КОНВЕРСИЯ ТЯЖЕЛЫХ ИСКОПАЕМЫХ УГЛЕВОДОРОДОВ И МОДЕРНИЗАЦИЯ С ИСПОЛЬЗОВАНИЕМ РАДИОЧАСТОТНОЙ ИЛИ МИКРОВОЛНОВОЙ ЭНЕРГИИ

FIELD: oil and gas industry.SUBSTANCE: invention relates to a method for continuous instantaneous conversion of heavy fossil hydrocarbons (HFH) mixture, comprising one or more of bitumen, coal of any kind, oil sands, oil shales, oil resins, asphaltenes and predasphaltenes, as well as any other kerogen-containing materials. The method comprises: flowing a continuously fed stock, containing said HFH mixture and process gas through a reaction zone having more than 0.9 atmospheres pressure; dspersing said HFH mixture and the HFH distillation catalyst in the liquid in the process gas, and contacting said HFH mixture and catalyst at least in the reaction zone; concentrating microwave or radio frequency (RF) energy in the reaction zone using a microwave source or RF energy; and the generation of dielectric discharges in the reaction zone. In this case, said HFH mixture and the catalyst have stay period in the reaction zone less than 30 seconds. Also, the invention relates to two variants of continuous conversion system for HFH mixture.EFFECT: invention allows to reduce the environmental impact of heavy fossil hydrocarbons, and also allows conversion at lower temperature and pressure.30 cl, 16 tbl, 5 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 636 151 C2 (51) МПК C10G 15/08 (2006.01) C10G 1/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2014138093, 20.11.2012 (24) Дата начала отсчета срока действия патента: 20.11.2012 Дата регистрации: Приоритет(ы): (30) Конвенционный приоритет: 21.02.2012 US 13/401,216 (45) Опубликовано: 21.11.2017 Бюл. № 33 (56) Список документов, цитированных в отчете о поиске: EP 0601798 A1, 15.06.1994. US (85) Дата начала рассмотрения заявки PCT на национальной фазе: 22.09.2014 2004074759 A1, 22.04.2004. WO 0238523 A1, 16.05.2002. US 4279722 A, 21.07.1981. US 6171479 B1, 09.01.2001. US 6184427 B1, 06.02.2001. US 2007102279 A1, 10.05.2007. RU 2342997 C2, 10.01.2009. (86) Заявка PCT ...

A reactor device for reaction fluid

Heavy fossil hydrocarbon conversion and upgrading using radiofrequency or mirowave energy

Apparatus and methods for fluid processing and flow control

Fluid processing apparatus has a prefabricated branched network of flexible tubing (2), for conducting process fluid between process elements of the apparatus, and control valves (8). A tubing support (1) has opposable front and rear plates (6, 7) which define a pattern of support channels (60) between them in which the flexible tubing network lies, so that the support channels limit or prevent expansion of the flexible tubes. Standard non-reinforced tubing can then be used for high-pressure work. The support body plates (6, 7) can be separated to open the channels for insertion or removal of the flexible tubing. The front plate may be transparent. The control valves (8) operate by simply pressing on the tubing in the support channels to block flow, without invasion of the flow path. The tubing sets can be easily replaced, cleaned or sterilised. The invention is useful in a range of controlled-flow processes e.g. chromatography and filtration.

METHOD FOR THE CONTINUOUS PRODUCTION OF BIOMETHANOL DIESEL

HEAVY FOSSIL HYDROCARBON CONVERSION AND UPGRADING USING RADIO-FREQUENCY OR MICROWAVE ENERGY

Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.

CATALYST SUPPORT STRUCTURE, CATALYST INCLUDING THE STRUCTURE, REACTOR INCLUDING A CATALYST, AND METHODS OF FORMING SAME

Structures, catalysts, and reactors suitable for use for a variety of applications, including gas-to-liquid and coal-to-liquid processes and methods of forming the structures, catalysts, and reactors are disclosed. The catalyst material can be deposited onto an inner wall of a microtubular reactor and/or onto porous tungsten support structures using atomic layer deposition techniques.

SYSTEM, METHODS AND DEVICES FOR CASCADE REACTORS FISCHER - TROPSCH

MICROFLUIDIC CASSETTE FOR SYNTHESIZING A RADIO-TRACER SYNTHESIS FOR A RADIO-TRACER WITH SUCH CASSETTE

DEVICE USEFUL FOR HYDROGENATION REACTIONS(I)

본 발명은, 수송된 물질을 하나 이상의 다공성 부재를 포함하는 장치를 통해 처리하는 장치에 관한 것이며, 이때 상기 다공성 부재는, 상기 다공성 부재를 통한 물질의 교차-흐름을 허용하는 특정 고체 금속 구조물로 이루어지고, 상기 다공성 부재는, 팔라듐(Pd)으로 함침된 비-산성 금속 산화물로 코팅된다. The present invention is directed to an apparatus for treating a transported material through a device comprising at least one porous member, wherein the porous member consists of a specific solid metal structure that allows cross-flow of material through the porous member. The porous member is coated with a non-acidic metal oxide impregnated with palladium (Pd).

METHOD FOR MANUFACTURING A HETEROGENEOUS CATALYST BASED ON SPATIAL SPECIFICITY CAPABLE OF INCREASING THE CATALYTIC CHARACTERISTIC OF A HETEROGENEOUS CATALYST

PURPOSE: A method for manufacturing a heterogeneous catalyst based on spatial specificity is provided to prevent the entanglement phenomenon of particles by forming two different materials separately in the center part and the peripheral part of one nano-particle. CONSTITUTION: A method for manufacturing a heterogeneous catalyst includes the following: a micelle-formed substrate is immersed in a solution containing a metal precursor to deposit one metal selected from iron, platinum, cobalt, palladium, and ruthenium on the center part of the micelle formed on the substrate; the substrate, an oxide precursor, and water are introduced into a sealed container; a thermal treating process is implemented under a temperature at which the oxide precursor and the water are vaporized; the oxide is deposited on the peripheral part of the micelle; and the metal on the center part of the micelle is reduced to eliminate micelle. The metal precursor is one selected from an iron precursor, a platinum precursor, a cobalt precursor, a palladium precursor, and a ruthenium precursor. The oxide precursor is one selected from a silica precursor and a titanium precursor.

High pressure homogenizer and manufacturing method for Graphene using the same

본 발명은 고압 균질화 장치 및 이를 이용한 그래핀의 제조방법에 관한 것으로, 본 발명의 일 측면에 따르면, 균질화를 위한 대상물이 통과하는 마이크로 채널을 포함하는 채널 모듈을 포함하며, 채널 모듈은 상기 마이크로 채널을 복수 개의 공간으로 구획하도록 배치된 하나 이상의 배플을 포함하고, 배플은 상기 마이크로 채널을 폭 방향 또는 높이 방향에 따라 2개의 공간으로 구획하도록 마련된 고압 균질화 장치가 제공된다.

FLOW REACTOR FLUID CONNECTION APPARATUS AND METHOD

A flow reactor [] includes a fluidic module [] having an external surface [], an internal process fluid path [], and an input port [I] and an output port [O] connected to the process fluid path []. An upstream coupler [] is connected to the input port [I], and a downstream coupler [] is connected to the output port [O]. The upstream coupler [] has a gasket [] in a gasket groove [] pressed against the fluidic module [] and a hollow circular cylindrical post [] protruding from the upstream coupler [] and extending into the input port [I]. The downstream coupler [] has a gasket [] in a gasket groove [] pressed against the fluidic module [] and no hollow circular cylindrical post extending into the output port [O]. 1. A flow reactor comprising:a fluidic module having an external surface, an internal process fluid path, and an input port and an output port each in the form of an opening in the external surface, the process fluid path extending from the input port to the output port;an upstream coupler connected to the input port, the upstream coupler comprising an upstream coupler body having an upstream gasket, the upstream gasket pressed against the external surface of the fluidic module by an upstream coupler face of the upstream coupler body, the upstream gasket surrounding the input port; anda downstream coupler connected to the output port, the downstream coupler comprising a downstream coupler body and a downstream gasket, the downstream gasket pressed against the external surface of the fluidic module by a downstream coupler face of the downstream coupler body, the downstream gasket surrounding the output port;wherein the upstream coupler body comprises an upstream gasket groove in the upstream coupler face holding the upstream gasket and a hollow circular cylindrical post protruding from the upstream coupler face and extending into the input port, and wherein the downstream coupler body comprises a downstream gasket groove in the downstream coupler face holding ...

DETERMINATION OF AT LEAST ONE PARAMETER OF A PHYSICAL AND/OR CHEMICAL TRANSFORMATION

Physico-chemical systems subject to transformation are flowed in a flow member, while maintaining the external periphery of the wall of such flow member at one and the same temperature, with the exception of a display zone, at least between two remote points along said member; at least one spatial distribution of the temperature of the physico-chemical system along this display zone is displayed, in particular comprising an infrared camera, and the or each parameter is determined therefrom utilizing the or each spatial temperature distribution.

НЕПРЕРЫВНЫЙ СПОСОБ ПОЛУЧЕНИЯ ВЫСОКО РАЗВЕТВЛЕННЫХ ПОЛИМЕРОВ НА ОСНОВЕ ЭТИЛЕННЕНАСЫЩЕННОЙ МОНО-ИЛИ ДИКАРБОНОВОЙ КИСЛОТЫ, СОДЕРЖАЩЕЙ ОТ 3 ДО 8 АТОМОВ УГЛЕРОДА, ИЛИ ЕЕ АНГИДРИДОВ И ЕЕ СОЛЕЙ

PROCEDURE FOR THE CONTINUOUS PRODUCTION OF BIO METHANOL DIESEL

Surface functionalization

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

Heavy fossil hydrocarbon conversion and upgrading using radio-frequency or microwave energy

Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.

APPARATUS, SYSTEMS, AND METHODS FOR CONTINUOUS MANUFACTURING OF NANOMATERIALS AND HIGH PURITY CHEMICALS

A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided.

FLOW-THROUGH REACTORS FOR THE CONTINUOUS QUENCHING OF PEROXIDE MIXTURES AND METHODS COMPRISING THE SAME

This disclosure relates to a highly efficient and safe reactor for the continuous quenching of peroxide mixtures generated during the reaction of unsaturated compounds with ozone, which minimizes the amount of highly reactive peroxides accumulated in the reactor at any given time. The reactor may be modified to allow for expansion to accommodate the quenching parameters of a wide variety of ozonolysis reactions and flow rates. The reactor may be constructed from highly pressure rated stainless steel for maximum durability, safety, and economic practicality while increasing the safety of peroxide quenching, thus allowing tighter process control and improved product yields. This disclosure also related to methods for quenching ozonides.

PROCESS AND INSTALLATION OF DETERMINATION Of AT LEAST a PARAMETER Of a PHYSICAL AND/OR CHEMICAL TRANSFORMATION

SYSTEM OF WATER SEPARATION

Système de séparation d'eau (100), il comprend une unité de mélange 3 dans laquelle les ingrédients sont introduits et mélangés, une unité de traitement réactionnel chimique 4 qui est disposé sous l'unité de mélange 3 et dans laquelle les ingrédients mélangés subissent une réaction chimique, une unité de séparation d'eau 6 connectée sous l'unité de traitement réactionnel chimique 4 pour séparer l'eau produite dans l'unité de traitement réactionnel chimique 4, et une unité de contrôle 12 pour contrôler le temps de réaction chimique dans l'unité de traitement réactionnel chimique 4. L'unité de contrôle 12 raccourcit le temps de réaction chimique dans l'unité de traitement réactionnel chimique 4 quand la solution déchargée de l'unité de traitement réactionnel chimique 4 contient une grande quantité de produit, et prolonge le temps de réaction chimique dans l'unité 4 quand la solution déchargée de l'unité 4 contient une petite quantité de produit.

КОНВЕРСИЯ ТЯЖЕЛЫХ ИСКОПАЕМЫХ УГЛЕВОДОРОДОВ И МОДЕРНИЗАЦИЯ С ИСПОЛЬЗОВАНИЕМ РАДИОЧАСТОТНОЙ ИЛИ МИКРОВОЛНОВОЙ ЭНЕРГИИ

... 1. Способ непрерывной мгновенной конверсии тяжелых ископаемых углеводородов (ТИУ), содержащий:протекание непрерывно подаваемого сырья, содержащего ТИУ и технологический газ, через зону реакции, имеющую давление более чем 0,9 атм;контактирование ТИУ и катализатора перегонки ТИУ в жидкости в по меньшей мере зоне реакции;концентрирование микроволновой или радиочастотной (РЧ) энергии в зоне реакции с использованием источника микроволновой или РЧ энергии; игенерирование диэлектрических разрядов в зоне реакции;при этом ТИУ и катализатор имеют время пребывания в зоне реакции менее чем 30 с.2. Способ по п. 1, в котором технологический газ содержит водородсодержащий газ.3. Способ по п. 1, в котором катализатор содержит железо.4. Способ по п. 1, в котором катализатор содержит кокс.5. Способ по п. 1, в котором катализатор содержит активатор диэлектрического разряда.6. Способ по п. 1, в котором ТИУ и катализатор смешивают.7. Способ по п. 1, дополнительно содержащий генерирование плазмы в зоне реакции ...

