КАТАЛИЗАТОРЫ ГИДРООЧИСТКИ НА ПОДЛОЖКАХ, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ АКТИВНОСТЬЮ

В данном изобретении предложены катализаторы на подложке, способ его получения, а также способ гидроочистки, гидродеазотирования и/или гидродесульфуризации с применением катализаторов на подложках. Катализатор на подложке содержит носитель, фосфор, по меньшей мере один металл группы VIB, по меньшей мере один металл группы VIII и полимер, причем данный полимер содержится в катализаторе в количестве около 1,5 мас.% или более относительно общей массы других компонентов в катализаторе. Молярное соотношение между фосфором и металлом группы VIB составляет от около 1:1,5 до менее чем около 1:12. Молярное соотношение между металлом группы VIB и металлом группы VIII составляет от около 1:1 до около 5:1. Полимер имеет углеродный скелет (основную цепь) и содержит функциональные группы, содержащие по меньшей мере один гетероатом. Способ получения катализатора на подложке включает: I) соединение вместе компонентов в любой из следующих комбинаций: a-i) носитель, один или более мономерных компонентов, ...

КАТАЛИЗАТОР НА НОСИТЕЛЕ, ЕГО АКТИВИРОВАННАЯ ФОРМА И ИХ ПОЛУЧЕНИЕ И ПРИМЕНЕНИЕ

... 1. Катализатор на носителе, содержащий: органический полимерный материал-носитель и частицы сплава Ренея, поддерживаемые на органическом полимерном материале-носителе, где по существу все частицы сплава Ренея являются частично заделанными в органический полимерный материал-носитель.2. Катализатор по п. 1, где этот сплав Ренея содержит по меньшей мере один металл Ренея и по меньшей мере один способный выщелачиваться элемент.3. Катализатор по п. 2, где по меньшей мере один металл Ренея выбран из никеля, кобальта, меди и железа, и по меньшей мере один способный выщелачиваться элемент выбран из алюминия, цинка и кремния.4. Катализатор по п. 2, где массовое отношение металла Ренея к способному выщелачиваться элементу в сплаве Ренея составляет от 1:99 до 10:1.5. Катализатор по п. 4, где массовое отношение металла Ренея к способному выщелачиваться элементу в сплаве Ренея составляет от 1:10 до 4:1.6. Катализатор по п. 2, где сплав Ренея дополнительно содержит по меньшей мере один промотор, выбранный ...

CYCLOOLEFINKOMPLEXE OF PLATINUM, PROCEDURE FOR THEIR PRODUCTION AS WELL AS THEIR USE AS CATALYST.

TRANSITION METAL CATALYSTS FOR HYDROGENATION AND HYDROSILYLATION

Phosphoranimide-metal catalysts and their role in hydrogenation and hydrosilylation are disclosed. The catalysts comprise first row transition metals such as nickel, cobalt or iron. The catalysts have a metal to anionic phosphoranimide ratio of 1:1. This disclosure presents a process for catalytic hydrogenation and hydrosilylation of a range of unsaturated organic compounds under lower temperature and pressure conditions than conditions associated with industrial hydrogenation and hydrosilylation.

SUPPORTED HYDROTREATING CATALYSTS HAVING ENHANCED ACTIVITY

This invention provides supported catalysts comprising a carrier, phosphorus, at least one Group VI metal, at least one Group VIII metal, and a polymer. In the catalyst, the molar ratio of phosphorus to Group VI metal is about 1:1.5 to less than about 1:12, the molar ratio of the Group VI metal to the Group VIII metal is about 1:1 to about 5:1, and the polymer has a carbon backbone and comprises functional groups having at least one heteroatom. Also provided are a process for preparing such supported catalysts, as well as methods for hydrotreating, hydrodenitrogenation, and/or hydro desulfurization, using supported catalysts.

ENANTIOSELECTIVE OXAZABOROLIDINE CATALYSTS

Verfahren zur Amalgam-Hydrodimerisation von ungesättigten Verbindungen

CATALYST COMPOSITION POLYMERIZATION OF OLEFINS

hidrogenação homogênea de ésteres utilizando um complexo de ferro como catalisador

supported hydrotreating catalysts having enhanced activity, method of hydrotreating and layering process supported catalyst

Chiral metal complex compounds

The invention comprises novel chiral metal complex compounds of the formulawherein M, PR2, R3 and R4 are outlined in the description, its stereoisomers, in the form as a neutral complex or a complex cation with a suitable counter ion. The chiral metal complex compounds can be used in asymmetric reactions, particularly in asymmetric reductions of ketones, imines or oximes.

КАТАЛИЗАТОРЫ ГИДРООЧИСТКИ НА ПОДЛОЖКАХ, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ АКТИВНОСТЬЮ

... 1. Катализатор на подложке, содержащий носитель, фосфор, по меньшей мере один металл группы VIB, по меньшей мере один металл группы VIII и полимер, при этоммолярное соотношение между фосфором и металлом группы VIB составляет от около 1:1,5 до менее чем около 1:12,молярное соотношение между металлом группы VIB и металлом группы VIII составляет от около 1:1 до около 5:1, иполимер имеет углеродный скелет и содержит функциональные группы, содержащие по меньшей мере один гетероатом.2. Катализатор по п. 1, отличающийся тем, что указанный носитель представляет собой оксид кремния, оксид алюминия, оксид кремния-оксид алюминия, оксид алюминия с диспергированным в нем оксидом кремния-оксидом алюминия, покрытый оксидом алюминия оксид кремния или покрытый оксидом кремния оксид алюминия, и/или отличающийся тем, что функциональные группы полимера представляют собой группы карбоновой кислоты.3. Катализатор по п. 1, отличающийся тем, что молярное соотношение между фосфором и металлом группы VIB составляет ...

A supported catalyst, its activated form, and their preparation and use

REDUCTION OF CARBONYLVERBINDUNGEN BY A SILANE DERIVATIVE IN PRESENCE A ZINC CATALYST

4-CYKLOHEXYL-1,3,2-OXAZABOROLIDINE AS CHIRALE AID

Divalent lanthanide reduction catalysts

Enantioselective oxazaborolidine catalysts

The enantioselective borane reduction of prochiral ketones to optically pure alcohols is effectively achieved by performing the reduction in the presence of catalytic amounts of the new and valuable oxazaborolidine compounds of formulae (I) and (II). The compounds of formulae (I) and (II) may be isolated and purified prior to use in the reduction reactions or the compounds of formulae (I) and (II) may be generated in situ.

NAPHTHENIC HYDROCARBON ADDITIVES FOR DIARYL PHOSPHIDE SALT FORMATION

The invention relates to the use of polycyclic aromatic hydrocarbons (PAHs) such as naphthalene and its alkyl, aryl, or heteroatom substituted analogs, that act as catalysts in the presence of an alkali metal (Li, K, Na) for the reduction of electron-deficient and electron-rich triaryl phosphines to their corresponding alkali metal diaryl phosphide salts. The process is also useful for the catalysis of triaryl phosphine chalcogen adducts such as the sulfides, oxides, and selenides, diaryl(halo)phosphines, triaryl phosphine-borane adducts, and tetra-aryl bis(phosphines) that can also be reduced to their corresponding alkali metal diaryl phosphide salts. The invention also relates to small molecule PAHs and polymer tethered PAHs naphthenics.

Enantioselective reduction of ketones with a silane agent/metal compound/chiral ligand system

A process for the enantioselective reduction of prochiral ketones to chiral alcohols by (a) the reaction of a prochiral ketone with a silane agent, which is present in a stoichiometric quantity, in the presence of a catalyst derived from a Zn, Co or Cd precursor compound and from a chiral amine, imine, alcohol or amino alcohol ligand; (b) the hydrolysis of the siloxane obtained using an appropriate agent; and (c) the separation and purification of the optically active alcohol formed. Polymethylhydrosiloxane (PMHS) is a preferred silane agent, zinc is a preferred metal, and the precursor compound is produced by reacting a salt or complex of the respective metal with the reducing agent. In another embodiment, an appropriate salt of the chosen metal is used directly in the reaction with the chiral ligand to produce the catalytic form after reaction with the ligand. The process enables high enantiomeric excesses (ee) to be obtained in chiral alcohols.

REDUKTION VON CARBONYLVERBINDUNGEN DURCH EIN SILANDERIVAT IN GEGENWART EINES ZINK-KATALYSATOR

Complexes and methods for their preparation

ENANTIOSELEKTIVE OXAZABOROLIDIN CATALYSTS

BY POLYMERS REGULAR WASSERBILDUNG

HYDROTREATING CATALYST, METHOD FOR PRODUCING THE CATALYST, AND HYDROTREATING PROCESS FOR HYDROCARBON OIL USING THE CATALYST

To provide a catalyst having hydrotreatment (hydrogenation, desulfurization and denitrification) performance that is equal to or superior to the prior art, as a hydrotreating catalyst for hydrocarbon oils, and a hydrotreating process for hydrocarbon oils using the catalyst. The catalyst comprises 10 to 40 mass% of at least one element of Group 6 of the Periodic Table, 0.5 to 15 mass% of at least one element of Groups 8 to 10 of the Periodic Table based on the oxide catalysts, and a 0.05- to 3-fold amount of an organic additive with respect to the total number of moles of the elements of Group 6 and Groups 8 to 10 of the Periodic Table, added to an inorganic porous support composed mainly of silica-alumina that comprises an oxide of a metal of Group 2 of the Periodic Table.

A SUPPORTED CATALYST, ITS ACTIVATED FORM, AND THEIR PREPARATION AND USE

A supported catalyst and preparation method thereof, the catalyst comprising an organic polymer material carrier, and Raney alloy particles supported on the organic polymer material carrier; basically all of the Raney alloy grains are partially embedded in the organic polymer material carrier. The catalyst can be used in hydrogenation, dehydrogenation, amination, dehalogenation or desulfurization reactions.

HYDROPROCESSING METHODS FOR BULK GROUP VIII/VIB METAL CATALYSTS

Hydrocarbon feedstocks are hydroprocessed in reaction systems including a t least one catalyst stage containing bulk metallic catalysts comprised of a Group VIII metal, a Group VIB metal, and an organic compound-based componen t. The catalysts are prepared by a method wherein precursors of both metals are mixed and interacted with at least one organic acid, such as glyoxylic a cid, dried, heated, and sulfided. The catalysts are used for hydroprocessing , particularly hydrodesulfurizaton and hydrodenitrogenation, of hydrocarbon feedstocks.

Regeneration of ionic liquid catalyst by hydrogenation using a metal or metal alloy catalyst

A process for regenerating a used acidic ionic liquid catalyst which has, been deactivated comprising the steps of contacting the used chloroaluminate ionic liquid catalyst and hydrogen with a metal hydrogenation catalyst in a reaction zone under hydrogenation conditions for a time sufficient to increase the activity of the ionic liquid catalyst is described. In one embodiment, hydrogenation is conducted in the presence of a hydrocarbon solvent.

PROCESS FOR THE SYNTHESIS OF 1,3-DIHYDRO-IMIDAZO[4,5-B]PYRIDIN-2-ONE AND/OR DERIVATIVES THEREOF

The present invention relates to a novel method of producing a compound of Formula (I) from a compound of formula (II) by a novel cyclisation process, as well as a method of producing an acid adduct of the compound of Formula (I) wherein L represents a leaving group, and R represents hydrogen, a substituted or unsubstituted linear, branched and/or cyclic alkyl group that may contain one or more hetero atoms in the linear, branched and/or cyclic alkyl chain, a substituted or unsubstituted aromatic or heteroaromatic group, a substituted or unsubstituted linear, branched and/or cyclic aralkyl or heteroaromatic alkyl group that may contain one or more hetero atoms in the linear, branched and/or cyclic alkanediyl chain, or a substituted or unsubstituted alkylaryl or alkyl heteroaromatic group with at least one linear, branched and/or cyclic alkyl residue that may contain one or more hetero atoms in the linear, branched and/or cyclic alkyl chain.

Optically active cyclic alcohol compound and method for preparing the same

The present invention relates to an optically active naphthalene compound represented by general formula [A]: wherein * represents an asymmetric carbon atom, or pharmaceutically acceptable salts thereof.

КАТАЛИЗАТОР НА НОСИТЕЛЕ, ЕГО АКТИВИРОВАННАЯ ФОРМА И ИХ ПОЛУЧЕНИЕ И ПРИМЕНЕНИЕ

Изобретение относится к катализатору на носителе, его активированной форме, их получению и применению. Описан неактивированный катализатор Ренея на носителе. Катализатор содержит органический полимерный материал-носитель и частицы сплава Ренея. Частицы сплава Ренея нанесены на полимерный материал-носитель, где по существу все частицы являются частично заделанными в материал-носитель. При этом в катализаторе частицы сплава Ренея распределены неравномерно и концентрация частиц в части поверхности этого носителя является большей, чем концентрация частиц сплава Ренея в средней части этого носителя. Активацию катализатора проводят посредством активирования каустическим водным раствором неактивированного катализатора на носителе. Технический результат – получение катализатора Ренея с высокой активностью, хорошей селективностью и легким извлечением металла. 5 н. и 12 з.п. ф-лы, 2 ил., 3 табл., 10 пр.

КОМПОЗИЦИЯ КАТАЛИЗАТОРА ДЛЯ ГИДРИРОВАНИЯ И СПОСОБ ГИДРИРОВАНИЯ С ЕЕ ИСПОЛЬЗОВАНИЕМ

... 1. Композиция катализатора для гидрирования, содержащая компоненты (A), (B), (C) и (D), показанные ниже,где массовое отношение (C) к (A) ((C)/(A)) находится в пределах от 0,1 до 4,0 игде массовое отношение (D) к (A) ((D)/(A)) находится в пределах от 0,01 до 1,00,(A) представляет собой титаноценовое соединение, представленное следующей общей формулой (1),где Rи Rпредставляют собой группу, выбранную из группы, состоящей из водорода, углеводородной группы, имеющей 1-12 атомов углерода, арилоксигруппы, алкоксигруппы, группы галогена и карбонильной группы, и Rи Rмогут быть одинаковыми или различными; и Rи Rпредставляют собой группу, выбранную из группы, состоящей из водорода и углеводородной группы, имеющей 1-12 атомов углерода, и Rи Rмогут быть одинаковыми или различными при условии, что не все Rи Rпредставляют собой атомы водорода или не все они представляют собой углеводородную группу, имеющую 1-12 атомов углерода,(B) представляет собой соединение, содержащее один или несколько элементов, ...

Supported catalyst and active form thereof, and preparation method and use

A supported catalyst and preparation method thereof, the catalyst comprising an organic polymer material carrier, and Raney alloy particles supported on the organic polymer material carrier; basically all of the Raney alloy grains are partially embedded in the organic polymer material carrier. The catalyst can be used in hydrogenation, dehydrogenation, amination, dehalogenation or desulfurization reactions.

Complexes and methods for their preparation

A method of preparing an amine according to Formula (I) comprising: preparing an amide of Formula (II); and reacting amide of Formula (II) to form amine of Formula (I), where the substituents are as defined in the claims. Preferably, Cy is a cyclohexadienyl group. Preferably RA is a toluenesulfonyl (tosyl) or triisopropylbenzenesulfonyl group. Preferably R8 and R9 are hydrogen or a phenyl group. Also claimed are amides according to Formula (II). Also claimed are complexes according to Formula (XI), where the complex (XI) is a complex according to formula (XIa) or (XIb), where the substituents are as defined in the claims. Also claimed is a method of catalysis, preferably for a transfer hydrogenation reaction, comprising reacting a substrate comprising a carbon-heteroatom double bond in the presence of a complex of Formula (XI).

PROCEDURE FOR THE EXECUTION OF CATALYTIC REACTIONS IN WAESSRIGEN MEDIA.

Enantioselective oxazaborolidine catalysts

POLYMER MODERATED WATER FORMATION

A composition suitable for safety removing hydrogen from gaseous mixtures containing hydrogen and oxygen, particularly those mixtures wherein the hydrogen concentration is within the explosive range. The composition comprises a hydrogenation catalyst, preferably Pd dispersed on carbon, wherein the concentration of Pd is from about 1-10 wt.%, dispersed in a polymeric material matrix. As well as serving as a matrix to contain the hydrogenation catalyst, the polymeric material, which is substantially unreactive to hydrogen, provides both a diffusion restriction to hydrogen and oxygen, thereby limiting the rate at which the reactants (hydrogen and oxygen) can diffuse to the catalyst surface and thus, the production of heat from the recombination reaction and as a heat sink.

POLYMER MODERATED WATER FORMATION

A composition suitable for safely removing hydrogen from gaseous mixtures containing hydrogen and oxygen, particularly those mixtures wherein the hydrogen concentration is within the explosive range. The composition comprises a hydrogenation catalyst, preferably Pd dispersed on carbon, wherein the concentration of Pd is from about 1-10 wt.%, dispersed in a polymeric material matrix. As well as serving as a matrix to contain the hydrogenation catalyst, the polymeric material, which is substantially unreactive to hydrogen, provides both a diffusion restriction to hydrogen and oxygen, thereby limiting the rate at which the reactants (hydrogen and oxygen) can diffuse to the catalyst surface and thus, the production of heat from the recombination reaction and as a heat sink.

METHOD FOR PRODUCING DIAMINE COMPOUND

The present invention provides a method for producing a compound represented by general formula (1) (wherein R1, R2, R3, R10-R14, A1-A3, n1 and n2 are as defined in the description), which is characterized by reacting a compound represented by general formula (2) (wherein R10-R14, A1-A3, n1, n2 and B are as defined in the description) with a diamine compound represented by general formula (3) (wherein R1-R3 are as defined in the description). The present invention is a method for producing a diamine compound, which is useful for the formation of a ruthenium-diamine complex, under mild conditions, said method being able to be put in industrial practice.

Azoxy cpds prepn by reducing nitro cpds - using polystyrene-supported metal complex catalyst, giving high yields

METAL COMPLEXES SUITABLE FOR ATTACHMENT TO A SUPPORT AND SUPPORTED METAL COMPLEXES

La présente invention concerne : un support fonctionnalisé intervenant dans la préparation d'un complexe métallique sur support et qui comprend une structure polymère possédant au moins un site fonctionnalisé capable de réagir et de se lier avec au moins un atome métallique ou un complexe métallique ; un complexe métallique sur support obtenu au moyen du support fonctionnalisé ; un complexe métallique comprenant au moins un atome métallique et un ligand pouvant être relié au support polymère ; et un complexe métallique sur support obtenu par liaison du complexe métallique sur un support polymère. L'invention concerne également l'utilisation de ces complexes métalliques comme catalyseurs.

OPTICALLY ACTIVE COBALT (II) OR (III) COMPLEXES, PROCESS FOR THE PREPARATION THEREOF AND INTERMEDIATES THEREFOR

Optically active cobalt (II) complexes represented by the general formulae (1) and (1'): (1) (1') wherein R1 and R2 are each independently hydrogen, linear or branched alkyl, linear or branched alkenyl, aryl, acyl, alkoxycarbonyl, aryloxycarbonyl, or aralkyloxycarbonyl, these groups being each optionally substituted; or alternatively R1 and R2 together with the carbon atoms to which R1 and R2 are bonded respectively may form a ring.

Regeneration of ionic liquid catalyst and recovery of an oil

A process for regenerating a used acidic ionic liquid catalyst, comprising: a. contacting the catalyst and hydrogen with a supported hydrogenation catalyst under hydrogenation conditions; and b. recovering a conjunct polymer that is a clear and colorless oil from the catalyst. A process for regenerating a used acidic ionic liquid catalyst which has been deactivated by conjunct polymers comprising the steps of contacting the used catalyst and hydrogen with a supported hydrogenation catalyst in a reaction zone under hydrogenation conditions in the presence of an inert hydrocarbon in which saturated conjunct polymers are soluble for a time sufficient to hydrogenate at least a portion of the conjunct polymers; and recovering the saturated conjunct polymers. Also, a process comprising: contacting the used acidic ionic liquid catalyst and hydrogen with a hydrogenation catalyst comprising a hydrogenation component under hydrogenation conditions; and recovering a conjunct polymer that is a clear ...

Reduction of carbonyl compounds by a silane in the presence of a zinc catalyst

A reductive system including a silane, preferably PMHS, and an active zinc compound, which is monomeric and not a hydride, wherein a reduction of a carbonyl substrate to a corresponding alcohol is achievable.

Liquid hydrogen storage material and method of storing hydrogen using the same

Provided is a liquid hydrogen storage material including 1,1′-biphenyl and 1,1′-methylenedibenzene, the liquid hydrogen storage material including the corresponding 1,1′-biphenyl and 1,1′-methylenedibenzene at a weight ratio of 1:1 to 1:2.5. The corresponding liquid hydrogen storage material has excellent hydrogen storage capacity value by including materials having high hydrogen storage capacity, and is supplied in a liquid state, and as a result, it is possible to minimize initial investment costs and the like required when the corresponding liquid hydrogen storage material is used as a hydrogen storage material in a variety of industries.

Chiral nitrogen-phosphorus ligands and their use for asymmetric hydrogenation of alkenes

The invention relates to a series of novel chiral nitrogen-phosphorus ligands of formulae (Ia) and (Ib): wherein R1-R3 and X are as defined herein. The invention also relates to chiral metal complexes prepared with these chiral nitrogen-phosphorus ligands. The chiral metal complexes are useful as catalysts for carrying out asymmetric hydrogenation.

ENZYME IMMOBILIZATION USING IRON OXIDE YOLK-SHELL NANOSTRUCTURE

This invention relates to a carrier for immobilizing a biocatalyst including a Fe2O3 yolk-shell structure, to an immobilized enzyme using the carrier, and to realizing an increase in the stability of the enzyme and stability in organic solvents by cross-linking the enzyme. According to this invention, the carrier for immobilizing a biocatalyst and the enzyme immobilized thereon can be reused, have increased stability, facilitate the control of reactivity, pH, and temperature, and can be widely useful in various biochemical engineering industries.

DURCH POLYMERE GEREGELTE WASSERBILDUNG

Katalytisch aktiver Träger

The invention relates to a catalytically active support characterized in that a catalytically active transition metal is immobilized on the polymer support and the support comprises functional groups which enable the educt to be bonded. The inventive support is particularly suitable for the reduction of solid-phase bonded organic compounds.

Hydroprocessing methods for bulk group VIII/VIB metal catalysts

Hydrocarbon feedstocks are hydroprocessed in reaction systems including at least one catalyst stage containing bulk metallic catalysts comprised of a Group VIII metal, a Group VIB metal, and an organic compound-based component. The catalysts are prepared by a method wherein precursors of both metals are mixed and interacted with at least one organic acid, such as glyoxylic acid, dried, heated, and sulfided. The catalysts are used for hydroprocessing, particularly hydrodesulfurizaton and hydrodenitrogenation, of hydrocarbon feedstocks.

A SUPPORTED CATALYST, ITS ACTIVATED FORM, AND THEIR PREPARATION AND USE

A supported catalyst and preparation method thereof, the catalyst comprising an organic polymer material carrier and Raney alloy particles supported on the organic polymer material carrier, wherein substantially all of the Raney alloy particles are partially embedded in the organic polymer material carrier. The catalyst can be used in hydrogenation, dehydrogenation, amination, dehalogenation or desulfuration reactions.

SUPPORTED HYDROTREATING CATALYSTS HAVING ENHANCED ACTIVITY

This invention provides supported catalysts comprising a carrier, phosphorus, at least one Group VI metal, at least one Group VIII metal, and a polymer. In the catalyst, the molar ratio of phosphorus to Group VI metal is about 1:1.5 to less than about 1:12, the molar ratio of the Group VI metal to the Group VIII metal is about 1:1 to about 5:1, and the polymer has a carbon backbone and comprises functional groups having at least one heteroatom. Also provided are a process for preparing such supported catalysts, as well as methods for hydrotreating, hydrodenitrogenation, and/or hydro desulfurization, using supported catalysts.

