СПОСОБ ПОЛУЧЕНИЯ УКСУСНОЙ КИСЛОТЫ

Изобретение относится к усовершенствованному способу повышения скорости реакции в отсутствии промотора рутения и снижения токсичности каталитической системы при получении уксусной кислоты карбонилированием метанола и/или его реакционноспособного производного моноксидом углерода в по меньшей мере одной зоне реакции карбонилирования, содержащей жидкую реакционную композицию, включающую иридиевый катализатор карбонилирования, метилиодидный сокатализатор, воду в ограниченной концентрации, уксусную кислоту, метилацетат и в качестве промоторов индий и рений. 15 з.п. ф-лы, 2 табл., 2 пр.

КАРБОКСИЛАТНЫЕ СОЕДИНЕНИЯ БЛАГОРОДНЫХ МЕТАЛЛОВ Ir, Ru, Rh, Pd, Pt И Au, ОБЛАДАЮЩИЕ ВЫСОКОЙ КАТАЛИТИЧЕСКОЙ ЭФФЕКТИВНОСТЬЮ

Изобретение относится к способу получения карбоксилатных соединений благородного металла или их растворов. Благородный металл выбран из группы, состоящей из рутения, иридия, платины, палладия, родия и золота. Металл плавят с пероксидом щелочноземельного металла, после чего плавленую массу растворяют в карбоновой кислоте или карбоновой кислоте, разбавленной протонным растворителем. Из получаемого в результате раствора ионы щелочноземельного металла удаляют в виде соли щавелевой кислоты или соли производного щавелевой кислоты. Карбоксилатные соединения благородного металла обладают высокой каталитической активностью, а способ их получения является простым. 6 н.п. ф-лы, 4 пр.

ЗАМЕЩЕННЫЕ ФЕРРОЦЕНИЛДИФОСФИНЫ В КАЧЕСТВЕ ЛИГАНДОВ ДЛЯ ГОМОГЕННЫХ КАТАЛИЗАТОРОВ ГИДРИРОВАНИЯ

Описаны соединения формулы I, ! , ! где R1 представляет собой фенил, R2 представляет собой диметиламиногруппу, и R представляет собой радикал формулы ! , ! где R3 представляет собой метил, R4 представляет собой Н или метоксил, которые являются лигандами для металлокомплексов, используемых как гомогенные катализаторы гидрирования прохиральных органических соединений, содержащих двойные связи, при использовании которых можно достичь очень высоких активности и производительности, а также энантиоселективности. 4 н. и 2 з.п. ф-лы.

ЗАМЕЩЕННЫЕ ФЕРРОЦЕНИЛДИФОСФИНЫ В КАЧЕСТВЕ ЛИГАНДОВ ДЛЯ ГОМОГЕННЫХ КАТАЛИЗАТОРОВ ГИДРИРОВАНИЯ

... 1. Соединение формулы I в виде практически чистых энантиомеров, где R1 представляет собой С1-С4алкил, С6-С10арил или С7-С11аралкил, R2 представляет собой нециклическую или циклическую вторичную аминогруппу, R представляет собой радикал формулы где R3 представляет собой С1-С4алкил или С1-С4алкоксил, и R4 представляет собой Н, С1 -С4алкил или С1-С4алкоксил. 2. Соединение по п.1, где R1 в соединении формулы I представляет собой фенил. 3. Соединение по п.1, где нециклическая вторичная аминогруппа R2 соответствует формуле R5R6N-, где R5 и R6 представляют собой независимо друг от друга C1 -С6алкил, С3-С8циклоалкил, С6-С10арил, или С7-С11аралкил, где циклоалкильные группы и арильные группы являются незамещенными, или замещенными С1-С4алкилом или С1-С4алкоксилом, или R5 и R6 вместе образуют тетраметилен, пентаметилен или 3-оксапентилен. 4. Соединение по п.3, где каждый из R5 и R6 представляет собой метил. 5. Соединение по п.1, где оба радикала R3 представляют собой метил, трет-бутил или метоксил ...

KATALYTISCHE ASYMMETRISCHE HYDRIERVERFAHREN

Neue Diphosphinverbindung, Zwischenprodukte für deren Herstellung, Übergangsmetallkomplex enthaltend die Verbindung als Ligand und Katalysator für asymmetrische Hydrierungen, welcher den Komplex enthält

Polymere phosphorhaltige Zusammensetzungen und deren Verwendung in Hydrocyanierungs-, Isomerisierungs- und Hydroformylierungs-Reaktionen

Aminosäurekomplexe und ihre Verwendung zur Herstellung von Olefinpolymerisaten

Aminosäurekomplex der allgemeinen Formel I, DOLLAR F1 wobei M ausgewählt wird aus Fe, Co, Ni, Pd, Pt oder Ir, vorzugsweise Ni, bedeutet; Verfahren zu ihrer Herstellung sowie Verwendung zur Polymerisation von Olefinen.

Optisch aktive Diphosphine, diese enthaltende Übergangsmetallkomplexe und ein Verfahren zur Darstellung einer optisch aktiven Verbindung, in dem diese Komplexe eingesetzt werden

Verfahren zur katalytischen Umsetzung olefinisch ungesättigter Verbindungen mit Wasserstoff und/oder Kohlenmonoxid

CHIRALE PHOSPHINE, DEREN KOMPLEXE MIT ÜBERGANGSMETALLEN UND DEREN VERWENDUNG IN ASYMMETRISCHEN SYNTHESEREAKTIONEN

VERFAHREN ZUR HERSTELLUNG EINES ALDEHYDS

Verwendung von molekulargewichtsvergrößerten Katalysatoren in einem Verfahren zur asymmetrischen kontinuierlichen Hydrierung, neue molekulargewichtsvergrößerte Liganden und Katalysatoren

Die vorliegende Erfindung richtet sich auf eine Verwendung von molekulargewichtsvergrößerter homogen löslicher Katalysatoren Verfahren zur asymmetrischen kontinuierlichen Hydrierung von C=C-, C=N- oder C=O-Doppelbindungen mittels molekulargewichtsvergrößerter homogen löslicher Katalysatoren in einem Membranreaktor. DOLLAR A Bisherige im Stand der Technik vorgeschlagene Hydrierverfahren liefen diskontinuierlich ab. Die kontinuierliche Fahrweise hilft dagegen Prozeßkosten zu sparen. DOLLAR A Angegeben werden auch neue molekulargewichtsvergrößerte Liganden und Katalysatoren.

Chirale Diphosphin-Verbindung, Zwischenprodukte zu ihrer Herstellung, Übergangsmetall-Komplexe davon und asymmetrischer Hydrierungskatalysator

A novel catalytic formulation and its preparation technical field

Polyamide preparation

... 1,145,286. Polyamide production. IMPERIAL CHEMICAL INDUSTRIES Ltd. 22 July, 1966 [30 April, 1965; 25 March, 1966], Nos. 18330/65 and 13442/66. Heading C3R. Linear fibre-forming polyamides are prepared by heating an aqueous liquid reaction mixture containing polyamide-forming ingredients under pressure in an apparatus which allows steam to escape, the lower zone of the wall of the reaction vessel below the final liquid level being maintained at a temperature above that of the reaction mixture for at least the latter part of the heating period and at the same time the upper zone of the wall being maintained at a temperature below that of the lower zone. The reaction mixture may be a 45-95% solution of hexamethylene diammonium adipate. The vessel may be one of those illustrated in Figs. 1 and 2 of the Provisional Specifications (not shown), i.e. it may comprise a vertical cylindrical vessel which has openings at the top and bottom but is otherwise completely surrounded by a heating jacket ...

AROMATIC CARBONATES

Improvements in and relating to catalysis

The invention relates to a process for the production of a straight chain aldehyde from an olefin comprising reacting said olefin in a liquid reaction medium with hydrogen and carbon monoxide in the presence of a complex of Rh(I) in solution in the said medium as catalyst and a heterogeneous co- catalyst comprising a catalytic metal (e.g. Ru, Rh, Pd, It, Pt or alloys thereof) deposited upon a solid particulate support.

Metal chelate complexes for foming oxidation catalyst.

A robust chelate complex is provided having formula (I) wherein M is a metal, preferably a transition metal; Z is an anionic donor atom, at least three of which are nitrogen, and the other is preferably nitrogen or oxygen; LI is a labile ligand; Ch,, Ch and Ch3, are oxidation resistant chelate groups which are the same or different and which form 5- or 6-membered rings -with the metal, and Ch^ is a chelate group having structure (a) wherein R, and R2_are the same or different and are preferably selected from the group consisting of hydrogen, halogen, methyl, and CF or when linked, a 5- or 6-membered ring cyclo substituent. The complex provides a stable, long-lived oxidation catalyst or catalyst activator.

Long-lived homogenous oxidation catalyst

Long-lived homogenous oxidation catalysts

Long-lived homogenous oxidation catalyst

PHOSPHINVERBINDUNGEN, ÜBERGANGSMETALLKOMLEXE WITH THE CONNECTIONS, WHICH WHEN LIGAND IN IT CONTAINING ARE, AND ASYMMETRICAL SYNTHESIS CATALYSTS WITH THESE COMPLEXES

STEREOSPEZIFI ISOMERIERUNG OF ALLYL AMINES USING IMMOBILIZED CHIRALEN PHOSPHO LIGANDS

VERFAHREN ZUR REGENERIERUNG UND ABTRENNUNG VON RHODIUM ODER IRIDIUM ENTHALTENDEN KATALYSATOREN

PROCEDURE FOR THE ASYMMETRICAL SYNTHESIS

PROCEDURE FOR THE PRODUCTION OPTICAL OF ACTIVE CARBONYLVERBINDUNGEN

CHIRALE PHOSPHINE, THEIR COMPLEXES WITH TRANSITION METALS AND THEIR USE IN ASYMMETRICAL SYNTHESIS REACTIONS

SELECTIVE, CATALYTIC AND THERMAL FUNCTIONALIZATION OF SECONDARY OR AROMATIC CH CONNECTIONS IN CYCLIC HYDROCARBONS

PROCEDURE FOR THE PRODUCTION OF NEW POLYMERS RHODIUM, IRIDIUM AND RUTHENIUM PHOSPHINKOMPLEXVERBINDUNGENUND THEIR USE

PROCEDURE FOR THE PRODUCTION OF MONO CARBONIC ACID ANHYDRIDES.

CATALYSTS

LIGAND FOR PNICOGENCHELATKOMPLEXE WITH A METAL THE VIIITH NEBENGRUPPE AND USE OF THE COMPLEXES AS CATALYSTS FOR HYDROFORMYLIERUNG, CARBONYLIERUNG, HYDROCYANIERUNG OR HYDROGENATION

CHIRALE LIGANDS, ITS TRANSITION METAL COMPLEXES AND THE APPLICATION OF THESE IN ASYMMETRICAL REACTIONS

PROCEDURE FOR THE PRODUCTION OF AMINES CATALYZED REDUCTIVE ONES THROUGH HOMOGENEOUS AMINIERUNG FROM CARBONYLVERBINDUNGEN

PROCEDURE FOR THE ASYMMETRICAL HYDROGENATION OF KETOCARBONSÄUREESTERN

PROCEDURE FOR THE PRODUCTION OF METAL COMPLEXES, THE HYDROXYALKOXYCARBONYLCYCLOPENTADIEN LIGANDS CONTAINING

PROCEDURE FOR CYCLOTRIMERISIERUNG OF ALKINES IN AQUEOUS SOLUTIONS

CHIRALE FERROCENE

HETERO ARYL ARYL DIPHOSPHINE AS CHIRALE LIGAND

SELECTIVE ONES, CATALYTI AND THERMAL INDUCED FUNCTIONALIZATION PRIMARY CH CONNECTIONS IN HYDROCARBONS

CHIRALER FIRM CATALYST, ITS PRODUCTION AND ITS USE TO HESRTELLUNG OF PRACTICAL ENANTIOMERENREINEN PRODUCTS

SULFONIERTE PHENYLPHOSPHANE ABSTENTION COMPLEX CONNECTIONS

SULFONIERTE PHENYLPHOSPHANE ABSTENTION COMPLEX CONNECTIONS

NEW ASYMMETRICAL PHOSPHIN LIGAND

BY A UNTIL PHOSPHORINAN DERIVATIVE AND CONNECTION SUITABLE FOR THE PRODUCTION OF A CARBONYLIERUNGS OF CATALYST SYSTEM

BY TRANSITION METAL COMPLEXES WITH CYCLIC CHIRALEN ASYMMETRICAL SYNTHESIS CATALYZED LIGANDS

CATALYTIC COMPOSITION FOR CARBONYLIERUNG WITH IRIDIUM AND PYRIDINE ATTITUDE POLYMERS

Process for preparing optically active 1-(p-methoxybenzyl)-1,2,3,4,5,6,7,8-octahydroisoquinoline

Diphosphines, preparation and uses thereof

ENANTIOSELECTIVE AMINATION AND ETHERIFICATION___________________

MIXTURES OF CHIRAL MONOPHOSPHORUS COMPOUNDS USED AS LIGAND SYSTEMS FOR ASYMMETRIC TRANSITION METAL CATALYSIS

Catalyst for asymmetric transfer hydrogenation

METALLIC CATALYSTS FOR CHEMO-, REGIO- AND STEREOSELECTIVE REACTIONS, AND CORRESPONDING PRECURSORS

LIGANDS FOR USE IN CATALYTIC PROCESSES

AROMATIC CARBONATES

Novel metal complex, method for producing same, and method for producing gamma-lactam compound using same

The present invention relates to a novel metal complex, a method for producing same, and a method for producing a gamma-lactam compound using same, and the metal complex according to the present invention is used as a catalyst for producing a gamma-lactam compound and can efficiently produce a gamma-lactam compound with an excellent yield and excellent selectivity.