Непрерывный способ синтеза графт-полимеров на основе простых полиэфиров

1. Непрерывный способ получения амфифильных графт-полимеров, в котором компонент (B) сложного винилового эфира, состоящий из винилацетата и/или винилпропионата (B1) и при необходимости дополнительно этиленненасыщенного мономера (B2), полимеризуется в присутствии полиалкиленоксида (A), инициатора (C), образующего свободные радикалы, и при необходимости добавки (D) при средней температуре полимеризации, при которой инициатор (C) имеет период полуразложения от 1 до 500 мин, по меньшей мере в одном трубчатом сегменте реактора с подающим участком и выпускным участком, причем через указанный сегмент протекает реакционная смесь, содержащая по меньшей мере часть компонента от (A) до (C) и при необходимости (D), при этом по меньшей мере два трубчатых сегмента реактора соединены последовательно, первый трубчатый сегмент реактора имеет первый подающий участок и первый выпускной участок, первый трубчатый сегмент реактора соединяется со вторым трубчатым сегментом реактора через первый выпускной участок, который соответствует второму подающему участку второго трубчатого сегмента, и в связи с этим по меньшей мере один возвратный поток удаляется из выпускного участка по меньшей мере одного трубчатого сегмента реактора и возвращается в подающий участок одного из трубчатых сегментов реактора.2. Непрерывный способ по п. 1, в котором полимеризация происходит по меньшей мере в двух трубчатых сегментах реактора, соединенных последовательно.3. Непрерывный способ по п. 1 или 2, в котором отношение возвратного потока к подаваемому потоку находится между 1 и 1000.4. Непрерывный способ п. 2, в котором- 90-100% общего количества компонента (A) вводят в первый подающий участок,- 0-60% общего количества комп

Systems and methods for thermally actuated flow control

Various implementations provide an inherently safer design feature for microchannel reactors that provides temperature control at the individual channel level. This approach relies on bimetallic strips embedded within the combustion channel, forming a thermally-actuated "valve". Bimetallic strips convert a temperature change into a mechanical displacement. Heating the strip increases its deflection and thereby restricts flow in the combustion channels, which consequently reduces the rate of heat generation. The thermally-actuated valve is not limited to use in microchannel reactors and may be used in other structures for which thermally actuated flow control is desired, according to some implementations.

Microfluidic cassette for synthesising a radiotracer and method for synthesising a radio-tracer with such a cassette

The present application concerns a microfluidic cassette for synthesising a radiotracer comprising a microfluidic circuit in a support card that comprises at least one intake for supply by a vial (Pf), at least one isotope port (IP), at least one reaction chamber (R1, R2, R3, R4), at least one mixing chamber (M1, M2, M3, M4), at least one formulation chamber (FC), and at least one connection for a syringe (SP), linked together by capillaries. The invention also relates to a method for synthesising a radiotracer in such a cassette.

APPARATUS AND METHODS FOR FLUID PROCESSING AND FLOW CONTROL

Fluid processing apparatus has a prefabricated branched network of flexible tubing (2), for conducting process fluid between process elements of the apparatus, and control valves (8). A tubing support (1) has opposable front and rear plates (6, 7) which define a pattern of support channels (60) between them in which the flexible tubing network lies, so that the support channels limit or prevent expansion of the flexible tubes. Standard non-reinforced tubing can then be used for high-pressure work. The support body plates (6, 7) can be separated to open the channels for insertion or removal of the flexible tubing. The front plate may be transparent. The control valves (8) operate by simply pressing on the tubing in the support channels to block flow, without invasion of the flow path. The tubing sets can be easily replaced, cleaned or sterilised. The invention is useful in a range of controlled-flow processes e.g. chromatography and filtration.

GAS PHASE OXIDATION CATALYST WITH LOW CHARGE TRANSPORT ACTIVATION ENERGY

A catalyst for the gas phase oxidation of organic hydrocarbons comprises a multielement oxide which comprises at least one transition meal such as vanadium, wherein the catalyst has a charge transport activation energy Ec at a temperature of 375 to 425°C of less than 0 kJ/mol. The catalyst serves for preparation of maleic anhydride.

THIN FILM TUBE REACTOR

A thin film tube reactor comprising a tube having a longitudinal axis, an inner cylindrical surface, a closed end and an open end, wherein the tube is rotatable about the longitudinal axis and wherein the angle of the longitudinal axis relative to the horizontal is variable between about 0 degrees and about 90 degrees.

SURFACE FUNCTIONALIZATION

CA 3069742 Abstract The invention pertains to methods of functionalizing the surface of an enclosed microfluidic channel. The methods comprise exposing a portion of an unmodified surface of the microfluidic channel to a bifunctional crosslinker, activating said crosslinker to create a crosslinked surface, and exposing the crosslinked surface of a surface hydrophobicity modifying molecule to create a functionalized surface. Date Recue/Date Received 2021-01-08 ...

INTEGRATED SOLAR MICRO-REACTORS FOR HYDROGEN SYNTHESIS VIA STEAM METHANE REFORMING

A reactor for steam-methane reforming is adapted to be received in a tube on a focal axis of a parabolic trough. The reactor may comprise an array of micro-reactors interconnected by a water manifold, a gas manifold, a syngas manifold, and at least one steam-methane reforming chamber configured for reforming steam and methane into syngases, the micro-reactors having a vaporization portion for producing steam. Radiation plates may extend on sides of the array of micro-reactors. Glazing may face and be spaced apart from a portion of the array of micro-reactors including at least one steam-methane reforming chamber, the glazing being conductively connected to the radiation plates for heat transfer therebetween, the at least one glazing allowing light from the parabolic trough to pass therethrough to reach the array of micro-reactors.

POSITIONAL TRACKING AND ENCODING IN MICROFLUIDIC DEVICES

The invention relates to methods and compositions useful for routing and tracking multiple mobile units within a microfluidic device. Mobile units may be routed through a plurality of chemical environments, and the mobile units may be tracked to determine the path and/or environments that the mobile units have routed through. Mobile units may be routed in accordance with a predetermined algorithm. Mobile units may be routed through microfluidic devices in ordered flow. Absolute or relative position of a unit inside a microfluidic device, e.g. within an ordered set of units, may be used to identify the routing path history of the unit.

Diverging film reacting device

This invention provides a diverging film reacting device which comprises a reacting pipe, a film and a blowing pipe. The reacting pipe, the film and the blowing pipe are arranged in order either from the inside to the outside, or from the outside to the inside. This film reacting device is characterized in that the cross sectional area of the reacting pipe increases from the front end to the back end in order that a flowing speed of raw gas in the reacting pipe decreases from the front end to the back end, which extends the time when the raw gas stays in the reacting pipe to increase the ratio of the raw gas in reaction. This invention further makes the cross sectional area of the blowing pipe decrease from the front end to the back end so that a flowing speed of blowing gas in the blowing pipe increases from the front end to the back end, accelerating the speed of removing generated gas that enters the blowing pipe through the film after the raw gas went through the reaction. As a result ...

Process for producing tetra-hydro alkyl substituted indanes

The present invention relates to an improved process for producing tetra-hydro alkyl substituted indanes which are used in the synthesis of fragrance ingredients for perfumery applications.

System and method for emulsion breaking and phase separation by droplet adhesion

Emulsion breaking and phase separation is achieved by droplet adhesion. An emulsion breaking device includes a channel having distinct adjacent zones with distinctly different surface wettability characteristics, namely, solvophilic and solvophobic surfaces. The device is positioned such that the upstream portion of the device is configured to be wetted by the continuous phase of the emulsion, and the downstream portion of the device is configured to be wetted by the dispersed phase of the emulsion. As the emulsion flows from the upstream zone to the downstream zone, the change in surface wettability characteristics promotes adhesion of the dispersed phase as the dispersed phase wets the surface of the downstream portion of the channel, which results in breaking of the emulsion. Subsequent collection of the broken emulsion in a collection vessel results in separation of the disparate phases to facilitate their recapture and recycling.

SURFACE FUNCTIONALIZATION

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

REACTOR SYSTEM AND PROCESS FOR FLOW-THROUGH REACTIONS

IMPROVED PROCESS-INTENSIFIED FLOW REACTOR

A flow reactor has a module having a process fluid passage with an interior surface, a portion of the passage including a cross section along the portion having a cross-sectional shape, and a cross-sectional area with multiple minima along the passage. The cross-sectional shape varies continually along the portion and the interior surface of the portion includes either no pairs of opposing flat parallel sides or only pairs of opposing flat parallel sides which extend for a length of no more than 4 times a distance between said opposing flat parallel sides along the portion and the portion contains a plurality of obstacles distributed along the portion.

МИКРОФЛЮИДНЫЕ УСТРОЙСТВА ДЛЯ ПОЗИЦИОННОГО ОТСЛЕЖИВАНИЯ И КОДИРОВАНИЯ

Verfahren zur Synthese von Carbonsäureamiden

Die Erfindung stellt ein Verfahren zur Synthese von Carbonsäureamiden zur Verfügung, umfassend die Schritte: a) Bereitstellen eines Carbonsäureesters der Formel RCOOR' und Ammoniak (NH3), b) Mischen des Carbonsäureesters der Formel RCOOR' und des Ammoniaks (NH3), und c) Reagieren des Carbonsäureesters der Formel RCOOR' und des Ammoniaks (NH3) zu einem Carbonsäureamid der Formel RCONH2 und R'OH, dadurch gekennzeichnet, dass der Ammoniak in Schritt a) in flüssiger Form oder in überkritischer Form zugeführt wird. Die Erfindung stellt weiterhin eine Anlage zur Durchführung des erfindungsgemäßen Verfahrens zur Verfügung.

Verfahren zur kontinuierlichen Herstellung von Biomethanoldiesel

Die Erfindung betrifft ein Verfahren zur kontinuierlichen Herstellung von Biomethanoldiesel in kleineren Mengen, beispielsweise für die lokale Energieversorgung in der Landwirtschaft. DOLLAR A Das Problem der Erfindung besteht darin, ein kontinuierliches Verfahren zur Herstellung von Biomethanoldiesel zu entwickeln, das unabhängig vom Produktionsvolumen minimale Investitionen bei der Apparatetechnik erfordert, in Kleinstanlagen schon ab einem Produktionsvolumen von 0,05 kt/a wirtschaftlich durchführbar und einfach handhabbar ist. DOLLAR A Erfindungsgemäß werden die frisch gepressten Öle vor dem eigentlichen Umesterungsprozess mit Methanol in der Mikroreaktorkaskade zweimal gewaschen und dabei Säurezahlen SZ 0,1 realisiert. DOLLAR A Durch die dem Umesterungsprozess vorgeschaltete Waschkaskade werden die freien Fettsäuren neben anderen Pflanzeninhaltstoffen aus den Ölen entfernt. Sowohl zur Waschung als auch zur Umesterung werden Mikroreaktoren benutzt. Das Verfahren arbeitet bei Temperaturen ...

Systes and methods for thermally actuated flow control

Monolithic body

Positional tracking and encoding in microfluidic devices

The invention relates to methods and compositions useful for routing and tracking multiple mobile units within a microfluidic device. Mobile units may be routed through a plurality of chemical environments, and the mobile units may be tracked to determine the path and/or environments that the mobile units have routed through. Mobile units may be routed in accordance with a predetermined algorithm. Mobile units may be routed through microfluidic devices in ordered flow. Absolute or relative position of a unit inside a microfluidic device, e.g. within an ordered set of units, may be used to identify the routing path history of the unit.

APPARATUS, SYSTEMS, AND METHODS FOR CONTINUOUS MANUFACTURING OF NANOMATERIALS AND HIGH PURITY CHEMICALS

A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided. The system having a feed pump that is adapted to pump a first feed stream downstream at an actively automatically controlled rate. An in-line mixer positioned to receive the first feed stream from the feed pump and a second feed stream from a feed line, the in-line mixer adapted to mix the first and second feed streams to achieve a substantially homogeneous mixture. The system also having a high pressure pump positioned to receive the substantially homogeneous mixture from the in-line mixture, the high pressure pump adapted to pressurize the first and second feed streams to an elevated pressure of at least 35 MPa; and a microreactor having a minimum channel dimension of 500 microns or less downstream of the high pressure pump.

GAS DRIVEN FLUID TRANSPORT

Fluid transport approaches are described that operate without the need for precise displacement of an actuator and with little or no sensing in the flow path. In certain implementations, a gas phase in a fluid reservoir is compressed by a pressure source such that releasing the pressure, such as by opening a valve to an intermediary conduit, displaces fluid to the intermediary chamber. Closing that fluid path and opening a different fluid path to a chamber at ambient temperature causes the fluid to be displaced to the chamber.

METHODS OF GENERATING MICROPARTICLES AND POROUS HYDROGELS USING MICROFLUIDICS

Provided herein are methods utilizing microfluidics for the oxygen-controlled generation of microparticles and hydrogels having controlled microparticle sizes and size distributions and products from provided methods. The included methods provide the generation of microparticles by polymerizing an aqueous solution dispersed in a non-aqueous continuous phase in an oxygen-controlled environment. The process allows for control of size of the size of the aqueous droplets and, thus, control of the size of the generated microparticles which may be used in biological applications.

CONTINUOUS PROCESS FOR THE PREPARATION OF TRAZODONE

PHOTOREACTION MICRO REACTOR

A photoreaction micro reactor (101) comprises a housing upper part (102), a lid plate (103) made from a material that allows the passage of light, a flow path plate (104) that suppresses light reflection and is made from a material with high thermal conductivity, and a housing lower part (105). Light is irradiated through a window of the housing upper part (102) and through the lid plate (103) onto a flow path (109) of the flow path plate (104). The lid plate (103) made from the material that allows the passage of light is welded to form an integrated body with the flow path plate (104) that suppresses light reflection and is made from a material with high thermal conductivity.

