline at 37° C.,', 'soaking the drug-coated balloon catheter in the saline in the cylindrical vessel for 1 minute,', 'inflating the drug-coated balloon catheter for 1 minute, and', 'withdrawing the drug-coated balloon catheter from the cylinder., 'wherein a soaking procedure for treating a target site in a body lumen with the drug-coated balloon catheter is sufficient for the coating layer to release 37 wt % to 97 wt % of the initial drug load of the therapeutic agent from the coating layer, wherein the soaking procedure consists of'}2. The drug-coated balloon ...

TRANS-ANAL INFLOW CATHETER AND METHOD FOR INTERMITTENTLY TRIGGERING A REFLEX-COORDINATED DEFECATION

A device for transanally introducing an infusion into the rectum of a patient, the device comprising an inflatable balloon having a waisted shape, two terminal sections of larger radius and, a middle section of a reduced radius, and is placed transanally, the distally adjoining radially enlarged balloon section being placed intrarectally and the proximally adjoining radially enlarged balloon section extracorporeally, wherein both balloon ends taper to the dimension of a shaft supporting the balloon and are fixed on the surface of the shaft such that as the balloon is filled, the two enlarged balloon sections move toward each other in opposite axial directions, and wherein the two radially enlarged balloon sections are enlarged relative to the middle balloon section, such that when the balloon is placed transanally, during the filling process the two radially enlarged balloon sections draw down over the middle, balloon section and contact each other, and to a method for filling the catheter balloon. 1. A device for transanally introducing an infusion into the rectum or colon of a patient , said device comprising an inflatable balloon having a waisted shape , comprising two terminal balloon sections of larger radius and generally spherical or discoid shape , and , disposed between them , a middle , tapered balloon section having a reduced radius , the device being adapted to be placed transanally , such that the distally adjoining radially enlarged balloon section is placed intrarectally and the proximally adjoining radially enlarged balloon section extracorporeally , wherein both balloon ends taper a shaft dimension of a catheter shaft supporting the balloon and , beginning at an inflection point of their longitudinal section , are inwardly invaginated , or inverted , and in the inverted or invaginated state are fixed on the outer jacket surface of the catheter shaft such that as the balloon is filled , the two radially enlarged balloon sections move toward each ...

Rectal Catheter Configured For Pediatric Care

A rectal catheter is configured for improved pediatric care. The catheter includes a member that terminates into a rounded tip, a plug mounted about the member, the plug being made of a moldable material, a balloon mounted about the member between the rounded tip and the plug, a conduit that fluidly communicates with the balloon and that extends from the member to enable a pressure source to be operatively connected to the balloon to inflate the balloon, and a pressure relief valve operatively connected to the conduit, the pressure relief valve being configured to open the conduit to atmosphere pressure in response to a pressure in the conduit reaching a predetermined pressure. The predetermined pressure is selected to attenuate significantly risk of bowel perforation in pediatric patients. 1. A rectal catheter comprising:a member that terminates into a rounded tip;a plug made of moldable material, the plug being mounted about the member and configured for bi-directional sliding along the member;a balloon fixedly mounted about the member at a predetermined position that is between the rounded tip and the plug;a conduit that fluidly communicates with the balloon and that extends from the member to enable a pressure source to be operatively connected to the balloon to inflate the balloon; anda pressure relief valve operatively connected to the conduit, the pressure relief valve being configured to open the conduit to atmosphere pressure in response to a pressure in the conduit reaching a predetermined pressure.2. The rectal catheter of further comprising:a disc mounted to the plug.3. The rectal catheter of wherein the disc has a circular shape.4. The rectal catheter of claim 3 , the disc further comprising:a gripping surface on a circumference of the disc.5. The rectal catheter of wherein the disc has a planar surface.6. The rectal catheter of wherein the plug has a conical shape.7. The rectal catheter of claim 1 , the pressure relief valve further comprising:a slit ...

Fill Valve

A fill valve for mediating two-way fluid communication between a medical instrument and a medical device is provided. The fill valve comprises a valve element and a valve housing. The valve element comprises a valve element body extending along a major axis, a valve element first end comprising a recessed internal surface configured to provide a sealing contact engagement with a medical instrument, a valve element second end, and a valve element body external surface. The valve element is resilient and deformable. The valve element also has a hole that extends along the major axis and that is substantially cylindrically symmetrical with respect to the major axis. The valve housing is configured to hold the valve element in place by a circumferential compression fit. An enteral feeding button comprising such a fill valve, and a valve element of such a fill valve, are also provided. 1. A fill valve for mediating two-way fluid communication between a medical instrument and a medical device , the fill valve comprising:(a) a valve element comprising (i) a valve element body extending along a major axis of the valve element, (ii) a valve element first end comprising a recessed internal surface configured to provide a sealing contact engagement with a medical instrument, (iii) a valve element second end opposite the valve element first end, and (iv) a valve element body external surface, wherein the valve element is resilient and deformable and has a hole that extends along the major axis, from the valve element first end, to the valve element second end, through the valve element body, and that is substantially cylindrically symmetrical with respect to the major axis; and(b) a valve housing configured to hold the valve element in place by a circumferential compression fit with the valve element body external surface and to connect to, or be an integral part of, a medical device,wherein:(1) the fill valve is configured to, in the absence of the sealing contact engagement, ...