Mesoscopic organopolysiloxane particles with chemically bound metallic compounds

Chiral diphosphines and their metal complexes

Process for preparing aldehydes

Chiral phosphorated ligands useful in catalysts

Process to prepare a terminal aldehyde

COMPLEX COMPOUNDS CONTAINING SULFONATED PHENYL PHOSPHANES

PROCESS FOR TRANSITION METAL-CATALYZED ASYMMETRIC HYDROGENATION OF ACRYLIC ACID DERIVATIVES, AND A NOVEL CATALYST SYSTEM FOR ASYMMETRIC TRANSITION METAL CATALYSIS

CATALYTIC MATERIAL AND METHOD FOR PREPARATION THEREOF

PROCEDE DE CARBONYLATION DES AMINES ET SYSTEMES CATALYTIQUES UTILISES

POLYMERIC DIPHOSPHINE LIGANDS FOR HOMOGENEOUSLY SOLUBLE HYDROGENATION CATALYSTS, PROCESS FOR THE PRODUCTION THEROF AND USE

Molecular weight-enlarged, homogeneously soluble ligands for hydrogenation catalysts comprising homochiral active centres of bis(3,4-diarylphosphinyl)pyrrolidines. Once transferred into catalysts, the ligands may advantageously be used in membrane reactors in semi- continuous or continuous organic syntheses. Process and use, catalysts.

CHIRAL PHOSPHINES, TRANSITION METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS

Chiral ligands and transition metal complexes based on such chiral ligands useful in asymmetric catalysis are dis-closed. The chiral ligands include chiral C1-C6 TunaPhos ligands. The ruthenium TunaPhos complex reduces ketones to the corre-sponding alcohols with 95-99.6 % enantioselectivity. The transition metal complexes of the chiral ligands are useful in asymmetric reactions such as asymmetric hydrogenation, hydride transfer, hydrosilylation, hydroboration, hydrovinylation, hydroformylation, hydrocarboxylation, isomerization, allylic alkylation, cyclopropanation, Diels- Alder reaction, Heck reaction, isomerization, Aldol reaction, Michael addition and epoxidation reactions.

CHIRAL LIGANDS, TRANSITION-METAL COMPLEXES THEREOF AND USES THEREOF IN ASYMMETRIC REACTIONS

... ²²²Chiral ligands and transition metal complexes based on such chiral ligands ²useful in asymmetric catalysis are disclosed. The chiral ligands include ²phospholanes, P, N ligands, N, N ligands, biphenols, and chelating phosphines. ²The ferrocene-based irridium (R,R)-f-binaphane complex reduces imines to the ²corresponding amines with 95-99.6 % enantioselectivity and reduces .beta.-²substituted-.alpha.-arylenamides with 95 % enantioselectivity. The transition ²metal complexes of the chiral ligands are useful in asymmetric reactions such ²as asymmetric hydrogenation of imines, asymmetric hydride transfer reactions, ²hydrosilylation, hydroboration, hydrovinylation, hydroformylation, allylic ²alkylation, cyclopropanation, Diels-Alder reaction, Heck reaction, ²isomerization, Aldol reaction, Michael addition and epoxidation reactions.² ...

PREPARATION OF 2-CYANOHEXANOIC ACID DERIVATIVES AND THE DERIVATIVES PREPARED BY THE PROCESS

PREPARATION OF 2-CYANOHEXANOIC ACID DERIVATIVES AND THE DERIVATIVES PREPARED BY THE PROCESS A process for the preparation of 2-cyanohexanoic acid derivative having the general formula: (I) wherein X and Y each represent a chlorine or bromine atom, each Hal represents a fluorine, chlorine or bromane atom and R1 and R2 each independently represent an alkyl group of one to four carbon atoms, which comprises reacting a pentenoic acid compound of the general formula: (II) wherein R1 and R2 have the same meaning as in the general formula I, with a tetrahalomethane of the general formula: CHal2XY (III) wherein Hal, X and Y have the same meaning as in the general formula I, in the presence of a catalyst and a solvent for the reactants, characterized in that the catalyst is a transition metal in a divided state belonging to Groups VIB, VIIB or VIII of the Periodic Table of the Elements or a carbonyl of such a transition metal. The 2-cyanohexanoic acid derivatives are useful as intermediates in the ...

ASYMMETRIC CATALYSIS

PROCESS FOR THE REGENERATION AND SEPARATION OF CATALYSTS OF THE FORMULAS RH OR IR(CO) (PR3)2 AND HRH OR IR (CO) (PR3)3

COMPOUND SUITABLE FOR USE AS A CATALYST OR FOR PRODUCING A CATALYST SYSTEM DERIVED FROM A BIS-PHOSPHORINANE

... .he invention relates to a compound of formula (I) wherein X represents a low alkylen group, an arylene group or an alkarylene group, L1 has formula (II) wherein Y1 represents oxygen, sulphur or N-R17, R11, R12, R13, R14, R15, R16, R17 independently represent hydrogen, alkyl or aryl, L2 has formula (III) wherein Y2 represents oxygen, sulphur or N-R27, R21, R22, R23, R24, R25, R26, R27 independently represent hydrogen, alkyl or aryl wherein L1 and L2 can be identical or different. The inventive compound is suitable for use as a catalyst or for producing a catalyst system.

DIPHOSPHINES, PREPARATION AND USES THEREOF

La présente invention a pour objet de nouvelles diphosphines de Formule (I) notamment utiles, sous leur forme optiquement active, à titre de ligands dans des complexes métalliques. La présente invention concerne également leurs utilisations comme produits intermédiaires dans la préparation de ligands sous une forme insoluble de type polymérique. L'invention vise également l'utilisation desdits ligands insolubles notamment dans la préparation de complexes métalliques destinés à la catalyse asymétrique.

POLYMERIC, PHOSPHOROUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, ISOMERIZATION AND HYDROFORMYLATION REACTIONS

A polymeric, phosphorus-containing composition derived from aryl to aryl coupling of a substituted 2,2'-dihydroxyl-1,1'-binaphthalene or a substituted 2,2'-dihydroxyl-1,1'-biphenylene and phosphonylated at the dioxyl of said structure with at least one diaryloxyphosphite [-P(-O-Ar)2], diarylphosphine [- P(Ar)2] and/or aryl,aryloxyphosphinite [-P(Ar)(-O-Ar)], where each Ar is individually phenyl, substituted phenyl, naphthyl, and substituted naphthyl, provided that the two Ar groups that are directly or indirectly bonded to the same phosphorus atom may be linked to each other by a linking unit selected from direct bond, alkylidene, secondary or tertiary amine, oxygen, sulfide, sulfone, and sulfoxide. Polymerization by aryl to aryl coupling is achieved by direct oxidative coupling of the binaphthalene or biphenylene, copolymerization with an aromatic comonomer, or copolymerization with an aldehyde. The phosphonylation may be performed prior to or after polymerization. The polymeric, phosphorus-containing ...

PRODUCTION OF OPTICALLY ACTIVE PHOSPHOLANES

The invention relates to phospholanes and diphospholanes of general formula (I), whereby R represents H, C1-C6-alkyl, aryl, alkyl aryl, SiR23, R2 represents alkyl or aryl, A represents H, C1-C6-alkyl, aryl, Cl, or (a), and B represents a binding link with 1-5 C-atoms between both P-atoms. The invention also relates to the use of said phospholanes and diphospholanes as a catalyst in asymmetric synthesis.

METHOD FOR THE PRODUCTION OF PRAZIQUANTEL AND PRECURSORS THEREOF

The present invention provides methods of preparing Praziquantel, in particular (R)-Praziquantel and analogues thereof in a stereoselective manner. One method involves asymmetric hydrogenation of the following intermediate compound (I) and subsequent cyclization.

NOVEL METAL COMPLEX, METHOD FOR PRODUCING SAME, AND METHOD FOR PRODUCING GAMMA-LACTAM COMPOUND USING SAME

The present invention relates to a novel metal complex, a method for producing same, and a method for producing a gamma-lactam compound using same, and the metal complex according to the present invention is used as a catalyst for producing a gamma-lactam compound and can efficiently produce a gamma-lactam compound with an excellent yield and excellent selectivity.

PROCESS FOR MAKING MONOCARBOXYLIC ANHYDRIDES

MIXTURES OF CHIRAL MONOPHOSPHORUS COMPOUNDS USED AS LIGAND SYSTEMS FOR ASYMMETRIC TRANSITION METAL CATALYSIS

The invention relates to certain chiral transition metal catalysts, to the metal of which at least two structurally different monophosphorus ligands are bonded, at least one of said monophosphorus ligands being chiral. Said chiral transition metal catalysts are suitable as catalysts for use in asymmetric transition metal-catalyzed reactions, providing better enantioselectivities than in cases where only one structurally defined ligand is used.

TOLUIC ACID

METHOD FOR THE PRODUCTION OF HYDROGEN FROM AMMONIA BORANE

The present disclosure relates to processes and methods of generating hydrogen via the hydrolysis or solvolyis of a compound of the formula (I), R1R2HNBHR3R4, using ligand-stabilized homogeneous metal catalysts.

CATALYST SUPPORTS AND TRANSITION METAL CATALYSTS SUPPORTEDTHEREON

FERROCENE DIPHOSPHINES AS LIGANDS FOR HOMOGENEOUS CATALYSTS

Compounds of formula I (see formula I) wherein R1 is C1-C8alkyl, phenyl or phenyl which is substituted by 1 to 3 C1- C4alkyl or C1-C4alkoxy groups; R2 and R3 are each independently of the other typically C1- C12alkyl, C5-C12cycloalkyl, phenyl, or C1-C4alkyl- or C1-C4alkoxy-substituted C5- C12cycloalkyl, or phenyl which is substituted by one to three identical or different members selected from the group consisting of C1-C4alkyl, C1-C4alkoxy or halogen; R10 and R11 are identical and are typically C1-C12alkyl, C5-C12cycloalkyl, C1- C4alkyl- or C1-C4alkoxy-substituted C5-C12cycloalkyl or phenyl which is substituted by 1 to 3 identical or different members selected from the group consisting of C1- C4alkyl, C1-C4alkoxy or halogen; or R10 and R11 are different and are C1-C12alkyl, C5- C12cyclo- alkyl, C1-C4alkyl- or C1-C4alkoxy-substituted C5-C12cycloalkyl, phenyl or phenyl which is substituted by 1 to 3 identical or different members selected from the group consisting of C1-C4alkyl, C1-C4alkoxy ...

COMPLEX COMPOUNDS CONTAINING SULFONATED PHENYL PHOSPHANES

METAL COMPLEXES WITH HETEROCYCLIC CARBENES

The invention relates to novel complexes of elements of groups 8, 9 ana lo of the periodic table with heterocyclic carbenes as ligands.

DIPHOSPHINES CONTAINING SILANE GROUPS, IMMOBILISED DIPHOSPHINES AND THE USE THEREOF AS HYDROGENATION CATALYSTS

Compounds of formula I wherein the groups (R1) 2P (CH2)m and (R1) 2P (CHz) n are in o- or m- position to each other and the substituents R1 are identical or different radicals, m and n are each independently of the other 0 or 1, R1 is linear or branched C1-C12alkyl, unsubstituted C5-C6cycloalkyl or C5-C6cycloalkyl which is substituted by C1-C4alkyl or C1-C4alkoxy, or is phenyl or benzyl, or both substituents R1 in a group (R1)2P together are o,o'-diphenylene, -R2-X- is a bond or -(C xH2x-O) y-, or X- is O- and R2 is C1-C6alkylene, x is an integer from 2 to 6 and y is an integer from 2 to 6, R3 is C2-C18alkylene, phenylene or benzylene, and R4 is C1-C6alkyl or phenyl, can be applied to solid carriers, such as silica gel or aerosils, and complexed with rhodium or iridium compounds. These materials are heterogeneous and separable catalysts for the asymmetrical hydrogenation of prochiral compounds containing carbon double bonds or carbon/hetero atom double bonds, for example ketones and imines ...

MESOSCOPIC ORGANOPOLYSILOXANE PARTICLES WITH CHEMICALLY BOUND METALLIC COMPOUNDS

The invention relates to organopolysiloxane particles which are cross-linked, comprise a single molecule, have chemically bound metallic compounds and an average diameter of from 5 to 200 nm and are soluble in at least one solvent chosen from dichloromethane, pentane, acetone, ethanol and water to at least 1 % by weight. At least 80 % of the particles have a diameter which deviates a maximum of 30 % from the average diameter. The organopolysiloxane particles can be used as catalysts.

TRANSFER HYDROGENATION PROCESS AND CATALYST

A catalytic transfer hydrogenation process is provided. The catalyst employe d in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. Preferred bidentate ligands are diamines and aminoalcohols, particularly those comprising chiral centres. Th e hydrogen donor is advantageously a secondary alcohol or a mixture of triethylamine and formic acid. The process can be employed to transfer hydrogenate ketones and imines, which are preferably prochiral. Catalysts for use in such a process are also provided.

LONG-LIVED HOMOGENOUS OXIDATION CATALYSTS

A robust chelate complex is provided having formula (I) wherein M is a metal, preferably a transition metal; Z is an anionic donor atom, at least three of which are nitrogen, and the other is preferably nitrogen or oxygen; L1 is a labile ligand; Ch1, Ch2 and Ch3 are oxidation resistant chelate groups which are the same or different and which form 5- or 6-membered rings with the metal, and Ch4 is a chelate group having structure (a) wherein R1 and R2 are the same or different and are preferably selected from the group consisting of hydrogen, halogen, methyl, and CF3 or when linked, a 5- or 6-membered ring cyclo substituent. The complex provides a stable, long-lived oxidation catalyst or catalyst activator.

LONG-LIVED HOMOGENOUS OXIDATION CATALYSTS

A robust chelate complex is provided having formula (I) wherein M is a metal , preferably a transition metal; Z is an anionic donor atom, at least three of which are nitrogen, and the other is preferably nitrogen or oxygen; L1 is a labile ligand; Ch1, Ch2 and Ch3 are oxidation resistant chelate groups which are the same or different and which form 5- or 6-membered rings with the metal, and Ch4 is a chelate group having structure (a) wherein R1 and R2 are the same or different and are preferably selected from the group consisting of hydrogen, halogen, methyl, and CF3 or when linked, a 5- or 6-membered ring cyclo substituent. The complex provides a stable, long-lived oxidation catalyst or catalyst activator.

TRANSITION METAL-CATALYZED REACTIONS BASED ON CHIRAL AMINE OXAZOLINYL LIGANDS

The invention is drawn to novel transition metal catalysts for the pratical synthesis of important chiral molecules. The transition metal catalysts comprise chiral ligands based on chiral amine oxazolinyl ligands. The invention includes methods of making the catalysts, and methods of performing reactions using the catalysts.

