СПОСОБ ПОЛУЧЕНИЯ МОЛОЧНОЙ КИСЛОТЫ

Membrane stacks

PROCESS FOR OBTAINING A PROTEIN CONCENTRATE FROM WHEY

... 1313085 Whey protein concentrates J A MEGGLE [trading as MOLKEREI J A MEGGLE MILCHINDUSTRIE] 7 Sept 1971 [30 July 1971] 41658/71 Heading C3H Production of whey protein concentrate by ultrafiltration wherein whey is adjusted to a pH value below the isoelectric point of the whey protein, subjected to ultrafiltration and heated to ensure microbial destruction before and/or after the ultrafiltration. The pH may be adjusted by electrodialysis, removal of cations by ion-exchangers or by the addition of an acid or by using strongly acidifying micro-organisms. The product is preferably neutralized for example using an alkali metal or alkaline earth metal citrate, carbonate or hydroxide and then dried, for example by spray or freeze-drying.

CLEANING METHOD BY NANO-FILTRATION OF A SWEET AQUEOUS SOLUTION, UNIVALENT ONE AND MULTI-VALUED ANIONS AND CATIONS CONTAINING

Sprühgetrocknetes Gemisch humaner Milch-Oligosaccharide

Offenbart ist ein sprühgetrocknetes Pulver, bestehend aus einer Mischung aus strukturell unterschiedlicher Humanmilcholigosaccariden, Methoden für die Produktion des sprühgetrockneten Pulvers sowie die Verwendung für die Zubereitung der Ernährungszusammensetzungen und Ernährungszusammensetzungen mit diesem sprühgetrocknetem Pulver.

Water provision apparatuses and related methods

Apparatuses and methods of treating, storing, and delivering water such that the water may be suitable for washing, rinsing, etc., without forming water spots on a surface or finish. The disclosed systems and methods may treat and store water by a combination of filtration, reverse osmosis, and/or ion exchange.

Method and apparatus for treatment of drinking water

METHODS AND SYSTEMS FOR TREATING PHOSPHOGYPSUM-CONTAINING WATER

Methods for treating phosphogypsum-containing water are disclosed. The water may be treated so as to promote precipitation of one or more target constituents and to facilitate downstream membrane treatment. A coagulant may be added to promote phosphate recovery. Related systems are also disclosed.

METHOD FOR PURIFYING OSES WITHOUT ADJUSTING PH

La présente invention concerne un procédé de purification d'oses issus de l'hémicellulose provenant de biomasses lignocellulosiques, lesdits oses étant contenus dans un hydrolysat acide obtenu par hydrolyse partielle de biomasses lignocellulosiques au moyen d'au moins un catalyseur acide, ledit hydrolysat acide comportant en outre une matrice cellulosique, des résidus solides et/ou des matières en suspension, ledit procédé étant caractérisé en ce qu'il comporte les étapes suivantes : - on élimine, de l'hydrolysat acide, la matrice cellulosique et les résidus solides et/ou les matières en suspension pour obtenir un hydrolysat clarifié; - sans aucun ajout de réactif chimique basique pour augmenter le pH, on soumet ledit hydrolysat clarifié à au moins une étape d'ultrafiltration et/ou à au moins une étape de nanofiltration, de sorte à obtenir un filtrat contenant la majorité des pentoses et un rétentât contenant les espèces susceptibles de précipiter sous l'effet d'une augmentation du pH; ...

METHOD FOR TREATING WATER CONTAINING WATER-INSOLUBLE SUBSTANCE

Provided is a method which can treat water containing a water-insoluble substance in an economically advantageous manner. A method for treating water containing a water-insoluble substance, typified by produced water, using a porous material having a functional group on the surface thereof, preferably a porous material comprising an inorganic oxide. The method comprises: a first step of bringing an aqueous solution containing an ion capable of ion exchanging with the functional group into contact with the surface, thereby attaching the ion onto the surface; and a second step of allowing the water containing the water-insoluble substance to pass through the porous material from the surface of the porous material on which the ion has been attached, thereby removing the water-insoluble substance from the water containing the water-insoluble substance. After the first step and before the second step, a step of burning the porous material under a temperature condition of 300 to 500°C for 1 to ...

LIVER SUPPORT SYSTEM

The present disclosure relates to an artificial, extracorporeal system for liver replacement and/or assistance, comprising a liver dialysis device for conducting hemodialysis on a patient suffering from liver failure, which is characterized in that it comprises a first standard hollow fiber membrane dialyzer which does not allow passage of an essential amount of albumin over the membrane wall and which is perfused with the patient's blood, and a second hollow fiber membrane dialyzer which allows the passage of essential but defined amounts of albumin over the membrane wall and which receives the blood of the first standard hemodialyzer and wherein the filtrate space is closed off from the lumen space of the hollow fibers and is populated by adsorbent material which may comprise one or more different adsorbents.

Container for a filter cartridge and filter set.

Die Erfindung betrifft einen Behälter (1) für eine Filterkartusche (13) sowie einen Filtersatz mit einem derartigen Behälter. Der Behälter (1) weist einen Boden (2) mit einer mit der Aussenseite des Behälters (1) verbindenden Ableitung (8) und eine Seitenwand (3) auf, welche eine Aufnahme (4) für eine Filterkartusche (13) bilden, die mit einem Filtermaterial (20) gefüllt ist. Damit sowohl eine Ionentauscher-Filterkartusche als auch eine Umkehrosmose-Filterkartusche eingesetzt werden kann, ist in der Ableitung (8) neben einer Erweiterung (11), die für den Einsatz einer Umkehrosmose-Filterkartusche ein Drosselventil, z.B. eine Lochblende, aufnehmen kann, auch ein Kugelhahn (12) vorgesehen, der, wenn die eingesetzte Filterkartusche (13) eine Ionentauscher-Filterkartusche ist, geschlossen und andernfalls offen ist.

Container for a filter cartridge and filter set.

Die Erfindung betrifft einen Behälter (1) für eine Filterkartusche (13) sowie einen Filtersatz mit einem derartigen Behälter. Der Behälter (1) weist einen Boden (2) mit einer eine Aufnahme (4) für die Filterkartusche (13) mit der Aussenseite des Behälters (1) verbindenden Ableitung (8) und eine Seitenwand (3) auf, welche eine Aufnahme (4) für eine Filterkartusche (13) bilden, die mit einem Filtermaterial (20) gefüllt ist. Damit sowohl eine Ionentauscher-Filterkartusche als auch eine Umkehrosmose-Filterkartusche eingesetzt werden kann, ist in der Ableitung (8) neben einer Erweiterung (11), die für den Einsatz einer Umkehrosmose-Filterkartusche ein Drosselventil, z.B. eine Lochblende, aufnehmen kann, auch ein Kugelhahn (12) vorgesehen, der, wenn die eingesetzte Filterkartusche (13) eine Ionentauscher-Filterkartusche ist, geschlossen und andernfalls offen ist.

REMOVAL OF IMPURITY AAV VIRUS FROM PREPARATIONS

USOVERShENSTOVANNYI METHOD OF REVERSE OSMOSIS OR NANOFILTRATION FOR CLEANING WATER

METHOD FOR SEPARATING A POPULATION OF PARVOVIRAL VIRIONS FROM A POPULATION OF BACULOVIRAL VIRIONS

DEVICE AND METHOD FOR PRODUCING PURIFIED WATER, IN PARTICULAR FOR THE PHARMACEUTICAL INDUSTRY.

L'invention concerne un système (1) pour la production d'eau purifiée, caractérisé en ce qu'il comprend: - un étage principal comprenant au moins un osmoseur principal (2); et, - un étage secondaire comprenant au moins un osmoseur secondaire (10); l'entrée de l'osmoseur secondaire (10) étant reliée à une sortie (12) pour le concentrat issu d'un processus d'osmose inverse dans l'osmoseur principal (2). L'invention concerne aussi un procédé mettant en œuvre un tel système et un procédé pour augmenter le rendement d'un système de l'art antérieur.

PROCESS FOR PRODUCING A PHOSPHOLIPID CONCENTRATE FROM A DAIRY COMPOSITION

PROCESS FOR the TREATMENT Of WASTE WATER COMING FROM the PREPARATION Of a HALOGENOUS POLYMER

Procédé pour le traitement physico-chimique d'eaux usées provenant d'au moins une unité de préparation d'un polymère halogéné qui comprend au moins une étape de polymérisation d'au moins un monomère halogéné dans un milieu aqueux, au moins une partie des eaux usées soumises au traitement physicochimique ayant préalablement subi une première épuration par au moins un traitement physique et les eaux provenant du traitement physico-chimique étant au moins en partie soumises à une purification finale comprenant une filtration biochimique.

PROCESS OF PURIFICATION BY NANOFILTRATION Of an AQUEOUS SOLUTION SUCREE CONTAINING OF the ANIONS AND CATIONS MONOVALENT AND GENERAL-PURPOSE

La présente invention concerne un procédé de purification par nanofiltration d'une solution aqueuse contenant un ou plusieurs sucres, des cations polyvalents et des anions polyvalents minéraux et/ou des anions d'acides organiques, caractérisé en ce qu'il comprend les opérations : (a) de substitution d'une partie au moins desdits cations polyvalents et/ou desdits anions polyvalents minéraux et anions d'acides organiques respectivement par des cations monovalents et/ou des anions monovalents, pour obtenir une solution aqueuse appauvrie en cations polyvalents et/ou en anions polyvalents minéraux et anions d'acides organiques et contenant lesdits cations monovalents et anions monovalents, et (b) de nanofiltration de la solution résultant de l'opération (a) pour obtenir en tant que rétentat, un jus sucré aqueux enrichi en sucres, en cations polyvalents et en anions polyvalents minéraux et/ou en anions d'acides organiques et en tant que perméat, un effluent aqueux enrichi en anions et cations ...

A microfluidic device for electrochemically regulating the pH of a fluid therein and method for regulating the pH of a fluid in a microfuidic device using the same

xarope de tagatose e galactose

Subsea equipment cleaning system and method

The invention concerns a subsea water processing system comprising an electrochemical unit that uses raw or treated seawater to generate high pH and low pH solutions that are used to clean at least one subsea process apparatus during a cleaning cycle by circulation through the at least one subsea process apparatus via acid or base flow lines connecting the electrochemical unit with the subsea process apparatus on-site.

FORMING DILUTED BRINE WITHOUT ADDITION OF SOFT OR CONTAMINATED WATER IN AN OIL AND GAS TREATMENT FACILITY

Processes and systems form diluted brine from saturated brine without direct addition of soft or contaminated water in an oil and/or gas treatment facility. Water containing salt contaminants is fed to a forward osmosis membrane. The salt contaminants can be cations, anions, carbonate, bicarbonate and combinations thereof. A saturated brine solution is fed to a draw side of the forward osmosis membrane which allows water to pass from the feed side to the draw side and minimizes the passage of the salt contaminants from the feed side to the draw side. A diluted brine solution having a TDS concentration lower than a TDS concentration of the saturated brine solution is removed from the draw side outlet of the forward osmosis membrane. A concentrated contaminated water stream having a TDS concentration higher than a TDS concentration of the contaminated water feed is removed from the feed side outlet of the forward osmosis membrane.

Method and apparatus for treatment of drinking water

The present invention is directed to a method and apparatus for the treatment of drinking water, and more particularly to a treatment process comprising: a) providing raw water to a process tank b) adding a magnetic ion-exchange resin to the process tank to form a raw water/magnetic ion-exchange resin mixture; c) removing treated water from the process tank through a membrane filter, wherein said process tank contains said membrane filter; and d) separating the magnetic ion-exchange resin from the raw water/magnetic ion-exchange resin mixture using a high gradient magnetic filter.

Removing electrolysis from aqueous solutions

... A process for removing strongly ionized electrolytes and weakly ionized acids from aqueous solutions containing a mixture of them comprises subjecting the solutions to electro-deionization successively in two separate units M, N, each unit comprising terminal electrode chambers 2, 4 containing a cathode 23 and an anode 24 respectively and the body of each unit between the electrode chambers comprising alternating diluting and concentrating chambers 12, 14 defined by alternating cation- and anion-exchange permeable membranes C, A, at least the diluting chambers of the first unit M containing a fluid-permeable filler comprising a mixture of strong base anion exchanger and strong acid cation exchanger, at least the diluting chamber of the second unit N containing a fluid-permeable filler consisting of a strong base anion exchanger; passing the feed solution via conduit 30 into the dluting chambers of the first unit M, passing the effluent from ...

Processes and systems for zinc waste reduction

Systems and processes are provided herein for selectively removing zinc from a zinc fluid (14) in order to substantially reduce an amount of zinc waste for disposal in particular settings, such as in an offshore drilling environment. In one embodiment process comprises concentrating a zinc fluid (14) by reverse osmosis (16) and contacting the concentrate (22) with an anionic ion exchange resin (18). In another embodiment process comprises treating a zinc fluid only with an anionic ion exchanger resin. In yet another embodiment the process focuses on multipass treatment with reverse osmosis.

Subsea equipment cleaning system and method

The invention concerns a subsea water processing system comprising an electrochemical unit that uses raw or treated seawater to generate high pH and low pH solutions that are used to clean at least one subsea process apparatus during a cleaning cycle by circulation through the at least one subsea process apparatus via acid or base flow lines connecting the electrochemical unit with the subsea process apparatus on-site.

Removal of contaminating viruses from AAV preparations

The present invention relates to a separation of viruses of an essentially spherical shape from viruses with a rod-like shape that are comprised in a sample, wherein the sample comprising the viruses is subjected to filtration.

METHOD FOR PRODUCING A PHOSPHOLIPID CONCENTRATE FROM A DAIRY COMPOSITION

L'invention porte principalement sur un procédé de fabrication d'un concentré de phospholipides issus d'une composition laitière liquide comprenant au moins des caséines et des phospholipides, qui est caractérisé en ce qu'il comprend au moins les étapes de : - passage de la composition laitière dans une colonne à échange d'ions sur résine cationique, - concentration des phospholipides de la composition laitière appauvrie en calcium par microfiltration à gradient de pression transmembranaire contrôlé, et - récupération du rétentat de la microfiltration et obtention d'un concentré de phospholipides.

SYSTEMS AND METHODS FOR WATER FILTRATION

A water filtration systems may comprise an under the sink RO water filtration system that is plumed into a building's water supply. For example, the water filtration systems may include an RO device at least partially installed underneath a sink, with the tap water connection plumbed directly to the sink cold water supply line, and a waste water drain line connected directly to the sink drain, such as the p-trap.

CLEANING FLUID MEDIUM BY MEANS OF DIRECT OSMOSIS, ION EXCHANGE AND REPEATED CONCENTRATION

For the production of ultra-pure water method

For purifies mellowly method and device

Process of purification of the amino-acids

Improvements with the processes of demineralization of the aqueous liquids by electrodialysis

METHOD FOR PURIFYING AN AQUEOUS LACTIC ACID SOLUTION FROM HIGH CARBOHYDRATE BY-PRODUCTS

Procédé de purification d'une solution aqueuse d'acide lactique au départ de sous-produits à haute teneur en hydrates de carbone La présente invention se rapporte à un procédé de purification d'une solution aqueuse 10 d'acide lactique, obtenue par fermentation d'une source d'hydrate de carbone contenant une part de sucres non fermentescibles tels que des oligosaccharides (DPn). Figure 1. 2012/0673 ...

SEPARATION OF MG2+ IONS FROM SEA-AND BRACKISH WATER FOR THE PURPOSE OF RE-MINERALIZATION OF WATER AND WASTEWATER

System comprising: DU (desalination unit); separation unit (SU) providing divalent ions enriched brine, and monovalent ions enriched permeate, and configured to: split salty water between DU and SU, add permeate to DU, and add brine to desalinated water from DU.

PROCESS AND SYSTEM FOR TREATING WATER

A process for treating water, in particular for producing ultrapure water, is described, in which a water stream is purified in a reverse osmosis unit, wherein the water stream is subjected to a pretreatment having the steps (1) partial exchange of the cations present in the water stream for H+ ions and (2) substantially complete exchange of the anions present in the water stream against OH- ions, and the water stream obtained from the pretreatment is passed directly into the reverse osmosis unit. In addition, a system is described in which such a process may be carried out.

Systems and Methods for Purifying Solvents

The present disclosure is directed to methods and systems of purifying solvents. The purified solvents can be used for cleaning a semiconductor substrate in a multistep semiconductor manufacturing process.

Process and system for treating water

A process for producing ultrapure water, in which a stream of water is purified in a reverse osmosis device, wherein the water stream is subject to pretreatment including splitting the water stream into at least two partial streams, partial exchange of cations present in at least one of the partial streams for H+ ions by a cation exchanger operated in the H+ mode, and complete exchange of the anions present in at least one further of the partial streams for OH ions by a softener operative in parallel to the cation exchanger, and treating the partial streams treated by the cation exchanger and the softener by at least one anion exchanger operating in the OH mode, and wherein the water stream obtained from the pretreatment is fed into the reverse osmosis device.

SEPARATION OF NEUTRAL OLIGOSACCHARIDES FROM FERMENTATION BROTH

The present invention relates to the separation and isolation of neutral human milk oligosaccharides (HMOs) from the reaction mixture in which they are produced.

Chemical liquid purification method

An object of the present invention is to provide a chemical liquid purification method which makes it possible to obtain a chemical liquid having excellent defect inhibition performance. The chemical liquid purification method according to an embodiment of the present invention is a chemical liquid purification method including obtaining a chemical liquid by filtering a substance to be purified containing an organic solvent by using two or more kinds of filters having different pore sizes, in which a supply pressure P1of the substance to be purified supplied to a filter Fmaxhaving a maximum pore size X1among the two or more kinds of filters and a supply pressure P2of the substance to be purified supplied to a filter Fminhaving a minimum pore size X2among the two or more kinds of filters satisfy P1>P2.

СПОСОБ ОБРАБОТКИ СТОЧНЫХ ВОД, ОБРАЗУЮЩИХСЯ ПРИ ПОЛУЧЕНИИ ГАЛОГЕНИРОВАННОГО ПОЛИМЕРА

FIELD: technological processes. SUBSTANCE: invention can be used in production of halogenated polymers. Method of treating waste water formed when producing halogenated polymers in aqueous medium, includes a step of physicochemical treatment of at least one part of said waste water, wherein one part is subjected to treatment using one physical treatment; a final treatment step including biochemical filtration using a membrane bioreactor of at least one part of water formed after physicochemical treatment. Physicochemical treatment involves mixing waste water, as well as clarification in combination with use of coagulants and flocculants. Physical treatment includes filtration, thermal treatment, including a step of evaporating waste water to produce evaporated waste water and step of condensing evaporated waste water to produce condensed waste water or treatment, which is a combination of filtration and thermal treatment. EFFECT: method ensures reduction of fresh water consumption when producing a halogenated polymer and efficient recycling of purified waste water. 14 cl, 1 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 632 007 C2 (51) МПК C02F 9/14 (2006.01) C02F 1/52 (2006.01) C02F 3/06 (2006.01) C02F 101/30 (2006.01) C02F 103/38 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2013125564, 28.10.2011 (24) Дата начала отсчета срока действия патента: 28.10.2011 Дата регистрации: (72) Автор(ы): КЕЙШ, Роланд (BE), ВАН ВЕЙНБЕРГ, Жак (BE), ДОМПА, Дирк Хюго, Йозеф (BE) Приоритет(ы): (30) Конвенционный приоритет: (56) Список документов, цитированных в отчете о поиске: US 2008/0146753 A, 19.06.2008. RU 04.11.2010 FR 1059081 (45) Опубликовано: 02.10.2017 Бюл. № 28 2184087 C2, 27.06.2002. SU 1736944 А, 30.05.1992. WO 2006/130163 A1, 07.12.2006. CN 101343132 A, 14.01.2009. CN 101525198 A, 09.09.2009. (85) Дата начала рассмотрения заявки PCT на национальной фазе: 04.06.2013 (86) Заявка PCT: EP 2011/069005 (28.10. ...

Process for removing mineral constituents from an aqueous liquid

Aqueous liquid is passed through an ion exchanging unit where a multivalent ion is removed therefrom, then through a multi-cell electrodialyzing unit where a monovalent ion is removed therefrom, the spent ion-exchanger of the first stage being regenerated at least in part by the concentrated solution produced in the concentration cells of the second stage. As applied to the deionizing of water, calcium and magnesium may be removed by ion exchange and sodium by electrodialysis, the concentrated solution of sodium salts produced being used to regenerate the ion-exchange medium. An additional regenerating liquid may also be used; this may consist of raw water which has been concentrated so that most of the calcium salts are precipitated while alkali salts remain in solution. Specification 682,703, 736,888, 750,238 and 904,913 are referred to.ALSO:Aqueous liquid is passed through an ion exchanging unit where a multivalent ion is removed therefrom, then through a multi-cell electrodialyzing ...

ELECTRODIALYTIC PROCESS FOR PRODUCING ITACONIC ACID AND ITS SALTS

... 1397150 Itaconic acid T MIYAJIMA 17 Nov 1972 [19 Nov 1971 18 March 1972] 53298/72 Heading C2C [Also in Division C7] In a process for producing itaconic acid or salts thereof a microorganism producing itaconic acid is cultured in a nutriant medium, is treated to remove high M.W. (greater than 1000) compounds and the solution neutralized to yield an itaconic acid salt containing solution. The removal of high M.W. compounds may be by ultrafiltration or by reverse osmosis. The solution may be neutralized by treatment with a cation exchange resin followed by treatment with a base. The neutralized solution is concentrated by electrodialysing into an alkali metal salt solution. Itaconic acid or alkali metal salt thereof is crystallized out by concentrating the solution or by adding a mineral acid. The dialysate, depleted in itaconic acid, may be acidified by treatment with a cation exchange resin to convert any itaconic acid salts to the free acid and the acidified dialysate may be recycled into ...

Pasteurization system and method for operating a pasteurization plant

Die Erfindung betrifft ein Verfahren zum Betreiben einer Pasteurisierungsanlage, bei welchem mit Lebensmitteln befüllte und verschlossene Behältnisse in einer oder mehreren Behandlungszone(n) mit einer temperierten, wässrigen Behandlungsflüssigkeit behandelt werden. Zumindest ein Teil der Behandlungsflüssigkeit wird zur Wiederverwendung in mindestens einem Umlaufkreislauf um die Behandlungszone( n) geführt. Eine Teilmenge der in dem mindestens einen Umlaufkreislauf geführten Behandlungsflüssigkeit wird entnommen, und einer Reinigungsvorrichtung, umfassend eine Membranfiltrationsvorrichtung zugeführt. Hierbei wird eine Durchflussrate durch die Membranfiltrationsvorrichtung fortwährend mit einer Sensorvorrichtung überwacht. Durch Verstellen einer Durchflussregelstellung mindestens eines verstellbaren Durchflussregulierungsmittels wird ein Volumenstrom durch die Membranfiltrationsvorrichtung beeinflusst. Der wenigstens eine Teilstrom wird anschließend wieder in einen Umlaufkreislauf oder eine ...