Reducing Dimérisation of made up unsaturated

루테늄계 촉매 및 방향족 또는 다중불포화 화합물의 선택적 수소화에서 이의 용도

... 본 발명의 목적은 다음을 포함하는 방향족 또는 다중불포화 화합물의 선택적 수소화에 적절한 촉매에 관련된다: - 지르코니아 담체(ZrO2) - 루테늄 - 산화 철(Fe2O3) - IB, IIB 및 IIIA 족 금속의 산화물로부터 선택되는 적어도 하나의 촉진제(A) - 다음의 금속 아렌으로부터 선택되는 적어도 하나의 전구체 P-B의 가수분해에 의하여 획득된, V, Ti, Hf, Zr 또는 이들의 혼합을 포함하는 적어도 하나의 촉진제(B) : V°(아렌)2 (I) V(아렌)2 AlCl4 (II) M(η6-아렌)pAlqXr (III) M(η6-아렌)p'Alq'Xr'Rs (IV) 여기서 - V는 바나듐을 나타내고, - Al은 알루미늄을 나타내고, - M은 지르코늄(Zr), 하프늄(Hf), 티타늄(Ti) 또는 이들의 혼합, 바람직하게는 티타늄 또는 지르코늄을 나타내고; - 아렌은 벤젠, 또는 1 내지 6 선형 또는 분지형 C1-C6 알킬기에 의하여 치환된 벤젠, 또는 이들의 혼합을 나타내고; - X는 클로린, 브로민, 플루오린, 아이오딘으로부터 선택되는 할로겐 원자, 바람직하게는 클로린을 나타내고; - R은 선형 또는 분지형 C1-C15 알킬기를 나타내고; - p는 1 내지 2 범위의 수를 나타내고; - q는 2 내지 6, 바람직하게는 2 내지 3 범위의 수이고; - r은 8 내지 20, 바람직하게는 8 내지 11 범위의 수이고; - p는 1 내지 2 범위의 수를 나타내고; - q'은 2 내지 6, 바람직하게는 2 내지 3 범위의 수이고; - r'은 2 내지 20, 바람직하게는 6 내지 9 범위의 수이고; - s는 1 내지 6 범위의 수, 바람직하게는 2이다. 본 발명의 촉매는 방향족 또는 다중불포화 화합물의 선택적 수소화 공정에서, 특히 벤젠 또는 사이클로헥센의 선택적 수소화에서 사용된다.

Regeneration of ionic liquid catalyst by hydrogenation using a supported catalyst

A process for regenerating a used acidic ionic liquid catalyst comprising the steps of contacting the used ionic liquid catalyst and hydrogen with a supported hydrogenation catalyst comprising a hydrogenation component on a support in a reaction zone under hydrogenation conditions for a time sufficient to increase the activity of the used catalyst is disclosed.

Composition and method for polymer moderated catalytic water formation

A composition suitable for safely removing hydrogen from gaseous mixtures containing hydrogen and oxygen, particularly those mixtures wherein the hydrogen concentration is within the explosive range. The composition comprises a hydrogenation catalyst, preferably Pd dispersed on carbon, wherein the concentration of Pd is from about 1-10 wt %, dispersed in a polymeric material matrix. As well as serving as a matrix to contain the hydrogenation catalyst, the polymeric material, which is substantially unreactive to hydrogen, provides both a diffusion restriction to hydrogen and oxygen, thereby limiting the rate at which the reactants (hydrogen and oxygen) can diffuse to the catalyst surface and thus, the production of heat from the recombination reaction and as a heat sink.

КОМПОЗИЦИЯ КАТАЛИЗАТОРА ДЛЯ ГИДРИРОВАНИЯ И СПОСОБ ГИДРИРОВАНИЯ С ЕЕ ИСПОЛЬЗОВАНИЕМ

Изобретение относится к композиции катализатора для гидрирования. Композиция содержит компоненты (А), (В), (С) и (D), где массовое отношение (С) к (А) ((С)/(А)) находится в пределах от 0,1 до 4,0 и где массовое отношение (D) к (А) ((D)/(А)) находится в пределах от 0,01 до 1,00. (A) представляет собой титаноценовое соединение, представленное следующей общей формулой (1),,где Rи Rпредставляют собой группу, выбранную из группы, состоящей из водорода, углеводородной группы, имеющей 1-12 атомов углерода, арилоксигруппы, алкоксигруппы, группы галогена и карбонильной группы, и Rи Rмогут быть одинаковыми или различными; и Rи Rпредставляют собой группу, выбранную из группы, состоящей из водорода и углеводородной группы, имеющей 1-12 атомов углерода, и Rи Rмогут быть одинаковыми или различными; при условии, что не все Rи Rпредставляют собой атомы водорода или не все они представляют собой углеводородную группу, имеющую 1-12 атомов углерода. (B) представляет собой соединение, содержащее один или несколько ...

Complexes and methods for their preparation

Process for reduction with boron compounds

Example 1 describes the preparation of a copper sol by adding pearl glue solution to aqueous or ammoniacal copper sulphate solution and then reducing with potassium borohydride. Example 4 describes the preparation in an analogous manner of a silver sol from silver nitrate solution.ALSO:Example 23 describes the preparation of asymmetrical dimethyl hydrazine by reducing nitrosodimethyl amine with sodium borohydride in the presence of a catalyst comprising an ammoniacal copper sol, a complex of copper chloride and aminoacetic acid or a complex potassium nickel cyanide together with pearl glue solution. Example 26 describes the reduction of nitrobenzene with sodium borohydride in the presence of a copper sol as catalyst to yield aniline together with small amounts of azobenzene and azoxybenzene, or when the catalyst is a complex potassium nickel cyanide or sodium anthraquinone-2-sulphonate, to yield azo benzene together with a small amount of azoxybenzene. In an analagous manner, nitrobenzene ...

Supported catalyst and active form thereof, and preparation method and use thereof

A supported catalyst and preparation method thereof, the catalyst comprising an organic polymer material carrier, and Raney alloy particles supported on the organic polymer material carrier; basically all of the Raney alloy grains are partially embedded in the organic polymer material carrier. The catalyst can be used in hydrogenation, dehydrogenation, amination, dehalogenation or desulfurization reactions.

CHIRAL METAL COMPLEX COMPOUNDS

The invention comprises novel chiral metal complex compounds of the formula (I) wherein M, PR2, R3 and R4 are outlined in the description, its stereoisomers, in the form as a neutral complex or a complex cation with a suitable counter ion. The chiral metal complex compounds can be used in asymmetric reactions, particularly in asymmetric reductions of ketones, imines or oximes.

HOMOGENEOUS HYDROGENATION OF ESTERS EMPLOYING A COMPLEX OF IRON AS CATALYST

The homogeneous hydrogenation of organic carbonyls, especially esters, under relatively mild conditions using iron hydrido-borohydride catalyst complexes having amino-phosphine pincer ligands. The catalyst and process are well-suited for catalyzing the hydrogenation of a wide variety of organic carbonyls, such as hydrogenation of fatty acid esters to alcohols. In particular embodiments, the process can be carried out in the absence of solvent.

REDUCTION OF CARBONYL COMPOUNDS BY A SILANE IN THE PRESENCE OF A ZINC CATALYST

The object of the present invention is a process for the preparation of alcohols by reduction of the carbonyl function in substrates belonging to the class of aldehydes, ketones, esters or lactones, which substrates may contain unsaturated functions other than carbonyl, comprising: a) the reaction of the carbonyl substrate with stoichiometric amounts of a silane in the presence of catalytic amounts of an active zinc compound which is monomeric and not a hydride, b) the hydrolysis of the thus-obtained siloxane with a basic agent, and c) the separation and purification, if necessary, of the thus-obtained alcohol. The catalytically active compound is generally obtained by the reaction of an oligomeric or polymeric precursor compound of zinc with a complexing agent.

Preparation method and application for high-activity hydrogenation reaction catalyst

Process to carry out catalytic reactions in an aqueous medium

... 1. Process for carrying out catalytic reactions in aqueous media by means of ion exchangers charged with catalytically active elements (catalyst resins), characterised in that the ion exchanger charged with the catalytically active elements (catalyst resin) is used simultaneously as a catalyst and for the adsorption of the ions present in the aqueous medium and the exchange-active groups of the ion exchanger charged with catalytically active elements (catalyst resin) are regenerated as soon as they are exhausted.

Verfahren zur Reduktion mit Boranaten

Chiral metal complex compounds

The invention comprises novel chiral metal complex compounds of the formula (I) wherein M, PR ...

TRANSITION METAL CATALYSTS FOR C-O HYDROGENOLYSIS AND HYDRODEOXYGENATION

Phosphoranimide-metal catalysts and their role in C-O bond hydrogenolysis and hydrodeoxygenation (HDO) are disclosed. The catalysts comprise of first row transition metals such as nickel, cobalt and iron. The catalysts have a metal to anionic phosphoranimide ratio of 1:1 and catalyze C-O bond hydrogenolyses of a range of oxygen-containing organic compounds under lower temperature and pressure conditions than those commonly used in industrial hydrodeoxygenation.

4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES

Prochiral ketones are enantioselectively reduced to chiral secondary alcohols with a compound having the formula I: where, the two R2 groups are identical and are each a substituted or unsubstituted, aryl, alkyl, cycloalkyl or aralkyl group; and R3 is a hydrogen atom or a substituted or unsubstituted, alkyl, aryl, aralkyl or alkoxy group; wherein the substituents on the R2 and R3 groups are substantially non-reactive.

HYDROPROCESSING METHODS FOR BULK GROUP VIII/GROUP VIB METAL CATALYSTS

Hydrocarbon feedstocks are hydroprocessed in reaction systems including at least one catalyst stage containing bulk metallic catalysts comprised of a Group VIII metal, a Group VIB metal, and an organic compound-based component. The catalysts are prepared by a method wherein precursors of both metals are mixed and interacted with at least one organic acid, such as glyoxylic acid, dried, heated, and sulfided. The catalysts are used for hydroprocessing, particularly hydrodesulfurizaton and hydrodenitrogenation, of hydrocarbon feedstocks.

4-CYCLOHEXYL-1,3,2-OXAZABOROLIDINE CHIRAL ACCESSORIES

Prochiral ketones are enantioselectively reduced to chiral secondary alcohols with a compound having the formula I: where, the two R2 groups are identical and are each a substituted or unsubstituted, aryl, alkyl, cycloalkyl or aralkyl group; and R3 is a hydrogen atom or a substituted or unsubstituted, alkyl, aryl, aralkyl or alkoxy group; wherein the substituents on the R2and R3 groups are substantially non-reactive.

Catalyst composition for hydrogenation and method for hydrogenation using the same

A catalyst composition for hydrogenation including (A) to (D), in which a mass ratio ((C)/(A)) is 0.1 to 4.0 and a mass ratio ((D)/(A)) is 0.01 to 1.00, (A): a titanocene compound represented by formula (1), (wherein R5and R6are any group selected from hydrogen, a hydrocarbon group having 1 to 12 carbon atoms, an aryloxy group, an alkoxy group, a halogen group, and a carbonyl group. R1and R2are any group selected from the group consisting of hydrogen and a hydrocarbon group having 1 to 12 carbon atoms, and R1and R2are not all hydrogen atoms or all a hydrocarbon group having 1 to 12 carbon atoms), (B): a reductant formed from a compound containing an element selected from the elements Li, Na, K, Mg, Zn, Al, and Ca, (C): an unsaturated compound having a molecular weight of 400 or less, and (D): a polar compound.

PRODUCTION METHOD FOR OPTICALLY ACTIVE ALCOHOL COMPOUND

A method for stereoselectively producing an optically active alcohol compound. The optically active alcohol compound of Formula (8) can be produced in high yield and high selectivity from the compound of Formula (3), and the production method that is useful industrially and the intermediates therefor can be provided. In formulae, Ris a hydrogen atom, Calkyl, Calkyl optionally substituted with R, or the like, Ris cyano or —CHN(R)R, and Ris Ccycloalkyl. 2. The method for producing the optically active alcohol compound according to claim 1 , wherein Ris a hydrogen atom claim 1 , (C) alkyl optionally substituted with R claim 1 , —C(O)R— claim 1 , or —Si(R)(R)R.3. The method for producing the optically active alcohol compound according to claim 2 , wherein the reaction is carried out in the presence of the optically active ruthenium catalyst of Formula (4).4. The method for producing the optically active alcohol compound according to claim 3 , wherein{'sup': 2', '5', '4, 'sub': '2', 'Ris —CHN(R)R;'}{'sup': 4', '6', '7, 'Ris —C(O)Ror —C(O)OR;'}{'sup': '6', 'sub': 1-6', '1-6, 'Ris Calkyl or (C) alkyl optionally substituted with a halogen atom; and'}{'sup': '8', 'sub': 1-6', '1-6, 'Ris a hydrogen atom, Calkyl, or (C) alkyl optionally substituted with a halogen atom.'}5. The method for producing the optically active alcohol compound according to claim 4 , wherein{'sup': 1', '3', '12a', '12b', '12, 'sub': '1-6', 'Ris (C) alkyl optionally substituted with R, or —Si(R)(R)R;'}{'sup': '3', 'sub': '3-8', 'Ris phenyl, or Ccycloalkyl;'}{'sup': 5', '5', '4', '5', '4, 'sub': '4', 'Ris a hydrogen atom, or Roptionally forms a 5-membered ring together with a nitrogen atom to which Rand Rare bonded by forming a Calkylene chain together with R, and in this case the alkylene chain is optionally substituted with an oxo group, or the alkylene chain optionally forms phenyl together with carbon atoms to which two substituents each bond when the two substituents exist at adjacent positions on ...

4-Cyclohexyl-1,3,2-oxazaborolidine chiral accessories

Prochiral ketones are enantioselectively reduced to chiral secondary alcohols with a compound having the formula I:where, the two R2 groups are identical and are each a substituted or unsubstituted, aryl, alkyl, cycloalkyl or aralkyl group; and R3 is a hydrogen atom or a substituted or unsubstituted, alkyl, aryl, aralkyl or alkoxy group; wherein the substituents on the R2 and R3 groups are substantially non-reactive.

ENANTIOSELECTIVE REDUCTION OF KETONES WITH A SILANE AGENT/METAL COMPOUND/CHIRAL LIGAND SYSTEM

The invention concerns a method for the enantioselective reduction of prochiral ketones into chiral alcohol's comprising the following steps: a) reacting a prochiral ketone with a silane agent, present in stoichimetric amount, in the presence of a catalyst derived from a precursor compound of Zn, Co or Cd and of a chiral ligand selected from the group consisting of chiral amines, imines, alcohol's or aminoalcohol's; b) hydrolysis of resulting siloxane using an appropriate agent; c) separating and purifying the resulting optically active alcohol. In one preferred embodiment, polymethylhydrosiloxane (PMHS) is used as silane agent. The preferred metal is Zn. The precursor compound is produced by reacting a salt or complex of the particular metal with a reducing agent; in another embodiment, an appropriate salt of the selected metal is used in the reaction with the chiral ligand, to produce the catalytic agent, after reaction with the ligand. The method is useful for obtaining high enantiomeric ...

Amalgam Hydrodimerisation of Unsaturated Compounds

... 1,163,422. Reductive dimerization of unsaturated esters and nitriles. IMPERIAL CHEMICAL INDUSTRIES Ltd. 11 Oct., 1966 [1 Nov., 1965], No. 46131/65. Heading C2C. ,#-Olefinically unsaturated esters or nitriles are reductively dimerized by means of an alkali- or alkaline-earth metal amalgam reduction system, wherein the ester or nitrile is contained in a polar aprotic organic solvent system that incorporates less than 50% by wt. of a proton source (which co-operates with the amalgam to provide said reduction system) and a quantity of halide ions, furnished by an anion-exchange resin bearing quaternized amine groups and wherein the apparent pH of the organic medium is controlled at a value not less than 7 by supplying hydrogen chloride gas. The preferred halide ions are chloride ions and the resin is suitably a polystyrene resin bearing methyl quaternized amine groups. The preferred proton source is water and the polar solvent (which may be acetonitrile, dimethyl formamide or dimethyl sulphoxide ...

CYCLOOLEFINIC COMPLEXES OF PLATINUM, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS A CATALYST

Docket No. Co 8809 Paper No. 1 CYCLOOLEFINIC COMPLEXES OF PLATINUM, PROCESSES FOR PREPARING THE SAME AND THEIR USE AS A CATALYST The invention relates to cycloolefinic complexes of platinum, processes for preparing the same from platinum(II) compounds and cycloolefins having at least 12 ring carbon atoms and at least two aliphatic non-cumulated carbon-carbon double bonds and their use as a catalyst for the addition of Si-bonded hydrogen to an aliphatic multiple bond.

ENANTIOSELECTIVE REDUCTION OF KETONES WITH A SILANE AGENT/METAL COMPOUND/CHIRAL LIGAND SYSTEM

The invention concerns a method for the enantioselective reduction of prochiral ketones into chiral alcohol's comprising the following steps: a) reacting a prochiral ketone with a silane agent, present in stoichimetric amount, in the presence of a catalyst derived from a precursor compound of Zn, Co or Cd and of a chiral ligand selected from the group consisting of chiral amines, imines, alcohol's or aminoalcohol's; b) hydrolysis of resulting siloxane using an appropriate agent; c) separating and purifying the resulting optically active alcohol. In one preferred embodiment, polymethylhydrosiloxane (PMHS) is used as silane agent. The preferred metal is Zn. The precursor compound is produced by reacting a salt or complex of the particular metal with a reducing agent; in another embodiment, an appropriate salt of the selected metal is used in the reaction with the chiral ligand, to produce the catalytic agent, after reaction with the ligand. The method is useful for obtaining high enantiomeric ...

Preparation method of 5-hydroxymethylfurfural decarbonylation catalyst

Azoxy cpds prepn by reducing nitro cpds - using polystyrene-supported metal complex catalyst, giving high yields

Reduction of carbonyl compounds by a silane in the presence of a zinc catalyst

A reductive system including a silane, preferably PMHS, and an active zinc compound, which is monomeric and not a hydride, wherein a reduction of a carbonyl substrate to a corresponding alcohol is achievable.

Compositions and methods for facilitating reaction at room temperature

Compositions and methods useful in facilitating or conducting a reaction at effective conditions, such as room temperature (e.g. about 70 degrees F.), utilize a compound including at least two different heteroatoms, and optionally a heterocycle, and a transition metal. The compound is effective in facilitating a variety of reactions including hydrolysis reactions, alcoholysis reactions, aminolysis reactions, carbon dioxide conversion reactions, hydroamination reactions, hydration reactions, and the like.

METHOD FOR PRODUCING AROMATIC COMPOUND

The present invention is a method for producing an aromatic compound by substituting the sulfonic acid group in a sulfonic acid aromatic-ester with a hydrogen atom in the presence of a platinum group metal catalyst, wherein an alkali metal carboxylate and/or an ammonium formate are made to coexist in the system. According to the present invention, an aromatic compound where the sulfonic acid group in a sulfonic acid aromatic-ester is substituted with a hydrogen atom, can be produced efficiently with good operability without using metal magnesium.

OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME

The present invention relates to a method for preparing an optically active cyclic alcohol compound represented by general formula [I]: [wherein R represents a hydrogen atom or a protecting group for amino group, and * represents an asymmetric carbon atom.] which comprises a step of subjecting a cyclic ketone compound represented by general formula [II]: [wherein R has the same meaning as defined above.] to asymmetric reduction (A) in the presence of an optically active oxazaborolidine compound and a boron hydride compound, or (B) in the presence of an asymmetric transition metal complex obtained from a transition metal compound and an asymmetric ligand and a hydrogen donor, and relates to said compound.

Bulk catalysts having increased stability

Bulk catalysts that include a Group VI metal, a Group VIII metal, and at least 10-60% of an organic compound based component are formed. The bulk catalysts have increased stability through the use of a stabilizer in the organic compound based component, the use of an improved gas phase sulfidation, or a combination thereof. The bulk catalysts are suitable for hydroprocessing of hydrocarbon feeds.

CHIRAL CATALYST AND METHOD FOR ASYMMETRIC REDUCTION OF AN IMINE

The present disclosure discusses (i) a compound having a chemical formula according to Formula (I), or its enantiomer; and (ii) a compound that is reactive with a hydride to produce a compound having a chemical formula according to Formula (I), or its enantiomer. Formula (I) is: Formula (I) where R1and R2are H, optionally substituted C1-C3alkyl, or linked together to form an optionally substituted C3or C4alkyl group; R3and R3′are H; R4and R4′ are the same, and are optionally substituted C1-C6alkyl; and R5and R5′ are the same, and are optionally substituted aryl or heteroaryl. In some examples, R4 and R5 are linked, and R4′ and R5′ are linked, where both linking groups are the same. The present disclosure also discusses methods of asymmetric reduction of an imine, and methods of forming the catalysts and pre-catalysts.

Improvements in and relating to amino rhodium compounds

Polymer moderated water formation

4-cyclohexyl-1,3,2-oxazaborolidine chiral accessories

Hydroprocessing methods for bulk group VIII/VIB metal catalysts

Supported hydrotreating catalysts having enhanced activity

This invention provides supported catalysts comprising a carrier, phosphorus, at least one Group VI metal, at least one Group VIII metal, and a polymer. In the catalyst, the molar ratio of phosphorus to Group VI metal is about 1:1.5 to less than about 1:12, the molar ratio of the Group VI metal to the Group VIII metal is about 1:1 to about 5:1, and the polymer has a carbon backbone and comprises functional groups having at least one heteroatom. Also provided are a process for preparing such supported catalysts, as well as methods for hydrotreating, hydrodenitrogenation, and/or hydro desulfurization, using supported catalysts.

ENANTIOSELECTIVE OXAZABOROLIDINE CATALYSTS

The enantioselective borane reduction of prochiral ketones to optically pure alcohols is effectively achieved by performing the reduction in the presence of catalytic amounts of the new and valuable oxazaborolidine compounds of formulae (I) and (II). The compounds of formulae (I) and (II) may be isolated and purified prior to use in the reduction reactions or the compounds of formulae (I) and (II) may be generated in situ.

GROUP 13-15 INTERSTITIAL METAL HYDRIDE CATALYSTS AND ASSOCIATED PROCESSES

The present invention relates to the processing of hydrocarbon-containing feedstreams in the presence of an interstitial metal hydride comprised of at least one chemical element selected from Groups 3-11 (including the lanthanides, atomic numbers 58 to 71), and at least one chemical element selected from Groups 13-15 from the IUPAC Periodic Table of Elements. These interstitial metal hydrides, their catalysts and processes using these interstitial metal hydrides and catalysts of the present invention improve overall hydrogenation, product conversion, as well as sulfur reduction in hydrocarbon feedstreams.

SYNTHESIS AND ORGANIZATION OF GOLD-PEPTIDE NANOPARTICLES FOR CATALYTIC ACTIVITIES

A facile strategy is used to synthesize the gold nanoparticles via a green and simple approach showing self-alignment on the assembled nanofibers of ultrashort oligopeptides as a composite material. A photochemical reduction method is used, without requiring any external chemical reagents for the reduction of gold ions and producing gold nanoparticles of size ca. 5 nm under mild UV light exposure. The specific arrangement of gold nanoparticles on peptide nanofibers may indicate electrostatic interactions of two components and interactions with the amino group of the peptide building block. The gold-peptide nanoparticle composites show the ability as a catalyst to degradation of environmental pollutant p-nitrophenol to p-aminophenol, and the reaction rate constant for catalysis is 0.057 min−1at a 50-fold dilute sample of 2 mg/mL and 0.72 mM gold concentration in the composites. This colloidal strategy helps researchers to fabricate the metalized bioorganic composites for biomedical and bio-catalysis ...

REDUKTION VON CARBONYLVERBINDUNGEN DURCH EIN SILANDERIVAT IN GEGENWART EINES ZINK-KATALYSATOR

Process for producing aryl hydroxylamine

... 本发明的课题是提供种在温和的条件下有效且安全地制造芳基羟基胺化合物的方法。本发明的解决课题的方法是提供种芳基羟基胺化合物的制造方法，其特征在于，在氨基配位的二氧化硅负载铂催化剂和毒性剂的存在下，使硝基芳基化合物和氢源接触。 ...