PROCEDE DE PREPARATION DE COMPOSES COMPLEXES DE METAUX DU VIIIEME GROUPE DE LA CLASSIFICATION PERIODIQUE ET PRODUITS ISSUS DE CE PROCEDE.

Verfahren zur Herstellung von synthetischen linearen faserbildenden Polyamiden

Process for the preparation of enantiomorphs of alpha-amino acid derivatives

Process for the preparation of organic complexes of transition metals

Supported metal catalysts

The present invention relates to supported metal catalysts, wherein the catalysts are modified by at least one amine, a method for the preparation thereof and hydrogenation processes utilising the supported metal catalysts.

Method for producing urethanes

The invention relates to a method for producing urethanes or ureas or mixtures of urethanes and ureas by oxidative carbonylation of organic amines in the presence of carbon monoxide, oxygen and a catalyst, where the catalyst used is a transition metal complex containing the structural feature: [Mn+(O˜N˜O)2−](n-2)+(L)m(Z−)n-2 and the method is carried out under halogen-free reaction conditions. The invention further relates to transition metal complexes containing said structural feature and also to the use of such transition metal complexes as catalysts in the production of urethanes or ureas or mixtures of urethanes and ureas.

DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF

Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside. 1. A method of peptide functionalization comprising:providing a reaction mixture including a Michael acceptor and a peptide; andcoupling the Michael acceptor with the peptide via a mechanism including decarboxylation.2. The method of claim 1 , wherein coupling of the peptide and the Michael acceptor provides a 1 claim 1 ,4-addition adduct.4. The method of claim 1 , wherein the peptide comprises at least three amino acids.5. The method of claim 1 , wherein the peptide comprises at least five amino acids.6. The method of claim 1 , wherein the peptide is a protein.7. The method of claim 1 , wherein decarboxylation occurs subsequent to formation of a carboxyl radical at a peptide residue.8. The method of claim 7 , wherein carboxyl radical formation is initiated by a single electron transfer (SET) process.9. The method of claim 8 , wherein the SET process is oxidative.10. The method of claim 8 , wherein the SET process is reductive.11. The method of claim 7 , wherein an α-amino radical is formed by the decarboxylation at the peptide residue.12. The method of claim 11 , wherein the α-amino radical undergoes conjugate addition with the Michael acceptor.13. The method of claim 8 , wherein the reaction mixture further comprises catalyst for initiating the SET process.14. The method of wherein the catalyst is transition metal catalyst.15. The method of claim 13 , wherein the catalyst is photoredox catalyst.16. The method of ...

BIPYRIDYL COMPOUND

There are provided a compound capable of being a novel ligand allowing regioselective borylation to be performed in the aromatic borylation reaction, and a catalyst using the same compound. There is provided a bipyridyl compound represented by a general formula (): (wherein A represents a single bond, a vinylene group or an ethynylene group; 2. The bipyridyl compound according to claim 1 , wherein A is a single bond.3. The bipyridyl compound according to claim 1 , wherein Ris a hydrogen atom claim 1 , a halogen atom claim 1 , an alkyl group having 1 to 10 carbon atoms claim 1 , an alkenyl group having 2 to 10 carbon atoms claim 1 , a cycloalkyl group having 3 to 7 carbon atoms claim 1 , an aryl group having 6 to 10 carbon atoms claim 1 , an aryloxy group having 6 to 10 carbon atoms claim 1 , an alkoxy group having 1 to 10 carbon atoms claim 1 , a Calkylamino group claim 1 , a di(Calkyl)amino group or a Calkoxycarbonyl group.4. The bipyridyl compound according to claim 1 , wherein Ris a hydrogen atom claim 1 , an optionally substituted alkyl group having 1 to 10 carbon atoms claim 1 , an optionally substituted alkenyl group having 2 to 10 carbon atoms claim 1 , an optionally substituted cycloalkyl group having 3 to 7 carbon atoms claim 1 , an optionally substituted aryl group having 6 to 10 carbon atoms claim 1 , an optionally substituted alkoxy group having 1 to 10 carbon atoms or an optionally substituted aryloxy group having 6 to 10 carbon atoms.5. An aromatic borylation catalyst comprising the bipyridyl compound according to as a ligand.6. The catalyst according to claim 5 , wherein the bipyridyl compound is coordinated to iridium. The present invention relates to a bipyridyl compound useful as a ligand of a metal catalyst and a catalyst including the same bipyridyl compound as a ligand.The Suzuki-Miyaura reaction performing a cross coupling between an organic halogen compound and an organic boron compound is an important method for carbon-carbon bond formation ...

ALKANE DEHYDROGENATION PROCESS

Disclosed herein are processes for dehydrogenation of an alkane to an alkene using an iridium pincer complex. In the dehydrogenation reactions, hydrogen that is co-formed during the process must be removed for the chemical reaction to proceed and to prevent the excess hydrogen from poisoning the catalyst. In one embodiment the process comprises providing an alkane feedstock comprising at least one alkane and contacting the alkane with an iridium pincer complex in the presence of a hydrogen acceptor selected from the group consisting of ethylene, propene, or mixtures to form an alkene product. The processes disclosed herein can accomplish facile, low-temperature transfer dehydrogenation of alkanes with unprecedented selectivities and TONs at a reasonable rate of conversion. 1. A process for preparing alpha-olefins from an at least one alkane , comprising the steps of:providing an alkane feedstock in a gaseous phase comprising the at least one alkane;contacting the at least one alkane in the gaseous phase with an iridium pincer complex in the presence of a gaseous hydrogen acceptor selected from the group consisting of ethylene, propene, and mixtures thereof; andrecovering an alpha-olefin product.2. The process of claim 1 , wherein the at least one alkane in the gaseous phase is selected from the group consisting of a butane claim 1 , a pentane claim 1 , an octane claim 1 , a nonane claim 1 , a decane claim 1 , a dodecane claim 1 , and mixtures thereof.5. The process of claim 1 , wherein the iridium pincer complex is (PCP)Ir(CH) or (p-OK-PCP)Ir(CH).6. The process of claim 1 , wherein the iridium pincer complex is unsupported.7. The process of claim 1 , wherein the iridium pincer complex is immobilized on a solid support.8. The process of claim 7 , wherein the solid support is selected from the group consisting of a silica claim 7 , a γ-alumina claim 7 , a basic alumina claim 7 , a florisil claim 7 , and a neutral alumina.9. The process of claim 8 , wherein the solid ...

DEHYDROGENATION CATALYST, AND CARBONYL COMPOUND AND HYDROGEN PRODUCTION METHOD USING SAID CATALYST

Objects of the present invention are to provide a novel dehydrogenation reaction catalyst, to provide a method that can produce a ketone, an aldehyde, and a carboxylic acid with high efficiency from an alcohol, and to provide a method for efficiently producing hydrogen from an alcohol, formic acid, or a formate, and they are accomplished by a catalyst containing an organometallic compound of Formula (1). 2. The method according to claim 1 , wherein the oxygen-containing compound is an alcohol.3. The method according to claim 1 , wherein the oxygen-containing compound is formic acid or a formate.4. The method according to claim 1 , wherein L is an aquo ligand.5. The method according to claim 1 , wherein Ar is an optionally substituted cyclopentadienyl group claim 1 , and M is iridium.6. A dehydrogenation catalyst comprising an organometallic compound of Formula (1) claim 1 , wherein it is for use in the method according to .7. A method for producing a carbonyl compound claim 1 , wherein an alcohol is dehydrogenated by use of the dehydrogenation method according to to produce a corresponding carbonyl compound.8. The method according to claim 7 , wherein the carbonyl compound is a ketone or an aldehyde.9. The method according to claim 7 , wherein the alcohol is a primary alcohol claim 7 , the carbonyl compound is a carboxylic acid claim 7 , and a solvent comprising water is used.10. A method for producing hydrogen claim 1 , wherein hydrogen is prepared by dehydrogenation of an alcohol claim 1 , a mixture containing an alcohol and water claim 1 , formic acid claim 1 , or a formate using the dehydrogenation method according to .12. The organometallic compound according to claim 11 , wherein Ar is an optionally substituted cyclopentadienyl group claim 11 , and M is iridium.14. The organometallic compound according to claim 13 , wherein Ar is an optionally substituted cyclopentadienyl group claim 13 , and M is iridium.15. A method for dehydrogenating an oxygen-containing ...

ENANTIOSELECTIVE HYDROGENATION OF 4-SUBSTITUTED 1,2-DIHYDROQUINOLINES IN PRESENCE OF A CHIRAL IRIDIUM CATALYST

The invention relates to a process for preparing optically active 4-substituted 1,2,3,4-tetrahydroquinolines comprising enantioselective hydrogenation of the corresponding 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium (P,N)-ligand catalyst. 2: The process according to claim 1 , wherein{'sup': '1', 'sub': 1', '6', '6', '14', '1', '4, 'claim-text': {'sub': 6', '14', '6', '14', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4, 'wherein C-C-aryl in the C-C-aryl-C-C-alkyl moiety is unsubstituted or substituted by one to five substituents selected from the group consisting of halogen, C-C-alkyl, C-C-haloalkyl, C-C-alkoxy and C-C-haloalkoxy'}, 'Ris C-C-alkyl or C-C-aryl-C-C-alkyl,'}{'sup': 2', '3, 'sub': 1', '4, 'Rand Rare the same and are selected from C-C-alkyl,'}{'sup': '4', 'sub': 1', '4', '1', '4', '1', '4', '1', '4, 'Ris C-C-alkyl, C-C-haloalkyl, C-C-alkoxy, C-C-haloalkoxy, phenyl or benzyl,'}n is 0, 1 or 2, and{'sup': '5', 'sub': 1', '6', '1', '6, 'each substituent R, if present, is independently selected from the group consisting of halogen, C-C-alkyl and C-C-haloalkyl.'}3: The process according to claim 1 , wherein{'sup': '1', 'Ris methyl, ethyl or n-propyl,'}{'sup': 2', '3, 'Rand Rare methyl,'}{'sup': '4', 'sub': 1', '4, 'Ris C-C-alkyl,'}n is 0, 1 or 2, and{'sup': '5', 'sub': 1', '6, 'each substituent R, if present, is independently selected from the group consisting of halogen and C-C-alkyl.'}6: The process according to claim 1 , wherein the hydrogenation is conducted using hydrogen gas at a pressure of from 1 to 300 bar.7: The process according to claim 1 , wherein the amount of iridium catalyst used is within the range of from 0.001 mol % to 5 mol % claim 1 , based on the amount of the compound of the formula (II).8: The process according to claim 1 , wherein the hydrogenation is conducted at a temperature within the range of from 20° C. to 130° C.9: The process according to claim 1 , wherein the hydrogenation is conducted in presence of a ...

Dehydrogenation of neat formic acid

A formic acid decomposition catalyst system includes metal-ligand complexes having formula 1: wherein M is a transition metal; R 1 , R 2 are independently C 1-6 alkyl groups; o is 1, 2, 3, or 4; R 3 are independently hydrogen, C 1-6 alkyl groups, OR 14 , NO 2 , or halogen; R 4 , R 5 , R 6 , R 7 , R 8 , R 9 , R 10 , R 11 , R 12 , R 13 , are independently hydrogen or C 1-6 alkyl groups; R 14 is a C 1-6 alkyl group; and X − is a negatively charge counter ion.

Methods for producing butanol

Methods and compositions for producing 1-butanol are described herein. In some examples, the methods can comprise, contacting a reactant comprising ethanol with a catalyst system, thereby producing a product comprising 1-butanol. The catalyst system can comprise, for example, an iridium catalyst and a nickel, copper, and/or zinc catalyst. The nickel, copper, and zinc catalysts can comprise nickel, copper, and/or zinc and a sterically bulky ligand.

HETEROGENEOUS CATALYSTS FOR NMR/MRI ENHANCEMENT VIA SIGNAL AMPLIFICATION BY REVERSIBLE EXCHANGE (SABRE)

Heterogeneous iridium catalysts for nuclear spin polarization enhancement in solution via signal amplification by reversible exchange are provided. Also provided are methods for preparing heterogeneous iridium catalysts, and methods of using heterogeneous iridium catalysts for nuclear spin polarization enhancement in solution via signal amplification by reversible exchange. 4. The catalyst of claim 1 , wherein the solid support is selected from a nanoparticle claim 1 , a titanium dioxide nanoparticle claim 1 , silica claim 1 , a polymer microbead claim 1 , and a polystyrene microbead.5. The catalyst of claim 1 , wherein L is a bond.6. The catalyst of claim 1 , wherein L is a linker claim 1 , wherein the linker is derived from an amino acid or 4-dimethylamino-pyridine.7. The catalyst of claim 1 , wherein Ris mesityl.8. The catalyst of claim 1 , wherein Ris mesityl.9. The catalyst of claim 1 , wherein Rand Rare each hydrogen.10. The catalyst of claim 1 , wherein Ris chloro.11. The catalyst of claim 1 , wherein Ris an unsubstituted or substituted pyridinyl.15. The catalyst of claim 14 , wherein the solid support is a TiOnanoparticle. This application claims priority to U.S. Provisional Application No. 62/025,743, filed Jul. 17, 2014, which is herein incorporated by reference in its entirety.This invention was made with government support under Award No. W81XWH-12-1-0159/BC112431 awarded by the Department of Defense; Grant No. 3R00CA134749-03 awarded by the National Institutes of Health; Grant No. 1R21EB018014-01A1 awarded by the National Institutes of Health; Grant No. CHE-1416268 awarded by the National Science Foundation; and Grant No. CHE-1416432 awarded by the National Science Foundation. The Government has certain rights in the invention.The present disclosure relates to heterogeneous catalysts, and more particularly, to preparation and use of heterogeneous iridium catalysts for nuclear spin polarization enhancement in solution via signal amplification by ...

Metallorganocatalysis For Asymmetric Transformations

A ligand having the structure or its enantiomer; (I) wherein: each one of R a , R b , R c and R d is selected from alkyl, cycloalkyl, and aryl; the bridge group is selected from CH 2 NH; *CH(CH 3 )NH(C*,R); and the organocatalyst is an organic molecule catalyst covalently bound to the bridge group. Also, a catalyst having the structure or its enantiomer: (II) wherein: each one of R a , R b , R c and R d is selected from alkyl, cycloalkyl, and aryl; the bridge group is selected from CH 2 NH; *CH(CH 3 )NH(C*,R); and *CH(CH 3 )NH(C*,S); the organocatalyst is an organic molecule catalyst covalently bound to the bridge group; and M is selected from the group consisting of Rh, Pd, Cu, Ru, Ir, Ag, Au, Zn, Ni, Co, and Fe.