METHODS TO PRODUCE A HUMAN PLASMA-DERIVED IGG PREPARATION ENRICHED IN BRAIN DISEASE-RELATED NATURAL IGGS

The present invention provides, among other aspects, methods for the manufacture of plasma-derived immunoglobulin G compositions highly enriched for anti brain disease related protein antibodies (e.g., anti-Ap, anti-RAGE, and anti-a-synuclein antibodies). Advantageously, the methods provided do not affect the manufacturing processes or capabilities for producing plasma-derived IgG therapeutics. Plasma-derived IgG compositions that are highly enriched for anti-brain disease related protein antibodies (e.g., anti-Ap, anti-RAGE, and anti-a-synuclein antibodies), as also provided here. Methods for the treatment of brain diseases and disorders by administration of plasma-derived IgG compositions highly enriched for anti-brain disease related protein antibodies (e.g., anti-Ap, anti-RAGE, and anti-a-synuclein antibodies), are also provided.

Method and system for preparing battery grade and high purity grade lithium hydroxide and lithium carbonate from high-impurity lithium sources

Abstract The invention discloses a method and a system for preparing battery grade and high purity grade lithium hydroxide and lithium carbonate from high-impurity lithium sources. The method comprises steps for preparation of a refined lithium salt solution, preparation of battery grade lithium hydroxide, preparation of high purity grade lithium hydroxide, preparation of high purity grade lithium carbonate and preparation of battery grade lithium carbonate. The system comprises a refined lithium salt solution preparation subsystem, a battery grade lithium hydroxide preparation subsystem, a high purity grade lithium hydroxide preparation subsystem, a high purity grade lithium carbonate preparation subsystem and a battery grade lithium carbonate preparation subsystem arranged in turn according to production sequence. To treat the high-impurity lithium sources varying in lithium contents, impurity categories and impurity contents, the invention proposes differentiated combinations of physical ...

Recovery of lithium from an acid solution

Methods of recovering lithium from a lithium source or a lithium-containing material using low pH solutions and membrane technologies to purify and concentrate the recovered lithium. The lithium sources may include a spent lithium-ion battery /cell, a lithium- containing mineral deposit, or other lithium containing materials. The processes described herein recovery the lithium after digestion of the lithium-containing material with a low pH solution through one or more acid-stable, semipermeable membranes.

Recovery of lithium from an acid solution

Methods of recovering lithium from a lithium source or a lithium-containing material using low pH solutions and membrane technologies to purify and concentrate the recovered lithium. The lithium sources may include a spent lithium-ion battery /cell, a lithium- containing mineral deposit, or other lithium containing materials. The processes described herein recovery the lithium after digestion of the lithium-containing material with a low pH solution through one or more acid-stable, semipermeable membranes.

METHODS AND SYSTEMS FOR TREATING PHOSPHOGYPSUM-CONTAINING WATER

Methods for processing pretreated phosphogypsum wastewater are disclosed. The pretreated wastewater may be subjected to electrodialysis involving at least one monovalent cation selective membrane. Further downstream membrane treatment may be applied. Upstream precipitation and air-stripping techniques may optionally also be employed. Related systems are also disclosed.

PROCESS OF PRODUCING 1,4-BUTANEDIOL

A process produces 1,4-butanediol by purifying 1,4-butanediol originated from a fermentation broth, by which process 1,4-butanediol having properties suited as a material of producing a polyester is obtained, which 1,4-butanediol enables to reduce by-production of tetrahydrofuran during the esterification reaction and to reduce the delay in polymerization. The process of producing 1,4-butanediol includes adding an alkaline substance other than an ammonia or an amine to an aqueous 1,4-butanediol-containing solution originated from a fermentation broth; distilling the resulting mixture; and recovering a 1,4-butanediol- containing solution from the vapor flow.

OSMOTIC SEPARATION SYSTEMS AND METHODS

Separation processes using osmotically driven membrane systems are disclosed generally involving the extraction of solvent from a first solution to concentrate solute by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane.

LIVER SUPPORT SYSTEM

The present disclosure relates to an artificial, extracorporeal system for liver replacement and/or assistance, comprising a liver dialysis device for conducting hemodialysis on a patient suffering from liver failure, which is characterized in that it comprises a first standard hollow fiber membrane dialyzer which does not allow passage of an essential amount of albumin over the membrane wall and which is perfused with the patient's blood, and a second hollow fiber membrane dialyzer which allows the passage of essential but defined amounts of albumin over the membrane wall and which receives the blood of the first standard hemodialyzer and wherein the filtrate space is closed off from the lumen space of the hollow fibers and is populated by adsorbent material which may comprise one or more different adsorbents.

spray dried mixture of oligosaccharides of human milk

mÉtodo de purificar um fluido que contÉm uma primeira espÉcie-alvo, uma segunda espÉcie-alvo e uma espÉcie nço-alvo

Method for detecting albumin based on colorimetric and system thereof

PROCESSES FOR PREPARING OR RECOVERING ACETALS OR KETALS BY MEANS OF PERVAPORATION

The process of the present invention comprises reacting an aldehyde or ketone with an alcohol in the presence of a solid acid, and removing removing water and methanol from the reaction product by pervaporation, characterized in that a membrane having a flux density for water of 0.04 to 2.8 kg/(hm2) is used to remove the water and another membrane having a flux density for methanol of 2.0 to 100 kg/(hm2) is used to remove the methanol.

CONVERSION OF SEAWATER TO DRINKING WATER AT ROOM TEMPERATURE

An apparatus and method for converting seawater to drinking water at room temperature aoci normal atmospheric pressure. The conversion is accomplished using the processes of osmosis, ammonia stripping: ion exchange, and breakpoint chlojlnation, which provide a low-cost alternative to traditional seawater conversion methods.

A SYSTEM AND METHOD FOR THE TREATMENT OF HYDRAULIC FRACTURING BACKFLOW WATER

Hydraulic fracturing produces backflow water that is high in total dissolved solids, hardness and silica. A system to treat backflow water has an electrical separation unit (10) and a reverse osmosis (RO) unit (20). The electrical separation unit (10) may comprise an electrodialysis device (ED), an electrodialysis reversal (EDR) device or a supercapacitive desalination (SCD) device, or a combination thereof. The electrical separation unit (10) may be combined with a precipitation unit and reduces the TDS and hardness of the backflow water. The RO unit (20) reduces the silica concentration of the backflow water. A pre-treatment unit may further condition backflow water treated in the electrical separation unit to inhibit fouling in the RO unit (20). The treated backflow water may be suitable for reuse in hydraulic fracturing or discharge.

REMOVAL OF CONTAMINATING VIRUSES FROM AAV PREPARATIONS

The present invention relates to a separation of viruses of an essentially spherical shape from viruses with a rod-like shape that are comprised in a sample, wherein the sample comprising the viruses is subjected to filtration. 1. A method for separating a population of parvoviral virions from a population of baculoviral virions , comprising filtrating a sample comprising populations of parvoviral and baculoviral virions over a filter in tangential flow filtration modus , wherein the filter has a nominal pore size of 30-40 nm.2. The method according to claim 1 , wherein the sample claim 1 , prior to filtration claim 1 , is prepurified using a method selected from the group consisting of a density gradient claim 1 , a prefiltration claim 1 , a chromatography step claim 1 , and combinations of these methods claim 1 , resulting in a pre-purified sample.3. The method according to claim 1 , wherein the parvovirus is an adeno-associated virus.4. The method according to claim 1 , wherein the baculovirus is Autographa californica multicapsid nucleopolyhedrovirus (AcmNPV).5. The method according to claim 1 , wherein the filter is a virus filter or an ultrafilter.6. The method according to claim 1 , wherein the filter is a surface and/or a depth filter.7. The method according to claim 1 , wherein the filter comprises a material selected from the group consisting of cuprammonium-regenerated cellulose claim 1 , polyvinylidenefluoride claim 1 , polysulfone claim 1 , polytetrafluoroethylene claim 1 , polypropylene claim 1 , modified or unmodified polyethersulfone claim 1 , cellulose acetate claim 1 , cellulose nitrate claim 1 , polyamide and regenerated cellulose.8. The method according to claim 1 , wherein the filter has a nominal pore size of 32-38 nm.9. The method according to claim 1 , wherein the filter comprises cuprammonium-regenerated cellulose.10. The method according to claim 9 , wherein the filter comprises cuprammonium-regenerated cellulose hollow fibers.11. The ...

Method for detecting albumin based on colorimetric assay and system thereof

A method for detecting albumin based on a colorimetric assay and a system thereof are disclosed. Gold nanoparticles are added into the sample preparing device having a sample without spectroscopic tags, wherein the sample without spectroscopic tags is formed as the alkaline solution to avoid the interference substances adhering on the gold nanoparticles. The gold nanoparticles are concentrated by using the microfluidic concentrator with the circular ion exchange membrane by applying an external electric field across two electrodes. The image of the concentrated gold nanoparticles is captured by the image capturing device for measuring the saturation intensities of the image, wherein there is a relation between the saturation intensities and the concentration of the albumin in the sample without spectroscopic tags. The concentration of the albumin of the sample without spectroscopic tags is obtained by the relation and the measured saturation intensities.

METHOD FOR QUALIFYING A NON-PARTICULATE ADSORBENT BY MEANS OF A SECONDARY REACTION

СПОСОБ ПОЛУЧЕНИЯ МОЛОЧНОЙ КИСЛОТЫ

Изобретение относится к биотехнологии. Предложен способ получения чистой молочной кислоты из сывороточного побочного продукта с высоким содержанием лактозы и минералов, например из сывороточного пермеата, концентрированного сывороточного пермеата и делактозного сывороточного пермеата, которые содержат по меньшей мере 30 г/л лактозы и по меньшей мере 1500 м.д. хлорида. Нейтрализуют сывороточный побочный продукт основным гидроксидом металла с получением осадка, содержащего кальций и фосфат. Отделяют осадок с получением осветленного сывороточного побочного продукта. Инкубируют осветленный сывороточный побочный продукт с бактериями, способными к биопревращению лактозы в молочную кислоту. Получают ферментативный бульон, содержащий молочную кислоту в форме соли. Подкисляют бульон для высвобождения молочной кислоты из соли молочной кислоты. Удаляют осадок, полученный при подкислении. Обрабатывают подкисленный ферментативный бульон для выделения чистой молочной кислоты посредством удаления остаточных ...

Бессточная система оборотного водоснабжения воды для теплоиспользующего оборудования

Изобретение может быть использовано в энергетике, химии и нефтепереработке. Бессточная система оборотного водоснабжения 1 для теплоиспользующего оборудования включает градирню 2, трубопроводы 4 и 5 подпиточной воды и продувочной воды, соответственно, и химводоочистку 6. Химводоочистка 6 включает предочистку 7, Na-катионитный фильтр 8 с трубопроводом 21 его регенерации, бак 15 концентрата установки обратного осмоса второй ступени, бак 9 сбора Na-катионированной воды, установки 12 и 13 обратного осмоса, соответственно первой и второй ступеней по концентрату, трубопровод 17 питательной воды установки 12. Трубопровод 24 пермеата установок 12 и 13 подключен к трубопроводу 3 циркуляционной воды. Трубопровод 20 концентрата установки 13 подключен к баку 15, трубопровод 22 отработанного регенерационного раствора Na-катионитного фильтра подключен к системе 25 подачи его на распыливание в паровоздушном потоке, выходящем из градирни 2. Трубопровод 23 отмывочной воды Na-катионитного фильтра подключен ...

Processes and systems for zinc waste reduction

Methods and systems for treating phosphogypsum-containing water

Methods for processing pretreated phosphogypsum wastewater are disclosed. The pretreated wastewater may be subjected to electrodialysis involving at least one monovalent cation selective membrane. Further downstream membrane treatment may be applied. Upstream precipitation and air-stripping techniques may optionally also be employed. Related systems are also disclosed.

Spray-dried 3-fucosyllactose

Disclosed is a method for the manufacture of a spray-dried powder consisting essentially of 3-fucosyllactose, the spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions containing the spray-dried powder.

Methods and systems for treating phosphogypsum-containing water

Methods for treating phosphogypsum-containing water are disclosed. The water may be treated so as to promote precipitation of one or more target constituents and to facilitate downstream membrane treatment. A coagulant may be added to promote phosphate recovery. Ammonia may optionally be removed. Related systems are also disclosed.

Method for treating produced water

A method for treating produced water in a system for treating wastewater is disclosed. The system includes a reverse osmosis unit for removing dissolved solids. The reverse osmosis unit produces a permeate and concentrate. To reduce the fouling potential of the membranes associated with the reverse osmosis unit and/or to increase membrane lifetime and/or to increase system recovery, at least a portion of the concentrate is recycled and mixed with the wastewater stream at a point upstream of the reverse osmosis unit.

METHOD FOR PURIFYING BY NANOFILTRATION AN AQUEOUS SUGARY SOLUTION CONTAINING MONOVALENT AND POLYVALENT ANIONS AND CATIONS

Subsea equipment cleaning system and method

The invention concerns a subsea water processing system comprising an electrochemical unit that uses raw or treated seawater to generate high pH and low pH solutions that are used to clean at least one subsea process apparatus during a cleaning cycle by circulation through the at least one subsea process apparatus via acid or base flow lines connecting the electrochemical unit with the subsea process apparatus on-site.

A method of producing lactic acid

A process for producing pure lactic acid from a whey by-product rich in lactose and minerals, for example delactosed why permeate or concentrated whey permeate, is described. The method comprises upstream steps of neutralising the whey by-product with a basic metal hydroxide to form a precipitate comprising calcium and phosphate, and separating the precipitate from the whey by-product to provide a clarified whey by-product. The clarified whey by-product is fermentated by a bacterium capable of bioconversion of lactose to lactic acid to provide a fermentation broth containing a lactic acid salt. In the downstream steps, the fermentation broth is acidified to release lactic acid from the lactic acid salt, precipitate from the broth produced by acidification is removed, and the acidified fermentation broth is treated to recover pure lactic acid by removal of residual salts, and water, and optionally protein. The process of the invention produces lactic acid having a purity of 80-98% and an ...

Liver support system

The present disclosure relates to an artificial, extracorporeal system for liver replacement and/or assistance, comprising a liver dialysis device for conducting hemodialysis on a patient suffering from liver failure, which is characterized in that it comprises a first standard hollow fiber membrane dialyzer which does not allow passage of an essential amount of albumin over the membrane wall and which is perfused with the patient's blood, and a second hollow fiber membrane dialyzer which allows the passage of essential but defined amounts of albumin over the membrane wall and which receives the blood of the first standard hemodialyzer and wherein the filtrate space is closed off from the lumen space of the hollow fibers and is populated by adsorbent material which may comprise one or more different adsorbents.

A manufacturing facility for the production of biopharmaceuticals

A manufacturing facility for the continuous production of biopharmaceuticals integrated with single-use disposable technology.

METHOD FOR PURIFYING OSES WITHOUT ADJUSTING PH

La présente invention concerne un procédé de purification d'oses consistant en des pentoses et étant contenus dans un hydrolysat acide, le procédé comportant les étapes suivantes : - on élimine, de l'hydrolysat acide, la matrice cellulosique et les résidus solides et/ou les matières en suspension pour obtenir un hydrolysat clarifié ; - sans aucun ajout de réactif chimique basique pour augmenter le pH, on soumet l'hydrolysat clarifié à au moins une étape d'ultrafiltration et/ou à au moins une étape de nanofiltration au moyen d'une membrane organique, de sorte à obtenir un filtrat contenant la majorité des pentoses et le catalyseur acide non neutralisé, et un rétentât contenant les espèces susceptibles de précipiter sous l'effet d'une augmentation du pH ; et - on traite le filtrat par au moins une étape d'électrodialyse de sorte à récupérer le catalyseur acide dans une solution enrichie en acide, et à obtenir un filtrat désacidifié.

IMROVED REVERSE OSMOSIS OR NANOFILTRATION PROCESS FOR CLEANING WATER

A system for cleaning feed water of variable quality, the system comprising an inlet for selectively delivering feed water (FW) to one or other of at least two feed chambers (2,4), each feed chamber having a delivery pipe (2i, 4i) for delivering feed water to a reverse osmosis or nanofiltration (8); a pump (6) to deliver the feed water from one of the chambers (2, 4) through its associated delivery pipe (2i, 4i) to the reverse osmosis or nanofiltration (8) to create a concentrated feed stream and a product water stream (PW);return pipes (2R, 4R) for selectively returning the concentrated feed stream to one or other of the at least two feed chambers (2, 4); a product water outlet for removal of the product water (PW); and means for switching the delivery of the concentrated feed stream between the selectable return pipes (2R, 4R) upon detection of a predetermined reduction in the efficiency of the RO or NF process within one or other of the feed chambers (2, 4). The pressure of the concentrated ...

REMOVAL OF CONTAMINATING VIRUSES FROM AAV PREPARATIONS

The present invention relates to a separation of viruses of an essentially spherical shape from viruses with a rod-like shape that are comprised in a sample, wherein the sample comprising the viruses is subjected to filtration.

OSES PURIFICATION PROCESS.

METHOD AND APPARATUS FOR PURIFYING ALCOHOL

Improvements in or relating to nuclear reactor installations

METHOD FOR TREATING PRODUCED WATER

METHODS TO PRODUCE A HUMAN PLASMA-DERIVED IGG PREPARATION ENRICHED IN BRAIN DISEASE-RELATED NATURAL IGGS

The present invention provides, among other aspects, methods for the manufacture of plasma-derived immunoglobulin G compositions highly enriched for anti-brain disease related protein antibodies (e.g., anti-Aβ, anti-RAGE, and anti-α-synuclein antibodies). Advantageously, the methods provided do not affect the manufacturing processes or capabilities for producing plasma-derived IgG therapeutics. Plasma-derived IgG compositions that are highly enriched for anti-brain disease related protein antibodies (e.g., anti-Aβ, anti-RAGE, and anti-α-synuclein antibodies), as also provided here. Methods for the treatment of brain diseases and disorders by administration of plasma-derived IgG compositions highly enriched for anti-brain disease related protein antibodies (e.g., anti-Aβ, anti-RAGE, and anti-α-synuclein antibodies), are also provided.

Separation of oligosaccharides from fermentation broth

The present invention relates to the isolation and purification of sialylated oligosaccharides from an aqueous medium in which they are produced.

METHOD FOR PRODUCING A PHOSPHOLIPID CONCENTRATE FROM A DAIRY COMPOSITION

The method for producing a phospholipid concentrate derived from a liquid dairy composition comprising at least caseins and phospholipids, includes at least the steps of: —passing the dairy composition into an ion-exchange column on a cationic resin, —concentrating the phospholipids of the calcium-depleted dairy composition by means of controlled transmembrane pressure gradient microfiltration, and —recovering the retentate from the microfiltration and obtaining a phospholipid concentrate.

Manufacturing facility for the production of biopharmaceuticals

A manufacturing facility for the continuous production of biopharmaceuticals integrated with single-use disposable technology.

Methods to produce a human plasma-derived IgG preparation enriched in brain disease-related natural iggs

The present invention provides, among other aspects, methods for the manufacture of plasma-derived immunoglobulin G compositions highly enriched for anti-brain disease related protein antibodies (e.g., anti-Aβ, anti-RAGE, and anti-α-synuclein antibodies). Advantageously, the methods provided do not affect the manufacturing processes or capabilities for producing plasma-derived IgG therapeutics. Plasma-derived IgG compositions that are highly enriched for anti-brain disease related protein antibodies (e.g., anti-Aβ, anti-RAGE, and anti-α-synuclein antibodies), as also provided here. Methods for the treatment of brain diseases and disorders by administration of plasma-derived IgG compositions highly enriched for anti-brain disease related protein antibodies (e.g., anti-Aβ, anti-RAGE, and anti-α-synuclein antibodies), are also provided.

Method of producing lactic acid

A process for producing pure lactic acid from a whey by-product rich in lactose and minerals, for example delactosed why permeate or concentrated whey permeate, is described. The method comprises upstream steps of neutralising the whey by-product with a basic metal hydroxide to form a precipitate comprising calcium and phosphate, and separating the precipitate from the whey by-product to provide a clarified whey by-product. The clarified whey by-product is fermentated by a bacterium capable of bioconversion of lactose to lactic acid to provide a fermentation broth containing a lactic acid salt. In the downstream steps, the fermentation broth is acidified to release lactic acid from the lactic acid salt, precipitate from the broth produced by acidification is removed, and the acidified fermentation broth is treated to recover pure lactic acid by removal of residual salts, and water, and optionally protein. The process of the invention produces lactic acid having a purity of 80-98% and an ...

Method for separation and purification of n-acetylglucosamine

The disclosure relates to a method for separation and purification of N-acetyl-glucosamine, and belongs to the technical field of biological engineering. In the disclosure, a raw material solution containing N-acetyl-glucosamine is obtained by microbial fermentation or by hydrolyzing the chitin. The raw material solution is subjected to flocculation pretreatment, and continuous centrifugation or pressure filtration is performed to remove suspended solids such as microorganisms, proteins and polysaccharides to obtain clear liquid. Double-stage ion exchange chromatography is performed to remove impurities such as charged organic molecules and inorganic salts. Membrane concentration is performed to efficiently remove water to improve the concentration of the target product. Spray drying or further evaporation concentration and crystallization are performed. Finally drying is performed to obtain an N-acetyl-glucosamine crystal of which the purity is more than 99%.

Verfahren zur Reinigung von auf synthetischem Wege hergestellten Aminosaeuren

Integrated device for liver support system

The present disclosure relates to an extracorporeal system for liver dialysis, comprising a filter device having combined therein hollow fibers with integrated ion-exchange particles and hydrophobic adsorbent particles in the filtrate space. The system can be used for the treatment of acute liver failure and acute-on-chronic liver failure.

METHODS TO PRODUCE A HUMAN PLASMA-DERIVED IGG PREPARATION ENRICHED IN BRAIN DISEASE-RELATED NATURAL IGGS

The present invention provides, among other aspects, methods for the manufacture of plasma-derived immunoglobulin G compositions highly enriched for anti brain disease related protein antibodies (e.g., anti-Ap, anti-RAGE, and anti-a-synuclein antibodies). Advantageously, the methods provided do not affect the manufacturing processes or capabilities for producing plasma-derived IgG therapeutics. Plasma-derived IgG compositions that are highly enriched for anti-brain disease related protein antibodies (e.g., anti-Ap, anti-RAGE, and anti-a-synuclein antibodies), as also provided here. Methods for the treatment of brain diseases and disorders by administration of plasma-derived IgG compositions highly enriched for anti-brain disease related protein antibodies (e.g., anti-Ap, anti-RAGE, and anti-a-synuclein antibodies), are also provided.