Application of tris(2,2'-bipyridyl)ruthenium(II) chloride hexahydrate as catalyst

DIVALENT LANTHANIDE REDUCTION CATALYSTS

La présente invention concerne, de manière générale, la composition chimique de catalyseurs de réduction inorganiques, et en particulier, la composition et l'utilisation des catalyseurs lanthanides dihalogénés, par exemple TmI¿2 ou DyI¿2, pour faciliter les réactions de réduction, notamment la préparation d'hydrocarbures alkylés et/ou de polymères organiques.

Transfer Hydrogenation of Cyclopamine Analogs

Provided herein is a process for the transfer-hydrogenation of ketone analogs of members of the jervine type of Veratrum alkaloids, such as cyclopamine. Also provided herein are novel ruthenium transfer-hydrogenation catalysts.

Supported metal catalysts

The present invention relates to supported metal catalysts, wherein the catalysts are modified by at least one amine, a method for the preparation thereof and hydrogenation processes utilising the supported metal catalysts.

Method for producing alcohol and/or amine from amide compound

Disclosed herein is a method for producing an alcohol and an amine from an amide under an atmosphere of hydrogen with the use of, as a catalyst, a ruthenium complex that is easily prepared, easy to handle, and relatively cheaply obtained. Specifically, the method is a method for producing an alcohol and/or an amine from an amide compound under an atmosphere of hydrogen with the use of as a catalyst, a ruthenium carbonyl complex represented by the following general formula (1): RuXY(CO)(L) (1) wherein X and Y may be the same or different from each other and each represents an anionic ligand and L represents a tridentate aminodiphosphine ligand containing two phosphino groups and a —NH— group.

Catalytic conversion of cellulose to fuels and chemicals using boronic acids

Methods and catalyst compositions for formation of furans from carbohydrates. A carbohydrate substrate is heating in the presence of a 2-substituted phenylboronic acid (or salt or hydrate thereof) and optionally a magnesium or calcium halide salt. The reaction is carried out in a polar aprotic solvent other than an ionic liquid, an ionic liquid or a mixture thereof. Additional of a selected amount of water to the reaction can enhance the yield of furans.

Novel ruthenium complexes and their uses in processes for formation and/or hydrogenation of esters, amides and derivatives thereof

The present invention relates to novel Ruthenium catalysts and related borohydride complexes, and the use of such catalysts, inter alia, for (1) hydrogenation of amides (including polyamides) to alcohols and amines; (2) preparing amides from alcohols with amines (including the preparation of polyamides (e.g., polypeptides) by reacting dialcohols and diamines and/or by polymerization of amino alcohols); (3) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones) or cyclic di-esters (di-lactones) or polyesters); (4) hydrogenation of organic carbonates (including polycarbonates) to alcohols and hydrogenation of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (5) dehydrogenative coupling of alcohols to esters; (6) hydrogenation of secondary alcohols to ketones; (7) amidation of esters (i.e., synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water to form carboxylic acids; and (10) dehydrogenation of beta-amino alcohols to form pyrazines. The present invention further relates to the novel uses of certain pyridine Ruthenium catalysts.

Method For Producing Beta-Fluoroalcohol

A production method of a β-fluoroalcohol includes performing a reaction of an α-fluoroester with hydrogen gas (H 2 ) in the presence of a specific ruthenium complex (i.e. a ruthenium complex of the general formula [2], preferably a ruthenium complex of the general formula [4]). This production method can employ a suitable hydrogen pressure of 1 MPa or less by the use of such a specific ruthenium complex and does not require a high-pressure gas production facility when put in industrial practice. In addition, this production method can remarkably reduce the amount of catalyst used therein (to e.g. a substrate/catalyst ratio of 20,000) in comparison to the substrate/catalyst ratio conventional reduction of α-fluoroalcohol. It is possible by these reduction in hydrogen pressure and catalyst amount to largely reduce the production cost of the β-fluoroalcohol.

COMPOSITION HAVING AN ACTIVE METAL OR PRECURSOR, AN AMINE COMPONENT AND A NON-AMINE CONTAINING POLAR ADDITIVE USEFUL IN THE CATALYTIC HYDROPROCESSING OF HYDROCARBONS, A METHOD OF MAKING SUCH CATALYST, AND A PROCESS OF USING SUCH CATALYST

A composition that comprises a support material that is loaded with an active metal or metal precursor, an amine component, and a non-amine containing polar additive. The composition is useful in the hydroprocessing of hydrocarbon feedstocks. The composition is prepared by incorporating a metal solution into a support material followed by incorporating therein an amine component and a non-amine containing polar additive. 1. A method of making a composition , wherein said method comprises: incorporating a metal-containing solution into a support material to provide a metal-incorporated support material; and incorporating both an amine component and a non-amine containing polar additive into said metal-incorporated support material to thereby provide an impregnated composition comprising said support material , said amine component , and said non-amine containing polar additive.2. A method as recited in claim 1 , further comprising: contacting said impregnated composition under suitable hydrogen treatment conditions with hydrogen to thereby provide a hydrogen-treated composition.3. A method as recited in claim 2 , wherein prior to said incorporating of said amine component and said non-amine containing polar additive into said metal-incorporated support material claim 2 , said metal-incorporated support material is dried so as to contain a volatiles content in the range of from 3 to 20 wt. % LOI.4. A method as recited in claim 1 , wherein the weight ratio of said non-amine containing polar additive to said amine component is in the range of upwardly to 10:1; wherein said amine component is selected from the group of compounds consisting of ether amine compounds claim 1 , alkyl amine compounds claim 1 , and amine oxide compounds; and wherein said amine compound has a molecular weight greater than 160 and a flash point of at least 80° C.5. A method as recited in claim 4 , wherein said amine component is an ether amine compound.6. A method as recited in claim 5 , wherein ...

Immobilized Ruthenium-Triphos Catalysts for Selective Hydrogenolysis of Amides

A compound represented by the structure of formula (I): 5. The compound of claim 4 , wherein L comprises trimethylenemethane.7. The method of claim 6 , wherein the Ru-containing compound comprises [Ru(COD)(methylallyl)].8. A catalyst composition comprising:(a) an oxidic support; and{'claim-ref': {'@idref': 'CLM-00004', 'claim 4'}, '(b) the compound of immobilized on the support.'}9. The catalyst composition of claim 8 , wherein the oxidic support comprises silica claim 8 , magnesia claim 8 , titania claim 8 , or alumina.10. The catalyst composition of claim 8 , wherein the oxidic support comprises silica.11. The catalyst composition of claim 8 , wherein L comprises trimethylenemethane.13. The process of claim 12 , wherein the oxidic support comprises silica claim 12 , magnesia claim 12 , titania claim 12 , and alumina.14. The process of claim 12 , wherein the oxidic support comprises silica.15. The process of claim 12 , wherein L comprises trimethylenemethane.16. The process of claim 13 , wherein L comprises trimethylenemethane.17. The process of claim 14 , wherein L comprises trimethylenemethane.18. The process of claim 12 , wherein the amide comprises a lactam.19. The process of claim 13 , wherein the amide comprises a lactam.20. The process of claim 17 , wherein the amide comprises a lactam. This is application claims the benefit of Provisional Application No. 62/691,936 filed on Jun. 29, 2018 under 35 U.S.C. § 119(e)(1); the entire content of the provisional application is hereby incorporated by reference.The invention generally relates to the field of organic chemistry. It particularly relates to silyl ether triphos compounds, organometallic complexes containing the silyl ether triphos compounds, catalysts containing the organometallic complexes immobilized on oxidic supports, methods of making, and/or methods of using the compounds, complexes, and catalysts.The hydrogenolysis of amides to amines under mild reaction conditions represents a challenging chemical ...

PROCESS FOR THE PREPARATION OF CHIRAL 3-AMINO-PIPERIDINS, USEFUL INTERMEDIATES FOR THE PREPARATION OF TOFACITINIB

Object of the present invention is an improved process for the preparation of (3R,4R)-1-benzyl-4-methylpiperidin-3-amine by means of chiral Rhodium catalysts. 2. The process according to the claim 1 , wherein the compound of formula (II) or salt thereof has an enantiomeric excess higher than 67% claim 1 , or of at least 70%.3. The process according to claim 1 , wherein the Rh(I) complex is a neutral complex of the general formula (IVa) or (IVb):{'br': None, 'sub': '2', '[RhLA]\u2003\u2003(IVa) or'}{'br': None, 'sub': '2', '[RhLA]\u2003\u2003(IVb),'}{'sub': 4-12', '2-12, 'wherein L represents a Cdiene or two Calkene molecules, and A is chlorine, bromine, iodine, trifluoromethanesulfone, tetrafluoroboarte or acetylacetonate.'}4. The process according to the claim 3 , wherein L is norbornadiene or 1 claim 3 ,5-cyclooctadiene.5. The process according to claim 3 , wherein A is trifluoromethansulfone.8. The process according to claim 1 , wherein the asymmetrical hydrogenation is carried out at a temperature from 30° C. to 60° C. and the solvent is 2 claim 1 ,2 claim 1 ,2-trifluoroethanol claim 1 , or is carried out at a temperature from 50° C. to 70° C. and the solvent is methanol.9. The process according to claim 1 , wherein the asymmetrical hydrogenation is carried out in 2 claim 1 ,2 claim 1 ,2-trifluoroethanol and the pressure is from 2 to 15 bar claim 1 , or is carried in methanol and the pressure is from 10 to 20 bar.10. The process according to claim 1 , wherein the asymmetrical hydrogenation is carried out in from 5 to 10 volumes of 2 claim 1 ,2 claim 1 ,2-trifluoroethanol or from 10 to 20 volumes of methanol.17. The process according to claim 4 , wherein A is trifluoromethansulfone. This application claims benefit to European Patent Application No. EP17178755.9, filed Jun. 29, 2017, the entire contents of which are incorporated by reference herein as if fully set forth.The object of the present invention is an improved process for the synthesis of a key ...

INORGANIC/POLYMERIC HYBRID CATALYTIC MATERIALS WITH HIGH ACTIVITY IN VARIOUS SOLVENTS

Catalytic materials, particularly membranes, exhibiting high activity, high stability and low metal leaching in a variety of chemical reactions, particularly selective hydrogenations of unsaturated organic compounds, are described. These membranes are inorganic/polymeric hybrid materials in which metal complex molecular catalysts are immobilized or metal nano-particle catalysts are embedded. More specifically, the catalytic materials of the present invention exhibit higher activity and selectivity, and can be used in more extensive kinds of organic solvents than the conventional hybrid catalytic materials due to improvement in the affinity to organic solvents by containing the specific polymeric additives. 1. Catalytic material exhibiting catalytic activity in chemical reactions and consisting of a hybrid compound composed of metal oxides and polyvinyl alcohol or its derivatives , wherein metal complex molecular catalysts are immobilized and/or metal particle catalysts are embedded in the hybrid compound , and the hybrid compound contains polymeric additives more hydrophobic than polyvinyl alcohol.2. Catalytic material according to claim 1 , wherein the polymeric additives have a unit of —CH—CH—O— and a branch structure therein.3. Catalytic material according to claim 2 , wherein the polymeric additives having a unit of —CH—CH—O— and a branch structure is polyoxyethylene/polyglyceryl ether.4. Catalytic material according to claim 1 , wherein the polymeric additives have a unit of —Si(CH)—O— with carboxyl groups added to part of silicon atoms.5. Catalytic material according to claim 1 , wherein the metal oxides in the inorganic/polymeric hybrid compound include at least one selected from silicic acid compound claim 1 , tungstic acid compound and zirconic acid compound.614-. (canceled)15. Catalytic material according to claim 1 , wherein the metal particle catalysts are at least one selected from iron claim 1 , cobalt claim 1 , nickel claim 1 , copper claim 1 , ...

WATER-INSOLUBLE RUTHENIUM CATALYST COMPOSITION FOR USE IN AQUEOUS HYDROGENATION REACTIONS

The invention relates to a method for converting a precatalyst complex to an active catalyst complex, wherein the precatalyst complex and the active catalyst complex comprise a ruthenium atom and an optically active ligand that is insoluble in water, and the active catalyst complex furthermore comprises a monohydride and a water molecule. The method comprises the steps of providing water as an activation solvent system with a pH value equal or below 2, and solving said precatalyst complex, an acid, and hydrogen therein. The invention further relates to a method for manufacturing a catalyst composition, a method for hydrogenating a substrate molecule and a reaction mixture. 1. A method for converting a precatalyst complex to an active catalyst complex ,wherein said precatalyst complex and said active catalyst complex comprise a ruthenium atom and an optically active ligand that is insoluble in water, andwherein said active catalyst complex comprises a monohydride and a water molecule,said method comprising the steps of:a) providing an activation solvent system comprising water, said precatalyst complex,', 'a solubilizer,', 'an acid, and', 'hydrogen,, 'b) adding to, particularly solving in, said activation solvent system'}characterized in thatthe pH value of said activation solvent system is equal or below 2 after addition of said acid.2. The method according to claim 1 , wherein said activation solvent system comprises ≧50% (v/v) claim 1 , ≧75% (v/v) claim 1 , ≧80% (v/v) claim 1 , ≧90% (v/v) claim 1 , ≧99% (v/v) or 100% water.3. The method according to claim 1 , wherein said solubilizer is a surfactant that is capable of forming micelles in water and that is resistant to hydrolysis at pH≦2.4. A method for obtaining a catalyst composition claim 1 , comprising the steps ofa) providing water as a preparation solvent system, andb) adding to, particularly solving in, said preparation solvent system an optically active ligand, wherein said optically active ligand is ...

METHOD FOR REDUCTION OF ORGANIC MOLECULES

A method for the reduction organic molecules comprising a Ruthenium-Triphosphine complex with aromatic ligands at the phosphors which are ortho or meta substituted. 1. A method for the reduction of organic molecules , comprising the step ofa) hydrogenating at least one organic molecule in the presence of a Ruthenium-Triphosphine-complex whereby the triphosphine-complex comprises at least one aryl and/or heteroaryl moeity bound to a phosphine which is substituted in ortho and/or meta position to the phosphine.2. The method according to claim 1 , wherein the Ruthenium-Triphosphine-complex comprises a phosphororganic compound where two or all three phosphors have an aryl and/or heteroaryl moeity which is substituted in ortho and/or meta position to the phosphine bound thereto.4. The method according to claim 1 , wherein step a) is performed under acidic conditions.5. The method according to claim 1 , wherein step a) is performed under acidic conditions whereby the (initial) concentration of acid is ≧0.5 to ≦20 times the concentration of Ruthenium (in mol:mol).6. The method according to claim 5 , wherein step a) is performed under acidic conditions whereby the acid is selected out of the group comprising sulfonic acids claim 5 , especially methanesulfonic acid claim 5 , trifluormethansulfonic acid claim 5 , p-toluolsulfonic acid claim 5 , p-bromobenzosulfonic acid claim 5 , p-nitrobenzosulfonic acid claim 5 , sulfuric acid claim 5 , hydrochloric acid claim 5 , hydrofluoric acid claim 5 , trifluoracetic acid claim 5 , perchloric acid claim 5 , bis(trifluoromethane)sulfonimide or mixtures thereof7. The method according to claim claim 5 , wherein step a) is carried out at an initial hydrogen pressure of ≧1 bar.8. The method according to claim 1 , wherein step a) is carried out in a dipolar protic or aprotic solvent or in CO The present invention relates to a method for reducing organic molecules, especially by using Ruthenium-Triphosphine-complexes.In the prior art, e.g. ...

Synthesis of (S)-6-Hydroxytryptophan and Derivatives Thereof

The present invention relates to novel methods and compounds for synthesizing amanitin derivatives. The invention in particular relates to methods for synthesizing (S)-6-hydroxy-tryptophan derivatives which can be used as building blocks for synthesizing amanitin derivatives or amatoxin drug conjugates. The invention further relates to intermediate compounds of said synthesis pathways for use in amanitin derivative and amatoxin drug conjugate synthesis, and to the use of particular catalysts suited for mediating said synthesis pathways.

METHOD OF MAKING HYDROPROCESSING CATALYST

A chelated hydroprocessing catalyst exhibiting low moisture is obtained by heating an impregnated, calcined carrier to a temperature higher than 200° C. and less than a temperature and for a period of time that would cause substantial decomposition of the chelating agent. 1. A method for preparing a hydroprocessing catalyst comprising: (A) at least one calcined foraminous carrier having a water pore volume;', '(B) catalytically active metals useful in hydroprocessing hydrocarbons, said metals in the form of at least one component providing at least one metal from Group VIB of the periodic table and at least one component providing at least one metal from Group VIII of the periodic table;', '(C) at least one chelate;', '(D) water in a quantity sufficient to form a solution or dispersion comprising said catalytically active metals and said at least one chelate; and', '(E) optionally, at least one phosphorus-containing acidic component;, '(I) providing at least the following components(II) contacting said components (I)(A) with said solution or dispersion comprising (I)(B), (I)(C), (I)(D) and optionally (I)(E) for a time and at a temperature sufficient to form a mixture and to impregnate said carrier with a suitable amount of said components (I)(B) and (I)(C) and optionally (I)(E);(III) to the extent that the volume of said solution or dispersion equals or exceeds the water pore volume of said carrier separating said impregnated carrier from said excess solution or dispersion; and(IV) heating said impregnated carrier to a temperature higher than 200° C. and less than a temperature and for a period of time that would cause substantial decomposition of said at least one chelate.2. The method of claim 1 , wherein said at least one metal from Group VIB is selected from the group consisting of molybdenum and tungsten and wherein said at least one metal from Group VIII is selected from the group consisting of cobalt and nickel.3. (canceled)4. The method of wherein said ...

Catalyst for preparing 1,5-pentanediol via hydrogenolysis of tetrahydrofurfuryl alcohol, method and application thereof

The present invention provides a method for preparing 1,5-pentanediol via hydrogenolysis of tetrahydrofurfuryl alcohol. The catalyst used in the method is prepared by supporting a noble metal and a promoter on an organic polymer supporter or an inorganic hybrid material supporter, wherein the supporter is functionalized by a nitrogen-containing ligand. When the catalyst is used in the hydrogenolysis of tetrahydrofurfuryl alcohol to prepare 1,5-pentanediol, a good reaction activity and a high selectivity can be achieved. The promoter and the nitrogen-containing ligand in the supporter are bound to the catalyst through coordination, thereby the loss of the promoter is significantly decreased, and the catalyst has a particularly high stability. The lifetime investigation of the catalyst, which has been reused many times or used continuously for a long term, suggests that the catalyst has no obvious change in performance, thus reducing the overall process production cost.

ENANTIOSELECTIVE HYDROGENATION OF 4-SUBSTITUTED 1,2-DIHYDROQUINOLINES IN PRESENCE OF A CHIRAL IRIDIUM CATALYST

The invention relates to a process for preparing optically active 4-substituted 1,2,3,4-tetrahydroquinolines comprising enantioselective hydrogenation of the corresponding 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium (P,N)-ligand catalyst. 2: The process according to claim 1 , wherein{'sup': '1', 'sub': 1', '6', '6', '14', '1', '4, 'claim-text': {'sub': 6', '14', '6', '14', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4, 'wherein C-C-aryl in the C-C-aryl-C-C-alkyl moiety is unsubstituted or substituted by one to five substituents selected from the group consisting of halogen, C-C-alkyl, C-C-haloalkyl, C-C-alkoxy and C-C-haloalkoxy'}, 'Ris C-C-alkyl or C-C-aryl-C-C-alkyl,'}{'sup': 2', '3, 'sub': 1', '4, 'Rand Rare the same and are selected from C-C-alkyl,'}{'sup': '4', 'sub': 1', '4', '1', '4', '1', '4', '1', '4, 'Ris C-C-alkyl, C-C-haloalkyl, C-C-alkoxy, C-C-haloalkoxy, phenyl or benzyl,'}n is 0, 1 or 2, and{'sup': '5', 'sub': 1', '6', '1', '6, 'each substituent R, if present, is independently selected from the group consisting of halogen, C-C-alkyl and C-C-haloalkyl.'}3: The process according to claim 1 , wherein{'sup': '1', 'Ris methyl, ethyl or n-propyl,'}{'sup': 2', '3, 'Rand Rare methyl,'}{'sup': '4', 'sub': 1', '4, 'Ris C-C-alkyl,'}n is 0, 1 or 2, and{'sup': '5', 'sub': 1', '6, 'each substituent R, if present, is independently selected from the group consisting of halogen and C-C-alkyl.'}6: The process according to claim 1 , wherein the hydrogenation is conducted using hydrogen gas at a pressure of from 1 to 300 bar.7: The process according to claim 1 , wherein the amount of iridium catalyst used is within the range of from 0.001 mol % to 5 mol % claim 1 , based on the amount of the compound of the formula (II).8: The process according to claim 1 , wherein the hydrogenation is conducted at a temperature within the range of from 20° C. to 130° C.9: The process according to claim 1 , wherein the hydrogenation is conducted in presence of a ...

High Density Cyclic Fuels Derived From Linear Sesquiterpenes

A method to generate cyclic hydrocarbons from farnesene to increase both the density and net heat of combustion of the product fuels. The high density hydrocarbons produced by this method have applications for missile, UAV, jet, and diesel propulsion.

Mesoporous cobalt-metal oxide catalyst for fischer-tropsch synthesis reactions and a preparing method thereof

The present invention relates to a mesoporous cobalt-metal oxide catalyst for the Fischer-Tropsch synthesis and a method of preparing the same. The mesoporous cobalt-metal oxide catalyst for the Fischer-Tropsch synthesis of the present invention can very stably maintain the mesoporous structure even under a H 2 -rich high-temperature reduction condition and under a reaction condition of the low-temperature Fischer-Tropsch synthesis, easily transport reactants to the active site of the catalyst due to structural stability, and facilitate the release of heavier hydrocarbon products after production thereof. Additionally, unlike the conventional cobalt-based catalysts which are prepared by adding various co-catalysts for the purpose of improving reducibility, activity, selectivity and increasing thermal stability, etc., the mesoporous cobalt-metal oxide catalyst for the Fischer-Tropsch synthesis can constantly maintain conversion and selectivity at high levels without further requiring co-catalysts and thus it can be very effectively used for the Fischer-Tropsch synthesis.

NOVEL CHIRAL NITROGEN-PHOSPHORUS LIGANDS AND THEIR USE FOR ASYMMETRIC HYDROGENATION OF ALKENES

The invention relates to a series of novel chiral nitrogen-phosphorus ligands of formulae (Ia) and (Ib): 2. The compound according to claim 1 , wherein X is O.3. The compound according to claim 1 , wherein X is S.4. The compound according to claim 1 , wherein X is NR.5. The compound according to claim 1 , wherein Ris —(C-C)alkyl selected from —CH claim 1 , —CHCH claim 1 , —CH(CH) claim 1 , —C(CH) claim 1 , —C(CHCH) claim 1 , and —C(CHCH)(CH).6. The compound according to claim 1 , wherein Ris —(C-C)carbocyclyl selected from cyclopentyl claim 1 , cyclohexyl claim 1 , and 1-adamantyl.7. The compound according to claim 1 , wherein Ris —(C-C)aryl selected from phenyl claim 1 , ortho-tolyl claim 1 , para-tolyl claim 1 , 3 claim 1 ,5-dimethylphenyl claim 1 , 3 claim 1 ,5-di-t-butylphenyl claim 1 , 3 claim 1 ,5-di-CF-phenyl claim 1 , ortho-CF-phenyl claim 1 , ortho-anisyl claim 1 , and naphthyl.8. The compound according to claim 1 , wherein Ris H claim 1 , —CHor —OCH.9. The compound according to claim 1 , wherein Ris phenyl claim 1 , naphthyl or anthracene claim 1 , each optionally substituted with 1 to 3 substituents independently selected from —O(C-C)alkyl claim 1 , —(C-C)alkyl claim 1 , and —CF.10. The compound according to claim 1 , wherein Ris —(C-C)alkyl substituted with 1 to 3 (5- to 6-membered)heteroaryl; wherein the (5- to 6-membered)heteroaryl ring is optionally substituted with 1 to 3 Rsubstituents independently selected from —O(C-C)alkyl claim 1 , —(C-C)alkyl claim 1 , phenyl and —CF.11. The compound according to claim 10 , wherein Ris —CH(chiral oxazoline) or —CH(ortho-substituted pyridine) claim 10 , each optionally substituted with 1 to 3 Rsubstituents independently selected from —O(C-C)alkyl claim 10 , —(C-C)alkyl claim 10 , phenyl and —CF.12. The compound according to claim 1 , wherein Rortho-substituted pyridine optionally substituted with 1 to 3 Rsubstituents independently selected from —O(C-C)alkyl claim 1 , —(C-C)alkyl claim 1 , phenyl and —CF.14. The ...