Process for the Decarboxylation, Isomerization, Hydrogenation, Dehydrogenation and Cyclization Aromatization of Fatty Acids Yielding Products with Significant Aromatic Content

Disclosed herein are processes for the decarboxylation, isomerization, hydrogenation, dehydrogenation, and cyclization/aromatization of fatty acids involving contacting a starting material which is an unsaturated fatty acid, unsaturated fatty acid derivative, or an unsaturated triglyceride, in the presence of a catalyst at a temperature at which decarboxylation, isomerization, hydrogenation, dehydrogenation, and cyclization/aromatization occurs and recovering the unsaturated organic compound product; wherein the catalyst is chloro-1,5-cyclooctadiene iridium (I) dimer. The product may contain at least about 8% by volume aromatic content and less than about 25% by volume aromatic content, and wherein the product contains less than about 1% by volume of naphthalenes.

Method of Manufacturing Nitrone Compound

A method of manufacturing nitrone compounds is provided. The method includes: providing a nitro compound; and performing a photoreaction of the nitro compound, a catalyst and an additive under visible light to obtain the nitrone compound. 1. A method of manufacturing nitrone compound , comprising:providing a nitro compound; andperforming a photoreaction of the nitro compound, a catalyst and an additive under visible light to obtain the nitrone compound.2. The method of claim 1 , wherein the catalyst is Ru(bpy)Cl.6HO claim 1 , Ru(bpy)Cl claim 1 , Ru(bpy)(BF) claim 1 , Ru(bpy)(PF) claim 1 , Ir[dF(CF)ppy](dtbbpy)(PF) or Ir(ppy)(dtbbpy)(PF).3. The method of claim 1 , wherein a wavelength of the visible light is within the range of 350 to 700 nm.4. The method of claim 3 , wherein a wavelength of the visible light is within the range of 450 to 460 nm.5. The method of claim 1 , wherein the nitro compound is a second order or third order nitro compound.6. The method of claim 1 , wherein the additive is diisopropylethylamine (DIPEA) claim 1 , diisopropylisobutylamine (DIPIBA) or a derivative of 1 claim 1 ,4-Dihydropyridine (DHP).7. The method of claim 6 , wherein when the additive is diisopropylisobutylamine (DIPIBA) claim 6 , an aldehyde compound is further added in the photoreaction.8. The method of claim 6 , wherein the derivative of 1 claim 6 ,4-Dihydropyridine (DHP) is Hantzsch ester.9. The method of claim 1 , wherein the catalyst is performed a photoredox catalyst reaction in the photoreaction. This application claims priority from Taiwan Patent Application No. 104125714, filed on Aug. 6, 2015, in the Taiwan Intellectual Property Office, the content of which are hereby incorporated by reference in their entirety for all purposes.1. Field of the InventionThe present invention relates to a manufacturing method, in particular with respect to a manufacturing method of manufacturing nitrone compound.2. Description of the Related ArtNitrone compound is a key intermediate for ...

NEW DIPHOSPHITES BASED ON CIS-BUTENE-1,4-DIOL

New diphosphites based on cis-butene-1,4-diol. 2. Compound according to claim 1 ,{'sup': ['1', '4', '5', '8'], 'sub': ['1', '12'], '#text': 'where R, R, R, Rare selected from: —H, —(C-C) alkyl.'}3. Compound according to claim 1 ,{'sup': ['1', '4', '5', '8', 'l'], '#text': 'where the radicals R, R, R, Rare not all simultaneously —Bu.'}4. Compound according to claim 1 ,{'sup': ['1', '4', '5', '8', 'l'], '#text': 'where the radicals R, R, R, Rare not —Bu.'}5. Compound according to claim 1 ,{'sup': ['1', '4', '5', '8'], '#text': 'where at least one of the radicals R, R, R, Ris —H.'}6. Compound according to claim 1 ,{'sup': ['2', '3', '6', '7'], 'sub': ['1', '12'], '#text': 'where R, R, R, Rare selected from: —H, —O—(C-C) alkyl.'}7. Compound according to claim 1 ,{'sup': ['2', '3', '6', '7'], '#text': 'where at least one of the radicals R, R, R, Ris —H.'}8. Compound according to claim 1 ,where the compound has the structure (I).10. Compound according to claim 1 ,where the compound has the structure (II).12. Use of a compound according to in a ligand-metal complex for catalysis of a hydroformylation reaction.13. Process comprising the process steps of:a) initially charging an olefin,{'claim-ref': {'@idref': 'CLM-00001', '#text': 'claim 1'}, '#text': 'b) adding a compound according to and a substance containing a metal selected from: Rh, Ru, Co, Ir,'}{'sub': '2', '#text': 'c) feeding in Hand CO,'}d) heating the reaction mixture from steps a) to c), with conversion of the olefin to an aldehyde. The invention relates to new diphosphites based on cis-butene-1,4-diol.Phosphorus-containing compounds play a crucial role as ligands in a multitude of reactions, e.g. in hydrogenation, in hydrocyanation and also in hydroformylation.The reactions between olefin compounds, carbon monoxide and hydrogen in the presence of a catalyst to give the aldehydes with one carbon atom more are known as hydroformylation or the oxo process. Catalysts used in these reactions are frequently compounds ...

WATER SOLUBLE CATALYSTS FOR NMR/MRI ENHANCEMENT

Iridium catalysts for nuclear spin polarization enhancement in solution via signal amplification by reversible exchange are provided. The iridium catalysts can be water-soluble iridium catalysts. Also provided are methods for preparing iridium catalysts, and methods of activating and using iridium catalysts for nuclear spin polarization enhancement in solution via signal amplification by reversible exchange. 2. The compound of claim 1 , wherein the water-solubilizing substituent group is a polyethylene glycol-containing substituent group claim 1 , a hydroxyl group claim 1 , an alkoxy group claim 1 , a carboxylic acid group claim 1 , or a combination thereof.3. The compound of claim 1 , wherein Ris mesityl.4. The compound of claim 1 , wherein Rand Rare hydrogen.5. The compound of claim 1 , wherein Ris chloro.7. The compound of claim 1 , wherein m is 0.8. The compound of claim 1 , wherein m is 2 and each Ris hydroxy.12. The compound of claim 11 , wherein n averages 12.16. The method of claim 15 , wherein the solvent is an alcoholic solvent.17. The method of claim 16 , wherein the alcoholic solvent is ethanol.18. The method of claim 15 , wherein the substrate is nicotinamide.19. The method of claim 15 , wherein the substrate is pyridine.20. The method of claim 15 , further comprising:removing the solvent to provide a solid activated catalyst; andreconstituting the activated catalyst in an aqueous solvent.21. The method of claim 20 , wherein the aqueous solvent comprises water and ethanol.23. The method of claim 22 , wherein the substrate is nicotinamide.24. The method of claim 22 , wherein the substrate is pyridine.25. The method of claim 22 , wherein the substrate is a lutidine.26. The method of claim 22 , wherein the substrate is a picoline.27. The method of claim 22 , wherein the catalyst of formula (II) is IrCl(COD)(IMes) where IMes is 1 claim 22 ,3-bis(2 claim 22 ,4 claim 22 ,6-trimethylphenyl)imidazole-2-ylidene and COD is cyclooctadiene.29. The method of claim ...

Methods of Activating Metal Complexes for Catalysts

The present invention is directed to the activation of metal carbonyl clusters by an oxidative agent to prepare a stable metal cluster catalyst exhibiting catalytic rate enhancement. The activation comprises, for example, using oxygen for decarbonylation of carbonyl ligands and changing the oxidation state of the other ligands. In one aspect, treatment of the metal cluster catalyst under oxidative conditions in a flow reactor leads to removal of CO ligands and oxidation of bound calixarene phosphine ligands, and results in a stable activated open metal cluster that is more active for ethylene hydrogenation catalysis. The resulting metal cluster contains coordinatively unsaturated sites comprising carbonyl vacancies. In one aspect, the resulting activated open metal cluster can be used as a catalyst in a variety of chemical transformations.

Alkane-Alkene Coupling Via Tandem Alkane-Dehydrogenation/Alkene-Dimerization Catalyzed by Pincer Iridium Catalyst Heterogenized on Solid Supports

Disclosed herein are processes for tandem alkene dehydrogenation/alkene dimerization using an iridium pincer complex catalyst on a support comprising magnesium silicates (e.g., Florisil®). The reaction process comprises providing an iridium pincer complex bound to a solid support comprising magnesium silicates; providing a gaseous alkane feedstock comprising at least one alkane; and contacting the gaseous alkane feedstock with the iridium pincer complex bound to the solid support in the presence of a hydrogen acceptor to form dimerized alkenes. The processes disclosed herein can accomplish facile, low-temperature tandem transfer dehydrogenation of alkanes and dimerization of alkenes with unprecedented TONs at a reasonable rate of conversion. 1. A process for preparing dimerized alkenes in a tandem dehydrogenation/alkene dimerization reaction comprising:providing an iridium pincer complex bound to a solid support comprising magnesium silicates;providing a gaseous alkane feedstock comprising at least one alkane;contacting the gaseous alkane feedstock with the iridium pincer complex bound to the solid support in the presence of a hydrogen acceptor to form the dimerized alkenes; andrecovering the dimerized alkenes as recovered dimerized alkenes.2. The process of claim 1 , wherein the at least one alkane of the gaseous alkane feedstock comprises 4 or 5 carbons.3. The process of claim 1 , wherein the recovered dimerized alkenes comprise Cdimerized alkenes.4. The process of claim 3 , wherein the recovered dimerized alkenes comprise Cdimerized alkenes.5. The process of claim 1 , wherein the hydrogen acceptor comprises ethylene claim 1 , propene or mixtures thereof.6. The process of claim 1 , wherein the iridium pincer complex is (p-OM-PCP)Ir(CH) bound to the solid support comprising magnesium silicate claim 1 , where M is K or the solid support.7. The process of claim 1 , wherein the process has a TON for Cproducts of at least 100 at 10 minutes.8. The process of claim 1 , ...

METHOD FOR PRODUCING NOVEL ORGANOMETALLIC COMPLEX AND AMINE COMPOUND

The purpose of the invention is to provide a novel organometallic compound that can be utilized as a catalyst having high generality, high activity, and excellent functional group selectivity. The invention pertains to a novel organometallic compound represented by general formula (1) that catalyzes a reductive amination reaction. 2. The organometallic compound according to claim 1 , wherein the electron-withdrawing group is —S(═O)—R claim 1 , a 6- to 20-membered aryl group in which a carbon atom may be replaced by a heteroatom claim 1 , —C(═O)—OR claim 1 , —C(═O)—R claim 1 , —C(═O)—NRR claim 1 , —C(═S)—NRR claim 1 , a C1-C20 sulfenyl group or a perfluoroalkyl group claim 1 , in which one or more hydrogen atoms of these groups may be substituted by a substituent W.3. The organometallic compound according to claim 1 , wherein the electron-withdrawing group is —S(═O)—R claim 1 , —C(═O)—R claim 1 , or —C(═O)—NRR claim 1 , in which one or more hydrogen atoms of these groups may be substituted by a substituent W.4. The organometallic compound according to claim 1 , characterized in that Ar is a cyclopentadienyl group in which one or more hydrogen atoms may be substituted by a substituent W claim 1 , and M is iridium or rhodium.5. The organometallic compound according to claim 1 , characterized in that n=0.6. The organometallic compound according to claim 1 , wherein A is a saturated or unsaturated 4- to 6-membered heterocycle having only one nitrogen atom as the ring member heteroatom.7. The organometallic compound according to claim 1 , wherein A is a saturated or unsaturated 4- to 6-membered heterocycle comprising one or more heteroatoms selected from the group consisting of nitrogen atom claim 1 , oxygen atom and sulfur atom claim 1 , in addition to one nitrogen atom.8. The organometallic compound according to claim 1 , wherein A is an aromatic ring.9. The organometallic compound according to claim 1 , wherein an organometallic complex of general formula (1) is an ...

METHOD AND APPARATUS FOR CARBONYLATING METHANOL WITH ACETIC ACID ENRICHED FLASH STREAM

A carbonylation process for producing acetic acid including: (a) carbonylating methanol or its reactive derivatives in the presence of a Group VIII metal catalyst and methyl iodide promoter to produce a liquid reaction mixture including acetic acid, water, methyl acetate and methyl iodide; (b) feeding the liquid reaction mixture at a feed temperature to a flash vessel which is maintained at a reduced pressure; (c) heating the flash vessel while concurrently flashing the reaction mixture to produce a crude product vapor stream, wherein the reaction mixture is selected and the flow rate of the reaction mixture fed to the flash vessel as well as the amount of heat supplied to the flash vessel is controlled such that the temperature of the crude product vapor stream is maintained at a temperature less than 90° F. cooler than the feed temperature of the liquid reaction mixture to the flasher and the concentration of acetic acid in the crude product vapor stream is greater than 70% by weight of the crude product vapor stream. 125.-. (canceled)26. A carbonylation process for producing acetic acid comprising:(a) carbonylating methanol or its reactive derivatives in a reactor in the presence of a rhodium metal catalyst and methyl iodide promoter to produce a liquid reaction mixture including acetic acid, water, methyl acetate and methyl iodide;(b) feeding the liquid reaction mixture to a flash vessel and heating the liquid reaction mixture in the flash vessel to separate the liquid reaction mixture into a crude product vapor stream and a catalyst solution;(c) recycling the catalyst solution to the reactor;(d) separating the crude product vapor stream in a first distillation column into an overhead stream comprising methyl iodide, methyl acetate and water and process stream comprising acetic acid; and(e) condensing the overhead stream and separating the condensed overhead stream into an aqueous stream and an organic stream,wherein the ratio of the crude product vapor stream ...

