УСТРОЙСТВО РАЗДЕЛЕНИЯ ВОЗДУХА И ХОЛОДИЛЬНОЕ И МОРОЗИЛЬНОЕ УСТРОЙСТВО

Настоящее изобретение относится к области технологии разделения газа, в частности к устройству разделения воздуха и холодильному и морозильному устройству. Устройство разделения воздуха содержит опорную раму, на которой образованы опорная поверхность с каналом и камера для сбора обогащенного газа, сообщающаяся с каналом, и мембрану для разделения воздуха, наложенную на опорную поверхность и приспособленную для обеспечения поступления в камеру для сбора обогащенного газа. Опорная рама содержит отверстие для удаления воздуха, сообщающееся с камерой для сбора обогащенного газа, раму, в которой образована приемная камера с отверстием и множество ребер, размещенных с интервалами в отверстии приемной камеры, при этом внешние боковые поверхности ребер образуют опорную поверхность, зазор между двумя смежными ребрами образует канал, полость, расположенная с внутренних сторон множества ребер, приемной камеры образует камеру для сбора обогащенного газа, а ось отверстия для удаления воздуха и множество ...

КАПСУЛА С ФИЛЬТРОМ ДЛЯ ПРИГОТОВЛЕНИЯ ПИЩЕВОГО ПРОДУКТА И СПОСОБ ПРИГОТОВЛЕНИЯ ПИЩЕВОГО ПРОДУКТА

... 1. Капсула для приготовления пищевого продукта в устройстве, приспособленном для подачи жидкости в капсулу, содержащая по меньшей мере один отсек (13) с пищевыми ингредиентами, смешиваемыми с подаваемой жидкостью для приготовления пищевого продукта, и фильтр, предназначенный для удаления содержащихся в жидкости загрязнений, характеризующаяся тем, что фильтр выполнен в виде фильтрующего приспособления (18), состоящего из фильтрующей мембраны (20) и выпускной стенки (23), на которую опирается фильтрующая мембрана, при этом в выпускной стенке имеется по меньшей мере одно выпускное отверстие (26) для жидкости, сообщающееся с указанным отсеком (13).2. Капсула по п.1, характеризующаяся тем, что выпускное отверстие (26) для жидкости аксиально смещено относительно фильтрующей поверхности фильтрующей мембраны (20).3. Капсула по п.1, характеризующаяся тем, что фильтрующая мембрана представляет собой микропористую мембрану.4. Капсула по п.1, характеризующаяся тем, что фильтрующее приспособление (18 ...

УСТРОЙСТВО ДЛЯ ОТДЕЛЕНИЯ ПЛАЗМЫ КРОВИ

... 1. Устройство (1) для забора крови (19) и отделения ее составных частей, таких как плазма, в качестве анализируемой жидкости (2), имеющее подводящее устройство (13) для забора крови (2), мембрану (15) для отделения от крови ее составных частей в качестве анализируемой жидкости (2), канал (3), в который анализируемая жидкость (2) поступает и по которому она движется под действием капиллярных сил, и питающее устройство для заполнения канала (3) анализируемой жидкостью (2) на его впускном или входном участке (18), отличающееся тем, что мембрана (15) и/или дно входного участка выполнены/выполнена, соответственно выполнено изогнутой, прежде всего выпуклой, формы и вершиной своей изогнутой части выступают/выступает в питающее устройство в направлении заполнения, при этом мембрана (15) в своей центральной части прилегает ко дну питающего устройства, вследствие чего выходящая с нижней стороны мембраны анализируемая жидкость непосредственно смачивает дно питающего устройства. ! 2. Устройство по ...

Vorrichtung zur Gewinnung von Sauerstoff

VERBUNDKONSTRUKTION UND METHODE ZU DEREN BILDUNG

PROCESS AND APPARATUS FOR FILTERING A SUSPENSION OF PARTICLES IN A LIQUID

Vorrichtung zum Abtrennen von Wasserstoff aus Gasgemischen

Allseitig abgeschlossene permselektive Fluessig-Membran

WASSERSTOFF-PERMEATIONSWAND, VERFAHREN ZUR HERSTELLUNG DERSELBEN UND DEREN VERWENDUNG.

VERFAHREN ZUR RÜCKGEWINNUNG VON FARBEN

Wasserstoff-Separator und Verfahren zu seiner Herstellung

Die Erfindung betrifft einen Wasserstoffseparator 22 mit einer dünnen wasserstoffdurchlässigen Folie 16 einer Dicke zwischen 3 und 15 micron. Die Folie 16 ist an eine Trägerstruktur 18 gebunden, die eine wellenförmige Oberfläche mit Kontaktbereichen 20, an denen die Folie 16 befestigt ist, aufweist. Die Folie 16 ist üblicherweise an die wellenförmige Oberfläche angepaßt. Die Folie 16 ist nur an den Kontaktbereichen 20 der Trägerstruktur 18 befestigt; wodurch sie sich in drei Richtungen bewegen kann, wenn sie expandiert und kontrahiert, während sie einem Wasserstoff-Ausgangsstrom ausgesetzt ist. Die Kontaktbereiche 20 sind im Vergleich zur Foliendicke relativ nah beabstandet und ermöglichen es der dünnen Folie 16, hohen Drücken zu widerstehen.

Ultra-filtration apparatus and method

... 962,167. Filters for liquids. TECHNICON INSTRUMENTS CORPORATION. Oct. 27, 1960 [Nov. 17, 1959], No. 36858/60. Heading B1D In a method of ultrafiltration, in which the filter comprises a semi-permeable membrane 20 of regenerated cellulose, of pore size about 5,000-10,000 Angstrom units, clamped between two grooved plates 22 which are fitted with nozzles 32 and form liquid passages, and a stream of liquid to be filtered is pumped to one of the passages simultaneously with a second stream of liquid to the other passage such that a proportion of the first stream is filtered into the second stream, the rate of filtration is controlled by the diameter of the outlet pipe 16 from the first passage, which is always less than that of the inlet pipe 14, the second stream leaving the plate 22 through outlet 46. Specifications 774,711 and 827,925 are referred to.

Filters and Filter Units

A filter unit comprises a plastics frame (10) into which a sheet of filter medium (19) is insert moulded. Portions of the frame form apertures (14) and other portions allow fluid access to and from the opposed surfaces of the filter medium (19) when the frame is covered by a flat surface. The frames also form portions of an integral capsule enclosing the medium. A number of such filter units (24) can be stacked together in various configurations so that the apertures (14) form inlets and outlets for fluid so that, in some configurations, fluid can be passed through the filter units in parallel while, in other configurations, fluid can be passed through filter units in succession. Filters of any convenient size can be produced by increasing the number of filter units (24) in a stack. The filters are bi-directional. The frames (10) can be of polypropylene connected to hydrophilic microporous nylon membrane by injection moulding, which has been found to give a filter unit that can be integrity ...

Flow control in tangential flow membrane filtration; pressure gauge

There is provided on the feed side of the membrane at least one thin channel 4 having a plurality of main flow channels 4a,4b,4c... connected by transitional regions 7ab,7bc... which cause an abrupt change in flow direction whereby polarisation and fouling of the membrane are reduced. The outlet 6 therefrom may have a flow restrictor 49 of reducing conical section with an outlet orifice of predetermined size to control pressure and flow speed. A pressure gauge 42 includes a spring-loaded piston 44 frictionally engaging the walls of a cylinder via an O-ring and having an inlet channel 45 of restricted size. This gauge is relatively insensitive to pressure fluctuation and is self-emptying on pressure release.

BAG-LIKE WATER PURIFICATION DEVICE

BAG-LIKE WATER PURIFICATION DEVICE

BAG-LIKE WATER PURIFICATION DEVICE

FILTER DEVICE WITH INTEGRATED CENTRIFUGAL SEPARATION

SYSTEM UND VERFAHREN ZUM BEARBEITEN VON BIOLOGISCHEN FLÜSSIGKEITEN

ONE-WAY OWNER FOR SHUNT CURRENT FILTRATION APPARATUSES

SCREW-TYPE CAP WITH A WARRANTY RING FOR A CONTAINER FOR THE ANNOUNCEMENT OF THE FIRST OPENING OF THE CONTAINER

VACUUM FILTER ASSEMBLY

DEVICE FOR COLLECTION AND TRANSMISSION OF PARTICLES AND PROCEDURE FOR THE PRODUCTION OF SUCH A DEVICE.

FILTRATION DEVICE FOR THE DISTANCE OF LEUKOCYTES

DEVICE FOR CONCENTRATING AND/OR CLEANING FROM MACROMOLECULES IN A SOLUTION AND PROCEDURES TO MANUFACTURING A SUCH DEVICE

BAG-LIKE FILTER

JIG AND DEVICE FOR FILTRATION

Filter tube, specially for microspheres

Micro-fluidic anti-microbial filter

An in-line blood filtration device

IMPROVEMENTS RELATING TO FILTERS

SEPARATING ASBESTOS FIBRE FROM ASBESTOS-BEARING MATERIAL

FILTER HOLDER

SHEET-FORM MEMBRANE SAMPLE PROBE, METHOD AND APPARATUS FOR FLUID CONCENTRATION ANALYSIS

A sheet form membrane probe, an apparatus and method, wherein the probe includes a probe body, a sheet-form membrane secured to the probe body and including an open surface exposed to the exterior of the probe; a channel formed between the probe body and the membrane through which a collector fluid can flow; an inlet port opening to the channel to conduct collector fluid to the channel; and an outlet port spaced from the inlet port such that the collector fluid passes through the channel from the inlet port to the outlet port in a flow direction substantially parallel to the membrane. The channel may be formed to provide broad surface contact of the collector fluid with the membrane. The membrane open surface may include an active area open to a sample fluid and open on an opposite side for contact with collector fluid flow in the channel. The active area may be large relative to the total membrane area to provide for an effective use of the expensive membrane material. Another probe includes ...

FILTERING UNIT

The invention concerns a filtering unit comprising a filter diaphragm , a backing surface disposed against the diaphragm, and passages through which the liquid to be filtered can be supplied on one side of the diaphragm and the liquid that has drained through the diaphragm can be removed from the opposite side of the diaphragm. As taught by the invention, the backing surface is provided with ridges lying side by side and with grooves, moving liquid in the direction parallel to the diaphragm , between them and which start in the central part of the surface in different directions and lead to the periphery of the surface, curving in such manner that the spacing of mutually adjacent ridges is substantially constant on the entire area of the backing surface. The backing surface will then to the filter diaphragm lend throughout uniform support. When the filtering unit has a backing surface of said kind on both sides of the filter diaphragm , the unit may be shaped to be a closed entity in which ...

METHOD OF REGENERATING A SEPARATION MEANS FOR A LIQUID MEDIUM CONTAINING UNDISSOLVED CONSTITUENTS AND A SEPARATION APPARATUS

A method of regenerating a dynamic membrane in a separation apparatus for a liquid medium containing undissolved constituents and a separation apparatus for separating the undissolved constituents from the liquid medium. The apparatus comprises: a housing which provides a chamber therein and which includes an inlet for liquid containing undissolved constituents, an outlet for a permeate stream and an outlet for a reject stream; a dynamic membrane positioned within said chamber, said dynamic membrane comprising a support matrix and a layer of particle material on said support matrix, said layer of particle material being exposed to said liquid containing undissolved constituents supplied to said chamber via said inlet. A rotatable rotor is located in said chamber, and includes a movable device thereon which can contact a deposit of undissolved constituents formed on said layer of particle material of said dynamic membrane only when the rotor is rotated in one direction of rotation so as ...

SOLVENT CLEANSING APPARATUS

SOLVENT CLEANSING APPARATUS An apparatus is disclosed for cleansing an aliphatic hydrocarbon solvent of an oil based contaminant. The apparatus includes a source of a contaminated solvent and an ultrafiltration filter having a semi-permeable membrane with a pore size selected to pass molecules of the solvent through the membrane and restrict passage through the membrane of molecules of the contaminant. A water cooled jacket is provided for maintaining the temperature of the solvent in the apparatus below a flash point. Pressure switches are provided for maintaining the pressure at the inlet of the ultrafiltration filter below a predetermined maximum to protect the filter. Concentrate of the ultrafiltration filter is recirculated to the source of the contaminated solvent.

METHOD OF DEWAXING A VEGETABLE OIL

This invention relates to a method of dewaxing a vegetable oil. More particularly, the present invention is concerned with a method of removing a wax from a vegetable oil by means of a porous membrane. The process of the present invention is useful not only for dewaxing a vegetable oil but also for removing a wax together with a phospholipid, a free fatty acid and water from a crude vegetable oil, ...

MICROFILTER DEVICE

A micro-filter device, suitable for removing micro-organisms such as mycoplasma from biological fluids comprises two filters in series. The first is a pre-filter. The second is a porous asymmetric inorganic membrane, in which the pores adjacent one face are larger diameter than those adjacent the other face, the large-pore face being positioned facing upstream.

METHOD OF DEWAXING A VEGETABLE OIL

APPARATUS, MEMBRANES AND METHODS FOR REMOVING ORGANIC COMPOUNDS FROM A BIOLOGICAL FLUID

A membrane (10) and a method for making a membrane (10) are disclosed. The membrane (10) includes a polymeric matrix (16) and a particulate material immobilized within the matrix (16). The membrane (10) may include a support (18) within the core of the mebrane (10) and may further include a skin (19). The membrane (10) may find particular application in methods and apparatus for removing organic compounds from a biological fluid as part of a pathogen inactivation treatment.

PROCESS GAS PURIFICATION AND FUEL CELL SYSTEM

A module (214 Fig. 5) for separating a product from a mixed stream comprises a mixed stream chamber having inlet and outlet means and defining a first flow path for the mixed stream, a purge/product stream chamber having inlet and outlet means and defining a second flow path for a purge/product stream, the second flow path having a substantially countercurrent direction to that of the first flow path, and a membrane located between the mixed stream chamber and the purge/product stream chamber, the membrane being selectively permeable to the product. There is also disclosed a fuel cell system comprising a burner module (210) for mixing and combusting a fuel and air mixture to produce hydrogen rich fuel stream; a hydrogen fuel cell (250) for producing power/energy using the hydrogen fuel produced by the burner module; a hydrogen purification module (214) between the burner module and the fuel cell for extracting hydrogen fuel from the burner module for use in the fuel cell and that uses a ...

MICROFLUIDIC CHIP FOR BIOMOLECULE CRYSTALLIZATION

A system for crystallizing a protein and other biomolecules, the general scheme of which is represented in Figure 1, comprises a flow channel (12) for conveying a solution containing the biomolecule to be crystallized and one or more substations (40, 50, 60, 70) related to the crystallization process formed along the flow channel. The system operates by flowing a biomolecule solution through the flow channel (12), then performing dialysis on a micro- scale to set crystallization conditions. After dialysis, the concentration of the biomolecule solution is changed by removing water or solvent from the biomolecule solution to promote formation of crystals in a segment of the flow channel. Formed crystals may be observed and harvested from the flow channel.

RESIN BARRIER DEVICE, GASKET AND METHOD FOR INFUSING A PREFORM

Disclosed is a resin barrier device (1) for connection in a vacuum line, for use in resin infusion during composite manufacture. The resin barrier device includes a housing (3) having an inlet port (9) for connection to a resin source; and an outlet port (11) for connection to a vacuum source, and a flow path (13) extends between the inlet and outlet ports. A gas-permeable membrane (15) is disposed across the flow path (13) to prevent resin from flowing to the vacuum pump. Also disclosed is a gasket (17) for supporting the membrane (15), adapted to prevent resin leakage and a method of infusing a preform with a resin.

METHODS AND APPARATUS TO SELECTIVELY EXTRACT CONSTITUENTS FROM BIOLOGICAL SAMPLES

Methods and apparatus provide filtration for concentrating analytes, such as bacteria or exosomes, of a biological sample, such as blood or urine. The technology may employ membrane devices that implement one or more tangential flow filtration processes such as in stages. An example membrane device may typically include a membrane having sides and ends. The membrane may selectively permit constituent(s) of the sample to pass through while retaining other constituents at one side. An input chamber of the device may include an inlet near one end and an outlet near the other end, and that may permit a tangential flow of the sample along the first side surface, and a trans-membrane passing of constituent(s). An output chamber of the device may be configured at the second side surface to receive the passing constituents. Such devices may be provided in a kit to facilitate targeting of a desired biological analyte concentration.

PREPARATION OF ASBESTOS FIBERS

APPARATUS FOR THE SEPARATION OF PLASMA

The invention relates to an apparatus for separating blood, more particularly an apparatus (1) for absorbing blood (19) and separating blood components, e.g. blood plasma, as a sample liquid (2). Said apparatus (1) comprises a feeding device (13) for absorbing the blood (2), a device (15) for separating blood components as a sample liquid (2), a duct which preferably absorbs the sample liquid (2) exclusively by means of capillary forces, and a device for filling the duct (3) with sample liquid (2) in an inlet or feeding zone (18) of the duct (3). The separating device (15), in particular a membrane, is curved, especially convexly shaped, and the apex of said curved, especially convex shape projects into the filling device.

VENT FILTER AND METHOD FOR MANUFACTURING THE SAME

A vent filter wherein a vent film is less likely to be broken when cut, and a measure to shrinkage is taken while keeping properties or functions characteristic to the vent film is maintained. The vent filter, which comprises a frame-shaped adhesion layer (2) and the vent film (3) made to adhere to the adhesion layer (2), is configured such that the periphery of the vent film (3) is outside that of the frame-shaped adhesion layer (2).

APPARATUS FOR COLLECTION AND TRANSFER OF PARTICLES AND MANUFACTURE THEREOF

... 2109299 9317090 PCTABS00025 A device for collecting particles, such as human cells, from a fluid sample, and for transferring the collected particles to a receiver, such as a glass microscope slide, provides substantially exact replication of the spatial distribution of the cells on the collection device. The device supports a surface-collecting filter on a tubular rim, with a precise degree of flatness, and fastens the filter in place at a mounting shoulder recessed below the rim. Distortions of the mounting shoulder or of the filter at the mounting shoulder, caused by securing the filter to the shoulder, are confined to the shoulder structure, and do not detract from the desired precision flatness of the filter and rim structure.

APPARATUS FOR COLLECTION AND TRANSFER OF PARTICLES AND MANUFACTURE THEREOF

A device for collecting particles, such as human cells, from a fluid sampl e, and for transferring the collected particles to a receiver, such as a glass microscope slide, provides substantially exact replication of the spatial distribution of the cells on the collection device. The device supports a surface-collecting filter on a tubular rim, with a precise degree of flatness, and fastens the filter in place at a mounting shoulder recessed below the rim. Distortions of the mounting shoulder or of the filter at the mounting shoulder, caused by securing the filter to the shoulder, are confined to the shoulder structure, and do not detract from the desired precision flatness of the fitter and rim structure.