BALLOON CATHETER DEVICE FOR USE IN AN AORTA OF A RABBIT OR A HUMAN BEING

The invention relates to a balloon catheter device () for use in an aorta of a rabbit or a human being. The device () comprises a balloon catheter (), a syringe (), an actuator (), a pressure sensor (), a balloon retracting unit (), a first control unit () and a second control unit (). The balloon catheter () comprises a flexible tube () and a balloon () at a distal end () of the tube () and the syringe () comprises a chamber () containing a fluid, wherein the chamber () is connected to a proximal end of the tube (). The actuator () is adapted for increasing/decreasing a volume of the fluid contained within the balloon (). The pressure sensor () is adapted for sensing an inflation pressure of the balloon () and the balloon retracting unit () is adapted for retracting the balloon () out of the aorta. The first control unit () is adapted to receive pressure data representing the inflation pressure of the balloon () measured by the pressure sensor () and to control the actuator () depending on the received pressure data, such that the inflation pressure of the balloon () is kept stable at a predefined inflation pressure value, and the second control unit () is adapted to control the balloon retracting unit (), such that the balloon () is retracted out of the aorta at a constant speed. 11. A balloon catheter device () for use in an aorta of a rabbit or a human being , comprising:{'b': '2', 'a balloon catheter (),'}{'b': '3', 'a syringe (),'}{'b': '4', 'an actuator (),'}{'b': '5', 'a pressure sensor (),'}{'b': '6', 'a balloon retracting unit (),'}{'b': '7', 'a first control unit () and'}{'b': '8', 'a second control unit (),'}{'b': 2', '10', '11', '12', '10, 'wherein the balloon catheter () comprises a flexible tube () and a balloon () at a distal end () of the tube (),'}{'b': 3', '16', '16', '10, 'wherein the syringe () comprises a chamber () containing a fluid, wherein the chamber () is connected to a proximal end of the tube (),'}{'b': '4', 'wherein the actuator () is ...

METHOD OF OPERATING AN INTEGRATED BALLOON CATHETER INFLATION SYSTEM

An inflation system having two pressure vessels integrated into a balloon catheter. A pressurized chamber and a vacuum chamber are integrally attached to proximal end of the balloon catheter and activated by a common valve or switch. Pressure or vacuum is selectively transmitted to the balloon depending on the valve/switch position. The working fluid may be air, or a combination of air and saline with an intermediate piston/cylinder assembly. The balloon catheter may be a part of a heart valve delivery system with a balloon-expandable heart valve crimped onto the balloon. 1. A method of storing and actuating a balloon catheter system , comprising: a manifold having internal passages;', 'a sealed pressurized vessel permanently attached to an inflation port in the manifold;', 'a balloon catheter having a balloon on a distal end in fluid communication with an inflation lumen extending through the catheter;', 'a balloon port in the manifold in fluid communication with the balloon catheter inflation lumen; and', 'a control valve on the manifold configured to selectively open and close fluid communication between the balloon port and the inflation port so that a positive pressure differential from the pressurized vessel inflates the balloon;, 'providing an integrated pre-assembled system packaged and sold as a single, unitary system in a unique sterile enclosure, the system includingthe method including:opening the unique sterile enclosure and removing the system;advancing the balloon catheter so that the balloon thereon is positioned at a procedure site within the body; andoperating the control valve on the manifold to open fluid communication between the balloon port and the inflation port and inflate the balloon.2. The method of claim 1 , wherein the balloon catheter system is part of a prosthetic heart valve delivery system including a balloon-expandable heart valve crimped onto the balloon claim 1 , and the step of advancing includes positioning the balloon- ...

Apparatus and methods for administering treatment within a bodily duct of a patient

Apparatus and methods for administering treatment within a bodily duct of a patient. According to one implementation a treatment catheter having an expandable structure disposed at an end thereof is provided that includes an elongate hollow shaft having a one or more first through holes and one or more second through holes spaced axial apart, the one or more first through holes residing beneath the expandable structure. A sleeve positioned along an outer surface of the hollow shaft is moveable between first and second axial positions to respectively permit or inhibit the flow of a treatment agent through the one or more second through holes into the bodily duct. An elongate wire having a seal unit is positioned within an inner lumen of the hollow shaft. The seal unit is moveable between first and second axial positions to respectively permit or inhibit the flow of an inflation medium between a cavity of the expandable structure and the inner lumen of the hollow shaft through the one or more first through holes.