Flow-through reactors for the continuous quenching of peroxide mixtures and methods comprising the same

This disclosure relates to a highly efficient and safe reactor for the continuous quenching of peroxide mixtures generated during the reaction of unsaturated compounds with ozone, which minimizes the amount of highly reactive peroxides accumulated in the reactor at any given time. The reactor may be modified to allow for expansion to accommodate the quenching parameters of a wide variety of ozonolysis reactions and flow rates. The reactor may be constructed from highly pressure rated stainless steel for maximum durability, safety, and economic practicality while increasing the safety of peroxide quenching, thus allowing tighter process control and improved product yields. This disclosure also related to methods for quenching ozonides.

MULTI-PHASE OSCILLATORY FLOW REACTOR

According to some aspects, described herein is an automated droplet-based reactor that utilizes oscillatory motion of a droplet in a tubular reactor under inert atmosphere. In some cases, such a reactor may address current shortcomings of continuous multi-phase flow platforms.

物理的転移及び/又は化学的転移の少なくとも一つのパラメーターを決定するための方法及び装置

... この方法によれば、転移を受けるのに好適な物理化学的系を流れ手段(8)に流入させると共に、該流れ手段の壁部の外部周囲を同じ温度に維持し(ただし、該流れ手段の2つの分離した箇所間に少なくとも存在する観測区域を除く)、該物理化学的系の温度の少なくとも一つの空間分布を該観測区域に沿って特に赤外線カメラで表示し、これから該パラメーター又は各パラメーターを該温度空間配置又は各温度空間配置を使用して推定する。 ...

НЕПРЕРЫВНЫЙ СПОСОБ ПОЛУЧЕНИЯ ВЫСОКОРАЗВЕТВЛЕННЫХ ПОЛИМЕРОВ НА ОСНОВЕ МОНОЭТИЛЕННЕНАСЫЩЕННОЙ МОНО- ИЛИ ДИКАРБОНОВОЙ КИСЛОТЫ, СОДЕРЖАЩЕЙ ОТ 3 ДО 8 АТОМОВ УГЛЕРОДА, ИЛИ ЕЕ АНГИДРИДОВ И ЕЕ СОЛЕЙ

FIELD: chemistry.SUBSTANCE: invention relates to a continuous process for the preparation of highly branched ethylene unsaturated monocarboxylic acid homo- or copolymers. Continuous process for the preparation of homo- or copolymers of a monoethylene unsaturated monocarboxylic acid containing from 3 to 8 carbon atoms, or its salts (monomer A) is carried out with free radical polymerization of monomer A and optionally free radical polymerization of water-soluble ethylenically unsaturated monomers (monomer B), other than monomer A, in an aqueous medium in the presence of at least one water-soluble initiator. Method differs in that it includes the following stages: I) optionally continuous dosing of the monomer solution(s) and the initiator solution into the mixing device comprising at least one micromixer and mixing the reactants in the mixing device, II) carrying out continuous free radical polymerization in at least one segment of a tubular reactor at a temperature from 180 °C to 300 °C, where the tubular reactor has a specific surface area of more than 50 m/mand where the entire reactor system contains at least one pressure regulating device, the polymerization is carried out in the absence of traditional chain transfer agents, and wherein the polymer has a degree of branching equal to or higher than 7 mol% relative to the total amount of monomers. Declared polymer obtained by the method, and its application.EFFECT: obtaining highly branched polymers with a minimum content of heteroatoms, which are used as cross-linking agents.17 cl, 3 tbl, 3 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 678 304 C2 (51) МПК C08F 2/01 (2006.01) C08F 2/10 (2006.01) C08F 2/16 (2006.01) C08F 20/00 (2006.01) B01F 13/00 (2006.01) B01J 19/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C08F 2/01 (2018.08); C08F 2/10 (2018.08); C08F 2/16 (2018.08); C08F 20/00 (2018.08); B01F 13/00 (2018.08); B01J 19/00 (2018.08) (21)(22) Заявка: ...

Surface functionalization

CONTINUOUS PROCESS FOR THE PREPARATION OF TRAZODONE

The present invention relates to an improved process for the preparation of trazodone. In particular, the present invention relates to a continuous process for the preparation of trazodone. More in particular, the present invention relates to a new method for the preparation of trazodone, said method comprising at least one step consisting of a continuous process performed in a flow reactor.

METHOD AND APPARATUS FOR PRODUCING CHEMICALS FROM A METHANE-CONTAINING GAS

An apparatus and a method for producing chemicals from a methane-containing gas are provided. More specifically, the method and an apparatus make use of heterogeneous catalysis, beginning with the partial oxidation of methane to produce synthesis gas followed by a reaction, such as a Fischer-Tropsch reaction, to produce the chemicals.

HEAVY FOSSIL HYDROCARBON CONVERSION AND UPGRADING USING RADIO-FREQUENCY OR MICROWAVE ENERGY

Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.

POLYMERIZATION REACTIONS WITHIN MICROFLUIDIC DEVICES

The present invention generally relates to polymerization reactions within microfluidic devices. In certain cases, the invention allows for precise control of the polymerization of different types of monomers to form a copolymer by controlling the steps of polymerization and/or controlling the addition of monomers at various time scales within a microfluidic droplet and/or a microfluidic environment, often to a degree that is unattainable by other block polymerization techniques. For example, in one aspect, the present invention is directed to systems and methods for producing polymers such as block copolymers, gradient polymers, random copolymers, etc. For instance, in one set of embodiments, a first monomer contained within a channel, such as a microfluidic channel, is allowed to polymerize to form a first block of a block copolymer. Additional blocks may be added, for example, by flowing the first block and other monomers through a second channel (which may be an extension of the first ...

DEVICE USEFUL FOR HYDROGENATION REACTIONS (III)

The present invention relates to a device for treatment of material transported through the device comprising at least one porous element consisting of specific solid metallic structure which allows cross-flow of the material through the porous element and wherein the porous element is coated by a non-acidic metal oxide which is impregnated by palladium (Pd).

Methods of catalytic hydrogenation for ethylene glycol formation

Embodiments described herein generally relate to hydrogenation catalysts, syntheses of hydrogenation catalysts, and apparatus and methods for hydrogenation. Methods for forming a hydrogenation catalyst may include mixing a silica generating precursor with a copper precursor and adding an ammonium salt to an end pH of between about 5 to about 9. Methods for hydrogenating an oxalate may include forming a reaction mixture by flowing a hydrogenation catalyst to a reactor, flowing a hydrogen source to the reactor, and flowing an oxalate to the reactor, wherein the hydrogenation catalyst has a particle size between about 10 nm to about 40 nm. Methods may further include reacting the oxalate to form ethylene glycol.

Enhanced microchannel or mesochannel devices and methods of additively manufacturing the same

Chemical processors are configured to reduce mass, work in conjunction with solar concentrators, and/or house porous inserts in microchannel or mesochannel devices made by additive manufacturing. Methods of making chemical processors containing porous inserts by additive manufacturing are also disclosed.

Process for the preparation of N-alkyl-nitratoethylnitramines

The present invention relates to a continuous process for the preparation of N-alkyl- nitratoethylnitramines (e.g. NENA compounds, DINA).

Methods of generating microparticles and porous hydrogels using microfluidics

Provided herein are methods utilizing microfluidics for the oxygen-controlled generation of microparticles and hydrogels having controlled microparticle sizes and size distributions and products from provided methods. The included methods provide the generation of microparticles by polymerizing an aqueous solution dispersed in a non-aqueous continuous phase in an oxygen-controlled environment. The process allows for control of size of the size of the aqueous droplets and, thus, control of the size of the generated microparticles which may be used in biological applications.

SURFACE FUNCTIONALIZATION

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

MICROREACTOR

A micro reactor (100) is provided with: a reaction flow channel (110) having circulated therein a fluid as a reaction object; and a medium flow channel (120), which is provided parallel to the reaction flow channel (110), and which has circulated therein a heat medium that exchanges heat with the fluid in the reaction flow channel (110). The cross-sectional area of the medium flow channel (120) adjacent to a reaction flow channel (110) portion having relatively large heat generation or heat absorption due to the reaction of the fluid is smaller than the cross-sectional area of the medium flow channel (120) portion adjacent to a reaction flow channel (110) portion having relatively small heat generation or heat absorption due to the reaction of the fluid.

FLOW REACTOR SYNTHESIS OF POLYMERS

A flow reactor system and polymerization apparatus and methods having tubing useful as a polymerization chamber. The polymerization apparatus comprises an amount of tubing having at least one inlet and at least one mixing chamber, and an outlet. The polymerization apparatus further comprises a pressure regulating unit positioned at the outlet of the amount of tubing and configured to monitor a change in pressure during polymerization or during a collection step of polymerized material as well as a controller configured to use information from the pressure regulating unit to cease introduction of the one or more monomers. The methods may comprise forming a salt of a polymerized monomer (such as an aniline) with an acid (such as dinonylnaphthalene sulfonic acid) within the length of tubing in the flow reactor.

Integrated micro-channel reaction device and method for preparing 2-chloroethyl diphosphate diester by utilizing reaction device

Improved process-enhanced flow reactor

SEGMENTED FLOW BIOFILM REACTOR

A segmented flow biofilm reactor is provided which comprises at least one capillary member, at least one reservoir for a liquid phase, and at least one reservoir for a gaseous phase, wherein the at least one reservoir for the liquid phase, and the at least one reservoir for the gaseous phase are in fluid connection with the at least one capillary member. In addition, a method for converting a substrate to a product using a biofilm as biocatalyst within at least one capillary member is provided, wherein at least one liquid phase and a gaseous phase are flowing through the at least one capillary member bearing the biofilm biocatalyst in a segmented fashion.

GAS PHASE OXIDATION CATALYST WITH LOW CHARGE TRANSPORT ACTIVATION ENERGY

A catalyst for the gas phase oxidation of organic hydrocarbons comprises a multielement oxide which comprises at least one transition meal such as vanadium, wherein the catalyst has a charge transport activation energy Ec at a temperature of 375 to 425°C of less than 0 kJ/mol. The catalyst serves for preparation of maleic anhydride.

Continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts

The present invention provided a continuous flow process for the synthesis of phenylhydrazine salts and substituted phenylhydrazine salts. Diazotization, reduction, acidic hydrolysis and salifying with acids are innovatively integrated together. Using acidic liquids of aniline or substituted aniline, diazotization reagents, reductants and acids as raw materials, phenylhydrazine derivative salts is obtained through the synthesis process, which is a three-step continuous tandem reaction including diazotization, reduction, acidic hydrolysis and salifying. The described synthesis process is a kind of integrated solutions, which is carried out in an integrated reactor. The feed inlets of the integrated reactor are continuously filled with raw materials. In the integrated reactor, diazotization, reduction, acidic hydrolysis and salifying are carried out continuously and orderly, and phenylhydrazine salts or substituted phenylhydrazine salts is obtained in the outlet of the integrated reactor ...

Apparatus and methods for fluid processing and flow control

Fluid processing apparatus has a prefabricated branched network of flexible tubing, for conducting process fluid between process elements of the apparatus, and control valves. A tubing support has opposable front and rear plates which define a pattern of support channels between them in which the flexible tubing network lies, so that the support channels limit or prevent expansion of the flexible tubes. Standard non-reinforced tubing can then be used for high-pressure work. The support body plates can be separated to open the channels for insertion or removal of the flexible tubing. The front plate may be transparent. The control valves operate by simply pressing on the tubing in the support channels to block flow, without invasion of the flow path. The tubing sets can be easily replaced, cleaned or sterilized. The invention is useful in a range of controlled-flow processes e.g. chromatography and filtration.

METHOD AND FACILITY FOR DETERMINING AT LEAST ONE PARAMETER OF A PHYSICAL AND/OR CHEMICAL TRANSFORMATION

IMPROVED PROCESS-INTENSIFIED FLOW REACTOR

A flow reactor has a module having a process fluid passage with an interior surface, a portion of the passage including a cross section along the portion having a cross-sectional shape, and a cross-sectional area with multiple minima along the passage. The cross-sectional shape varies continually along the portion and the interior surface of the portion includes either no pairs of opposing flat parallel sides or only pairs of opposing flat parallel sides which extend for a length of no more than 4 times a distance between said opposing flat parallel sides along the portion and the portion contains a plurality of obstacles distributed along the portion.

Piercing device

Flow reactor synthesis of polymers

FLOW REACTOR SYNTHESIS OF POLYMERS A flow reactor system (100) and methods having tubing (70) useful as polymerization chamber. The flow reactor (100) has at least one inlet and at least one mixing chamber (30), and an outlet (80). The method includes providing two phases, an aqueous phase (10) and a non-aqueous phase (20) and forming an emulsion for introduction into the flow reactor (100).

Surface functionalization

This invention is in the field of surface modification. In particular, the invention relates to the surface modification of microfluidic devices to alter surface hydrophobicity characteristics.

PROCESS FOR THE PREPARATION OF N-ALKYL-NITRATOETHYLNITRAMINES

The present invention relates to a continuous process for the preparation of N-alkyl- nitratoethylnitramines (e.g. NENA compounds, DINA).

MICROFLUIDIC CASSETTE FOR SYNTHESISING A RADIOTRACER AND METHOD FOR SYNTHESISING A RADIO-TRACER WITH SUCH A CASSETTE

La présente demande concerne une cassette microfluidique de synthèse d'un radio- traceur comportant un circuit microfluidique dans une carte de support qui comporte au moins une prise d'alimentation par une fiole (Pf), au moins un port isotope (IP), au moins une chambre de réaction (R1, R2, R3, R4), au moins une chambre de mélange (M1, M2, M3, M4), au moins une chambre de formulation (FC), et au moins une prise de connexion pour une seringue (SP), reliés entre eux par des capillaires. Elle concerne aussi un procédé de synthèse d'un radio-traceur dans une telle cassette.