VAPOR PERMEATION SYSTEM

A gas-phase countercurrent sweep stream having a low partial pressure of a given vapor to be selectively removed from a mixture of condensable vapors is swept past the permeate side of a selectively permeable membrane, thereby rendering unnecessary the application of a vacuum to the permeate side of the membrane and at the same time maintaining a chemical potential gradient of the vapor to be removed across the membrane.

AN IN-LINE BLOOD FILTRATION DEVICE

An in-line liquid filtration device (23) useable for filtration of blood includes a housing (1, 2) having an inlet port (15), an outlet port (16), at least one filter element (5) disposed in the housing (1, 2) between the inlet port (15) and outlet port (16) so as to filter liquid which flows into the filtration device (23) via an inlet port (15). The filter element (5) divides the housing into a first chamber (30) and a second chamber (29). Gases in the filtration device (23) are vented through the outlet port (16). The filtration device (23) includes a flow deflector (10) and/or a channel, preferably spiral, within the first chamber (30) and/or the second chamber (29).

OZONE PURIFICATION PROCESS

An ozone-oxygen gas stream is introduced into feed side of a membrane separation unit containing an elastomeric polymer membrane. Ozone-enriched gas passes through the membrane to a permeate zone and is contacted with an ozone- reactive substance-containing gas stream in the permeate zone, thereby oxidizing the substances or is removed from the permeate zone. Removal of the ozone-enrich ed gas from the permeate zone may be effected by purging the permeate zone with an inert gas and/or evacuating the permeate zone. Ozone-enriched gas removed fr om the permeate zone may be mixed with a liquid or gas stream which contains ozone- reactive substances in, for example, a venturi device, thereby oxidizing the substances.

Installation de dialyse, utilisable notamment pour la dialyse des liquides organiques.

Verfahren und Vorrichtung zur Gewinnung von Feststoffen in angereicherter Form

Ultrafilter mit einer semipermeablen Filtermembran aus Cellulosederivat

Verfahren zur Behandlung von für die Filtration von Virusflüssigkeiten bestimmten Entkeimungsfiltern

Verfahren zur Anreicherung eines wasserstoffhaltigen Gasstroms mit Wasserstoff oder zur Gewinnung eines Stromes von reinem Wasserstoff aus einem wasserstoffhaltigen Gasstrom und Vorrichtung zur Durchführung des Verfahrens

Dialysator

Device for ultrafiltration.

Disposable filter

Disposable filter

In known disposable filters for filtration, in particular pressure filtration, in which a housing top and a housing bottom are each furnished with a flange, the filter element is inserted between the flanges by which the filter housing is sealed. As a result, the compressive strength of the disposable filter is impaired. In addition, engineering problems with regard to the positioning of the filter element occur in the production of the disposable filter. In order to achieve high compressive strength and simplified assembly, in the novel disposable filter, the housing top (1) and the housing bottom (2) each have an external flange (7 and 8 respectively), which both lie flat directly against each other, while the filter element (3) lies in a cup-like recess of the housing bottom (2) and is tightened by its outer edge by means of a downwardly drawn edge (10) of the housing top (1) penetrating telescopically into the housing bottom. The disposable filter is sealed by a closure ring (9) injection ...

FILTER DIAPHRAGM WITH SEALING AND PROCEDURE FOR YOUR PRODUCTION.

TEST CELL FOR DIAPHRAGM PROCEDURES.

ФИЛЬТРОВАЛЬНАЯ ПЛАСТИНА

Изобретение относится к микропористой фильтровальной пластине, используемой в вакуумной сушилке, в частности в капиллярном фильтре, содержащей мембрану со средним размером пор около 1 мкм, подложку, на которой расположена мембрана, и область с полостями внутри фильтровальной пластины для фильтрата и для жидкости для обратной промывки. Согласно изобретению область с полостями внутри фильтровальной пластины снабжена опорными элементами, у которых отношение между самым длинным размером и самым коротким размером составляет максимум 1,5 в поперечном сечении, параллельном фильтрующей поверхности фильтровальной пластины, для обеспечения возможности прохождения жидкости, по существу, одновременно и легко во всех направлениях и для обеспечения конструкции фильтровальной пластины способности выдерживать напряжения, основанные на пиках давления.

MBR (Menbrane Bioreactor) flat-sheet membrane element, MBR flat-sheet membrane component and application thereof

Water purification device

With water-absorbing filter assembly of the filter plate of products

IMPROVEMENTS IN FILTER UNIT

Process and apparatus for the concentration of hydrogen

Natural stone diaphragm for dialysers

FILTRE POUR DES SYSTEMES DE CANALISATIONS VEHICULANT DU SANG

FILTRE POUR DES SYSTEMES DE CANALISATIONS VEHICULANT DU SANG. LE BOITIER DU FILTRE COMPREND DEUX PARTIES 11, 12 DONT CHACUNE COMPORTE UNE FACE DE SERRAGE 19A, 19B. LE BORD DE LA MEMBRANE 15 EST MAINTENU PAR SERRAGE ENTRE LES FACES 19A, 19B. LES PARTIES DU BOITIER SONT REUNIES ENSEMBLE PAR UNE SOUDURE 26 QUI EST SEPAREE DE LA MEMBRANE PAR UNE FENTE ETROITE 29. DES PARTICULES DE SOUDURE, QUI PEUVENT SE FORMER PENDANT LE SOUDAGE AUX ULTRASONS, SONT AINSI EMPECHEES D'EMIGRER DE LA SOUDURE 26 VERS LA PARTIE ACTIVE DE LA MEMBRANE 15 DU FILTRE.

TOTALLY ENCLOSED LIQUID PERMSELECTIVE MEMBRANE

PROCESSES AND EQUIPMENT FOR PRODUCING IN THE BEST CONDITIONS OF EFFICIENCY AND HYGIENE STEP DESALTING FOOD PRESERVED BY SALTING.

La présente invention concerne un procédé et un équipement de dessalage d'un produit alimentaire consistant à placer ledit produit alimentaire dans un premier volume (1) contenant un premier bain, et séparé d'un second volume par une membrane osmotique (4).

FILTRATION ASSEMBLY FOR FILTERING NANOPARTICLES COMPRISING A FILTER AND A FILTER SUPPORT, APPARATUS AND METHOD OF MOUNTING THE ASSEMBLY ASSOCIES AND METHOD FOR COLLECTING AND ANALYZING THE SAME NANOPARTICLE.

La présente invention concerne un ensemble de filtration pour filtrer des nanoparticules, comportant : - un filtre (3) à pores aptes à retenir en leur sein des nanoparticules susceptibles d'être présentes dans un flux d'air destiné à passer à travers le filtre, - un support de filtre comportant deux parties dont : • une partie inférieure formant socle (2) comportant une portée périphérique sur laquelle le filtre est apte à être en appui ; • une partie supérieure en forme de bague (1) apte à être montée autour de la portée du socle, le jeu de montage entre la bague et la portée du socle étant dimensionné de sorte à maintenir sous tension mécanique par pincement le filtre, en appui sur la portée, selon une direction radiale à la direction de montage.

FILTER HOLDER

Process for improving the flow in the ultrafiltration of the amino acids obtained by microbial fermentation.

APPAREIL ET PROCEDE DE FRACTIONNEMENT DU SANG

L'appareil comprend : un logement 100 comportant une entrée de sang 110 destinée à être raccordée à une source de sang, une sortie de sang 120 en communication de fluide avec l'entrée de sang, et une sortie de fraction de sang; une membrane semi-perméable 180 qui sépare la sortie de fraction de sang de l'entrée et de la sortie de sang et qui permet à la fraction de sang de la traverser; et une plaque perforée 150 qui envoie des jets de sang très rapides vers et le long d'une surface 181 de la membrane de façon à empêcher la membrane de se colmater au point que la fraction de sang ne puisse plus la traverser. Recueil du plasma, du sérum, des immuno-globulines, etc.

Microbiological examination device for sample of liquid under pressure, has second seal with arched profile, external annular end and internal annular end connected to elastomer seal

Il s'agit d'un dispositif dont la membrane filtrante est pincée annulairement en périphérie entre une paroi transversale annulaire (32) faisant partie d'un corps de drainage et une paroi cylndridue (9) orientée axialement d'un corps d'admission, laquelle paroi latérale comporte un joint en élastomère (13) qui en forme la tranche et par lequel cette paroi rentre en contact avec la membrane (4), ce dispositif étant muni d'un deuxième joint (55) qui présente un profil en arche, dont l'extrémité annulaire externe (61) porte contre ladite paroi transversale annulaire (32) radialement au-delà de ladite membrane (4), et dont l'extrémité annulaire interne (57) est raccordée audit joint (13) que comporte la paroi latérale (9) de ladite cuvette (5), ci-après appelé premier joint.

SELF-CLEANING ULTRAFILTER

APPARATUS AND DEVICE OF DIFFUSION HAVE MEMBRANE FOR THE TREATMENT OF BLOOD AND MANUFACTORING PROCESS

Improvements with the apparatuses of ultrafiltration

NOVEL APPARATUS FOR THE TREATMENT AND STORAGE OF WATER

capsule for the preparation of a nutritional product and filter device

DRINKING WATER SERVER

Provided is a drinking water server whereby, using a simple structure, bacterial invasion with the introduction of outside air can be prevented and bacterial proliferation within the drinking water server can be inhibited. The drinking water server is provided with an air filter (1) for introducing outside air, which comprises a porous film being formed of a fluororesin and having a pore diameter of 0.2-0.8 μm, and protective porous films fixed to both faces of the aforesaid porous film. In the drinking water server, moreover, an antibacterial member (2), which comprises multiple antibacterial particles comprising a low-density polyethylene and an ion exchanger, wherein silver ions are ionically bound to zeolite, said multiple antibacterial particles being sealed in a water-permeable porous bag, is placed in a tank.

METHODS, SYSTEMS AND DEVICES FOR SEPARATING TUMOR CELLS

Embodiments of the present disclosure are directed to the separation/capture of specific cells and/or contaminants, as well as the determination, monitoring, and treatment of cancer. Moreover, some embodiments are directed to methods, systems and devices for removing cancer, stem and/or tumor cells in vivo or in vitro from a bodily fluid to prevent or impede the proliferation of a cancer. Some embodiments provide a blood-compatible filter comprising, for example, a membrane provided with a number of openings (preferably precise) which yield minimal detrimental effect both quantitatively and qualitatively on cells present in the bodily fluid during the separation process. For example, in some embodiments, a majority percentage of circulating tumor cells are captured by a filter while a majority percentage of leukocytes, for example, are allowed to pass, where the passed leukocytes retain their vitality.

APPARATUS, MEMBRANES AND METHODS FOR REMOVING ORGANIC COMPOUNDS FROM A BIOLOGICAL FLUID

L'invention porte sur une membrane (10) et sur un procédé de fabrication de cette membrane (10). La membrane (10) comprend une matrice polymère (16) et une matière particulaire immobilisée dans la matrice. L'âme de la membrane (10) peut également comporter un support (18) et la membrane (10) peut également présenter une couche (19) superficielle. Cette membrane peut être notamment utilisée avec un appareil et dans des procédés permettant d'éliminer des composés organiques d'un fluide biologique, dans le cadre d'un traitement d'inactivation d'agents pathogènes.

PROCESS AND DEVICE FOR CONCENTRATING MACROMOLECULAR SOLUTIONS

The invention concerns a process for concentrating macromolecular solutions, in particular of protein molecules, to a given end volume in the mul-range and a filter for carrying out the process. The liquid phase of any desired volume of solution is forced through a vertical filter paper. The filtered components are directed downwards under gravity and collected in concentrate cavity (4).

PERMEATION METHOD AND APPARATUS FOR PREPARING FLUIDS CONTAINING HIGH PURITY CHLORINE DIOXIDE

Method to prepare fluids (liquids and gases) containing pure chlorine dioxide which is not contaminated by the starting materials or the byproducts of the chlorine dioxide synthesis or to deliver pure chlorine dioxide into any medium capable of dissolving chlorine dioxide, wherein the chlorine dioxide generated in the process is transported across a pore free polymeric membrane via selective permeation into the target medium. Apparatus to realize the said method, wherein the generation of chlorine dioxide is carried out in such a reactor where some or all walls comprising the reactor, or the walls of a permeator unit attached to the reactor, are made of the said pore free polymer, characteristically some kind of silicone rubber, which is highly permeable to chlorine dioxide, but which is practically impermeable for the acidic and corrosive reagents used for the chlorine dioxide synthesis, its permeability being at least 3 orders of magnitude lower for these contaminating components compared ...

Membrane laminate

A laminate is provided comprising at least one polysulfone and/or polyethersulfone porous membrane heat bonded to a polyvinylidene fluoride substrate.

Reverse osmosis element

A reverse osmosis water purification module has an enclosed cylindrical housing in which at least twelve purification elements are mounted in a uniform, spaced parallel fashion. Each element consists of a long flat member having a thermoplastic sheet backing formed into a slightly curved cross section and having a semi-permeable membrane disposed thereon. The backing has three-dimensional porosity for purified water such that water passing through the membrane portion of the element travels along the backing member to an end. The ends of the module are mounted in a collection manifold which is sealed off from the remainder of the housing interior. A method of manufacturing the elements continuously is also provided wherein a continuous length of flexible backing material is fed sequentially through a heater, a forming die to impart a curved cross-section to the backing material, an extruder wherein membrane forming fluid is extruded around the periphery of the backing, a chill bath and ...

Multiple compartment filter and method for processing parenteral fluid

Methods and devices are disclosed for passing a first parenteral fluid through a first fluid flow path through a fluid treatment arrangement, passing a second parenteral fluid through a separate and isolated second fluid flow path through the fluid treatment arrangement, and passing the first parenteral fluid through the separate and isolated second fluid flow path through the fluid treatment arrangement.

Extracorporeal pathogen reduction system

The invention relates to an apparatus system and methods for treatment of virus-infected or pathogen-loaded human blood components separated from normal components comprising a separation apparatus and treatment apparatus system that inactivate pathogens in an extracorporeal blood system.

SYSTEMS, METHODS AND DEVICES RELATING TO A CELLULARIZED NEPHRON UNIT

The present invention relates to bioartificial devices and systems that mimic kidney or nephron function and methods of making them.

INSTRUMENTS, MODULES, AND METHODS FOR IMPROVED DETECTION OF EDITED SEQUENCES IN LIVE CELLS

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.

Method for Extracting Gas from Liquid

A method for extraction of gas from liquid provides for reliable and accurate extraction of gases dissolved in fluids and routing the extracted gas to an analytical instrument. An extraction module comprises one or more fluorosilicone membranes molded into the shape of a flattened disk. The membranes are retained in a housing in a spaced apart relationship. The membrane is permeable to target gas(es), but not to the fluid. Porous support members support the membranes and prevent damage to them and the housing defines separate fluid flow paths for the fluid and the gas extracted from it. Fluid is passed over the membrane in a first fluid phase; target compounds in the fluid diffuse across the membrane to a second fluid phase until equilibrium is achieved.

Vent filter and electric device using the same

It is an object to provide a vent filer that can reduce contaminants diffusing through the vent filter into the inside of a housing, and has high diffusion efficiency and low pressure loss. The vent filter has an adhesive layer 1 having a through-hole 1 a at least in one area; a flow path member 2 provided with a flow path 2 a in communication with the through-hole 1 a; and an air-permeable membrane 3 covering the flow path member 2 and part of the adhesive layer 1, wherein the peripheral portion 3 a of the air-permeable membrane 3 is fixed to the adhesive layer 1 and the flow path member 2 is held within a hollow portion formed between the adhesive layer 1 and the air-permeable membrane 3.

Devices for separating cells and methods of using them

The present invention refers to a device for separating cells of a defined size from a sample and to a system comprising such devices and further components. Such devices can comprise different components, such as inlet module, intermediate module, outlet module and microsieve. The present invention also refers to methods of operating such devices and uses thereof.

Method and system for cell filtration

Methods and systems disclosed in the present application include membrane-like filters and methods and systems that employ these membrane-like filters to isolate circulating tumor cells and other abnormal cells from biological fluids, such as blood. The disclosed methods and systems use membrane-like filters that include a pattern or array of small, tapered apertures fabricated within a relatively thin but mechanically robust polymeric material that resists accumulation of biological-solution components and clogging during filtration of biological solutions.

Membrane separation apparatus, membrane separation apparatus operation method, and evaluation method using the membrane separation apparatus

A submodule is used to know exactly fouling of a membrane surface in a separation membrane module. The membrane separation apparatus of the present invention includes: a separation membrane module ( 1 ) configured to produce at least a permeate fluid from a feed fluid; and at least one submodule ( 2 ) having a separation membrane ( 23 ) made of the same material as a separation membrane in the separation membrane module ( 1 ). A deposition member ( 22 ) is provided on a surface of the separation membrane ( 23 ) in the submodule ( 2 ), and the feed fluid is supplied onto the surface.

Syringe Filter

A syringe filter for containing a filter membrane is disclosed and includes first and second fluid distribution surfaces configured to be positioned on opposing sides of a membrane. An inlet port is in fluid communication with the first fluid distribution surface and a first plurality of distribution pathways formed on the first fluid distribution surface. An outlet port is in fluid communication with the second fluid distribution surface and a second plurality of distribution pathways formed on the second fluid distribution surface. The first plurality of distribution pathways is configured to distribute fluid flow from the inlet port to one side of the membrane while the second plurality of distribution pathways is configured to direct fluid flow from another side of the membrane to the outlet port.

Hydrogen generation assemblies and hydrogen purification devices

Hydrogen generation assemblies, hydrogen purification devices, and their components are disclosed. In some embodiments, the devices may include a permeate frame with a membrane support structure having first and second membrane support plates that are free from perforations and that include a plurality of microgrooves configured to provide flow channels for at least part of the permeate stream. In some embodiments, the assemblies may include a return conduit fluidly connecting a buffer tank and a reformate conduit, a return valve assembly configured to manage flow in the return conduit, and a control assembly configured to operate a fuel processing assembly between run and standby modes based, at least in part, on detected pressure in the buffer tank and configured to direct the return valve assembly to allow product hydrogen stream to flow from the buffer tank to the reformate conduit when the fuel processing assembly is in the standby mode.

Filtration device with multiple post-filtration orientations

A cell filtration assembly adapted to capture cells from a biological sample during centrifugation includes a centrifugation tube, a cell collection device adapted to be secured within a tapered end of the centrifugation tube and a funnel structure adapted to direct fluid into the cell collection device. The cell collection device includes a rectilinear structure that is adapted to permit fluid to flow through the rectilinear structure and a cell capture surface that is secured relative to the rectilinear structure. The cell collection device may be sectioned in either a horizontal or vertical orientation.