INTEGRATED CAPTURE AND CONVERSION OF CO2 TO METHANOL OR METHANOL AND GLYCOL

A process for producing methanol includes combining a hydrogenation catalyst, hydrogen, and COwith a condensed phase solution comprising an amine under conditions effective to form methanol and water. A process for coproduction of methanol and a glycol includes combining an epoxide, a hydrogenation catalyst, hydrogen, and COwith a condensed phase solution comprising an amine under conditions effective to form methanol and a glycol. 1. A process , comprising:{'sub': 2', '2, 'producing methanol and a glycol by combining an epoxide, a hydrogenation catalyst, hydrogen, and COwith a condensed phase comprising an amine under conditions effective to provide a reaction between the epoxide, hydrogen, and COto form methanol and the glycol, wherein at least 10 mol % of the epoxide is consumed in the reaction.'}2. The process of claim 1 , wherein the condensed phase is a condensed phase solution further comprising the CO.3. The process of claim 2 , further comprising preparing the condensed phase solution by contacting a gas stream comprising COwith an amine-containing solvent or solution prior to combining the epoxide claim 2 , the hydrogenation catalyst claim 2 , and the hydrogen with the condensed phase solution.4. The process of claim 3 , wherein contacting the gas stream with the amine-containing solvent or solution is performed:(i) at a temperature T′ within a range of from 20° C. to 60° C.; or(ii) at an initial pressure P′ within a range of from 0.1 MPa to 5 MPa; or(iii) both (i) and (ii).5. The process of claim 1 , wherein the conditions effective to form methanol and the glycol comprise:{'sub': 'MG', '(i) a temperature Twithin a range of from 50° C. to 170° C.; or'}{'sub': 'MG', '(ii) an initial pressure Pwithin a range of from 3 MPa to 10 MPa; or'}{'sub': 'MG', '(iii) a time twithin a range of from 3 seconds to 36 hours; or'}(iv) any combination of (i), (ii), and (iii).6. The process of claim 1 , further comprising:{'sub': '2', '(i) combining the epoxide, the CO, and ...

Mononuclear iron complex and organic synthesis reaction using same

Provided is a mononuclear iron complex that comprises an iron-silicon bond that is represented by formula (1) and that exhibits excellent catalyst activity in each of a hydrosilylation reaction, a hydrogenation reaction, and reduction of a carbonyl compound. In formula (1), R 1 -R 6 either independently represent an alkyl group, an aryl group, an aralkyl group or the like that may be substituted with a hydrogen atom or X, or represent a crosslinking substituent in which at least one pair comprising one of R 1 -R 3 and one of R 4 -R 6 is combined. X represents a halogen atom, an organoxy group, or the like. L represents a two-electron ligand other than CO. When a plurality of L are present, the plurality of L may be the same as or different from each other. When two L are present, the two L may be bonded to each other. n and m independently represent an integer of 1 to 3 with the stipulation that n+m equals 3 or 4.

MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME

Provided is a mononuclear ruthenium complex that comprises a ruthenium-silicon bond that is represented by formula (1) and that exhibits excellent catalyst activity in each of a hydrosilylation reaction, a hydrogenation reaction, and reduction of a carbonyl compound. 2. The mononuclear ruthenium complex of wherein L is at least one two-electron ligand selected from the group consisting of molecular hydrogen claim 1 , amine claim 1 , imine claim 1 , nitrogen-containing heterocycle claim 1 , arsine claim 1 , alcohol claim 1 , thiol claim 1 , ether claim 1 , sulfide claim 1 , nitrile claim 1 , isonitrile claim 1 , aldehyde claim 1 , ketone claim 1 , C-Calkene claim 1 , C-Calkyne claim 1 , and triorganohydrosilane.3. The mononuclear ruthenium complex of or wherein n and m each are 2 claim 1 , and L is at least one ligand selected from sulfide claim 1 , thiol claim 1 , and triorganohydrosilane claim 1 , with the proviso that two L's may bond together.4. The mononuclear ruthenium complex of wherein Rto Rare each independently an alkyl claim 3 , aryl or aralkyl group which may be substituted with X which is as defined above claim 3 ,{'sup': 7', '8', '9', '10', '11', '12', '7', '12, "L's are triorganohydrosilanes represented by H—SiRRRand H—SiRRRwherein Rto Rare each independently an alkyl, aryl or aralkyl group which may be substituted with X which is as defined above,"}{'sup': 1', '3', '4', '6', '7', '9', '10', '12', '4', '6', '7', '9, 'at least one pair of any one of Rto Rand any one of Rto Ror any one of Rto R, or at least one pair of any one of Rto Rand any one of Rto Ror any one of Rto Rmay bond together to form a crosslinking substituent, or'}{'sup': 1', '3', '4', '6', '7', '9', '10', '12', '4', '6', '7', '9, 'at least one pair of any one of Rto Rand any one of Rto Ror any one of Rto Rmay bond together to form a crosslinking substituent, and at least one pair of any one of Rto Rand any one of Rto Ror any one of Rto Rmay bond together to form a crosslinking ...

Metallorganocatalysis For Asymmetric Transformations

A ligand having the structure or its enantiomer; (I) wherein: each one of R a , R b , R c and R d is selected from alkyl, cycloalkyl, and aryl; the bridge group is selected from CH 2 NH; *CH(CH 3 )NH(C*,R); and the organocatalyst is an organic molecule catalyst covalently bound to the bridge group. Also, a catalyst having the structure or its enantiomer: (II) wherein: each one of R a , R b , R c and R d is selected from alkyl, cycloalkyl, and aryl; the bridge group is selected from CH 2 NH; *CH(CH 3 )NH(C*,R); and *CH(CH 3 )NH(C*,S); the organocatalyst is an organic molecule catalyst covalently bound to the bridge group; and M is selected from the group consisting of Rh, Pd, Cu, Ru, Ir, Ag, Au, Zn, Ni, Co, and Fe.

P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS

Novel P-chirogenic organophosphorus compounds of general formula (I), a process for the synthesis of the compounds of formula (I), and intermediate products of general formulae (II), (III) and (IV), as shown below, are involved in the synthesis of compounds (I). 2. The process according to claim 1 , wherein the electrophile is selected from the group consisting of boronate reagents claim 1 , aldehydes claim 1 , ketones claim 1 , acyl chlorides claim 1 , halosilanes claim 1 , haloalkanes claim 1 , and Michael acceptors such as α claim 1 ,β-insaturated ester claim 1 , α claim 1 ,β-insaturated ketones claim 1 , and α claim 1 ,β-insaturated phosphine derivatives.3. The process according to claim 1 , wherein the oxidative reagent is selected from the group consisting of transition metal salts and transition metal complexes claim 1 , wherein the metal is selected from the group comprising iron claim 1 , copper.4. The process according to claim 1 , wherein compound (VII) is chiral. The present invention relates to novel P-chirogenic organophosphorus compounds of general formula (I). The present invention also provides a process for the synthesis of said compounds of formula (I). The present invention also relates to intermediate products of general formulae (II), (III) and (IV), as shown below, which are involved in the synthesis of compounds (I).Compounds of general formula (I) may useful as agrochemical and therapeutic substances, or as reagents or intermediates for fine chemistry.Further, the invention relates to metal complexes comprising compounds (I) as ligands. The novel compounds and complexes of the present invention are useful in asymmetric catalysis by transition metal complexes or organocatalysis, especially for asymmetric hydrogenation or allylation.During the past decades, asymmetric organocatalysis and organometallic catalysis made a breakthrough and became methodologies of choice for the synthesis of chiral substances on laboratory as well as on industrial ...

PHENANTHROLINE BASED PINCER COMPLEXES USEFUL AS CATALYSTS FOR THE PREPARATION OF METHANOL FROM CARBONDIOXIDE

The present invention relates to a novel phenonthroline based pincer complexes and process for preparation thereof. The present invention also provides a one pot process for the conversion of carbon dioxide to methanol in the presence of a molecularly defined pincer-type single-site Ru-catalyst and secondary amine. Further the present invention provides the use of phenonthroline based pincer complexes for the esterification of alcohols and hydrogenation of esters under mild conditions. 3. The phenanthroline based pincer complexes of formula (I) as claimed in claim 1 , wherein the said catalyst is used for hydrogenation of lactones to diols and esters to alcohols4. The phenanthroline based pincer complexes of formula (I) as claimed in claim 1 , wherein the said catalyst is used for dehydrogenation of diols to lactones claim 1 , alcohol to esters and secondary alcohols to ketones.6. The process as claimed in claim 8 , wherein solvent used in step (a) is selected from hexane claim 8 , heptane claim 8 , tetrahydrofuran (THF) claim 8 , diethyl ether claim 8 , toluene claim 8 , and etheylbenzene.8. The process as claimed in claim 1 , wherein catalyst of formula 1 used in step (i) is selected from HCl(CO)Ru(Phen-(Bu)PNN) (3); H(CO)Ru-(Phen-(Bu)PNN) (4); H(CO)Ru(η1BH4)(Phen-(tBu)PNN) (5a); HCl(CO)Ru(BPy-PNN); [H(CO)Ru(BPy-PNN)]; and H(CO) Ru(Py-PNN)].9. The process as claimed in claim 7 , wherein said steps (ii) and (vi) are absent when [H(CO)Ru(BPy-PNN)] catalyst is used. The present invention relates to phenonthroline based pincer complex of formula (I) and process for preparation thereof. Particularly the present invention relates to use of phenonthroline based pincer complex of formula (I) as catalyst for the esterification of alcohols and hydrogenation of esters including lactones under mild conditions. More particularly the present invention relates to a one pot process for the conversion of carbon dioxide to methanol in the presence of a pincer based catalyst and a ...

HETEROGENEOUS METAL-FREE CATALYST

The inventive concepts disclosed and/or claimed herein relate generally to catalysts and, more particularly, but not by way of limitation, to a heterogeneous, metal-free hydrogenation catalyst containing frustrated Lewis pairs. In one non-limiting embodiment, the heterogeneous, metal-free catalyst comprises hexagonal boron nitride (h-BN) having frustrated Lewis pairs therein. 1. A heterogeneous hydrogenation catalyst , comprising:a solid surface substantially free of metals, the solid surface having at least one Lewis acid site and at least one Lewis base site; andat least one defect frustrating at least one pair of Lewis acid and Lewis base site sites, wherein the at least one frustrated pair of Lewis acid and Lewis base sites is catalytically active.2. A heterogeneous hydrogenation catalyst , comprising:a solid surface having non-metallic Lewis acid moieties and non-metallic Lewis base moieties spaced a distance apart from one another such that (a) catalytic activity is present therebetween and (b) the formation of an acid-base adduct is prevented.3. The heterogeneous hydrogenation catalyst of claim 2 , wherein the Lewis acid moieties are selected from the group consisting of Group 13 elements in a trigonal planar configuration claim 2 , halides of Group 15 elements claim 2 , electron poor π-systems claim 2 , and combinations thereof.4. The heterogeneous hydrogenation catalyst of claim 2 , wherein the Lewis base moieties are selected from the group consisting of simple anions claim 2 , lone-pair-containing species claim 2 , complex anions claim 2 , electron rich π-systems claim 2 , and combinations thereof.5. The heterogeneous hydrogenation catalyst of claim 2 , wherein the Lewis acid moieties are selected from the group consisting of Group 13 elements in a trigonal planar configuration claim 2 , halides of Group 15 elements claim 2 , electron poor π-systems claim 2 , and combinations thereof claim 2 , and the Lewis base moieties are selected from the group ...

CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER

This invention relates to novel catalyst compositions based on Ruthenium- or Osmium-based complex catalysts of the Grubbs-Hoveyda, Grela or Zhan type and specific co-catalysts comprising at least one vinyl group, pref. ethyl vinyl ether, and to a process for selectively hydrogenating nitrile rubbers in the presence of such catalyst compositions, preferably with a preceding metathesis step using the same complex catalyst as in the hydrogenation step. 2. The catalyst composition according to wherein the co-catalyst has the general formula (1){'br': None, 'sub': '2', 'CH═CRR′\u2003\u2003(1)'}in which R and R′ are identical or different and shall meanhydrogen or{'sup': 1', '1', '2', '2', '2', '3', '4, 'sub': 2', '2', 'n', 'm', '2', 'n', 'm', '2', '2', 'p', '2, 'claim-text': wherein', {'sup': '2', 'X is identical or different and means oxygen (O) or NR'}, {'sup': '2', 'Rare identical or different and represent H, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, or heteroaryl,'}, {'sup': '3', 'sub': 1', '8', '2', 'n', '2, 'Rare identical or different and represent C-Calkyl or —(CH)—O—CH═CH,'}, {'sup': '4', 'sub': 2', 'p', '2, 'Rrepresents (CH)—O—CH═CH,'}, 'n is in the range of from 1 to 5,', 'm is in the range of from 1 to 10,', 'p is in the range of from 0 to 5, or', {'sup': 1', '1', '2', '2, 'sub': 2', 'q, 'where in the alternative, if R and R′ both represent a group OR, both Rmay be linked to each other and together represent a divalent group —(C(R))— with q being 2, 3 or 4 and Rbeing identical or different and having the above defined meanings, or'}], 'ORwherein Rshall mean alkyl, cycloalkyl, alkenyl, alkynyl, aryl, or heteroaryl, C(═O)(R), —C(═O)N(R), —[(CH)—X]R, —[(CH)—X]—CH═CH, or —(CH)—C(R)R'}{'sup': 5', '5', '5, 'sub': '2', 'SR, SOR, SOR'}{'sup': '5', 'wherein Rrepresents alkyl, cycloalkyl, alkenyl, alkynyl, aryl, or heteroaryl, or'}{'sup': 6', '7', '6', '7, 'N(RR), P(RR)'}{'sup': 6', '7', '2, 'wherein Rand Rare identical or different and shall mean alkyl, cycloalkyl, ...

Catalyst for recycling a plastic

A catalyst for recycling a plastic chosen from polyethylene, polypropylene, polystyrene, and combinations thereof includes a porous support having an exterior surface and at least one pore therein, a depolymerization catalyst component comprising a metallocene catalyst disposed on the exterior surface of the porous support, and a reducing catalyst component disposed in the at least one pore. The exterior surface of the porous support comprises less than 10 parts by weight of the reducing catalyst component based on 100 parts by weight of the depolymerization catalyst component as determined using Energy Dispersive X-Ray Spectroscopy (EDS). Moreover, the reducing catalyst component comprises a transition metal selected from the group of iron, nickel, palladium, platinum, and combinations thereof. The at least one pore in the porous support has an average pore size of 10 Angstroms.

TRANSFER HYDROGENATION OF CYCLOPAMINE ANALOGS

Provided herein is a process for the transfer-hydrogenation of ketone analogs of members of the jervine type of alkaloids, such as cyclopamine. Also provided herein are novel ruthenium transfer-hydrogenation catalysts. 3. The process of wherein the ring carbon atom that is directly attached to the hydroxyl group on the compound of formula (II-AA) has an (S) stereochemical configuration and Ris hydrogen in the β-position.4. The process of claim 1 , wherein the ruthenium transfer-hydrogenation catalyst comprises an amino alcohol ligand.5. The process of claim 4 , wherein the amino alcohol ligand is achiral.7. The process of claim 6 , wherein Rand Rare both —CHand Ris —CHCH.8. The process of claim 1 , wherein the ruthenium transfer-hydrogenation catalyst comprises an optionally substituted benzene ligand.9. The process according to claim 8 , wherein the optionally substituted benzene ligand is selected from benzene claim 8 , mesitylene claim 8 , p-cymene claim 8 , and hexamethylbenzene.10. The process according to claim 9 , wherein the ruthenium transfer-hydrogenation catalyst is generated from (hexamethylbenzene)ruthenium chloride dimer and an achiral amino alcohol.14. The process according to claim 13 , wherein Xis chloro.17. The process of claim 16 , wherein Rand Rare each methyl claim 16 , Ris ethyl claim 16 , each of R claim 16 , R claim 16 , R claim 16 , R claim 16 , R claim 16 , and Ris methyl claim 16 , and Xis Cl.18. The process of claim 1 , wherein the hydrogen donor is an organic alcohol.19. The process of claim 18 , wherein the reducing is carried out in an ether solvent.20. The process of claim 19 , wherein the reducing is carried out at a temperature of about 10° C. to about 40° C.21. The process of claim 19 , wherein the reducing is carried out in the presence of base. This application is a continuation of U.S. patent application Ser. No. 13/232,851, filed Sep. 14, 2011, now allowed, which claims the benefit of U.S. Provisional Patent Application No. 61/ ...

Metal Supported Powder Catalyst Matrix and Processes for Multiphase Chemical Reactions

A catalytic membrane composite that includes porous supported catalyst particles durably enmeshed in a porous fibrillated polymer membrane is provided. The porous fibrillated polymer membrane may be manipulated to take the form of a tube, disc, or diced tape and used in multiphase reaction systems. The supported catalyst particles are composed of at least one finely divided metal catalyst dispersed on a porous support substrate. High catalytic activity is gained by the effective fine dispersion of the finely divided metal catalyst such that the metal catalyst covers the support substrate and/or is interspersed in the pores of the support substrate. In some embodiments, the catalytic membrane composite may be introduced to a stirred tank autoclave reactor system, a continuous flow reactor system, or a Parr Shaker reaction system and used to effect the catalytic reaction. 1. A continuous flow reaction system for multiphase reactions having at least three phases , said reaction system comprising:a catalytic article comprising a porous fibrillated polymer membrane that includes supported catalyst particles durably enmeshed within the porous fibrillated polymer membrane;a liquid phase comprising at least one liquid phase reactant;a gas phase comprising at least one gas phase reactant; anda reaction vessel configured for continuous flow of the liquid phase reactant and the gas phase reactant across and through the catalytic article,wherein the catalytic article is in the form of a tube or a plurality of tubes bundled in a tubular array.2. The reaction system of claim 1 , wherein the catalytic article is not configured as a contactor.3. The reaction system of claim 1 , wherein the reaction system is configured for hydrogenation.4. The reaction system of claim 1 , wherein the porous fibrillated polymer membrane is insoluble to reactants and products in the multiphase chemical reaction.5. The reaction system of claim 1 , wherein the porous fibrillated polymer membrane ...

METHODS FOR RECOVERING AND REUSING SELECTIVE HOMOGENEOUS HYDROGENATION CATALYST

The present invention pertains to a method for recovering a selective homogeneous hydrogenation catalyst and a method for reusing the recovered selective homogeneous hydrogenation catalyst. The method for recovering a selective homogeneous hydrogenation catalyst comprises: a step for synthesizing cyclododecene by selectively hydrogenating a first reaction solution containing cyclododecatriene, triphenylphosphine, formaldehyde, and ruthenium chloride, wherein a selective homogeneous hydrogenation catalyst is prepared during the selective hydrogenation reaction from the triphenylphosphine, formaldehyde, and ruthenium chloride to synthesize the cyclododecene; and a step for distilling and separating unreacted cyclododecatriene and cyclododecadiene, as well as the product cyclododecene, from a second reaction solution in which the cyclododecene synthesis has been completed, and recovering the selective homogeneous hydrogenation catalyst. 1. A method for recovering a selective homogeneous hydrogenation catalyst , comprising:a step of synthesizing cyclododecene by selectively hydrogenating a first reaction solution containing cyclododecatriene, triphenylphosphine, formaldehyde, and ruthenium chloride, the cyclododecene being synthesized by preparation of a selective homogeneous hydrogenation catalyst from the triphenylphosphine, the formaldehyde, and the ruthenium chloride during the selective hydrogenation; anda step of distilling and separating unreacted cyclododecatriene and cyclododecadiene, and the cyclododecene that is a product from a second reaction solution in which the cyclododecene synthesis is completed, and recovering the selective homogeneous hydrogenation catalyst.2. The method of claim 1 , wherein the distillation and separation is performed at a temperature of 100 to 200° C. and a pressure of 0.5 bar or less.3. The method of claim 1 , wherein the recovering of the selective homogeneous hydrogenation catalyst is performed at a temperature of 10 to 30° C. ...

MONOCARBONYL RUTHENIUM AND OSMIUM CATALYSTS

The invention relates to monocarbonyl complexes of ruthenium and osmium with bi- and tridentate nitrogen and phosphine ligands. The invention relates to methods for preparing these complexes and the use of these complexes, isolated or prepared in situ, as catalysts for reduction reactions of ketones and aldehydes both via transfer hydrogenation or hydrogenation with hydrogen. 3. The complex of claim 1 , of formula (VII):{'br': None, '[MX(CO)(NN)(PP)]W \u2003\u2003(VII)'}{'sub': 2', '2', '2', '2', '2, 'provided that when X is Cl or H, (NN) is not ethylenediamine or 2-(aminomethyl)pyridine and the diphosphine (PP) is not PhP(CHCHCH)PPh.'}4. The complex of claim 1 , of formula (VIII):{'br': None, 'MXY(CO)(HCNN)(P) \u2003\u2003(VIII).'}5. The complex of claim 1 , of formula (IX):{'br': None, 'MX(CO)(CNN)(P) \u2003\u2003(IX).'}7. The complex of claim 1 , of formula (XI):{'br': None, 'MX(CO)(CP)(HCP) \u2003\u2003(XI)'}{'sup': 23', '21', '22, 'sub': '3', 'provided that when X is Cl and Ris —CH, R-Rare not phenyl.'}8. The complex of claim 1 , of formula (XII):{'br': None, 'MXY(CO)(PP)(P) \u2003\u2003(XII).'}9. The complex of claim 1 , of formula (XIII):{'br': None, 'MXY(CO)(HCN)(PP) \u2003\u2003(XIII).'}10. The complex of claim 1 , of formula (XIV):{'br': None, 'MXY(CO)(PNN) \u2003\u2003(XIV).'}11. The complex of claim 1 , wherein X and Y are the same and are Cl claim 1 , H claim 1 , a C1-C20 alkoxide claim 1 , or a C1-C20 carboxylate.18. A process for preparing a complex of formula (XII) of claim 8 , comprising reacting a compound of formula MXY(CO)(PPh) claim 8 , or formula MXY(CO)(PPh)(dmf) claim 8 , wherein (dmf) is dimethylformamide claim 8 , with a phosphine (P) that is:{'sup': 16', '17', '18', '16', '18, 'a phosphine of formula PRRR, wherein R-Rare each, independently, H, a C1-C20 aliphatic group, or a C5-C20 aromatic group; or'}an optically active phosphine that is (S)-neomenthyldiphenylphosphine or (R)-(+)-2-(diphenylphosphino)-2′-methoxy-1,1′-binaphthyl;or a ...