FLOW REACTOR SYNTHESIS OF POLYMERS

A flow reactor system and polymerization apparatus and methods having tubing useful as a polymerization chamber. The polymerization apparatus comprises an amount of tubing having at least one inlet and at least one mixing chamber, and an outlet. The polymerization apparatus further comprises a pressure regulating unit positioned at the outlet of the amount of tubing and configured to monitor a change in pressure during polymerization or during a collection step of polymerized material as well as a controller configured to use information from the pressure regulating unit to cease introduction of the one or more monomers. The methods may comprise forming a salt of a polymerized monomer (such as an aniline) with an acid (such as dinonylnaphthalene sulfonic acid) within the length of tubing in the flow reactor.

FLOW PATH CHIP

... [Object] An object of the present invention is to provide a flow path chip that is capable of narrowing or removing a gap between a porous body and a base material in particular when compared to the related art, and is capable of a high-precision fluid treatment. [Solution] A flow path chip (1) according to the present invention comprises a first base material (10), a second base material (20), a concave-shaped treatment flow path (15) that is formed in the first base material, a porous body (41) that is arranged in the treatment flow path (15), and a biasing member (42) that is disposed between the porous body (41) and the second base material (20) to press the porous body (41) onto the first base material (10).

MICROREACTOR FOR PHOTOREACTIONS

A microreactor for photoreactions includes a housing upper part, a lid plate made of a material that allows transmission of light, a flow path plate made of a material that suppresses light reflection and has a high thermal conductivity, and a housing lower part. Light is applied through a window of the housing upper part and the lid plate to a flow path of the flow path plate. The lid plate made of the material that allows transmission of light and the flow path plate made of the material that suppresses light reflection and has a high thermal conductivity are welded each other to form an integrated body.

TUBULAR FLOW REACTOR

A tubular flow reactor which comprises a plurality of inflow channels for introducing at least two kinds of fluids to cause a reaction; a reaction tube having an internal space for merging the fluids and causing the merged fluids to flow through to cause a reaction; an outflow channel for discharging the reaction product from the reaction tube; and a rod-shaped ultrasonic emitter placed at the flow-merging portion of the internal space of the reaction tube; wherein the inflow channels and the outflow channel are connected to the reaction tube such that their respective internal spaces communicate with the internal space of the reaction tube; and an ultrasonic wave can be emitted from the rod-shaped ultrasonic emitter to the fluid passing through the reaction tube.

Surface functionalization

Continuous process for the preparation of trazodone

The present invention relates to an improved process for the preparation of trazodone. In particular, the present invention relates to a continuous process for the preparation of trazodone. More in particular, the present invention relates to a new method for the preparation of trazodone, said method comprising at least one step consisting of a continuous process performed in a flow reactor.

FILTER FOR CHEMICAL REACTORS

A chemical reactor implemented on a substrate comprises an inlet for receiving a fluid and/or a gas, whereby the inlet has a first depth dhigh and has been adjusted to accommodate a capillary, comprises a filter element for reducing or preventing that materials cause a blockage in the fluid supplied and/or the gas supplied in a part of the chemical reactor located further away, and comprises a part located further away for transporting and/or processing the fluid and/or the gas, whereby the part located further away has a depth dlow smaller than the depth dhigh of the inlet. The filter element comprises a first duct part and a second duct part, whereby the first duct part is positioned closer up against the inlet than the second duct part, the first duct part is deeper than the second duct part, the first duct part has a diverging width and is free from pillar structures, and the second duct part is filled with filter pillars.

MICROREACTOR

A micro reactor (100) is provided with: a reaction flow channel (110) having circulated therein a fluid as a reaction object; and a medium flow channel (120), which is provided parallel to the reaction flow channel (110), and which has circulated therein a heat medium that exchanges heat with the fluid in the reaction flow channel (110). The cross-sectional area of the medium flow channel (120) adjacent to a reaction flow channel (110) portion having relatively large heat generation or heat absorption due to the reaction of the fluid is smaller than the cross-sectional area of the medium flow channel (120) portion adjacent to a reaction flow channel (110) portion having relatively small heat generation or heat absorption due to the reaction of the fluid.

CONTINUOUS PROCESS FOR THE SYNTHESIS OF GRAFT POLYMERS BASED ON POLYETHERS

The invention relates to a continuous process for the preparation of amphiphilic graft polymers, wherein a vinyl ester component(B) composed of vinyl acetate and/or vinyl propionate (B1) and, if desired, a further ethylenically unsaturated monomer (B2), is polymerized in the presence of a polyalkylene oxide (A), a free radical-forming initiator (C) and, if desired, an additive(D), at a mean polymerization temperature at which the initiator (C) has a decomposition half-time of from 1to 500 min, in at least one tubular reactor segment with a feed side and an outlet side, through which the reaction mixture comprising at least a part of component (A) to (C), and if desired (D), streams. The invention further relates to an inventive amphiphilic graft polymer and the use thereof.

CONTINUOUS PROCESS FOR THE MANUFACTURE OF HIGHLY-BRANCHED POLYMERS BASED ON C3-C8 MONOETHYLENICALLY UNSATURATED MONO- OR DICARBOXYLIC ACID OR ON THE ANHYDRIDES AND SALTS THEREOF

The present invention relates to a continuous process for the manufacture of highly-branched homo- or copolymers of C3-C8 ethylenically unsaturated mono- or dicarboxylic acid as well as the anhydrides and salts thereof (monomer A) by means of free-radical polymerization of monomer A and optionally water-soluble, monethylenically unsaturated comonomers (monomer B) in an aqueous medium in the presence of at least one water-soluble initiator, wherein the polymerization takes place in at least one tubular reactor segment.

PROCESS AND INSTALLATION OF DETERMINATION Of AT LEAST a PARAMETER Of a PHYSICAL AND/OR CHEMICAL TRANSFORMATION

Selon ce procédé : - on fait s'écouler un système physico-chimique, propre à subir ladite transformation, dans un organe d'écoulement (8), tout en maintenant à une même température la périphérie extérieure de la paroi de cet organe d'écoulement, à l'exception d'une zone de visualisation, au moins entre deux points distants de celui-ci ; - on visualise, notamment grâce à une caméra à infrarouge (10), au moins une répartition spatiale de la température du système physico-chimique le long de cette zone de visualisation ; - on en déduit le ou chaque paramètre, à partir de la ou chaque répartition spatiale de température.

THIN FILM TUBE REACTOR

A thin film tube reactor comprising a tube having a longitudinal axis, an inner cylindrical surface, a closed end and an open end, wherein the tube is rotatable about the longitudinal axis and wherein the angle of the longitudinal axis relative to the horizontal is variable between about 0 degrees and about 90 degrees.

SYSTEM AND METHOD FOR MAKING QUANTUM DOTS

Embodiments of the present disclosure provide for methods of making quantum dots (QDs) (passivated or unpassivated) using a continuous flow process, systems for making QDs using a continuous flow process, and the like. In one or more embodiments, the QDs produced using embodiments of the present disclosure can be used in solar photovoltaic cells, bio-imaging, IR emitters, or LEDs.

High-Pressure Homogenizer and Method for Manufacturing Graphene Using the Same

Provided a high-pressure homogenizer comprising a channel module comprising a microchannel through which an object for homogenization passes, wherein the microchannel is provided with a first flow channel and a second flow channel sequentially arranged along the direction through which the object passes, the first flow channel is provided with a plurality of first baffles disposed so as to partition the microchannel into a plurality of spaces, the second flow channel is provided with a plurality of second baffles disposed so as to partition the microchannel into a plurality of spaces, and at least one of the first baffles is provided to be positioned between two adjacent second baffles.

METHOD FOR THE CONTINUOUS PRODUCTION OF BIOMETHANOL DIESEL

The invention relates to a method for the continuous production of biomethanol diesel in smaller amounts, for example for local energy supply on the land. The aim of the invention is to develop a continuous method for the production of biomethanol diesel, which requires minimal investment in equipment, independent of the production volumes, which can be economically carried out and simply managed in the smallest plants from a production volume of 0.05 kt/a upwards. According to the invention the freshly pressed oils are washed twice in the microreactor cascade to give an acid number SZ ¿ 0.1 before the transesterification process with methanol. As a result of the washing cascade before the transesterification process the free fatty acids and other plant materials are removed from the oils. Microreactors are used for both the washing process and the transesterification. The method operates at temperatures of 65 °C. The transesterification itself is two-staged. The unit can also be used for ...

Berty-Reaktor und Bausatz für einen solchen

Es wird ein Bausatz (45) für einen Berty-Reaktor (1) angeben. Der Bausatz (45) umfasst ein Gehäuse (2), das einen Aufnahmeraum (5) druckdicht umschließt, und eine Strömungsmaschine (9), die ein Laufrad (8) zur Erzeugung einer Kreisströmung in dem Aufnahmeraum (5) umfasst. Der Bausatz (45) umfasst mehrere Katalysatorkörbe (6) oder Teile zum Aufbau verschiedener Katalysatorkörbe (6). Jeder der Katalysatorkörbe (6) weist eine ringförmige Korbwand auf, die einen in einer Axialrichtung durchströmbaren freien Innenraum (20) zur Aufnahme eines Katalysators umschließt. In dem Innenraum (20) eines jeden Katalysatorkorbs (6) sind jeweils zwei Siebe (28, 29) angeordnet oder anordenbar, die ein mit dem Katalysator zu befüllendes Füllvolumen (30) begrenzen. Die Katalysatorkörbe (6) sind gegeneinander vertauschbar in den Aufnahmeraum (5) einsetzbar, so dass zwischen dem Katalysatorkorb (6) und einer Umfangswand (21) des Gehäuses (2) ein Abstand gebildet ist. Die Katalysatorkörbe (6) unterscheiden sich ...

Heavy fossil hydrocarbon conversion and upgrading using radio-frequency or microwave energy

Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.

Apparatus and methods for fluid processing and flow control

Fluid processing apparatus has a prefabricated branched network of flexible tubing (2), for conducting process fluid between process elements of the apparatus, and control valves (8). A tubing support (1) has opposable front and rear plates (6, 7) which define a pattern of support channels (60) between them in which the flexible tubing network lies, so that the support channels limit or prevent expansion of the flexible tubes. Standard non-reinforced tubing can then be used for high-pressure work. The support body plates (6, 7) can be separated to open the channels for insertion or removal of the flexible tubing. The front plate may be transparent. The control valves (8) operate by simply pressing on the tubing in the support channels to block flow, without invasion of the flow path. The tubing sets can be easily replaced, cleaned or sterilised. The invention is useful in a range of controlled-flow processes e.g. chromatography and filtration.

Flow reactor synthesis of polymers

FLOW REACTOR SYNTHESIS OF POLYMERS A flow reactor system (100) and methods having tubing (70) useful as polymerization chamber. The flow reactor (100) has at least one inlet and at least one mixing chamber (30), and an outlet (80). The method includes providing two phases, an aqueous phase (10) and a non-aqueous phase (20) and forming an emulsion for introduction into the flow reactor (100).

Nanoporous thin film and method for fabricating the same

ONE-STEP UREA SYNTHESIS SYSTEM AND METHOD

The present invention provides a one-step urea synthesis system. In one embodiment, the system comprises a magnetic induction zone, a reaction chamber being disposed in and between the magnetic induction zone, a plurality of platforms being disposed inside the reaction chamber, catalyst/catalyst support micro-reactors grown on the bottom part of the plurality of platforms, a reactant gases inlet positioned at the bottom part of the reaction chamber for taking in reactant gases, wherein after the reactant gases enter the reaction chamber, they flow upward and reacts with the catalyst/catalyst support micro- reactors to form molten urea; and an outlet positioned at the bottom part of the reaction chamber for discharging the molten urea. The present invention also provides a method for one-step synthesis of urea.

MICROREACTOR FOR PHOTOREACTIONS

A microreactor for photoreactions includes a housing upper part, a lid plate made of a material that allows transmission of light, a flow path plate made of a material that suppresses light reflection and has a high thermal conductivity, and a housing lower part. Light is applied through a window of the housing upper part and the lid plate to a flow path of the flow path plate. The lid plate made of the material that allows transmission of light and the flow path plate made of the material that suppresses light reflection and has a high thermal conductivity are welded each other to form an integrated body.

APPARATUS, SYSTEMS, AND METHODS FOR CONTINUOUS MANUFACTURING OF NANOMATERIALS AND HIGH PURITY CHEMICALS

A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided. 158-. (canceled)59. A method for continuously processing at least two liquid feed streams , comprising:pumping a first feed stream to a mixer;flowing a second feed stream to the mixer without pumping the second feed stream to the mixture;mixing the first and second feed streams to achieve a substantially homogeneous mixture; andpumping the substantially homogeneous mixture to a high pressure pump,wherein mixing the first and second feed streams to achieve the substantially homogenous mixture includes mixing the first and second feed streams with the mixer at a location that is upstream of the high pressure pump and upstream of a component arranged between the mixer and the high pressure pump, andwherein the component is selected from one of the following: a conduit, a tank, a valve, a pump, a filter, a screen, a sensor, or a port.60. The method of claim 59 , further comprising:pressurizing the substantially homogeneous mixture within the high pressure pump to an elevated pressure; anddelivering the substantially homogeneous mixture to a microreactor downstream from the high pressure pump to cause the first and second feed streams to interact within the microreactor at a nanoscale level.61. The method of claim 60 , wherein:pressurizing the substantially homogeneous mixture within the high pressure pump includes pressurizing the substantially homogeneous mixture to an elevated pressure of at least 35 MPa; anddelivering the substantially homogeneous mixture to the microreactor includes delivering the substantially homogeneous mixture to a microreactor having a minimum channel dimension of equal to or less than 500 microns.62. The method of claim 60 , wherein:the first feed stream includes a first reactant;the second feed stream includes a second reactant; andthe method further comprises adjusting ...