METHODS AND SYSTEMS FOR TREATING PHOSPHOGYPSUM-CONTAINING WATER

Methods for treating phosphogypsum-containing water are disclosed. The water may be treated so as to promote precipitation of one or more target constituents and to facilitate downstream membrane treatment. A coagulant may be added to promote phosphate recovery. Ammonia may optionally be removed. Related systems are also disclosed.

METHODS AND SYSTEMS FOR TREATING PHOSPHOGYPSUM-CONTAINING WATER

Methods for processing pretreated phosphogypsum wastewater are disclosed. Precipitation of select constituents may be promoted to control a hardness level of the pretreated wastewater. Ammonia may then be removed from the process stream via reverse osmosis. A membrane contactor and/or polishing unit(s) may optionally be used. Related systems are also disclosed ...

MEMBRANE STACKS

A process for preparing a membrane stack comprising the steps of: (i)interposing a curable adhesive between alternate anion exchange membranes and cation exchange; and (ii)curing the adhesive; CHARACTERISED IN THAT said adhesive, when cured, has a Shore A hardness of less than 70 and an elongation at break of at least 50%.

PURIFICATION DEVICE AND PURIFICATION METHOD FOR WATER UTILIZING FILTER CARTRIDGES

A purification device for water has a housing with a longitudinal axis, an upper and a lower end and a substantially round cross section. The device includes a first receptacle, arranged parallel to the longitudinal axis of the housing, for a first purification medium, and a second receptacle, which is also arranged parallel to the longitudinal axis of the housing, for a second purification medium. The receptacle for the second purification medium is arranged eccentrically with respect to the longitudinal axis of the housing. 1. Purification device for water , comprising:a housing having a longitudinal axis, an upper and a lower end and a substantially round cross section,a first receptacle, arranged parallel to the longitudinal axis of the housing, for a first purification medium, and a second receptacle, arranged parallel to the longitudinal axis of the housing, for a second purification medium,wherein the second receptacle for the second purification medium is arranged eccentrically with respect to the longitudinal axis of the housing.2. Purification device claim 1 , as claimed in claim 1 , further comprising at least one channel claim 1 , arranged parallel to the longitudinal axis of the housing claim 1 , and configured to transport the water to be purified in an ascending or a descending direction.3. Purification device claim 1 , as claimed in claim 1 , wherein the second purification medium has a substantially round cross section.4. Purification device claim 3 , as claimed in claim 3 , wherein the second purification medium has a substantially circular cross section.5. Purification device claim 1 , as claimed in claim 1 , wherein the second purification medium is a reverse osmosis module.6. Purification device claim 1 , as claimed in claim 1 , wherein the second purification medium is a module claim 1 , a bed claim 1 , a capsule or a cartridge claim 1 , which contains an activated charcoal/ion exchange resin mixture or stack.7. Purification device claim 1 , as ...

Conversion of fructose-containing feedstocks to hmf-containing product

The present invention relates generally to processes for converting fructose-containing feedstocks to a product comprising 5-(hydroxymethyl)furfural (HMF) and water in the presence of water, solvent and an acid catalyst. In some embodiments, the conversion of fructose to HMF is controlled at a partial conversion endpoint characterized by a yield of HMF from fructose that does not exceed about 80 mol %. In these and other embodiments, the processes provide separation techniques for separating and recovering the product, unconverted fructose, solvent and acid catalyst to enable the effective recovery and reutilization of reaction components.

WATER CONDITIONING SYSTEMS HAVING DIVERSION DEVICES

A portable water conditioning system is provided that includes an incoming water inlet; a reverse osmosis stage in fluid communication with the incoming water inlet, the reverse osmosis stage having a permeate outlet and a concentrate outlet; a diversion device having a diversion valve, the diversion valve placing the concentrate outlet in fluid communication with a waste water outlet; a deionizing stage in fluid communication with a pure water outlet; a bypass valve configured to selectively place the permeate outlet in fluid communication with one or more of the waste water outlet, the deionizing stage, and the pure water outlet; and a controller configured to control the diversion device and the bypass valve to provide water at the pure water outlet of a desired condition. 1. A method for conditioning water comprising:receiving incoming water at a water inlet of a water conditioning system;passing the incoming water through a reverse osmosis stage of the water conditioning system, the reverse osmosis stage having a permeate outlet and a concentrate outlet;selectively placing the permeate outlet in fluid communication with each of a waste water outlet, a deionizing stage of the water conditioning system, and a pure water outlet using a bypass valve, wherein the deionizing stage is in fluid communication with the pure water outlet, wherein the selective placement of the permeate outlet is selected based on a desired condition of water to be output from the water conditioning system.2. The method of claim 1 , further comprising starting operation of the water conditioning system by:opening the bypass valve; andincreasing a waste water flow to transfer water having high total dissolved solids to pass through the waste water outlet.3. The method of claim 1 , further comprising shutting down operation of the water conditioning system by:closing the bypass valve to flush the system of waste water; andincreasing a flow of waste water through the concentrate outlet and ...

FLUID PURIFICATION BY FORWARD OSMOSIS, ION EXCHANGE AND RE-CONCENTRATION

An apparatus () for purifying fluid, wherein the apparatus () comprises an osmosis unit () configured for pre-purifying the fluid to be purified by forward osmosis of the fluid, which is to be purified, through an osmosis membrane () into a chamber () comprising dissolved first ions, in particular first cations and first anions, an ion exchange unit () configured for exchanging at least part of the first ions, in particular at least part of at least one of the first cations and the first anions, by second ions, in particular at least one of second cations and second anions, and a re-concentration unit () configured for separating the pre-purified fluid after the ion exchange into purified fluid and into a re-concentrate enriched with the respective ions, in particular anions and cations. 1. An apparatus for purifying fluid , the apparatus comprising:an osmosis unit configured for pre-purifying the fluid to be purified by forward osmosis of the fluid to be purified through an osmosis membrane into a chamber comprising dissolved first ions, in particular first cations and first anions;an ion exchange unit configured for exchanging at least part of the first ions, in particular at least part of at least one of the first cations and the first anions, by second ions, in particular at least one of second cations and second anions;a re-concentration unit configured for separating the pre-purified fluid after the ion exchange into purified fluid and into a re-concentrate enriched with the respective ions, in particular anions and cations.2. The apparatus according to claim 1 , wherein the osmosis unit is configured for promoting a flow of the fluid to be purified through the osmosis membrane while inhibiting a flow of contaminants from the fluid to be purified towards the chamber and while inhibiting the first ions claim 1 , in particular the first cations and the first anions claim 1 , from flowing through the osmosis membrane towards the fluid to be purified.3. The ...

SYSTEMS AND METHODS FOR WATER FILTRATION

A water filtration systems may comprise an under the sink RO water filtration system that is plumed into a building's water supply. For example; the water filtration systems may include an RO device at least partially installed underneath a sink, with the tap water connection plumbed directly to the sink cold water supply line, and a waste water drain line connected directly to the sink drain, such as the p-trap. 1. A reverse osmosis water treatment system , comprising:a source of water;a water tank comprising a first inlet, a second inlet, a first outlet, and a second outlet, wherein the first inlet of the water tank is in fluid communication with the source of water;a filter system comprising an inlet, a first outlet, and a second outlet, wherein the inlet of the filtration system is in fluid communication with the first outlet of the water tank, wherein the first outlet of the filter system is in fluid communication with the second inlet of the water tank, wherein the first outlet of the filter system supplies waste water to the water tank, and wherein the water tank comprises a mixture of water from the source of water and waste water from the filter system;a filtered water tank comprising an inlet and an outlet, wherein the inlet of the filtered water tank is in fluid communication with the second outlet of the filter system, wherein the second outlet of the filter system supplies filtered water to the filtered water tank, wherein the outlet of the filtered water tank is in fluid communication with a faucet; and wherein the outlet of the filtered water tank supplies the filtered water to the faucet;a first pump disposed in fluid communication between the water tank and the filter system; anda second pump disposed in fluid communication between the water tank and a drain, wherein the second outlet of the water tank is in fluid communication with the second pump, and wherein the second pump supplies a portion of the water from the water tank to the drain.2. The ...

SYSTEMS AND METHODS FOR WATER FILTRATION

A water filtration systems may comprise an under the sink RO water filtration system that is plumed into a building's water supply. For example, the water filtration systems may include an RO device at least partially installed underneath a sink, with the tap water connection plumbed directly to the sink cold water supply line, and a waste water drain line connected directly to the sink drain, such as the p-trap. 1. A reverse osmosis water treatment system , comprising:a source of water;a first three-way valve comprising a first inlet, a second inlet, and an outlet, wherein the first inlet of the first three-way valve is in fluid communication with the source of water;a filter system comprising an inlet, a first outlet, and a second outlet, wherein the inlet of the filtration system is in fluid communication with the outlet of the first three-way valve, wherein the first outlet of the filter system is in fluid communication with the second inlet of the first three-way valve, wherein the first outlet of the filter system supplies waste water from the filter system to the first three-way valve, and wherein the first three-way valve mixes water from the source of water and waste water from the filter system;a filtered water tank comprising an inlet and an outlet, wherein the inlet of the filtered water tank is in fluid communication with the second outlet of the filter system, wherein the second outlet of the filter system supplies filtered water to the filtered water tank, wherein the outlet of the filtered water tank is in fluid communication with a faucet, and wherein the outlet of the filtered water tank supplies the filtered water to the faucet;a pump disposed in fluid communication between the first three-way valve and the filter system; anda second three-way valve disposed in fluid communication between the first three-way valve and the filter system and in fluid communication with a drain, wherein the second three-way valve diverts a first portion of water from ...

Methods and systems for treating high temperature produced water

Produced water from a crude oil or natural gas production process is purified using a membrane purification system for petroleum production, agricultural, commercial and domestic uses. The produced water is pretreated to remove, at least, particulates and oil from the produced water. The minimally pretreated water is then purified in a membrane purification system, that is operated at conditions such that membrane scaling is reduced or prevented. In particular, the membrane purification system is operated to maintain the turbidity of clarified water feed to the system or intermediate aqueous streams that are cascading through the membrane purification system. Ensuring that the turbidity of the reject streams generated in the membrane system are useful in achieving long membrane operating life.

SYSTEMS AND METHODS FOR WATER FILTRATION

A water filtration systems may comprise an under the sink RO water filtration system that is plumed into a building's water supply. For example, the water filtration systems may include an RO device at least partially installed underneath a sink, with the tap water connection plumbed directly to the sink cold water supply line, and a waste water drain line connected directly to the sink drain, such as the p-trap. 1. A reverse osmosis water treatment system , comprising:a source of water;a water tank comprising a first inlet, a second inlet, and an outlet, wherein the first inlet of the water tank is in fluid communication with the source of water by way of a first pipe;a filter system comprising an inlet, a first outlet, and a second outlet, wherein the inlet of the filtration system is in fluid communication with the outlet of the water tank by way of a second pipe, wherein the first outlet of the filter system is in fluid communication with the second inlet of the water tank by way of a third pipe, wherein the first outlet of the filter system supplies waste water from the filter system to the water tank, and wherein the water tank comprises a mixture of water from the source of water and waste water from the filter system;a faucet in fluid communication with the second outlet of the filter system, wherein the second outlet of the filter system supplies filtered water to the faucet;a pump disposed in fluid communication along the second pipe between the water tank and the filter system; anda valve disposed in fluid communication along the second pipe between the pump and the filter system and in fluid communication with a drain by way of a fourth pipe, wherein the valve diverts a first portion of water from the water tank to the filter system via the second pipe, and wherein the valve diverts a second portion of water from the water tank to the drain via the fourth pipe.2. The system of claim 1 , wherein the filter system further comprises:a first filter and a ...

Liquid Purification System

A liquid purification system includes a filter system having a set of filters with a feed stream, a concentrate stream, and a permeate stream. The feed stream constitutes an input to the liquid purification system. The liquid purification system also includes an electrodialysis system having at least one stack of at least one pair of electrodes, between which is disposed at least one cell pair having an anion exchange membrane and a cation exchange membrane. The electrodialysis system includes a diluate inlet, a diluate outlet and a concentrate outlet. The diluate inlet is fluidly coupled to the concentrate stream and at least a portion of the diluate outlet is fluidly coupled to at least a portion of the permeate stream to produce a purified output stream. A ratio of electrical conductivity of the purified output stream to the feed stream is no less than about 0.55. 1. A liquid purification system comprising:a filter system having a set of filters with a feed stream, a concentrate stream, and a permeate stream, wherein the feed stream constitutes an input to the liquid purification system; andan electrodialysis system having at least one stack of at least one pair of electrodes, between which is disposed at least one cell pair having an anion exchange membrane and a cation exchange membrane, the electrodialysis system having a diluate inlet, a diluate outlet and a concentrate outlet, wherein the diluate inlet is fluidly coupled to the concentrate stream and at least a portion of the diluate outlet is fluidly coupled to at least a portion of the permeate stream to produce a purified output stream,wherein a ratio of electrical conductivity of the purified output stream to the feed stream is no less than about 0.55.2. The liquid purification system according to claim 1 , wherein a ratio of electrical conductivity of the concentrate stream to the electrical conductivity of the feed stream is no greater than a factor of 2.3. The liquid purification system according to ...

PROCESS FOR THE PURIFICATION OF RECOMBINANT PROTEINS

A process for the extraction and purification of recombinant proteins, more specifically interferons and insulin, having improved quality and yield. The process comprises extraction of proteins from bacterial inclusion bodies using an extraction solution comprising at least one detergent; at least one chaotropic agent; at least one cosmotropic agent; and a protein folding agent. 1. An extraction solution for recovery of proteins from bacterial inclusion bodies , comprising:at least one detergent;at least one chaotropic agent;at least one cosmotropic agent; anda protein folding agent;wherein said extraction solution has a pH of between about 1.5 and about 12.2. The extraction solution of claim 1 , wherein said extraction solution has a pH of between about 7.2 and about 8.5.3. The extraction solution of claim 1 , wherein said chaotropic agent is selected from the group consisting of urea claim 1 , guanidinium chloride claim 1 , thiourea claim 1 , and mixtures thereof.4. The extraction solution of claim 1 , wherein said cosmotropic agent is selected from the group consisting of chloride salts claim 1 , sulfate salts claim 1 , and mixtures thereof.5. The extraction solution of claim 1 , wherein said cosmotropic agent is selected from the group consisting of sodium chloride claim 1 , potassium chloride claim 1 , ammonium sulfate claim 1 , and mixtures thereof.6. The extraction solution of claim 1 , wherein said protein folding agent is arginine.7. A kit for recovery of proteins from bacterial inclusion bodies claim 1 , comprising:an extraction solution for dissolving said proteins, comprising at least one detergent; at least one chaotropic agent; at least one cosmotropic agent; and arginine; andan oxidizing agent for oxidizing said dissolved proteins;wherein said extraction solution has a pH of between about 7.2 and about 8.5; andwherein said oxidizing agent is a thiol, a disulfide, or a mixture thereof.8. A process for recovery of a protein from bacterial inclusion ...

Device for removing microparticles contained in water and ultrapure-water prouction and supply system

In a subsystem or water-feed path located upsteam of a use point in an ultrapure water production/supply process, fine particles having a particle diameter of 50 nm or less, in particular 10 nm or less are highly removed. A device for removing fine particles in water has a membrane filtration device including a microfiltration membrane or an ultrafiltration membrane having a weak cationic functional group. The microfiltration membrane or the ultrafiltration membrane having a weak cationic functional group is preferred to have a polyketone film with the weak cationic functional group. Negatively-charged particles in water are adsorbed by the weak cationic functional group and can thus be removed.

Process of producing 1,4-butanediol

A process produces 1,4-butanediol by purifying 1,4-butanediol originated from a fermentation broth, by which process 1,4-butanediol having properties suited as a material of producing a polyester is obtained, which 1,4-butanediol enables to reduce by-production of tetrahydrofuran during the esterification reaction and to reduce the delay in polymerization. The process of producing 1,4-butanediol includes adding an alkaline substance other than an ammonia or an amine to an aqueous 1,4-butanediol-containing solution originated from a fermentation broth; distilling the resulting mixture; and recovering a 1,4-butanediol-containing solution from the vapor flow.

A Manufacturing Facility for the Production of Biopharmaceuticals

A manufacturing facility for the continuous production of biopharmaceuticals integrated with single-use disposable technology. 1. A manufacturing system for biopharmaceuticals comprising:at least one inputting device connected to at least one inoculum expansion device through at least one piece of tubing and a connector;said at least one inoculum expansion device is connected to at least one production stage bioreactor device through at least one piece of tubing and a connector;said at least one production stage bioreactor device is connected to at least one primary recovery device through at least one piece of tubing and a connector,said at least one primary recovery device is connected to at least one capturing device through at least one piece of tubing and a connector;said at least one capturing device is connected to at least one ultrafiltration and diafiltration device through at least one piece of tubing and a connector,said at least one ultrafiltration and diafiltration device is connected to at least one polishing membranes device through at least one piece of tubing and a connector,said at least one polishing membranes device is connected to at least one polishing using cation exchange device through at least one piece of tubing and a connector;said at least one polishing using cation exchange device is connected to at least one virus reduction filtration device through at least one piece of tubing and a connector; andsaid at least one virus reduction filtration device is connected to at least one ultrafiltration and diafiltration device through at least one piece of tubing and a connector;said at least one ultrafiltration and diafiltration device is connected to at least one automated bulk fill device through at least one piece of tubing and a connector.2. The manufacturing system of claim 1 , wherein the device can be from at least two different manufacturers.3. The manufacturing system of claim 1 , wherein at least one device is not made for single-use. ...

CONTAINER FOR A FILTER CARTRIDGE AND FILTER SET

The disclosure relates to a container for a filter cartridge, and a filter set which comprises such a container. The container has a bottom with a drain line connecting a cavity for accommodating the filter cartridge with the outer side of the container, and a side wall. The bottom and the side wall form the cavity. The filter cartridge is filled with a filter material. In order to enable utilisation of both ion exchanger filter cartridges and reverse osmosis filter cartridges, the drain line includes an extension that can receive a throttle valve, e.g. an apertured diaphragm, when using a reverse osmosis filter cartridge and, in addition, includes a ball valve that is closed when the inserted filter cartridge is an ion exchanger filter cartridge, and open otherwise. 1. A container for a filter cartridge , the container comprising:a bottom; and an outlet opening in the cavity,', 'a drain opening on an outer side of the container, and', 'a drain line passing through the bottom, the drain line connects the outlet opening with the drain opening and includes a socket for receiving a throttle valve and further includes a stop valve., 'a circumferential side wall connected to the bottom, the container forming a cavity for the filter cartridge that is open on an upper side opposite the bottom, and wherein the bottom includes2. The container according to claim 1 , wherein the upper side of the bottom facing the cavity comprises a circumferential edge area adjoining the side wall claim 1 , and a central depression surrounded by the edge area claim 1 , and wherein the outlet opening is situated in the central depression.3. The container according to claim 2 , wherein the bottom includes a sealing ring arranged in a circumferential groove in the edge area.4. The container according to claim 1 , wherein the socket is arranged between the cavity and the stop valve.5. The container according to claim 4 , wherein the socket is arranged near the outlet opening in such a way that ...

PURIFICATION PLATFORMS FOR OBTAINING PHARMACEUTICAL COMPOSITIONS HAVING A REDUCED HYDROLYTIC ENZYME ACTIVITY RATE

The present disclosure provides purification platforms comprising a depth filter step and/or a hydrophobic interaction chromatography (HIC) step and/or a MM-HIC/IEX chromatography step, and are useful for providing a method of reducing a hydrolytic enzyme activity rate of a composition obtained from said purification platforms. Also disclosed herein are methods of using the purification platforms described herein and compositions obtained therefrom, such as pharmaceutical compositions.

METHOD OF SEPARATING LACTIC ACID OR SALT THEREOF

Provided is a method of separating lactic acid or a salt thereof. The method includes removing a coloring material, including hydroxymethylfurfural (HMF), from a fermentation broth, which includes at least one of lactic acid and a salt thereof; and recovering lactic acid or a salt thereof from the fermentation broth, from which the coloring material has been removed. 1. A method of separating a lactic acid or a salt thereof , the method comprising:removing a coloring material comprising hydroxymethylfurfural (HMF) from a fermentation broth, wherein the fermentation broth comprises lactic acid or a salt thereof; andrecovering the lactic acid or a salt thereof from the fermentation broth after the coloring material has been removed.2. The method of claim 1 , wherein removing of the coloring material comprises filtering the fermentation broth.3. The method of claim 2 , wherein filtering of the fermentation broth comprises passing the fermentation broth through a nano-filtration membrane.4. The method of claim 3 , wherein the nano-filtration membrane has a molecular weight cutoff (MWCO) of about 100 Daltons to about 800 Daltons.5. The method of claim 2 , wherein filtering the fermentation broth comprises passing the fermentation broth through a filter after adding a material that adsorbs the coloring material to the fermentation broth so as to batch-adsorb the coloring material.6. The method of claim 5 , wherein the material that adsorbs the coloring material comprises activated carbon claim 5 , a styrene polymer claim 5 , a cross-linked polystyrene co-polymer claim 5 , or combination thereof.7. The method of claim 6 , wherein the material that adsorbs the coloring material comprises activated carbon with an average pore diameter of about 2.3 nm to about 3.5 nm as measured by Brunauer-Emmett-Teller (BET) analysis.8. The method of claim 6 , wherein the material that adsorbs the coloring material comprises activated carbon with a pore volume measured by using a Barett- ...