HIGHLY EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN VIA RHODIUM CATALYZED ASYMMETRIC HYDROGENATION

The present invention provides highly efficient process for the preparation of enantiomerically enriched Sitagliptin of Formula (Ia). More particularly, a direct rhodium catalyzed asymmetric hydrogenation in the presence of bis-phosphine chiral ligand has been developed to yield enantiopure Sitagliptin product with the highest enantiomeric excess of 85-99.9%. 14-. (canceled)6. The process of claim 5 , wherein the rhodium catalyst is [Rh(COD)OTf].7. The process of claim 6 , wherein the additive is selected from the group consisting of salicylic acid claim 6 , acetic acid claim 6 , ammonium chloride claim 6 , phosphoric acid claim 6 , ammonium salicylate claim 6 , tetramethyl ammonium iodide claim 6 , tetraethyl ammonium iodide claim 6 , tetra butyl ammonium bromide claim 6 , butyl phosphoric acid claim 6 , dibutyl phosphate claim 6 , and tributyl phosphate.8. The process of claim 6 , wherein the solvent is selected from the group consisting of methanol claim 6 , dichloromethane claim 6 , tetrahydrofuran claim 6 , trifluoroethanol claim 6 , toluene claim 6 , 1 claim 6 ,4-dioxane claim 6 , and ethyl acetate. This application is a national-stage application under 35 U.S.C. § 371 of International Application No. PCT/IN2019/050896, filed Dec. 9, 2019, which International Application claims benefit of priority to Indian Application No. 201811046767, filed Dec. 11, 2018.The present disclosure provides highly efficient process for the preparation of enantiomerically enriched Sitagliptin. More particularly, a direct rhodium catalyzed asymmetric hydrogenation in the presence of bis-phosphine chiral ligand has been developed to yield enantiopure Sitagliptin product with the highest enantiomeric excess of 85-99.9%.Beta amino acids and its derivatives have lot of medicinal significance. Beta amino acids are also present in peptides and different heterocycles. In beta amino acids, the amino group is linked to the beta carbon. Different free forms and derivatives of beta amino acid ...

Method for Producing Alpha, Alpha-Difluoroacetaldehyde

Disclosed is an industrial method for efficient production of an α,α-difluoroaldehyde compound, which includes reaction of an α,α-difluoroacetate with hydrogen gas (H2) in the presence of a ruthenium catalyst and a base. By the adoption of specific reaction conditions (catalyst, base, pressure etc.), it is possible to produce the target α,α-difluoroaldehyde compound with a high conversion rate and high selectivity.

Metal Supported Powder Catalyst Matrix And Processes For Multiphase Chemical Reactions

A catalytic membrane composite that includes porous supported catalyst particles durably enmeshed in a porous fibrillated polymer membrane is provided. The porous fibrillated polymer membrane may be manipulated to take the form of a tube, disc, or diced tape and used in multiphase reaction systems. The supported catalyst particles are composed of at least one finely divided metal catalyst dispersed on a porous support substrate. High catalytic activity is gained by the effective fine dispersion of the finely divided metal catalyst such that the metal catalyst covers the support substrate and/or is interspersed in the pores of the support substrate. In some embodiments, the catalytic membrane composite may be introduced to a stirred tank autoclave reactor system, a continuous flow reactor system, or a Parr Shaker reaction system and used to effect the catalytic reaction. 1. A reaction system for multiphase reactions having at least three phases , said reaction system comprising:a stirred tank reaction vessel comprising a rotatable impeller shaft having thereon at least one impeller blade, said rotatable impeller shaft being rotatably affixed to a catalytic article, said catalytic article comprising a porous fibrillated polymer membrane that includes supported catalyst particles durably enmeshed within the porous fibrillated polymer membrane;a liquid phase comprising at least one liquid phase reactant; anda gas phase comprising at least one gas phase reactant,wherein the porous fibrillated polymer membrane is in the form of an immobilized catalyst disc or disc stack.2. The reaction system of claim 1 , wherein reaction system is configured for hydrogenation.3. The reaction system of claim 1 , wherein the catalytic article is not configured as a contactor.4. The reaction system of claim 1 , wherein the impeller blade is pitched.5. The reaction system of claim 1 , wherein the disc stack comprises a plurality of immobilized catalyst discs with intervening spacers ...

POLYMER NANOPARTICLES

Polymer nanoparticles, including Janus nanoparticles, and methods of making them are described. 1. A method of forming a multi-faced polymer nanoparticle , comprisingdissolving a first polymer at a first concentration and a second polymer at a second concentration in a solvent to form a polymer solution,selecting a nonsolvent,selecting a mean nanoparticle diameter,selecting the first concentration and second concentration to achieve the selected moan nanoparticle diameter, andcontinuously mixing the polymer solution with the nonsolvent to flash precipitate the multi-faced polymer nanoparticle in a mixture of the solvent and the nonsolvent,wherein the first polymer is different from the second polymer and a first region, comprising the first polymer at a greater weight fraction than the second polymer, and', 'a second region, comprising the second polymer at a greater weight fraction than the first polymer,', 'the first region being in contact with the second region., 'wherein the multi-faced polymer nanoparticle comprises'}2. The method of claim 1 , wherein neither the polymer solution nor the nonsolvent comprise a stabilizer.3. The method of claim 1 , wherein the mixing of the polymer solution with the nonsolvent further comprises mixing with a collection solution.4. The method of claim 3 , wherein the collection solution comprises a stabilizer.5. The method of claim 4 , wherein the stabilizer is an amphiphilic surfactant molecule.6. The method of claim 4 , wherein the stabilizer is selected from the group consisting of sulfonated alkyl surfactants claim 4 , sodium dodecyl sulfate claim 4 , ethoxylated sulfonate surfactants claim 4 , cationic surfactants claim 4 , amine oxide surfactants claim 4 , zwitterionic surfactants claim 4 , amphoteric surfactants claim 4 , ethylene oxide surfactants based on alkyl ethers claim 4 , ethylene oxide surfactants based on nonylphenols claim 4 , surfactants based on sorbitan oleates claim 4 , glucose-based surfactants claim 4 , ...

RUTHENIUM-PHENOL CATALYSTS FOR TRANSFER HYDROGENATION REACTIONS

The present invention is directed towards a catalyst which is obtainable by contacting in situ a ruthenium precursor and a phenol derivative. Furthermore, the present invention is directed towards the use of said catalyst in transfer hydrogenation reactions. In particular, the present invention is directed to a method for preparing menthone starting from isopulegol. 115-. (canceled)17. The ruthenium catalyst of claim 16 , wherein the phenol derivative is of formula (Ic) claim 16 , and{'sup': 1', '2', '3', '4, 'sub': 1', '10', '3', '10, 'R, R, R, Rindependently are hydrogen, linear C-C-alkyl, or branched C-C-alkyl, or'}{'sup': 3', '4, 'R, Rtogether with the carbon atoms to which they are bound form an anellated aromatic ring;'}{'sup': 6', '7', '8', '9, 'sub': 1', '10', '3', '10, 'R, R, R, Rindependently are hydrogen, linear C-C-alkyl, or branched C-C-alkyl, or'}{'sup': 6', '7, 'R, Rtogether with the carbon atoms to which they are bound form an anellated aromatic ring;'}{'sup': '10', 'Ris hydrogen or hydroxy, and'}X is a chemical bond or alkylene.18. The ruthenium catalyst of claim 16 , wherein the ruthenium precursor which has labile ligands is represented by the formula (II){'br': None, 'sub': m', 'n, '[RuL]\u2003\u2003(II)'}whereinRu is in the oxidation state (+II), (+III) or (+IV);each L independently is hydride, halide, alkyl, aliphatic olefins optionally substituted by 1, 2 or 3 substituents which are independently selected from the group consisting of halogen, alkyl, substituted alkyl, cycloalkyl, aryl, and OH, cyclic olefins optionally substituted by 1, 2 or 3 substituents which are independently selected from the group consisting of halogen, alkyl, substituted alkyl, cycloalkyl, aryl, and OH, —CO, 1,3-dialkyldionate, alkanoate, or aryl optionally substituted by 1, 2, 3, 4 or 5 substituents, in particular 1, 2, 3 substituents which are independently selected from the group consisting of halogen, alkyl, substituted alkyl, alkoxy and OH;m is an integer in a ...

SYNTHESIS METHOD AND SYNTHESIS DEVICE FOR CYCLODODECENE

A synthesis method and a synthesis device of cyclododecene according to the present invention have a high conversion rate of cyclododecatriene which is a reactant and a high selectivity of cyclododecene which is a required product, and even so, have an effect of significantly decreasing a reaction time. In addition, the method and the device have an excellent conversion rate of cyclododecatriene and an excellent selectivity of cyclododecene, while maintaining excellent reactivity without an organic solvent such as ethanol. Therefore, a volume of the reactor relative to an output of cyclododecene may be further decreased. Moreover, the method and the device may minimize costs for facilities and process, are practical, decrease a process time, and are industrially advantageous for mass production as compared with the conventional art. 1. A synthesis method of cyclododecene , the method comprising a hydrogenation process of subjecting cyclododecatriene to a partial hydrogenation reaction under a catalyst to synthesize cyclododecene ,wherein in the hydrogenation, cyclododecatriene and a hydrogen gas are reacted in a stirring tank reactor provided with a gas induction hollow-type agitator to synthesize cyclododecene.2. The synthesis method of cyclododecene of claim 1 , wherein in the hydrogenation claim 1 , the reaction is carried out by stirring the gas induction hollow-type agitator claim 1 , and the hydrogen gas is supplied to cyclododecatriene through a hollow portion of the gas induction hollow-type agitator.3. The synthesis method of cyclododecene of claim 2 , wherein the stirring tank reactor includes a reaction space formed inside claim 2 , and the reaction space includes a gaseous space formed in an upper portion and having a hydrogen gas and a liquid space formed in a lower portion and having a mixture including cyclododecatriene and the catalyst.4. The synthesis method of cyclododecene of claim 3 ,wherein the gas induction hollow-type agitator includes: an ...

Iron-catalyzed transfer hydrogenation of esters to alcohols

Iron-based homogeneous catalysts, supported by pincer ligands, are employed in the transfer hydrogenation of esters using C2-C12 alcohols as sacrificial hydrogen donors to produce corresponding alcohols from the esters. No external H2 pressure is required. The reaction can be carried out under ambient pressure.

SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS

A transfer hydrogenation process for forming vicinal diols by hydrogenating 1,2-dioxygenated organic compounds using alcohols as the reducing agent instead of the traditional Hgas. The transfer hydrogenation is carried out under milder conditions of temperature and pressure than is typical for ester hydrogenation with H. The milder conditions of operation provide benefits, such as lower operating and capital costs for industrial scale production as well as savings in product purification due to the avoidance of by-products from exposure of reaction mixtures and products to high temperatures. 4. The process according to claim 1 , wherein one or more of R claim 1 , R claim 1 , R claim 1 , and Rare substituted with one or more groups selected from ethers and amides.5. The process according to claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , and Rare each independently a methyl claim 1 , ethyl claim 1 , propyl claim 1 , isopropyl claim 1 , butyl claim 1 , pentyl claim 1 , isopentyl claim 1 , cyclopentyl claim 1 , hexyl claim 1 , cyclohexyl claim 1 , or phenyl group.6. The process according to claim 5 , wherein each of R claim 5 , R claim 5 , R claim 5 , and Ris isopropyl.7. The process according to claim 5 , wherein each of R claim 5 , R claim 5 , R claim 5 , and Ris phenyl.8. The process according to claim 1 , wherein each of Rand Ris —(CHCH)—.9. The process according to claim 1 , wherein E is phosphorus.10. The process according to claim 1 , wherein L is carbon monoxide claim 1 , a phosphine claim 1 , an amine claim 1 , a nitrile claim 1 , or an N-containing heterocyclic ligand.11. The process according to claim 2 , wherein Lis an ether claim 2 , an amide claim 2 , a nitrile claim 2 , or an N-containing heterocyclic ligand.12. The process according to claim 1 , wherein the contacting step is conducted at a temperature of 50 to 180° C.13. The process according to claim 1 , wherein the contacting step is conducted at a temperature of 75 to 100° C.14. The process ...

IRON-CATALYZED CROSS-COUPLING OF METHANOL WITH SECONDARY OR TERTIARY ALCOHOLS TO PRODUCE FORMATE ESTERS

A process for preparing a variety of secondary and tertiary alkyl formate esters via the coupling of methanol and secondary (or tertiary) alcohols. Iron-based catalysts, supported by pincer ligands, are employed to produce these formate esters in high yields and unprecedentedly high selectivities (>99%). Remarkably, the coupling strategy is also applicable to bulkier tertiary alcohols, which afford corresponding tertiary formate esters in moderately high yields and high selectivities. 4. The process according to claim 1 , wherein one or more of R claim 1 , R claim 1 , R claim 1 , and Rare substituted with one or more groups selected from ethers claim 1 , esters claim 1 , and amides.5. The process according to claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , and Rare each independently a methyl claim 1 , ethyl claim 1 , propyl claim 1 , isopropyl claim 1 , butyl claim 1 , pentyl claim 1 , isopentyl claim 1 , cyclopentyl claim 1 , hexyl claim 1 , cyclohexyl claim 1 , or phenyl group.6. The process according to claim 5 , wherein each of R claim 5 , R claim 5 , R claim 5 , and Ris isopropyl.7. The process according to claim 5 , wherein each of R claim 5 , R claim 5 , R claim 5 , and Ris phenyl.8. The process according to claim 1 , wherein each of Rand Ris —(CHCH)—.9. The process according to claim 1 , wherein E is phosphorus.10. The process according to claim 1 , wherein L is carbon monoxide claim 1 , a phosphine claim 1 , an amine claim 1 , a nitrile claim 1 , or an N-containing heterocyclic ligand.11. The process according to claim 2 , wherein Lis an ether claim 2 , an ester claim 2 , an amide claim 2 , a nitrile claim 2 , or an N-containing heterocyclic ligand.12. The process according to claim 1 , wherein the contacting step is conducted at a temperature of 40 to 160° C.13. The process according to claim 1 , wherein the contacting step is conducted in the presence of a solvent.14. The process according to claim 1 , wherein the contacting step is conducted in ...

PROCESS FOR THE DIASTEREOSELECTIVE PREPARATION OF RUTHENIUM COMPLEXES

The present invention relates to a process for the preparation of a compound of formula (I), wherein X is —CH—, —CH—CH—, —CH—CH—CH— or —CH—CH—CH—CH—; Yis —CH—; —CH2—CH— or —NH—; Yis NHR, or SH; wherein Ris hydrogen, C-Calkyl or phenyl; R—and R, independently from each other, represent aliphatic or aromatic groups; Rand R, independently from each other, represent aliphatic or aromatic groups; Rand Rare each hydrogen or represent together with the carbon atoms to which they are bonded, a phenyl ring; which process comprises reacting a compound of formula II [RuCI(R)n]m (II), wherein n is 1 and m is >1 which represents a polymeric structure if Ris a molecule containing two alkene or alkyne moieties coordinating in an hapto-2 coordination mode to the metal; or n is 4 and m is 1 if Ris a nitrogen, oxygen or sulfur containing molecule in which said nitrogen, oxygen or sulfur coordinate to the metal; in the presence of an inert solvent which boiling point is from 112° C. to 165° C. with a compound of formula (III), wherein R, R, Yand Yare as defmed under formula I, and a phosphane of formula IV R3R4P—X—PRR(iv), wherein R, R, R, Rand X are as defined under formula I. 2. A process according to for the preparation of a compound of formula I claim 1 , wherein{'sub': 2', '2', '2', '2, 'X is —CH—CH—CH—CH—.'}3. A process according to for the preparation of a compound of formula I claim 2 , wherein{'sub': '8', 'Ris cyclooctadiene or bicyclo[2.2.1]hepta-2,5-diene if n is 1 and m >1; or is dimethylsulfoxide if n is 4 and m is 1.'}4. A process according to for the preparation of a compound of formula I claim 2 , wherein{'sub': 1', '2', '3', '4, 'R, R, Rand Rare phenyl and'}{'sub': 5', '6, 'Rand Rare hydrogen or together represent with the carbon atoms to which they are bonded, a phenyl ring;'}{'sub': 1', '2, 'Yis —CH—, and'}{'sub': 2', '2, 'Yis NH.'}6. A process according to performed as a one pot procedure. The present invention relates to a process for the diastereoselective ...

Methods of Activating Metal Complexes for Catalysts

The present invention is directed to the activation of metal carbonyl clusters by an oxidative agent to prepare a stable metal cluster catalyst exhibiting catalytic rate enhancement. The activation comprises, for example, using oxygen for decarbonylation of carbonyl ligands and changing the oxidation state of the other ligands. In one aspect, treatment of the metal cluster catalyst under oxidative conditions in a flow reactor leads to removal of CO ligands and oxidation of bound calixarene phosphine ligands, and results in a stable activated open metal cluster that is more active for ethylene hydrogenation catalysis. The resulting metal cluster contains coordinatively unsaturated sites comprising carbonyl vacancies. In one aspect, the resulting activated open metal cluster can be used as a catalyst in a variety of chemical transformations.

RUTHENIUM-BASED TRIAZOLE CARBENE COMPLEXES

The present invention relates to novel ruthenium-based triazole carbene complexes comprising specific ligands, their preparation and their use as catalysts in hydrogenation processes. Such complex catalysts are inexpensive, thermally robust, gel formation inhibiting and olefin selective. 2. The catalyst according to claim 1 , wherein:{'sub': 6', '10', '6', '10', '2', '3', '3, 'sup': 3', '3', '3, 'R is independently of one another hydrogen, halogen, nitro, methyl, ethyl, n-propyl, isopropyl, n-butyl, iso-butyl, sec-butyl or tert-butyl, phenyl, or together with the carbon atoms to which they are bound form a C-C-cycloalkyl or C-C-aryl substituent, alkyl thiolate, aryl thiolate, B(R)or B(R), whereas Ris alkyl, aryl, alkoxy or aryloxy or CF,'}n is 0 to 4, preferably 0 to 2, more preferably 0 to 1{'sup': 1', '2, 'sub': '1', 'Rand Rare identical or different and are each methyl, ethyl, n-propyl, iso-propyl, n-butyl, iso-butyl, sec-butyl, tert-butyl or neopentyl, cyclohexyl, adamantyl, phenyl, C-methanesulphonate, p-toluenesulphonate, 2,4,6-trimethylphenyl (Mes) or 2,4,6-triisopropylphenyl (Trip),'}{'sub': 1', '30', '6', '24, 'X is hydride, halide pseudohalide, alkoxide, amide, triflate, phosphate, borate, straight-chain or branched C-C-alkyl or C-C-aryl, carboxylate, acetate, halogenated acetate, halogenated alkylsulfonate, tosylate or any weakly coordinating anionic ligands, and'}{'sup': 1', '2, 'sub': 1', '10', '3', '20', '3', '1', '10', '1', '10', '1', '10', '1', '10', '1', '10', '1', '10', '1', '10', '1', '10', '1', '10', '1', '5', '1', '5, 'Yand Yare identical or different and are each C-C-alkylphosphine or C-C-cycloalkylphosphine ligand, preferably tricyclohexylphosphine (PCy), a sulfonated C-C-alkylphosphine ligand, a C-C-alkylphosphinite ligand, a C-C-alkylphosphonite ligand, a C-C-alkyl phosphite ligand, a C-C-alkylarsine ligand, a C-C-alkylamine ligand, a substituted or not substituted pyridine ligand, a C-C-alkyl sulfoxide ligand, a C-C-alkyloxy ligand or a C-C ...

Ruthenium complex, method for producing same, and use of same

The present invention provides a novel ruthenium complex that is easy to produce and handle and that can be supplied relatively inexpensively, a method for producing this ruthenium complex, a method for producing alcohols and the like using this ruthenium complex as a catalyst, a method for producing carbonyl compounds using this ruthenium complex as a catalyst, and a method for producing N-alkylamine compounds using this ruthenium complex as a catalyst. The present invention pertains to a ruthenium complex represented by general formula (1) RuX 1 X 2 (PNP) (NHC) m (Solv) n (1) (in general formula (1), X 1 and X 2 each independently represent a monovalent anionic monodentate ligand; PNP represents a tridentate aminodiphosphine ligand, NHC represents an N-heterocyclic carbene derived from a nitrogen-containing heterocyclic ring, and Solv represents a coordinating solvent; and m represents an integer from 1 to 3, n represents an integer from 0 to 2, and 1≦m+n≦3.), a method for producing the same, a catalyst including the same, and methods for producing various organic compounds using this catalyst.

MODIFIED ORGANOMETALLIC FRAMEWORK AND CATALYST FOR HYDROGENATION REACTION INCLUDING SAME

The present disclosure relates to an organometallic framework modified using a compound having a hydroxyl group (—OH), a catalyst for a hydrogenation reaction including the same, and a method of manufacturing the same. The catalyst according to the present disclosure has high activity to the hydrogenation reaction even at a low temperature of 30 to 40° C., thus making low-grade waste heat usable.

HIGH ACTIVITY CATALYST FOR HYDROSILYLATION REACTIONS AND METHODS OF MAKING THE SAME

A heterogeneous catalyst comprising a metal-containing polymer matrix covalently bonded to a support material and a method of making and using such catalysts. The metal-containing polymer matrix comprises metal nano-particles encapsulated in a polymer matrix, e.g., a siloxane. In one aspect, the metal-containing polymer matrix can be bonded to the support material via a hydrophobic group attached to the support material. The catalyst can be recovered after being used in a metal catalyzed reaction and exhibit excellent catalytic activity upon reuse in subsequent reactions. 1. A heterogeneous catalyst comprising a metal-containing polymer matrix covalently bonded to a support material wherein the metal-containing polymer matrix comprises metal nanoparticles encapsulated in a polymer matrix chosen from an organic polymer matrix or a siloxane polymer matrix.2. (canceled)3. The catalyst of claim 1 , wherein the polymer matrix comprises an organic polymer matrix comprising a polymer or copolymer of a vinyl aromatic claim 1 , a vinyl halide claim 1 , an alpha monoolefin claim 1 , an acrylonitrile claim 1 , an acrylate claim 1 , an amide claim 1 , an acrylamide claim 1 , an ester claim 1 , or a combination of two or more thereof.4. The catalyst of claim 1 , wherein the polymer matrix is derived from a silicon hydride-containing polyorganohydrosiloxane of the general formula:{'br': None, 'sup': 1', '2', '1', '2', '1', '2, 'sub': a', 'b', 'c', 'd', 'e', 'f', 'j, 'MMDDTTQ'}{'sup': 1', '1', '2', '3', '2', '4', '5', '6', '1', '7', '8', '2', '9', '10', '1', '11', '2', '12', '1', '2', '3', '4', '5', '6', '7', '8', '9', '10', '11', '12', '4', '9', '12, 'sub': 1/2', '1/2', '2/2', '2/2', '3/2', '3/2', '4/2, 'wherein: M=RRRSiO; M=RRRSiO; D=RRSiO; D=RRSiO; T=RSiO; T=RSiO; Q=SiO; R, R, R, R, R, R, R, R, R, R, R, and Rare aliphatic, aromatic or fluoro monovalent hydrocarbon having from 1 to 60 carbon atoms; at least one of R, R, Ris hydrogen; and the subscript a, b, c, d, e, f, and j are ...

Rhodium catalyst and method for producing amine compound

[Problem] Provision of a superior rhodium catalyst and a production method of amine compound. [Solving Means] A rhodium complex coordinated with a compound represented by the formula

Redox Dehydration Coupling Catalysts and Methods Related Thereto

This disclosure relates to synthetic coupling methods using catalytic molecules. In certain embodiments, the catalytic molecules comprise heterocyclic thiolamide, S-acylthiosalicylamide, disulfide, selenium containing heterocycle, diselenide compound, ditelluride compound or tellurium containing heterocycle. Catalytic molecules disclosed herein are useful as catalysts in the transformation of hydroxy group containing compounds to amides, esters, ketones, and other carbon to heteroatom or carbon to carbon transformations

Catalytic Remedy for Advanced UCO Bleed Reduction in Recycle Hydrocracking Operations

A catalyst system has been designed that disrupts the sedimentation process. The catalyst system achieves this by saturating key feed components before the feed components are stripped into their incompatible aromatic cores. The efficacy of this disruptive catalyst system is particularly evident in a hydrocracker configuration that runs in two-stage-recycle operation. The catalyst is a self-supported multi-metallic catalyst prepared from a precursor in the hydroxide form, and the catalyst must be toward the top level of the second stage of the two-stage system.

RUTHENIUM ON CHITOSAN (ChRu): CONCERTED CATALYSIS FOR WATER SPLITTING AND REDUCTION

A process and catalyst for the in situ generation of hydrogen via the microwave irradiation of a ruthenium chitosan composite catalyst has enabled the convenient reduction of nitro compounds in aqueous medium.