SYSTEMS AND METHODS FOR THERMALLY ACTUATED FLOW CONTROL

Various implementations provide an inherently safer design feature for microchannel reactors that provides temperature control at the individual channel level. This approach relies on bimetallic strips embedded within the combustion channel, forming a thermally-actuated “valve”. Bimetallic strips convert a temperature change into a mechanical displacement. Heating the strip increases its deflection and thereby restricts flow in the combustion channels, which consequently reduces the rate of heat generation. The thermally-actuated valve is not limited to use in microchannel reactors and may be used in other structures for which thermally actuated flow control is desired, according to some implementations. 1. A thermally actuated flow control system comprising:a first linear array of bimetallic strips disposed on a first wall of a channel; anda second linear array of bimetallic strips disposed on a second wall of the channel, the first and second walls being opposite and in a facing relationship with each other relative to an axis of fluid flow through the channel, each bimetallic strip comprises a fixed end and a free end,', 'the fixed ends of the bimetallic strips in the first array are coupled to the first wall,', 'the fixed ends of the bimetallic strips in the second array are coupled to the second wall,', 'each bimetallic strip comprises a first metal strip having a first thermal expansion coefficient and a second metal strip having a second thermal expansion coefficient, the first and second metal strips being fixedly coupled together, and the first thermal expansion coefficient being higher than the second thermal expansion coefficient, wherein the first metal strip is coupled to the wall, and the second metal strip extends towards the axis of fluid flow of the channel, and', 'a deflection of the free ends of the first array of bimetallic strips away from the first wall and the free ends of the second array of bimetallic strips away from the second wall ...

Flow reactor synthesis of polymers

A flow reactor system and methods having tubing useful as polymerization chamber. The flow reactor has at least one inlet and at least one mixing chamber, and an outlet. The method includes providing two phases, an aqueous phase and a non-aqueous phase and forming an emulsion for introduction into the flow reactor.

Microfluidic Liposome Synthesis, Purification and Active Drug Loading

Microfluidic methods and systems are provided for continuous flow synthesis and active loading of liposomes, which include a liposome formation region configured to form a population of liposomes and a microdialysis region downstream from the liposome formation region and configured to form a transmembrane gradient for active drug loading of the liposomes. Microfluidic methods and systems for high throughput production of liposomes are also provided featuring high aspect ratio microchannels.

Methods for alkane dehydrogenation

Disclosed herein are methods for dehydrogenation of alkanes to olefins by co-injecting the alkane feed with hydrogen. The present methods provide the improved feed conversion, desired product selectivity, total olefins in product stream, and lower catalyst deactivation rate.

Device useful for hydrogenation reactions (ii)

The present invention relates to a device for treatment of material transported through the device comprising at least one porous element consisting of specific solid metallic structure which allows cross-flow of the material through the porous element and wherein the porous element is coated by a non-acidic metal oxide which is impregnated by palladium (Pd).

DIFFERENTIAL HYDROGENATION REACTION APPARATUS

The present disclosure provides a differential hydrogenation reaction apparatus. The apparatus comprises a mixing vessel, a plurality of microreactors and a raw material conveying device, and the mixing vessel is provided with reaction product inlets; each microreactor is used as a hydrogenation reaction place and is provided with a liquid phase reaction raw material inlet and a reaction product outlet, each reaction product outlet is connected with the corresponding reaction product inlet, the plurality of microreactors are divided into one group or a plurality of groups which are arranged in parallel, and each group comprises at least one microreactor arranged in parallel; and the raw material conveying device is arranged on a feeding pipeline of the liquid phase reaction raw material inlet. The problems of high pressure unsafety and non-equilibrium in the hydrogenation reaction process can be effectively solved by adopting the reaction apparatus. 1. A differential hydrogenation reaction apparatus , comprising:a mixing vessel with reaction product inlets;{'sup': 3', '3, 'a plurality of microreactors used as hydrogenation reaction places of a liquid phase reaction raw material, wherein each of the microreactor is provided with a liquid phase reaction raw material inlet and a reaction product outlet; the reaction product outlet is connected with the corresponding reaction product inlet; the plurality of microreactors are divided into one group or a plurality of groups which are arranged in parallel, each group comprises at least one microreactor arranged in parallel; each of the microreactor in each group of the microreactors is a pressurized microreactor with a volume smaller than or equal to 0.025 mand an inside diameter smaller than 0.1 m, or an ambient-pressure microreactor with a volume smaller than or equal to 0.1 mand an inside diameter smaller than 0.1 m; and'}a raw material conveying device, arranged on a feeding pipeline of the liquid phase reaction raw ...

High Pressure Homogenizer And Method For Manufacturing Graphene Using The Same

The present invention relates to a high pressure homogenizer and a method for manufacturing graphene using the same, and according to one aspect of the present invention, there is provided a high pressure homogenizer comprising a channel module which comprises a microchannel through which an object for homogenization passes, wherein the channel module comprises at least one baffle disposed so as to partition the microchannel into a plurality of spaces and the baffle is provided so as to partition the microchannel into two spaces along the width direction or the height direction.

Fluid flow vessel and photochemical reactor

A fluid flow-through device and a photochemical reactor. The fluid flow-through device ( 1 ) includes an outer tube ( 2 ) having an outer surface ( 21 ) and an inner surface ( 22 ); and an inner tube ( 3 ) having an outer surface ( 31 ) and an inner surface ( 32 ), the inner tube being disposed inside the outer tube and forming a channel of a fluid by the inner surface of the outer tube and the outer surface, with a distance between the inner surface of the outer tube and the outer surface of the inner tube in a thickness direction of the outer tube being from 100 nm to 5 mm. The photochemical reactor includes the fluid flow-through device and a photocatalyst disposed on at least one surface of the inner surface of the outer tube and the outer surface of the inner tube.

SYSTEM AND METHOD FOR EMULSION BREAKING AND PHASE SEPARATION BY DROPLET ADHESION

Emulsion breaking and phase separation is achieved by droplet adhesion. An emulsion breaking device includes a channel having distinct adjacent zones with distinctly different surface wettability characteristics, namely, solvophilic and solvophobic surfaces. The device is positioned such that the upstream portion of the device is configured to be wetted by the continuous phase of the emulsion, and the downstream portion of the device is configured to be wetted by the dispersed phase of the emulsion. As the emulsion flows from the upstream zone to the downstream zone, the change in surface wettability characteristics promotes adhesion of the dispersed phase as the dispersed phase wets the surface of the downstream portion of the channel, which results in breaking of the emulsion. Subsequent collection of the broken emulsion in a collection vessel results in separation of the disparate phases to facilitate their recapture and recycling. 1. A method of breaking an emulsion comprising:flowing an emulsion of droplets of a dispersed phase entrained in a continuous phase below a critical speed into one end of an emulsion breaking device comprising a body defining an elongated internal channel having an inner surface extending from a single channel inlet to a single channel outlet, a first zone of said channel having an inner surface that is solvophilic to the continuous phase, a second zone of said channel having an inner surface that is solvophobic to the continuous phase, the solvophilic and solvophobic inner surfaces meeting at a boundary intermediate a length of the channel; andcollecting liquid flowing from the emulsion breaking device.2. The method of claim 1 , wherein the collected liquid is collected in a vessel claim 1 , the method further comprising:withdrawing from the vessel one of the dispersed phase and the continuous phase separately from the other of the dispersed phase and the continuous phase.3. The method of claim 1 , wherein said flowing the emulsion ...

APPARATUS FOR MANUFACTURING QUANTUM DOT AND QUANTUM DOT MANUFACTURING METHOD USING THE SAME

An apparatus for manufacturing a quantum dot is provided, the apparatus including a first supplying part that provides a cationic precursor, a second supplying part that provides an anionic precursor, a mixing part connected to the first supplying part and the second supplying part, and a reaction part including a reaction tube configured to receive a liquid mixture of the cationic precursor and the anionic precursor from the mixing part and a first microwave generator configured to provide a microwave that is transmitted through the reaction tube. Therefore, the apparatus may produce a quantum dot of multi-element compounds. 1. An apparatus for manufacturing a quantum dot , the apparatus comprising:a first supplying part configured to provide a cationic precursor;a second supplying part configured to provide an anionic precursor;a mixing part connected to the first supplying part and the second supplying part; anda reaction part comprising a reaction tube configured to receive a liquid mixture of the cationic precursor and the anionic precursor from the mixing part and a first microwave generator configured to provide a microwave that is transmitted through the reaction tube.2. The apparatus of claim 1 , wherein the reaction tube comprises a microfluidic channel provided in a zigzag form on a plane.3. The apparatus of claim 1 , wherein the reaction tube is formed of glass claim 1 , quartz claim 1 , or Teflon.4. The apparatus of claim 1 , wherein the cationic precursor contains at least one of In claim 1 , Ga claim 1 , or Al.5. The apparatus of claim 1 , wherein the anionic precursor contains at least one of P claim 1 , As claim 1 , N claim 1 , or Sb.6. The apparatus of claim 1 , wherein the first microwave generator is disposed on at least one side of the reaction tube.7. The apparatus of claim 6 , wherein the reaction part further comprises a second microwave generator spaced apart from the first microwave generator with the reaction tube being interposed ...

FLUID INJECTION USING ACOUSTIC WAVES

The present invention generally relates to the manipulation of fluids using acoustic waves such as surface acoustic waves. In some aspects, one fluid may be introduced into another fluid via application of suitable acoustic waves. For example, a fluid may be added or injected into another fluid by applying acoustic waves where, in the absence of the acoustic waves, the fluid cannot be added or injected, e.g., due to the interface or surface tension between the fluids. Thus, for example, a fluid may be injected into a droplet of another fluid. Other embodiments of the invention are generally directed to systems and methods for making or using such systems, kits involving such systems, or the like. 1. A method , comprising:providing a microfluidic system comprising a first microfluidic channel and a second microfluidic channel contacting the first microfluidic channel at a junction;providing a droplet of the first fluid contained by a carrying fluid in the first microfluidic channel, and a second fluid in the second microfluidic channel, wherein the first fluid and the second fluid contact each other at least partially within the junction to define a fluidic interface; andapplying acoustic waves to the interface to urge the second fluid to flow into the droplet wherein, in the absence of the acoustic waves, the second fluid is not urged to enter the droplet.2. The method of claim 1 , wherein the acoustic waves are applied to at least a portion of the junction.3. The method of any one of or claim 1 , wherein the acoustic waves have an amplitude whose magnitude varies in time.4. The method of any one of - claim 1 , wherein the acoustic waves are applied to the first fluid in a direction of flow of the first fluid.5. The method of any one of - claim 1 , wherein the acoustic waves are applied to the first fluid opposite a direction of flow of the first fluid.6. The method of any one of - claim 1 , wherein the acoustic waves are applied to the second fluid in a direction ...

MICROFLUIDIC CASSETTE FOR SYNTHESIZING A RADIO-TRACER AND METHOD OF SYNTHESIZING A RADIO-TRACER WITH SUCH A CASSETTE

The present application concerns a microfluidic cassette for synthesizing a radiotracer including a microfluidic circuit in a support card that includes at least one intake for supply by a vial, at least one isotope port, at least one reaction chamber, at least one mixing chamber, at least one formulation chamber, and at least one connection for a syringe, linked together by capillaries. Also disclosed is a method for synthesizing a radiotracer in such a cassette. 1. A microfluidic cassette for synthesizing a radioactive tracer comprising:A mounting card, at least one connector for supply by a vial (Pf), configured to connect a vial (V) to the microfluidic circuit,', 'at least one isotope port (IP), configured for introducing a radioisotope into the microfluidic circuit,', {'b': 1', '2', '3', '4, 'at least one reaction chamber (R, R, R, R), connected to the at least one connector for supply by a vial and to the at least one isotope port by capillaries,'}, {'b': 1', '2', '3', '4', '1', '2', '3', '4', '1', '2', '3', '4, 'at least one mixing chamber (M, M, M, M), positioned upstream of the at least one reaction chamber (R, R, R, R) and connected to the at least one reaction chamber (R, R, R, R) upstream of which it is positioned by at least one capillary,'}, {'b': 1', '2', '3', '4, 'at least one formulation chamber (FC), connected to the at least one isotope port (IP) and to the at least one connector for supply by a vial (Pf) and positioned downstream of the at least one reaction chamber (R, R, R, R), and'}, 'at least one connector for connecting a syringe (SP), positioned downstream of the at least one formulation chamber (FC) and connected to the at least one formulation chamber by at least one capillary., 'A microfluidic circuit, at least partly integrated into the mounting card, comprising2134. The cassette according to claim 1 , wherein the at least one reaction chamber (R claim 1 , R claim 1 , R) is loaded with beads.322. The cassette according to claim 1 , ...