Modular filtration system

A filtration vessel, having within constituent filter media is formed using plastic injection molding to meet the interior specifications of a high-pressure filtration encasement system while remaining a separate replaceable component. The encasement system supports and encases walls of the filtration vessel enabling the vessel to be designed with sufficient strength and resiliency to form a seal and constrain filter media prior to and after use without necessitating construction to endure independent high-pressure operations. The bottom or base of the vessel includes a plurality of holes through which the filtrate may flow. Interposed between the base of the vessel and the filter media is a semi-permeable barrier imbedded into the injection molded walls and base of the vessel. The barrier prevents residue from contaminating the filtrate.

Semipermeable Membrane and Process Using Same

An enhanced process for semipermeable membrane performance. Counter flowing chambers on either side of a semipermeable membrane is disclosed. Each comprise turbulent flow injectors and flow deflector cells giving rise to swirling and turbulent boundary layer conditions. The disclosed invention obviates concentration polarization in osmotic systems and maximizes flux (fluid flow) through the semipermeable membrane. This invention fills a need in large volume, forward osmosis water purification systems.

Plasma Separation Device

Devices and methods are provided that permit efficient and selective separation of liquid biological specimens into at least two constituent components to facilitate subsequent quantitative and qualitative analysis on at least one analyte of interest in at least one of the components. The devices generally include one or more sample deposition regions supported on a base. Each sample deposition region includes a separation membrane for separating the liquid biological specimen into two different fractions. The first fraction is trapped by the separation membrane while the second fraction passes through the separation membrane and into a respective collection membrane. The separation and collection membranes are easily separable from the devices and can be utilized for further processing and analysis.

FILTRATION HEAD FOR A FILTER SYSTEM AND FUNNEL FOR USE IN CONJUNCTION WITH A FILTRATION HEAD

Filtration head () for a filter system, comprising base () including filter support () for removable filter element () and a fluid path from one side of filter element () on filter support (), through filter element (), and to drainage outlet () of base (), and holder device () for removably attaching funnel () to base () to form a sample fluid reservoir on one side of filter element (), wherein holder device () comprises ring-shaped element () configured to extend about bottom peripheral flange () surrounding a lower end of funnel () and to selectively apply a biasing force on a radially outward protruding portion () of bottom peripheral flange () of funnel () to press funnel () against base (). The filtration head allows the use of cardboard funnels without risk of liquid leakage between the funnel and the base. 11. A filtration head () for a filter system , comprising{'b': 2', '3', '4', '4', '3', '4', '5', '2, 'a base () including a filter support () for a removable filter element () and a fluid path from one side of the filter element () to be placed on the filter support (), through the filter element (), and to a drainage outlet () of the base (), and'}{'b': 6', '7', '2', '4, 'a holder device () for removably attaching a funnel () to the base () to form a sample fluid reservoir on the one side of the filter element (),'}{'b': 6', '8', '7', '7', '7', '7', '7', '7', '2, 'i': a', 'b', 'a, 'wherein the holder device () comprises a ring-shaped element () configured to extend about a bottom peripheral flange () surrounding a lower end of the funnel () and to selectively apply a biasing force on a radially outward protruding portion () of the bottom peripheral flange () of the funnel () to press the funnel () against the base ().'}212237722aaa. The filtration head () for a filter system according to claim 1 , wherein the base () has a contact face () surrounding the outer periphery of the membrane support () for a fluid tight contact with the bottom peripheral flange ...

Fabrication of hierarchical silica nanomembranes and uses thereof for solid phase extraction of nucleic acids

The present invention provides a novel method to fabricate silica nanostructures on thin polymer films based on silica deposition and self-wrinkling induced by thermal shrinkage. These micro- and nano-scale structures have vastly enlarged the specific area of silica, thus the silica nanomembranes can be used for solid phase extraction of nucleic acids. The inventive silica nanomembranes are suitable for nucleic acid purification and isolation and demonstrated better performance than commercial particles in terms of DNA recovery yield and integrity. In addition, the silica nanomembranes have extremely high nucleic acid capacity due to its significantly enlarged specific surface area of silica. Methods of use and devices comprising the silica nanomembranes are also provided.

BLOOD FILTER AND METHOD FOR FILTERING BLOOD

The present invention relates to a method for filtering blood to produce plasma or serum and to a blood filter for the production of plasma or serum from a blood sample. The invention further relates to a kit comprising a blood filter for the production of plasma or serum from a blood sample and a syringe. 1. A blood filter for the production of plasma or serum from a blood sample , comprising:a filter membrane having opposite first and second sides;a receiving compartment defining a hollow space for receiving a blood sample to be filtered, said receiving compartment being arranged on said first side of the filter membrane, the filter membrane resting on a seating, wherein at least 50% of the surface of the second side of the filter membrane is in contact with said seating, and wherein the seating comprises a plurality of channels for collecting the filtered blood sample.2. The blood filter of claim 1 , wherein the seating is convex having a radius of curvature between 30 and 150 mm.3. The blood filter of claim 2 , wherein at least 75% of the surface of the second side of the filter membrane is in contact with said seating.4. The blood filter of claim 3 , wherein the plurality of channels cover between 0.5% and 15% of the surface of the seating.5. The blood filter of claim 4 , wherein the plurality of channels forms a sampling compartment having a volume in the range between 0.06 mmand 3.5 mmper cmof the filter surface.6. The blood filter of claim 1 , wherein the blood filter comprises a single filter membrane. This application is a divisional of U.S. patent application Ser. No. 14/964,049, filed Dec. 9, 2015, which is a divisional of U.S. patent application Ser. No. 13/378,991, having a filing date of Jan. 30, 2012, which is a U.S. National Stage Application filed under 35 U.S.C. § 371 based upon International Application No. PCT/EP2010/058551, filed Jun. 17, 2010, which application claims priority to European Application No. 09163006.1, filed Jun. 17, 2009, the ...

HYDROGEN GENERATION ASSEMBLIES AND HYDROGEN PURIFICATION DEVICES

Hydrogen generation assemblies, hydrogen purification devices, and their components are disclosed. In some embodiments, the devices may include a permeate frame with a membrane support structure having first and second membrane support plates that are free from perforations and that include a plurality of microgrooves configured to provide flow channels for at least part of the permeate stream. In some embodiments, the assemblies may include a return conduit fluidly connecting a buffer tank and a reformate conduit, a return valve assembly configured to manage flow in the return conduit, and a control assembly configured to operate a fuel processing assembly between run and standby modes based, at least in part, on detected pressure in the buffer tank and configured to direct the return valve assembly to allow product hydrogen stream to flow from the buffer tank to the reformate conduit when the fuel processing assembly is in the standby mode. 1. A hydrogen purification device , comprising: an input port configured to receive a mixed gas stream containing hydrogen gas and other gases;', 'an output port configured to receive a permeate stream containing at least one of a greater concentration of hydrogen gas and a lower concentration of the other gases than the mixed gas stream; and', 'a byproduct port configured to receive a byproduct stream containing at least a substantial portion of the other gases;, 'first and second end frames includingat least one hydrogen-selective membrane disposed between and secured to the first and second end frames, the at least one hydrogen-selective membrane having a feed side and a permeate side, at least part of the permeate stream being formed from the portion of the mixed gas stream that passes from the feed side to the permeate side, with the remaining portion of the mixed gas stream, which remains on the feed side, forming at least part of the byproduct stream; and a perimeter shell,', 'an output conduit formed on the perimeter ...

INJECTING A LIQUID BORNE SAMPLE INTO A FIELD FLOW FRACTIONATOR

The present invention an apparatus and method of injecting a liquid borne sample into a field flow fractionator and a method of forming a top plate and spacer. In an embodiment, the field flow fractionation unit includes a top plate including a sample injection inlet port, a sample injection outlet port, and a spacer including a separation channel cavity defining at least a portion of the separation channel, a sample injection inlet cavity configured to be in fluid contact with the separation channel and located substantially beneath the sample injection inlet port, a sample injection outlet cavity configured to be in fluid contact with the separation channel and located substantially beneath the sample injection outlet port, such that the injection inlet and outlet paths are configured to define an injection channel that is essentially perpendicular to the length of the separation channel spanning the width of the separation channel cavity. 1. A field flow fractionation unit comprising: a sample injection inlet port configured to allow a liquid borne sample to be injected into a separation channel,', 'a sample injection outlet port configured to allow liquid contained within the separation channel to be withdrawn; and, 'a top plate comprising'} [ 'wherein the separation channel is defined by a surface of the top plate, sidewalls of the spacer, and a surface of a membrane,', 'a separation channel cavity defining at least a portion of the separation channel,'}, 'wherein the sample injection inlet cavity is configured to act as an injection inlet path,', 'a sample injection inlet cavity configured to be in fluid contact with the separation channel and located substantially beneath the sample injection inlet port,'}, 'wherein the sample injection outlet cavity is configured to act as an injection outlet path,', 'a sample injection outlet cavity configured to be in fluid contact with the separation channel and located substantially beneath the sample injection outlet ...

FILTRATION ASSEMBLY AND METHOD FOR MICROBIOLOGICAL TESTING

The invention concerns a filtration assembly () for microbiological testing and a method of using the filtration assembly for that purpose. The filtration assembly () comprises a ring-like membrane support () holding a filtration membrane (), a cylindrical reservoir () of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support () to define a sample volume adjacent to the filtration membrane () on one axial side of the membrane support (); and a drain member () removably and fluid tightly attachable to the membrane support () to define a drain channel space adjacent to the filtration membrane () on an opposite axial side of the membrane support (). 11. A filtration assembly () for microbiological testing , comprising:{'b': 10', '11, 'a ring-like membrane support () holding a filtration membrane ();'}{'b': 20', '10', '11', '10, 'a cylindrical reservoir () of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support () to define a sample volume adjacent to the filtration membrane () on one axial side of the membrane support (); and'}{'b': 30', '10', '11', '10, 'a drain member () removably and fluid tightly attachable to the membrane support () to define a drain channel space adjacent to the filtration membrane () on an opposite axial side of the membrane support ().'}21. The filtration assembly () according to claim 1 , further comprising:{'b': 40', '20', '40', '10', '10, 'a lid device () removably and fluid tightly attachable to the other axial opening of the reservoir () to close the opening, wherein the lid device () is removably and fluid tightly attachable to the membrane support () so as to seal the one axial side of the membrane support () from the environment,'}{'b': 40', '41', '40', '40, 'i': 'a', 'wherein the lid device () has a hinge () for supporting a lid portion () so as to allow selective opening of the lid device ...

AIR SEPARATION DEVICE AND REFRIGERATING AND FREEZING DEVICE

An air separation device and a refrigerating and freezing device. The air separation device comprises a support frame and an air separation membrane, wherein a supporting surface with a channel and an enriched-gas collection chamber communicated with the channel are formed in the support frame. The air separation membrane laid on the support surface of the support frame and configured to enable more of a specific gas than other gases in airflow of the space around the air separation device to enter the enriched-gas collection chamber through the air separation membrane. According to the air separation device provided by the present invention, the support frame is specially designed to adopt the structure provided with the support surface and the enriched-gas collection chamber, the channel communicated with the enriched-gas collection chamber is formed on the support surface, and the air separation membrane is disposed on the support surface. 1. An air separation device , comprising:a support frame on which a support surface with a channel and an enriched-gas collection chamber communicated with the channel are formed; andan air separation membrane laid on the support surface of the support frame and configured to enable more of a specific gas than other gases in airflow of the space around the air separation device to enter the enriched-gas collection chamber through the air separation membrane.2. The air separation device according to claim 1 , wherein:the support frame comprises an air extraction hole communicated with the enriched-gas collection chamber to allow the specific gas in the enriched-gas collection chamber to be output.3. The air separation device according to claim 2 , wherein the support frame further comprises:a side frame in which a receiving chamber with an opening is defined; anda plurality of ribbed plates disposed at intervals at the opening of the receiving chamber; whereinouter side surfaces of the plurality of ribbed plates form the support ...

Systems, Methods, and Devices for Sample Collection, Stabilization and Preservation

Herein, systems and methods are disclosed including a sample acquisition component (SAC) for user-friendly sample collection, a separation component for optional separation of plasma, and one or more stabilization components for stabilizing analytes. In a particular embodiment, the system and methods are directed towards sample collection and stabilization with optional sample separation. Other embodiments can perform any combination of collection, separation, stabilization or detection.

Filtration Cell and Method for Filtering a Biological Sample

A filtration cell () for a biological sample including an upper chamber for receiving the biological sample to be filtered, a lower chamber in fluid communication with the upper chamber, and a filtration membrane () positioned between the upper chamber and the lower chamber is disclosed. A surface of the filtration membrane has a contact angle >90°. The flow of the biological sample through the upper chamber may be tangential to the filtration membrane and a filtrate passing through the filtration membrane may be collected in the lower chamber. Also, a method of filtering a biological sample including passing the biological sample through an upper chamber of a filtration cell as described above and collecting a filtrate in the lower chamber is disclosed. 1. A filtration cell for a biological sample comprising:an upper chamber for receiving the biological sample to be filtered;a lower chamber in fluid communication with the upper chamber; anda filtration membrane positioned between the upper chamber and the lower chamber,wherein a surface of the filtration membrane has a contact angle ≧90°.2. The filtration cell of claim 1 , wherein a whole blood sample is provided in the upper chamber and a separated plasma portion is collected in the lower chamber.3. The filtration cell of claim 1 , wherein the filtration membrane comprising a plurality of pores and the capillary force in each of the pores is ≦0 psi.4. The filtration cell of claim 1 , wherein the contact angle is ≦150°.5. The filtration cell of claim 1 , wherein the contact angle is 90-105°.6. The filtration cell of claim 1 , further comprising a reciprocating unit in communication with the upper chamber claim 1 , wherein the reciprocating unit reciprocates the biological sample over the filtration membrane.7. The filtration cell of claim 1 , further comprising a pressure unit in communication with the upper chamber claim 1 , wherein the pressure unit applies positive pressure to the biological sample within the ...

INSTRUMENTS, MODULES, AND METHODS FOR IMPROVED DETECTION OF EDITED SEQUENCES IN LIVE CELLS

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited. 1. A singulation assembly for a solid wall isolation , incubation and normalization (SWIIN) module comprising: an upper surface and a lower surface and a first and second end,', 'an upper portion of a serpentine channel defined by raised areas on the lower surface of the retentate member, wherein the upper portion of the serpentine channel traverses the lower surface of the retentate member for about 50% to about 90% of the length and width of the lower surface of the retentate member; and', 'at least one retentate port fluidically connected to the serpentine channel; and, 'a retentate member comprising;'} an upper surface and a lower surface and a first and second end,', 'a lower portion of the serpentine channel defined by raised areas on the upper surface of the permeate member, wherein the lower portion of the serpentine channel traverses the upper surface of the permeate member for about 50% to about 90% of the length and width of the upper surface of the permeate member, and wherein the lower portion of the serpentine channel is configured to mate with the upper portion of the serpentine channel to form the serpentine channel;', 'at least one permeate port fluidically connected to the serpentine channel;, 'a permeate member disposed under the retentate member comprisinga perforated member comprising at least 25,000 perforations disposed under and adjacent to the retentate member;a filter disposed under and adjacent to the perforated member and above and adjacent to the permeate member; anda gasket surrounding the filter.2. A SWIIN module comprising the singulation assembly of further ...

Capillary Pressure Re-Set Mechanism and Applications

Many hand-held diagnostics are limited in their functionality due to the challenging physics associated with small dimensional systems. An example of this is capillary forces in hydrophilic systems, such as the tight retention of liquid passing through a small pore filtration membrane, or capillary force driven microfluidics where, to keep liquid flowing the dimensions of the system become so small that the flow rates are too low to be useful, or the manufacturing of such devices becomes uneconomical. This disclosure details methods to ‘reset’ the capillary force condition to avoid the requirement of transient pressure spikes associated with the breakthrough pressure of small pore membranes, and avoid the necessity of extremely small microfluidic channels, which can be useful in applications such as filtration of whole blood to plasma using only suction pressure or passive capillary pressure. 1. A method of drawing liquid past a capillary barrier by placing a soluble matrix in physical contact with an exterior surface of said capillary barrier; wherein said soluble matrix , by capillary , hygroscopic , or osmotic force , draws liquid past said capillary barrier and into itself , after which a portion of said soluble matrix dissolves in said liquid; wherein said dissolution releases said liquid from said soluble matrix.2. The method of whereas said capillary barrier is a component of a membrane's or filter's breakthrough pressure.3. The method of claim 1 , whereas said capillary barrier is present at the junction of two or more microfluidic channels.4. The method of claim 1 , whereas said soluble matrix is comprised at least in part of a micro or nano-particulate or fibrous material of simple or complex salts claim 1 , sugars claim 1 , proteins claim 1 , carbohydrates claim 1 , acids or bases.5. The method of claim 1 , whereas said method is used to eliminate the breakthrough pressure of membranes or filters.6. The method of claim 5 , whereas said membrane or filter ...

FILTRATION HEAD FOR VACUUM FILTRATION, MANIFOLD FOR VACUUM FILTRATION AND METHOD OF MODIFYING AN EXISTING FILTRATION HEAD FOR VACUUM FILTRATION

A vacuum filtration head () having a receptacle for a support () for a membrane filter () for microbiological testing of a liquid substance to be drawn from an upstream side of the membrane filter () to a downstream side of the membrane filter () through the membrane filter (), or the support () for such membrane filter (), a drain chamber () located downstream of the support () and communicating with a downstream side of the membrane filter () receiving the liquid substance passed through the membrane filter (), and a drain channel () communicating with the drain chamber () at an opening () and communicating with a vacuum. A protective shield () is arranged in the filtration head () interfering with a fictive direct line connection while retaining a fluid path () to the drain channel () past the protective shield ().

FIELD FLOW FRACTIONATOR

The present disclosure describes a field flow fractionator including () a top plate assembly including (a) a first non-corrosive material, and (b) at least three fluid fittings machined (simpler) into the material, () a spacer, () a membrane, () a bottom plate assembly including (a) a second non-corrosive material, (b) a cavity machined into the second non-corrosive material, (c) a frit configured to be placed into the cavity, and (d) at least one bottom plate o-ring configured to seal the bottom plate assembly to the spacer, and () where the top plate assembly, the spacer, the membrane, and the bottom assembly define a separation channel. In an embodiment, the at least three fluid fittings including a fitting for an in-flow, a fitting for an out-flow, and a fitting for a cross-flow.