RUTHENIUM-BASED COMPLEX CATALYSTS

The present invention provides novel Ruthenium-based transition metal complex catalysts comprising specific ligands, their preparation and their use in hydrogenation processes. Such complex catalysts are inexpensive, thermally robust, and olefin selective. 3. The catalyst according to claim 2 , wherein{'sup': 1', '2', '3', '1', '2', '3, 'L, L, Lrepresent identical or different ligands, wherein at least one of L, Land (if u=1) Lrepresents either a ligand having the general structure (Ia) or (Ib) or a ligand having the general structure (Ic) or (Id) and wherein'}{'claim-ref': {'@idref': 'CLM-00002', 'claim 2'}, 'n, R and E have the same meanings as given in , and'}D is identical or different and represents hydroxy, alkoxy, aryloxy, thiol, thiolate, thioether, sulfoxide, sulfone, phosphine oxide, phosphine sulfide, ketone, ester, or any moiety able of acting as a two electron donor.4. The catalyst according to in which{'sup': 1', '2, 'X, Xare identical or different and represent hydride, halide, in particular fluoride, chloride, bromide or iodide, pseudohalide, alkoxide, amide, tosylate, triflate, phosphate, borate, carboxylate, acetate, halogenated acetate, halogenated alkylsulfonate or a weekly coordinating anion,'}{'sup': 1', '2', '3, 'one ligand of L, L, and (if u=1) Lhas the general structure according to formulae (Ia) or (Ib), wherein'}n is identical or different and represents an integer in the range of from 1 to 20, preferably 1 to 10,{'sub': 1', '20', '6', '24', '1', '14', '1', '10, 'D is identical or different and represents hydroxy, alkoxy, aryloxy, thiol, thiolate, thioether, selenol, selenoether, amine, phosphine, phosphate, arsine, sulfoxide, sulfone, alkyl, phosphinimine, aminophosphine, carbene, selenoxide, imidazoline, imidazolidine, phosphine oxide, phosphine sulfide, phosphine selenide, ketone, ester, pyridyl, substituted pyridyl, or any other moiety able of acting as a two electron door, preferably D is identical or different and represents C-C- ...

HYDROGENATION OF BIOMASS-DERIVED SUBSTRATES

The α,β-unsaturated ketone moiety of a substrate representative of non-food based biomass was hydrogenated to the corresponding saturated alcohol moiety using a composition including (1) a copper salt; (2) a phosphine; (3) a polar aprotic solvent such as acetonitrile, and (4) a compound suitable for providing hydrogen for the hydrogenation, such as a suitable silane material or a suitable siloxane material. 1. A composition effective for hydrogenation of an α ,β-unsaturated ketone moiety of a substrate comprising a furan ring , said catalyst prepared by combining a copper salt , a phosphine , a dry polar aprotic solvent , and a silane material or siloxane material , said silane material or siloxane material suitable for providing hydrogen for hydrogenation of the α ,β-unsaturated ketone moiety of a substrate.2. The composition of wherein the phosphine is selected from bis(diethylphosphino)ethane and 1 claim 1 ,3-bis(diisopropylphosphino)propane.3. The composition of claim 2 , wherein the copper salt comprises copper(II) fluoride.4. The composition of claim 2 , wherein the copper salt is copper(I) chloride and the composition further comprises a material that reacts with copper(I) chloride to provide a composition effective for hydrogenation of the α claim 2 ,β-unsaturated ketone moiety of the substrate comprising a furan ring.5. The composition of claim 1 , wherein the suitable silane material comprises phenyl silane.6. The composition of claim 1 , wherein the suitable siloxane material comprises polymethylhydrosiloxane.7. The composition of claim 1 , wherein the solvent comprises acetonitrile.8. A process for hydrogenation of an α claim 1 ,β-substituted moiety of a furan-containing substrate claim 1 , comprising reacting the substrate with a composition prepared by combining a copper salt claim 1 , a phosphine claim 1 , a polar aprotic solvent claim 1 , and a material suitable for providing hydrogen for the hydrogenation claim 1 , said suitable material selected ...

NOVEL RUTHENIUM COMPLEX AND METHOD FOR PREPARING METHANOL AND DIOL

Provided is a method for preparing methanol and diol from cyclic carbonate, comprising: under a hydrogen atmosphere, in an organic solvent, and with the presence of a ruthenium complex (Ru(L)XYY′) and an alkali, conducting a hydrogenation reduction reaction on the cyclic carbonate or polycarbonate to obtain methanol and diol. Also provided is a ruthenium complex prepared from ruthenium and a tridentate amido diphosphine ligand. Also provided is a deuterated methanol and deuterated diol preparation method by substituting the hydrogen and ruthenium complex with deuterium. 2. The method according to claim 1 , wherein the catalyst is a compound of transition metal of Group VIIIB.3. The method according to claim 2 , wherein the transition metal of Group VIIIB is selected from Fe claim 2 , Co claim 2 , Ni claim 2 , Ru claim 2 , Rh claim 2 , Pd claim 2 , Os claim 2 , Ir or Pt.6. The method according to claim 4 , wherein the molar ratio of the cyclic carbonate or polycarbonate to ruthenium complex is 100˜1000000:1.7. The method according to claim 4 , wherein the base is an alkali metal salt of alcohol claim 4 , an alkali metal carbonate claim 4 , or an alkali metal hydroxide.8. The method according to claim 4 , wherein the molar ratio of base to ruthenium complex is 1 to 100:1.9. The method according to claim 4 , wherein the temperature for the reaction is 60-180° C.10. The method according to claim 4 , wherein the reaction time for the reaction is 0.1-1000 hours.11. The method according to claim 4 , wherein the hydrogen pressure for the reaction is 1-100 atmospheres.1411. A method for preparing deuterated methanol and deuterated diol claims 1 , wherein the method includes performing the method according to any one of - by using deuterium Dinstead of hydrogen H claims 1 , so as to give deuterated methanol and deuterated diol. The present invention relates to the field of organic synthesis. In particular, the present invention relates to a method for preparing methanol and ...

METHOD FOR PRODUCING NOVEL ORGANOMETALLIC COMPLEX AND AMINE COMPOUND

The purpose of the invention is to provide a novel organometallic compound that can be utilized as a catalyst having high generality, high activity, and excellent functional group selectivity. The invention pertains to a novel organometallic compound represented by general formula (1) that catalyzes a reductive amination reaction. 2. The organometallic compound according to claim 1 , wherein the electron-withdrawing group is —S(═O)—R claim 1 , a 6- to 20-membered aryl group in which a carbon atom may be replaced by a heteroatom claim 1 , —C(═O)—OR claim 1 , —C(═O)—R claim 1 , —C(═O)—NRR claim 1 , —C(═S)—NRR claim 1 , a C1-C20 sulfenyl group or a perfluoroalkyl group claim 1 , in which one or more hydrogen atoms of these groups may be substituted by a substituent W.3. The organometallic compound according to claim 1 , wherein the electron-withdrawing group is —S(═O)—R claim 1 , —C(═O)—R claim 1 , or —C(═O)—NRR claim 1 , in which one or more hydrogen atoms of these groups may be substituted by a substituent W.4. The organometallic compound according to claim 1 , characterized in that Ar is a cyclopentadienyl group in which one or more hydrogen atoms may be substituted by a substituent W claim 1 , and M is iridium or rhodium.5. The organometallic compound according to claim 1 , characterized in that n=0.6. The organometallic compound according to claim 1 , wherein A is a saturated or unsaturated 4- to 6-membered heterocycle having only one nitrogen atom as the ring member heteroatom.7. The organometallic compound according to claim 1 , wherein A is a saturated or unsaturated 4- to 6-membered heterocycle comprising one or more heteroatoms selected from the group consisting of nitrogen atom claim 1 , oxygen atom and sulfur atom claim 1 , in addition to one nitrogen atom.8. The organometallic compound according to claim 1 , wherein A is an aromatic ring.9. The organometallic compound according to claim 1 , wherein an organometallic complex of general formula (1) is an ...

MONONUCLEAR RUTHENIUM COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME

A neutral or cationic mononuclear ruthenium divalent complex represented by formula (1) can actualize exceptional catalytic activity in at least one reaction among a hydrosilylation reaction, hydrogenation reaction, and carbonyl compound reduction reaction. 2. The neutral or cationic mononuclear divalent ruthenium complex of claim 1 , wherein L is at least one type of two-electron ligand selected from the group consisting of molecular hydrogen claim 1 , amines claim 1 , imines claim 1 , nitrogen-containing heterocycles claim 1 , phosphines claim 1 , phosphites claim 1 , arsines claim 1 , alcohols claim 1 , thiols claim 1 , ethers claim 1 , sulfides claim 1 , nitriles claim 1 , isonitriles claim 1 , aldehydes claim 1 , ketones claim 1 , alkenes of 2 to carbon atoms claim 1 , alkynes of 2 to 30 carbon atoms and triorganohydrosilanes.4. The neutral or cationic mononuclear divalent ruthenium complex of claim 3 , wherein Lis at least one type of two-electron ligand selected from the group consisting of isonitriles claim 3 , nitrogen-containing heterocycles and phosphites (with the proviso that when a plurality of Lligands are present claim 3 , two Lligands may be bonded to one another).5. The neutral or cationic mononuclear divalent ruthenium complex of or claim 3 , wherein Lis a triorganohydrosilane (with the proviso that when a plurality of Lligands are present claim 3 , two Lligands may be bonded to one another).6. The neutral or cationic mononuclear divalent ruthenium complex of claim 3 , wherein mand mare both 2.7. The neutral or cationic mononuclear divalent ruthenium complex of claim 6 , wherein Rto Rare each independently an alkyl claim 6 , aryl or aralkyl group that may be substituted with X claim 6 , which is as defined above claim 6 , and{'sup': 2', '7', '8', '9', '10', '11', '12', '7', '12, 'the Lligands are triorganohydrosilanes of the formulas H—SiRRRand H—SiRRR(wherein Rto Rare each independently an alkyl, aryl or aralkyl group that may be substituted with ...

Transition metal isonitrile catalysts

The present disclosure relates to new transition metal isonitrile compounds, processes for the production of the compounds and the use of the compounds as catalysts. The disclosure also relates to the use of the metal isonitrile compounds as catalysts for hydrogenation and transfer hydrogenation of compounds containing one or more carbon-oxygen, and/or carbon-nitrogen and/or carbon-carbon double bonds.

RUTHENIUM-DIAMINE COMPLEXES AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS

Provided is a catalyst for asymmetric reduction, which can be produced by a convenient and safe production method, has a strong catalytic activity, and has excellent stereoselectivity. The present invention relates to a ruthenium complex represented by the following formula (1): wherein Rrepresents an alkyl group or the like; Y represents a hydrogen atom; X represents a halogen atom or the like; j and k each represent 0 or 1; Rand Reach represent an alkyl group or the like; Rto Reach represent a hydrogen atom, an alkyl group or the like; Z represents oxygen or sulfur; nrepresents 1 or 2; and nrepresents an integer from 1 to 3, a method for producing the ruthenium complex, a catalyst for asymmetric reduction formed from the ruthenium complex, and methods for selectively producing an optically active alcohol and an optically active amine using the catalyst for asymmetric reduction. 12-. (canceled)4. A method for producing a reduction product by reducing an organic compound in the presence of the ruthenium complex as set forth in and a hydrogen donor.5. A method for producing an optically active alcohol claim 3 , the method comprising reducing a carbonyl group of a carbonyl compound in the presence of the ruthenium complex according to and a hydrogen donor.6. A method for producing an optically active amine claim 3 , the method comprising reducing an imino group of an imine compound in the presence of the ruthenium complex according to and a hydrogen donor.7. The method according to claim 4 , wherein the hydrogen donor is selected from formic acid claim 4 , a formic acid alkali metal salt claim 4 , and an alcohol having a hydrogen atom on the α-position carbon atom substituted with a hydroxyl group.8. The method according to claim 4 , wherein the hydrogen donor is hydrogen.9. A catalyst for reduction claim 3 , comprising the ruthenium complex according to .10. The catalyst according to claim 9 , wherein the catalyst is a catalyst for asymmetric reduction. The present ...

RUTHENIUM-PHENOL CATALYSTS AND METHOD OF PREPARING MENTHONE FROM ISOPULEGOL

The present invention is directed towards a catalyst which is obtainable by contacting in situ a ruthenium precursor and a phenol derivative. Furthermore, the present invention is directed towards the use of said catalyst in transfer hydrogenation reactions. In particular, the present invention is directed to a method for preparing menthone starting from isopulegol. 115.-. (canceled)17. The method of wherein{'sup': 1', '2', '3', '4, 'R, R, R, Rindependently are hydrogen, branched or linear alkyl, or hydroxy, or'}{'sup': 3', '4, 'R, Rtogether with the carbon atoms to which they are bound form an anellated aromatic ring (e.g. phenyl);'}{'sup': '5a', 'Ris hydrogen, alkyl branched or linear alkyl, or hydroxy;'}{'sup': 6', '7', '8', '9, 'R, R, R, Rindependently are hydrogen, or branched or linear alkyl, or'}{'sup': 6', '7, 'R, Rtogether with the carbon atoms to which they are bound form an anellated aromatic ring;'}{'sup': '10', 'Ris hydrogen or hydroxy, and'}X is a chemical bond, alkylene optionally substituted by 1, 2 or 3 substituents which are independently selected from the group consisting of halogen, alkyl, substituted alkyl, cycloalkyl, aryl, and OH, or —O—.20. The method of wherein{'sup': 1', '2', '3', '4, 'sub': 1', '10', '3', '10, 'R, R, R, Rindependently are hydrogen, linear C-C-alkyl, or branched C-C-alkyl, or'}{'sup': 3', '4, 'R, Rtogether with the carbon atoms to which they are bound form an anellated aromatic ring;'}{'sup': 6', '7', '8', '9, 'sub': 1', '10', '3', '10, 'R, R, R, Rindependently are hydrogen, linear C-C-alkyl, or branched C-C-alkyl, or'}{'sup': 6', '7, 'R, Rtogether with the carbon atoms to which they are bound form an anellated aromatic ring;'}{'sup': '10', 'Ris hydrogen or hydroxy, and'}X is a chemical bond or alkylene.21. The method of wherein the ruthenium precursor having labile ligands is of formula (II) or a salt thereof{'br': None, 'sub': m', 'n, '[RuL]\u2003\u2003(II)'}whereinRu is in the oxidation state (+II), (+III) or (+IV);each ...

ENANTIOPURE TERPHENYLS WITH TWO ORTHO-ATROPISOMERIC AXES

Enantiopure terphenyl presenting two ortho-located chiral axes having the following structural formula (I): their process of synthesis and their use as mono or bidentate ligands for asymmetric organometallic reactions, as organocatalysts, as chiral base and as generator, with metal, of isolable chiral metallic complexes for applications in asymmetric catalysis and others. 2. The enantiopure terphenyl according to claim 1 , wherein{'sub': '1', 'claim-text': an halogen atom,', 'a substituted or unsubstituted branched or straight alkyl group or', 'a substituted or unsubstituted branched or straight alkoxy group or', {'sub': '3', 'a CFgroup,'}], 'Rrepresents'}{'sub': '2', 'claim-text': a hydrogen atom or', 'a substituted or unsubstituted branched or straight alkyl group, or', 'a substituted or unsubstituted branched or straight alkoxy group, 'Rrepresents'}{'sub': '3', 'claim-text': a substituted or unsubstituted branched or straight alkyl group or', 'a substituted or unsubstituted branched or straight alkoxy group,, 'Rrepresents'}{'sub': '4', 'claim-text': a hydrogen atom or', 'a halogen atom or', 'a substituted or unsubstituted branched or straight alkoxy group, or', 'a substituted or unsubstituted branched or straight alkyl group or', 'a aryl group or', {'sub': 2', '2', 'n+2, 'a CHF group, or a CHFgroup or —CnFgroup avec n=1 à 10, or'}], 'Rrepresents'}{'sub': '5', 'claim-text': [{'sub': a', 'a', '1', '4, 'a SORgroup with Rselected from a substituted or unsubstituted branched or straight-(C-C) alkyl group or a substituted or unsubstituted aryl group, or'}, 'a OH group, or', {'sub': a', 'd', 'a', 'd', 'a', 'd, '—PRnor a —P(O)Rnwith Rand Rindependently selected from a substituted or unsubstituted branched or straight alkyl group or a substituted or unsubstituted aryl group,'}], 'Rrepresents'}{'sub': '6', 'claim-text': a hydrogen atom,', 'a halogen atom or', {'sub': 1', '4, 'a substituted or unsubstituted branched or straight-(C-C) alkyl group or'}, {'sub': 1', '4, 'a ...

Catalyst compounds

The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formula: (Formula (I)) where ring B is a conjugated ring system with one or more substituents. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.

Semi-permeable particles having metallic catalysts and uses

Semi-permeable particle can be used to facilitate chemical reactions. The semi-permeable particles are permeable to molecules having a molar mass of 1000 Daltons or less, have a mode particle size of at least 1 μm, and comprise nanoparticles of catalytically active metallic materials disposed within at least some of multiple discrete cavities in the continuous polymeric phase. The nanoparticles of catalytically active metallic materials (a) comprise one or more elements selected from Groups 8, 9, 10, and 11 of the Periodic Table, and (b) have an effective diameter of at least 1 nm and up to and including 200 nm.

Metal Supported Powder Catalyst Matrix and Processes for Multiphase Chemical Reactions

A catalytic membrane composite that includes porous supported catalyst particles durably enmeshed in a porous fibrillated polymer membrane is provided. The porous fibrillated polymer membrane may be manipulated to take the form of a tube, disc, or diced tape and used in multiphase reaction systems. The supported catalyst particles are composed of at least one finely divided metal catalyst dispersed on a porous support substrate. High catalytic activity is gained by the effective fine dispersion of the finely divided metal catalyst such that the metal catalyst covers the support substrate and/or is interspersed in the pores of the support substrate. In some embodiments, the catalytic membrane composite may be introduced to a stirred tank autoclave reactor system, a continuous flow reactor system, or a Parr Shaker reaction system and used to effect the catalytic reaction. 1. A continuous flow reaction system for multiphase reactions having at least three phases , said reaction system comprising:a catalytic article comprising a porous fibrillated polymer membrane that includes supported catalyst particles durably enmeshed within the porous fibrillated polymer membrane, said catalytic article being in the form of diced tape;a liquid phase comprising at least one liquid phase reactant;a gas phase comprising at least one gas phase reactant; anda reaction vessel in the form of a continuous loop and being configured for continuous flow of the liquid phase reactant and the gas phase reactant across and through the catalytic article.2. The reaction system of claim 1 , wherein the catalytic article is not configured as a contactor.3. The reaction system of claim 1 , wherein the reaction system is configured for hydrogenation.4. The reaction system of claim 1 , wherein the porous fibrillated polymer membrane is insoluble to reactants and products in the multiphase chemical reaction.5. The reaction system of claim 1 , wherein the porous fibrillated polymer membrane comprises ...

CATALYSTS BASED ON AMINO-SULFIDE LIGANDS FOR HYDROGENATION AND DEHYDROGENATION PROCESSES

The present application discloses novel amino-sulfide metal catalysts for organic chemical syntheses including hydrogenation (reduction) of unsaturated compounds or dehydrogenation of substrates. The range of hydrogenation substrate compounds includes esters, lactones, oils and fats, resulting in alcohols, diols, and triols as reaction products. The catalysts of current application can be used to catalyze a hydrogenation reaction under solvent free conditions. The present catalysts also allow the hydrogenation to proceed without added base, and it can be used in place of the conventional reduction methods employing hydrides of the main-group elements. Furthermore, the catalysts of the present application can catalyze a dehydrogenation reaction under homogenous and/or acceptorless conditions. As such, the catalysts provided herein can be useful in substantially reducing cost and improving the environmental profile of manufacturing processes for a variety of chemicals. 2. (canceled)3. (canceled)4. A process for dehydrogenation of a substrate comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'treating the substrate with a catalytic amount of a metal complex of .'}6. (canceled)7. The process of claim 5 , wherein the substrate comprises more than one hydroxyl moiety that undergoes dehydrogenation.8. (canceled)10. A process for producing Hcomprising dehydrogenation of a substrate by treating the substrate with a catalytic amount of a metal complex of .11. The process of claim 10 , wherein the substrate comprises an alcohol claim 10 , amine or thiol or wherein the substrate is ammonia-borane.12. (canceled)13. The process of claim 4 , wherein the process does not require a hydrogen acceptor.14. The process of claim 4 , which is a homogeneous process.15. A process for hydrogenation of a substrate comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'treating the substrate under a pressure of hydrogen with a catalytic amount of a metal complex of .'}16. The ...

CATALYST COMPOUNDS

The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions. 2. (canceled)3. The catalyst compound of claim 1 , wherein ring A of the Formula I or ring A of the Formula A is phenyl claim 1 , optionally substituted claim 1 , in either or both of the ortho- or para-position relative to the imine nitrogen atom to which ring A is attached claim 1 , by one or two groups each independently selected from the group consisting of hydroxyl claim 1 , NRR claim 1 , (1-3C)alkyl claim 1 , (1-3C)alkoxy and aryl which is optionally substituted by halogeno claim 1 , hydroxyl claim 1 , NRR claim 1 , (1-3C)alkyl or (1-3C)alkoxy claim 1 , wherein Rand Rare each independently hydrogen or (1-2C)alkyl.4. The catalyst compound of claim 1 , wherein ring A of the Formula I or ring A of the Formula A is para-methoxyphenyl.5. The catalyst compound of claim 1 , wherein ring B of the Formula I is naphthyl claim 1 , optionally substituted by one or more groups selected from the group consisting of halogeno claim 1 , hydroxyl claim 1 , NRR claim 1 , (1-6C)alkyl claim 1 , (1-6C)alkoxy claim 1 , [NRRR] claim 1 , nitro claim 1 , cyano claim 1 , formyl claim 1 , carboxy claim 1 , carbamoyl claim 1 , sulphamoyl claim 1 , ureido claim 1 , isocyano claim 1 , sulphonyl claim 1 , sulphonate claim 1 , trihalomethyl claim 1 , and mercapto claim 1 , wherein R claim 1 , R claim 1 , and Rare each independently hydrogen claim 1 , (1-6C)alkyl or aryl claim 1 , or a group of the formula:{'br': None, 'sub': 1', '1, 'L-Q'}wherein:{'sub': 1', '2', '2', '2, 'sup': f', 'f', 'f', 'f', 'f', 'g', 'f', 'f', 'f', 'g, 'Lis ...

USE OF ORGANIC DOPANTS TO ENHANCE ACETYLENE HYDROGENATION CATALYSTS

A composition comprising a supported hydrogenation catalyst comprising palladium and a support, wherein the supported hydrogenation catalyst is capable of selectively hydrogenating highly unsaturated hydrocarbons to unsaturated hydrocarbons; and a dopant comprising a fluorene structure. A method of making a selective hydrogenation catalyst including contacting a support with a palladium-containing compound to form a supported-palladium composition; contacting the supported-palladium composition with a dopant comprising a fluorene structure group to form a selective hydrogenation catalyst precursor; and reducing the selective hydrogenation catalyst precursor to form the selective hydrogenation catalyst. A method of selectively hydrogenating highly unsaturated hydrocarbons to an unsaturated hydrocarbon enriched composition by contacting a supported catalyst comprising palladium and a dopant comprising a fluorene structure with a feed comprising highly unsaturated hydrocarbon under conditions suitable for hydrogenating at least a portion of the highly unsaturated hydrocarbon feed to form the unsaturated hydrocarbon enriched composition. 2. The composition of claim 1 , wherein the dopant further comprises at least one substituent selected from the group consisting of carboxyl groups claim 1 , hydroxyl groups claim 1 , carbonyl groups claim 1 , amide groups claim 1 , phenyl groups claim 1 , substituted phenyl groups claim 1 , and combinations thereof.3. The composition of claim 2 , wherein the at least one substituent is located on the 1 claim 2 , 2 claim 2 , 4 claim 2 , or 9 position of the fluorene structure.4. The composition of claim 3 , wherein the dopant comprises 9-phenyl-9-fluorenol claim 3 , 9-hydroxyfluorene claim 3 , 2-hydroxyfluorene claim 3 , 9-(2-(hydroxymethyl)phenyl)-9-fluorenol claim 3 , fluorene-9-carboxylic acid claim 3 , fluorene-1-carboxylic acid claim 3 , fluorene-4-carboxylic acid claim 3 , fluorenone claim 3 , fluorene claim 3 , or a combination ...