Process for Purification of an Organic Acid Including an Electrodialysis Treatment Step

It is an object of the invention to provide a process for producing an organic acid, comprising: providing an incoming stream containing an organic acid and impurities; subjecting said incoming stream to a step of chromatographic separation, using a solution of mineral acid as an eluent, so as to collect an extract and a raffinate, the organic acid being recovered in the extract; and subjecting the raffinate to an electrodialysis step, so as to collect a diluate and a concentrate, the mineral acid being concentrated in the concentrate. The invention also provides an installation for implementing this process. 1. A process for producing an organic acid , comprising:providing an incoming stream containing an organic acid and impurities;subjecting said incoming stream to a step of chromatographic separation, using a solution of mineral acid as an eluent, so as to collect an extract and a raffinate, the organic acid being recovered in the extract; andsubjecting the raffinate to an electrodialysis step, so as to collect a diluate and a concentrate, the mineral acid being concentrated in the concentrate.2. The process of claim 1 , wherein the solution of mineral acid is selected from a solution of sulfuric acid claim 1 , phosphoric acid claim 1 , nitric acid claim 1 , hydrochloric acid and combinations thereof.3. The process of claim 1 , wherein the organic acid comprises citric acid.4. The process of claim 1 , wherein the eluent contains less than 20 g/L.5. The process of claim 1 , wherein the diluate is subjected to a concentration step so as to collect a diluted fraction on the one hand and a concentrated fraction on the other hand.6. The process of claim 1 , wherein at least part of the concentrate claim 1 , and preferably all of the concentrate claim 1 , is recycled with the incoming stream.7. The process of claim 1 , wherein at least part of the concentrate is recycled with the eluent in the step of chromatographic separation.8. The process of claim 1 , wherein ...

METHOD FOR CONCENTRATING AND PURIFYING ELUATE BRINE FOR THE PRODUCTION OF A PURIFIED LITHIUM COMPOUND

A method is disclosed for concentrating and purifying an eluate brine and producing a purified lithium compound. An extraction eluate, rich in lithium, is directed to a nanofiltration unit or a softening process that removes sulfate and/or calcium and magnesium. Permeate from the nanofiltration unit or the effluent from the softening process is directed through an electrodialysis unit. As the lithium-rich solution moves through the electrodialysis unit, lithium, sodium and chloride ions pass from the solution through a cation-transfer membrane and an anion-transfer membrane to concentrate compartments. A dilute stream is directed through the concentrate compartments and collects the lithium, sodium and chloride ions. The electrodialysis unit also produces a product stream which contains non-ionized impurities, such as silica and/or boron. Concentrate from the electrodialysis unit is subject to a precipitation process that produces a lithium compound that is subsequently subjected to a purification process. 1. A method of recovering lithium carbonate from a brine rich in lithium , sodium and chloride and having impurities in the form of hardness , sulfate , and silica , the method comprising:directing the brine to a nanofiltration unit and subjecting the brine to nanofiltration and removing sulfate from the brine, along with hardness associated with the sulfate;wherein after nanofiltration, the brine still contains silica and residual hardness and remains rich in lithium, sodium and chloride;after nanofiltration, maintaining conditions in the brine that result in the silica being substantially non-ionized;further after nanofiltration, directing the brine through an electrodialysis unit and subjecting the brine to an electrodialysis process and producing a concentrate rich in lithium, sodium and chloride and a product stream depleted in lithium, sodium and chloride but including the substantially non-ionized silica;after subjecting the brine to the electrodialysis ...

REMOVAL OF CONTAMINATING VIRUSES FROM AAV PREPARATIONS

The present invention relates to a separation of viruses of an essentially spherical shape from viruses with a rod-like shape that are comprised in a sample, wherein the sample comprising the viruses is subjected to filtration. 1. A method of subjecting a sample containing parvoviral virions to a contaminating virus removal step , the method comprising filtering the sample through a filter that has a pore size of 30-40 nm , thereby removing contaminating viruses from the sample , if present , and eluting the parvoviral virions; wherein the contaminating viruses have a rod-like shape.2. The method according to claim 1 , wherein the contaminating virus is a baculovirus.3. The method according to further comprising one or more steps selected from the group consisting of a lysis step claim 1 , a density gradient step claim 1 , a pre-filtration step claim 1 , a chromatography step claim 1 , an affinity chromatography step claim 1 , and an ion-exchange chromatography step.4. The method according to claim 3 , wherein the lysis step comprises freeze-thawing claim 3 , enzymatic hydrolysis claim 3 , and/or detergent lysis.5. The method according to claim 3 , wherein the pre-filtration step comprises filtering the sample through a filter that has a pore size of 70-200 nm.6. The method according to claim 1 , wherein the parvoviral virons are adeno-associated virus (AAV) virons.7. The method according to claim 1 , wherein at least 90% of the parvoviral virons in the sample are recovered in the filtrate.8. The method according to claim 1 , wherein the amount of contaminating virus in the filtrate is reduced by at least 5 logs relative to the sample before filtering.9. The method according to claim 1 , wherein contaminating virus has an aspect ratio of at least 4:1.10Autographa californica. The method according to claim 2 , wherein baculovirus is multicapsid nucleopolyhedrovirus.11. A method for ensuring the purity of a parvoviral product claim 2 , comprising (a) obtaining a ...

DIAGNOSTIC METHODS AND APPARATUS FOR ELECTRODIALYSIS

The present disclosure is directed to ion-exchange systems and devices that can monitor key parameters related to the performance of the ion-exchange device. Specifically, the ion-exchange systems and devices disclosed herein can provide real time voltage drop across groups of membrane pairs using diagnostic spacer borders between the pairs. In addition, the ion-exchange systems and devices disclosed herein can monitor the compression force applied by the compression plates holding the ion-exchange systems and devices together. 1. A diagnostic spacer border for an ion exchange device comprising:a groove in a surface of the spacer border;an electrode, wherein at least a portion of the electrode is in the groove; anda wire lead connected to the electrode.2. The spacer border of claim 1 , further comprising an internal cavity claim 1 , wherein a portion of the electrode protrudes from the groove into the internal cavity.3. The spacer border of claim 1 , wherein the wire lead and the electrode are connected by a solder joint.4. The spacer border of claim 1 , wherein the groove comprises a cured polymer solution.5. The spacer border of claim 2 , further comprising a tab protruding from a perimeter of the spacer border away from the internal cavity.6. The spacer border of claim 5 , wherein the wire lead is connected to the electrode on the tab.7. The spacer border of claim 5 , wherein the tab is coated with a graphitic mixture.8. The spacer border of claim 1 , wherein the electrode is a wire electrode.9. The spacer border of claim 8 , wherein the wire electrode comprises titanium claim 8 , platinum claim 8 , or gold.10. The spacer border of claim 1 , wherein the electrode is a graphite electrode.11. The spacer border of claim 1 , wherein the electrode comprises a graphite electrode and a wire electrode.12. A method of making a diagnostic spacer border for an ion exchange device comprising:etching a groove into a surface of a spacer border having an internal cavity; ...

SEPARATION OF OLIGOSACCHARIDES FROM FERMENTATION BROTH

The invention relates to a method for obtaining an N-acetylglucosamine containing neutral oligosaccharide from a fermentation broth, wherein said oligosaccharide is produced by culturing a genetically modified microorganism capable of producing said oligosaccharide from an internalized carbohydrate precursor, comprising the steps of: i) ultrafiltration (UF), preferably to separate biomass from the broth, ii) nanofiltration (NF), preferably to concentrate said oligosaccharide in the broth and/or reduce an inorganic salt content of the broth, and iii) treating the broth with an ion exchange resin, preferably to remove charged materials, and/or subjecting the broth to chromatography, preferably to remove hydrophobic impurities. 1. A method for separating an N-acetylglucosamine containing neutral oligosaccharide from dissolved inorganic and organic salts , acids and bases in an aqueous medium from a fermentation or enzymatic process , comprising the step of treating said aqueous medium with a strong cation exchange resin in H-form and a weak anion exchange resin in free base form.2. The method according to claim 1 , wherein the treatment with a strong cation exchange resin in H-form is directly followed by a treatment with a weak anion exchange resin in free base form.3. The method according to which does not comprise electrodialysis.4. The method according to claim 1 , which further comprises ultrafiltration and nanofiltration claim 1 , wherein the treatment with a strong cation exchange resin in H-form and a weak anion exchange resin in free base form is preceded by ultrafiltration followed by nanofiltration.5. (canceled)6. A method for separating an N-acetylglucosamine containing neutral oligosaccharide from a fermentation broth obtained by culturing a genetically modified microorganism capable of producing said N-acetylglucosamine containing neutral oligosaccharide from an internalized carbohydrate precursor claim 1 , wherein the separation comprises the steps of:i) ...

Method for extracting epsilon-polylysine and its hydrochloride salt from fermentation broth

The present invention provides a method for extracting ε-polylysine (ε-PL) and its hydrochloride salt from fermentation broth, which belongs to the field of bio-separation engineering. ε-PL and its hydrochloride salt are produced from fermentation broth through sequential solid-liquid separation, ultrafiltration, two-stage ion exchange, nanofiltration, evaporation concentration and drying techniques. Technologies of membrane filtration and two-stage ion exchange are applied to the preparation of ε-PL and its hydrochloride salt in the present invention, and the invention are characterized by reduced cost, improved automation, and increased product yield and purity, and the method of the present invention would be more suitable for industrial production. 1. A method for efficient extraction of ε-polylysine (ε-PL) and its hydrochloride salt from a fermentation broth , comprising the following steps:(1) solid-liquid separating of the fermentation broth: after flocculation or dilution, filtrating or centrifugating the fermentation broth to remove mycelia and water-insoluble impurities, and obtaining a clear fermentation broth supernatant;(2) ultrafiltrating: using an ultrafiltration membrane system to remove the water-soluble macromolecular impurities and water-insoluble impurities in the fermentation broth supernatant, and collecting ultrafiltration permeate;(3) ion-exchanging: pressuring the ultrafiltration permeate into a primary ion exchange column for adsorption until resin is saturated; using a detergent to remove impurities, and using an elution reagent to desorb; collecting eluents from the primary ion exchange column, and then forcing into a secondary ion exchange column, and collecting a final effluent liquid;(4) nanofiltrating: using a nanofiltration membrane system to desalt and concentrate the final effluent liquid obtained from the step (3), and collecting a nanofiltration concentrate;(5) bleaching: decolorating collected nanofiltration concentrate to ...

Process for Purifying Monoclocal Antibodies

A process for purifying a liquid feedstock comprising a monoclonal antibody and impurities, the process comprising passing the liquid feedstock through an apparatus comprising at least two processing units, each such unit producing a product stream containing purified monoclonal antibody and optionally a waste stream comprising at least some of the impurities, wherein each unit comprises specified components (i) to (v) which include a multiple inlet flow-controller comprising two or more variable flow inlet valves for in situ production of a bioprocessing liquid by combining at least two liquids in a desired ratio. One of the units performs chromatography and another performs viral inactivation. The units may be essentially the same except for a device they contain, leading to advantages in terms of simplicity, cost and ease of operation, lower risk of operator error, easier maintenance and lower inventory of spare parts.

WATER CONDITIONING SYSTEMS

A portable water conditioning system is provided that includes a water conditioner, a first sensor, a second sensor, and a controller. The water conditioner has a plurality of conditioning stages that condition water. The plurality of conditioning stages include, in a direction of flow of the water through the water conditioner, a reverse osmosis stage and a deionizing stage. The first sensor detects a first condition of the water before the reverse osmosis stage. The second sensor detects a second condition of the water after the reverse osmosis stage. The controller is in communication with the first and second sensors and determines a health status of the reverse osmosis stage based the first and second conditions. The first and second conditions each include a level of total dissolved solids of the water. 1. A portable water conditioning system , comprising:a water conditioner having a plurality of conditioning stages configured to condition water, the plurality of conditioning stages comprising, in a direction of flow of the water through the water conditioner, a reverse osmosis stage and a deionizing stage;a first sensor configured to detect a first condition of the water before the reverse osmosis stage;a second sensor configured to detect a second condition of the water after the reverse osmosis stage, wherein the first and second conditions each comprise a level of total dissolved solids of the water; anda controller in communication with the first and second sensors, the controller being configured to determine a percent rejection of the reverse osmosis stage based the first and second conditions when at least one variable effecting an accuracy of the determination of the percent rejection is at a known state.2. The system of claim 1 , wherein the at least one variable is pressure on the reverse osmosis stage.3. The system of claim 2 , further comprising a diversion device configured to maintain the pressure at the known state.4. The system of claim 1 , ...

Water conditioning systems

Portable water conditioning systems include a water conditioner having a plurality of conditioning stages including, in a direction of flow of the water through the water conditioner, a reverse osmosis stage having a reverse osmosis membrane, and a deionizing stage. A first sensor is configured to detect a first condition of the water before the reverse osmosis stage and a second sensor configured to detect a second condition of the water after the reverse osmosis stage. The conditions each include (i) a level of total dissolved solids of the water and (ii) temperature of the water. A controller is in communication with the sensors and configured to determine of a percent of dissolved solids that are rejected by the reverse osmosis membrane based on the conditions when backpressure on the reverse osmosis stage is at a known state.

Osmotic separation systems and methods

Separation processes using osmotically driven membrane systems are disclosed generally involving the extraction of solvent from a first solution to concentrate solute by using a second concentrated solution to draw the solvent from the first solution across a semi-permeable membrane.

Spray-dried 3-fucosyllactose

Disclosed is a method for the manufacture of a spray-dried powder consisting essentially of 3-fucosyllactose, the spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions containing the spray-dried powder.

METHOD FOR DETECTING ALBUMIN BASED ON COLORIMETRIC ASSAY AND SYSTEM THEREOF

A method for detecting albumin based on a colorimetric assay and a system thereof are disclosed. Gold nanoparticles are added into the sample preparing device having a sample without spectroscopic tags, wherein the sample without spectroscopic tags is formed as the alkaline solution to avoid the interference substances adhering on the gold nanoparticles. The gold nanoparticles are concentrated by using the microfluidic concentrator with the circular ion exchange membrane by applying an external electric field across two electrodes. The image of the concentrated gold nanoparticles is captured by the image capturing device for measuring the saturation intensities of the image, wherein there is a relation between the saturation intensities and the concentration of the albumin in the sample without spectroscopic tags. The concentration of the albumin of the sample without spectroscopic tags is obtained by the relation and the measured saturation intensities. 1. A method for detecting albumin based on a colorimetric assay , comprising:adding gold nanoparticles into a sample preparing device having a sample without spectroscopic tags, preparing the sample without spectroscopic tags to form an alkaline solution to avoid interference substances adhering on the gold nanoparticles;concentrating the gold nanoparticles by using a microfluidic concentrator with a circular ion exchange membrane and by applying an external electric field across two electrodes;capturing an image of the concentrated gold nanoparticles by an image capturing device for measuring saturation intensities of the image, wherein there is a relation between the saturation intensities and a concentration of the albumin in the sample without spectroscopic tags; andobtaining the concentration of the albumin of the sample without spectroscopic tags by using the relation and the measured saturation intensities.2. The method for detecting albumin based on the colorimetric assay of claim 1 , wherein the saturation ...

Ultrapure water production system, ultrapure water production feed system, and method for cleaning thereof

Contaminants present inside an ultrapure water production system are prevented from being fed into a feed pipe connected to a water use point and, after sterilization cleaning, the system is prevented from being contaminated by contaminants captured on a microparticle removal membrane during sterilization cleaning. Ultrapure water having high quality is thereby fed to a water use point within a short period of time. An ultrapure water production system is provided with a tank, a pump, a heat exchanger, an ultraviolet device, an ion-exchange device, a first microparticle removal membrane device, and a second microparticle removal membrane device. Parts of sterilization water and flush water are fed into the first microparticle removal membrane device and discharged from a feedwater-side potion to a concentrated-water-side portion without permeating through a microparticle removal membrane thereof, and the remaining part of the water is passed through the second microparticle removal membrane device.

SYSTEMS AND METHODS FOR PURIFYING SOLVENTS

The present disclosure is directed to methods of purifying solvents. The purified solvents can be used for cleaning a semiconductor substrate in a multistep semiconductor manufacturing process. 1. A method of purifying an organic solvent , comprising:passing an organic solvent through a first filter to a packaging station in a purification system to obtain a purified organic solvent, the first filter comprising a filter housing and at least one filtration medium within the filter housing, and the at least one filtration medium having an average pore size of at most about 5 nm;wherein the purification system comprises the first filter, the packaging station, and a conduit in fluid communication with the first filter and the packaging station, and the inner surface of the conduit or the filter housing comprises a fluoropolymer.2. The method of claim 1 , further comprising passing the organic solvent through a second filter in fluid communication with and between the first filter and packaging station claim 1 , wherein the second filter comprises a filter housing and at least one filtration medium within the filter housing claim 1 , and the at least one filtration medium in the second filter has an average pore size of at most about 5 nm.3. The method of claim 2 , wherein the at least one filtration medium in the first or second filter comprises a polyamide claim 2 , a polyolefin claim 2 , a fluoropolymer claim 2 , or a copolymer thereof.4. The method of claim 2 , wherein the at least one filtration medium in the first or second filter comprises a nylon claim 2 , a polyethylene claim 2 , a polytetrafluoroethylene claim 2 , or a copolymer thereof.5. The method of claim 2 , wherein the at least one filtration medium in the first filter comprises a nylon.6. The method of claim 2 , wherein the at least one filtration medium in the second filter comprises a polytetrafluoroethylene.7. The method of claim 2 , wherein the inner surface of the filter housing of the second ...

Membrane-based processing for ambient water-group species captured on the Moon and in space

According to the method and device for a membrane-based processing of ambient water-group species, the species are captured in a space environment by an ionic liquid disposed on a presenting face of a semipermeable membrane. To seamlessly process the captured species for in-situ resource utilization without need of moving parts, they are urged to pass through the membrane by a predetermined electric potential difference applied between opposite sides of the membrane via electrode contacts; an initial storage envelope is provided by an impermeable membrane attached to a back face of the semipermeable membrane. The device can be stowed in a manner of rolled plastic and deployed by unrolling. The device can also be configured as a scientific instrument to monitor a flux of ambient water-group species impinging in the space environment using electrical measurements.

ION PROCESSING DEVICE, ION CHROMATOGRAPH PROVIDED WITH THE ION PROCESSING DEVICE, AND ELUENT GENERATOR PROVIDED WITH THE ION PROCESSING DEVICE

An ion processing device includes, on the side of an anion exchange layer of a bipolar membrane which is formed by stacking an anion exchange layer and a cation exchange layer, an anion-side channel which is filled with an anion exchanger, and an anion removal channel provided via an anion exchange membrane, and also includes an anode for moving anions from the anion-side channel to the anion removal channel through the anion exchange membrane. Further, a cation-side channel which is filled with a cation exchanger and a cation removal channel provided via a cation exchange membrane are included on the side of the cation exchange layer of the bipolar membrane as well as a cathode for moving cations from the cation-side channel to the cation removal channel through the cation exchange membrane. 1. An ion processing device comprising:a bipolar membrane that is formed by stacking an anion exchange layer and a cation exchange layer;an anion-side channel that is arranged in contact with the anion exchange layer of the bipolar membrane, and that is filled with an anion exchanger;an anion removal channel that is arranged in contact with the anion-side channel via an anion exchange membrane;an anode for moving anions from the anion-side channel to the anion removal channel through the anion exchange membrane;a cation-side channel that is arranged in contact with the cation exchange layer of the bipolar membrane, and that is filled with a cation exchanger;a cation removal channel that is arranged in contact with the cation-side channel via a cation exchange membrane; anda cathode for moving cations from the cation-side channel to the cation removal channel through the cation exchange membrane.2. The ion processing device according to claim 1 , further comprising a channel branching section for dividing and introducing a liquid from one channel into the anion-side channel and the cation-side channel.3. An ion chromatograph comprising:a separation column for separating a sample ...

A Method Of Producing Lactic Acid

A process for producing pure lactic acid from a whey by-product rich in lactose and minerals, for example delactosed why permeate or concentrated whey permeate, is described. The method comprises upstream steps of neutralising the whey by-product with a basic metal hydroxide to form a precipitate comprising calcium and phosphate, and separating the precipitate from the whey by-product to provide a clarified whey by-product. The clarified whey by-product is fermentated by a bacterium capable of bioconversion of lactose to lactic acid to provide a fermentation broth containing a lactic acid salt. In the downstream steps, the fermentation broth is acidified to release lactic acid from the lactic acid salt, precipitate from the broth produced by acidification is removed, and the acidified fermentation broth is treated to recover pure lactic acid by removal of residual salts, and water, and optionally protein. The process of the invention produces lactic acid having a purity of 80-98% and an isomeric purity of >98% L-lactic acid using a process that employs upstream removal of divalent salts by chemical precipitation, bacterial fermentation of the demineralised substrate, and minimum downstream processing of the fermentation broth. The methods of the invention may also be employed with milk permeates. 1. A process for producing pure lactic acid from a liquid whey by-product that contains at least 30 g/L lactose and at least 1500 ppm chloride , the method comprising the steps of:neutralising the whey by-product with a basic metal hydroxide to form a precipitate comprising calcium and phosphate;separating the precipitate from the whey by-product to provide a clarified whey by-product;incubating the clarified whey by-product with a bacterium capable of bioconversion of lactose to lactic acid to provide a fermentation broth containing lactic acid in the form of a lactic acid salt;acidification of the fermentation broth to release lactic acid from the lactic acid salt; ...

Apparatus and methods for fractionation of biological products

Methods and apparatus for purification of biological molecules using combinations of tangential flow filtration subunits and adsorption sub-units in a single apparatus where the subunits may be operated independently or in series and where the apparatus and methods are suitable for use in a wide range of formats distinct from conditions required for chromatographic processes such as conducting process steps using adsorption subunits for purification of a biological molecule in a contaminated sample without prior buffer equilibration.

CHEMICAL LIQUID PURIFICATION METHOD

An object of the present invention is to provide a chemical liquid purification method which makes it possible to obtain a chemical liquid having excellent defect inhibition performance. The chemical liquid purification method according to an embodiment of the present invention is a chemical liquid purification method including obtaining a chemical liquid by filtering a substance to be purified containing an organic solvent by using two or more kinds of filters having different pore sizes, in which a supply pressure Pof the substance to be purified supplied to a filter Fhaving a maximum pore size Xamong the two or more kinds of filters and a supply pressure Pof the substance to be purified supplied to a filter Fhaving a minimum pore size Xamong the two or more kinds of filters satisfy P>P. 1. A chemical liquid purification method comprising:obtaining a chemical liquid by filtering a substance to be purified containing an organic solvent by using two or more kinds of filters having different pore sizes,{'sub': 1', 'max', '1', '2', 'min', '2', '1', '2, 'wherein a supply pressure Pof the substance to be purified supplied to a filter Fhaving a maximum pore size Xamong the two or more kinds of filters and a supply pressure Pof the substance to be purified supplied to a filter Fhaving a minimum pore size Xamong the two or more kinds of filters satisfy P>P.'}2. The chemical liquid purification method according to claim 1 ,wherein a size relationship among the pore sizes of the two or more kinds of filters coincides with a magnitude relationship among the supply pressures of the substance to be purified supplied to each of the two or more kinds of filters.3. The chemical liquid purification method according to claim 1 ,{'sub': 1', '2, 'wherein the pore size Xis 110% to 20,000% of the pore size X.'}4. The chemical liquid purification method according to claim 1 ,{'sub': '2', 'wherein the pore size Xis 1.0 to 15 nm.'}5. The chemical liquid purification method according to ...