SAMPLE PREPARATION DEVICE AND METHODS OF USE

A device for isolating DNA from a sample containing cells, including a cartridge having an entrance port and an exit port, a membrane disposed between the entrance port and the exit port, and a plurality of channels between the membrane and the exit port. Additionally, systems and methods for isolating DNA from a sample containing cells and also systems and methods for amplifying and isolating single-stranded DNA from a sample containing DNA. 1. A device for isolating DNA from a sample containing cells , comprisinga cartridge having an entrance port and an exit port;a membrane disposed between the entrance port and the exit port; anda plurality of channels between the membrane and the exit port.2. The device of claim 1 , wherein the channels are adjacent to the membrane.3. The device of claim 1 , wherein each of the channels has a channel entrance claim 1 , a channel exit claim 1 , and a channel wall claim 1 , wherein the channel entrance is adjacent to the membrane.4. The device of claim 3 , wherein the channel entrance has a length and width claim 3 , wherein the length is about 0.1 mm to about 100 mm and the width is about 0.1 mm to about 10 mm.5. The device of claim 1 , having from about 2 to about 1000 channels.6. The device of claim 1 , wherein the channels are arranged in a matrix.7. The device of claim 6 , wherein the channels are adjacent to each other.8. The device of claim 6 , wherein the channels are spaced apart from each other.9. The device of claim 8 , further comprising a solid barrier between each channel entrance.10. The device of claim 1 , wherein the membrane is configured to be permeable to DNA but substantially impermeable to cells.11. The device of claim 1 , wherein the membrane is configured to be permeable to DNA but substantially impermeable to non-DNA cellular material.12. The device of claim 1 , wherein the membrane comprises a cellulose material.13. The device of claim 1 , wherein the membrane has pores.14. The device of claim 13 , ...

SYSTEMS AND METHODS FOR GASTRIC DIALYSIS

Devices, systems, and methods herein relate to performing dialysis to manage a chronic condition such as end-stage renal disease. These systems and methods may allow a patient to orally ingest a potable dialysate and excrete the dialysate via the urinary tract. In some variations, a method may include delivering a dialysate via the esophagus of a patient and draining the dialysate into a bladder of the patient. Delivering the dialysate may further comprise delivering the dialysate through the nasopharynx or oropharynx. Delivering the dialysate through the oropharynx may comprise the patient drinking the dialysate. 1. A method of performing dialysis , comprising:delivering a dialysate via the esophagus of a patient; anddraining the dialysate into a bladder of the patient.2. The method of claim 1 , wherein delivering the dialysate further comprises delivering the dialysate through the nasopharynx or oropharynx.3. The method of claim 2 , wherein delivering the dialysate through the oropharynx comprises the patient drinking the dialysate.4. The method of claim 1 , further comprising transitioning a first valve disposed in a gastroesophageal junction of the patient between a first configuration and a second configuration claim 1 , the first configuration configured to form a first path between the esophagus and a stomach compartment claim 1 , and the second configuration configured to form a second path between the esophagus and a dialysate compartment claim 1 , wherein the dialysate is delivered into the dialysate compartment.5. The method of claim 4 , further comprising transitioning a second valve between a closed position and an open position claim 4 , the second valve coupling the dialysate compartment and urinary tract claim 4 , and the second valve configured to drain the dialysate into the bladder.6. The method of claim 4 , further comprising transitioning the first valve between the second configuration and a third configuration claim 4 , the third configuration ...

Membrane Gas/Liquid Contactor

A membrane gas-liquid contactor is arranged to define a fluid flow path for contact with a membrane in a manner to improve degassing efficiency. A degassing module housing the membrane is arranged with flow fields for distributing the fluid flow throughout the membrane contact area. The distributed fluid flow may have a uniform membrane contact opportunity. 1. A fluid degassing apparatus , comprising: a first flow field configured to exert a first frictional flow restriction upon a fluid flow therethrough;', 'a second flow field including a plurality of channels extending between and fluidically connected to said first flow field, said channels being separated from one another by respective dividers, each of said channels being configured to exert a channel frictional flow restriction upon the fluid flow therethrough received from the first flow field, wherein said first frictional flow restriction is substantially less than a sum of said channel frictional flow restrictions., 'a module having a membrane disposed in a chamber and dividing said chamber into a permeate side and a retentate side, and said retentate side including2. A fluid degassing apparatus as in wherein the fluid flow has a uniform membrane contact opportunity.3. A fluid degassing apparatus as in wherein said uniform membrane contact opportunity includes contact between the fluid flow and an entirety of a surface of said membrane that is exposed to said retentate side of said chamber.4. A fluid degassing apparatus as in wherein said first flow field has a first flow depth that is greater than a second flow depth of said second flow field.5. A fluid degassing apparatus as in claim 1 , wherein each channel frictional flow restriction is substantially equal.6. A fluid degassing apparatus as in claim 5 , including a diffuser disposed in said chamber at said permeate side between said membrane and a chamber wall.7. A fluid degassing apparatus as in claim 6 , wherein said diffuser urges said membrane into ...

Deflector Disc of Disc Tube Membrane Module

The present invention discloses a deflector disc of a disc tube membrane module, including a deflector disc body, radial water distribution ribs, an inner support ring and an outer support ring. a first end and a second end of the radial water distribution rib are respectively fixedly connected with an inner edge of the deflector disc body and an outer edge of the inner support ring, an annular boss is arranged on the front side of the inner support ring, a seal ring groove is respectively arranged at corresponding positions of the front side and back side of the inner support ring multiple yielding water collecting grooves are annularly and uniformly distributed on the inner surface of the inner support ring and an inner edge of the outer support ring is fixedly connected with an outer edge of the deflector disc body.

Fabrication of hierarchical silica nanomembranes and uses thereof for solid phase extraction of nucleic acids

The present invention provides a novel method to fabricate silica nanostructures on thin polymer films based on silica deposition and self-wrinkling induced by thermal shrinkage. These micro- and nano-scale structures have vastly enlarged the specific area of silica, thus the silica nanomembranes can be used for solid phase extraction of nucleic acids. The inventive silica nanomembranes are suitable for nucleic acid purification and isolation and demonstrated better performance than commercial particles in terms of DNA recovery yield and integrity. In addition, the silica nanomembranes have extremely high nucleic acid capacity due to its significantly enlarged specific surface area of silica. Methods of use and devices comprising the silica nanomembranes are also provided.

Microfilter, manufacturing method and microfiltration unit

A microfilter, a manufacturing method thereof, and a microfiltration unit for holding the microfilter are provided. The microfilter has: a non-epoxy based microfilm; and a plurality of microholes provided on the surface of the non-epoxy based microfilm and penetrating therethrough via UV laser ablation, wherein the surface of the non-epoxy based microfilm is patterned into predetermined sections for locating isolated targets and quick enumeration.

DEVICE FOR DETERMINING THE PRESENCE OF A BACTERIOLOGICAL CONTAMINATION IN A FLUID

A device for determining contamination of a fluid by microorganisms has a housing with an internal volume, a cover closing the housing, a fluid inlet port, at least one filtration member, at least one nutrient layer including a composition of a microbiological culture medium, characterized in that the device includes a fluid outlet port, and in that the cover has an inner surface in the internal volume extending radially about the fluid inlet port up to a peripheral edge of the cover, said inner surface being inclined and converging towards the fluid inlet port, and in that the bottom of the housing has a surface extending radially about the fluid outlet port up to the side wall of the housing, said inner surface being inclined and converging towards the fluid outlet port. 2. The device as claimed in claim 1 , in which the inclination of the inner surface of the cover is strictly greater than 4°.3. The device as claimed in claim 1 , in which the inclination of the surface of the bottom is strictly less than 0°.4. The device as claimed in claim 1 , in which the fluid inlet port projects into the internal volume of the housing relative to the inner surface of the cover.5. The device as claimed in claim 1 , in which the filtration member is arranged in the housing at a given distance h from the inlet port claim 1 , the given distance h being strictly greater than 1 mm.6. The device as claimed in claim 1 , in which the housing has a first circumferential bearing surface shaped to cooperate complementarily with an edge of the cover.7. The device as claimed in claim 1 , in which the housing has at least one second bearing surface extending in the internal volume and shaped to receive a peripheral portion of the filtration member claim 1 , said second bearing surface being shaped to cooperate with a portion of the cover such that the peripheral portion of the filtration member is clamped between the cover and the housing.8. The device as claimed in claim 1 , in which the ...

MEMBRANE SEPARATION APPARATUS

A membrane separation apparatus includes: a lower support body that includes a water-to-be-treated introduction port and a concentrated water discharge port; an upper support body that includes a permeated water discharge port; a separation membrane that is provided between the lower support body and the upper support body, and that separates water to be treated into permeated water and concentrated water; and a first sheet-like elastic member that is provided between the separation membrane and the lower support body, and that forms seals between the separation membrane and the lower support body and between the lower support body and the upper support body. 1. A membrane separation apparatus , comprising:a lower support body comprising a water-to-be-treated introduction port and a concentrated water discharge port;an upper support body comprising a permeated water discharge port;a separation membrane that is provided between the lower support body and the upper support body, and that separates water to be treated into permeated water and concentrated water;a first sheet-like elastic member that is provided between the separation membrane and the lower support body, and that forms a seal between the separation membrane and the lower support body and between the lower support body and the upper support body; anda second sheet-like elastic member that is provided between the upper support body and the separation membrane, and that forms a seal between the upper support body and the lower support body.2. (canceled)3. The membrane separation apparatus according to claim 1 , whereinthe first sheet-like elastic member and the second sheet-like elastic member are arranged to cover a corner portion of a part of an opening of the lower support body in a sectional view.4. The membrane separation apparatus according to claim 1 , wherein the lower support body further comprises:a water-to-be-treated introduction portion comprising the water-to-be-treated introduction port and ...

Low Resistance Microfabricated Filter

The present technology provides micro fabricated filtration devices, methods of making such devices, and uses for microfabricated filtration devices. The devices may allow diffusion to occur between two fluids with improved transport resistance characteristics as compared to conventional filtration devices. The devices may include a compound structure that includes a porous membrane overlying a support structure. The support structure may define a cavity and a plurality of recesses formed in a way that can allow modified convective flow of a first fluid to provide improved diffusive transport between the first fluid and a second fluid through the membrane. 121.-. (canceled)22. A method of making a microfabricated filtration device , the method comprising:depositing a dielectric layer over a semiconductor substrate;forming a first layer of a membrane material on the dielectric layer and etching a pattern in the first membrane material layer;forming a sacrificial dielectric layer over the patterned first membrane material layer and forming a second membrane material layer over the sacrificial dielectric layer;forming a protective layer over the second membrane material layer;etching the substrate with a first etchant process that produces a cavity that does not extend to the layers of membrane material;etching the substrate with a second etchant process that forms a plurality of recesses through the remaining portion of the substrate and through the dielectric layer; andetching the filtration device with a third etchant process that removes the sacrificial dielectric layer forming pores through the membrane material layers, which provides access to the recesses such that the combination of the pores, recesses, and the cavity produce apertures through the filtration device.23. The method of claim 22 , wherein the first etchant process comprises a wet etchant.24. The method of claim 23 , wherein the first etchant process is anisotropic.25. The method of claim 23 , ...

HYDROGEN GENERATION ASSEMBLIES AND HYDROGEN PURIFICATION DEVICES

Hydrogen generation assemblies, hydrogen purification devices, and their components are disclosed. In some embodiments, the devices may include a permeate frame with a membrane support structure having first and second membrane support plates that are free from perforations and that include a plurality of microgrooves configured to provide flow channels for at least part of the permeate stream. In some embodiments, the assemblies may include a return conduit fluidly connecting a buffer tank and a reformate conduit, a return valve assembly configured to manage flow in the return conduit, and a control assembly configured to operate a fuel processing assembly between run and standby modes based, at least in part, on detected pressure in the buffer tank and configured to direct the return valve assembly to allow product hydrogen stream to flow from the buffer tank to the reformate conduit when the fuel processing assembly is in the standby mode. 1. A hydrogen purification device , comprising: an input port configured to receive a mixed gas stream containing hydrogen gas and other gases;', 'an output port configured to receive a permeate stream containing at least one of a greater concentration of hydrogen gas and a lower concentration of the other gases than the mixed gas stream; and', 'a byproduct port configured to receive a byproduct stream containing at least a substantial portion of the other gases;, 'first and second end frames includingat least one hydrogen-selective membrane disposed between and secured to the first and second end frames, the at least one hydrogen-selective membrane having a feed side and a permeate side, at least part of the permeate stream being formed from the portion of the mixed gas stream that passes from the feed side to the permeate side, with the remaining portion of the mixed gas stream, which remains on the feed side, forming at least part of the byproduct stream; and a perimeter shell,', 'an output conduit formed on the perimeter ...

HYDROGEN GENERATION ASSEMBLIES

Hydrogen generation assemblies and methods of generating hydrogen are disclosed. In some embodiments, the method may include receiving a feed stream in a fuel processing assembly of the hydrogen generation assembly; and generating a product hydrogen stream in the fuel processing assembly from the received feed stream. Generating a product hydrogen stream may, in some embodiments, include generating an output stream in a hydrogen generating region from the received feed stream, and generating the product hydrogen stream in a purification region from the output stream. The method may additionally include receiving the generated product hydrogen stream in a buffer tank of the hydrogen generation assembly; and detecting pressure in the buffer tank via a tank sensor assembly. The method may further include stopping generation of the product hydrogen stream in the fuel processing assembly when the detected pressure in the buffer tank is above a predetermined maximum pressure. 1. A hydrogen generation assembly , comprising:a fuel processing assembly configured to receive a feed stream and produce a product hydrogen stream from the feed stream;a pressurized gas assembly configured to receive at least one container of pressurized gas that is configured to purge the fuel processing assembly;a purge conduit configured to fluidly connect the pressurized gas assembly and the fuel processing assembly; anda purge valve assembly configured to allow the at least one pressurized gas to flow through the purge conduit from the pressurized gas assembly to the fuel processing assembly when power to the fuel processing assembly is interrupted.2. The assembly of claim 1 , wherein the purge valve assembly includes a purge valve that moves between a closed position in which the at least one pressurized gas does not flow through the purge conduit from the pressurized gas assembly claim 1 , and an open position in which the at least one pressurized gas is allowed to flow through the purge ...

MEMBRANE STRUCTURE BODY HAVING MATRIX STRUCTURE AND BIOMOLECULE FILTER USING SAME

A membrane structure body having a matrix structure and a biomolecule filter using the same are disclosed. The membrane structure body having a matrix structure, according to one embodiment of the present disclosure, comprises: a filtering part which includes a window region in which a plurality of window cells are formed in a matrix shape and a blocking region in which the window cells are not formed, and which filters biomolecules from a sample moving along the window region; and a support part extending from the filtering part so as to support the filtering part, wherein each of the window cells formed in the window region of the filtering part has have micro-holes allowing the biomolecules having a predetermined size or less to pass therethrough 1. A membrane structure having a matrix structure for filtering biomolecules included in a sample , comprising:a filtering part, which comprises a window region in which a plurality of window cells are formed in a matrix shape; and a blocking region in which the window cells are not formed, and which filters biomolecules from a sample moving along the window region; anda support part, which extends from the filtering part so as to support the filtering part,wherein each of the window cells formed in the window region of the filtering part has micro-holes allowing the biomolecules having a predetermined size or less to pass therethrough.2. The membrane structure of claim 1 , wherein the filtering part comprises a plurality of window regions claim 1 , and the plurality of window regions are configured to be placed side by side by being spaced apart one after the other with the blocking region placed therebetween.3. The membrane structure of claim 1 , wherein the membrane structure has a matrix structure having a laminated structure claim 1 , comprising:a substrate on which through holes constituting the window cells are formed; anda porous membrane which is laminated on the substrate and covers one side opening of the ...

ACIDIC GAS SEPARATION LAMINATE AND ACIDIC GAS SEPARATION MODULE PROVIDED WITH LAMINATE

An acidic gas separation laminate including: a porous support formed by laminating a porous film and an auxiliary support film; an acidic gas separation facilitated transport film; a permeating gas channel member; a sealing unit which is formed by impregnating the porous film, the auxiliary support film, and the gas channel member with an adhesive in the lamination direction thereof along the peripheral edge at a width of 5 mm or greater such that the permeation rate becomes 60% or greater; and a stress buffer unit which is adjacent to the sealing unit, has a permeation rate of the adhesive of less than 60% at least in the porous film, and is formed by impregnating at least the gas channel member with the adhesive. 1. An acidic gas separation laminate comprising:a composite film formed of a porous support which is formed by laminating a porous film and an auxiliary support film, a carrier which is disposed on the porous film side of the porous support and reacts with acidic gas in raw material gas, and an acidic gas separation facilitated transport film which contains a hydrophilic compound carrying the carrier;a permeating gas channel member which is laminated so as to face the auxiliary support film of the porous support and in which acidic gas has permeated through the composite film flows;a sealing unit which is formed by impregnating the porous film with an adhesive along the peripheral edge of the acidic gas separation laminate at a width of 5 mm or greater such that the impregnation rate becomes 60% or greater and impregnating the auxiliary support film and the gas channel member with the adhesive such that the impregnation rate becomes 60% or greater respectively; anda stress buffer unit which is adjacent to the sealing unit, has an impregnation rate of the adhesive of less than 60% at least in the porous film, and formed by impregnating at least the gas channel member with the adhesive.2. The acidic gas separation laminate according to claim 1 , wherein the ...

A SENSOR

A sensor for the in situ detection of a target chemical species, comprising a gas permeable membrane having a sampling side and an opposing analytical side, wherein the sampling side of the membrane is capable of receiving a sample and the membrane is permeable to target chemical species present in the sample. A weak acid or a weak base is in contact with the analytical side of the membrane, and a conductivity detector is in contact with the weak acid or weak base. In use, target chemical species present in the sample permeate through the membrane and react with the weak acid or weak base, producing ionic species and changing the conductivity. 1. A sensor for in situ detection of a target chemical species , the sensor comprising:a gas permeable membrane having a sampling side and an opposing analytical side, wherein the sampling side of the membrane is capable of receiving a sample and the membrane is permeable to target chemical species present in the sample;a weak acid or a weak base in contact with the analytical side of the membrane;a conductivity detector for measuring the conductivity on the analytical side of the membrane;wherein target chemical species present in the sample passes through the membrane and reacts with the weak acid or the weak base thereby generating ionic species, the ionic species acting to change the conductivity at the analytical side of the membrane.2. The sensor according to claim 1 , wherein claim 1 , prior to use of the sensor claim 1 , the weak acid or weak base has an conductivity of at most about 500 μS cm.3. The sensor according to claim 2 , wherein the weak acid is disposed on the analytical side of the membrane and includes boric acid.4. The sensor according to claim 3 , wherein the gas permeable membrane is a hydrophobic polytetrafluoroethylene (“PTFE”) membrane.5. A sensor for in situ detection of a free ammonia claim 3 , the sensor comprising:a gas permeable hydrophobic PTFE membrane having a sampling side and an opposing ...