METHOD AND APPARATUS FOR CARBONYLATING METHANOL WITH ACETIC ACID ENRICHED FLASH STREAM

A carbonylation process for producing acetic acid including: (a) carbonylating methanol or its reactive derivatives in the presence of a Group VIII metal catalyst and methyl iodide promoter to produce a liquid reaction mixture including acetic acid, water, methyl acetate and methyl iodide; (b) feeding the liquid reaction mixture at a feed temperature to a flash vessel which is maintained at a reduced pressure; (c) heating the flash vessel while concurrently flashing the reaction mixture to produce a crude product vapor stream, wherein the reaction mixture is selected and the flow rate of the reaction mixture fed to the flash vessel as well as the amount of heat supplied to the flash vessel is controlled such that the temperature of the crude product vapor stream is maintained at a temperature less than 90° F. cooler than the feed temperature of the liquid reaction mixture to the flasher and the concentration of acetic acid in the crude product vapor stream is greater than 70% by weight of the crude product vapor stream. 125-. (canceled)26. A carbonylation process for producing acetic acid comprising:carbonylating methanol or its reactive derivatives in the presence of a rhodium catalyst in a reactor to produce a liquid reaction mixture comprising acetic acid, the rhodium metal catalyst, water, iodide catalyst stabilizer, methyl acetate and methyl iodide;flashing the liquid reaction mixture in a flash vessel to form a crude product vapor stream comprising acetic acid, methyl iodide, and methyl acetate, and a catalyst solution comprising the rhodium metal catalyst, iodide catalyst stabilizer, methyl acetate, and water; and distilling the crude product vapor stream to form a first overhead, and a side stream comprising acetic acid; and', 'distilling the side stream into a second overhead, and a purified acetic acid stream,, 'an acetic acid collection step comprisingwherein the catalyst solution comprises methyl acetate in an amount less than or equal to 1.9% by weight ...

Catalyst compounds

The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formula: (Formula (I)) where ring B is a conjugated ring system with one or more substituents. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.

Novel Catalyst Complex and Use Thereof in Alkane Oligomerization

Provided is a Group 9 novel metal catalyst complex further comprising a ketone-containing cocatalyst. The metal catalyst complex is useful in generating olefins from alkanes with great efficiency. In one embodiment, provided is an iridium catalyst complex useful in the dehydrogenation of alkanes comprising a ketone-containing cocatalyst and iridium complexed with a tridentate ligand. Also provided is a novel dehydrogenation method which utilizes the catalyst composition. In other embodiments, a novel process for preparing oligomers from alkanes utilizing the catalyst composition is provided. 1. A catalyst composition useful in the dehydrogenation of alkanes comprising a ketone containing cocatalyst and a Group 9 metal complex.2. The catalyst composition of claim 1 , wherein the Group 9 metal is iridium.3. The catalyst composition of claim 1 , wherein the ketone containing cocatalyst comprises benzophenone.4. The catalyst composition of claim 1 , wherein the Group 9 metal is associated with tridentate ligands.5. The catalyst of claim 1 , wherein the metal complex is a composition of the formula LMX(X′) claim 1 , where n=0 claim 1 , 1 or 2;X and X′ are moieties into which a monomer can insert or which can be eliminated from the metal center to generate a fragment LM;M is a Group 9 metal; andL is a tridentate ligand.6. The catalyst complex of claim 5 , wherein X and X′ are independently selected from the group consisting of halides claim 5 , hydride claim 5 , triflate claim 5 , acetates claim 5 , borates claim 5 , Cthrough Calky claim 5 , Cthrough Calkoxy claim 5 , Cthrough Ccycloalkyl claim 5 , Cthrough Ccycloalkoxy claim 5 , aryl and olefins.8. The catalyst complex of claim 5 , wherein the ligand is 2 claim 5 ,6-bis (di-iso-propylphosphino) phenyl-1.9. A method of dehydrogenating alkanes which comprises contacting an alkane under dehydrogenation conditions in the presence of the catalyst of .10. A method of dehydrogenating alkanes which comprises contacting an alkane ...

BIPYRIDYL COMPOUND

There are provided a compound capable of being a novel ligand allowing regioselective borylation to be performed in the aromatic borylation reaction, and a catalyst using the same compound. There is provided a bipyridyl compound represented by a general formula (1): (wherein A represents a single bond, a vinylene group or an ethynylene group; 2. The bipyridyl compound according to claim 1 , wherein A is a single bond.3. The bipyridyl compound according to claim 1 , wherein Ris a hydrogen atom claim 1 , a halogen atom claim 1 , an alkyl group having 1 to 10 carbon atoms claim 1 , an alkenyl group having 2 to 10 carbon atoms claim 1 , a cycloalkyl group having 3 to 7 carbon atoms claim 1 , an aryl group having 6 to 10 carbon atoms claim 1 , an aryloxy group having 6 to 10 carbon atoms claim 1 , an alkoxy group having 1 to 10 carbon atoms claim 1 , a C-alkylamino group claim 1 , a di (Calkyl) amino group or a C-alkoxycarbonyl group.4. The bipyridyl compound according to claim 1 , wherein Ris a hydrogen atom claim 1 , an optionally substituted alkyl group having 1 to 10 carbon atoms claim 1 , an optionally substituted alkenyl group having 2 to 10 carbon atoms claim 1 , an optionally substituted cycloalkyl group having 3 to 7 carbon atoms claim 1 , an optionally substituted aryl group having 6 to 10 carbon atoms claim 1 , an optionally substituted alkoxy group having 1 to 10 carbon atoms or an optionally substituted aryloxy group having 6 to 10 carbon atoms.5. The bipyridyl compound according to claim 1 , wherein when Ris a substituted non-heterocyclic group claim 1 , the substitution is selected from the group consisting of 1 to 3 halogen atoms claim 1 , a cyano group claim 1 , a halogeno Calkyl group and a Calkoxy group.6. The bipyridyl compound according to claim 1 , which is 1-(2-([2 claim 1 ,2′-Bipyridin]-5-yl)phenyl)-3-(4-methoxyphenyl)urea.7. The bipyridyl compound according to claim 1 , which is 1-(2-([2 claim 1 ,2′-Bipyridin]-5-yl)phenyl)-3-cyclohexylthiourea.8. ...

DIPHOSPHITES HAVING AN OPEN, 2,4-METHYLATED OUTER UNIT

Diphosphites having an open, 2,4-methylated outer unit and use thereof in hydroformylation. 2. Compound according to claim 1 ,{'sup': 1', '3, 'sub': 1', '12, 'where R, Rare selected from: —H, —(C-C)-alkyl.'}3. Compound according to claim 1 ,{'sup': 1', '3, 'sub': 1', '12, 'where R, Rare —(C-C)-alkyl.'}4. Compound according to claim 1 ,{'sup': 1', '3, 'where R, Rare the same radical.'}5. Compound according to claim 1 ,{'sup': 2', '4, 'sub': 1', '12, 'where R, Rare selected from: —H, —O—(C-C) alkyl.'}6. Compound according to claim 1 ,{'sup': 2', '4, 'sub': 1', '12, 'wherein R, Rare —O—(C-C)-alkyl.'}7. Compound according to claim 1 ,{'sup': 2', '4, 'where R, Rare the same radical.'}8. Compound according to claim 1 ,{'sup': 1', '2', '3', '4, 'sub': '3', 'where R, R, R, Rare not all simultaneously —CH.'}10. Use of a compound according to in a ligand-metal complex for catalysis of a hydroformylation reaction.11. Process comprising the process steps of:a) initially charging an olefin,{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'b) adding a compound according to and a substance containing a metal selected from: Rh, Ru, Co, Ir,'}{'sub': '2', 'c) supplying Hand CO,'}d) heating the reaction mixture from steps a) to c), with conversion of the olefin to an aldehyde. The invention relates to diphosphites having an open, 2,4-methylated outer unit and use thereof in hydroformylation.Phosphorus-containing compounds play a crucial role as ligands in a multitude of reactions, e.g. in hydrogenation, in hydrocyanation and also in hydroformylation.The reactions between olefin compounds, carbon monoxide and hydrogen in the presence of a catalyst to give the aldehydes with one carbon atom more are known as hydroformylation or the oxo process. In these reactions, compounds of the transition metals of group VIII of the Periodic Table of the Elements are frequently employed as catalysts. Known ligands are, for example, compounds from the phosphine, phosphite and phosphorite classes, ...

CATALYST COMPOUNDS

The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions. 2. (canceled)3. The catalyst compound of claim 1 , wherein ring A of the Formula I or ring A of the Formula A is phenyl claim 1 , optionally substituted claim 1 , in either or both of the ortho- or para-position relative to the imine nitrogen atom to which ring A is attached claim 1 , by one or two groups each independently selected from the group consisting of hydroxyl claim 1 , NRR claim 1 , (1-3C)alkyl claim 1 , (1-3C)alkoxy and aryl which is optionally substituted by halogeno claim 1 , hydroxyl claim 1 , NRR claim 1 , (1-3C)alkyl or (1-3C)alkoxy claim 1 , wherein Rand Rare each independently hydrogen or (1-2C)alkyl.4. The catalyst compound of claim 1 , wherein ring A of the Formula I or ring A of the Formula A is para-methoxyphenyl.5. The catalyst compound of claim 1 , wherein ring B of the Formula I is naphthyl claim 1 , optionally substituted by one or more groups selected from the group consisting of halogeno claim 1 , hydroxyl claim 1 , NRR claim 1 , (1-6C)alkyl claim 1 , (1-6C)alkoxy claim 1 , [NRRR] claim 1 , nitro claim 1 , cyano claim 1 , formyl claim 1 , carboxy claim 1 , carbamoyl claim 1 , sulphamoyl claim 1 , ureido claim 1 , isocyano claim 1 , sulphonyl claim 1 , sulphonate claim 1 , trihalomethyl claim 1 , and mercapto claim 1 , wherein R claim 1 , R claim 1 , and Rare each independently hydrogen claim 1 , (1-6C)alkyl or aryl claim 1 , or a group of the formula:{'br': None, 'sub': 1', '1, 'L-Q'}wherein:{'sub': 1', '2', '2', '2, 'sup': f', 'f', 'f', 'f', 'f', 'g', 'f', 'f', 'f', 'g, 'Lis ...

PROCESS FOR PRODUCING HETEROCYCLIC COMPOUND

The present invention provides a method of efficiently producing an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative. The optically active piperidine-3-carboxamide or a derivative thereof, which is obtained by subjecting 1,4,5,6-tetrahydropyridine-3-carboxamide or a derivative thereof to an asymmetric reduction in the presence of a catalyst, is used as an intermediate. 2. The method according to claim 1 , wherein the organic metal complex is a transition metal complex.3. The method according to claim 2 , wherein the transition metal complex is a ruthenium complex.4. The method according to claim 3 , wherein the ruthenium complex is represented by the formula:{'br': None, 'sup': 'a', 'sub': '2', '[Ru(OCOR)L*]\u2003\u2003(VIII)'}wherein{'sup': 'a', 'sub': '1-3', 'Ris an optionally substituted Calkyl group; and'}{'sup': 'a', 'Lis a diphosphine ligand.'} This application is a divisional of U.S. application Ser. No. 15/125,299, which is the U.S. National Stage application of PCT/JP2015/057541, filed Mar. 13, 2015, which claims priority from Japanese application 2014-052809, filed Mar. 14, 2014.The present invention relates to a production method of an optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative which is useful as a dipeptidylpeptidase inhibitor, and various intermediates useful therefor, and production methods thereof.An optically active 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative is known to be useful as a dipeptidylpeptidase inhibitor and an agent for the treatment of diabetes.Patent Document 1 discloses a method of producing a 6-(3-aminopiperidin-1-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative by reacting optically active 3-aminopiperidine with a 6-chloro-2,4-dioxo-1,2,3,4-tetrahydropyrimidine derivative.Patent Document 2 discloses a method of efficiently producing an optically active 8-(3-aminopiperidin-1-yl)xanthine derivative by ...

DEHYDROGENATION CATALYST, AND CARBONYL COMPOUND AND HYDROGEN PRODUCTION METHOD USING SAID CATALYST

Objects of the present invention are to provide a novel dehydrogenation reaction catalyst, to provide a method that can produce a ketone, an aldehyde, and a carboxylic acid with high efficiency from an alcohol, and to provide a method for efficiently producing hydrogen from an alcohol, formic acid, or a formate, and they are accomplished by a catalyst containing an organometallic compound of Formula (1). 2. The method according to claim 1 , wherein the oxygen-containing compound is an alcohol.3. The method according to claim 1 , wherein the oxygen-containing compound is formic acid or a formate.4. The method according to claim 1 , wherein L is an aquo ligand.5. The method according to claim 1 , wherein Ar is an optionally substituted cyclopentadienyl group claim 1 , and M is iridium.6. A dehydrogenation catalyst comprising an organometallic compound of Formula (1) claim 1 , wherein it is for use in the method according to .7. A method for producing a carbonyl compound claim 1 , wherein an alcohol is dehydrogenated by use of the dehydrogenation method according to to produce a corresponding carbonyl compound.8. The method according to claim 7 , wherein the carbonyl compound is a ketone or an aldehyde.9. The method according to claim 7 , wherein the alcohol is a primary alcohol claim 7 , the carbonyl compound is a carboxylic acid claim 7 , and a solvent comprising water is used.10. A method for producing hydrogen claim 1 , wherein hydrogen is prepared by dehydrogenation of an alcohol claim 1 , a mixture containing an alcohol and water claim 1 , formic acid claim 1 , or a formate using the dehydrogenation method according to .12. The organometallic compound according to claim 11 , wherein Ar is an optionally substituted cyclopentadienyl group claim 11 , and M is iridium.14. The organometallic compound according to claim 13 , wherein Ar is an optionally substituted cyclopentadienyl group claim 13 , and M is iridium.15. A method for dehydrogenating an oxygen-containing ...