CATALYST SUPPORT STRUCTURE, CATALYST INCLUDING THE STRUCTURE, REACTOR INCLUDING A CATALYST, AND METHODS OF FORMING SAME

Structures, catalysts, and reactors suitable for use for a variety of applications, including gasto-liquid and coal-to-liquid processes and methods of forming the structures, catalysts, and reactors are disclosed. The catalyst material can be deposited onto an inner wall of a microtubular reactor and/or onto porous tungsten support structures using atomic layer deposition techniques. 1. A method of forming a tungsten support structure , the method comprising the steps of:providing a polymer support structure;depositing tungsten overlying the polymer support structure using atomic layer deposition; andoptionally exposing the polymer support structure to a calcination process to remove the polymer support structure and thereby form the tungsten support structure.2. The method of forming a tungsten support structure of claim 1 , wherein the tungsten is deposited directly onto the polymer support.3. The method of forming a tungsten support structure of claim 1 , further comprising the step of depositing an oxide overlying the polymer support structure claim 1 , prior to the step of depositing.4. The method of forming a tungsten support structure of claim 1 , wherein the calcination process comprises exposing the polymer support to ammonia.5. The method of forming a tungsten support structure of claim 1 , further comprising the step of:depositing one or more metals selected from the group consisting of Co, Ni, NiPt, Rh, Ru, Pd, Os, V, Fe, and Mn, using atomic layer deposition onto the tungsten support.6. The method of forming a tungsten support structure of claim 1 , wherein the method comprises the calcination process claim 1 , which comprises exposing the polymer support structure to ammonia.7. A microtubular reactor system comprising:one or more microtubes, each microtube comprising an interior wall, wherein tungsten is deposited onto the interior wall using atomic layer deposition, and wherein a metal selected from the group consisting of Co, Ni, NiPt, Rh, Ru, Pd, Os ...

Process for the preparation of N-alkyl-nitratoethylnitramines

The present invention relates to a continuous process for the preparation of N-alkyl-nitratoethylnitramines (e.g. NENA compounds, DINA). 3. The process according to claim 1 , characterised in that after the reactions the reaction mixture is brought into contact with water or an aqueous alkaline solution.4. The process according to claim 1 , characterised in that R is a methyl claim 1 , ethyl or butyl group or a group of the formula —CH—CH—O—NOand R′ is a methyl claim 1 , ethyl or butyl group or a group of the formula —CH—CH—OH.5. The process according to claim 1 , characterised in that the reactions are carried out in one or more continuous flow reactor(s).6. The process according to claim 1 , characterised in that the reactions are carried out in one or more tubular reactor(s).7. The process according to claim 1 , characterised in that the reactions are carried out in one or more microreactor(s).8. The process according to claim 1 , characterised in that the reactions are carried out at a pressure of from 0.5 bar above atmospheric pressure up to a pressure of 18 bar above atmospheric pressure.9. The process according to claim 1 , characterised in that the reaction with nitric acid is carried out at a temperature of from −20° C. to 30° C.10. The process according to claim 1 , characterised in that the reaction with a mixture of at least one acid anhydride and a chloride-containing catalyst is carried out at a temperature of from 20° C. to 60° C.11. The process according to claim 1 , characterised in that acetic anhydride is used as acid anhydride.12. The process according to claim 1 , characterised in that hydrogen chloride is used as chloride-containing catalyst.13. The process according to claim 1 , characterised in that the nitric acid used in the reaction is used with a concentration of from 75 to 96% in water.14. The process according to claim 1 , characterised in that a mixture of ethyl-NENA (R=ethyl) and methyl-NENA (R=methyl) is prepared.15. The process ...

SYSTEM AND METHOD FOR MAKING QUANTUM DOTS

Embodiments of the present disclosure provide for methods of making quantum dots (QDs) (passivated or unpassivated) using a continuous flow process, systems for making QDs using a continuous flow process, and the like. In one or more embodiments, the QDs produced using embodiments of the present disclosure can be used in solar photovoltaic cells, bio-imaging, IR emitters, or LEDs. 1. A system for making a quantum dot (QD) , comprising:a mixing device for receiving solution A and solution B, wherein the mixing device is configured to mix solution A and solution B to form solution C;a first coil in fluidic communication with the mixing device, wherein the first coil is configured to form QD seeds from solution C via nucleation; anda second coil positioned in serial communication with the first coil, wherein the second coil is in fluidic communication with the first coil, wherein the second coil is configured to grow the QDs from the QD seeds,wherein the first coil and the second coil are independent of one another.2. The system of claim 1 , wherein the system is a continuous flow process system.3. The system of claim 1 , wherein the mixing device is one or more of a mixing chip or heating column.4. The system of claim 1 , wherein one or more of solution A and solution B include a fluorinated fluid.5. The system of claim 4 , wherein the fluorinated fluid is one or more of CFN claim 4 , CHN claim 4 , FC-70 claim 4 , FC-71 claim 4 , and FC-770.6. The system of claim 1 , wherein the first coil is operated at a first temperature and the second coil is operated at a second temperature.7. The system of claim 1 , wherein the first temperature and the second temperature are different.8. The system of claim 6 , wherein the first temperature is about 110 to 130° C.9. The system of claim 6 , wherein the second temperature is about 70 to 90° C.10. The system of claim 1 , further comprising one or more containers in fluidic communication with the mixing device.11. The system of ...

Flow Synthesis of Polymer Nanoparticles

A system and method for flow synthesis of polymer nanoparticles in a continuous flow reactor having a channel. The polymer nanoparticles are synthesized from monomer in the presence of an initiator.

Inductively heated microchannel reactor

The current document is directed to an efficient multi-channel chemical reactor having a multichannel core containing a plurality of parallel channels, with conductive walls, having a varying composition along their lengths. The channels are heated by a frequency-addressing different regions within the reactor with an inductive coil, driven by an agile frequency or spread spectrum emission controller.

INTEGRATED SOLAR MICRO-REACTORS FOR HYDROGEN SYNTHESIS VIA STEAM METHANE REFORMING

A reactor for steam-methane reforming is adapted to be received in a tube on a focal axis of a parabolic trough. The reactor may comprise an array of micro-reactors interconnected by a water manifold, a gas manifold, a syngas manifold, and at least one steam-methane reforming chamber configured for reforming steam and methane into syngases, the micro-reactors having a vaporization portion for producing steam. Radiation plates may extend on sides of the array of micro-reactors Glazing may face and be spaced apart from a portion of the array of micro-reactors including at least one steam-methane reforming chamber, the glazing being conductively connected to the radiation plates for heat transfer therebetween, the at least one glazing allowing light from the parabolic trough to pass therethrough to reach the array of micro-reactors. 133.-. (canceled)34. A micro-reactor for a reforming process comprisinga cold side and a hot side opposite the cold side, the reactor configured to be supported by the cold side, the hot side configured to be exposed to a heat source;inlets defined in the cold side, the inlets configured for receiving reagents;an outlet defined in the cold side, the outlet configured for exiting reforming products;at least one reforming chamber in the hot side, the at least one reforming chamber having a catalyst, the at least one reforming chamber configured for reforming the reagents into the reforming products;a reagent path from the inlets to the at least one reforming chamber;a reforming product path from the at least one reforming chamber to the outlet; andwherein a wall is shared by the reagent path and the reforming product path for heat exchange between the reagents and the reforming products.35. The micro-reactor according to claim 34 , wherein the micro-reactor is a monolithic block.36. The micro-reactor according to claim 34 , wherein the at least one reforming chamber is a—methane reforming chamber.37. The micro-reactor according to claim 36 , ...

APPARATUS, SYSTEMS, AND METHODS FOR CONTINUOUS MANUFACTURING OF NANOMATERIALS AND HIGH PURITY CHEMICALS

A method for continuously processing at least two liquid feed streams is provided. A system for continuously processing at least two liquid feed streams is also provided. 1. A method for continuously processing at least two liquid feed streams , comprising:pumping a first feed stream to an in-line mixer at an actively automatically controlled rate;flowing a second feed stream to the in-line mixer;mixing the first and second feed streams to achieve a substantially homogeneous mixture;pumping the substantially homogeneous mixture to a high pressure pump at an actively controlled rate;pressurizing the substantially homogeneous mixture within the high pressure pump to an elevated pressure of at least 35 MPa; anddelivering the substantially homogeneous mixture to a microreactor downstream from the high pressure pump, the microreactor having a minimum channel dimension of 500 microns or less, causing the first and second liquid streams to interact within the microreactor at a nanoscale level.2. The method of claim 1 , wherein the first feed stream includes a first constituent claim 1 , and wherein the second feed stream includes a second constituent.3. The method of claim 1 , wherein the first and second feed streams are delivered to the in-line mixer in feed lines that are coaxially aligned.4. The method of claim 1 , wherein the first and second feed streams are introduced to the in-line mixer through spaced ports defined by the in-line mixer.5. The method of claim 1 , wherein the actively controlled rate for delivery of the first feed stream to the in-line mixer is effected by an actively controlled feed pump for the first feed stream.6. The method of claim 1 , further comprising cooling or quenching the substantially homogenous mixture after interaction within the microreactor.7. The method of claim 2 , wherein the first constituent includes a solvent claim 2 , and wherein the second constituent includes an antisolvent claim 2 , and wherein interaction of the solvent ...

用于液体酸烷基化反应的微通道反应器内构件模块及其装填方法

本发明属于微连续流体器件领域，公开了一种用于液体酸烷基化反应的微通道反应器内构件模块及其装填方法，内构件模块包括纤维布（1）、框架（2）、支撑筋（3）、穿钉（4）及纤维捻（5）构成。本发明将纤维布折叠均匀填充到框架之内构成纤维模块替代微通道构件，框架为内构件模块提供固定形状，支撑筋与穿钉为纤维布提供支撑，纤维捻将纤维布两端固定在框架之上。纤维模块以整砌的方式，填充到反应器外壳之内。本发明有效解决了微通道反应器加工成本高的问题，具有传热传质速率高，温度、压力及停留时间便于调控等特点。

Modular numbering-up microreactor for increasing the production of pharmaceuticals

본 발명은 의약품 생산증대를 위한 모듈 조립형 넘버링업 금속 마이크로반응기에 관한 것이다. 구체적으로 원료주입 및 혼합모듈, 유량분배모듈, 촉매반응모듈, 통합배출모듈을 조립하여 구성된 넘버링업 마이크로반응기 및 이를 이용하여 의약품 또는 의약품 원료 화합물을 생산하는 방법에 관한 것으로, 더욱 상세하게는 합성대상으로 따라 촉매모듈의 교환이 가능한 다용도 마이크로반응기와 이를 이용한 각종 의약품 또는 의약품 원료 화합물의 스케일-업 생산 방법에 관한 것이다. The present invention relates to a modular numbering-up metal microreactor for increasing pharmaceutical production. Specifically, it relates to a numbering-up microreactor constructed by assembling a raw material injection and mixing module, a flow distribution module, a catalytic reaction module, and an integrated discharge module, and a method of producing pharmaceuticals or pharmaceutical raw material compounds using the same. The present invention relates to a multi-purpose microreactor capable of exchanging catalyst modules and a scale-up production method of various pharmaceuticals or pharmaceutical raw material compounds using the same.

制备基于c3-c8单烯属不饱和单-或二羧酸或其酸酐和盐的高度支化聚合物的连续方法

本发明涉及一种借助C 3 -C 8 烯属不饱和单-或二羧酸及其酸酐和盐(单体A)和任选水溶性单烯属不饱和共聚单体(单体B)在含水介质中在至少一种水溶性引发剂存在下的自由基聚合制备单体A的高度支化均聚物或共聚物的连续方法，其中该聚合在至少一个管式反应器节段中进行。

Device useful for hydrogenation reactions(ii)

본 발명은, 수송된 물질을 하나 이상의 다공성 부재를 포함하는 장치를 통해 처리하는 장치에 관한 것이며, 이때 상기 다공성 부재는, 상기 다공성 부재를 통한 물질의 교차-흐름을 허용하는 특정 고체 금속 구조물로 이루어지고, 상기 다공성 부재는, 팔라듐(Pd)으로 함침된 비-산성 금속 산화물로 코팅된다. The present invention relates to an apparatus for treating a transported material through a device comprising at least one porous member, wherein the porous member consists of a specific solid metal structure that allows cross-flow of the material through the porous member. The porous member is coated with a non-acidic metal oxide impregnated with palladium (Pd).

Microchannel reactor internal component module for liquid acid alkylation reaction and filling method of microchannel reactor internal component module

本发明属于微连续流体器件领域，公开了一种用于液体酸烷基化反应的微通道反应器内构件模块及其装填方法，内构件模块包括纤维布（1）、框架（2）、支撑筋（3）、穿钉（4）及纤维捻（5）构成。本发明将纤维布折叠均匀填充到框架之内构成纤维模块替代微通道构件，框架为内构件模块提供固定形状，支撑筋与穿钉为纤维布提供支撑，纤维捻将纤维布两端固定在框架之上。纤维模块以整砌的方式，填充到反应器外壳之内。本发明有效解决了微通道反应器加工成本高的问题，具有传热传质速率高，温度、压力及停留时间便于调控等特点。

Microreactor

Process-intensified flow reactor

A flow reactor has a module having a process fluid passage with an interior surface, a portion of the passage including a cross section along the portion having a cross-sectional shape, and a cross-sectional area with multiple minima along the passage. The cross-sectional shape varies continually along the portion and the interior surface of the portion includes either no pairs of opposing flat parallel sides or only pairs of opposing flat parallel sides which extend for a length of no more than 4 times a distance between said opposing flat parallel sides along the portion and the portion contains a plurality of obstacles distributed along the portion.