ULTRAPURE-WATER PRODUCTION SYSTEM

The ultrapure-water production system includes an auxiliary treatment apparatus and a dead-end filtration apparatus. The auxiliary treatment apparatus treats water such that the number of microparticles present in water treated by the auxiliary treatment apparatus is 800 to 1200 particles/mL. The dead-end filtration apparatus includes a filtration membrane that is a microfiltration membrane having pores formed in the surface of the membrane at an opening ratio of 50% to 90% with a size of 0.05 to 1 μm, and having a thickness of 0.1 to 1 mm, or an ultrafiltration membrane having pores formed in the surface of the membrane with a size of 0.005 to 0.05 μm, the number of the pores being 1E13 to 1E15 pores/m, the ultrafiltration membrane having a thickness of 0.1 to 1 mm and a transmembrane pressure of 0.02 to 0.10 MPa at a permeation flux of 10 m/m/d. 1. An ultrapure-water production system comprising an auxiliary treatment apparatus and a dead-end filtration apparatus that treats water treated by the auxiliary treatment apparatus ,the auxiliary treatment apparatus treating water such that the number of microparticles present in water treated by the auxiliary treatment apparatus is 800 to 1200 particles/mL (particle size: 20 nm or more), the number of microparticles being measured by a 60-minute moving average method with an online particle monitor Ultra-DI20 produced by Particle Measuring Systems capable of measuring microparticles having a size of 20 nm with a detection sensitivity of 5% and a measurement error of ±20%, the online particle monitor receiving the water treated by the auxiliary treatment apparatus through a sampling cock disposed on a main pipe,{'sup': 2', '3', '2, 'the dead-end filtration apparatus including a filtration membrane, the filtration membrane being a microfiltration membrane having pores with a size of 0.05 to 1 μm, the pores being formed in the surface of the membrane at an opening ratio of 50% to 90%, the microfiltration membrane having a ...

Systems and Methods for Purifying Solvents

The present disclosure is directed to methods and systems of purifying solvents. The purified solvents can be used for cleaning a semiconductor substrate in a multistep semiconductor manufacturing process. 1. A method for removing metal impurities from an organic solvent , comprising:passing the organic solvent through first and second filter units to obtain a purified organic solvent,wherein the first filter unit comprises a first housing and at least one first filter in the first housing, and the first filter comprises a filtration medium comprising a positively charged ion exchange resin; andwherein the second filter unit comprises a second housing and at least one second filter in the second housing, and the second filter comprises a filtration medium comprising a negatively charged ion exchange resin.2. The method of claim 1 , wherein the filtration medium in the first or second filter comprises a polyamide claim 1 , a polyolefin claim 1 , a fluoropolymer claim 1 , or a copolymer thereof.3. The method of claim 1 , wherein the filtration medium in the first filter comprises a polyamide.4. The method of claim 3 , wherein the filtration medium in the first filter comprises a nylon.5. The method of claim 1 , wherein the filtration medium in the first filter comprises quaternary ammonium groups.6. The method of claim 1 , wherein the filtration medium in the second filter comprises high density polyethylene.7. The method of claim 1 , wherein the filtration medium in the second filter comprises sulfonate groups.8. The method of claim 1 , wherein the filtration medium in the first or second filter comprises a polytetrafluoroethylene.9. The method of claim 1 , wherein the first filter unit comprises 1 to 20 first filters claim 1 , and the second filter unit comprises 1 to 20 second filters.10. The method of claim 1 , wherein passing the organic solvent through the first or second filter unit is performed at a temperature of at most about 80° F.11. The method of claim 1 ...

A Method For Producing Ultrapure Water

The present invention relates to a method for producing purified water comprising a step of passing water through an ultrafiltration means and a mixed bed ion exchanger comprising comprising beads having a pore size of 20-100 nm, wherein the ultrafiltration means is located upstream of said mixed bed ion exchanger, as well as to a module comprising an ultrafiltration means and a mixed bed ion exchanger and a water treatment system for producing ultrapure water comprising ultrafiltration means and a mixed bed ion exchanger.

PRODUCTION OF OLIGOSACCHARIDES

A method for producing and purifying human milk oligosaccharides (HMOs) is provided. The method includes fermentation of a genetically modified microbial organism, preferably a genetically modified yeast strain, and downstream processing of the fermentation product using one or more of an enzymatic treatment, filtration, and a simulated moving bed (SMB) chromatography step. Use of the resulting HMO in food or feed applications, preferably in infant food and/or formula is also provided. 1. A method for the production of one or more human milk oligosaccharides (HMOs) comprising:a) fermentation of a microbial organism that has been genetically modified to produce one or more HMOs in a suitable fermentation medium to form a fermentation product;b) enzymatic treatment of the fermentation product;c) removal of the biomass from the fermentation product;d) ultrafiltration;e) nanofiltration; andf) a column chromatography step.2. The method of claim 1 , wherein the one or more HMOs is 2′-fucosyllactose.3. The method of or claim 1 , wherein the microbial organism is a yeast.4Saccharomyces, Candida, Hansenula, Kluyveromyces, Pichia, Schizosaccharomyces, Schwanniomyces, Torulaspora, Yarrowia,Zygosaccharomyces.. The method of claim 3 , wherein the yeast is selected from the group consisting of: and5Saccharomyces cerevisiae, Hansenula polymorpha, Kluyveromyces lactis, Kluyveromyces marxianus, Pichia pastoris, Pichia methanolica, Pichia stipites, Candida boidinii, Schizosaccharomyces pombe, Schwanniomyces occidentalis, Torulaspora delbrueckii, Yarrowia lipolytica, Zygosaccharomyces rouxii,Zygosaccharomyces bailii.. The method of or claim 3 , wherein the yeast is selected from the group consisting of: and6. The method of any of - claim 3 , wherein the enzymatic treatment comprises incubation of the fermentation product with one or more enzymes selected from the group consisting of: lactase claim 3 , β-galactosidase claim 3 , trehalase claim 3 , and invertase.7. The method of any of ...

System and method for manipulation of ion concentration to maximize efficiency of ion exchange

A method for manipulating ion concentration to maximize ion exchange media performance is disclosed herein. First a source liquid is directed through an ion concentrator such as a nanofilter, reverse osmosis membrane, or an evaporator/crystallizer. The ion concentrator separates the source liquid into a concentrate stream and a permeate stream wherein the permeate stream comprises a smaller concentration of ions than the concentrate stream. The concentrate stream and/or the permeate stream (input stream) may then be directed through an ion exchange vessel. The ion exchange vessel receives the input stream, enables ion exchange between the ion exchange media in the vessel and the input stream resulting in a liquid output having a smaller concentration of ions than the input stream.

METHOD AND APPARATUS FOR CONCENTRATION AND CRYSTALLIZATION OF FERMENTABLE CARBOXYLIC ACIDS

A method for concentrating and crystallizing fermentable carboxylic acids, salts, and mixtures thereof may involve the use of carboxylic acids that have a defined temperature dependence of the solubility and of the osmotic pressure. The carboxylic acids may be concentrated by a membrane method and subsequently crystallized out by a cooling crystallization and isolated. In some examples, the membrane method may involve nanofiltration, reverse osmosis, and/or membrane distillation for separation into a concentrate and a permeate. Similarly, an apparatus for implementing such methods may include a nanofiltration, reverse osmosis, and/or membrane distillation unit for concentrating the carboxylic acid, and at least one cooling crystallization unit for crystallizing the carboxylic acid.” 121.-. (canceled)22. A method for concentrating and crystalizing fermentable carboxylic acids , salts , and mixtures thereof , the method comprising: wherein the carboxylic acid has a molar mass in a range from 90 to 210 g/mol,', 'wherein the carboxylic acid has a solubility in water at 20° C. of 4 g/1 to 100 g/l,', 'wherein the carboxylic acid has a relative increase in solubility in a temperature range from 20 to 80° C. of at least 2%/° C. relative to the solubility at 20° C., and', 'wherein a concentrated solution of the carboxylic acid has an osmotic pressure in a temperature range from 20 to 80° C. of less than 80 bar;, 'providing a processed fermentation broth or an aqueous solution of a carboxylic acid,'}concentrating the carboxylic acid in the processed fermentation broth or the aqueous solution by way of a membrane method;subjecting the concentrated processed fermentation broth or the aqueous solution of the carboxylic acid to a cooling crystallization; andisolating crystals of the carboxylic acid.23. The method of comprising concentrating the carboxylic acid in the processed fermentation broth or the aqueous solution by a factor of 1 to 5 up to immediately before attainment of ...

PROCESS FOR PRODUCING, ISOLATING, AND PURIFYING MODIFIED RECOMBINANT PROTEINS

The invention provides for methods and processes for producing, isolating, and purifying modified proteins. In particular, the invention provides for the production, isolation and purification of PEGylated recombinant methionyl human granulocyte colony stimulating factor used for therapeutic purposes. 1. A method for producing recombinant methionyl human granulocyte colony-stimulating factor (r-met-Hu-G-CSF) comprising:(a) contacting cells comprising a nucleic acid encoding r-met-Hu-G-CSF with a culture medium to create a fermentation medium;(b) fermenting the cells under fed-batch conditions causing the cells to produce r-met-Hu-G-CSF;(c) harvesting the cells from the fermentation medium by centrifugation;(d) lysing the cells harvested from the fermentation medium to release inclusion bodies comprising r-met-Hu-G-CSF; and(e) storing the inclusion bodies.2. A method for purifying r-met-Hu-G-CSF from inclusion bodies comprising:(a) suspending inclusion bodies comprising r-met-Hu-G-CSF in a solubilization buffer;(b) oxidizing solubilized r-met-Hu-G-CSF to permit the r-met-Hu-G-CSF to fold and form disulfide bonds;(c) subjecting a product of step (b) to Dowex flow-through chromatography;(d) subjecting a product of step (c) to acid precipitation;(e) subjecting a product of step (d) to anion exchange chromatography;(f) subjecting a product of step (e) to cation exchange chromatography;(g) subjecting a product of step (f) to mixed mode chromatography;(h) concentrating a product of step (g); and(i) exchanging r-met-Hu-G-CSF in the product of step (h) into a buffer by ultrafiltration and diafiltration.3. A method of producing a PEGylated and purified r-met-Hu-G-CSF comprising:(a) contacting a r-met-Hu-G-CSF with a PEGylation reagent under suitable reaction conditions to PEGylate the r-met-Hu-G-CSF;(b) subjecting a product of step (a) to cation exchange chromatography to remove the reaction by-products from PEGylated r-met-Hu-G-CSF;(c) concentrating a product of step (b);(d) ...

REDOX CONTROLLED ELECTROSORPTION AND DECOMPOSITION DEVICE FOR THE PURIFICATION OF BLOOD AND OTHER FLUIDS

Device for removing substances from blood and other fluids such as water, wastewater, chemicals and other biofluids, includes i) an electrocatalytic decomposition filter including a DC power source, a set of electrodes with a catalytic surface or in direct contact with sorbents offering catalytic activity, ii) an electrosorption filter including a DC power source, a set of electrodes, nanostructured sorption material and/or a porous polymer matrix, iii) an inlet for entry of blood or blood plasma or dialysate fluid into the device, iv) an outlet for the removal of purified blood, blood plasma, ultrafiltrate or dialysate fluid from the device, and v) a conduit connecting the inlet with the outlet and holding the electrosorption filter such that the blood, blood plasma, ultrafiltrate or dialysate fluid is forced through the electrosorption and electrocatalytic decomposition filter, and vi) a sensor and control system to safeguard the device from producing oxidative stress. 2. Device according to claim 1 , wherein the electrosorption filter and electrocatalytic decomposition filter are combined into one filter compartment wherein the sorption material is contained in between the electrocatalytic electrodes3. Device according to claim 2 , wherein said electrocatalytic decomposition and electrosorption filter is provided in the form of a cartridge with said electrodes coated with said sorption material or with said electrodes surrounded by a porous envelop containing said sorption material.4. Device according to claim 2 , wherein said electrocatalytic decomposition and electrosorption filter is combined with a permeable envelop to form a filter pad comprising an envelop surrounding a filter pad contents claim 2 , wherein the envelop of said pad comprises a permeable membrane and the contents of said pad comprise said sorption material.5. Device according to claim 1 , wherein said device further comprises a plasmafilter for separating patient blood plasma from patient ...

WATER TREATMENT ASSEMBLY INCLUDING HYPERFILTRATION MODULE AND CATION EXCHANGE RESIN

A water treatment assembly () and method for its operation, comprising a spiral wound hyperfiltration membrane module () connected to: i) a feed line () adapted for connection to a source of pressurized feed water, ii) a permeate line () adapted for connection to a dispenser of treated water and iii) a concentrate line () adapted for connection with a drain; wherein the assembly includes a pressurizable reservoir () containing weak acid cation exchange resin () and further includes at least one valve for selectively diverting flow of pressurized feed water along the feed line (), through the reservoir () and returning to the feed line () prior to passing through the hyperfiltration membrane module (). 1. A water treatment assembly comprising a spiral wound hyperfiltration membrane module connected to:i) a feed line adapted for connection to a source of pressurized feed water,ii) a permeate line adapted for connection to a dispenser of treated water andiii) a concentrate line adapted for connection with a drain;wherein the assembly is characterized by comprising a pressurizable reservoir containing weak acid cation resin and further comprising at least one valve for selectively diverting flow of pressurized feed water along the feed line, through the reservoir and returning to the feed line prior to passing through the hyperfiltration membrane module.2. The water treatment assembly of further characterized by comprising a first path that bypasses said pressurizable reservoir claim 1 , a second path that passes through said pressurizable reservoir claim 1 , and a mechanically biased valve within the first path that is normally open but may be closed to divert the flow of water through the pressurizable reservoir.3. The water treatment assembly of claim 2 , wherein the resistance to flow through the first path is less than 10% of the resistance to flow through the second path.4. The assembly of wherein the pressurizable reservoir containing weak acid cation exchange ...

METHOD FOR PURIFYING OSES WITHOUT ADJUSTING pH

The method for purifying oses from hemicellulose originating from lignocellulosic biomass includes eliminating the cellulose matrix and the solid residues and/or the suspended materials from the acid hydrolysate containing oses in order to obtain a clarified hydrolysate, and subjecting the clarified hydrolysate, without adding any basic chemical reagent to increase the pH to at least one step of ultrafiltration and/or to at least one step of nanofiltration, so as to obtain a filtrate containing the majority of the pentoses and a retentate containing the species likely to precipitate under the effect of an increase in the pH. The filtrate is treated by at least one step of electrodialysis so as to recover the acid catalyst from an acid-supplemented solution, and obtain a deacidified filtrate. 1. A method for purification of oses being comprised of hemicellulose derived from lignocellulosic biomasses , said oses being contained in an acid hydrolysate obtained by partial hydrolysis of lignocellulosic biomasses by at least one acid catalyst , said acid hydrolysate being comprised of a cellulosic matrix , and at least one of solid residues and suspended matters , said method comprising the following steps:removing the cellulosic matrix and the at least one of solid residues and the suspended matters from the acid hydrolysate, in order to obtain a clarified hydrolysate;subjecting said clarified hydrolysate, without any addition of a basic chemical reagent to increase the pH, to at least one ultrafiltration step and/or to at least one nanofiltration step, so as to obtain a filtrate containing the majority of the pentoses and a retentate containing the species likely to precipitate under the action of an increase in pH; andtreating said filtrate with at least one electrodialysis step so as to recover the acid catalyst in an acid-enriched solution and to obtain a deacidified filtrate.2. The method for purification claim 1 , according to claim 1 , wherein claim 1 , prior to ...

SUBSEA EQUIPMENT CLEANING SYSTEM AND METHOD

The invention concerns a subsea water processing system comprising an electrochemical unit that uses raw or treated seawater to generate high pH and low pH solutions that are used to clean at least one subsea process apparatus during a cleaning cycle by circulation through the at least one subsea process apparatus via acid or base flow lines connecting the electrochemical unit with the subsea process apparatus on-site. 1. A subsea water processing system comprising an electrochemical unit that uses raw or treated seawater or oil field produced water to generate high pH and low pH solutions that are used to clean at least one subsea process apparatus during a cleaning cycle by circulation through the at least one subsea process apparatus via acid or base flow lines connecting the electrochemical unit with the subsea process apparatus on-site.2. The system of claim 1 , wherein the at least one subsea process apparatus is selected from the group consisting of membrane separation module claim 1 , heat exchangers claim 1 , components of the hydrocarbon production system claim 1 , pipelines claim 1 , injection or production wells claim 1 , pumps for injecting acid into the reservoir for reservoir stimulation claim 1 , and water injection systems.3. The system of claim 1 , wherein the high pH solution has a pH higher than 9.5 claim 1 , and the low pH solution has a pH lower than 4.4. The system of claim 1 , wherein the electrochemical unit is an electrolysis unit without membranes.5. The system of claim 1 , wherein the electrochemical unit is an electrolysis unit with membranes.6. The system of claim 1 , wherein the electrochemical unit is a bipolar membrane electro-dialysis unit.7. The system of claim 1 , wherein the electrochemical unit is a bipolar membrane electro-dialysis unit with 2-compartment design or 3-compartment design.8. The system of claim 1 , wherein the electrochemical unit can supply low PH solution for injection into the reservoir formation for ...

Liver support system

An artificial, extracorporeal system for liver replacement and/or assistance, comprises a liver dialysis device for conducting hemodialysis on a patient suffering from liver failure. The liver dialysis device comprises a first standard hollow fiber membrane dialyzer which does not allow passage of an essential amount of albumin over the membrane wall and which is perfused with the patient's blood, and a second hollow fiber membrane dialyzer which allows the passage of essential but defined amounts of albumin over the membrane wall and which receives the blood of the first standard hemodialyzer. The filtrate space is closed off from the lumen space of the hollow fibers and is populated by adsorbent material which may comprise one or more different adsorbents.

ULTRAPURE WATER PRODUCING METHOD

A method for producing ultrapure water includes supplying raw water (industrial water, tap water, well water, or used ultrapure water discharged from semiconductor plants) to a pretreatment system for treating the raw water to produce water, supplying the water to a primary water purification system having a reverse osmosis membrane separation unit to produce a primarily purified water, and supplying the primarily purified water to a secondary purification system to produce ultrapure water.

METHOD FOR PURIFYING WATER AS WELL AS PLANT SUITABLE FOR SAID METHOD

The present invention relates to a method for purifying water using at least one unit for trapping one or more ions and at least one membrane filtration unit, wherein an aqueous stream is withdrawn from a source and is fed to the aforementioned unit for trapping one or more ions, wherein the aqueous stream leaving the aforementioned unit is fed to the aforementioned membrane filtration unit, and at least one concentrate stream and one permeate stream are obtained in said membrane filtration unit, wherein at least part of the aforementioned one or more ions that are trapped is added to the aforementioned permeate stream to obtain a permeate stream enriched with one or more ions. 1. A method for purifying water using at least one unit for trapping one or more ions and at least one membrane filtration unit , wherein an aqueous stream is withdrawn from a source and is fed to the unit for trapping one or more ions , wherein the aqueous stream leaving the unit is fed to the membrane filtration unit , and at least one concentrate stream and one permeate stream are obtained in said membrane filtration unit , wherein at least part of the one or more ions that are trapped is added to the permeate stream to obtain a permeate stream enriched with one or more ions.2. The method according to claim 1 , wherein the concentrate stream is fed to a unit for generating a basic stream and an acid stream claim 1 , wherein the unit performs bipolar membrane electrodialysis.3. (canceled)4. The method according to claim 2 , wherein the acid stream is applied in a regeneration step of the unit for trapping one or more ions claim 2 , wherein an effluent stream obtained in the regeneration step is fed to a second unit for trapping one or more ions claim 2 , wherein at least part of the effluent stream obtained from the second unit for trapping one or more ions is fed to the permeate stream claim 2 , and wherein the effluent stream is stored and is fed to the permeate stream.56-. (canceled)7. ...

ACIDIC TREATMENT LIQUID PROCESSING APPARATUS, ACIDIC TREATMENT LIQUID PROCESSING METHOD, SURFACE TREATMENT SYSTEM, AND SURFACE TREATMENT METHOD

An acidic treatment liquid processing apparatus includes: a tank having an interior space; a diaphragm permeable to a metal cation and separating the interior space of the tank into a first chamber and a second chamber; a first electrode disposed in the first chamber; a second electrode disposed in the second chamber; a power supply configured to apply a voltage while using the first electrode as an anode and the second electrode as a cathode; a first liquid passing part configured to pass an acidic treatment liquid containing a dichromate ion and a metal cation into the first chamber; and a second liquid passing part configured to pass an acid aqueous solution into the second chamber. 1. An acidic treatment liquid processing apparatus , comprising:a tank having an interior space;a diaphragm permeable to a metal cation and separating the interior space of the tank into a first chamber and a second chamber;a first electrode disposed in the first chamber;a second electrode disposed in the second chamber;a power supply configured to apply a voltage while using the first electrode as an anode and the second electrode as a cathode;a first liquid passing part configured to pass an acidic treatment liquid containing a dichromate ion and a metal cation into the first chamber; anda second liquid passing part configured to pass an acid aqueous solution into the second chamber.2. (canceled)3. (canceled)4. The acidic treatment liquid processing apparatus according to claim 1 , further comprising:a data acquisition part configured to acquire data indicating a breaking state of the diaphragm; anda control part configured to receive the data acquired by the data acquisition part, and control the power supply and the first liquid passing part,wherein the control part is configured to determine whether the diaphragm breaks based on the data acquired by the data acquisition part, and if it is determined that the diaphragm breaks, stop the applying of the voltage and the passing of ...

Process for preparing chemical liquid of silylating agent and surface treatment method

A process for preparing a chemical liquid of a silylating agent that has a reduced metal impurity concentration, and a surface treatment method using a chemical liquid of a silylating agent obtained by the preparation process. The process includes reducing metal impurities contained in an untreated chemical liquid of a silylating agent using an ion-exchange resin membrane that has been brought into contact with an organic solvent in advance. A surface treatment method that hydrophobizes a substrate surface includes exposing, to the substrate surface, a chemical liquid of a silylating agent obtained by the above process for preparing a chemical liquid of a silylating agent.