CATALYST AND BATTERY COMPONENTS DERIVED FROM CONDENSATION REACTIONS WITH CARBA-CLOSO-DODECABORATE AMINES

Described herein is the fusion of two families of unique carbon-containing molecules that readily disregard the tendency of carbon to form four chemical bonds, namely N-heterocyclic carbenes (NHCs) and carborane anions. Deprotonation of an anionic imidazolium salt with lithium diisopropylamide at room temperature leads to a mixture of lithium complexes of C-2 and C-5 dianionic NHC constitutional isomers as well as a trianionic (C-2, C-5) adduct. Judicious choice of the base and reaction conditions allows for the selective formation of all three stable polyanionic carbenes. In solution, the so-called abnormal C-5 NHC lithium complex slowly isomerizes to the normal C-2 NHC, and the process can be proton catalyzed by the addition of the anionic imidazolium salt. These results indicate that the combination of two unusual forms of carbon atoms can lead to unexpected chemical behavior, and that this strategy paves the way for the development of a broad new generation of NHC ligands for catalysis. 2. The carborane compound according to claim 1 , wherein alkyl claim 1 , aryl claim 1 , silyl claim 1 , siloxy claim 1 , alkoxy claim 1 , and aryloxy in Rare optionally substituted with a member independently selected from the group consisting of hydrogen claim 1 , halogen claim 1 , hydroxyl claim 1 , and hydroxide.3. The carborane compound according to claim 1 , wherein Ris selected from alkyl and aryl.5. The carborane compound according to claim 1 , wherein Hetis selected from the group consisting of an N-heterocyclic carbene (NHC) moiety or an NHC precursor moiety.8. The carborane compound according to claim 7 , wherein{'sup': '1', 'each Ris independently selected from H, halogen, alkyl, aryl, silyl, siloxy, alkoxy, and aryloxy, and wherein'}{'sup': '1', 'each alkyl, aryl, silyl, siloxy, alkoxy, and aryloxy in Ris optionally substituted with a member independently selected from the group consisting of halogen, hydroxyl, and hydroxide.'}9. The carborane compound according to ...

Catalytic conversion of carbon dioxide to methanol

The present disclosure relates to a new catalytic process for the production of methanol from carbon dioxide, comprising: (1) the conversion of carbon dioxide and hydrogen to formic acid or formate salts; (2) converting the formic acid or formate salts to diformate esters of diols; (3) hydrogenating the diformate esters to methanol and diols. The diols produced from the hydrogenation reaction can be recovered and re-used to prepare the diformate esters.

Spiroketal-Based C2-Symmetric Scaffold For Asymmetric Catalysis

Provided herein is a compound of formula (I): 4. The compound of claim 1 , wherein at least one X is OH.5. (canceled)6. The compound of claim 1 , wherein at least one X is PAr.7. (canceled)8. The compound of claim 1 , wherein at least one X is OPAr.9. (canceled)10. The compound of claim 1 , wherein at least one X is P(O)Ar.1112.-. (canceled)13. The compound of claim 6 , wherein Ar comprises phenyl.14. The compound of claim 1 , wherein both X together form OPNR′.1518.-. (canceled)19. The compound of claim 14 , wherein R′ is methyl.2022.-. (canceled)23. The compound of claim 1 , wherein R is ethyl.2428.-. (canceled)29. The compound of claim 1 , wherein at least one R is 3-10 membered heterocycloalkyl having 1-4 heteroatoms independently selected from N claim 1 , O claim 1 , and S.3034.-. (canceled)36. A catalyst comprising the compound of formula (I) according to and a transition metal.37. The catalyst of claim 36 , wherein the transition metal comprises iridium claim 36 , palladium claim 36 , rhodium claim 36 , platinum claim 36 , copper claim 36 , nickel claim 36 , cobalt claim 36 , or gold.38. A method of preparing the catalyst of comprising admixing the compound of formula (I) and the transition metal to form the catalyst.39. (canceled)40. The method of claim 38 , wherein the transition metal comprises [Ir(COD)Cl] claim 38 , [Pd(allyl)Cl] claim 38 , or Pd(dba).41. The method of claim 38 , wherein the compound of formula (I) and the transition metal are provided in a molar ratio of about 6:1 to 1:1.42. A method comprising:{'claim-ref': {'@idref': 'CLM-00036', 'claim 36'}, 'admixing a first reactant, a second reactant, and the catalyst of under conditions sufficient to allow reaction of the first reactant and the second reactant to form a reaction product, wherein the reaction product comprises a chiral center and the reaction produces an enantiomeric excess (ee) of the reaction product.'}43. The method of claim 42 , wherein the reaction comprises a hydroarylation ...

NOVEL DIAMINE COMPOUND AND METAL COMPLEXES, AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS

The present invention relates to a novel diamine compound represented by the general formula (1), a ruthenium-diamine complex, an iridium-diamine complex, and a rhodium-diamine complex having the diamine compound as a ligand. Furthermore, the present invention relates to methods for selectively producing optically active compounds by using any of these complexes as a catalyst. 3. A method for producing an optically active amine or an optically active compound , comprising:{'claim-ref': {'@idref': 'CLM-00002', 'claim 2'}, 'reducing an imino group of an imine compound or an unsaturated bond of a heterocyclic compound in the presence of the complex according to and a hydrogen donor.'}4. The production method according to claim 3 , wherein the hydrogen donor is hydrogen.5. The production method according to claim 3 , wherein the hydrogen donor is selected from formic acid claim 3 , alkali metal formates claim 3 , and alcohols having a hydrogen atom on a carbon atom at an α-position of a carbon atom substituted with a hydroxyl group.6. A catalyst for asymmetric reduction claim 2 , comprising the complex according to .7. A method for asymmetric reduction of an imine compound or a heterocyclic compound comprising: reducing an imino group of the imine compound or an unsaturated bond of the heterocyclic compound in the presence of a catalyst comprising the complex according to and a hydrogen doner. The present invention relates to a novel diamine compound, a ruthenium-diamine complex, an iridium-diamine complex, and a rhodium-diamine complex having the diamine compound as a ligand, and methods for selectively producing optically active compounds important as precursors for synthesis of pharmaceuticals and functional materials by using any of these complexes as a catalyst.In the field of production of optically active amines, many asymmetric reactions including asymmetric reduction have been developed, and many asymmetric reactions using asymmetric metal complexes having ...

Low system memory detection

Methods, systems, and computer readable media may be operable to facilitate an anticipation of an execution of a process termination tool. An allocation stall counter may be queried at a certain frequency, and from the query of the allocation stall counter, a number of allocation stall counter increments occurring over a certain duration of time may be determined. If the number of allocation stall counter increments is greater than a threshold, a determination may be made that system memory is running low and that an execution of a process termination tool is imminent. In response to the determination that system memory is running low, a flag indicating that system memory is running low may be set, and one or more programs, in response to reading the flag, may free memory that is not necessary or required for execution.

Supported Metal Catalysts

The present invention relates to supported metal catalysts, wherein the catalysts are modified by at least one amine, a method for the preparation thereof and hydrogenation processes utilising the supported metal catalysts. 2. The supported metal catalyst of claim 1 , wherein the support is carbon claim 1 , alumina claim 1 , calcium carbonate claim 1 , titania claim 1 , silica claim 1 , zirconia claim 1 , ceria claim 1 , or a combination thereof.3. The supported metal catalyst of claim 2 , wherein the alumina is alpha-AlO claim 2 , beta-AlO claim 2 , gamma-AlO claim 2 , delta-AlO claim 2 , theta-AlOor a combination thereof.4. The supported metal catalyst of claim 2 , wherein the carbon is activated carbon claim 2 , carbon black claim 2 , graphite claim 2 , or a combination thereof.5. (canceled)6. (canceled)7. The supported metal catalyst of claim 1 , wherein the metal is ruthenium claim 1 , rhodium claim 1 , palladium claim 1 , osmium claim 1 , iridium claim 1 , platinum claim 1 , gold claim 1 , silver claim 1 , copper claim 1 , iron claim 1 , cobalt claim 1 , nickel claim 1 , or a combination thereof.8. The supported metal catalyst of claim 1 , wherein the metal is palladium claim 1 , platinum claim 1 , gold claim 1 , or a combination thereof.9. The supported metal catalyst of claim 1 , wherein the Group VIII or IB metal is present in a range of from 0.01 wt % to 20 wt % claim 1 , relative to the total weight of the supported metal catalyst.10. The supported metal catalyst of claim 1 , wherein the amine is a natural amino acid claim 1 , non-natural amino acid claim 1 , peptide claim 1 , alkylamine claim 1 , alkyldiamine claim 1 , alkylpolyamine claim 1 , or combinations thereof.11. The supported metal catalyst of claim 10 , wherein the amine is lysine claim 10 , glycine claim 10 , proline claim 10 , alanine claim 10 , serine claim 10 , phenylalanine claim 10 , asparagine claim 10 , aspartic acid claim 10 , valine claim 10 , butylamine claim 10 , 6-aminocaproic acid ...

LIGAND, METAL COMPLEX CONTAINING LIGAND, AND REACTION USING METAL COMPLEX CONTAINING LIGAND

A hydrogen transfer reaction may be more efficiently promoted by using a metal complex represented by Formula (2): 37-. (canceled)911-. (canceled)13. A method for producing a hydrogen transfer reaction product , comprising the step of:{'claim-ref': {'@idref': 'CLM-00008', 'claim 8'}, 'subjecting an organic compound to a dehydrogenation reaction (oxidation reaction) in the presence of the compound according to .'}14. (canceled)16. A method for producing a hydrogen transfer reaction product , comprising the step of:{'claim-ref': {'@idref': 'CLM-00015', 'claim 15'}, 'subjecting an organic compound to a hydrogenation reaction in the presence of the catalyst for hydrogenation reaction according to .'}19. The compound according to claim 18 , wherein claim 18 , in Formula (2a) claim 18 , Rare the same or different claim 18 , and each represents a methyl group claim 18 , ethyl group claim 18 , n-propyl group claim 18 , isopropyl group claim 18 , n-butyl group claim 18 , isobutyl group claim 18 , sec-butyl group claim 18 , pentyl group claim 18 , hexyl group claim 18 , or Ccycloalkyl group.21. A method for producing a dehydrogenation reaction product claim 18 , comprising the step of:{'claim-ref': {'@idref': 'CLM-00020', 'claim 20'}, 'subjecting an organic compound to a dehydrogenation reaction in the presence of the catalyst for dehydrogenation reaction according to .'}23. The compound according to claim 22 , wherein claim 22 , in Formula (2a) claim 22 , Rare the same or different claim 22 , and each represents a linear or branched Calkyl group claim 22 , or Ccycloalkyl group.25. A method for producing a dehydrogenation reaction product claim 22 , comprising the step of:{'claim-ref': {'@idref': 'CLM-00024', 'claim 24'}, 'subjecting an organic compound to a dehydrogenation reaction in the presence of the catalyst for dehydrogenation reaction according to .'} The present invention relates to a ligand, a metal complex comprising the ligand, and a reaction (specifically, ...

CATALYST COMPOSITION FOR HYDROFORMYLATION AND HYDROFORMYLATION METHOD USING THE SAME

The present invention relates to a catalyst composition for hydroformylation and a hydroformylation method using the same, and more particularly to a catalyst composition for hydroformylation including a phosphoramidite ligand and a transition metal catalyst, and a hydroformylation method using the catalyst composition. In accordance with the present invention, provided are a catalyst composition for hydroformylation which increases productivity and provides superior catalytic activity and stability while lowering an n/i ratio in generated aldehyde upon hydroformylation of an olefinic compound, and a method of hydroformylating an olefinic compound using the catalyst composition. [Representative Figure ] FIG. 3. The catalyst composition according to claim 1 , wherein the phosphoramidite ligand is comprised in an amount of 0.1 to 10% by weight based on a weight of the catalyst composition.4. The catalyst composition according to claim 1 , wherein a molar fraction of the phosphoramidite ligand is 1 to 500 based on 1 mole of a transition metal of the transition metal catalyst.5. The catalyst composition according to claim 1 , wherein the transition metal catalyst is a transition metal catalyst represented by Formula 3 below:{'br': None, 'sup': 1', '2', '3, 'sub': x', 'y', 'z, 'M(L)(L)(L)\u2003\u2003[Formula 3]'}wherein M is one selected from the group consisting of cobalt (Co), rhodium (Rh), iridium (Ir), ruthenium (Ru), iron (Fe), nickel (Ni), palladium (Pd), platinum (Pt), and osmium (Os),{'sup': 1', '2', '3, 'each of L, Land Lis independently one selected from the group consisting of hydrogen, carbonyl (CO), cyclooctadiene, norbornene, chlorine, triphenylphosphine (TPP) and acetylacetonato (AcAc), and'}x, y and z are each independently 0 to 5, but x, y and z are not simultaneouosly 0.6. The catalyst composition according to claim 1 , wherein the transition metal catalyst is one or more selected from the group consisting of cobaltcarbonyl [Co(CO)] claim 1 , ...

HYDROGENATION AND DISPROPORTIONATION CATALYSIS

Improved catalytic methods are disclosed. The methods include both hydrogenation and disproportionation catalysis. While the reaction conditions for hydrogenation and disproportionation differ, the catalysts disclosed herein can be used for either process. In certain aspects, the methods utilize a catalyst: CpM(N—N)L; wherein Cp is a substituted or unsubstituted cyclopentadienyl ligand; wherein M is selected from the group consisting of Ir and Rh; wherein N—N is a substituted or unsubstituted bidentate ligand selected from the group consisting of a bipyridine ligand and a phenanthroline ligand; wherein n is 0 or 1; and wherein when n is 1 L is selected from the group consisting of an anion and a molecule of a solvent. 2. A method of hydrogenating a substrate , comprising exposing the substrate and a catalyst to hydrogen gas , wherein the catalyst comprises:{'br': None, 'sub': 'n', 'CpM(N—N)L;'}wherein Cp is a substituted or unsubstituted cyclopentadienyl ligand;wherein M is selected from the group consisting of Ir and Rh;wherein N—N is a substituted or unsubstituted bidentate ligand selected from the group consisting of a bipyridine ligand and a phenanthroline ligand;wherein n is 0 or 1; andwherein when n is 1 L is selected from the group consisting of an anion and a molecule of a solvent.325-. (canceled)27. A method of forming methanol and methyl formate , comprising contacting formic acid with a catalyst comprising:{'br': None, 'sub': 'n', 'CpM(N—N)L;'}wherein Cp is a substituted or unsubstituted cyclopentadienyl ligand;wherein M is selected from the group consisting of Ir and Rh;wherein N—N is a substituted or unsubstituted bidentate ligand selected from the group consisting of a bipyridine ligand and a phenanthroline ligand;wherein n is 0 or 1; andwherein when n is 1 L is selected from the group consisting of an anion and a molecule of a solvent.28. The method of claim 26 , wherein the contacting step takes place under acidic conditions.2932-. (canceled)33. The ...

Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable, of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Novel Catalyst Complex and Use Thereof in Alkane Oligomerization

Provided is a Group 9 novel metal catalyst complex further comprising a ketone-containing cocatalyst. The metal catalyst complex is useful in generating olefins from alkanes with great efficiency. In one embodiment, provided is an iridium catalyst complex useful in the dehydrogenation of alkanes comprising a ketone-containing cocatalyst and iridium complexed with a tridentate ligand. Also provided is a novel dehydrogenation method which utilizes the catalyst composition. In other embodiments, a novel process for preparing oligomers from alkanes utilizing the catalyst composition is provided. 18.-. (canceled)10. The method of wherein the ligand is 2 claim 9 ,6-bis(di-iso-propylphosphino)phenyl-1.11. The method of claim 9 , wherein the reaction is run with a high boiling alkane having a boiling point of at least 200° C. claim 9 , in an open reactor.12. The method of claim 11 , wherein the alkane is a Cor higher alkane.13. The method of claim 9 , wherein the dehydrogenation reaction is run in the presence of oxygen.14. The method of claim 9 , wherein the reaction is run in a closed system.15. The method of claim 14 , wherein the reaction is run with an alkane which is lower than a Calkane.16. The method of claim 9 , wherein an olefin product is recovered.17. The method of claim 13 , wherein the contacting is conducted in the gaseous phase.18. The method of claim 13 , wherein an olefin product is further reacted within the reactor system.19. A process for preparing oligomers from an alkane claim 13 , comprising{'claim-ref': {'@idref': 'CLM-00009', 'claim 9'}, '(a) contacting an alkane under dehydrogenation conditions in accordance with the method of to form olefins,'}(b) contacting the olefins prepared in step (a) under oligomerization conditions with an oligomerization catalyst to prepare oligomers of the olefins, and(c) hydrogenating the olefin oligomers,with all reactions occurring in a single reactor.20. The process of claim 19 , wherein the oligomerization catalyst ...

CATALYTIC SYNTHESIS OF SUPER LINEAR ALKENYL ARENES USING RHODIUM CATALYSTS

Catalytic methods for synthesis of super linear alkenyl arenes and alkyl arenes are provided. The methods are capable of synthesizing super linear alkyl and alkenyl arenes from simple arene and olefin starting materials and with high selectivity for linear coupling. Methods are also provided for making a 2,6-dimethylnapthalene (DMN) or 2,6-methylethylnapthalene (MEN). 1. A method of making alkenyl arenes , the method comprising contacting an arene and an olefin in the presence of an effective amount of a rhodium catalyst and an oxidant at an elevated temperature for a period of time to produce the alkenyl arenes.215-. (canceled)16. The method according to claim 1 , wherein a linear to branched ratio (L:B ratio) of the alkenyl arenes is about 2:1 to about 99:1.17. The method according to claim 1 , wherein the arene is a mono-substituted benzene; andwherein the alkenyl arenes comprise one or both of a meta-substituted alkenyl arene and a para-substituted alkenyl arene.18. The method according to claim 17 , wherein a total amount of the meta-substituted alkenyl arene and the para-substituted alkenyl arene is about 85 mol % to about 100 mol % based upon a total amount of the alkenyl arene.19. The method according to claim 17 , wherein the mono-substituted benzene comprises one or more of toluene claim 17 , chlorobenzene claim 17 , and anisole.20. The method according to claim 17 , wherein the olefin comprises one or more of propylene claim 17 , 1-pentene claim 17 , neohexene claim 17 , and isobutylene.21. The method according to claim 17 , wherein the olefin comprises a linear or branched claim 17 , substituted or unsubstituted alpha olefin having from 3 to about 30 carbon atoms.225915. The method according to any one of - and - claims 1 , wherein the arene comprises a polyaromatic.23. The method according to claim 22 , wherein the polyaromatic is selected from the group consisting of substituted and unsubstituted naphthalene claim 22 , anthracene claim 22 , tetracene ...

CHIRAL SPIRO PHOSPHORUS-NIROGEN-SULPHUR TRIDENTATE LIGAND, PREPARATION METHOD AND APPLICATION THEREOF

The present invention relates to a chiral spiro phosphine-nitrogen-sulfur (P—N—S) tridentate ligand, preparation method and application thereof. The P—N—S tridentate ligand is a compound represented by Formula I or Formula II, their racemates, optical isomers, or catalytically acceptable salts thereof. The ligand has a primary structure skeleton characterized as a chiral spiro indan skeleton structure with a thio group. The chiral spiro phosphine-nitrogen-sulfur tridentate ligand can be synthesized by reacting racemic or optical active compound 7-diary/alkyl phosphine-7′-amino-1,1′-spiro-dihydro-indene compound having a spiro-dihydro-indene skeleton as the starting material. The chiral spiro P—N—S tridentate ligand being complex with transition metal salt can be used in an asymmetric catalytic hydrogenation reaction for catalyzing carbonyl compound. In particular, in asymmetric hydrogenation reaction process, being complex with iridium for catalyzing β-alkyl-β-keto ester can obtain a high catalytic activity (a catalyst amount of 0.0002% mol) and high enantioselectivity (up to 99.9% ee) result. So the present invention has a practical value for industrial and commercial production. 4. A method for synthesizing the chiral spiro phosphine-nitrogen-sulfur tridentate ligand according to claim 2 , wherein claim 2 , comprising the following steps: the compound of Formula 1 is firstly reacted with the compound of Formula 2 (X is neither H nor OH) in a reactor for 2˜24 hours in the presence of an organic solvent and an alkali to obtain the compound shown as Formula 3; the compound of Formula 3 is then reduced to obtain the chiral spiro phosphine-nitrogen-sulfur tridentate ligand having the structure of Formula I; or the compound of Formula 1 is reacted with the compound of Formula 2 (X is H) in a reactor for 2˜24 hours in the presence of organic solvent and reducing agent directly to obtain the chiral spiro phosphine-nitrogen-sulfur tridentate ligand having the structure of ...

Method for producing optically active tetrahydroquinolines

Provided are a novel chiral iridium(III) complex; and a method for producing optically active 2-substituted-1,2,3,4-tetrahydroquinolines from 2-substituted-quinolines with the use of the chiral iridium(III) complex through a more economical and easy production process. The disclosed method for producing optically active 2-substituted-1,2,3,4-tetrahydroquinolines comprises reducing a quinoline compound represented by formula [I]: in the presence of a hydrogen donor compound and an iridium (III) complex having a chiral prolinamide compound as a ligand to give an optically active 2-substituted-1,2,3,4-tetrahydroquinoline represented by formula [II]:

Molybdenum Containing Hydrosilylation Reaction Catalysts and Compositions Containing the Catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition ′ capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

METHOD FOR PREPARING FORMAMIDE COMPOUNDS VIA HYDROGENATION OF CARBON DIOXIDE CATALYZED BY POROUS MATERIALS

A method for preparing formamide compounds via hydrogenation of carbon dioxide catalyzed by porous materials includes the following steps: by taking porous organometallic polymers as catalysts, reacting amine compounds with carbon dioxide and hydrogen under an air atmosphere to prepare formamide compounds. The method has the advantages of high reaction efficiency, good selectivity, mild conditions, economy, environmental protection, and simple operation. The catalysts are solid organometallic polymers with large specific surface area, strong carbon dioxide adsorption, hierarchical pore distribution, and uniformly dispersed metal centers. They are designed and synthesized as the reaction catalysts by changing the proportion of the cross-linked comonomer. The catalysts can be especially used for catalytic synthesis of fine chemical N, N-dimethylformamide (DMF) without addition of any additional solvent, alkali, or other additives, which is convenient for separation and purification of DMF. 2. The method according to claim 1 , wherein a molar ratio of the organic amine compound (I) to the catalyst (V) is (1 claim 1 ,000-100 claim 1 ,000):1;the predetermined reaction temperature is 80-150° C., and the predetermined reaction time is 2-160 hours.3. The method according to claim 1 , wherein the predetermined pressure of the hydrogen gas is controlled at 5-40 atm claim 1 , and the predetermined pressure of the carbon dioxide is controlled at 5-40 atm.4. The method according to claim 1 , wherein the reaction is carried out in at least one organic solvent selected from the group consisting of: DMF claim 1 , tetrahydrofuran claim 1 , 2-methyltetrahydrofuran claim 1 , dioxane claim 1 , glycol dimethyl ether claim 1 , tert-butyl methyl ether claim 1 , benzene claim 1 , methylbenzene claim 1 , xylene claim 1 , methanol claim 1 , ethanol claim 1 , isopropanol claim 1 , and tert-butanol.5. The method according to claim 1 , wherein when the organic amine compound (I) is ...

CATALYTICALLY HIGHLY EFFECTIVE PRECIOUS METAL-CARBOXYLATE COMPOUNDS OF IR, RU, RH, PD AND AU

Processes produce catalytically highly effective noble metal carboxylate compounds or their solutions that comprise A) a noble metal carboxylate, wherein the noble metal is selected from the group consisting of ruthenium, platinum, palladium, rhodium and gold, and B) at least one compound selected from the group consisting of oxalic acid, a salt of oxalic acid, a derivative of oxalic acid and a salt of the derivative of oxalic acid. The process digests the noble metal with alkaline earth peroxide to produce a digestion mass and dissolves the digestion mass in a carboxylic acid or a carboxylic acid diluted with a protic solvent to produce a resulting solution, whereby alkaline earth ions are separated off as salt of an oxalic acid or salt of oxalic acid derivatives, and the processes do not include any BaSO4 precipitation and filtration of barium sulphate. 2. The process according to claim 1 , wherein the noble metal is ruthenium or iridium.3. The process according to claim 1 , wherein the carboxylic acid is acetic acid.4. The process according to claim 1 , wherein the noble metal carboxylate is a noble metal acetate.5. The process according to claim 1 , wherein the alkaline earth ions are selected from the group consisting of Calcium claim 1 , Barium and Strontium.6. The process according to claim 1 , wherein the protic solvent is water or an alcohol. The present application is a continuation of U.S. patent application Ser. No. 14/294,672, filed Jun. 3, 2014, which is a divisional of U.S. patent application Ser. No. 12/531,795, filed Nov. 18, 2009, which is an application filed under 35 U.S.C. § 371 of PCT/EP2008/002186, filed Mar. 19, 2008, which claims foreign priority benefit under 35 U.S.C. § 119 of the German Patent Application No. 10 2007 014 914.1 filed Mar. 26, 2007.The invention relates to catalytically highly effective noble metal carboxylate compounds of Ir, Ru, Rh, Pd, Pt and Au and to processes for their production.A known use of iridium, ruthenium and ...

SELECTIVE PARTIAL HYDROGENATION OF TERPENES USING AN IRIDIUM-BASED CATALYST

A process for selective partial hydrogenation of conjugated diene compounds includes at least one, preferably terminal, diene function and at least one additional carbon-carbon double bond, the process including reacting the conjugated diene compounds with hydrogen in the presence of an iridium-NHC based catalyst. The disclosure also relates to a reaction mixture that can be obtained at the end of the process. The disclosure also relates to the use of the reaction mixture. 1. A process for partial hydrogenation of conjugated diene compounds comprising at least one conjugated diene function and at least one additional carbon-carbon double bond , the process comprising reacting the conjugated diene compounds with hydrogen in the presence of an Iridium-NHC based catalyst , to produce a reaction mixture comprising partially hydrogenated compounds.2. The process according to claim 1 , wherein the at least one conjugated diene function is a terminal conjugated diene function.3. The process according to claim 1 , wherein a portion of the partially hydrogenated compounds results from mono-hydrogenation of one carbon-carbon double bond of the conjugated diene function.4. The process according to claim 1 , wherein a portion of the partially hydrogenated compounds results from di-hydrogenation of two carbon-carbon double bonds of the conjugated diene function.5. The process according to claim 1 , wherein the conjugated diene compounds comprising at least one conjugated diene function and at least one additional carbon-carbon double bond are selected from terpenes.6. The process according to claim 1 , wherein the hydrogenation is performed at a temperature ranging from 10° C. to 120 ° C.7. The process according to claim 1 , wherein the hydrogenation is performed at a pressure ranging from 2 bars to 12 bars.8. The process according to claim 1 , wherein the reaction mixture comprises mono-hydrogenated compounds wherein a mono-hydrogenated compound resulting from the hydrogenation ...

Dehydrogenation Catalyst for Formic Acid, Method for Producing Hydrogen, and Method for Producing Deuterium Gas or Deuterated Hydrogen

To provide a catalyst for dehydrogenation of formic acid which allows hydrogen, heavy hydrogen gas or heavy-hydrogenated hydrogen containing no carbon monoxide to be produced through dehydrogenation of formic acid in a highly efficient manner. 2. The catalyst for dehydrogenation of formic acid according to claim 1 , wherein Mand Meach independently denote iridium claim 1 , rhodium claim 1 , ruthenium claim 1 , cobalt claim 1 , osmium claim 1 , nickel claim 1 , iron claim 1 , palladium or platinum.3. The catalyst for dehydrogenation of formic acid according to claim 1 , wherein Mand Mdenote iridium.4. The catalyst for dehydrogenation of formic acid according to claim 1 , wherein Land Leach independently denote pentamethylcyclopentadienyl or hexamethylbenzene.5. The catalyst for dehydrogenation of formic acid according to claim 1 , wherein Yand Yeach independently denote a water molecule claim 1 , a hydrogen atom claim 1 , a heavy hydrogen atom claim 1 , an alkoxide ion claim 1 , a hydroxide ion claim 1 , a halide ion claim 1 , a carbonate ion claim 1 , a trifluoromethanesulfonate ion claim 1 , a sulfate ion claim 1 , a nitrate ion claim 1 , a formate ion claim 1 , or an acetate ion claim 1 , or are absent.7. The catalyst for dehydrogenation of formic acid according to claim 6 , wherein all of Qto Qdenote carbon atoms.8. The catalyst for dehydrogenation of formic acid according to claim 6 , wherein all of Rto Rdenote hydrogen atoms.11. A method for dehydrogenating formic acid claim 6 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'allowing a solution containing formic acid and/or a formic acid salt to react in the presence of the catalyst for dehydrogenation of formic acid according to , to thereby dehydrogenate formic acid.'}12. A method for producing hydrogen gas (H) through dehydrogenation of formic acid claim 6 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'sub': '2', 'allowing a solution containing formic acid and/or a formic acid ...