USE OF CHARGE-CONTAINING MOLECULES LINKED WITH COVALENT BONDS TO ENHANCE ACETYLENE HYDROGENATION CATALYSTS

A composition containing a supported hydrogenation catalyst comprising palladium and a support, wherein the supported hydrogenation catalyst is capable of selectively hydrogenating highly unsaturated hydrocarbons to unsaturated hydrocarbons, and a dopant, wherein the dopant comprises at least one component selected from zwitterions, ylides, betaines, or combinations thereof. A method of making a selective hydrogenation catalyst by contacting a support with a palladium-containing compound to form a supported-palladium composition, contacting the supported-palladium composition with a dopant to form a selective hydrogenation catalyst precursor, wherein the dopant comprises at least one component selected from zwitterions, ylides, betaines, or combinations thereof, and reducing the selective hydrogenation catalyst precursor to form the selective hydrogenation catalyst. A selective hydrogenation catalyst produced via the method of making a selective hydrogenation catalyst, and a method of selectively hydrogenating highly unsaturated hydrocarbons to an unsaturated hydrocarbon enriched composition are also provided. 1. A composition comprising:a supported hydrogenation catalyst comprising palladium and an inorganic support selected from the group consisting of aluminas, silicas, titanias, zirconias, aluminosilicates, spinets, and combinations thereof, wherein the supported hydrogenation catalyst is capable of selectively hydrogenating highly unsaturated hydrocarbons to unsaturated hydrocarbons; anda dopant, wherein the dopant comprises at least one component selected from the group consisting of zwitterions, ylides, betaines, and combinations thereof.2. The composition of claim 1 , wherein the dopant is selected from ylides.3. The composition of claim 2 , wherein the dopant is selected from phosphorus ylides.4. The composition of claim 3 , wherein the dopant is selected from phosphorus ylides further comprising a carbonyl group.5. The composition of claim 2 , wherein the ...

PROCESS FOR PRODUCING HETEROCYCLIC COMPOUND

The present invention provides a method of efficiently producing an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative. The optically active piperidine-3-carboxamide or a derivative thereof, which is obtained by subjecting 1,4,5,6-tetrahydropyridine-3-carboxamide or a derivative thereof to an asymmetric reduction in the presence of a catalyst, is used as an intermediate. 2. The method according to claim 1 , wherein the organic metal complex is a transition metal complex.3. The method according to claim 2 , wherein the transition metal complex is a ruthenium complex.4. The method according to claim 3 , wherein the ruthenium complex is represented by the formula:{'br': None, 'sup': 'a', 'sub': '2', '[Ru(OCOR)L*]\u2003\u2003(VIII)'}wherein{'sup': 'a', 'sub': '1-3', 'Ris an optionally substituted Calkyl group; and'}{'sup': 'a', 'Lis a diphosphine ligand.'} This application is a divisional of U.S. application Ser. No. 15/125,299, which is the U.S. National Stage application of PCT/JP2015/057541, filed Mar. 13, 2015, which claims priority from Japanese application 2014-052809, filed Mar. 14, 2014.The present invention relates to a production method of an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative which is useful as a dipeptidylpeptidase inhibitor, and various intermediates useful therefor, and production methods thereof.An optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative is known to be useful as a dipeptidylpeptidase inhibitor and an agent for the treatment of diabetes.Patent Document 1 discloses a method of producing a 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative by reacting optically active 3-aminopiperidine with a 6-chloro-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative.Patent Document 2 discloses a method of efficiently producing an optically active 8-(3-aminopiperidin-1-yl)xanthine derivative by ...

Catalysts and processes for the hydrogenation of amides

There is provided a process for the reduction of one or more amide moieties in a compound comprising contacting the compound with hydrogen gas and a transition metal catalyst in the presence or absence of a base under conditions for the reduction an amide bond. The presently described processes can be performed at low catalyst loading using relatively mild temperature and pressures, and optionally, in the presence or absence of a base or high catalyst loadings using low temperatures and pressures and high loadings of base to effect dynamic kinetic resolution of achiral amides.

Catalytic conversion of carbon dioxide to methanol

The present disclosure relates to a new catalytic process for the production of methanol from carbon dioxide, comprising: (1) the conversion of carbon dioxide and hydrogen to formic acid or formate salts; (2) converting the formic acid or formate salts to diformate esters of diols; (3) hydrogenating the diformate esters to methanol and diols. The diols produced from the hydrogenation reaction can be recovered and re-used to prepare the diformate esters.

Spiroketal-Based C2-Symmetric Scaffold For Asymmetric Catalysis

Provided herein is a compound of formula (I): 4. The compound of claim 1 , wherein at least one X is OH.5. (canceled)6. The compound of claim 1 , wherein at least one X is PAr.7. (canceled)8. The compound of claim 1 , wherein at least one X is OPAr.9. (canceled)10. The compound of claim 1 , wherein at least one X is P(O)Ar.1112.-. (canceled)13. The compound of claim 6 , wherein Ar comprises phenyl.14. The compound of claim 1 , wherein both X together form OPNR′.1518.-. (canceled)19. The compound of claim 14 , wherein R′ is methyl.2022.-. (canceled)23. The compound of claim 1 , wherein R is ethyl.2428.-. (canceled)29. The compound of claim 1 , wherein at least one R is 3-10 membered heterocycloalkyl having 1-4 heteroatoms independently selected from N claim 1 , O claim 1 , and S.3034.-. (canceled)36. A catalyst comprising the compound of formula (I) according to and a transition metal.37. The catalyst of claim 36 , wherein the transition metal comprises iridium claim 36 , palladium claim 36 , rhodium claim 36 , platinum claim 36 , copper claim 36 , nickel claim 36 , cobalt claim 36 , or gold.38. A method of preparing the catalyst of comprising admixing the compound of formula (I) and the transition metal to form the catalyst.39. (canceled)40. The method of claim 38 , wherein the transition metal comprises [Ir(COD)Cl] claim 38 , [Pd(allyl)Cl] claim 38 , or Pd(dba).41. The method of claim 38 , wherein the compound of formula (I) and the transition metal are provided in a molar ratio of about 6:1 to 1:1.42. A method comprising:{'claim-ref': {'@idref': 'CLM-00036', 'claim 36'}, 'admixing a first reactant, a second reactant, and the catalyst of under conditions sufficient to allow reaction of the first reactant and the second reactant to form a reaction product, wherein the reaction product comprises a chiral center and the reaction produces an enantiomeric excess (ee) of the reaction product.'}43. The method of claim 42 , wherein the reaction comprises a hydroarylation ...

NOVEL DIAMINE COMPOUND AND METAL COMPLEXES, AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS

The present invention relates to a novel diamine compound represented by the general formula (1), a ruthenium-diamine complex, an iridium-diamine complex, and a rhodium-diamine complex having the diamine compound as a ligand. Furthermore, the present invention relates to methods for selectively producing optically active compounds by using any of these complexes as a catalyst. 3. A method for producing an optically active amine or an optically active compound , comprising:{'claim-ref': {'@idref': 'CLM-00002', 'claim 2'}, 'reducing an imino group of an imine compound or an unsaturated bond of a heterocyclic compound in the presence of the complex according to and a hydrogen donor.'}4. The production method according to claim 3 , wherein the hydrogen donor is hydrogen.5. The production method according to claim 3 , wherein the hydrogen donor is selected from formic acid claim 3 , alkali metal formates claim 3 , and alcohols having a hydrogen atom on a carbon atom at an α-position of a carbon atom substituted with a hydroxyl group.6. A catalyst for asymmetric reduction claim 2 , comprising the complex according to .7. A method for asymmetric reduction of an imine compound or a heterocyclic compound comprising: reducing an imino group of the imine compound or an unsaturated bond of the heterocyclic compound in the presence of a catalyst comprising the complex according to and a hydrogen doner. The present invention relates to a novel diamine compound, a ruthenium-diamine complex, an iridium-diamine complex, and a rhodium-diamine complex having the diamine compound as a ligand, and methods for selectively producing optically active compounds important as precursors for synthesis of pharmaceuticals and functional materials by using any of these complexes as a catalyst.In the field of production of optically active amines, many asymmetric reactions including asymmetric reduction have been developed, and many asymmetric reactions using asymmetric metal complexes having ...

Low system memory detection

Methods, systems, and computer readable media may be operable to facilitate an anticipation of an execution of a process termination tool. An allocation stall counter may be queried at a certain frequency, and from the query of the allocation stall counter, a number of allocation stall counter increments occurring over a certain duration of time may be determined. If the number of allocation stall counter increments is greater than a threshold, a determination may be made that system memory is running low and that an execution of a process termination tool is imminent. In response to the determination that system memory is running low, a flag indicating that system memory is running low may be set, and one or more programs, in response to reading the flag, may free memory that is not necessary or required for execution.

Liquid hydrogen storage material and method of storing hydrogen using the same

Provided is a liquid hydrogen storage material including 1,1′-biphenyl and 1,1′-methylenedibenzene, the liquid hydrogen storage material including the corresponding 1,1′-biphenyl and 1,1′-methylenedibenzene at a weight ratio of 1:1 to 1:2.5. The corresponding liquid hydrogen storage material has excellent hydrogen storage capacity value by including materials having high hydrogen storage capacity, and is supplied in a liquid state, and as a result, it is possible to minimize initial investment costs and the like required when the corresponding liquid hydrogen storage material is used as a hydrogen storage material in a variety of industries.

Method for preparing aromatic amino acid derivative

The present invention provides methods of efficiently producing various optically active aromatic amino acid derivatives by reacting, using an additive, a specific ester compound with an aromatic halide and zinc in the presence of a catalyst. The present invention also provides amino acid derivatives that can be produced by the methods.

Supported Metal Catalysts

The present invention relates to supported metal catalysts, wherein the catalysts are modified by at least one amine, a method for the preparation thereof and hydrogenation processes utilising the supported metal catalysts. 2. The supported metal catalyst of claim 1 , wherein the support is carbon claim 1 , alumina claim 1 , calcium carbonate claim 1 , titania claim 1 , silica claim 1 , zirconia claim 1 , ceria claim 1 , or a combination thereof.3. The supported metal catalyst of claim 2 , wherein the alumina is alpha-AlO claim 2 , beta-AlO claim 2 , gamma-AlO claim 2 , delta-AlO claim 2 , theta-AlOor a combination thereof.4. The supported metal catalyst of claim 2 , wherein the carbon is activated carbon claim 2 , carbon black claim 2 , graphite claim 2 , or a combination thereof.5. (canceled)6. (canceled)7. The supported metal catalyst of claim 1 , wherein the metal is ruthenium claim 1 , rhodium claim 1 , palladium claim 1 , osmium claim 1 , iridium claim 1 , platinum claim 1 , gold claim 1 , silver claim 1 , copper claim 1 , iron claim 1 , cobalt claim 1 , nickel claim 1 , or a combination thereof.8. The supported metal catalyst of claim 1 , wherein the metal is palladium claim 1 , platinum claim 1 , gold claim 1 , or a combination thereof.9. The supported metal catalyst of claim 1 , wherein the Group VIII or IB metal is present in a range of from 0.01 wt % to 20 wt % claim 1 , relative to the total weight of the supported metal catalyst.10. The supported metal catalyst of claim 1 , wherein the amine is a natural amino acid claim 1 , non-natural amino acid claim 1 , peptide claim 1 , alkylamine claim 1 , alkyldiamine claim 1 , alkylpolyamine claim 1 , or combinations thereof.11. The supported metal catalyst of claim 10 , wherein the amine is lysine claim 10 , glycine claim 10 , proline claim 10 , alanine claim 10 , serine claim 10 , phenylalanine claim 10 , asparagine claim 10 , aspartic acid claim 10 , valine claim 10 , butylamine claim 10 , 6-aminocaproic acid ...

NANO-TO-NANO FE/PPM Pd CATALYSIS OF CROSS-COUPLING REACTIONS IN WATER

In one embodiment, the present application discloses a catalyst composition comprising: a) a reaction solvent or a reaction medium; b) organometallic nanoparticles comprising: i) a nanoparticle (NP) catalyst, prepared by a reduction of an iron salt in an organic solvent, wherein the catalyst comprises at least one other metal selected from the group consisting of Pd, Pt, Au, Ni, Co, Cu, Mn, Rh, Ir, Ru and Os or mixtures thereof; c) a ligand; and d) a surfactant; wherein the metal or mixtures thereof is present in less than or equal to 50,000 ppm relative to the iron salt. 120.-. (canceled)22. The method of claim 21 , wherein the metal claim 21 , other than Pd claim 21 , is selected from the group consisting of Pt claim 21 , Au claim 21 , Ni claim 21 , Co claim 21 , Cu claim 21 , Mn claim 21 , Rh claim 21 , Ir claim 21 , Ru and Os or a mixture thereof.23. The method of further comprising:iii) contacting the product mixture with an organic solvent to form an organic phase and an aqueous phase; andiv) separating the organic phase from the aqueous phase containing the micelle composition as well as the iron/ppm Pd nanoparticles.24. The method of further comprising:v) re-cycling the aqueous phase containing the micelle composition and Fe/ppm Pd nanoparticles for use in a subsequent cross coupling or other reactions.25. The method of claim 21 , wherein the reaction solvent is water claim 21 , and the reaction solvent further comprising an organic solvent claim 21 , wherein the organic co-solvent is present in at least 5% claim 21 , 10% claim 21 , 20% claim 21 , 30% claim 21 , 40% claim 21 , 50% claim 21 , 70% claim 21 , 80% or at least 90% wt/wt.2611. The method of claim claim 21 , wherein the organic co-solvent is present at a wt of organic co-solvent to the wt of water (wt/wt) of 1/10 claim 21 , 2/10 claim 21 , 5/10 claim 21 , 10/10 claim 21 , 20/10 claim 21 , 30/10 claim 21 , 50/10 claim 21 , 70/10 claim 21 , 90/10 claim 21 , 100/10 claim 21 , 200/10 claim 21 , 300/10 ...

Monocarbonyl ruthenium and osmium catalysts

The invention relates to monocarbonyl complexes of ruthenium and osmium with bi- and tridentate nitrogen and phosphine ligands. The invention relates to methods for preparing these complexes and the use of these complexes, isolated or prepared in situ, as catalysts for reduction reactions of ketones and aldehydes both via transfer hydrogenation or hydrogenation with hydrogen.

LIGAND, METAL COMPLEX CONTAINING LIGAND, AND REACTION USING METAL COMPLEX CONTAINING LIGAND

A hydrogen transfer reaction may be more efficiently promoted by using a metal complex represented by Formula (2): 37-. (canceled)911-. (canceled)13. A method for producing a hydrogen transfer reaction product , comprising the step of:{'claim-ref': {'@idref': 'CLM-00008', 'claim 8'}, 'subjecting an organic compound to a dehydrogenation reaction (oxidation reaction) in the presence of the compound according to .'}14. (canceled)16. A method for producing a hydrogen transfer reaction product , comprising the step of:{'claim-ref': {'@idref': 'CLM-00015', 'claim 15'}, 'subjecting an organic compound to a hydrogenation reaction in the presence of the catalyst for hydrogenation reaction according to .'}19. The compound according to claim 18 , wherein claim 18 , in Formula (2a) claim 18 , Rare the same or different claim 18 , and each represents a methyl group claim 18 , ethyl group claim 18 , n-propyl group claim 18 , isopropyl group claim 18 , n-butyl group claim 18 , isobutyl group claim 18 , sec-butyl group claim 18 , pentyl group claim 18 , hexyl group claim 18 , or Ccycloalkyl group.21. A method for producing a dehydrogenation reaction product claim 18 , comprising the step of:{'claim-ref': {'@idref': 'CLM-00020', 'claim 20'}, 'subjecting an organic compound to a dehydrogenation reaction in the presence of the catalyst for dehydrogenation reaction according to .'}23. The compound according to claim 22 , wherein claim 22 , in Formula (2a) claim 22 , Rare the same or different claim 22 , and each represents a linear or branched Calkyl group claim 22 , or Ccycloalkyl group.25. A method for producing a dehydrogenation reaction product claim 22 , comprising the step of:{'claim-ref': {'@idref': 'CLM-00024', 'claim 24'}, 'subjecting an organic compound to a dehydrogenation reaction in the presence of the catalyst for dehydrogenation reaction according to .'} The present invention relates to a ligand, a metal complex comprising the ligand, and a reaction (specifically, ...

NOVEL TRANSITION METAL COMPLEXES, THEIR PREPARATION AND USE

Novel transition metal complexes are provided which represent viable catalysts for a broad variety of reactions such as hydrogenation reactions and metathesis reactions. Novel preparation processes are made available via unprecedented routes inter alia not involving structures according to Grubbs I or Grubbs II catalysts. 3. The complex according to claim 2 , wherein in general formula (I)M means Ru;X means O or S;{'sup': 2', '2', '2, 'sub': 1', '6', '5', '6', '6', '14, 'D means S, O, PR, or NRwith Rmeaning straight chain or branched C-Calkyl, C-Ccycloalkyl, or C-Caryl.'}Y means 1,2-ethylene or 1,2-phenyl;R means phenyl with none, 1, 2, 3, 4, or 5 substituents selected from the group consisting of F, Cl, Br, and I;{'sup': 1', '6', '7', '4', '5, 'sub': 3', '3', '3', '3', '2', '3', '3', '6', '4', '3', '3', '6', '4', '3', '6', '4', '3', '3', '2', '6', '4', '3', '3', '3', '3', '2', '3', '3', '3', '3', '3', '3', '6', '24', '1', '10', '6', '10', '6', '10, 'Lis selected from the group consisting of PPh, P(p-Tol), P(o-Tol), PPh(CH), P(CF), P(p-FCH), P(p-CFCH), P(CH—SONa), P(CHCH—SONa), P(isopropyl), P(CHCH(CHCH)), P(cyclopentyl), P(cyclohexyl), P(neopentyl), P(neophyl), and an N-heterocyclic carbene ligand of general formulae (IM-a) or (IM-b), wherein Rand Rare identical or different and represent i-propyl, neopentyl, adamantyl, mesityl or 2,6-diisopropylphenyl, and Rand Rare identical or different and represent hydrogen, C-C-aryl, straight-chain or branched C-C-alkyl, or together with the carbon atoms to which they are bound form a C-Ccycloalkyl or C-Caryl substituent;'}Z means B, Al, Ga, or In;{'sup': '1', 'Rare identical or different and represent F, Cl, Br, or I;'}{'sup': '1', 'Xmeans F, Cl, Br, or I;'}{'sup': '2', 'sub': '3', 'Lrepresents CHCN, pyridine or tetrahydrofurane; and'}n is either 0 or 1.10. (canceled)11. (canceled)12. A process for preparing compounds using the complex according to claim 2 , the process comprising subjecting a starting compound to a ...

Novel ruthenium complex and process for producing optically active alcohol compound using same as catalyst

The present invention provides a novel ruthenium complex which has an excellent catalytic activity in terms of reactivity for an asymmetric reduction of a carbonyl compound and enantioselectivity, a catalyst using the ruthenium complex, and a method for preparing optically active alcohol compounds using the ruthenium complex. The present invention relates to a ruthenium complex having a ruthenacycle structure, a catalyst for an asymmetric reduction consisting of the ruthenium complex, and a method for preparing optically active alcohol compounds using the ruthenium complex.

NOVEL RUTHENIUM COMPLEXES AND THEIR USES IN PROCESSES FOR FORMATION AND/OR HYDROGENATION OF ESTERS, AMIDES AND DERIVATIVES THEREOF

The present invention relates to novel Ruthenium complexes and related borohydride complexes, and their use for (1) hydrogenation of amides (including polyamides) to alcohols and amines; (2) preparing amides from alcohols with amines (including preparing polyamides (e.g., polypeptides) by reacting dialcohols and diamines or by polymerization of amino alcohols); (3) hydrogenation of esters to alcohols (including hydrogenation of cyclic esters (lactones), cyclic di-esters (di-lactones) or polyesters); (4) hydrogenation of organic carbonates (including polycarbonates) to alcohols and of carbamates (including polycarbamates) or urea derivatives to alcohols and amines; (5) dehydrogenative coupling of alcohols to esters; (6) hydrogenation of secondary alcohols to ketones; (7) amidation of esters (synthesis of amides from esters and amines); (8) acylation of alcohols using esters; (9) coupling of alcohols with water to form carboxylic acids; and (10) dehydrogenation of beta-amino alcohols to form pyrazines. The present invention further relates to novel uses of certain pyridine Ruthenium complexes. 4. The process according to claim 1 , wherein Xand/or Xare absent claim 1 , and the pyridyl or bipyridy moiety is unsubstituted.5. The process according to claim 1 , wherein Lis phosphine (PRR).13. The process according to claim 10 , wherein Xand/or Xare absent claim 10 , and the pyridyl or bipyridy moiety is unsubstituted.14. The process according to claim 10 , wherein Lis phosphine (PRR).16. The process of claim 10 , for preparing an amide from amine and an alcohol claim 10 , wherein the process is for preparing a polypeptide or a cyclic dipeptide claim 10 , and wherein the primary or secondary amine and the primary alcohol are a beta-aminoalcohol. This application is a Divisional Application from U.S. application Ser. No. 14/702,641 filed May 1, 2015, which is a Divisional Application from U.S. application Ser. No. 13/880,328 filed Jun. 11, 2013 now U.S. Pat. No. 9,045,381, ...

Catalysts and methods of making the same

Catalysts including at least one microporous material (e.g., zeolite), an organosilica material binder, and at least one catalyst metal are provided herein. Methods of making the catalysts, preferably without surfactants and processes of using the catalysts, e.g., for aromatic hydrogenation, are also provided herein.

CATALYST BASED ON CATECHOLAMINE AND ITS USE IN A HYDROTREATMENT AND/OR HYDROCRACKING PROCESS

The invention concerns a catalyst comprising a support based on alumina or silica or silica-alumina, at least one element selected from group VIII and/or group VIB, and at least one catecholamine. The invention also concerns the process for the preparation of said catalyst and its use in a hydrotreatment and/or hydrocracking process. 1. A catalyst comprising a support based on alumina or silica or silica-alumina , at least one element selected from group VIII and/or group VIB , and at least one catecholamine.2. The catalyst as claimed in claim 1 , in which the catecholamine is selected from dopamine claim 1 , noradrenaline claim 1 , adrenaline and isoprenaline claim 1 , alone or as a mixture.3. The catalyst as claimed in claim 1 , in which the content of the element from group VIB is in the range 5% to 40% by weight claim 1 , expressed as the oxide of the metal from group VIB with respect to the total weight of catalyst claim 1 , and the content of the element from group VIII is in the range 1% to 10% by weight claim 1 , expressed as the oxide of the metal from group VIII with respect to the total weight of catalyst.4. The catalyst as claimed in claim 1 , further containing phosphorus claim 1 , the quantity of phosphorus being in the range 0.01% to 20% by weight claim 1 , expressed as POwith respect to the total weight of catalyst claim 1 , and the ratio of phosphorus to the element from group VIE in the catalyst being greater than or equal to 0.01.5. The catalyst as claimed in claim 1 , in which the quantity of catecholamine is in the range 1% to 40% by weight with respect to the weight of the support.6. The catalyst as claimed in claim 1 , further containing an organic compound other than catecholamine claim 1 , containing oxygen and/or nitrogen and/or sulphur.7. The catalyst as claimed in claim 6 , in which the organic compound is selected from a compound comprising one or more chemical functions selected from a carboxyl claim 6 , alcohol claim 6 , thiol claim 6 ...