Fixed tube of nucleic acid extraction component, and nucleic acid extraction component

A fixed tube of a nucleic acid extraction component and a nucleic acid extraction component. The nucleic acid extraction component includes a membrane column, which is fitted over the fixed tube. The fixed tube has a tube body, a tube opening, and a bottom. The tube body extends along a first direction. The end of the tube opening distal from the tube body has a protrusion which protrudes along a second direction, the first direction being vertical to the second direction. The bottom and the tube opening are respectively connected to two opposite sides of the tube body. The bottom has a shoulder and the shoulder of the bottom is connected to the membrane column.

FILTRATION BASE FOR VACUUM DIAPHRAGM FILTRATION

A filtration base for vacuum membrane filtration applications comprises a membrane bearing area on the upper side of the filtration base, which has a bearing structure and a supporting contour surrounding the bearing structure for a membrane filter placed in the membrane bearing area. The supporting contour has at least one notch which is in flow connection with the bottom side of the membrane bearing area and which is arranged such that it is adapted to be selectively covered by a membrane filter placed in the membrane bearing area. 1. A filtration base for vacuum membrane filtration applications , comprising a membrane bearing area on an upper side of the filtration base , which has a bearing structure and a supporting contour surrounding the bearing structure for a membrane filter placed in the membrane bearing area ,characterized in that the supporting contour has at least one notch which is in flow connection with the bottom side of the membrane bearing area and which is arranged such that it is adapted to be selectively covered by a membrane filter placed in the membrane bearing area.2. The filtration base according to claim 1 , characterized in that the notch interrupts a circumferential edge between the bearing structure and the supporting contour.3. The filtration base according to claim 2 , characterized in that the notch is delimited in a sharp-edged manner.4. The filtration base according to claim 3 , characterized in that the notch extends into the supporting contour.5. The filtration base according to claim 1 , characterized in that the supporting contour on its outside adjoins a sealing face onto which the rim of the membrane filter can be pressed by a pouring funnel put onto the filtration base.6. The filtration base according to claim 5 , characterized in that the notch does not extend into the sealing face.7. The filtration base according to claim 5 , characterized in that the bearing structure and the sealing face are arranged offset to each other ...

FLUID TREATMENT ARRANGEMENTS AND METHODS OF MAKING FLUID TREATMENT ARRANGEMENTS

A fluid treatment arrangement may include a fluid treatment unit having a multilayer structure. The multilayer structure may include at least one feed layer, at least one permeate layer, and at least one layer of a permeable fluid treatment medium between the feed layer and the permeate layer. The fluid treatment unit may further include a thermoset which holds the layers together and forms at least a portion of a first end surface of the fluid treatment unit. The fluid treatment arrangement may also include a thermoplastic sheet which overlies the first end surface of the fluid treatment unit. The thermoset directly bonds to the thermoplastic sheet. 1. A fluid treatment arrangement comprising:a fluid treatment unit having a multilayer structure which includes a feed layer, a permeate layer, and a layer of permeable medium positioned between the feed layer and the permeate layer, wherein the permeable medium has a feed side fluidly communicating with the feed layer and a permeate side fluidly communicating with the permeate layer, the fluid treatment unit further including first and second opposite end surfaces and a thermoset which holds the layers of the multilayer structure together and which forms at least a portion of the first end surface, anda thermoplastic sheet which overlies the first end surface of the fluid treatment unit, the thermoset directly bonding to the thermoplastic sheet on the first end surface of the fluid treatment unit.2. The fluid treatment arrangement of wherein the thermoset extends along the periphery of the fluid treatment unit on the first end surface and the thermoset directly bonds to the thermoplastic sheet around the periphery of the fluid treatment unit on the first end surface.3. The fluid treatment arrangement of wherein one of the feed layer and the permeate layer forms a portion of the first end surface and wherein the thermoplastic sheet is not bonded to said one layer on the first end surface.4. The fluid treatment ...

Sample preparation device

A sample preparation device, preferably for sterility testing, comprising a manifold including one or more receptacles for filtration units and at least one inlet and/or outlet port. The receptacle(s) is/are respectively provided with one or more connectors for establishing a fluid connection with mating ports of the filtration units and media containers/vials upon insertion of the same into the respective receptacles. The connectors are in fluid communication with the inlet and outlet port(s) via channels defined in the manifold to allow a desired fluid transfer through the manifold.

Removable cassette for an apparatus for sampling nanoparticles present in an aerosol, and filtration assembly for such a casette

The invention relates to a filtration assembly (5) comprising an annular support (12) which comprises an annular step (13) having an apex on which a filter membrane (11) rests, and a cover (20) covering the annular support in order to hold a periphery of the membrane between the cover and the annular support. The cover comprises a ring (21) which fits around the step to trap the periphery of the membrane between the ring and the annular support, the ring being extended by a skirt (22) which extends as a projection from the ring to cover an external peripheral wall of the annular support and to exhibit an end face (23) which extends in continuity with a bearing face (24) of the annular support. The invention also relates to a removable cassette for an apparatus for sampling nanoparticles comprising such a filtration assembly.

Single Stage Filtration System and Method For Use with Blood Processing Systems

A reservoir for use with a blood collection system includes a housing defining a cavity and a single stage filter. The housing has an inlet for receiving fluid from a source and an outlet. The inlet is in fluid communication with the cavity. The single stage filter includes a filter membrane configured to filter the fluid entering the housing from the inlet, and a frame defining the structure of the single stage filter. The frame also supports the filter membrane within the housing, and has a wiper edge that seals against an inner wall of the housing.

APPARATUS FOR THE SEPARATION OF PLASMA

The invention relates to an apparatus for separating blood and at the same time an apparatus () for absorbing blood () and separating components such as blood plasma, as a sample liquid (), having a feed device () for receiving the blood (), a separating device () for separating blood components as the sample liquid (), a channel () which takes up the sample liquid () preferably exclusively by capillary forces and a fill device for filling the channel () with sample liquid () in an inlet or feed region () of the channel (), wherein the separating device (), particularly a membrane, is domed, more particularly convexly shaped and projects with the apex of the convex shape into the filling device in the direction of filling. 1119213215232321831815. An apparatus () for absorbing blood () and separating blood components , such as blood plasma , as a sample liquid () , having a feed device () for receiving the blood () , a separating device () for separating blood components as a sample liquid () , a channel () which preferably takes up the sample liquid () exclusively by capillary forces and a filling device for filling the channel () with sample liquid () in an inlet or feed region () of the channel () , characterised in that the lower boundary surface of the feed region () is domed in the direction of the separating device () , thereby reducing the capillary distance between the interface and the separating device.23201815. The apparatus according to claim 1 , characterised in that the base of the channel () or the base of the collecting chamber () in the feed region () is domed beyond the fixing plane of the separating device () claim 1 , so that the separating device is domed counter to the direction of filling.332018. The apparatus according to claim 1 , characterised in that the base of the channel () or the base of the collecting chamber () in the feed region () is domed in the form of a peg claim 1 , in particular is embossed.46734. The apparatus according to ...

Molecular weight filtration system and apparatus

A molecular filtration device and method of use capable of filtering and purifying molecules of a particular characteristic, wherein the amount of molecule to be filtered may be in the nanogram range and may be dispersed in a relatively large volume of solution. The resultant elution may include a substantially pure solution comprising the desired molecule.

CHROMATOGRAPHY MEMBRANES, DEVICES CONTAINING THEM, AND METHODS OF USE THEREOF

Described herein are fluid treatment devices for use in tangential flow filtration, comprising a housing unit and a composite material, wherein the composite material comprises: a support member comprising a plurality of pores extending through the support member; and a non-self-supporting macroporous cross-linked gel comprising macropores having an average size of 10 nm to 3000 nm, said macroporous gel being located in the pores of the support member. The invention also relates to a method of separating a substance from a fluid, comprising the step of placing the fluid in contact with an inventive device, thereby adsorbing or absorbing the substance to the composite material contained therein. 1. A fluid treatment device comprising: (a) an inlet and an outlet;', '(b) a fluid flow path between the inlet and the outlet; and', a support member comprising a plurality of pores extending through the support member; and', 'a non-self-supporting macroporous cross-linked gel comprising macropores having an average size of 10 nm to 3000 nm, said macroporous gel being located in the pores of the support member;', 'wherein:', 'the macroporous cross-linked gel is selected from the group consisting of N,N′-methylenebisacrylamide cross-linked copolymers and cross-linked polymers of isopropylacrylamide, dodecyl acrylate, ethyl acrylate, ethylene oxide, hydroxymethyl acrylate, n-butyl acrylate, N-(hydroxymethyl)acrylamide, N-methacryloylacrylamide, N-methyl-N-vinylacetamide, N,N-dimethylacrylamide, N-vinyl-pyrrolidone, octadecylacrylamide, octyl acrylate, propyl acrylate, stearyl acrylate, styrene, or vinyl alcohol, or a mixture thereof;', 'the cross-linked gel comprises functional groups, wherein said functional groups are Protein A;', 'said macropores of said macroporous cross-linked gel are smaller than said pores of said support member; and', 'the pores of the support member are substantially perpendicular to the fluid flow path and the retentate outlet is substantially ...

FILTRATION SYSTEM AND USE THEREOF

The invention relates to a filtration system for use in a method of determining the presence and/or amount of cells, for example, viable cells, in a liquid sample, and to methods of using and manufacturing such a filtration system. The filtration system includes a cup with an upper portion and a ring portion, where the ring portion is separably coupled to the upper portion. 1. A cell capture system for receiving a fluid sample , the system comprising: (i) an upper portion,', '(ii) a ring having a periphery, wherein the upper portion is separably coupled to the ring by a frangible connection comprising a circumferential groove that defines a parting plane between the upper portion and the ring so that the upper portion can be separated from the ring upon manual application by a user of a rotational force sufficient to break the frangible connection, and', '(iii) a fluid permeable membrane attached to the periphery to produce a fluidic seal between the membrane and the ring, wherein a portion of the membrane is adapted to retain cells thereon; and, '(a) a cup comprising(b) a base configured to receive the ring.2. The system of claim 1 , wherein the membrane portion (i) defines a plurality of pores having an average diameter less than about 1 μm so as to permit fluid to traverse the portion of the membrane while retaining cells thereon and (ii) is substantially non-autofluorescent when exposed to light having a wavelength in a range from about 350 nm to about 1000 nm.3. The system of claim 1 , wherein the membrane portion has a flatness tolerance of up to about 100 μm.4. The system of claim 1 , wherein the cup is adapted to direct a fluid claim 1 , when introduced into the upper portion claim 1 , toward the membrane portion.5. The system of claim 1 , wherein the ring is integrally formed with the upper portion.6. The system of claim 1 , wherein the frangible connection comprises a thin wall at an intersection of the upper portion and the ring.7. The system of claim 1 , ...

CYCLING ULTRA-THIN CHANNEL FILTRATION

A cycling ultra-thin channel filtration (cUTF) method, system and module are disclosed for concentration and purification of biomolecules. In one embodiment, a cUTF system includes a cUTF module and a cycle controller to load a feed aliquot of a feed stream into the cUTF module inducing permeation of the feed stream to build a boundary layer by pressurizing the feed stream, to stop permeation and to recover a retentate aliquot in a repeating cycle. 1. A cycling ultra-thin channel filtration (cUTF) system comprising a filtration membrane separating an interior of said cUTF module into a retentate compartment and a permeate compartment;', 'a feed port fluidly coupled to a first end of the retentate compartment;', 'a retentate port fluidly coupled to a second end of the retentate compartment;', 'a permeate port fluidly coupled to the permeate compartment;, 'a cUTF module comprisinga retentate valve coupled to the retentate port;a permeate pressurization valve coupled to the permeate port;a cycle controller controllably connected to the retentate valve and the permeate pressurization valve; a timing circuit to control the retentate valve and the permeate pressurization valve;', 'a load detector to control the retentate valve and the permeate pressurization valve; and', 'a recovery detector to control the retentate valve and the permeate pressurization valve., 'wherein the cycle controller includes at least one of2. The cUTF system of claim 1 , wherein the retentate compartment further comprises:an array of substantially similar channels having a feed end fluidly coupled to the feed port and a retentate end fluidly coupled to the retentate port;a plurality of feed distribution passageways in fluid communication with the feed end of the array of substantially similar channels; anda plurality of retentate distribution passageways in fluid communication with the retentate end of the array of substantially similar channels.3. The cUTF system of claim 2 , wherein each of the ...

CONTAINER FOR A FILTRATION ASSEMBLY

The invention relates to a container for a rack of a diagnostic robot comprising: —a container body comprising a sidewall or multiple sidewalls, a bottom and a top wherein the container body is of round, oval, square, rectangular, hexagonal or polygonal cross sectional shape, —the top is provided with an opening that matches the size and form of a filter membrane/supporting body of an object carrier which is placed over the opening in the top of the container for filtration of a sample, wherein the opening exhibits a rim and —the top is provided with a top-guiding-means which matches with a corresponding object-carrier-guiding-means on or in the object carrier so that the object carrier locks with a predetermined surface faced up into a predetermined position on the top and —the container is equipped with an adapter which matches a gas outlet on the rack. 112. A container () for a rack of a diagnostic robot comprising:{'b': 17', '18', '13', '17, 'a container body () comprising a sidewall or multiple sidewalls, a bottom () and a top () wherein the container body () is of round, oval, square, rectangular, hexagonal or polygonal cross sectional shape,'}{'b': 13', '14', '2', '3', '1', '14', '13', '14', '19, 'wherein the top () is provided with an opening () that matches the size and form of a filter membrane/supporting body (, ) of an object carrier () which is placed over the opening () in the top () of the container for filtration of a sample, wherein the opening () exhibits a rim (), and further'}{'b': 13', '20', '21', '1', '1', '13, 'wherein the top () is provided with a top-guiding-means () which matches with a corresponding object-carrier-guiding-means () on or in the object carrier () so that the object carrier () locks with a predetermined surface faced up into a predetermined position on the top () and further'}{'b': 12', '15', '16, 'wherein the container () is equipped with an adapter () which matches a gas outlet () on the rack.'}217. The container of claim 1 ...

CAPILLARY PRESSURE RE-SET MECHANISM AND APPLICATIONS

Many hand-held diagnostics are limited in their functionality due to the challenging physics associated with small dimensional systems. An example of this is capillary forces in hydrophilic systems, such as the tight retention of liquid passing through a small pore filtration membrane, or capillary force driven microfluidics where, to keep liquid flowing the dimensions of the system become so small that the flow rates are too low to be useful, or the manufacturing of such devices becomes uneconomical. This disclosure details methods to ‘reset’ the capillary force condition to avoid the requirement of transient pressure spikes associated with the breakthrough pressure of small pore membranes, and avoid the necessity of extremely small microfluidic channels, which can be useful in applications such as filtration of whole blood to plasma using only suction pressure or passive capillary pressure. 1. (canceled)2. A microchannel device comprising:a collection channel;a first microchannel connected to the collection channel and forming a first capillary stop junction between the first microchannel and the collection channel;one or more second microchannels connected to the collection channel and forming one or more second capillary stop junctions between the second microchannel and the collection channel, the one or more second capillary stop junctions being downstream of the first capillary stop junction; anda soluble matrix placed in the collection channel at the first capillary stop junction, the soluble matrix possessing a capillary drawing force sufficient to draw liquid from the first microchannel into the soluble matrix and at least partially dissolving or disintegrating in the liquid and thereby releasing the liquid into the collection channel, whereby a capillary barrier of the first stop junction is overcome, causing the liquid to flow along the collection channel and past the one or more second capillary stop junctions to thereby wet-through and overcome ...

FILTER MODULE

The present disclosure relates to a filter module for a medical fluid delivery system capable of removing cytokine inducing substances (CIS) from a medical fluid. 1. A single use filter module capable of on-line production of a medical fluid which is sterile , non-pyrogenic , and free from cytokine-inducing substances , comprising a1) a bottom part comprising a fluid compartment containing a support structure consisting of a plurality of longitudinal ribs and transversal ribs; and a fluid outlet positioned on the center line of the bottom part at one end of the fluid compartment;', 'a2) a top part comprising a fluid compartment containing a support structure consisting of a plurality of longitudinal ribs and transversal ribs; and a fluid inlet positioned on the center line of the top part on one end wall of the fluid compartment;, 'a) a housing comprised of'}b) a protection net arranged within the housing and located atop the longitudinal ribs of the bottom part;c) a positively charged microporous flat sheet membrane arranged within the housing and located atop the protection net; andd) a retention net arranged within the housing and located between the positively charged microporous flat sheet membrane and the longitudinal ribs of the top part.2. The module of claim 1 , wherein the height of the longitudinal ribs equals the depth of the fluid compartment; and the height of the transversal ribs is smaller than the height of the longitudinal ribs.3. The module of claim 1 , wherein the protection net is a net woven from PET monofilament.4. The module of claim 1 , wherein the protection net has a mesh opening between about 100 ym to about 600 ym.5. The module of claim 1 , wherein the positively charged microporous membrane comprises polyethersulfone; nylon 6 claim 1 ,6; or cellulose acetate.6. The module of claim 1 , wherein the positively charged microporous membrane has a pore size between about 200 nm to about 400 nm.7. The module of claim 1 , wherein the retention ...

HYDROGEN GENERATION ASSEMBLIES AND HYDROGEN PURIFICATION DEVICES

Hydrogen generation assemblies, hydrogen purification devices, and their components are disclosed. In some embodiments, the devices may include a permeate frame with a membrane support structure having first and second membrane support plates that are free from perforations and that include a plurality of microgrooves configured to provide flow channels for at least part of the permeate stream. In some embodiments, the assemblies may include a return conduit fluidly connecting a buffer tank and a reformate conduit, a return valve assembly configured to manage flow in the return conduit, and a control assembly configured to operate a fuel processing assembly between run and standby modes based, at least in part, on detected pressure in the buffer tank and configured to direct the return valve assembly to allow product hydrogen stream to flow from the buffer tank to the reformate conduit when the fuel processing assembly is in the standby mode. 1. A hydrogen purification device , comprising: an input port configured to receive a mixed gas stream containing hydrogen gas and other gases;', 'an output port configured to receive a permeate stream containing at least one of a greater concentration of hydrogen gas and a lower concentration of the other gases than the mixed gas stream; and', 'a byproduct port configured to receive a byproduct stream containing at least a substantial portion of the other gases;, 'first and second end frames includingat least one hydrogen-selective membrane disposed between and secured to the first and second end frames, the at least one hydrogen-selective membrane having a feed side and a permeate side, at least part of the permeate stream being formed from the portion of the mixed gas stream that passes from the feed side to the permeate side, with the remaining portion of the mixed gas stream, which remains on the feed side, forming at least part of the byproduct stream; and a perimeter shell,', 'an output conduit formed on the perimeter ...