ION-EXCHANGE PROCESS

A process for ion-exchanging an exchangeable-ion containing solid material involves several steps. There is a bipolar membrane electrodialysis step, which involves subjecting an aqueous ion-containing solution to a bipolar membrane electrodialysis to produce an acid liquid. The process also contains an ion-exchange step, during which the exchangeable-ion containing solid material is contacted with the acid liquid to conduct ion-exchange to produce a slurry containing the ion-exchanged solid material. It further include a solid-liquid separation step, during which the slurry containing the ion-exchanged solid material is subject to a solid-liquid separation to produce a solid phase and a liquid phase. The pH value of the liquid phase is adjusted to 4-6.5. The pH-adjusted liquid phase is further subject to a solid-liquid separation to produce a treatment liquid. 1. A process for ion-exchanging an exchangeable-ion containing solid material , characterized in that said process comprises:a bipolar membrane electrodialysis step, which comprises subjecting an aqueous ion-containing solution to a bipolar membrane electrodialysis to produce an acid liquid;an ion-exchange step, which comprises contacting the exchangeable-ion containing solid material with the acid liquid and conducting the ion-exchange to produce a slurry containing the ion-exchanged solid material;a solid-liquid separation step, which comprises subjecting the slurry containing the ion-exchanged solid material to a solid-liquid separation to produce a solid phase and a liquid phase, adjusting the liquid phase to a pH of 4-6.5, and subjecting the pH-adjusted liquid phase to a solid-liquid separation to produce a treatment liquid;wherein the treatment liquid can replace at least a part of the aqueous ion-containing solution in the bipolar membrane electrodialysis step;wherein the aqueous ion-containing solution has an anion concentration or a cation concentration of 0.01-10 mol/L;wherein oxalic acid exists in ...

Aqueous hydrogen peroxide purification method and purification system

A purification method for an aqueous hydrogen peroxide solution includes subjecting the aqueous hydrogen peroxide solution to a reverse osmosis membrane separation treatment with a high-pressure reverse osmosis membrane separation device. The high-pressure reverse osmosis membrane has a denser skin layer on the membrane surface and is therefore lower in an amount of membrane permeate water per unit operating pressure but higher in the rejection rate of TOC and boron, as compared with a low-pressure or ultralow-pressure reverse osmosis membrane. The high-pressure reverse osmosis membrane permeate water is preferably further subjected to an ion exchange treatment with an ion exchange device including two or more columns packed with gel-type strong ion exchange resins.

INTEGRATED ULTRAFILTRATION MEMBRANE AND ION-EXCHANGE FILTRATION SYSTEM

An ion-exchange and ultrafiltration filter system having an exterior housing having an inlet and an outlet with an ultrafiltration membrane provided within the housing along a central axis about a central portion of the housing with an ion-exchange membrane provided within the housing between the ultrafiltration membrane and the housing. The ion-exchange and ultrafiltration filter system being capable of being configured so as to provide two-step filtration in a plurality of modes, either ion-exchange to ultrafiltration, or ultrafiltration to ion-exchange. 1. An ion-exchange and ultrafiltration filter system , the system comprising:a housing having an inlet and a clean outlet;an ultrafiltration membrane provided within the housing, the ultrafiltration membrane being provided about a central portion of the housing; andan ion-exchange membrane provided within the housing between the ultrafiltration membrane and the housing.2. The ion-exchange and ultrafiltration filter system of claim 1 , further arranged such that a portion of a contaminated stream being directed through the inlet passes first through the ion-exchange membrane and then through the ultrafiltration membrane before exiting the clean outlet.3. The ion-exchange and ultrafiltration filter system of claim 1 , further arranged such that a contaminated stream being directed through the inlet passes first through the ultrafiltration membrane at a first end claim 1 , at least of portion of which is then directed through the ion-exchange membrane before exiting the clean outlet.4. The ion-exchange and ultrafiltration filter system of claim 3 , further comprising:a waste outlet provided at an opposing end being configured to receive an unfiltered portion of the contaminated stream.5. The ion-exchange and ultrafiltration filter system of claim 1 , wherein the ion-exchange membrane includes a plurality of layers.6. The ion-exchange and ultrafiltration filter system of claim 5 , wherein each layer is sealed from any ...

CHEMICAL LIQUID MANUFACTURING APPARATUS

A chemical liquid manufacturing apparatus, including a first system and a second system, is provided. The first system includes at least one first filtration medium, selected from a first filter, a first ion exchange membrane and a first ion adsorption membrane, wherein the first system is configured to process a material of at least one time. The second system includes at least one second filtration medium, selected from a second filter, a second ion exchange membrane and a second ion adsorption membrane, wherein the second system is configured for recirculation and to process the material of at least two times. 1. A chemical liquid manufacturing apparatus , comprising:a first system configured to process a material, the first system comprising at least one first filtration medium, selected from a first filter, a first ion exchange membrane and a first ion adsorption membrane, wherein the first system is configured to process the material of at least one time; anda second system configured to process the material, the second system comprising at least one second filtration medium, selected from a second filter, a second ion exchange membrane and a second ion adsorption membrane, wherein the second system is configured for a recirculation and to process the material of at least two times.2. The chemical liquid manufacturing apparatus of claim 1 , wherein the first system is positioned at an upstream side of the second system claim 1 , and the material is processed by the first system before being processed by the second system.3. The chemical liquid manufacturing apparatus of claim 1 , wherein the first system is configured for a single pass.4. The chemical liquid manufacturing apparatus of claim 1 , wherein the at least one second filtration medium comprises the second filter claim 1 , and the second filter is a pure sieving filter having a pore size of the second filter is about 10 nm or less.5. The chemical liquid manufacturing apparatus of claim 1 , wherein the ...

ULTRAPURE WATER PRODUCTION APPARATUS AND ULTRAPURE WATER PRODUCTION METHOD

The present invention provides an apparatus and method for producing ultrapure water of extremely high purity that sufficiently meets the requirement for its quality at low production cost with reduced footprint. The apparatus for producing ultrapure water includes a pretreatment system, a primary water purification system, and a subsystem, wherein the primary water purification system includes a high-pressure reverse osmotic membrane separation unit, a degassing unit, an ultraviolet oxidation unit, and an ion-exchange unit in this order. 1. An apparatus for producing ultrapure water comprising a pretreatment system , a primary water purification system , and a subsystem , wherein the primary water purification system comprises a high-pressure reverse osmotic membrane separation unit , a degassing unit , an ultraviolet oxidation unit , and an ion-exchange unit in this order.2. The apparatus according to claim 1 , wherein the high-pressure reverse osmotic membrane separation unit exhibits a pure water flux of 0.6 to 1.3 m/m/day under an effective transmembrane pressure of 2.0 MPa and 25° C.3. The apparatus according to claim 1 , wherein the ion-exchange unit is any one of the following reusable ion-exchange units A) to D):A) a two-bed two-tower reusable ion-exchange unit comprising a cation-exchange tower filled with a strong-acid cation-exchange resin and an anion-exchange tower filled with a strong-base anion-exchange resin, the towers being connected in series;B) a two-bed one-tower reusable ion-exchange unit comprising a single tower filled with a strong-acid cation-exchange resin and a strong-base anion-exchange resin such that the resins are placed in different beds;C) a mixed-bed reusable ion-exchange unit comprising a single tower filled with a homogeneous mixture of a strong-acid cation-exchange resin and a strong-base anion-exchange resin; andD) a reusable ion-exchange unit comprising one or more electric reusable deionization units connected in series.4. A ...

IMPROVED REVERSE OSMOSIS OR NANOFILTRATION PROCESS FOR CLEANING WATER

A system for cleaning feed water of variable quality, the system comprising an inlet for selectively delivering feed water (FW) to one or other of at least two feed chambers (), each feed chamber having a delivery pipe () for delivering feed water to a reverse osmosis or nanofiltration (); a pump () to deliver the feed water from one of the chambers () through its as sociated delivery pipe () to the reverse osmosis or nanofiltration () to create a concentrated feed stream and a product water stream (PW);return pipes (R, R) for selectively returning the concentrated feed stream to one or other of the at least two feed chambers (); a product water outlet for removal of the product water (PW); and means for switching the delivery of the concen trated feed stream between the selectable return pipes (R, R) upon detection of a predetermined reduction in the efficiency of the RO or NF process within one or other of the feed chambers (). The pressure of the concentrated feed stream is reduced to atmo spheric pressure prior to its delivery back to the chamber and the feed stream passes through a desaturation unit (). 1. A method of cleaning feed water (FW) of variable quality , the method comprising:{'b': '2', '(a) delivering feed water (FW) to one of at least two feed chambers ();'}{'b': 2', '8, '(b) pumping feed water from one of the feed chambers () through a reverse osmosis (RO) or nanofiltration (NF) membrane () to create a concentrated feed stream and a product water stream (PW);'}(c) reducing the pressure of the concentrated feed stream;{'b': 2', '8, '(d) returning the concentrated feed stream to the original feed chamber () for delivery back through the reverse osmosis or nanofiltration ();'}{'b': 4', '2, '(e) switching the return delivery of the concentrated feed stream to the at least one other feed chamber () upon detecting a predetermined reduction in the efficiency of the RO or NF process within the original feed chamber ();'}{'b': 2', '4', '8', '4, '(e) ...

Chemical extraction from an aqueous solution

A method of chemical extraction from an aqueous solution includes receiving an aqueous solution including dissolved inorganic carbon. The method also includes increasing a pH of a first portion of the aqueous solution to form a basic solution. The basic solution is then combined with a second portion of the aqueous solution to precipitate calcium salts. The calcium salts are then collected.

ANALYZING METHOD AND ANALYZING APPARATUS FOR UREA

The analyzing method for quantifying urea in a sample solution includes: a pretreatment step of pretreating the sample solution with at least one of a membrane device including a reverse osmosis membrane and an ion exchange device including an ion exchanger; and an analyzing step of analyzing a target substance in the pretreated sample solution. The analyzing step is based on, for example, flow injection analysis (FIA), and includes a step of quantifying the target substance by measuring the absorbance of a liquid containing a substance generated by reacting the target substance with a reagent. 1. An analyzing method of quantifying urea in a sample solution , the method comprising:pretreating a sample solution with at least one of a membrane device including a reverse osmosis membrane and an ion exchange device including an ion exchanger; andanalyzing by quantifying urea in the pretreated sample solution.2. The analyzing method as claimed in claim 1 , wherein an elimination rate of urea in the membrane device is 20% or less.3. The analyzing method as claimed in claim 1 , wherein a salt rejection rate of the reverse osmosis membrane is 99.0% or less with respect to sodium chloride.4. The analyzing method as claimed in claim 1 , wherein a filtering process is performed on the sample solution during the pretreating.5. The analyzing method as claimed in claim 1 , wherein the ion exchanger comprises at least one of a granular anion exchange resin claim 1 , a monolithic anion exchange resin claim 1 , and an anion exchange fiber.6. The analyzing method as claimed in claim 5 , wherein during the pretreating claim 5 , the sample solution is passed through the ion exchange device provided in a preceding stage or a following stage of the membrane device.7. The analyzing method as claimed in claim 1 , wherein a ratio of urea in the sample solution to be removed in the membrane device is obtained in advance claim 1 , and a quantitative value of urea obtained during the analyzing ...

FILTER DEVICE, PURIFICATION DEVICE, CHEMICAL SOLUTION PRODUCTION METHOD

A filtering device is for obtaining a chemical liquid by purifying a liquid to be purified and has an inlet portion, an outlet portion, a filter A, a filter B different from the filter A, and a flow path extending from the inlet portion to the outlet portion, in which the filter A and the filter B are arranged in series between the inlet portion and the outlet portion and have, and the filter A is selected from the group consisting of predetermined filters A1, A2, and A3.

FILTERING DEVICE, PURIFICATION DEVICE, AND METHOD FOR MANUFACTURING CHEMICAL LIQUID

A filtering device is used for obtaining a chemical liquid by purifying a liquid to be purified and includes an inlet portion, an outlet portion, a filter A, at least one filter B different from the filter A, and a flow path that includes the filter A and the filter B arranged in series and extends from the inlet portion to the outlet portion. The filter A has a porous membrane made of ultra-high-molecular-weight polyethylene and a resin layer disposed to cover at least a portion of the surface of the porous membrane, and the resin layer includes a resin having a neutral group or an ion exchange group. 1. A filtering device for obtaining a chemical liquid by purifying a liquid to be purified , the filtering device comprising:an inlet portion;an outlet portion;a filter A;at least one filter B different from the filter A; anda flow path which includes the filter A and the filter B arranged in series and extends from the inlet portion to the outlet portion,wherein the filter A has a porous membrane made of ultra-high-molecular-weight polyethylene and a resin layer disposed to cover at least a portion of a surface of the porous membrane, andthe resin layer includes a resin having a neutral group or an ion exchange group.2. The filtering device according to claim 1 ,wherein the filter B includes at least one filter BU disposed on an upstream side of the filter A on the flow path.3. The filtering device according to claim 2 ,wherein the at least one filter BU includes a filter having a pore size equal to or greater than 1 nm.4. The filtering device according to claim 2 ,wherein the at least one filter BU contains a resin having a second ion exchange group.5. The filtering device according to claim 1 ,wherein the resin having a neutral group or an ion exchange group has a neutral group, andthe filter A is disposed on a downmost stream side in the flow path.6. The filtering device according to claim 1 ,wherein the resin having a neutral group or an ion exchange group has a ...

SPRAY-DRIED MIXTURE OF HUMAN MILK OLIGOSACCHARIDES

Disclosed are spray-dried powders containing a mixture of structurally distinct human milk oligosaccharides, methods for the production of said spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions containing said spray-dried powder. 1. A spray-dried powder comprising a mixture of structurally distinct human milk oligosaccharides.2. The spray-dried powder according to claim 1 , wherein the structurally distinct HMOs of the mixture are selected from the group consisting of 2′-FL claim 1 , 3-FL claim 1 , LNT claim 1 , LNnT claim 1 , LNFPI claim 1 , 3′-SL claim 1 , 6′-SL claim 1 , LST-a claim 1 , LST-b claim 1 , LST-c and DSLNT.3. The spray-dried powder according to claim 1 , wherein said spray-dried powder further comprises at least one monosaccharide claim 1 , said at least one monosaccharide being optionally selected from the group consisting of L-fucose and N-acetylneuraminic acid.4. The spray-dried powder according to claim 1 , wherein the spray-dried powder comprises at least 80%-wt. claim 1 , at least 85%-wt. claim 1 , at least 90%-wt. claim 1 , at least 93%-wt. claim 1 , at least 95%-wt. or at least 98%-wt. human milk oligosaccharides.5. The spray-dried powder according to claim 1 , wherein at least one HMO of the mixture claim 1 , optionally all HMOs of the mixture claim 1 , optionally the at least one monosaccharide claim 1 , are present in amorphous form.6. The spray-dried powder according to claim 3 , wherein the at least one monosaccharide claim 3 , optionally all monosaccharides are present in amorphous form.7. The spray-dried powder according to claim 1 , wherein the spray-dried powder contains ≤15%-wt. of water claim 1 , optionally ≤10%-wt. of water claim 1 , optionally ≤7%-wt. of water claim 1 , optionally ≤5%-wt. of water.8. A process for manufacture of a spray-dried powder as defined in claim 1 , wherein the process comprises:a) purifying at least one of the structurally distinct HMOs from a ...

SPRAY-DRIED SIALYLLACTOSE

Disclosed is a method for the manufacture of a spray-dried powder consisting essentially of 3′-SL and/or 6′-SL, the spray-dried powder, its use for the manufacture of nutritional compositions, and nutritional compositions containing the spray-dried powder. 1. A spray-dried powder comprising or consisting essentially of 3′-SL and/or 6′-SL which has been produced by microbial fermentation.2. The spray-dried powder according to claim 1 , wherein the spray-dried powder comprises at least 80%-wt. claim 1 , at least 85%-wt. claim 1 , at least 90%-wt. claim 1 , at least 93%-wt. claim 1 , at least 95%-wt. or at least 98%-wt. 3′-SL and/or 6′-SL.3. The spray-dried powder according to claim 1 , wherein the 3′-SL and/or 6′-SL is present in amorphous form.4. The spray-dried powder according to claim 1 , wherein the spray-dried powder contains comprises 15%-wt. of water claim 1 , optionally 10%-wt. of water claim 1 , optionally 7%-wt. of water claim 1 , optionally 5%-wt. of water.5. The spray-dried powder according to claim 1 , wherein the spray-dried powder is free of genetically-engineered microorganisms and nucleic acid molecules derived from genetically-engineered microorganisms.6. A process for the manufacture of a spray-dried powder as defined in claim 1 , the process comprises:a) purifying the 3′-SL and/or 6′-SL from a fermentation broth;b) providing an aqueous solution containing the 3′-SL and/or 6′-SL of a); andc) subjecting the solution of b) to spray-drying.7. The process according to claim 6 , wherein the purifying the 3′-SL and/or 6′-SL from a fermentation broth a) includes one or more ofi) removing the microbial cells from the fermentation broth to obtain a cleared process stream;ii) subjecting the cleared process stream to at least one ultrafiltration;iii) treating the cleared process stream at least one time with a cation exchange resin and/or at least one time with an anion exchange resin;iv) subjecting the cleared process stream to at least one nanofiltration ...

WATER CONDITIONING SYSTEMS

A portable water conditioning system is provided that includes a water conditioner, a first sensor, a second sensor, and a controller. The water conditioner has a plurality of conditioning stages that condition water. The plurality of conditioning stages include, in a direction of flow of the water through the water conditioner, a reverse osmosis stage and a deionizing stage. The first sensor detects a first condition of the water before the reverse osmosis stage. The second sensor detects a second condition of the water after the reverse osmosis stage. The controller is in communication with the first and second sensors and determines a health status of the reverse osmosis stage based the first and second conditions. The first and second conditions each include a level of total dissolved solids of the water. 1. A method for conditioning water , the method comprising:flowing water through a water conditioner of a portable water conditioning system, wherein a direction of flow is through the water conditioner, a reverse osmosis stage, and a deionizing stage;detecting a first condition of the water before the reverse osmosis stage of the portable water conditioning system;detecting a second condition of the water after the reverse osmosis stage, the first condition and the second condition each comprising a level of total dissolved solids in the water;determining a percent rejection of the reverse osmosis stage based on the first and second conditions when a pressure on the reverse osmosis stage is at a known state; anddiverting a portion of the water exiting the reverse osmosis stage out of the portable water conditioning system and maintaining the pressure at the known state.2. The method of claim 1 , further comprising providing conditioned water having a desired condition from the portable water conditioning system.3. The method of claim 2 , wherein the desired condition is based on a location of the portable water conditioning system.4. The method of claim 1 , ...

MULTILAYER NANO-CELL

A multilayer nano-cell includes an innermost water phase core including biomolecules in an aqueous solution; a first layer, including an oil phase layer encapsulating the innermost water phase core, thereby forming a water-in-oil structure, the oil phase layer including caprylic/capric triglyceride and macrogol-35-glycerol-rizinoleat; a second layer, including a water phase layer encapsulating the first layer, the water phase layer including hyaluronic acid, Cu-GHK tripeptide, palmitoyl-KTTKS pentapeptide, and hexapeptide argireline; a third layer, including another oil phase layer encapsulating the second layer; a fourth layer, including another water phase layer encapsulating the third layer; a fifth layer, including another oil phase layer encapsulating the fourth layer; and a sixth layer, including an outmost cream layer encapsulating the fifth layer. 1. A multilayer nano-cell , comprising:an innermost water phase core including biomolecules in an aqueous solution, the biomolecules including hyaluronic acid, and the aqueous solution including Cu-GHK tripeptide, palmitoyl-KTTKS pentapeptide, and hexapeptide argireline;a first layer, including an oil phase layer encapsulating the innermost water phase core, thereby forming a water-in-oil structure, wherein the oil phase layer includes caprylic/capric triglyceride and macrogol-35-glycerol-rizinoleat;a second layer, including a water phase layer encapsulating the first layer, the water phase layer including hyaluronic acid, Cu-GHK tripeptide, palmitoyl-KTTKS pentapeptide, and hexapeptide argireline;a third layer, including another oil phase layer encapsulating the second layer;a fourth layer, including another water phase layer encapsulating the third layer;a fifth layer, including another oil phase layer encapsulating the fourth layer; anda sixth layer, including an outmost cream layer encapsulating the fifth layer.2. (canceled)3. The multilayer nano-cell according to claim 1 , wherein:the multilayer nano-cell has ...

Method for purifying and recovering solvent from ion exchange processes

The invention relates to a system and method of use for concentrating a solution that is eluted from an ion exchange process (elution solution) during an ion exchange regeneration using the osmotic pressure of the salt saturator. This method recovers solvent from the elution solution that could be used in a future ion exchange regeneration process. The concentration of the elution solution may include the precipitation and removal of solids from the elution solution.

PROTEIN HYDROLYSATE AND PROCESS FOR MAKING SUCH

The invention relates to a protein hydrolysate and a process for making such protein hydrolysate. In particular the invention relates to a collagen hydrolysate and a process for making such collagen hydrolysate. Further the invention relates to a food, pet food, cosmetic, pharmaceutical or technical application comprising the protein hydrolysate of the present invention and further food, pet food, cosmetic, pharmaceutical or technical constituents. 1. A protein hydrolysate characterized in that it hasa. A moisture content of 4 to 12%,b. A protein content of from 85 wt % or more,c. A hydration time of 7 seconds or less, andd. A dissolution time of 250 seconds or less.2. The protein hydrolysate of claim 1 , characterized in that it has a bulk density of 240 g/l or higher.3. The protein hydrolysate of or characterized in that the protein hydrolysate is collagen hydrolysate.4. The protein hydrolysate of any one of the previous claims further characterized in that it has an average molecular weight of from 300 to 15000 Da.5. The protein hydrolysate of any one of the previous claims further characterized in that it has a d50 particle size of from 100 to 1000 μm.6. The protein hydrolysate of any one of the previous claims further characterized in that the protein hydrolysate is agglomerated.7. A process to produce a protein hydrolysate characterized in that it comprises the steps of:a. Incubating a composition comprising protein with a peptidase to obtain a composition comprising protein hydrolysate, andb. Optionally demineralizing the composition comprising protein hydrolysate, andc. Adjusting, preferably increasing, the dry substance content of the composition comprising protein hydrolysate to a dry substance of from 40 to 65% to obtain a concentrated composition comprising protein hydrolysate, andd. Drying the concentrated composition comprising protein hydrolysate to obtain a dried protein hydrolysate, ande. Agglomerating the dried protein hydrolysate, andf. Collecting ...