PROCESS FOR THE PREPARATION OF HYDROCARBON SOLUBLE ORGANOMETALLIC CATALYSTS

The instant disclosure provides a process for synthesis of compound of Formula: 1. A process for synthesis of compound of Formula:{'br': None, 'sub': a', 'b, 'sup': 'z+', 'X-M-Y,'}{'sup': z+', '−', '−', 'z+, 'sub': c', 'd', '1-16', '5-22', '1-16', '3-12', '1-20', '1-20', '1-16', '5-22', '1-16', '3-12', '1-20', '1-20', '1-16', '5-22', '1-16', '3-12', '1-20', '1-20', '1-16', '5-22', '1-16', '3-12', '1-20', 'a', 'b, 'wherein M is a transition metal ion, wherein z is in the range of 1-9; X and Y are anions of Formula R1 (COO), and R2(COO)respectively, wherein ‘c’ and ‘d’ are independently in the range of 1-2; when ‘c’ is 1, R1 is selected from the group consisting of Calkyl, Caryl, Chaloalkyl, Ccycloalkyl, Cheteroaryl, and Cheterocyclyl; when ‘c’ is 2, R1 is selected from the group consisting of Calkanediyl, Carylene, Chaloalkanediyl, Ccycloalkanediyl, Cheteroarenediyl, Cheterocyclicdiyl; when ‘d’ is 1, R2 is selected from the group consisting of Calkyl, Caryl, Chaloalkyl, Ccycloalkyl, Cheteroaryl, and Cheterocyclyl; when ‘d’ is 2, R2 is selected from the group consisting of Calkanediyl, Carylene, Chaloalkanediyl, Ccycloalkanediyl, Cheteroarenediyl, 01-20 heterocyclicdiyl; ‘a’ and ‘b’ are in the range of 0-9, wherein ‘a’ and ‘b’ have values such that X-M-Yis a neutral molecule;'}{'sub': c', 'd, 'the process comprising the steps of: (a) contacting (i) a transition metal salt of Formula M-S, wherein M is a transition metal and S is a ligand selected from the group consisting of nitrate, sulfate, chloride, sulfite, and nitrite; (ii) at least one carboxylate salt selected from the group consisting of salts of R1 (COOH)and salts of R2(COOH); (iii) water; and (iv) at least one organic solvent to obtain a first mixture is carried out at a temperature of 40° C.; and (b) stirring the first mixture to obtain the compound.'}2. The process as claimed in claim 1 , wherein (a) the transition metal salt to the at least one carboxylate salt molar ratio in the first mixture is in the ...

HYDROGENATION AND DISPROPORTIONATION CATALYSIS

Improved catalytic methods are disclosed. The methods include both hydrogenation and disproportionation catalysis. While the reaction conditions for hydrogenation and disproportionation differ, the catalysts disclosed herein can be used for either process. In certain aspects, the methods utilize a catalyst: CpM(N—N)L; wherein Cp is a substituted or unsubstituted cyclopentadienyl ligand; wherein M is selected from the group consisting of Ir and Rh; wherein N—N is a substituted or unsubstituted bidentate ligand selected from the group consisting of a bipyridine ligand and a phenanthroline ligand; wherein n is 0 or 1; and wherein when n is 1 L is selected from the group consisting of an anion and a molecule of a solvent. 2. A method of hydrogenating a substrate , comprising exposing the substrate and a catalyst to hydrogen gas , wherein the catalyst comprises:{'br': None, 'sub': 'n', 'CpM(N—N)L;'}wherein Cp is a substituted or unsubstituted cyclopentadienyl ligand;wherein M is selected from the group consisting of Ir and Rh;wherein N—N is a substituted or unsubstituted bidentate ligand selected from the group consisting of a bipyridine ligand and a phenanthroline ligand;wherein n is 0 or 1; andwherein when n is 1 L is selected from the group consisting of an anion and a molecule of a solvent.325-. (canceled)27. A method of forming methanol and methyl formate , comprising contacting formic acid with a catalyst comprising:{'br': None, 'sub': 'n', 'CpM(N—N)L;'}wherein Cp is a substituted or unsubstituted cyclopentadienyl ligand;wherein M is selected from the group consisting of Ir and Rh;wherein N—N is a substituted or unsubstituted bidentate ligand selected from the group consisting of a bipyridine ligand and a phenanthroline ligand;wherein n is 0 or 1; andwherein when n is 1 L is selected from the group consisting of an anion and a molecule of a solvent.28. The method of claim 26 , wherein the contacting step takes place under acidic conditions.2932-. (canceled)33. The ...

BIOLOGICALLY APPLICABLE WATER-SOLUBLE HETEROGENEOUS CATALYSTS FOR PARA-HYDROGEN INDUCED POLARIZATION

A heterogeneous catalyst composition for para-hydrogen induced polarization includes ligand-capped nanoparticles dispersed in water. The ligand-capped nanoparticles include metal nanoparticles that are surface functionalized with organic ligands, a molecular weight of the organic ligands is no greater than 300 g/mol, and the organic ligands each includes multiple binding moieties as coordinates sites for binding to a nanoparticle surface. 1. A heterogeneous catalyst composition for para-hydrogen induced polarization , comprising ligand-capped nanoparticles dispersed in water ,wherein the ligand-capped nanoparticles include metal nanoparticles that are surface functionalized with organic ligands, a molecular weight of the organic ligands is no greater than 300 g/mol, and the organic ligands each includes multiple binding moieties as coordinates sites for binding to a nanoparticle surface.2. The composition of claim 1 , wherein a surface coverage of the metal nanoparticles by the organic ligands is at least 4.2 ligands per nm.3. The composition of claim 1 , wherein a surface coverage of the metal nanoparticles by the organic ligands is at least 8 ligands per nm.4. The composition of claim 1 , wherein the molecular weight of the organic ligands is no greater than 250 g/mol.5. The composition of claim 1 , wherein the molecular weight of the organic ligands is no greater than 200 g/mol.6. The composition of claim 1 , wherein the organic ligands are amino acids.7. The composition of claim 1 , wherein the organic ligands are cysteine.8. The composition of claim 1 , wherein the organic ligands each includes a sulfhydryl group and an amino group as the binding moieties.9. The composition of claim 1 , wherein the organic ligands each further includes at least one hydrophilic moiety.10. The composition of claim 9 , wherein the hydrophilic moiety is a carboxyl group.11. The composition of claim 1 , wherein the metal nanoparticles are platinum nanoparticles.12. The composition ...

RUTHENIUM- OR OSMIUM-BASED COMPLEX CATALYSTS

The present invention provides novel ruthenium or osmium based complex structures with a unique combination of ligands comprising a Schiff-base type ligand, a N-heterocyclic carbene ligand and a CO ligand which can be prepared according to two different routes involving easily accessible starting materials and which represent excellent catalysts for hydrogenating unsaturated compounds, oligomers and polymers, in particular at unforeseeably low temperatures. 2. The complexes of general formula (I) according to claim 1 ,wherein:M is ruthenium;Y is H or Cl;{'sup': 1', '2', '3', '4, 'claim-text': [{'sub': '2', 'H; NO; F, Cl, or Br; or'}, {'sub': 1', '8, 'straight chain or branched, substituted or unsubstituted C-C-alkyl, more preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, and tert.-butyl; or'}, {'sub': 5', '8, 'substituted or unsubstituted C-C-cycloalkyl, more preferably cyclopentyl, cyclohexyl or cycloheptyl; or'}, {'sub': 6', '14', '6', '10, 'substituted or unsubstituted C-C-aryl, preferably C-C-aryl, more preferably phenyl, which aryl group, more preferably phenyl, is either unsubstituted or contains 1, 2, 3, 4 or 5 identical or different substituents; or'}, {'sup': 7', '7', '7', '7', '7', '7, 'sub': 3', '3', '2', '3', '1', '14', '1', '8, 'OR, OC(═O)R, CO(═O)R, SOR, SON(R)or SONa wherein Rrepresents H, straight chain or branched, substituted or unsubstituted C-C-alkyl, preferably C-C-alkyl, more preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, or tert.-butyl;'}], 'R, R, R, and Rare identical or different and represent'}{'sup': '5', 'claim-text': [{'sub': 1', '14', '1', '8, 'straight chain or branched, substituted or unsubstituted C-C-alkyl, preferably C-C-alkyl, more preferably methyl, ethyl, n-propyl, i-propyl, n-butyl, i-butyl, or tert.-butyl; or'}, {'sub': 3', '10', '5', '8, 'substituted or unsubstituted C-C-cycloalkyl, preferably C-C-cycloalkyl, more preferably cyclopentyl, cyclohexyl or cycloheptyl; or'}, {'sub': 6', '14', '6', ' ...

CATALYST COMPOSITIONS AND THEIR USE FOR HYDROGENATION OF NITRILE RUBBER

This invention relates to novel catalyst compositions based on ruthenium or osmium carbene-complex catalysts, pref. of the Grubbs-I, -II or -III type or fluorenylidene analogues thereof, and terminal olefins, pref. enol ethers such as ethyl vinyl ether (EVE or VEE) as co-catalysts and to a process for selectively hydrogenating nitrile rubbers in the presence of such catalyst compositions, pref. with a preceding metathesis step using the same complex catalyst as in the hydrogenation step. 1. A catalyst composition obtainable by contacting a complex catalyst based on ruthenium or osmium as central metal and bearing at least one ligand which is bound to the ruthenium or osmium central metal in a carbene-like fashion with at least one co-catalyst in a molar ratio of the complex catalyst to the co-catalyst in a range of from 1:(20-550) wherein the co-catalyst must contain at least one vinyl group.2. The catalyst composition according to wherein the co-catalyst has the general formula (1){'br': None, 'sub': '2', 'CH═CRR′\u2003\u2003(1)'}in which R and R′ are identical or different and shall meanhydrogen or{'sup': 1', '1', '2', '2', '2', '3', '4, 'sub': 2', '2', 'n', 'm', '2', 'n', 'm', '2', '2', 'p', '2, 'claim-text': wherein', {'sup': '2', 'X is identical or different and means oxygen (O) or NR'}, {'sup': '2', 'Rare identical or different and represent H, alkyl, cycloalkyl, alkenyl, alkynyl, aryl, or heteroaryl,'}, {'sup': '3', 'sub': 1', '5', '2', 'n', '2, 'Rare identical or different and represent C-Calkyl or —(CH)—O—CH═CH,'}, {'sup': '4', 'sub': 2', 'p', '2, 'Rrepresents (CH)—O—CH═CH,'}, 'n is in the range of from 1 to 5,', 'm is in the range of from 1 to 10,', 'p is in the range of from 0 to 5,', {'sup': 1', '1', '2', '2, 'sub': 2', 'q, 'where in the alternative, if R and R′ both represent a group OR, both Rmay be linked to each other and together represent a divalent group —(C(R))— with q being 2, 3 or 4 and Rbeing identical or different and having the above defined ...

Selective hydrogenation methods and catalysts

The present disclosure relates to methods for selectively hydrogenating acetylene, to methods for starting up a selective hydrogenation reactor, and to hydrogenation catalysts useful in such methods. In one aspect, the disclosure provides a method for selectively hydrogenating acetylene, the method comprising contacting a catalyst composition with a process gas. The catalyst composition comprises a porous support, palladium, and one or more ionic liquids. The process gas includes ethylene, present in the process gas in an amount of at least 20 mol. %; and acetylene, present in the process gas in an amount of at least 1 ppm. At least 90% of the acetylene present in the process gas is hydrogenated, and the selective hydrogenation is conducted without thermal runaway. Notably, the process gas is contacted with the catalyst at a gas hourly space velocity (GHSV) based on total catalyst volume in one bed or multiple beds of at least 7,100 h−1.

Selective Hydrogenation Catalyst and Methods of Making and Using Same

A method of making a selective hydrogenation catalyst comprising contacting a support with a palladium-containing compound to form a supported-palladium composition; contacting the supported-palladium composition with an organophosphorus compound and a weak acid to form a catalyst composition; and reducing the catalyst composition to form the catalyst. A method of making a selective hydrogenation catalyst comprising contacting an alumina support with a palladium-containing compound to form a supported-palladium composition; contacting the supported-palladium composition with silver nitrate and potassium fluoride to form a mixture; contacting the mixture with an organophosphorus compound and a weak acid to form a catalyst precursor; and reducing the catalyst precursor to form the catalyst. 1. A method of making a selective hydrogenation catalyst comprising:contacting a support with a palladium-containing compound to form a supported-palladium composition;contacting the supported-palladium composition with an organophosphorus compound and a weak acid to form a selective hydrogenation catalyst composition; andreducing the selective hydrogenation catalyst composition to form the selective hydrogenation catalyst.2. The method of wherein the organophosphorus compound is represented by the general formula (R)(OR′)P═O claim 1 , wherein x and y are integers ranging from 0 to 3 and x plus y equals 3 claim 1 , wherein each R is hydrogen claim 1 , a hydrocarbyl group claim 1 , or combinations thereof; and wherein each R′ is a hydrocarbyl group3. The method of wherein the organophosphorus compound comprises a phosphine oxide claim 1 , a phosphinate claim 1 , a phosphonate claim 1 , a phosphate claim 1 , or combinations thereof.4. The method of wherein the organophosphorus compound is a product of an organophosphorus compound precursor represented by the general formula of (R)(OR′)P claim 1 , wherein x and y are integers ranging from 0 to 3 and x plus y equals 3 claim 1 , wherein ...

PROCESS FOR PREPARING A CATALYST BASED ON A GROUP VIII METAL AND CONTAINING SILICON, AND A PROCESS OF SELECTIVE HYDROGENATION IMPLEMENTING SAID CATALYST

A process for preparing a selective hydrogenation catalyst is described, wherein is provided a catalyst precursor, comprising at least one group VIII metal in the metallic form, and at least one support formed of at least one oxide, characterised in that a step is performed of contacting the said catalyst precursor in the metallic form, in the liquid phase and in the presence of a reducing and/or inert atmosphere, with a non-polar solvent containing a silicon compound, the said silicon compound is selected from the silanes containing at least one Si—H bond and at least one Si—C bond, the silanols and the cyclic siloxanes. 1. A Process for preparing a selective hydrogenation catalyst comprising , contacting a catalyst precursor in the metallic form , in the liquid phase and in the presence of a reducing and/or inert atmosphere , with a non-polar solvent containing a silicon compound , a silicon compound is selected from the silanes containing at least one Si—H bond and at least one Si—C bond , the silanols and the cyclic siloxanes , wherein the catalyst precursor , comprises at least one group VII metal in the metallic form and at least one support formed of at least one oxide.2. A process according to claim 1 , wherein the group VIII metal is palladium or nickel.3. A process according to claim 1 , wherein the support is formed of at least one simple oxide selected from alumina claim 1 , silica claim 1 , titanium oxide claim 1 , cerium oxide and zirconium dioxide.4. A process according to claim 1 , wherein the non-polar solvent is selected from an aliphatic hydrocarbon solvent claim 1 , a cyclic hydrocarbon solvent claim 1 , an aromatic hydrocarbon solvent claim 1 , a partially saturated gasoline claim 1 , a partially hydrogenated effluent derived from a selective hydrogenation process claim 1 , or a mixture of these solvents.5. A process according to claim 1 , wherein the silicon compound is selected from the silanes corresponding to the formula SiHR claim 1 , ...

Vertically aligned mesoporous thin film, method of manufacturing the same, and catalytic application thereof

This invention relates to a vertically aligned mesoporous silicate film with site-selective metal deposition from a single polymeric precursor and to diverse catalytic applications thereof. There is an innovative approach of a single precursor to manufacture a vertically aligned mesoporous silicate thin film having high thermal and chemical resistance on a large-area silicon wafer (2 cm×3 cm). A precisely designed organic-inorganic block copolymer (BCP) polyethyleneoxide-ss-polyvinylcyclicsilazane (PEO-ss-PVCSZ) with a disulfide bridge that is chemically cleavable is newly synthesized as the single precursor for an oriented silicate nanoporous film, and using such a precursor, solvent annealing, self-assembling, block cleaving treatment, and then hydrolysis conversion of a polymer into a siliceous phase at room temperature are carried out, thus directly forming a mesostructure on the substrate.

METHOD FOR REDUCTION OF ORGANIC MOLECULES

A method for the reduction organic molecules comprising a Ruthenium-Triphosphine complex with aromatic ligands at the phosphors which are ortho or meta substituted. 1. A method for the reduction of organic molecules , comprising the step ofa) hydrogenating at least one organic molecule in the presence of a Ruthenium-Triphosphine-complex whereby the triphosphine-complex comprises at least one aryl and/or heteroaryl moeity bound to a phosphine which is substituted in ortho and/or meta position to the phosphine wherein the organic molecules are selected from the group consisting of carboxylic acids, carbonic acids, derivatives of carboxylic acids and derivatives of carbonic acids.2. The method according to claim 1 , wherein the Ruthenium-Triphosphine-complex comprises a phosphororganic compound where two or all three phosphors have an aryl and/or heteroaryl moeity which is substituted in ortho and/or meta position to the phosphine bound thereto.4. The method according to claim 1 , wherein step a) is performed under acidic conditions.5. The method according to claim 1 , wherein step a) is performed under acidic conditions whereby the initial concentration of acid is ≥0.5 to ≤20 times the concentration of Ruthenium in mol:mol.6. The method according to claim 5 , wherein step a) is performed under acidic conditions whereby the acid is a sulfonic acid.7. The method according to claim 1 , wherein step a) is carried out at an initial hydrogen pressure of ≥1 bar.8. The method according to claim 1 , wherein step a) is carried out in a dipolar protic or aprotic solvent or in CO.9. The method according to claim 6 , wherein the sulfonic acid is selected from the group consisting of methanesulfonic acid claim 6 , trifluoromethanesulfonic acid claim 6 , p-toluenesulfonic acid claim 6 , p-bromobenzosulfonic acid claim 6 , p-nitrobenzosulfonic acid claim 6 , sulfuric acid claim 6 , hydrochloric acid claim 6 , hydrofluoric acid claim 6 , trifluoroacetic acid claim 6 , perchloric acid ...

DUAL SITE CATALYST FOR MILD, SELECTIVE NITRILE REDUCTION

A ruthenium bis(pyrazolyl)borate scaffold that enables cooperative reduction reactivity in which boron and ruthenium centers work in concert to effect selective nitrile reduction is provided. The pre-catalyst compound [κ-(1-pz)HB(N═CHCH)]Ru(cymene) TfO (pz=pyrazolyl) was synthesized using readily-available materials through a straightforward route, thus making it an appealing catalyst for a number of reactions.

METAL COMPLEX INCLUDING TRIDENTATE AMINODICARBENE LIGAND AND HYDROGENATION REDUCTION METHOD USING SAME

The use of a metal complex containing a ruthenium ion or an osmium ion, and a tridentate aminodicarbene ligand, the tridentate aminodicarbene ligand having one secondary amino group and two specific heterocyclic carbene groups sandwiching the amino group, enables hydrogenation reduction of carbonyl compounds, such as ketones, carboxylic acid esters, lactones, carboxylic acid amides, and lactams, and imine compounds under relatively mild conditions to produce corresponding alcohols, amines, and the like in a high yield with high catalytic efficiency. The metal complex is obtained by a method comprising steps of reacting a specific metal compound with a specific aminodicarbene precursor and subsequently reacting a specific compound. Reduction of a carbonyl compound or an imine compound in the presence of this metal complex using a hydrogen donor makes it possible to reduce the carbonyl compound or imine compound by hydrogenation. 2. The metal complex according to claim 1 , wherein Rto Rare identical or different and each independently represents hydrogen claim 1 , halogen claim 1 , optionally substituted alkyl claim 1 , optionally substituted cycloalkyl claim 1 , optionally substituted aryl claim 1 , optionally substituted heterocyclic claim 1 , optionally substituted alkoxy claim 1 , or optionally substituted aryloxy claim 1 , or{'sup': 1', '2', '2', '3, 'Rand R, and/or Rand R, taken together, form optionally substituted alkylene, optionally substituted alkenylene, or optionally substituted oxyalkylene; and'}{'sup': 4', '8, 'Rto Rare identical or different and each independently represents hydrogen, halogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl, optionally substituted heterocyclic, optionally substituted alkoxy, or optionally substituted aryloxy, or'}{'sup': 5', '6', '7', '8, 'Rand R, and/or Rand R, taken together, form optionally substituted alkylene, optionally substituted alkenylene, or optionally substituted ...

PREPARATION AND USE OF COPPER CONTAINING HYDROGENATION CATLYST

The invention relates to a process for preparing a catalyst, which comprises: mixing a copper salt containing solution with a silicate salt containing composition resulting in a precipitated solid; and subjecting the precipitated solid to a temperature in the range of from 150 to 500° C. Further, the invention relates to a copper containing catalyst obtainable by said process. Still further, the invention relates to a hydrogenation process wherein such copper containing catalyst is used, more in particular a process wherein methyl phenyl ketone is hydrogenated into methyl phenyl carbinol. 1. A process for preparing a catalyst , which comprises:mixing a copper salt containing solution with a silicate salt containing composition resulting in a precipitated solid; andsubjecting the precipitated solid to a temperature in the range of from 150 to 500° C.2. The process according to claim 1 , wherein the silicate salt comprises an alkali metal silicate salt claim 1 , and/or an earth alkaline metal silicate salt.3. The process according to claim 2 , wherein the silicate salt comprises an alkali metal silicate salt and wherein the precipitated solid is mixed with an earth alkaline metal silicate salt.4. The process according to claim 1 , wherein an earth alkaline metal silicate salt claim 1 , preferably a calcium silicate salt:is mixed with the copper salt containing solution and/or the silicate salt containing composition before and/or during mixing the copper salt containing solution with the silicate salt containing composition; and/oris mixed with the precipitated solid, resulting from mixing the copper salt containing solution with the silicate salt containing composition, before subjecting the mixture thus obtained to a temperature in the range of from 150 to 500° C.; and/oris mixed with the thermally treated precipitated solid, resulting from subjecting the precipitated solid to a temperature in the range of from 150 to 500° C., with the proviso that the mixture thus ...

Iron catalysts with unsymmetrical pnn'p ligands

The present invention relates to catalytic materials for hydrogenation or asymmetric hydrogenation. In particular, the invention relates to iron (II) complexes containing unsymmetrical tetradentate diphosphine (PNN′P) ligands with two different nitro gen donor groups useful for catalytic transfer hydrogenation or asymmetric transfer hydrogenation of ketones, aldehydes and imines.

CHIRAL SPIRO PHOSPHORUS-NIROGEN-SULPHUR TRIDENTATE LIGAND, PREPARATION METHOD AND APPLICATION THEREOF

The present invention relates to a chiral spiro phosphine-nitrogen-sulfur (P—N—S) tridentate ligand, preparation method and application thereof. The P—N—S tridentate ligand is a compound represented by Formula I or Formula II, their racemates, optical isomers, or catalytically acceptable salts thereof. The ligand has a primary structure skeleton characterized as a chiral spiro indan skeleton structure with a thio group. The chiral spiro phosphine-nitrogen-sulfur tridentate ligand can be synthesized by reacting racemic or optical active compound 7-diary/alkyl phosphine-7′-amino-1,1′-spiro-dihydro-indene compound having a spiro-dihydro-indene skeleton as the starting material. The chiral spiro P—N—S tridentate ligand being complex with transition metal salt can be used in an asymmetric catalytic hydrogenation reaction for catalyzing carbonyl compound. In particular, in asymmetric hydrogenation reaction process, being complex with iridium for catalyzing β-alkyl-β-keto ester can obtain a high catalytic activity (a catalyst amount of 0.0002% mol) and high enantioselectivity (up to 99.9% ee) result. So the present invention has a practical value for industrial and commercial production. 4. A method for synthesizing the chiral spiro phosphine-nitrogen-sulfur tridentate ligand according to claim 2 , wherein claim 2 , comprising the following steps: the compound of Formula 1 is firstly reacted with the compound of Formula 2 (X is neither H nor OH) in a reactor for 2˜24 hours in the presence of an organic solvent and an alkali to obtain the compound shown as Formula 3; the compound of Formula 3 is then reduced to obtain the chiral spiro phosphine-nitrogen-sulfur tridentate ligand having the structure of Formula I; or the compound of Formula 1 is reacted with the compound of Formula 2 (X is H) in a reactor for 2˜24 hours in the presence of organic solvent and reducing agent directly to obtain the chiral spiro phosphine-nitrogen-sulfur tridentate ligand having the structure of ...