MEMBRANE DEVICE FOR BLOOD SEPARATION AND METHODS OF MAKING AND USING THE SAME

Disclosed herein are membrane device embodiments that can be used for separating blood plasma and/or blood serum from blood samples. The membrane device embodiments comprise built-in features that facilitate blood plasma and/or blood serum separation and also provide the ability to detect, quantify, and qualify analytes present in a blood sample. The membrane device embodiments are portable and just a single membrane can be used for a plethora of detection and analysis techniques. Also disclosed herein are embodiments of methods for making and using the membrane device. 1. A membrane device , comprising:a membrane having a first surface and a second surface;a wicking region formed on the membrane, comprising a sample introduction region on the first surface of the membrane; a flow-through via that is directly and fluidly coupled to the sample introduction region and that directs fluid flow from the first surface of the membrane device to the second surface of the membrane; and a fluidic channel that is fluidly and proximally coupled to the flow-through via, wherein the fluidic channel is configured to direct fluid flow in a direction substantially perpendicular to a direction of fluid flow through the flow-through via;wherein the sample introduction region, the flow-through via, and the fluidic channel of the wicking portion are hydrophilic and are structurally defined by a first hydrophobic polymer.2. The membrane device of claim 1 , further comprising:a capillary flow region, comprising a capillary channel and a sample collection region, wherein the capillary channel is fluidly coupled to the sample collection region and further is fluidly coupled to the fluidic channel of the wicking region;wherein the capillary channel and the sample collection region are structurally defined by a second hydrophobic polymer having a concentration higher than the first hydrophobic polymer.3. The membrane device of claim 2 , wherein the capillary channel and the fluidic channel of ...

Filtration filter

A filtration filter comprises a porous film including a central film portion having a plurality of through holes and an outer edge portion adjacent to the central film portion. The porous film portion lies in a flat plane in the absence of a force being applied to the central portion of the central film portion. A frame holds the outer edge portion of the porous film in such a manner that when a force is applied to the central film portion in a first direction, the central film portion moves in the first direction relative to the flat plane and the outer edge portion moves in a second direction, opposite to the first direction, relative to the flat plane. In this way stresses applied to the porous film during a filtering operation are reduced.

FILTRATION ASSEMBLY AND METHOD FOR MICROBIOLOGICAL TESTING

The invention concerns a filtration assembly for microbiological testing and a method of using the filtration assembly for that purpose. The filtration assembly () comprises a ring-like membrane support () holding a filtration membrane (), a cylindrical reservoir () of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support () to define a sample volume adjacent to the filtration membrane () on one axial side of the membrane support (); and a lid device () removably and fluid tightly attachable to the other axial opening of the reservoir () to close the opening. Further, the lid device () is removably and fluid tightly attachable to the membrane support () so as to seal the one axial side of the membrane support () from the environment. 11. A filtration assembly () for microbiological testing , comprising:{'b': 10', '11, 'a ring-like membrane support () holding a filtration membrane ();'}{'b': 20', '10', '11', '10, 'a cylindrical reservoir () of which opposite axial ends have openings and one axial opening is removably and fluid-tightly attachable to the membrane support () to define a sample volume adjacent to the filtration membrane () on one axial side of the membrane support (); and'}{'b': 40', '20', '40', '10', '10, 'a lid device () removably and fluid tightly attachable to the other axial opening of the reservoir () to close the opening, wherein the lid device () is removably and fluid tightly attachable to the membrane support () so as to seal the one axial side of the membrane support () from the environment.'}2140414040a. The filtration assembly () according to claim 1 , wherein the lid device () has a hinge () for supporting a lid portion () so as to allow selective opening of the lid device () with a predefined movement.314140. The filtration assembly () according to claim 2 , wherein the hinge () is included in the lid device ().414120104140. The filtration assembly () according to ...

HIGH-PERFORMANCE, LOW-STRESS SUPPORT STRUCTURE WITH MEMBRANE

A support structure for a membrane comprises a plurality of support members and at least one flange, including: (a) a first set of spoke-like support members that extend generally from at least one flange toward a common hub and that have a distal end joined to at least one flange and a proximal end joined to the common hub; and (b) at least one subsequent set of spoke-like support members that are distributed between circumferentially adjacent pairs of spoke-like support members from the prior sets and that extend generally from at least one flange toward the hub, each having a distal end joined to at least one flange and a proximal end connected to the nearest circumferentially adjacent pair of spoke-like support members from the prior sets via a pair of approximately straight anchoring support members which join together and form an angular joint at or near said proximal end, with the vertex of said angular joint pointing generally away from the hub. 1. A support structure for a membrane , said support structure comprising a plurality of support members and at least one flange , said plurality of support members comprising a plurality of sets of spoke-like support members including: (i) a distal end located farther from the hub and joined directly or indirectly to at least one flange; and', '(ii) a proximal end located nearer the hub and joined directly or indirectly to the proximal end of each other spoke-like support member of this first set;, '(a) a first set comprising a plurality of spoke-like support members that extend generally from at least one flange toward a common hub, each spoke-like support member of this first set comprising (i) a distal end located farther from the hub and joined directly or indirectly to at least one flange; and', '(ii) a proximal end located nearer the hub and connected to the nearest circumferentially adjacent pair of spoke-like support members from the prior sets via a pair of substantially straight anchoring support members, ...

DIALYSIS CELL FOR SAMPLE PREPARATION FOR A CHEMICAL ANALYSIS METHOD

The invention relates to a dialysis cell for sample preparation for a chemical analysis method, in particular for ion chromatography. The dialysis cell comprises a donor channel and an acceptor channel extending parallel thereto. The donor channel and the acceptor channel are separated from each other by a selectively permeable dialysis membrane. In particular, an analyte that is dissolved in a donor solution in the donor channel can enter through the dialysis membrane into the acceptor solution in the acceptor channel. The acceptor channel has at least in some sections a volume that is smaller than the volume of the donor channel extending parallel thereto. Acceptor and donor channels are formed from half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are designed in each case as a recess in a contact surface of one of the half-cells with the dialysis membrane. 120-. (canceled)21. A dialysis cell for sample preparation for a chemical analytical method comprising:a donor channel; anda parallelly running acceptor channel,wherein, when used as intended, the donor channel and the acceptor channel are separated from one another by a selectively permeable dialysis membrane,{'sub': A', 'D, 'wherein the acceptor channel has, at least sectionally, a volume Vwhich is smaller than a parallelly running volume Vof the donor channel;'}wherein the dialysis cell comprises two half-cells, between which the dialysis membrane is arranged, wherein the donor channel and the acceptor channel are formed as, in each case, an indentation in a contact surface of one of the half-cells with the dialysis membrane.22. The dialysis cell as claimed in claim 21 , wherein the acceptor channel has claim 21 , on at least 50% of its length a volume Vwhich is smaller than a parallelly running volume Vof the donor channel.23. The dialysis cell as claimed in claim 22 , wherein the acceptor channel has claim 22 , on its entire length claim 22 , a ...

FILTRATION DEVICE, FILTRATION SYSTEM, AND FILTRATION METHOD

Provided is a filtration device including: a flow path that meanders; a filtration membrane that separates a supply side and a permeation side of the flow path; a first distribution port that is provided at one end of the supply side of the flow path; a second distribution port that is provided at the other end of the supply side of the flow path; a first discharge port that is provided on the permeation side of the flow path; and a second discharge port that is provided at a position different from that of the first discharge port on the permeation side of the flow path. First liquid feeding for allowing a liquid flowed in from the first distribution port to flow out from the second distribution port, and second liquid feeding for allowing a liquid flowed in from the second distribution port to flow out from the first distribution port are alternately performed. A liquid that has passed through the filtration membrane is discharged from the first discharge port while the first liquid feeding is performed, and a liquid that has passed through the filtration membrane is discharged from the second discharge port while the second liquid feeding is performed. 1. A filtration device comprising:a flow path that meanders;a filtration membrane that separates a supply side and a permeation side of the flow path;a first distribution port that is provided at one end of the supply side of the flow path;a second distribution port that is provided at another end of the supply side of the flow path;a first discharge port that is provided on the permeation side of the flow path;a second discharge port that is provided, at a position different from that of the first discharge port, on the permeation side of the flow path;a first open/close valve that is capable of switching the first discharge port between an open state and a closed state; anda second open/close valve that is capable of switching the second discharge port between an open state and a closed state,wherein, when one of ...

FILTRATION FILTER

A filtration filter is suitable for performing cross-flow filtration by using a metallic porous membrane. A metallic porous membrane has a membrane portion for filtering filtration objects contained in a fluid and a held portion provided at its outer periphery. A first frame member and a second frame member hold the held portion of the metallic porous membrane there between. The held portion has a bent portion bent to a second principal surface side opposing a first principal surface of the membrane portion. The first frame member is in contact with the held portion at the first principal surface side of the metallic porous membrane. The second frame member is disposed at an inner side portion of the first frame member and is in contact with the held portion at the second principal surface side of the metallic porous membrane. 1. A filtration filter , comprising:(a) a metallic porous membrane having a center and including:(i) upper and lower opposed main surfaces;(ii) an inner membrane portion for filtering objects contained in a fluid, the inner membrane portion extending outwardly from the center of the metallic porous membrane and lying in a plane; and(iii) a held portion extending outwardly from an outer periphery of the inner membrane portion;(b) a lower frame having a bottom surface and a first edge; and(c) an upper frame having a second edge which is located inward of and below the first edge of the lower frame, the held portion being held by the upper and lower frames and being bent around the first and second edges in a zig zag manner, the bottom surface of the lower frame being substantially coplanar with a lower main surface of the inner membrane portion of the metallic porous membrane.2. The filtration filter of claim 1 , wherein the first edge is formed between first and second surfaces of the lower frame and the second edge is formed between first and second surfaces of the upper frame.3. The filtration filter of claim 2 , wherein:the first surfaces of ...

METHOD FOR ATTACHING WATER-REPELLENT FILTER TO INLET OR OUTLET OF AIR VENT FORMED IN THERMOPLASTIC RESIN MOLDED ARTICLE, THERMALLY PROCESSING TIP AND THERMALLY WELDING TIP FOR MOLDING FILTER ATTACHMENT PORTION AND FOR ATTACHING FILTER, AND MOLDED ARTICLE

A method attaches a liquid-repellent filter to an air vent of a resin molded article accommodating a component/electronic part. A thermal processing tip and a thermally welding tip and a molded article are provided. The thermal processing tip () forms a filter attachment surface () at the inlet or outlet of an air vent () in a thermoplastic resin molded article (). A filter fixing rib () is formed around the attachment surface. The porous filter () is dropped onto the filter attachment surface, and a thermal welding tip () is used to melt the filter fixing rib such that the melted resin flows onto and covers a circumferential edge portion of the filter, penetrating the body of the filter. The melted resin penetrating the filter and covering the circumferential edge portion of the filter are cooled to solid, whereby the filter is fixed to the filter attachment surface. 1. A method for installing a filter on an inlet or outlet of a ventilation hole formed on a thermoplastic resin molded article , the method comprising the steps of:forming, with a thermal processing tip, a filter installation surface on the inlet or outlet of the ventilation hole formed on the thermoplastic resin molded article;providing the thermal processing tip with a construction in which a guiding portion is formed at a center of a top of the main body of the tip, the guiding portion being inserted into the inlet or outlet of the ventilation hole formed on the thermoplastic resin molded article during the step of forming, while a pressing heating surface is formed around the base part of the guiding portion, and a flange is further formed on an outer circumference of the heating pressing surface at a position slightly set back and to form the filter installation surface using the thermal processing tip, the guiding portion is inserted into the inlet or outlet of the ventilation hole on the thermoplastic resin molded article, with the thermal processing tip being heated electrically and pressed to ...

Sample Preparation Device and Methods of Use

A device for isolating DNA from a sample containing cells, including a cartridge having an entrance port and an exit port, a membrane disposed between the entrance port and the exit port, and a plurality of channels between the membrane and the exit port. Additionally, systems and methods for isolating DNA from a sample containing cells and also systems and methods for amplifying and isolating single-stranded DNA from a sample containing DNA.

Instruments, modules, and methods for improved detection of edited sequences in live cells

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.

Systems for Utilizing Crossflow Filtration for Cell Enrichment

A disposable cell enrichment kit includes a crossflow filtration device configured to be disposed along a main loop pathway and to receive a process volume containing a biological sample and utilize crossflow filtration, via a micro-porous membrane, to retain a specific cell population in a retentate from the process volume and to remove a permeate including certain biological components from the process volume. The crossflow filtration device includes a laminated filtration unit that includes the micro-porous membrane, a first mating portion, a second mating portion, and a membrane support. The membrane support includes a first plurality of structural features that define a first plurality of openings, wherein the first plurality of structural features are coupled to the micro-porous membrane and provide support to the micro-porous membrane, and the first plurality of openings allow the permeate to flow through them after crossing the micro-porous membrane.

Apparatus And Method For Filtration Of A Suspension

The present invention provides devices suitable for filtration including diafiltration of a suspension containing a species such as particles, cells or macromolecules, apparatus comprising such devices and methods of using the devices and apparatus. The devices of the invention comprise a vessel having a filter that divides the vessel into a first chamber and a second chamber provided with various outlet ports. Gas is used to finally concentrate the suspension () in the filtration chamber by displacing the liquid up to 95% through the filter (). 1. A device for filtration of a liquid containing a species in suspension comprising a vessel , the vessel comprising a filter that divides the vessel into a first chamber and a second chamber , the first chamber comprising a first region and a second region wherein the second region is above the first region , the vessel being provided with:(i) a lower port opening to the first region of the first chamber, configured to permit exit of a liquid containing the species from the first chamber,(ii) an upper port opening to the second region of the first chamber, and(iii) an outlet port opening to the second chamber.2. A device according to wherein a lower port is configured to receive a liquid containing the species.3. A device according to wherein an upper port is configured to receive a liquid containing the species.4. Apparatus for filtration of a liquid containing a species in suspension comprising:A filter device comprising a vessel, the vessel comprising a filter that divides the vessel into a first chamber and a second chamber, the first chamber comprising a first region distal to a first end of the filter and a second region proximal to the said first end of the filter, the vessel being provided with:(i) a first port opening to the first region of the chamber, the first port being configured to receive a liquid containing the species and further configured to permit exit of the liquid containing the species from the ...

Hybrid irrigation tubing

Features of relatively low pressure microporous (and preferably plant-responsive) irrigation tubes are combined with features of relatively high pressure drip emitter tubes to produce a hybrid irrigation tube. Methods for using and manufacturing the hybrid irrigation tube are also disclosed.

HEATING DEVICE FOR A FILTRATION ASSEMBLY

The invention relates to a heating device for a rack of a diagnose robot comprising: -a polygonal, oval or cylindrical ring () defining a polygonal, oval or cylindrical closed wall, having a bottom opening () and a top opening () -wherein the bottom opening matches the size and form of a filter membrane and/or supporting body () of a carrier () of a filtration assembly; and -one or more heating elements () selected from -a heating element which is integrated into the ring, -a heating element which is arranged on the outer and/or inner surface of the wall defining the ring, and -a heating element arranged in or on a lid, wherein the lid matches the size and form of the opening of the ring. 1. A heating device for a rack of a diagnose robot comprising:{'b': 221', '222', '223, 'a polygonal, oval or cylindrical ring () defining a polygonal, oval or cylindrical closed wall, having a bottom opening () and a top opening ()'}{'b': 2', '3', '1, 'wherein the bottom opening matches the size and form of a filter membrane and/or supporting body (, ) of a carrier () of a filtration assembly; and'}{'b': '224', 'claim-text': a heating element which is integrated into the ring,', 'a heating element which is arranged on the outer and/or inner surface of the wall defining the ring, and', 'a heating element arranged in or on a lid, wherein the lid matches the size and form of the top opening of the ring., 'one or more heating elements () selected from'}2221. The heating device of claim 1 , wherein the ring () is made of polyethylene claim 1 , polypropylene claim 1 , polyamide claim 1 , polycarbonate claim 1 , polystyrene or glass or ceramic or metal.322422. The heating device of claim 1 , wherein the heating element () is integrated in a funnel/fixture ().4224. The heating device of claim 1 , wherein the heating element () is an electrical heating element where heat (infrared radiation (IR)) is generated by an electrical current flowing through a metal wire claim 1 , mesh claim 1 , ...

HEMOFILTRATION DEVICE

A hemofiltration device capable of surely performing highly-efficient hemofiltration. The hemofiltration device of the present invention is adapted to be implanted in a mammalian body for filtering blood, and includes a blood flow path layer having a blood flow path, a filtrate flow path layer having a filtrate flow path disposed along the blood flow path, and a filtration membrane interposed between the blood flow path layer and the filtrate flow path layer, for filtering the blood flowing through the blood flow path. A filtrate outlet of the filtrate flow path is provided at a position closer to a blood outlet than to a blood inlet of the blood flow path. The blood inlet, blood outlet, and filtrate outlet are provided only on one side or separately on opposite sides of a main body portion in the direction in which the layers are stacked. 1. A hemofiltration device adapted to be implanted in a body of a mammal for filtering blood , comprising:a blood flow path layer having a blood flow path;a filtrate flow path layer having a filtrate flow path disposed along the blood flow path; anda filtration membrane interposed between the blood flow path layer and the filtrate flow path layer, the filtration membrane being adapted to filter blood flowing through the blood flow path,wherein a filtrate outlet of the filtrate flow path is provided at a position closer to a blood outlet of the blood flow path than to a blood inlet of the blood flow path.2. The hemofiltration device according to claim 1 , further comprising a main body portion having the blood flow path layer and the filtrate flow path layer alternately stacked with the filtration membrane interposed therebetween claim 1 ,wherein the blood inlet, the blood outlet, and the filtrate outlet are provided only on one side or separately on opposite sides of the main body portion in a direction in which the layers are stacked.3. The hemofiltration device according to claim 2 , wherein the main body portion has a ...

HYDROGEN GENERATION ASSEMBLIES

Hydrogen generation assemblies and methods of generating hydrogen are disclosed. In some embodiments, the method may include receiving a feed stream in a fuel processing assembly of the hydrogen generation assembly; and generating a product hydrogen stream in the fuel processing assembly from the received feed stream. Generating a product hydrogen stream may, in some embodiments, include generating an output stream in a hydrogen generating region from the received feed stream, and generating the product hydrogen stream in a purification region from the output stream. The method may additionally include receiving the generated product hydrogen stream in a buffer tank of the hydrogen generation assembly; and detecting pressure in the buffer tank via a tank sensor assembly. The method may further include stopping generation of the product hydrogen stream in the fuel processing assembly when the detected pressure in the buffer tank is above a predetermined maximum pressure. 1. A hydrogen generation assembly , comprising:a fuel processing assembly configured to receive a feed stream and produce a product hydrogen stream from the feed stream; a feed tank configured to contain feedstock for the feed stream,', 'a feed conduit fluidly connecting the feed tank and the fuel processing assembly, and', 'a pump configured to deliver the feed stream at a plurality of flowrates to the fuel processing assembly via the feed conduit; and, 'a feed assembly configured to deliver the feed stream to the fuel processing assembly, the feed assembly including a feed sensor assembly configured to detect pressure in the feed conduit downstream from the pump, and', 'a pump controller configured to select a flowrate from the plurality of flowrates based on the detected pressure in the feed conduit, and to operate the pump at the selected flowrate., 'a control system, including2. The assembly of claim 1 , wherein the pump controller is further configured to select the flowrate based solely on the ...