Method and apparatus for treatment of a fluid system

A method for treating a fluid by providing raw fluid to a process tank, adding an ion exchange resin to the process tank to form a raw fluid/ion exchange resin mixture, removing treated fluid from the process tank through a membrane filter located within the process tank, and regenerating the ion exchange resin within the process tank. The method may be set up as a batch process or as a continuous process using a magnetic ion exchange resin and continuous withdrawal of the magnetic ion exchange resin from the process tank by use of a magnetic separator. The method may also consist of reusing the regenerant in multiple regeneration steps and periodically filtering the regenerant to restore its regenerative properties. Alternatively, an upflow bed of ion exchange resin may be used to treat the raw fluid before membrane filtration.

薬液を処理するための方法

薬液を処理するための方法を提供する。該方法は、少なくとも１つの濾過媒体を含むシステムを提供することと、約１０ｐｐｂ以下の鉄（Ｆｅ）とカルシウム（Ｃａ）の含有量を有する処理液でシステムを処理することと、処理工程の後に上記システムをその内に有する装置を用いて薬液を処理することとを少なくとも含む。

廃水浄化システム、洗浄装置及びインクジェットプリンタシステム

【課題】残渣の除去を低減するとともにＲＯ膜の濾過効率の低下やＲＯ膜の損傷を抑制する 【解決手段】インクジェットプリンタ１１を用いて捺染印刷されたテキスタイルＴを洗浄する洗浄装置１３から排出された廃水が貯留される廃水タンク２１と、廃水タンク２１内に染料を分解する酵素及び微生物を投入する酵素／微生物投入装置２６と、廃水タンク２１内にｐＨ調整剤を投入するｐＨ調整剤投入装置２７と、廃水タンク２１内の廃水を攪拌する攪拌装置２８と、廃水タンク２１を保温する保温装置２９と、ＲＯ膜を用いたクロスフロー濾過により廃水を濾過する濾過装置２２と、廃水タンク２１から濾過装置２２に廃水を圧送するポンプ２３と、イオン交換樹脂に濾過水を接触させてイオンを除去するイオン除去装置２４と、活性炭に濾過水を接触させて脱色する脱色装置２５と、を備えている。 【選択図】図１

한외여과 및 이온 교환에 의한 슬러리 구리 폐수의 처리

0.75㎛ 미만의 수치 가중 평균 크기를 가진 연마재 입자 및 용해된 구리를 포함하는 폐스트림을 구리 CMP 공정으로부터 처리하기 위한 방법은 폐스트림을 급수 탱크에 도입하는 단계, 폐스트림을 급수 탱크로부터 한외여과 모듈로 흘리는 단계, 폐스트림을 한외여과 모듈의 막을 통해 여과시켜서 고형물이 없는 여과수를 형성하는 단계, 고형물이 없는 여과수를 한외여과 모듈로부터 이온 교환 장치를 통해 향하게 하여 용해된 구리를 제거하고 폐스트림의 구리 농도보다 더 낮은 구리 농도를 가진 처리된 수용성 용액을 생성하는 단계, 한외여과 모듈의 막을 역세척하여 한외여과 모듈의 막으로부터 슬러리 고형물을 제거하는 단계, 및 제거된 슬러리 고형물과 처리된 수용성 용액을 결합하여 환경으로 배출하는 데 적합한 구리 농도를 가진 결합된 배출 스트림을 형성하는 단계를 포함한다.

Filtration device, purification device, and method for producing a chemical solution

우수한 결함 억제 성능을 갖는 약액을 제조 가능한 여과 장치의 제공을 과제로 한다. 또, 정제 장치, 및 약액의 제조 방법의 제공도 과제로 한다. 여과 장치는, 유입부와, 유출부와, 필터 A와, 필터 A와는 상이한 적어도 1개의 필터 B와 필터 A 및 필터 B가 직렬로 배치된 유입부로부터 유출부에 이르는 유통로를 갖는, 피정제액을 정제하여 약액을 얻기 위한 여과 장치이며, 필터 A는, 초고분자량 폴리에틸렌제의 다공성막과, 다공성막의 표면의 적어도 일부를 덮도록 배치된 수지층을 갖고, 수지층은, 중성기 또는 이온 교환기를 갖는 수지를 포함한다.

SPRAY DRIED BREAST MILK OLIGOSACCHARIDE MIXTURE

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2020 119 954 A (51) МПК A23L 33/10 (2016.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2020119954, 07.12.2018 (71) Заявитель(и): ЙЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ (DE) Приоритет(ы): (30) Конвенционный приоритет: 08.12.2017 EP 17206124.4; 08.12.2017 EP 17206159.0; 08.12.2017 EP 17206223.4; 11.12.2017 EP 17206414.9; 08.02.2018 EP 18155669.7 (72) Автор(ы): ЙЕННЕВАЙН, Штефан (DE) R U (43) Дата публикации заявки: 10.01.2022 Бюл. № 1 2 0 2 0 1 1 9 9 5 4 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 08.07.2020 (86) Заявка PCT: EP 2018/083968 (07.12.2018) (87) Публикация заявки PCT: R U Адрес для переписки: 197101, Санкт-Петербург, а/я 128, "АРСПАТЕНТ", М.В. Хмара (54) ВЫСУШЕННАЯ РАСПЫЛЕНИЕМ СМЕСЬ ОЛИГОСАХАРИДОВ ГРУДНОГО МОЛОКА (57) Формула изобретения 1. Высушенный распылением порошок, содержащий смесь различающихся по структуре олигосахаридов грудного молока (НМО). 2. Высушенный распылением порошок по п. 1, где различающиеся по структуре НМО в данной смеси выбраны из группы, состоящей из 2'-фукозиллактозы (2'-FL), 3'фукозиллактозы (3-FL), лакто-N-тетраозы (LNT), лакто-N-неотетраозы (LNnT), лактоN-фукопентаозы I (LNFPI), 3'-сиалиллактозы (3'-SL), 6'-сиалиллактозы (6'-SL), сиалиллакто-N-тетраозы a (LST-a), сиалиллакто-N-тетраозы b (LST-b), сиалиллакто-Nтетраозы с (LST-c) и дисиалиллакто-N-тетраозы (DSLNT). 3. Высушенный распылением порошок по п. 1 или 2, где указанный высушенный распылением порошок дополнительно содержит по меньшей мере один моносахарид, причем указанный по меньшей мере один моносахарид предпочтительно выбран из группы, состоящей из L-фукозы и N-ацетилнейраминовой кислоты. 4. Высушенный распылением порошок по любому из пп. 1-3, где указанный высушенный распылением порошок содержит по меньшей мере 80 мас.%, по меньшей мере 85 мас.%, по меньшей мере 90 мас.%, по меньшей мере 93 мас.%, по меньшей мере 95 мас.% или по меньшей мере 98 мас.% олигосахаридов ...

Vinylbenzene-styrene based anion exchange composite membranes with plasticizers and method for preparing the same

본 발명은 화학식 1로 표시되는 4 급 암모늄기가 도입된 비닐벤질계-스티렌계 공중합체 및 가소제를 포함하여 구성되는 음이온교환 복합막을 제공한다. 본 발명의 4 급 암모늄기가 도입된 비닐벤질계-스티렌계 공중합체 및 가소제를 포함하여 구성되는 음이온교환 복합막은 전기 저항이 낮으면서 이온교환능력, 기계적 물성, 화학적 물성 및 가공성이 향상될 뿐만 아니라 이온교환능력 및 이온전도도의 조절이 매우 용이하고, 종래의 음이온교환 복합막에 비해 이온전도도가 우수한 효과가 있다. 또한, 종래의 음이온교환 복합막에 비해 제조가 용이하고, 가격이 저렴한 효과가 있다. The present invention provides an anion exchange composite membrane comprising a quaternary ammonium group-introduced vinylbenzene-styrenic copolymer represented by the general formula (1) and a plasticizer. The anion exchange composite membrane comprising the quaternary ammonium group-introduced vinylbenzyl system-styrenic copolymer and the plasticizer of the present invention has improved ion exchange capacity, mechanical properties, chemical properties and processability while having low electrical resistance, Exchange ability and ionic conductivity are very easy to control and ionic conductivity is superior to that of the conventional anion exchange composite membrane. In addition, compared with the conventional anion-exchange composite membrane, it is easy to manufacture and has a low cost.

Filtration apparatus, purification apparatus, and manufacturing method of a chemical solution

우수한 결함 억제 성능을 갖는 약액을 제조 가능한 여과 장치의 제공을 과제로 한다. 또, 정제 장치, 및 약액의 제조 방법의 제공도 과제로 한다. 여과 장치는, 유입부와, 유출부와, 필터 A와, 필터 A와는 상이한 적어도 1개의 필터 B와 필터 A 및 필터 B가 직렬로 배치된 유입부로부터 유출부에 이르는 유통로를 갖는, 피정제액을 정제하여 약액을 얻기 위한 여과 장치이며, 필터 A는, 초고분자량 폴리에틸렌제의 다공성막과, 다공성막의 표면의 적어도 일부를 덮도록 배치된 수지층을 갖고, 수지층은, 중성기 또는 이온 교환기를 갖는 수지를 포함한다. An object of the present invention is to provide a filtration device capable of producing a chemical solution having excellent defect suppression performance. Moreover, provision of a purification apparatus and the manufacturing method of a chemical|medical solution is also made into a subject. The filtration device has an inlet, an outlet, a filter A, at least one filter B different from the filter A, and a flow path from an inlet to an outlet in which the filter A and the filter B are arranged in series, A filtration device for obtaining a chemical solution by purifying resins having

SPRAY DRIED SIALLYLACTOSE

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2020 119 953 A (51) МПК A23P 10/40 (2016.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2020119953, 07.12.2018 (71) Заявитель(и): ЙЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ (DE) Приоритет(ы): (30) Конвенционный приоритет: 08.12.2017 EP 17206124.4; 08.12.2017 EP 17206159.0; 08.12.2017 EP 17206223.4; 11.12.2017 EP 17206414.9; 08.02.2018 EP 18155669.7 (72) Автор(ы): ЙЕННЕВАЙН, Штефан (DE) R U (43) Дата публикации заявки: 10.01.2022 Бюл. № 1 2 0 2 0 1 1 9 9 5 3 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 08.07.2020 (86) Заявка PCT: EP 2018/083973 (07.12.2018) (87) Публикация заявки PCT: R U Адрес для переписки: 197101, Санкт-Петербург, а/я 128, "АРСПАТЕНТ", М.В. Хмара (54) ВЫСУШЕННАЯ РАСПЫЛЕНИЕМ СИАЛИЛЛАКТОЗА (57) Формула изобретения 1. Высушенный распылением порошок, по существу, состоящий из 3'-сиалиллактозы (3'-SL) и/или 6'-сиалиллактозы (6'-SL), которая была получена посредством микробной ферментации. 2. Высушенный распылением порошок по п. 1, где указанный высушенный распылением порошок содержит по меньшей мере 80 мас.%, по меньшей мере 85 мас.%, по меньшей мере 90 мас.%, по меньшей мере 93 мас.%, по меньшей мере 95 мас.% или по меньшей мере 98 мас.% 3'-SL и/или 6'-SL. 3. Высушенный распылением порошок по п. 1 или 2, в котором 3'-SL и/или 6'-SL находится в аморфной форме. 4. Высушенный распылением порошок по любому из пп. 1-3, где указанный высушенный распылением порошок содержит 15 мас.% воды или менее, предпочтительно 10 мас.% воды или менее, более предпочтительно 7 мас.% воды или менее, наиболее предпочтительно 5 мас.% воды или менее. 5. Высушенный распылением порошок по любому из пп. 1-4, где указанный высушенный распылением порошок не содержит генетически модифицированных микроорганизмов и молекул нуклеиновых кислот, происходящих из генетически Стр.: 1 A 2 0 2 0 1 1 9 9 5 3 A WO 2019/110803 (13.06.2019) A 2 0 2 0 1 1 9 9 5 3 A R U 2 0 2 0 1 1 9 9 5 3 Стр.: 2 R U ...

SPRAY DRIED TETRASACCHARIDES

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2020 119 946 A (51) МПК A23P 10/40 (2016.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2020119946, 07.12.2018 (71) Заявитель(и): ЙЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ (DE) Приоритет(ы): (30) Конвенционный приоритет: 08.12.2017 EP 17206124.4; 08.12.2017 EP 17206159.0; 08.12.2017 EP 17206223.4; 11.12.2017 EP 17206414.9; 08.02.2018 EP 18155669.7 (72) Автор(ы): ЙЕННЕВАЙН, Штефан (DE) R U (43) Дата публикации заявки: 10.01.2022 Бюл. № 1 2 0 2 0 1 1 9 9 4 6 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 08.07.2020 (86) Заявка PCT: EP 2018/083974 (07.12.2018) (87) Публикация заявки PCT: R U Адрес для переписки: 197101, Санкт-Петербург, а/я 128, "АРСПАТЕНТ", М.В. Хмара (54) ВЫСУШЕННЫЕ РАСПЫЛЕНИЕМ ТЕТРАСАХАРИДЫ (57) Формула изобретения 1. Высушенный распылением порошок, по существу состоящий из лакто-N-тетраозы (LNT) и/или лакто-N-неотетраозы (LNnT), которая была получена посредством микробной ферментации. 2. Высушенный распылением порошок по п. 1, где указанный высушенный распылением порошок, содержит по меньшей мере 80 мас. %, по меньшей мере 85 мас. %, по меньшей мере 90 мас. %, по меньшей мере 93 мас. %, по меньшей мере 95 мас. % или по меньшей мере 98 мас. % LNT и/или LNnT. 3. Высушенный распылением порошок по п. 1 или 2, в котором LNT и/или LNnT находится в аморфной форме. 4. Высушенный распылением порошок по любому из пп. 1-3, где указанный высушенный распылением порошок содержит 15 мас. % воды или менее, предпочтительно 10 мас. % воды или менее, более предпочтительно 7 мас. % воды или менее, наиболее предпочтительно 5 мас. % воды или менее. 5. Высушенный распылением порошок по любому из пп. 1-4, где указанный высушенный распылением порошок не содержит генетически модифицированных микроорганизмов и молекул нуклеиновых кислот, происходящих из генетически Стр.: 1 A 2 0 2 0 1 1 9 9 4 6 A WO 2019/110804 (13.06.2019) A 2 0 2 0 1 1 9 9 4 6 A R U 2 0 2 0 1 1 9 9 4 6 Стр.: 2 R ...

Extraction of lithium from acidic solution

FIELD: chemistry. SUBSTANCE: invention relates to extraction of lithium from lithium-containing material. Method includes the following: mixing lithium-containing material, which includes lithium-ion cell or battery, or lithium-containing mineral deposit in acid solution with pH of about 2.5 or less to form acid solution of lithium, wherein mixing is carried out at a temperature of about 10 °C to about 100 °C, and the acidic lithium solution includes an acid solution with a pH of about 2.5 or less, lithium and at least one or more components: acid solution, soluble organic substances, soluble metals and suspended solids; lithium acidic solution is fed onto membrane of preliminary ultra-filtration treatment to retain bulk of suspended solids and filtering acidic lithium solution penetration, including at least one or several components: acid solution with pH of about 2.5 or less, lithium, soluble organic substances and soluble metals; feeding a filtered lithium acid solution onto a nanofiltration membrane to form a retentate and a permeate; nanofiltration retentate includes soluble organic substances and/or soluble metals, and nanofiltration permeate forms a filtered acid and lithium solution containing an acid solution with pH of about 2.5 or less and lithium; feeding a filtered acid solution with a pH of about 2.5 or less and lithium on a reverse osmosis membrane to form a retentate and a permeate, the reverse osmosis retentate comprising lithium, and the reverse osmosis permeate comprising an acid solution with a pH of about 2.5 or less; and extracting lithium salts from reverse osmosis retentate to form recovered lithium and, optionally, returning the reverse osmosis permeate to the mixing step. EFFECT: technical result of the invention consists in economical and effective extraction of lithium from lithium-containing material. 9 cl, 7 tbl, 8 ex, 2 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 739 764 C1 (51) МПК B01D 61/02 (2006.01) B01D 61/14 (2006.01) B01D 61/ ...

SPRAY DRIED 3-FUCOSYLACTOSE

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2020 119 944 A (51) МПК A23P 10/40 (2016.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2020119944, 07.12.2018 (71) Заявитель(и): ЙЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ (DE) Приоритет(ы): (30) Конвенционный приоритет: 08.12.2017 EP 17206124.4; 08.12.2017 EP 17206159.0; 08.12.2017 EP 17206223.4; 11.12.2017 EP 17206414.9; 08.02.2018 EP 18155669.7 (72) Автор(ы): ЙЕННЕВАЙН, Штефан (DE) R U (43) Дата публикации заявки: 10.01.2022 Бюл. № 1 2 0 2 0 1 1 9 9 4 4 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 08.07.2020 (86) Заявка PCT: EP 2018/083969 (07.12.2018) (87) Публикация заявки PCT: R U Адрес для переписки: 197101, Санкт-Петербург, а/я 128, "АРСПАТЕНТ", М.В. Хмара (54) ВЫСУШЕННАЯ РАСПЫЛЕНИЕМ 3-ФУКОЗИЛЛАКТОЗА (57) Формула изобретения 1. Высушенный распылением порошок, по существу, состоящий из 3-фукозиллактозы, полученной способом микробной ферментации. 2. Высушенный распылением порошок по п. 1, отличающийся тем, что указанный высушенный распылением порошок содержит по меньшей мере 80 мас.%, по меньшей мере 85 мас.%, по меньшей мере 90 мас.%, по меньшей мере 93 мас.%, по меньшей мере 95 мас.%, или по меньшей мере 98 мас.% . 3-фукозил-лактозы. 3. Высушенный распылением порошок по п. 1 или 2, в котором 3-фукозиллактоза присутствует в аморфной форме. 4. Высушенный распылением порошок по любому из пп. 1-3, отличающийся тем, что высушенный распылением порошок содержит 15 мас.%, воды или менее, предпочтительно – 10 мас.%, воды или менее, более предпочтительно – 7 мас.%, воды или менее, наиболее предпочтительно 5 мас.%, воды или менее. 5. Высушенный распылением порошок по любому из пп. 1-4, отличающийся тем, что указанный высушенный распылением порошок не содержит генетически модифицированных микроорганизмов и молекул нуклеиновых кислот, полученных из генетически измененных микроорганизмов. Стр.: 1 A 2 0 2 0 1 1 9 9 4 4 A WO 2019/110801 (13.06.2019) A 2 0 2 0 1 1 9 9 4 4 A R U ...

Method and system for manufacturing battery grade and high purity grade lithium hydroxide and lithium carbonate from high-purity lithium source

본 발명은 고-불순도 리튬원으로부터 배터리 등급 및 고순도 등급 리튬 하이드록사이드 및 리튬 카보네이트를 제조하기 위한 방법 및 시스템을 개시한다. 방법은 정련된 리튬 염 용액의 제조 단계, 배터리 등급 리튬 하이드록사이드의 제조 단계, 고순도 등급 리튬 하이드록사이드의 제조 단계, 고순도 등급 리튬 카보네이트의 제조 단계 및 배터리 등급 리튬 카보네이트의 제조 단계를 포함한다. 시스템은 제조 순서에 따라 차례로 배열된, 정련된 리튬 염 용액 제조 하위시스템, 배터리 등급 리튬 하이드록사이드 제조 하위시스템, 고순도 등급 리튬 하이드록사이드 제조 하위시스템, 고순도 등급 리튬 카보네이트 제조 하위시스템 및 배터리 등급 리튬 카보네이트 제조 하위시스템을 포함한다. 리튬 함량, 불순물 분류 및 불순물 함량이 다양한 고-불순도 리튬원을 처리하기 위해, 본 발명은 고-불순도 리튬원의 품질 변동에 적응하고 배터리 등급 및 고순도 등급 리튬 하이드록사이드 및 리튬 카보네이트 산물의 제조를 위한 품질 요건에 부합하는 물리적 및 화학적 처리 방법의 차별화된 조합을 제안한다. 기존 제조 공정 및 기술 대비, 본 발명의 방법은 널리 적응 가능하며, 대부분의 부산물이 재활용 가능하고, 공정이 경제적이고 환경 친화적이다.

Patent RU2020119954A3

ВУ’? 2020119954” АЗ Дата публикации: 05.04.2022 Форма № 18 ИЗ, ПМ-2011 Федеральная служба по интеллектуальной собственности Федеральное государственное бюджетное учреждение 5 «Федеральный институт промышленной собственности» (ФИПС) ОТЧЕТ О ПОИСКЕ 1. . ИДЕНТИФИКАЦИЯ ЗАЯВКИ Регистрационный номер Дата подачи 2020119954/10(033876) 07.12.2018 РСТ/ЕР2018/083968 07.12.2018 Приоритет установлен по дате: [ ] подачи заявки [ ] поступления дополнительных материалов от к ранее поданной заявке № [ ] приоритета по первоначальной заявке № из которой данная заявка выделена [ ] подачи первоначальной заявки № из которой данная заявка выделена [ ] подачи ранее поданной заявки № [Х] подачи первой(ых) заявки(ок) в государстве-участнике Парижской конвенции (31) Номер первой(ых) заявки(ок) (32) Дата подачи первой(ых) заявки(ок) (33) Код страны 1. 17206124.4 08.12.2017 ЕР 2. 17206159.0 08.12.2017 ЕР 3. 17206223.4 08.12.2017 ЕР 4. 17206414.9 11.12.2017 ЕР 5. 18155669.7 08.02.2018 ЕР Название изобретения (полезной модели): [Х] - как заявлено; [ ] - уточненное (см. Примечания) ВЫСУШЕННАЯ РАСПЫЛЕНИЕМ СМЕСЬ ОЛИГОСАХАРИДОВ ГРУДНОГО МОЛОКА Заявитель: ИЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ, ОЕ 2. ЕДИНСТВО ИЗОБРЕТЕНИЯ [Х] соблюдено [ ] не соблюдено. Пояснения: см. Примечания 3. ФОРМУЛА ИЗОБРЕТЕНИЯ: [Х] приняты во внимание все пункты (см. Примечания) [ ] приняты во внимание следующие пункты: [ ] принята во внимание измененная формула изобретения (см. Примечания) 4. КЛАССИФИКАЦИЯ ОБЪЕКТА ИЗОБРЕТЕНИЯ (ПОЛЕЗНОЙ МОДЕЛИ) (Указываются индексы МПК и индикатор текущей версии) А231. 33/10 (2016.01) 5. ОБЛАСТЬ ПОИСКА 5.1 Проверенный минимум документации РСТ (указывается индексами МПК) А23Т, 33/19 А23ЗР 10/40 5.2 Другая проверенная документация в той мере, в какой она включена в поисковые подборки: 5.3 Электронные базы данных, использованные при поиске (название базы, и если, возможно, поисковые термины): Езрасепе Соозе, Рабеагсв, Уапдех 6. ДОКУМЕНТЫ, ОТНОСЯЩИЕСЯ К ПРЕДМЕТУ ПОИСКА Кате- Наименование документа с ...