Improved process intensified flow reactor

本申请涉及改进的工艺强化流反应器。流反应器具有模块，所述模块具有加工流体通道，所述加工流体通道具有内表面，通道的一部分包括：沿着该部分的横截面，所述横截面具有横截面形状，以及沿着通道具有多个最小值的横截面面积。横截面形状沿着该部分连续变化，并且该部分的内表面不包括相对的平坦平行侧面对或者仅包括如下相对的平坦平行侧面对，其延伸的长度不超过沿着该部分的所述相对的平坦平行侧面之间的距离的4倍，以及该部分含有沿着该部分分布的多个障碍物。

Differential hydrogenation reaction device

本发明提供了一种微分式加氢反应装置。该装置包括混合容器、多个微型反应器、原料输送装置，混合容器设置有反应产物进口；微型反应器用于作为加氢反应场所；微型反应器具有液相反应原料进口和反应产物出口，反应产物出口与反应产物进口相连，多个微型反应器分成并联设置的一组或多组，每组中包括至少一个并联设置的微型反应器；且每组中的各微型反应器均为容积≤0.025m 3 、内径＜0.1m的带压微型反应器或者均为容积≤0.1m 3 、内径＜0.1m的常压微型反应器；原料输送装置设置在液相反应原料进口的进料管路上，用于将液相反应原料输送至微型反应器中。采用该反应装置能够有效解决目前加氢反应过程中的高压不安全和非均衡性问题。

Flow reactor synthesis of polymers

本发明的名称为聚合物的流动反应器合成。流动反应器系统和方法，其具有用作聚合室的管。流动反应器具有至少一个入口和至少一个混合室，和出口。方法包括提供两相，水相和非水相，和形成用于引入至流动反应器的乳液。

Inductively heated microchannel reactor

【課題】誘導加熱されるマイクロチャネル反応器を提供すること。【解決手段】本開示は、長さに沿って変化する組成を有する導電性壁を備える複数の平行チャネルを含むマルチチャネルコアを有する効率的なマルチチャネル化学反応器に向けられる。チャネルは、アジャイル周波数またはスペクトラム拡散放出コントローラによって駆動される誘導コイルを備える反応器内の周波数アドレッシングの異なる領域によって加熱される。【選択図】図１

Microfluidic droplet packing

Systems and methods for confining droplets within a microfluidic channel as well as systems and methods for packing droplets are provided. More specifically, a system and method are provided for controlling the introduction and removal of oil into a microfluidic channel in order to control where drops are allowed to flow within that channel.

Methods of using microfluidic positional encoding devices

The invention relates to methods and compositions useful for routing and tracking multiple mobile units within a microfluidic device. Mobile units may be routed through a plurality of chemical environments, and the mobile units may be tracked to determine the path and/or environments that the mobile units have routed through. Mobile units may be routed in accordance with a predetermined algorithm. Mobile units may be routed through microfluidic devices in ordered flow. Mobile units routed through the microfluidic device can be used to perform various chemical reactions uniquely associated to the units, including without limitation peptide synthesis, enzymatic gene synthesis and gene assembly.

Microfluidic droplet packing

Systems and methods for producing a chemical product

The invention generally provides systems and methods for producing a chemical product. In certain embodiments, the invention provides systems that include a chemical product production unit. The chemical production unit includes a plurality of microfluidic modules configured to be fluidically coupled to each other in an arrangement that produces a chemical product from an input of a plurality of starting reagents that react with each other due to conditions within the plurality of microfluidic modules through which the starting reagents flow. The system also includes a droplet dispenser fluidically coupled to the chemical product production unit that forms and dispenses droplets of the chemical product.

Method for preparing core-shell type microspheres and coaxial microfluid device applied to method

本发明涉及生物、药学、材料制备领域，尤其是药物载体领域，具体为一种制备核壳型微球的方法，以及应用该方法的共轴微流体装置。本发明的方案利用了油水的剪切作用以及表面活性剂的双重作用，制备了一种稳定的核壳型乳液，然后利用光交联的方式，将乳液中的核分离出来，形成均匀的核壳球体，可以应用在药物缓释方面。

Multi-functional compact fuel converter and a process for converting liquid fuel

A compact multi-functional fuel converter and a process for converting liquid fuel to a product, which includes providing a supply of oxygen gas, providing a supply of liquid fuel, electrically atomizing the fuel, evaporating the fuel and catalytically reacting the liquid fuel and oxygen in the reactor.

Fluid flow vessel and photochemical reactor

本発明によれば、流体の流量が大きく、製造コストが低く、メンテナンスが容易である流体流通器および光化学反応器を提供する。本発明の流体流通器１は、外面２１および内面２２を有する外管２と、外面３１および内面３２を有し、外管２の内側に配置され、外管２の内面２２および外面３１で流体の流路を形成する内管３とを含み、外管２の肉厚方向における外管２の内面２２と内管３の外面３１との間の距離が１００ｎｍ～５ｍｍである。本発明の光化学反応器は、本発明の流体流通器１と、外管２の内面２２および内管３の外面３１の少なくとも一方の面に配置された光触媒とを含む。

Micro-reaction system for preparing nano-drugs and application thereof

本发明公开了一种制备纳米药物的微反应系统及其应用，包括流体驱动单元、混合重结晶单元、以及样品干燥收集单元；流体驱动单元包括一组动力泵，其出液口分别连接至混合重结晶单元进液口；混合重结晶单元包括混合结晶模块、温控模块、光谱监测模块和高速相机模块；混合结晶模块为一具有多个重复单元的微混合通道；温控模块接触地设置在混合结晶模块外部；高速相机模块位于混合结晶模块一侧；微混合通道的重复单元之间，通过一组并联管道与光谱监测模块连接；样品干燥收集单元与混合重结晶单元的末端出液口连接，用于将符合粒径要求的药物喷入干燥收集单元内进行干燥，并收集得到干燥好的粉末状纳米药物。

Apparatus for the production of a radiopharmaceutical comprising a piercing device

The present invention provides a system for the production of a radiopharmaceutical including a radiosynthesis apparatus and a disposable cassette. The system of the invention includes a device that enables a position on the cassette to be freed for inclusion of an additional reagent vial. With the system of the invention a broader range of radiochemical syntheses can be envisaged using the cassette.

Enhanced microchannel or mesochannel device and additive manufacturing method thereof

化学处理器被构造来减轻质量、与太阳能聚集器结合工作和/或将多孔插入物容纳在通过增材制造制成的微通道或中通道装置中。还公开通过增材制造来制作包含多孔插入物的化学处理器的方法。

Micro reactor.

Un micro-reactor (100) se provee con: un pasaje o canal (110) de flujo de reacción en el cual circula un fluido como un objeto de reacción; y un canal (120) de flujo de medio, el cual se provee paralelo al canal (110) de flujo de reacción, y en el cual circula un medio de calor que intercambia calor con el fluido en el canal (110) de flujo de reacción. El área transversal del canal (120) del flujo del medio adyacente a una porción del canal (110) del flujo de reacción que tiene una generación de calor o absorción de calor relativamente grande debido a que la reacción del fluido es menor que el área transversal de la porción del canal (110) del flujo del medio adyacente a una porción del canal (110) del flujo de reacción que tiene una generación de calor o absorción de calor relativamente menor debido a la reacción del fluido.

Device and method for testing catalysts with variable process pressure adjustment

The present invention relates to a catalysis apparatus for testing catalysts with variable process pressure adjustment over a pressure range from 0.01 millibar to 300 bar. The apparatus preferably has a plurality of reaction chambers ( 101, 102 , . . . ) arranged in parallel, the reaction chamber outlet-side lines ( 211, 212 , . . . ) of which are divided into two groups of sub-lines. One group of main lines ( 411, 412 , . . . ) is operatively connected to a regulating valve ( 61 ), which is common to all of the main lines, and to an exhaust-air line ( 62 ), and the second group of secondary lines ( 311, 312, 313 , . . . ) and switching valves ( 321, 322 , . . . ) is operatively connected to an analysis unit ( 34 ). It is preferable for reaction chamber outlet-side lines ( 201, 202 , . . . ) to be equipped in each case with a separate line for regulating fluid supply ( 211, 212 , . . . ). In a preferred embodiment, the connecting points of the reaction chamber outlet-side lines ( 201, 202 , . . . ) to the respective main lines ( 411, 412 , . . . ) and secondary lines ( 311, 312 , . . . ) have in each case one mixing vessel ( 301, 302 , . . . ).

Block-hole type silicon carbide microreactor and use thereof

The present application relates to a block-hole type silicon carbide microreactor and use thereof, which relate to the field of chemical heat exchange. The block-hole type silicon carbide microreactor comprises a matrix block and a sealing plate, wherein the matrix block is provided with at least one material guide channel for input and output of a fluid medium and at least one heat exchange channel for input and output of a heat exchange medium; a plurality of sets of through holes are provided in the sealing plate, and the sealing plate is fixed to the matrix block in a sealed manner, such that the through holes are in communication with the material guide channel, or with both the material guide channel and the heat exchange channel; and the block-hole type silicon carbide microreactor is used for mixing and/or heat exchange of the fluid medium. The present application has the effect of ensuring that the silicon carbide microreactor maintains high throughput under a high temperature and high pressure environment.

Apparatus, systems, and methods for continuous manufacturing of nanomaterials and high purity chemicals

High pressure homogenizer and manufacturing method for Graphene using the same

본 발명은 고압 균질화 장치 및 이를 이용한 그래핀의 제조방법에 관한 것으로, 본 발명의 일 측면에 따르면, 균질화를 위한 대상물이 통과하는 마이크로 채널을 포함하는 채널 모듈을 포함하며, 마이크로 채널에는 대상물이 통과하는 방향을 따라 제1 유로 및 제2 유로가 차례로 마련되고, 제1 유로에는 마이크로 채널을 복수 개의 공간으로 구획하도록 배치된 복수 개의 제1 배플이 마련되며, 제2 유로에는 마이크로 채널을 복수 개의 공간으로 구획하도록 배치된 복수 개의 제2 배플이 마련되고, 적어도 하나의 제1 배플은 인접하는 2개의 제2 배플 사이에 위치하도록 마련된 고압 균질화 장치가 제공된다. The present invention relates to a high pressure homogenization device and a method of manufacturing graphene using the same, according to an aspect of the present invention, includes a channel module including a micro channel through which an object for homogenization passes, and an object through the micro channel A first flow path and a second flow path are sequentially provided along a direction in which the first flow path is provided, and a plurality of first baffles are arranged to divide the micro-channel into a plurality of spaces, and the second flow path is provided with a plurality of micro-channel spaces. A plurality of second baffles arranged to be partitioned is provided, and at least one first baffle is provided with a high pressure homogenization device provided to be positioned between two adjacent second baffles.

Systems, methods, and apparatuses for fischer-tropsch reactor cascade

Methods, systems and apparatuses are disclosed for a Fischer-Tropsch ("FT") operation including a first FT stage comprising at least one FT reactor having a first FT catalyst and a first heat transfer surface area to catalyst volume configured to receive a first feed comprising synthesis gas and to convert a first portion of the synthesis gas in the first feed into first FT products. The disclosure also provides for a separation apparatus configured to separate the first FT products into first liquid FT hydrocarbons and first FT tail gas comprising unreacted syngas and for a second FT stage comprising at least one second FT reactor, having a second FT catalyst and a second heat transfer surface area to catalyst volume different from the first heat transfer surface area to catalyst volume, and configured to receive a second feed comprising the first FT tail gas and to convert at least a portion of the second feed into a second FT products.

It is converted and is modified using the heavy fossil hydrocarbon of radio frequency or microwave energy

可以使用微波(MW)和/或射频(RF)能量增强重化石烃(HFH)向多种增值的化学品和/或燃料的转化。反应物、过程参数、和反应器设计的变化可显著影响作为产物产生的化学品和燃料的相对分布。在一个实例中，用于HFH的瞬时微波转化的系统包括：将微波或RF能量聚集到具有大于0.9atm压力的反应区中的源，通过所述反应区的具有HFH和工艺气体的连续进料，至少在所述反应区中接触HFH的HFH‑至‑液体催化剂，和所述反应区内的电介质放电。所述HFH和所述催化剂具有小于30秒的在所述反应区中的停留时间。在一些情况下，等离子体可以在所述反应区之中或附近形成。

System and method for emulsion breaking and phase separation by droplet adhesion

Emulsion breaking and phase separation is achieved by droplet adhesion. An emulsion breaking device includes a channel having distinct adjacent zones with distinctly different surface wettability characteristics, namely, solvophilic and solvophobic surfaces. The device is positioned such that the upstream portion of the device is configured to be wetted by the continuous phase of the emulsion, and the downstream portion of the device is configured to be wetted by the dispersed phase of the emulsion. As the emulsion flows from the upstream zone to the downstream zone, the change in surface wettability characteristics promotes adhesion of the dispersed phase as the dispersed phase wets the surface of the downstream portion of the channel, which results in breaking of the emulsion. Subsequent collection of the broken emulsion in a collection vessel results in separation of the disparate phases to facilitate their recapture and recycling.

Methods of using microfluidic positional encoding devices

The invention relates to methods and compositions useful for routing and tracking multiple mobile units within a microfluidic device. Mobile units may be routed through a plurality of chemical environments, and the mobile units may be tracked to determine the path and/or environments that the mobile units have routed through. Mobile units may be routed in accordance with a predetermined algorithm. Mobile units may be routed through microfluidic devices in ordered flow. Mobile units routed through the microfluidic device can be used to perform various chemical reactions uniquely associated to the units, including without limitation peptide synthesis, enzymatic gene synthesis and gene assembly.