SUPPORT APPARATUS FOR A FILTER MEMBRANE AND DISC-SHAPED POROUS SUPPORT MEMBER FOR A FILTER MEMBRANE

A support apparatus for a filter membrane comprises a base support and a disc-shaped porous support member. The member is removably received in a seat portion of the base support in fluid communication with a drain. A bottom side of the disc-shaped porous support member is supported in a support plane. The bottom side of the member is unsupported in an area and the unsupported area is adjacent to a space in the seat portion of the base support that is located and dimensioned such that application of a force, onto the top side of the member at a location substantially within the boundaries of the unsupported area at the bottom side will cause the member to pivot/tilt into the space and lift above the support plane at a diagonally opposite side from the location where the force is applied so that it can be easily grasped and removed. 1. A support apparatus for a filter membrane , comprisinga base support and a disc-shaped porous support member for the filter membrane, wherein said disc-shaped porous support member is removably received in a seat portion of said base support in fluid communication with a drain such that a bottom side of the disc-shaped porous support member is supported in a support plane,wherein the bottom side of the disc-shaped porous support member is unsupported in an area and the unsupported area is adjacent to a space in the seat portion of the base support that is located and dimensioned such that application of a force onto the top side of the disc-shaped porous support member at a location within the boundaries of the unsupported area will cause the disc-shaped porous support member to pivot/tilt into the space and lift up above the support plane at a diagonally opposite side from said location.2. The support apparatus for a filter membrane according to claim 1 , wherein the support plane is defined by a discontinuous seat face including plural spaced apart seat points or seat portions or by a continuous seat face.3. The support apparatus for ...

FILTER MODULE AND METHOD FOR DETECTING MICROORGANISMS

A filter module () has a housing () which is subdivided by a membrane filter () into an inlet chamber (), which is connected to an inlet connecting piece () arranged rigidly on the housing (), and an outlet chamber (), which has a filtrate outlet (). The inlet connecting piece has two connectors, specifically a first connector () and a second connector (), which connect selectively and fluidically to the inlet chamber with a 3-way valve () integrated into the inlet connecting piece. The valve has a first entry, which is connected to the first connector, a second entry, which is connected to the second connector, and an exit, which is connected to the inlet chamber. The first connector is configured as an adapter for outwardly sealed coupling of a culture medium bottle (), which coupling permits a gravity-driven exchange of liquid with the first entry of the valve. 1. A filter module comprising:a housing which is subdivided by a membrane filter into an inlet chamber, which is connected to an inlet connecting piece arranged rigidly on the housing, and an outlet chamber, which has a filtrate outlet, anda 3-way valve integrated into the inlet connecting piece,wherein the inlet connecting piece has a first connector and a second connector, which are configured to connect fluidically and selectively to the inlet chamber with the 3-way valve, wherein the 3-way valve comprises a first entry, which is connected to the first connector, a second entry, which is connected to the second connector, and an exit, which is connected to the inlet chamber, andwherein the first connector comprises an adapter configured to seal outwardly to a culture medium bottle through a coupling, which coupling provides a gravity-driven exchange of liquid with the first entry of the 3-way valve.2. The filter module as claimed in claim 1 ,wherein the first connector and the second connector are each configured to connect individually fluidically to the inlet chamber.3. The filter module as claimed in ...

MEMBRANE SEPARATION APPARATUS

A membrane separation apparatus includes: a shell, wherein an inner surface of the shell is an arc surface, and at least one medium inlet and at least one medium outlet used for discharging a medium that is separated are arranged on the shell; a rotor arranged inside the shell, wherein at least two contact ends that are always in slidably contact with the inner surface of the shell are arranged on an outer surface of the rotor, the outer surface of the rotor and the inner surface of the shell form sealed separate cavities between the adjacent contact ends, and an empty part inside the rotor is used as a medium storage chamber; and separation chambers arranged inside the rotor. 110-. (canceled)11. A membrane separation device , comprising:a housing having an arc-shaped inner surface, the housing being provided with at least one medium inlet and at least one medium outlet used for discharging a separated medium;a rotor provided in the housing, the rotor being provided with at least two contact ends on an outer surface thereof, the at least two contact ends being constantly in sliding contact with the inner surface of the housing, the outer surface of the rotor and the inner surface of the housing forming sealed separate cavities between adjacent contact ends, the separate cavities being separated by the contact ends, an inside of the rotor being hollow, and a hollow part inside the rotor being used as a medium storage chamber; andseparation chambers provided inside the rotor as a part of the rotor, one of the separation chambers being defined between the adjacent contact ends, each of the separation chambers being provided with a membrane therein for dividing the separation chambers into two parts, one inner part and one outer part, one-way valves corresponding to the separate cavities being provided on outer walls of the separation chambers for communicating with the separate cavities, medium outlets corresponding to the medium storage chamber being provided on inner ...

METHOD AND SOLAR-BASED SYSTEM FOR SIMULTANEOUS ELECTRICITY AND FRESH WATER GENERATION

An integrated solar PV panel-membrane distillation system includes a solar photovoltaic panel having a front face for receiving solar energy and a back face, opposite to the front face and a membrane distillation device attached directly to the back face of the solar photovoltaic panel. The solar photovoltaic panel is configured to simultaneously generate electrical energy and transfer heat to the back membrane distillation device for generating fresh water from contaminated water. 1. An integrated solar PV panel-membrane distillation system comprising:a solar photovoltaic panel having a front face for receiving solar energy and a back face, opposite to the front face; anda membrane distillation device attached directly to the back face of the solar photovoltaic panel,wherein the solar photovoltaic panel is configured to simultaneously generate electrical energy and transfer heat to the back membrane distillation device for generating fresh water from contaminated water.2. The system of claim 1 , wherein the membrane distillation device is a single-stage membrane distillation device or a multi-stage membrane device claim 1 , which is composed by plural single-stage membrane distillation devices connected to each other.3. The system of claim 2 , wherein each single-stage membrane distillation device includes:a heat conduction layer configured to transfer heat;a water evaporation layer configured to evaporate the contaminated water to generate water vapor based on the heat received from the heat conduction layer;a hydrophobic layer configured to allow the water vapor to pass through, but not the contaminated water; anda condensation layer configured to condensate the water vapor into the fresh water.4. The system of claim 3 , wherein the heat conduction layer of a single-stage membrane distillation device of the plural single-stage membrane distillation devices is directly connected to the back face of the solar photovoltaic panel claim 3 , or directly uses the back ...

Method for making two-dimensional materials and composite membranes thereof having size-selective perforations

Two-dimensional materials having apertures in their basal planes are described, where at least a portion of the apertures are occluded with a selectively introduced occluding moiety. Occluding moieties that pass into apertures function to occlude apertures. Composite membranes are described having a porous substrate with a two-dimensional material disposed on the membrane and covering only a portion of the pores, wherein at least a portion of uncovered substrate pores are occluded. Pore occlusion can be achieved by introduction of an occluding particle optionally followed by chemical reaction, deformation or swelling of the particle to facilitate occlusion of pores. Two-dimensional materials covering substrate pores can be size-selected and optionally functionalized providing for selective permeability through composite membranes. Methods for occluding defects and apertures in two-dimensional materials and for selectively occluding pores in composite membranes are provided. Selectively occluded materials and membranes are useful in filtration and other applications.

TWO-DIMENSIONAL MEMBRANE STRUCTURES HAVING FLOW PASSAGES

A two-dimensional membrane layered structure may include a support substrate layer having a plurality of substrate passages configured to allow fluid to flow therethrough, a two-dimensional membrane layer disposed on an upper surface of the support substrate layer, and a plurality of flow passages disposed between the support substrate layer and the two-dimensional membrane layer. The two-dimensional membrane layer may have a plurality of pores configured to allow fluid to flow therethrough. The plurality of pores may comprise a first portion of pores that overlap with the plurality of substrate passages and a second portion of pores that do not overlap with the plurality of substrate passages. The plurality of flow passages may be configured to allow fluid to flow through the second portion of pores to the plurality of substrate passages. 1. A two-dimensional membrane layered structure comprising:a support substrate layer having a plurality of substrate passages configured to allow fluid to flow therethrough;a two-dimensional membrane layer disposed on an upper surface of the support substrate layer, the two-dimensional membrane layer having a plurality of pores configured to allow fluid to flow therethrough, the plurality of pores comprising a first portion of pores that overlap with the plurality of substrate passages and a second portion of pores that do not overlap with the plurality of substrate passages; anda plurality of flow passages disposed between the support substrate layer and the two-dimensional membrane layer, the plurality of flow passages being configured to allow fluid to flow through the second portion of pores to the plurality of substrate passages.2. The two-dimensional membrane layered structure of claim 1 , further comprising a plurality of interlayer supports disposed on an upper surface of the support substrate layer claim 1 , wherein the plurality of interlayer supports form the plurality of flow passages.3. The two-dimensional membrane ...

SYRINGE FILTER

The present invention provides a syringe for filtering a liquid comprising: a housing with a plunger slidable therein; an inlet for taking in liquid from a liquid source into the housing; an outlet for expelling liquid from the inside of the housing; a filter; and a rotatable valve member being rotatable between a first position and a second position; wherein rotation of the valve member to the first position permits liquid that is drawn through the inlet into the housing by pulling the plunger to bypass the filter, and rotation of the valve member to the second position forces liquid that is expelled from the inside of the housing by pushing the plunger to pass through the filter and out of the outlet. 1. A syringe for filtering a liquid comprising:a housing with a plunger slidable therein; an inlet for taking in liquid from a liquid source into the housing; an outlet for expelling liquid from the inside of the housing; a filter; and a rotatable valve member being rotatable between a first position and a second position;wherein rotation of the valve member to the first position permits liquid that is drawn through the inlet into the housing by pulling the plunger to bypass the filter, and rotation of the valve member to the second position forces liquid that is expelled from the inside of the housing by pushing the plunger to pass through the filter and out of the outlet.2. A syringe according to claim 1 , wherein the rotatable valve member is located between the filter and the inlet and outlet.3. A syringe according to claim 2 , wherein rotation of the valve member to the first position opens a first liquid path between the inlet and the inside of the housing which bypasses the filter; and rotation of the valve member to the second position closes the first liquid path claim 2 , thereby forcing liquid that is expelled from the housing to pass through a second liquid path between the inside of the housing and the outlet that passes through the filter.4. A syringe ...

PLASMA SEPARATOR APPARATUS AND ASSOCIATED METHODS

A plasma separator includes a vertical chamber with a membrane or membranes partially or fully covering the internal chamber walls and forming an inner cavity to accommodate whole blood. The plasma separator further includes a plasma collection space separated from the inner cavity with one or more membranes and a plasma removal port. 1. A plasma separator comprising:a chamber having one or more inner walls;at least one membrane vertically or essentially vertically oriented within the chamber, the at least one membrane forming an inner cavity within the chamber,a plasma collection space separated from the inner cavity by the at least one membrane; anda plasma removal port.2. The plasma separator of claim 1 , wherein the at least one membrane is hydrophilic or superhydrophobic.3. The plasma separator of claim 1 , wherein at least one of the one or more inner walls is hydrophilic or superhydrophobic.4. The chamber of in which at least one inner wall comprises one or more surface features.5. The chamber of claim 4 , in which at least one feature is a pillar.6. The chamber of claim 4 , in which at least one feature comprises a groove.7. The chamber of claim 4 , in which the feature supports the membrane.8. The chamber of in which the chamber has a circular cross-section claim 1 , rectangular cross-section claim 1 , ellipsoidal cross-section claim 1 , or triangular cross-section.9. The chamber of claim 1 , wherein the chamber has a cross-sectional dimension that varies within the chamber.10. A plasma separator comprising:a frame elongate along a central longitudinal axis, the frame having a top end and a bottom end spaced from the top end along the longitudinal axis, the frame defining a void elongate along the central longitudinal axis,a collection conduit, anda collection trench transverse to the central longitudinal axis and in fluid communication with the collection conduit,the frame further defining an outlet at a top end of the collection conduit; anda pair of ...

HYDROGEN GENERATION ASSEMBLIES AND HYDROGEN PURIFICATION DEVICES

Hydrogen generation assemblies, hydrogen purification devices, and their components are disclosed. In some embodiments, the devices may include a permeate frame with a membrane support structure having first and second membrane support plates that are free from perforations and that include a plurality of microgrooves configured to provide flow channels for at least part of the permeate stream. In some embodiments, the assemblies may include a return conduit fluidly connecting a buffer tank and a reformate conduit, a return valve assembly configured to manage flow in the return conduit, and a control assembly configured to operate a fuel processing assembly between run and standby modes based, at least in part, on detected pressure in the buffer tank and configured to direct the return valve assembly to allow product hydrogen stream to flow from the buffer tank to the reformate conduit when the fuel processing assembly is in the standby mode.

Hydrogen generation assemblies

Hydrogen generation assemblies and methods of generating hydrogen are disclosed. In some embodiments, the method may include receiving a feed stream in a fuel processing assembly of the hydrogen generation assembly; and generating a product hydrogen stream in the fuel processing assembly from the received feed stream. Generating a product hydrogen stream may, in some embodiments, include generating an output stream in a hydrogen generating region from the received feed stream, and generating the product hydrogen stream in a purification region from the output stream. The method may additionally include receiving the generated product hydrogen stream in a buffer tank of the hydrogen generation assembly; and detecting pressure in the buffer tank via a tank sensor assembly. The method may further include stopping generation of the product hydrogen stream in the fuel processing assembly when the detected pressure in the buffer tank is above a predetermined maximum pressure.

REVERSE OSMOSIS FILTERING MODULE AND REVERSE OSMOSIS FILTER COMPRISING SAME

A reverse osmosis filtering module includes: a purified water discharge pipe in which a purified water discharge path is formed, and which has a communication hole that is formed on an outer periphery thereof and communicates with the purified water discharge path; a reverse osmosis filtering part including a reverse osmosis filtering member in which a purified water flow space is formed, and which is wound around the purified water discharge pipe such that the purified water flow space communicates with the communication hole; a first flow channel formation cap provided at one side and having an inlet hole; and a second flow channel formation cap provided at the other side of the reverse osmosis filtering part and having an outlet hole. 1. A reverse osmosis filtering module , comprising:a purified water discharge pipe having a container shape in which a purified water discharge path is formed, and which has a communication hole that is formed on an outer periphery of the purified water discharge pipe and communicates with the purified water discharge path, one end of the purified water discharge path being opened and the other end of the purified water discharge path being closed;a reverse osmosis filtering part including a reverse osmosis filtering member in which a purified water flow space is formed, which is coupled to the purified water discharge pipe such that the purified water flow space communicates with the communication hole, and which is wound around the purified water discharge pipe multiple times to be formed of a cylindrical shape, the reverse osmosis filtering member having outer surfaces which face each other and between which a flow channel through which water flows is formed;a first flow channel formation cap coupled to one side of the reverse osmosis filtering part, and having an inlet hole connected to the flow channel such that raw water is introduced into the flow channel; anda second flow channel formation cap coupled to the other side of ...

Method for producing a filter intended to filter nanoparticles, obtained filter and associated method for the collection and quantitative analysis of nanoparticles

The present invention relates to a method for impregnating a filter having pores suitable for retaining particles within them that may be present in a flow of air suitable for passing through the filter, according to which the filter made up of a polymer membrane is impregnated with one or more organometallic salts by applying a treatment using supercritical CO 2 , the metal M of each salt being chosen from among the group of rare earths, yttrium, scandium, chromium, or a combination thereof. The invention also relates to the obtained filter and an associated method for the collection and quantitative analysis of nanoparticles.

CENTRAL TUBE FOR FILTER CARTRIDGE AND FILTERING DEVICE HAVING SAME

Provided are a central tube for a filter cartridge and a filter device having same. The central tube () comprises a first half tube (), a second half tube () and a membrane element (), wherein the first half tube () has a first mating surface, and the first mating surface is grooved to form a first flow channel (); the second half tube () has a second mating surface, the second mating surface is grooved to form a second flow channel (), and the first half tube () and the second half tube () are butt-jointed to form a hollow, straight tube shape; and the membrane element () is arranged between the first half tube () and the second half tube () and seals the first flow channel () and the second flow channel (), respectively. 1. A central tube for a filter cartridge , comprising:a first half-tube having a first fitting surface extending along an axial direction of the first half-tube, and the first fitting surface being slotted to provide a first flow passage extending along the axial direction, the first half-tube having a first close end and a second end having a first through hole communicated with the first flow passage, a side wall of the first half-tube having a first via hole communicated with the first flow passage;a second half-tube having a second fitting surface extending along an axial direction of the second half-tube, and the second fitting surface being slotted to provide a second flow passage extending along the axial direction, the second half-tube having a first closed end and a second end having a second through hole communicated with the second flow passage, a side wall of second half-tube having a second via hole communicated with the second flow passage, the first half-tube and the second half-tube being butted, the first fitting surface and the second fitting surface being opposite to each other, the first half-tube and the second half-tube being fitted to provide a hollow straight tube; anda membrane element disposed between the first half-tube ...

RESERVOIR-BASED MANAGEMENT OF VOLUMETRIC FLOW RATE IN FLUIDIC SYSTEMS

Reservoir-based management of volumetric flow rates in fluidic systems is generally described. Inventive systems and methods for liquid-liquid separations and/or liquid-gas separations are also described. 1. A fluidic system , comprising:a first fluidic separator;a second fluidic separator;a first fluidic pathway fluidically connected to the first fluidic separator and the second fluidic separator; anda second fluidic pathway fluidically connected to the first fluidic separator and the second fluidic separator, the second fluidic pathway comprising a first segment, a second segment, a pump, and a reservoir;wherein the reservoir is between the first segment and the second segment;wherein the pump is between the second segment and an inlet of the first fluidic separator; andwherein at least a portion of a wall of the reservoir is flexible.2. The fluidic system of claim 1 , wherein the maximum cross-sectional dimension of the reservoir is at least 3 times larger than the average of the maximum cross-sectional dimensions of the portions of the second fluidic pathway immediately upstream of the reservoir and immediately downstream of the reservoir.3. The fluidic system of claim 1 , wherein the reservoir is configured such that claim 1 , during use claim 1 , the volumetric flow rate of fluid within the first segment of the second fluidic pathway is decoupled from the volumetric flow rate of fluid within the second segment of the second fluidic pathway.4. The fluidic system of claim 1 , wherein the reservoir is an enclosed reservoir.56-. (canceled)7. A fluidic system claim 1 , comprising:a first fluidic separator;a second fluidic separator;a first fluidic pathway fluidically connected to the first fluidic separator and the second fluidic separator; anda second fluidic pathway fluidically connected to the first fluidic separator and the second fluidic separator, the second fluidic pathway comprising a first segment, a second segment, a pump, and an enclosed reservoir; ...