Method for purifying caprolactam hydrolysate

本发明公开了一种己内酰胺水解液的纯化方法。将己内酰胺水解液通入双极膜电渗析装置进料室，水解液中的氯离子或钠离子在直流电场的作用下，进入酸室或碱室，最终得到去除，实现纯化。该方法能够避免酸或碱的使用，减少化学药剂的使用，实现了酸或碱的再生及循环利用，是一种清洁生产工艺。

Method and system for producing battery grade and high purity grade lithium hydroxide and lithium carbonate from a high-impure lithium source

본 발명은 고-불순도 리튬원으로부터 배터리 등급 및 고순도 등급 리튬 하이드록사이드 및 리튬 카보네이트를 제조하기 위한 방법 및 시스템을 개시한다. 방법은 정련된 리튬 염 용액의 제조 단계, 배터리 등급 리튬 하이드록사이드의 제조 단계, 고순도 등급 리튬 하이드록사이드의 제조 단계, 고순도 등급 리튬 카보네이트의 제조 단계 및 배터리 등급 리튬 카보네이트의 제조 단계를 포함한다. 시스템은 제조 순서에 따라 차례로 배열된, 정련된 리튬 염 용액 제조 하위시스템, 배터리 등급 리튬 하이드록사이드 제조 하위시스템, 고순도 등급 리튬 하이드록사이드 제조 하위시스템, 고순도 등급 리튬 카보네이트 제조 하위시스템 및 배터리 등급 리튬 카보네이트 제조 하위시스템을 포함한다. 리튬 함량, 불순물 분류 및 불순물 함량이 다양한 고-불순도 리튬원을 처리하기 위해, 본 발명은 고-불순도 리튬원의 품질 변동에 적응하고 배터리 등급 및 고순도 등급 리튬 하이드록사이드 및 리튬 카보네이트 산물의 제조를 위한 품질 요건에 부합하는 물리적 및 화학적 처리 방법의 차별화된 조합을 제안한다. 기존 제조 공정 및 기술 대비, 본 발명의 방법은 널리 적응 가능하며, 대부분의 부산물이 재활용 가능하고, 공정이 경제적이고 환경 친화적이다. The present invention discloses a method and system for producing battery grade and high purity grade lithium hydroxide and lithium carbonate from a high-impure lithium source. The method includes preparing a refined lithium salt solution, preparing a battery grade lithium hydroxide, preparing a high purity grade lithium hydroxide, preparing a high purity grade lithium carbonate, and preparing a battery grade lithium carbonate. The system consists of a refined lithium salt solution manufacturing subsystem, a battery grade lithium hydroxide manufacturing subsystem, a high purity grade lithium hydroxide manufacturing subsystem, a high purity grade lithium carbonate manufacturing subsystem, and a battery grade lithium, arranged in sequence according to the manufacturing sequence. Includes a carbonate manufacturing subsystem. In order to treat high-impurity lithium sources having a variety of lithium content, impurity classification and impurity content, the present invention adapts to the quality fluctuations of high-impurity lithium sources, and provides battery grade and high purity grade lithium hydroxide and lithium carbonate products. We propose a differentiated combination of physical and chemical treatment methods that meet the quality requirements for manufacturing. Compared to existing manufacturing processes and technologies, the method of the ...

Chemical liquid manufacturing apparatus

本发明提供一种包括第一系统及第二系统的化学液制造设备。第一系统包括选自第一过滤器、第一离子交换膜及第一离子吸附膜中的至少一个第一过滤介质，其中第一系统被配置成对材料处理至少一次。第二系统包括选自第二过滤器、第二离子交换膜及第二离子吸附膜中的至少一个第二过滤介质，其中第二系统被配置用于再循环并对所述材料处理至少两次。

Method of making a composite membrane

A method of making a composite membrane with ion exchange properties includes, in an exemplary embodiment, forming a porous membrane from a first material, dissolving a coating material in a fluid at supercritical conditions, and exposing the porous membrane to the coating material dissolved in the supercritical fluid. The method also includes precipitating a uniform coating of the coating material onto an exterior surface of the porous membrane by changing the supercritical conditions of the fluid to a non-supercritical condition, and applying an ion exchange material to the coated porous membrane so that the ion exchange material is in intimate contact with substantially all of the coated surfaces of the porous membrane.

Patent RU2020119951A3

`7ВУ’” 2020119951” АЗ Дата публикации: 28.04.2022 Форма № 18 ИЗ,ПМ-2011 Федеральная служба по интеллектуальной собственности Федеральное государственное бюджетное учреждение 5 «Федеральный институт промышленной собственности» (ФИПС) ОТЧЕТ О ПОИСКЕ 1. . ИДЕНТИФИКАЦИЯ ЗАЯВКИ Регистрационный номер Дата подачи 2020119951/10(033873) 07.12.2018 РСТ/ЕР2018/083978 07.12.2018 Приоритет установлен по дате: [ ] подачи заявки [ ] поступления дополнительных материалов от к ранее поданной заявке № [ ] приоритета по первоначальной заявке № из которой данная заявка выделена [ ] подачи первоначальной заявки № из которой данная заявка выделена [ ] подачи ранее поданной заявки № [Х] подачи первой(ых) заявки(ок) в государстве-участнике Парижской конвенции (31) Номер первой(ых) заявки(ок) (32) Дата подачи первой(ых) заявки(ок) (33) Код страны 1. 17206124.4 08.12.2017 ЕР 2. 17206159.0 08.12.2017 ЕР 3. 17206223.4 08.12.2017 ЕР 4. 17206414.9 11.12.2017 ЕР 5. 18155669.7 08.02.2018 ЕР Название изобретения (полезной модели): [Х] - как заявлено; [ ] - уточненное (см. Примечания) ВЫСУШЕННАЯ РАСПЫЛЕНИЕМ ЛАКТО-М-ФУКОПЕНТАОЗА Заявитель: ИЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ, ОЕ 2. ЕДИНСТВО ИЗОБРЕТЕНИЯ [Х] соблюдено [ ] не соблюдено. Пояснения: см. Примечания 3. ФОРМУЛА ИЗОБРЕТЕНИЯ: [Х] приняты во внимание все пункты (см. Примечания) [ ] приняты во внимание следующие пункты: [ ] принята во внимание измененная формула изобретения (см. Примечания) 4. КЛАССИФИКАЦИЯ ОБЪЕКТА ИЗОБРЕТЕНИЯ (ПОЛЕЗНОЙ МОДЕЛИ) (Указываются индексы МПК и индикатор текущей версии) А23Р 10/40 (2016.01) 5. ОБЛАСТЬ ПОИСКА 5.1 Проверенный минимум документации РСТ (указывается индексами МПК) А23Р; А23133 5.2 Другая проверенная документация в той мере, в какой она включена в поисковые подборки: 5.3 Электронные базы данных, использованные при поиске (название базы, и если, возможно, поисковые термины): Е-Глбгагу, Езрасепе, РаЗеагсв, РАТЕМТЗСОРЕ, КУРТО, Соозе, Соозе эсво]аг, РиБМеа, ОРТО, Заепсе) шест 6. ДОКУМЕНТЫ, ОТНОСЯЩИЕСЯ К ПРЕДМЕТУ ПОИСКА ...

METHOD FOR WASTE WATER TREATMENT FORMED WHEN PRODUCING HALOGENED POLYMER

1. Способ обработки сточных вод, образующихся при получении галогенированного полимера, который включает стадию полимеризации, по меньшей мере, одного галогенированного мономера, осуществляемую в водной среде, из которой затем выделяют непрореагировавший мономер и полученный полимер, при этом упомянутый способ включает:- стадию физико-химической обработки, по меньшей мере, одной части упомянутых сточных вод, при этом, по меньшей мере, одна часть которых предварительно подвергается первой очистке с использованием, по меньшей мере, одной физической обработки;- стадию заключительной очистки, содержащую биохимическую фильтрацию, осуществляемую с применением мембранного биореактора, по меньшей мере, одной части воды, образующейся после физико-химической обработки.2. Способ по п. 1, отличающийся тем, что галогенированный полимер представляет собой полимер винилхлорида.3. Способ по п. 1, отличающийся тем, что стадию полимеризации осуществляют в водной суспензии.4. Способ по п. 1, отличающийся тем, что физико-химическая обработка содержит перемешивание сточных вод, а также процедуру осветления в сочетании с применением коагулянтов и флоккулянтов.5. Способ по п. 1, отличающийся тем, что первая очистка, которой подвергается, по меньшей мере, одна часть сточных вод, включает фильтрацию.6. Способ по п. 5, отличающийся тем, что фильтрация представляет собой микрофильтрацию или ультрафильтрацию.7. Способ по п. 5 или 6, отличающийся тем, что в добавление к фильтрации и после нее осуществляют стадию химической очистки с использованием ионного обмена или стадию физической очистки с использованием обратного осмоса.8. Способ по любому РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК C02F 9/00 (13) 2013 125 564 A (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2013125564/05, 28.10.2011 (71) Заявитель(и): СОЛВЕЙ СА (BE) Приоритет(ы): (30) Конвенционный приоритет: 04.11.2010 FR 1059081 (85) Дата начала рассмотрения заявки PCT на ...

Method for efficiently extracting and separating high-purity tetrodotoxin from globefish viscera

本发明公开一种高效的从河豚内脏提取和分离制备高纯度河豚毒素（tetrodotoxin,简称TTX）的方法；其包括以下步骤：将干净的河豚内脏加酸性醇匀浆、加入一定量的助流动剂搅拌均匀后，按柱层析的装柱方法将材料装入层析柱中；用同一酸性醇将河豚内脏中的TTX完全洗脱出来，收集洗脱液为TTX提取液；提取液减压浓缩至水相，得到TTX提取浓缩液；TTX水溶液用离子交换树脂柱层析分离，收集含TTX高的洗脱液，用纳滤膜浓缩或减压蒸干，得到TTX粗品；TTX粗品通过溶剂沉淀和结晶，得到纯度达于98%的TTX；本发明的制备TTX的方法和所用设备简单，TTX提取和分离纯化的得率高、制备成本低，适合TTX的规模化生产；同时该方法使用的有机溶剂可全部回收重复使用，无有害溶剂和废弃物排放，是理想的安全环保的制备TTX方法。

Apparatus and methods for fractionation of biological products

使用单个装置中的切向流过滤子单元与吸附子单元的组合来纯化生物分子的方法和装置，其中所述子单元可以被独立地或串联地操作，并且其中所述装置和方法适合于在与色谱方法所需条件不同的大范围的形式中使用，例如在未经过预先缓冲液平衡的情况下使用吸附子单元执行处理步骤以纯化受污染的样品中的生物分子。

Filtration equipment, purification equipment, and method for manufacturing chemicals

優れた欠陥抑制性能を有する薬液を製造可能なろ過装置の提供を課題とする。また、精製装置、及び、薬液の製造方法の提供も課題とする。ろ過装置は、流入部と、流出部と、フィルタＡと、フィルタＡとは異なる少なくとも１つのフィルタＢと、フィルタＡ及びフィルタＢが直列に配置された流入部から流出部にいたる流通路とを有する、被精製液を精製して薬液を得るためのろ過装置であって、フィルタＡは、超高分子量ポリエチレン製の多孔性膜と、多孔性膜の表面の少なくとも一部を覆うように配置された樹脂層とを有し、樹脂層は、中性基又はイオン交換基を樹脂を含む。 An object of the present invention is to provide a filtration device capable of producing a chemical solution having excellent defect suppression performance. Another issue is to provide a purification apparatus and a method for producing a chemical solution. The filtration device includes an inflow portion, an outflow portion, a filter A, at least one filter B different from the filter A, and an inflow passage from the inflow portion to the outflow portion in which the filter A and the filter B are arranged in series. It is a filtration device for purifying a liquid to be purified to obtain a chemical liquid, and the filter A is arranged so as to cover at least a part of a porous membrane made of ultra-high molecular weight polyethylene and a surface of the porous membrane. The resin layer contains a neutral group or an ion exchange group.

Ultrapure water production apparatus

本发明提供一种可稳定地制造微粒经高度去除的高水质的超纯水的超纯水制造装置。本发明的超纯水制造装置，其具有从一次纯水制造超纯水的次系统，在该次系统的最终段中设置有膜装置，其特征在于，该膜装置是以串联的方式设置有多段，并且，第1段的膜装置为UF膜装置、MF膜装置或RO膜装置，最终段的膜装置为UF膜装置或未经离子交换基修饰的MF膜装置。

Complex filter and filter system comprising the same

본 발명은 복합 필터 및 이를 포함하는 필터 시스템에 관한 것이다. 일 측면에 따른 복합 필터는 카본 블럭 필터; 및 상기 카본 블럭 필터의 외주면을 감싸고, 적어도 일부가 양전하를 띠는 이온흡착부를 포함하고, 원수는 상기 이온흡착부를 통과한 후 상기 카본 블록 필터를 통과하고, 상기 원수에 포함된 음전하 입자는 상기 이온흡착부에 흡착되는 것을 특징으로 한다. 일 측면에 따른 필터 시스템은 카본 블럭 필터 및 상기 카본 블럭 필터의 외주면을 감싸는 이온흡착부가 구비되는 복합 필터; 및 물에 존재하는 바이러스를 필터링하기 위한 기공이 형성되는 중공사막 필터를 포함하고, 원수는 상기 이온흡착부를 통과한 후 상기 카본 블록 필터를 통과하고, 상기 이온흡착부는, 물에 존재하는 음전하 입자를 이온흡착하도록 적어도 일부가 양전하를 띠는 것을 특징으로 한다.

Patent RU2020119946A3

``” ВУ” 2020119946” АЗ Дата публикации: 28.04.2022 Форма № 18 ИЗ,ПМ-2011 Федеральная служба по интеллектуальной собственности Федеральное государственное бюджетное учреждение 5 «Федеральный институт промышленной собственности» (ФИПС) ОТЧЕТ О ПОИСКЕ 1. . ИДЕНТИФИКАЦИЯ ЗАЯВКИ Регистрационный номер Дата подачи 2020119946/10(033868) 07.12.2018 РСТ/ЕР2018/083974 07.12.2018 Приоритет установлен по дате: [ ] подачи заявки [ ] поступления дополнительных материалов от к ранее поданной заявке № [ ] приоритета по первоначальной заявке № из которой данная заявка выделена [ ] подачи первоначальной заявки № из которой данная заявка выделена [ ] подачи ранее поданной заявки № [Х] подачи первой(ых) заявки(ок) в государстве-участнике Парижской конвенции (31) Номер первой(ых) заявки(ок) (32) Дата подачи первой(ых) заявки(ок) (33) Код страны 1. 17206124.4 08.12.2017 ЕР 2. 17206159.0 08.12.2017 ЕР 3. 17206223.4 08.12.2017 ЕР 4. 17206414.9 11.12.2017 ЕР 5. 18155669.7 08.02.2018 ЕР Название изобретения (полезной модели): [Х] - как заявлено; [ ] - уточненное (см. Примечания) ВЫСУШЕННЫЕ РАСПЫЛЕНИЕМ ТЕТРАСАХАРИДЫ Заявитель: ИЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ, ОЕ 2. ЕДИНСТВО ИЗОБРЕТЕНИЯ [Х] соблюдено [ ] не соблюдено. Пояснения: см. Примечания 3. ФОРМУЛА ИЗОБРЕТЕНИЯ: [Х] приняты во внимание все пункты (см. Примечания) [ ] приняты во внимание следующие пункты: [ ] принята во внимание измененная формула изобретения (см. Примечания) 4. КЛАССИФИКАЦИЯ ОБЪЕКТА ИЗОБРЕТЕНИЯ (ПОЛЕЗНОЙ МОДЕЛИ) (Указываются индексы МПК и индикатор текущей версии) А23Р 10/40 (2016.01) 5. ОБЛАСТЬ ПОИСКА 5.1 Проверенный минимум документации РСТ (указывается индексами МПК) А23Р; А23133 5.2 Другая проверенная документация в той мере, в какой она включена в поисковые подборки: 5.3 Электронные базы данных, использованные при поиске (название базы, и если, возможно, поисковые термины): Е-Глбгагу, Езрасепе, РаЗеагсв, РАТЕМТЗСОРЕ, КУРТО, Соозе, Соозе эсво]аг, РиБМеа, ОРТО, Заепсе) шест 6. ДОКУМЕНТЫ, ОТНОСЯЩИЕСЯ К ПРЕДМЕТУ ПОИСКА Кате- ...

Patent RU2020119953A3

ВУ“? 2020119953” АЗ Дата публикации: 05.04.2022 Форма № 18 ИЗ,ПМ-2011 Федеральная служба по интеллектуальной собственности Федеральное государственное бюджетное учреждение 5 «Федеральный институт промышленной собственности» (ФИПС) ОТЧЕТ О ПОИСКЕ 1. . ИДЕНТИФИКАЦИЯ ЗАЯВКИ Регистрационный номер Дата подачи 2020119953/10(033875) 07.12.2018 РСТ/ЕР2018/083973 07.12.2018 Приоритет установлен по дате: [ ] подачи заявки [ ] поступления дополнительных материалов от к ранее поданной заявке № [ ] приоритета по первоначальной заявке № из которой данная заявка выделена [ ] подачи первоначальной заявки № из которой данная заявка выделена [ ] подачи ранее поданной заявки № [Х] подачи первой(ых) заявки(ок) в государстве-участнике Парижской конвенции (31) Номер первой(ых) заявки(ок) (32) Дата подачи первой(ых) заявки(ок) (33) Код страны 1. 17206124.4 08.12.2017 ЕР 2. 17206159.0 08.12.2017 ЕР 3. 17206223.4 08.12.2017 ЕР 4. 17206414.9 11.12.2017 ЕР 5. 18155669.7 08.02.2018 ЕР Название изобретения (полезной модели): [Х] - как заявлено; [ ] - уточненное (см. Примечания) ВЫСУШЕННАЯ РАСПЫЛЕНИЕМ СИАЛИЛЛАКТОЗА Заявитель: ИЕННЕВАЙН БИОТЕХНОЛОГИ ГМБХ, ОЕ 2. ЕДИНСТВО ИЗОБРЕТЕНИЯ [Х] соблюдено [ ] не соблюдено. Пояснения: см. Примечания 3. ФОРМУЛА ИЗОБРЕТЕНИЯ: [Х] приняты во внимание все пункты (см. Примечания) [ ] приняты во внимание следующие пункты: [ ] принята во внимание измененная формула изобретения (см. Примечания) 4. КЛАССИФИКАЦИЯ ОБЪЕКТА ИЗОБРЕТЕНИЯ (ПОЛЕЗНОЙ МОДЕЛИ) (Указываются индексы МПК и индикатор текущей версии) А23Р 10/40 (2016.01) 5. ОБЛАСТЬ ПОИСКА 5.1 Проверенный минимум документации РСТ (указывается индексами МПК) А23Р 10/40, А2ЗГ, 33/00 5.2 Другая проверенная документация в той мере, в какой она включена в поисковые подборки: 5.3 Электронные базы данных, использованные при поиске (название базы, и если, возможно, поисковые термины): Езрасепе, Соозе, Рабеагсв, Уап4дех 6. ДОКУМЕНТЫ, ОТНОСЯЩИЕСЯ К ПРЕДМЕТУ ПОИСКА Кате- Наименование документа с указанием (где необходимо) ...

RECOVERY OF GRAPHITE FROM LITHIUM-ION CELLS OR BATTERIES

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2020 141 390 A (51) МПК B01D 61/02 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2020141390, 17.07.2018 (71) Заявитель(и): ЛИН, Ларри (US) Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): ЛИН, Ларри (US) (43) Дата публикации заявки: 28.12.2020 Бюл. № 1 R U (57) Формула изобретения 1. Способ извлечения графита из литий-ионных ячеек или батарей, который включает в себя следующее: разбирают литий-ионную ячейку или батарею для отделения анода от катода, получая разобранную литий-ионную ячейку или батарею; перемешивают разобранную литий-ионную ячейку или батарею с кислотой при температуре от около 10°C примерно до 100°C с получением кислого раствора, содержащего графит, литий и необязательно растворимые органические вещества, растворимые металлы и взвешенные твёрдые вещества; причем кислота имеет рН около 2,5 и менее и включает соляную кислоту, серную кислоту, азотную кислоту, уксусную кислоту, лимонную кислоту и их сочетания и выделяют графит из кислого раствора. 2. Способ извлечения графита по п. 1, в котором разборка включает удаление оболочки, окружающей анод, катода и электролита литий-ионной ячейки или батареи. 3. Способ извлечения графита по п. 1, в котором литий-ионная ячейка или батарея представляет собой отработанную литий-ионную ячейку или батарею. 4. Способ извлечения графита по п. 1, в котором кислота включает соляную кислоту, серную кислоту, азотную кислоту или их сочетания и концентрация кислоты в водном растворе составляет от около 0,5 до около 30 мас.% и кислота имеет рН около 1 или менее. 5. Способ извлечения графита по п. 1, в котором перемешивание проводят от около 1 мин. до около 120 мин. 6. Способ извлечения графита по п. 1, в котором перемешивание проводят при температуре от около 50°C до около 70°C. 7. Способ извлечения графита по п. 1, который дополнительно включает пропускание Стр.: 1 A 2 0 2 0 1 4 1 3 9 0 A (54) ИЗВЛЕЧЕНИЕ ГРАФИТА ИЗ ...

Waste water cleaning system, washing device, and ink jet printer system

Problem To reduce the frequency of the removal of residue and suppress a reduction in the filtering efficiency of an RO membrane and damage to the RO membrane. Means for Resolution A wastewater purifying system includes: a wastewater tank 21 which stores wastewater discharged from a washing device 13 which washes a textile T subjected to printing by using an inkjet printer 11; an enzyme/microorganism feeding device 26 which feeds an enzyme and a microorganism which degrade a dye into the wastewater tank 21; a pH adjusting agent feeding device 27 which feeds a pH adjusting agent into the wastewater tank 21; a stirring device 28 which stirs the wastewater in the wastewater tank 21; a heat insulating device 29 which keeps the wastewater tank 21 warm; a filtering device 22 which filters the wastewater by cross-flow filtering using an RO membrane; a pump 23 which pumps the wastewater to the filtering device 22 from the wastewater tank 21; an ion removing device 24 which removes ions by bringing the filtered water into contact with an ion exchange resin; and a decoloring device 25 which decolors the filtered water by bringing the filtered water into contact with activated carbon.

Desalination of liquid by electro dialyses