System and method for the effective, reliable and foolproof delivery of controlled amounts of a medical fluid

A method for using CO 2 as a contrast material in medical imaging procedures is disclosed. The method includes providing a source of pressurized CO 2 . The step of providing includes connecting the source of pressurized CO2 to a compressed gas unit for controlling delivery of the CO 2 . The method also includes regulating pressure of the CO 2 delivered by the compressed gas unit, transmitting the pressurized CO 2 from the compressed gas unit to a control valve assembly for delivery to a patient in controlled dosages, and sequentially processing the CO 2 with the control valve assembly and delivering the CO 2 to the patient as a contrast media.

THERAPEUTIC AGENT PREPARATIONS FOR DELIVERY INTO A LUMEN OF THE INTESTINAL TRACT USING A SWALLOWABLE DRUG DELIVERY DEVICE

Embodiments of the invention provide swallowable devices, preparations and methods for delivering therapeutic agents (TA) within the GI tract. Many embodiments provide a swallowable device such as a capsule for delivering TAs into the intestinal wall (IW) or other GI location. Embodiments also provide various TA preparations such as IgG that are configured to be contained within the capsule, advanced from the capsule into the IW and degrade to release the TA into the bloodstream where they exhibit a selected plasma concentration profile which may have selected pharmacokinetic parameters. The preparation can be operably coupled to a delivery means having a first configuration where the preparation is contained in the capsule and a second configuration where the preparation is advanced out of the capsule into the IW. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract. 1. A therapeutic preparation comprising Immunoglobulin G(IgG) , the preparation adapted for insertion into a gastro-intestinal (GI) wall or surrounding tissue after oral ingestion , wherein upon insertion , the preparation degrades to releases IgG into the blood stream from the intestinal wall or surrounding tissue so as to obtain an absolute bioavailability of IgG in a range of about 50 to 68.3 percent.2. The preparation of claim 1 , wherein the surrounding tissue is the peritoneum or peritoneal cavity.3. The preparation of claim 1 , wherein the absolute bioavailability is about 60.7%.4. The preparation of claim 1 , wherein the released IgG exhibits a Tof about 24 hours.5. The preparation of claim 1 , wherein the preparation comprises about 2.3 to 2.38 mg of IgG.6. The preparation of claim 1 , wherein the preparation is adapted for insertion into the wall of the small intestine.7. The preparation of claim 1 , wherein at least a portion of the preparation is in solid form.8. The preparation of claim 1 , ...

PERFUSION BALLOON WITH EXTERNAL VALVE

An apparatus for performing a medical procedure and, in particular, an aortic valvuloplasty, in a vessel for transmitting a flow of fluid. The apparatus includes an inflatable perfusion balloon including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition, the balloon including a plurality of cells in a single cross section and a covering for at least partially covering the cells. A valve associated with the balloon controls the fluid flow within the passage, the valve being arranged external to the passage. The valve may form a tubular extension of the covering, or may be separate from the covering, and may comprise flaps. A spiral covering may also form the valve. 1. An apparatus for performing a medical procedure in a vessel for transmitting a flow of fluid , comprising:an inflatable perfusion balloon including an internal passage for permitting the fluid flow in the vessel while the perfusion balloon is in an inflated condition; anda valve associated with the balloon for controlling the fluid flow within the passage, the valve comprising a plurality of elongated flaps, each of the plurality of flaps for selectively covering an entrance to the passage to control the flow of fluid therein, wherein each flap includes a fixed proximal end;at least one tether for tethering at least one of the flaps to the balloon.2. The apparatus of claim 1 , wherein the flaps each include a distal end that is not connected to the balloon.3. The apparatus of claim 1 , wherein the balloon comprises a generally tapered portion claim 1 , and the flaps extend along the generally tapered portion.4. The apparatus of claim 1 , wherein the at least one flap includes a distal end connected to the balloon by the tether.5. The apparatus of claim 1 , wherein a tether tethers each of the flaps to the balloon.6. The apparatus of claim 1 , wherein the flaps are narrower at the fixed proximal end than at a distal end.7. The ...

Valve Positioning Structure

A valve positioning structure is provided for pressing down a switch arranged in a valve so that fluid is allowed to flow through an inlet opening of the valve when the switch is pressed down in order to control the fluid to flow into/out of at least one bladder. The valve positioning structure includes a casing that receives the valve therein and the casing is provided with a contact member and a manipulation member respectively and movably on upper and lower surfaces of the casing. The contact member and the manipulation member are coupled to each other so that the contact member is operable to drive the manipulation member to move. The manipulation member includes an operation section, where the operation section is movable toward and is enabled to press down the switch when the manipulation member is driven by the contact member to move toward the switch.