Sample preparation device

A sample preparation device (1) comprising a first chamber (2) containing a membrane support (30) on which a membrane (9) is placed or can be placed, an inlet (20) to the first chamber (2) and an outlet (21) from the first chamber (2), at least one second chamber (3) provided with or adapted to be provided with an anaerobic generation means (23) and/or an anaerobic detection indicator, wherein the at least one second chamber (3) is connected to the first chamber (2) by a communication path (8), wherein the communication path (8) is liquid-tightly closed by a tap device (4) in a first position (A) of the tap device (4) and is adapted to be opened to allow fluid communication between the first chamber (2) and the at least one second chamber (3) in that the tap device (4) is moved to a second position (B) of the tap device (4).

BIOMARKER DETECTION DEVICE

The disclosure is directed to a device that includes an upper container configured to receive a fluid sample collected from a mammal into a first opening, the first opening opposite a second opening and a membrane covering at least a portion of the second opening, the membrane configured to allow transmission of a portion of the fluid sample through the membrane.

Capillary Pressure Re-Set Mechanism and Applications

Many hand-held diagnostics are limited in their functionality due to the challenging physics associated with small dimensional systems. An example of this is capillary forces in hydrophilic systems, such as the tight retention of liquid passing through a small pore filtration membrane, or capillary force driven microfluidics where, to keep liquid flowing the dimensions of the system become so small that the flow rates are too low to be useful, or the manufacturing of such devices becomes uneconomical. This disclosure details methods to ‘reset’ the capillary force condition to avoid the requirement of transient pressure spikes associated with the breakthrough pressure of small pore membranes, and avoid the necessity of extremely small microfluidic channels, which can be useful in applications such as filtration of whole blood to plasma using only suction pressure or passive capillary pressure. 1. A device useful for filtering a liquid sample , said device comprised of: a membrane filter with the desired filtration properties; a soluble matrix in physical contact with at least a portion of the downstream surface of said membrane filter; said soluble matrix possessing a capillary drawing force sufficient to draw filtrate through said membrane filter and into itself , after which a portion of said soluble matrix dissolves in said filtrate which dissolution releases said filtrate from said soluble matrix; a base structure used to support said soluble matrix so that it is in physical contact with said membrane filter.2. The device of claim 1 , wherein said base structure consists of a membrane with lower capillarity than that of said membrane filter and which said filtrate released from said soluble matrix passes into said base structure membrane.3. The device of claim 1 , wherein said base structure consists of a solid claim 1 , material useful for supporting said soluble matrix against said membrane filter; wherein said base structure serves as a surface for storing or ...

Filter

A filter for a hemodialysis apparatus is provided, which includes: a first cover member, a second cover member coupled to the first cover member, and a membrane disposed in a chamber of the first cover member. The membrane has a first membrane layer and two second membrane layers respectively bonded to two opposite sides of the first membrane layer. A plurality of first ridges and second ridges are formed on a side surface of the second cover member, spaced apart from one another and having different widths so as to increase the friction force. The non-directional three-layer structure of the membrane has a high water pressure resistance, greatly reduces the chance of fluid leakage, and avoids erroneous disposition.

PORTABLE FILTRATION UNIT

The present invention relates to portable filtration units including filter components mated with retentate and permeate flow channels wherein particle containing solutions are introduced into the portable filtration units and contacted with the filter components for filtration thereby producing a retentate outflow and a permeate outflow for capture of desired end product. 2. The method of claim 1 , wherein the portable filtration unit further comprises a retentate gasket and a permeate gasket positioned adjacent to the second retentate surface and the second permeate surface claim 1 , respectively claim 1 , wherein the retentate gasket and permeate gasket include elongated channels along the longitudinal axis of the endplates claim 1 , wherein the elongated channels are in fluid communication with each other and the opening in the retentate gasket is longitudinally extended beyond the elongated opening in the permeate gasket.3. The method of claim 1 , wherein the filter membrane sheet has a porosity rating that allows particles smaller than the pores to pass through and larger particles will remain in the retentate stream.4. The method of claim 1 , wherein the permeate sheet provides flow channels for flow of the permeate within the permeate flow channel.5. The method of claim 1 , wherein the retentate flow channel is configured such that fluid flows essentially without deflection from the retentate inlet port to the retentate outlet port.6. The method of claim 1 , wherein the filter membrane sheet is fabricated from polypropylene claim 1 , polyethylene claim 1 , polysulfone claim 1 , polyethersulfone claim 1 , polyetherimide claim 1 , polyimide claim 1 , polycarbonate claim 1 , polyvinylchloride claim 1 , polyester claim 1 , nylon claim 1 , silicone claim 1 , urethane claim 1 , cellulose nitrate claim 1 , cellulose acetate claim 1 , regenerated cellulose claim 1 , polyether amide or any combination thereof7. The method of claim 1 , wherein the retentate gasket is ...

INSTRUMENTS, MODULES, AND METHODS FOR IMPROVED DETECTION OF EDITED SEQUENCES IN LIVE CELLS

The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited. 1. A singulation assembly for a solid wall isolation , incubation and normalization (SWIIN) module comprising: an upper surface and a lower surface and a first and second end,', 'an upper portion of a serpentine channel defined by raised areas on the lower surface of the retentate member, wherein the upper portion of the serpentine channel traverses the lower surface of the retentate member for about 50% to about 90% of a length and width of the lower surface of the retentate member; and', 'at least one retentate port fluidically connected to the serpentine channel; and, 'a retentate member comprising;'} an upper surface and a lower surface and a first and second end,', 'a lower portion of the serpentine channel defined by raised areas on the upper surface of the permeate member, wherein the lower portion of the serpentine channel traverses the upper surface of the permeate member for about 50% to about 90% of a length and width of the upper surface of the permeate member, and wherein the lower portion of the serpentine channel is configured to mate with the upper portion of the serpentine channel to form the serpentine channel; and', 'at least one permeate port fluidically connected to the serpentine channel; and, 'a permeate member disposed under the retentate member comprisinga first gasket disposed under and adjacent to the retentate member and above and adjacent to the permeate member.2. A SWIIN module comprising the singulation assembly of further comprising:first and second reservoirs at the first end of the permeate member, wherein the first reservoir is fluidically connected to the at ...

MEMBRANE EMULSIFICATION DEVICE FOR MICROSPHERE CREATION

The present disclosure is directed to cross-flow membrane emulsification devices. The devices disclosed herein can have a continuous phase plate, a dispersed phase plate, an outlet, and a chamber. The chamber is located between the continuous phase plate and the dispersed phase plate and is bisected by a membrane with a plurality of pores. The chamber can include at least one channel on a first side of the membrane formed from at least one groove in the continuous phase plate and the membrane. In addition, the chamber can also include a cavity on a second side of the membrane formed in the dispersed phase plate. 1. A device , comprising:a continuous phase plate comprising a continuous phase inlet;a dispersed phase plate comprising a dispersed phase inlet;an outlet; anda chamber located between the continuous phase plate and the dispersed phase plate that is bisected by a membrane comprising a plurality of pores, wherein the chamber comprises:at least one channel on a first side of the membrane formed from at least one groove in the continuous phase plate and the membrane, wherein the at least one channel is fluidly connected between the continuous phase inlet and the outlet; anda cavity on a second side of the membrane formed in the dispersed phase plate that is fluidly connected between the dispersed phase inlet and the plurality of pores in the membrane.2. The device of claim 1 , wherein the at least one channel extends in a direction transverse to a flow of a dispersed phase through the plurality of pores.3. The device of any of - claim 1 , wherein the continuous phase plate comprises the outlet.4. The device of any of - claim 1 , wherein the dispersed phase plate comprises a dispersed phase outlet.5. The device of any of - claim 1 , wherein the continuous phase plate comprises at least two grooves.6. The device of claim 5 , wherein the chamber comprises at least two channels on the first side of the membrane formed from the at least two grooves in the continuous ...

Pulse-modulated periodic backflush for clearance of fouling layers in dead-end filtration systems

Embodiments of the present disclosure relate generally to dead-end filtration systems and, more particularly, to pulse-modulated periodic backflush systems and methods for clearing fouling layers in dead-end filtration systems. In some embodiments, a controller may control the flow of fluid in the system from cycling from a forward flow to a reverse flow. In some embodiments, the controller may cycle from forward to reverse flow based on a volumetric flow ratio. Embodiments of the present disclosure describe optimal volumetric flow ratios for optimizing the break of cake in a dead-end filtration system. Embodiments of the present disclosure describe optimal volumetric flow ratios for optimizing recovery percentages of targeted particles.

CONNECTION DEVICE FOR A SUCTION APPARATUS OF A VACUUM DIAPHRAGM FILTER

A connection mechanism for a suction device for vacuum membrane filtration applications, includes a support for receiving a membrane filter or a filtration base, a cavity formed below the membrane filter or the filtration base, a suction duct which opens centrally into the cavity, and a ventilation duct which opens laterally into the cavity. The connection mechanism further includes a closing element which can be moved into several switching positions and which can block or unblock both the suction duct and the ventilation duct depending on the switching positions. 1. A connection means for a suction device for vacuum membrane filtration applications , comprisinga support for receiving a membrane filter or a filtration base,a cavity formed below the membrane filter or the filtration base,a suction duct which opens centrally into the cavity, anda ventilation duct which opens laterally into the cavity,characterized by a closing element which can be moved into several switching positions and which can block or unblock both the suction duct and the ventilation duct depending on the switching positions.2. The connection means according to claim 1 , characterized in that the ventilation duct opens into the cavity via a collecting part of the cavity.3. The connection means according to claim 1 , characterized in that the ventilation duct is separated from the suction duct in each switching position.4. The connection means according to claim 1 , characterized in that the closing element has both at least one suction duct part for completing the suction duct in at least one switching position and at least one ventilation duct part for completing the ventilation duct in at least one switching position.5. The connection means according to claim 1 , characterized in that in a first switching position claim 1 , the suction duct is unblocked and the ventilation duct is blocked.6. The connection means according to claim 5 , characterized in that in a second switching position ...

RESIN BARRIER DEVICE, GASKET AND METHOD FOR INFUSING A PREFORM

A resin barrier device for connection in a vacuum line, for use in resin infusion during composite manufacture, includes a housing having an inlet port for connection to a resin source and an outlet port for connection to a vacuum source. A flow path extends between the inlet and outlet ports. A gas-permeable membrane is disposed across the flow path to prevent resin from flowing to the vacuum pump. A gasket supports the membrane and is adapted to prevent resin leakage. A method of infusing a preform with a resin also is provided. 1. A resin barrier device for use in resin infusion of a composite preform , the resin barrier device comprising:a housing having an inlet port for connection to a resin source;an outlet port for connection to a vacuum source;a flow path extending between the inlet and outlet ports, wherein a portion of the flow path has an increased flow area that is larger than the flow area of either the inlet port or the outlet port; anda gas-permeable membrane across the increased flow area portion of the flow path.2. The resin barrier device according to claim 1 , wherein the flow pathway extends along an axis through the housing claim 1 , and wherein the housing is symmetrically disposed around the axis.3. The resin barrier device according to claim 1 , wherein the housing comprises separable first and second portions claim 1 , to provide access to the membrane.4. The resin barrier device according to claim 3 , wherein the first portion comprises the inlet port and the second portion comprises the outlet port.5. The resin barrier device according to claim 3 , wherein each of the first and second portions comprise a flange claim 3 , by which they are secured to one another.6. The resin barrier device according to claim 3 , wherein the first and second portions are secured together using at least one of a tri-clover fitting or one or more bolts.7. The resin barrier device according to claim 3 , further comprising a sealing arrangement between the ...

BARRIER VENT ASSEMBLY

The technology disclosed herein relates to a vent assembly having a vent housing that defines a first airflow pathway, a second airflow pathway, and a third airflow pathway. The first airflow pathway is configured for fluid communication with an interior of an enclosure. The second airflow pathway is configured for fluid communication with the external environment, and the third airflow pathway extends between the first airflow pathway and the second airflow pathway. A membrane is coupled to the vent housing such that the second airflow pathway and the third airflow pathway are in communication through the membrane. Coalescing filter media is disposed within the vent housing such that the third airflow pathway and the first airflow pathway are in communication through the coalescing filter media. The vent assembly defines a spacing region between the coalescing media and the membrane. 120-. (canceled)21. A vent assembly comprising:a vent housing defining a mounting structure and an airflow pathway extending from the mounting structure to the environment external to the vent housing; anda membrane coupled to the vent housing and disposed across the airflow pathway, the vent assembly defining a coalescing region within the airflow pathway between the mounting structure and the membrane; andthe vent assembly defining a spacing region between the coalescing region and the membrane, wherein the vent assembly defines a draining pathway from the coalescing region through the portion of the airflow pathway in the mounting structure.22. The vent assembly of claim 21 , wherein the coalescing region comprises coalescing filter media.23. The vent assembly of claim 21 , wherein the coalescing filter media comprises a plurality of layers synthetic filter media.2425-. (canceled)2624. The vent assembly of claim - 23 , wherein each of the layers of synthetic filter media has a central axis 23 , and a plurality of the central axes are not collinear.27. The vent assembly of claim 23 , ...

SURFACE TENSION DRIVEN FILTRATION

Disclosed is a device for extracting a filtrate from a liquid sample that includes one or more filtration membranes and, in physical contact with a portion of the downstream surface(s) of the filtration membrane(s), a soluble matrix possessing a capillary drawing force sufficient to draw filtrate through the at least one filtration membrane and into the soluble matrix, causing the soluble matrix to at least partially dissolve or disintegrate in the filtrate, whereby the filtrate is released. Various configurations, including device configurations having two filtration membranes with a soluble matrix in between or having a tubular filtration membrane at least partially surrounding or surrounded by a soluble matrix are described. 1. A device for extracting a filtrate from a liquid sample , the device comprising:at least one filtration membrane; anda soluble matrix in physical contact with at least a portion of a downstream surface of the at least one filtration membrane, the soluble matrix possessing a capillary drawing force sufficient to draw filtrate through the at least one filtration membrane and into the soluble matrix, causing the soluble matrix to at least partially dissolve or disintegrate in the filtrate, whereby the filtrate is released.2. The device of claim 1 , further comprising a base material claim 1 , support membrane claim 1 , or housing to hold the soluble matrix in contact with the at least one filtration membrane.3. The device of claim 1 , wherein the at least one filtration membrane is a plasma separation membrane.4. The device of claim 3 , wherein the plasma separation membrane is treated to improve filtering performance for a specified biomarker.5. The device of claim 4 , wherein the specified biomarker is an antibody claim 4 , antigen or nucleic acid component of or for a coronavirus.6. The device of claim 1 , wherein the at least one filtration membrane comprises two filtration membranes arranged substantially in parallel and facing each ...

Filtration unit and method for the microbiological examination of liquid samples

Filtrationseinheit mit einem auf einer Filterunterstützung eines Unterteiles anordenbaren Membranfilter und einem auf das Unterteil aufsetzbaren Aufsatz, wobei der Membranfilter einen Verstärkungsrand aufweist und wobei der Membranfilter zur Entnahme mit einem Klemmteil eines Deckels einer Nährmedieneinheit verklemmbar und in die Nährmedieneinheit einbringbar ist. Verfahren zur mikrobiologischen Untersuchung flüssiger Proben nach vorangegangener Filtration, bei dem ein Membranfilter nach Entfernen eines Aufsatzes zum Aufgießen der flüssigen Probe auf einer Filterunterstützung abgehoben und auf einer Oberfläche eines in einem Unterteil einer Nährmedieneinheit angeordneten Nährbodens abgelegt und das Unterteil von einem Deckel abgedeckt wird, wobei der Deckel auf die auf der Filterunterstützung liegende Membran so aufgesetzt wird, dass ein in dem Deckel angeordnetes Klemmteil mit einem Verstärkungsrand der Membran sich verklemmt und wobei der Deckel mit der Membran von der Filterunterstützung abgehoben und auf das schalenförmige Unterteil so aufgesetzt wird, dass die dem Deckel abgewandte Unterseite der Membran auf der dem Deckel zugewandten Oberseite des Nährbodens aufliegt. Filtration unit with a can be arranged on a filter support of a lower part membrane filter and an attachable to the lower part essay, wherein the membrane filter has a reinforcing edge and wherein the membrane filter for removal with a clamping part of a lid of a Nährmedieneinheit clamped and can be introduced into the Nährmedieneinheit. A method for microbiological examination of liquid samples after previous filtration, in which a membrane filter is lifted after removal of an attachment for pouring the liquid sample on a filter support and placed on a surface of a placed in a lower part of a Nährmedieneinheit nutrient medium and the lower part is covered by a lid, wherein the lid is placed on the membrane supported on the filter support so that a clamp disposed in the lid clamped with a ...

Hydrogen permeable membrane and hydrogen permeating assembly

Verfahren zur Sauerstoffanreicherung in Gasen, dafür geeignete Anlagen sowie deren Verwendung

Beschrieben wird ein Verfahren zur Anreicherung des Gehalts von Sauerstoff in Sauerstoff und Stickstoff enthaltenden Gasen in einer Trennvorrichtung, die einen Innenraum aufweist, der durch eine Sauerstoff leitende keramische Membran in eine Substratkammer und in eine Permeatkammer geteilt wird. Das Verfahren beinhaltet das Einleiten von Sauerstoff und Stickstoff enthaltendem Spülgas in die Permeatkammer sowie die Einstellung eines solchen Druckes in der Substratkammer, dass der Sauerstoff-Partialdruck in Substrat- und Spülkammer den Transport von Sauerstoff durch die keramische Membran bewirkt. DOLLAR A Das Verfahren zeichnet sich durch eine hohe Betriebssicherheit aus.

Process for reducing carbon production in solid electrolyte ionic conductor systems

A process for inhibiting the formation of carbon and/or coke from a carbon-containing reactive gas stream on the permeate side of an oxygen ion transport membrane, or for increasing the oxygen partial pressure thereon, by separating a feed gas stream to form an oxygen-depleted gas stream on the retentate side and a gas stream containing oxygen reaction products on the permeate side. The permeate side is purged with the carbon-containing reactive gas stream, and at least a portion of the exhaust gas stream formed from the reaction of the reactive gas stream with the separated oxygen is recirculated to purge the permeate side.

METHOD FOR PRODUCING FILTER FOR FILTRATION OF NANOPARTICLES, FILTER OBTAINED AND METHOD FOR COLLECTING AND QUANTITATIVE ANALYSIS OF NANOPARTICLES THEREOF