Fluidic devices with reaction wells and constriction channels and uses thereof

For the production of the method for amino alcohol

本发明涉及用于生产APD和N-烷基-APD的方法，其中1-CPD与水性铵或水性烷基胺在碱性条件下反应并且在此情况下在包括其中建立了至少两个反应区的管式反应器的反应器中以连续模式实施该方法。

Flow reactor synthesis of polymers

A flow reactor system and methods having tubing useful as polymerization chamber. The flow reactor has at least one inlet and at least one mixing chamber, and an outlet. The method includes providing two phases, an aqueous phase and a non-aqueous phase and forming an emulsion for introduction into the flow reactor.

Micro reactor

　マイクロリアクタ（１００）は、反応対象としての流体を流通させる反応流路（１１０）と、反応流路（１１０）と並行して設けられ、反応流路（１１０）中の流体と熱交換する熱媒体を流通させる媒体流路（１２０）とを備える。反応流路（１１０）のうち、流体の反応に伴う発熱または吸熱が相対的に大きい部分に隣接する媒体流路（１２０）の断面積は、反応流路（１１０）のうち、流体の前記反応に伴う発熱または吸熱が相対的に小さい部分に隣接する媒体流路（１２０）の断面積より小さい。

Method for the continuous production of biomethanol diesel

Synthesis method and synthesis reactor of high-selectivity 2-methylallyl chloride

本发明涉及一种高选择性2‑甲基烯丙基氯的合成方法及合成反应器，是以异丁烯和氯气为原料，在有冷却面的微通道反应器中进行气相氯化反应得到。异丁烯和氯气在T字型微通道反应器中进行反应，其混合速度极快，同时，巨大的单位反应体积换热面积可保证反应在基本恒定的温度下稳定进行，可控性好；因此可有效抑制因局部温度过高引起的副反应，反应选择性高，不会产生结焦现象。

Fluidic devices with reaction wells and constriction channels and uses thereof

The present disclosure provides fluidic devices and fluidic device assemblies, including microfluidic devices and cartridges comprising the same, that in illustrative embodiments, can be used to make particles or protein precipitates, or to monitor precipitate formation. The fluidic devices typically include channels that connect a reaction well to an inlet port and an outlet port, and a fluidic constriction channel that is configured to help retain fluids in the reaction well and/or promote mixing within the reaction well. In some aspect, fluidic devices are interconnected into fluidic assemblies that can be used in continuous process methods.

Conversion of methane to ethylene comprising integration with the in-situ ethane cracking and direct conversion of co2 byproduct to methanol

Methods and catalysts for producing ethylene and methanol from natural gas are presented. Methods include integration of oxidative conversion of methane to ethane, ethane in situ thermal cracking using the thermal heat generated thereby and direct hydrogenation of byproducts to methanol or oxidative CO2 autothermal reforming of methane to syngas.

Triphasic flow millireactors

Disclosed is a reactor system that contains multiple millireactors, each including a millitube, a first feed line, a second feed line, and a third feed line. Each of the first and second feed lines has a hydraulic damper disposed therein. Also disclosed is a process for conducting in a millitube a triphasic flow reaction that requires a liquid reactant, a gas reactant, and a catalyst.

A kind of continuous stream synthesis technique of phenylhydrazine salt and substituted benzene hydrazonium salt

本发明提供一种苯肼盐及取代苯肼盐的连续流合成工艺，创新性地将重氮化、还原和酸解成盐三步反应有机地整合在一起，以苯胺或取代苯胺酸性料液、重氮化试剂、还原剂和酸为原料，连续依次经重氮化、还原和酸解成盐三步反应得到苯肼衍生物的盐，所述的合成工艺在一个一体化反应器中进行，是一种集成式的解决方案。在所述一体化反应器的进料口不间断加入反应原料，在一体化反应器中连续依次进行重氮化、还原和酸解成盐反应，在所述一体化反应器出料口不间断得到苯肼衍生物的盐，反应总时间≤20min。与传统的生产工艺相比，反应总时间大大缩短，安全性大幅度提高，而且反应过程和反应产物中均不包含反应副产物（例如，重氮氨基化合物、还原反应中间体），所述的连续流工艺不包含额外的纯化步骤，就可制得纯度高达99%以上的高纯度产品。

Device useful for hydrogenation reactions(ii)

본 발명은, 다공성 부재를 통한 물질의 교차-흐름을 허용하는, 특정 고체 금속 구조물로 이루어진 하나 이상의 다공성 부재를 포함하는, 장치를 통해 수송된 물질을 처리하는 장치로서, 상기 다공성 부재가, 팔라듐(Pd)으로 함침된 비-산성 금속 산화물로 코팅된, 장치에 관한 것이다.

Equipment for the manufacture of radiopharmaceuticals with perforation devices

Continuous process for the production of trazodone base

The equipment for producing radiopharmaceutical including lancing device

本发明提供一种用于生产放射性药物的系统，其包括放射合成设备和一次性盒。本发明的系统包括允许释放盒上的位置以包括额外的反应剂小瓶的装置。利用本发明的系统，使用盒可设想较宽范围的放射化学合成。

Continuous synthesus of n-alkyl-nitratoethylnitramines at elevated pressures

Provided herein is a process for the continuous synthesis of N-alkyl nitratoethylnitramines. The process may comprise the preparation of a compound of the formula (I): or of mixtures of two or more such compounds, where R is an alkyl group having from 1 to 6 carbon atoms or a group of the formula -CH2-CH2-0-NO2. The process may also comprise the reaction of a compound of the formula (II), or of two or more of such compounds:

Method for preparing Invokana medicine intermediate by using micro-reactor

本发明公开了一种利用微反应器制备列净类药物中间体的方法，将溶于有机溶剂的化合物III与有机金属试剂分别通过物料通道在微反应器单元(L)内混合，并经(L)流向微反应器单元(H)；溶于有机溶剂的化合物II通过物料通道与上述混合液在预设温度为(T2)的微反应器单元(H)中混合，并通过该微反应器单元(H)，待反应完毕后从出口流出，对该流出的反应液进行后处理，即得目标化合物--列净类药物中间体I。本发明利用微反应器合成中间体(I)，可以有效解决此类反应的传热问题，由于微反应器中反应物的混合极其充分，从而缩短的反应时间，提高了反应效率，微反应器几乎没有放大效应，同时具有较高的安全性能，适合工业化生产。

Flow reactor synthesis of polymers

A flow reactor system and methods having tubing useful as polymerization chamber. The flow reactor has at least one inlet and at least one mixing chamber, and an outlet. The method includes providing two phases, an aqueous phase and a non-aqueous phase and forming an emulsion for introduction into the flow reactor.

Reactor and reactor system with the same

Apparatus, systems, and methods for continuous manufacturing of nanomaterials and high purity chemicals

continuous process for the manufacture of mono- or di-carboxylic acid homo- or copolymers, polymer obtainable by the continuous process, and use of a polymer

1 / 1 resumo “processo contãnuo para a fabricaã‡ãƒo de homo- ou copolãmeros de ãcido mono- ou di-carboxãlico, polãmero obtenãvel pelo processo contãnuo, e, uso de um polãmero” a presente invenã§ã£o refere-se a um processo contã­nuo para a fabricaã§ã£o de homo- ou copolã­meros altamente ramificados de ã¡cido mono- ou di-carboxã­lico c -c monoetilenicamente insaturado, bem como os 3 8 anidridos e os sais dos mesmos (monã´mero a) por meio de polimerizaã§ã£o de radicais livres de monã´mero a e opcionalmente comonã´meros solãºveis em ã¡gua monoetilenicamente insaturados (monã´mero b) em um meio aquoso na presenã§a de pelo menos um iniciador solãºvel em ã¡gua, em que a polimerizaã§ã£o ocorre em pelo menos um segmento do reator tubular. 1 / 1 abstract “continuous process for the manufacture of mono- or di-carboxylic acid homo- or copolymers, a polymer obtainable by the continuous process, and, use of a polymer - the present invention relates to a continuous process for the manufacture of homo- or highly branched copolymers of mono- or di-carboxylic acid c- c monoethylenically unsaturated, as well as the 38 anhydrides and salts thereof (monomer a) via free radical polymerization of monomer a and optionally water-soluble monomers monoethylenically unsaturated (mono mer b) in an aqueous medium in the presence of at least one water-soluble initiator, wherein polymerization takes place in at least one segment of the tubular reactor.

System and method for making quantum dots

Embodiments of the present disclosure provide for methods of making quantum dots (QDs) (passivated or unpassivated) using a continuous flow process, systems for making QDs using a continuous flow process, and the like. In one or more embodiments, the QDs produced using embodiments of the present disclosure can be used in solar photovoltaic cells, bio-imaging, IR emitters, or LEDs.

Modular systems for performing multistep chemical reactions, and methods of using same

Disclosed are modular chemical reaction systems and methods of using such chemical reaction systems. The disclosed systems can have a substrate layer and a plurality of modules selectively mounted to an outer surface of the substrate layer. The substrate layer can include flow connectors that cooperate with the modules to form a fluid flow pathway for performing at least one step of a chemical reaction. At least one of the modules can be a process module, such as a reactor or separator. The modules can also include at least one regulator module. The system can also include at least one analysis device that analyzes at least one characteristic of the chemical reaction as the reaction occurs. The system can also include processing circuitry that monitors and/or optimizes the chemical reaction based on feedback received from the analysis device or other system components.

Methods of generating microparticles and porous hydrogels using microfluidics

Provided herein are methods utilizing microfluidics for the oxygen-controlled generation of microparticles and hydrogels having controlled microparticle sizes and size distributions and products from provided methods. The included methods provide the generation of microparticles by polymerizing an aqueous solution dispersed in a non-aqueous continuous phase in an oxygen-controlled environment. The process allows for control of size of the size of the aqueous droplets and, thus, control of the size of the generated microparticles which may be used in biological applications.

Polymerization reactions within microfluidic devices

The present invention generally relates to polymerization reactions within microfluidic devices. In certain cases, the invention allows for precise control of the polymerization of different types of monomers to form a copolymer by controlling the steps of polymerization and/or controlling the addition of monomers at various time scales within a microfluidic droplet and/or a microfluidic environment, often to a degree that is unattainable by other block polymerization techniques. For example, in one aspect, the present invention is directed to systems and methods for producing polymers such as block copolymers, gradient polymers, random copolymers, etc. For instance, in one set of embodiments, a first monomer contained within a channel, such as a microfluidic channel, is allowed to polymerize to form a first block of a block copolymer. Additional blocks may be added, for example, by flowing the first block and other monomers through a second channel (which may be an extension of the first channel), by polymerizing additional blocks of the copolymer in other channels, by creating droplets containing one or more blocks and allowing the blocks to polymerize, or the like. In some embodiments, a droplet, such as a multiple emulsion droplet, may be creating containing two or more monomers, which are allowed to polymerize together. Still other embodiments of the invention are generally directed to methods of creating such devices, methods of using such devices, kits involving such devices, or the like.

Integral microchannels reaction unit and the method for preparing two-(2- chloroethyl) di-phosphate esters using the device

本发明公开了一体式微通道反应装置及利用该装置制备二‑（2‑氯乙基）磷酸二酯的方法，其由5~9级相互串联的微通道反应器串联而成，其中一级为预热段，其余为重排反应段；每级微通道反应器包括若干环形管路，所述环形管路包括内径管和外径管，所述外径管套设在内径管外周，所述环形管路为内径管和外径管之间构成环形空间。本发明采用环形微通道，具有物料料层薄，传质传热效率好，温度稳定好，高效低耗能的特点。

Gas driven fluid transport

Fluid transport approaches are described that operate without the need for precise displacement of an actuator and with little or no sensing in the flow path. In certain implementations, a gas phase in a fluid reservoir is compressed by a pressure source such that releasing the pressure, such as by opening a valve to an intermediary conduit, displaces fluid to the intermediary chamber. Closing that fluid path and opening a different fluid path to a chamber at ambient temperature causes the fluid to be displaced to the chamber.

Microfluidic cassette for synthesizing a radio-tracer and method of synthesizing a radio-tracer with such a cassette

The present application concerns a microfluidic cassette for synthesizing a radiotracer including a microfluidic circuit in a support card that includes at least one intake for supply by a vial, at least one isotope port, at least one reaction chamber, at least one mixing chamber, at least one formulation chamber, and at least one connection for a syringe, linked together by capillaries. Also disclosed is a method for synthesizing a radiotracer in such a cassette.

Microfluidic Cassettes for Synthesizing Radiotracers and Methods of Synthesizing Radiotracers in Such Cassettes

Heavy fossil hydrocarbon conversion and upgrading using radio-frequency or microwave energy

Conversion of heavy fossil hydrocarbons (HFH) to a variety of value-added chemicals and/or fuels can be enhanced using microwave (MW) and/or radio-frequency (RF) energy. Variations of reactants, process parameters, and reactor design can significantly influence the relative distribution of chemicals and fuels generated as the product. In one example, a system for flash microwave conversion of HFH includes a source concentrating microwave or RF energy in a reaction zone having a pressure greater than 0.9 atm, a continuous feed having HFH and a process gas passing through the reaction zone, a HFH-to-liquids catalyst contacting the HFH in at least the reaction zone, and dielectric discharges within the reaction zone. The HFH and the catalyst have a residence time in the reaction zone of less than 30 seconds. In some instances, a plasma can form in or near the reaction zone.