HYDROFORMYLATION METHOD

A hydroformylation method including preparing an aldehyde by reacting a raw-C5 feed with a synthetic gas in the presence of a catalyst composition. 1. A hydroformylation method , the method comprising:reacting a raw-C5 feed with a synthetic gas in the presence of a catalyst composition to produce an aldehyde, {'br': None, 'M(L1)x(L2)y(L3)z\u2003\u2003[Chemical Formula 11]'}, 'wherein the catalyst composition comprises a phosphorous-based ligand, a transition metal compound of Chemical Formula 1, and a solventwherein in Chemical Formula 1,M is selected from the group consisting of rhodium (Rh), cobalt (Co), iridium (Ir), ruthenium (Ru), iron (Fe), nickel (Ni), palladium (Pd), platinum (Pt) and osmium (Os);L1, L2 and L3 are the same as or different from each other, and are each independently selected from the group consisting of hydrogen, carbonyl (CO), cyclooctadiene, norbornene, chlorine, triphenylphosphine (TPP) and acetylacetonato (AcAc); andx, y and z are each independently an integer of 0 to 5, and x, y and z are not 0 at the same time;wherein the solvent comprises one or more selected from the group consisting of tetraethylene glycol dimethyl ether (TEGDME), 1,2,4-trimethylbenzene and cumene; andwherein the raw-C5 feed has a total weight ratio of less than 1,000 and the solvent has a total weight ratio of 500 or greater, based on a total weight of the transition metal compound.2. The hydroformylation method of claim 1 , wherein the raw-C5 feed is a product of a naphtha cracking center (NCC) process claim 1 , and the raw-C5 feed comprises a mixture of a terminal monoene claim 1 , an internal monoene and a diene.3. The hydroformylation method of claim 2 , wherein claim 2 , an amount of the diene in the raw-C5 feed is 30% by weight or more based on a total weight of the mixture of the terminal monoene claim 2 , internal monoene and diene.4. The hydroformylation method of claim 1 , wherein the phosphorous-based ligand comprises one or more selected from the group ...

Novel isocyanide compound and hydrosilylation reaction catalyst

A hydrosilylation reaction catalyst prepared from a catalyst precursor comprising a transition metal compound of groups 8, 9, or 10 of the periodic table, excluding platinum, such as an iron carboxylate, cobalt carboxylate, or nickel carboxylate, and a ligand comprising an isocyanide compound having an organosiloxane group.

PROCESS OF ASYMMETRIC HYDROGENATION OF KETALS AND ACETALS

The present invention relates to a process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex. This process yields chiral compounds in a very efficient way and is very advantageous in that the amount of iridium complex can be remarkably reduced. 1. A process of the asymmetric hydrogenation of a ketal of an unsaturated ketone or an acetal of an unsaturated aldehyde by molecular hydrogen in the presence of at least one chiral iridium complex to yield a ketal or acetal having at least one stereogenic carbon centre.2. The process according to wherein the ketal or acetal is obtained from the reaction of the corresponding unsaturated ketone or the corresponding unsaturated aldehyde and an alcohol claim 1 , particularly a monol or a diol claim 1 , preferably an alcohol which is halogenated C-C-alkyl alcohol or which is selected from the group consisting of ethane-1 claim 1 ,2-diol claim 1 , propane-1 claim 1 ,2-diol claim 1 , propane-1 claim 1 ,3-diol claim 1 , butane-1 claim 1 ,4-diol claim 1 , butane-1 claim 1 ,3-diol claim 1 , butane-1 claim 1 ,2-diol claim 1 , butane-2 claim 1 ,3-diol claim 1 , 2-methylpropane-1 claim 1 ,2-diol claim 1 , 2-methylpropane-1 claim 1 ,3-diol claim 1 , 2 claim 1 ,2-dimethylpropane-1 claim 1 ,3-diol claim 1 , 1 claim 1 ,2-dimethylpropane-1 claim 1 ,3-diol claim 1 , 3-methylpentane-2 claim 1 ,4-diol and 2-(hydroxymethyl)cyclohexanol claim 1 , benzene-1 claim 1 ,2-diol and cyclohexane-1 claim 1 ,2-diols.3. The process according to wherein the unsaturated ketone or unsaturated aldehyde is a ketone or an aldehyde having a carbon-carbon double bond in the α claim 1 ,β-position to the C═O group.4. The process according to wherein the unsaturated ketone or unsaturated aldehyde is a ketone or an aldehyde having a carbon-carbon double bond in the γ claim 1 ,δ-position to the C═O group.6. The process according to ...

Decarboxylative conjugate additions and applications thereof

Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside.

METAL-ORGANIC FRAMEWORKS CONTAINING NITROGEN-DONOR LIGANDS FOR EFFICIENT CATALYTIC ORGANIC TRANSFORMATIONS

Metal-organic framework (MOFs) compositions based on nitrogen donor-based organic bridging ligands, including ligands based on 1,3-diketimine (NacNac), bipyridines and salicylaldimine, were synthesized and then post-synthetically metalated with metal precursors, such as complexes of first row transition metals. Metal complexes of the organic bridging ligands could also be directly incorporated into the MOFs. The MOFs provide a versatile family of recyclable and reusable single-site solid catalysts for catalyzing a variety of asymmetric organic transformations. The solid catalysts can also be integrated into a flow reactor or a supercritical fluid reactor. 1. A method for preparing a crystalline and porous metal-organic framework (MOF) , wherein said crystalline and porous MOF comprises periodic repeats of a metal-based secondary building unit (SBU) and a nitrogen donor-based bridging ligand , said method comprising:providing a nitrogen donor-based bridging ligand; andcontacting the nitrogen donor-based bridging ligand with a first metal source to obtain the crystalline and porous MOF.2. The method of claim 1 , wherein the nitrogen donor-based bridging ligand is a derivative of one of the nitrogen donor moieties selected from the group comprising bipyridines claim 1 , phenanthrolines claim 1 , terpyridines claim 1 , salicylaldimines claim 1 , pyridylphenols claim 1 , 1 claim 1 ,3-diketimine (NacNac) claim 1 , and bis(oxazolines).3. The method of claim 1 , wherein the nitrogen donor-based bridging ligand is a derivative of a nitrogen donor moiety claim 1 , wherein the nitrogen donor moiety is substituted by one or more substituents selected from a carboxylate claim 1 , pyridine claim 1 , and/or phosphonate moiety.4. The method of claim 3 , wherein the nitrogen donor-based bridging ligand is a dicarboxylate claim 3 , a tricarboxylate claim 3 , a tetracarboxylate claim 3 , a bipyridine claim 3 , a tripyridine claim 3 , a tetrapyridine claim 3 , a diphosphonate claim 3 , ...

CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME

Catalysts and methods for transformation of glycerol and a carbon feedstock, such as CO, a carbonate salt or a bicarbonate salt, are described herein. Homogeneous catalysts include compounds of formula M[NHC-R-linker]aLbXc, where M is a transition metal, NHC is an N-heterocyclic carbene ligand, R is an alkyl or aryl group, linker is a polar group, L is a neutral ligand, X is an anionic ligand, a ranges from 1-3, b ranges from 0-3, and c ranges from 0-3. Heterogeneous catalysts include a solid support with a catalytically active compound immobilized on the solid support, where the catalytically active compound has the formula M[NHC-R-linker]aLbXc where M is a transition metal, NHC is an N-heterocyclic carbene ligand, R is an alkyl or aryl group; linker is a polar group, L is a neutral ligand, X is an anionic ligand, a ranges from 1-3, b ranges from 0-3, and c ranges from 0-3. 1. A catalyst for the transformation of glycerol and any one CO , a carbonate salt and a bicarbonate salt , the catalyst comprising a catalytically active compound , or salt thereof , of formula (1):{'br': None, 'sub': a', 'b', 'c, 'M[NHC-R-linker]LX\u2003\u2003(I)'} M is a transition metal;', 'NHC is an N-heterocyclic carbene ligand;', 'R is an alkyl or aryl group;', 'linker is a polar group;', 'L is a neutral ligand;', 'X is an anionic ligand;', 'a is an integer ranging from 1 to 3;', 'b is an integer ranging from 0 to 3; and', 'c is an integer ranging from 0 to 3., 'where'}2. The catalyst of claim 1 , further comprising a solid support claim 1 , wherein the catalytically active compound is immobilized to the solid support.3. The catalyst of claim 2 , wherein the catalytically active compound is immobilized to the solid support viaionic or Coulombic interactions; ora covalent bond; oran indirect bond via a secondary linking compound, the secondary linking compound covalently bonded with both of the linker and the solid support.45-. (canceled)6. The catalyst of claim 2 , wherein the solid ...

INTEGRATED METHODS FOR CHEMICAL SYNTHESIS

Among other things, the present invention encompasses the applicant's recognition that epoxide carbonylation can be performed industrially utilizing syngas streams containing hydrogen, carbon monoxide and varying amounts carbon dioxide. Contrary to expectation, the epoxide carbonylation reaction proceeds selectively in the presence of these mixed gas streams and incorporates excess CO in the syngas stream into valuable chemical precursors, resulting in hydrogen streams substantially free of CO. This is economically and environmentally preferable to performing WSGR which releases the excess carbon as CO2. The integrated processes herein therefore provide improved carbon efficiency for processes based on coal or biomass gasification or steam methane reforming. 1. A method for the integrated production of chemicals comprising the steps of:a) in a first reaction zone, contacting an epoxide in the presence of a carbonylation catalyst with a syngas stream containing hydrogen and carbon monoxide thereby causing carbon monoxide in the industrial gas stream to react with the epoxide to provide an epoxide carbonylation product,b) removing an upgraded gas stream from the first reaction zone wherein the upgraded gas stream has a higher hydrogen to carbon monoxide than the starting syngas stream, andc) in a second reaction zone, utilizing the upgraded gas stream to conduct a second chemical process requiring a hydrogen to CO ratio higher than the ratio in the industrial gas stream utilized in step (a).2. The method of claim 1 , wherein the syngas stream has a molar hydrogen to CO ratio between 0.5:1 and 1.2:1 claim 1 , and the upgraded gas stream has a hydrogen to CO ratio of at least 1.9:1.3. The method of claim 1 , wherein the second chemical process comprises Fischer Tropsch synthesis.4. The method of claim 1 , wherein the second chemical process comprises reaction on a fuel cell.5. The method of claim 1 , wherein the second chemical process comprises hydrogenation.6. The ...

Method for producing fluorinated compound

An object of the present invention is to provide a novel method for producing a fluorine-containing methylene compound. The above object can be achieved by a method for producing a compound represented by formula (1):wherein R1 represents an organic group, RA represents hydrogen or fluorine, R4a represents hydrogen or an organic group, R4b represents hydrogen or an organic group, R5a represents hydrogen or an organic group, R5b represents hydrogen or an organic group, and R2 represents hydrogen or an organic group; R2 is optionally connected to R4a to form a ring; the method comprising step A of reacting a compound represented by formula (2):wherein X1 represents a leaving group, and other symbols are as defined above, with a compound represented by formula (3):wherein X2 represents a leaving group, and other symbols are as defined above, in the presence of a reducing agent as desired, under light irradiation.

PROCESS FOR THE PREPARATION OF DEUTERATED ETHANOL FROM D2

The invention relates to a process for the preparation of a deuterated ethanol from an acetic acid, an acetate, or an amide by reaction with Din the presence of a transition metal catalyst. 2. (canceled)3. The process of claim 1 , wherein the process has a conversion to compound (I) of at least 90%.4. The process of claim 1 , wherein compound (II) is an acetate selected from: methyl acetate claim 1 , n-propyl acetate claim 1 , i-propyl acetate claim 1 , n-butyl acetate claim 1 , i-butyl acetate claim 1 , di(propylene glycol) methyl ether acetate claim 1 , phenyl acetate claim 1 , ethylene glycol diacetate claim 1 , propylene glycol diacetate claim 1 , and glyceryl triacetate.5. The process of claim 1 , wherein compound (II) is an acetate represented by the formula CHCOOR claim 1 , wherein an alcohol made from Rrepresented by ROH is a primary or a secondary alcohol.6. The process of claim 1 , wherein compound (II) is methyl acetate.7. (canceled)9. The process of claim 8 , wherein the catalyst is of formula (V).10. The process of claim 9 , wherein compound (II) is selected from: methyl acetate claim 9 , n-propyl acetate claim 9 , i-propyl acetate claim 9 , n-butyl acetate claim 9 , i-butyl acetate claim 9 , and glyceryl triacetate.11. The process of claim 9 , wherein compound (II) is methyl acetate.12. The process of claim 9 , wherein the reaction is performed in the presence of a base.13. The process of claim 12 , wherein the base is NaBH.14. The process of claim 13 , wherein compound (II) is selected from: methyl acetate claim 13 , n-propyl acetate claim 13 , i-propyl acetate claim 13 , n-butyl acetate claim 13 , i-butyl acetate claim 13 , and glyceryl triacetate.15. The process of claim 13 , wherein compound (II) is methyl acetate.16. The process of claim 8 , wherein the catalyst is of formula (VI).17. The process of claim 16 , wherein compound (II) is selected from: methyl acetate claim 16 , n-propyl acetate claim 16 , i-propyl acetate claim 16 , n-butyl acetate ...

AN IMPROVED LED BASED PHOTOCHEMICAL REACTOR

The present invention provides an improved photochemical rector assembly device, particularly a light emitting diode (LED) based small photochemical reactor and methods for performing the photochemical transformations using the instantly presented device. Accordingly, the present invention relates to an improved photochemical transformation reaction by exposing the reaction mixture to a photochemical rector device as shown in fig. A-G, comprising of (i) light emitting diode (LED) panel (), (ii) Aluminium based heat sink, and (iii) cooling fan. 1. A photochemical rector device assembly as shown in Figures: A-G;comprising of{'b': '1', '(a) light source ();'}{'b': '3', '(b) heat dissipation assembly (); and'}{'b': '4', '(c) cooling assembly ().'}21. The device according to the claim 1 , wherein the light source () is a light emitting diode (LED) panel having wavelength selected from Violet (395-430 nm) claim 1 , Indigo (430-450 nm) claim 1 , Blue (450-480 nm) claim 1 , Blue-Green (480-520 nm) claim 1 , Green (520-555 nm) claim 1 , Yellow-Green (555-585 nm) claim 1 , Yellow (585-600 nm) claim 1 , Amber (600-615 nm) claim 1 , Orange (615-625 nm) claim 1 , Orange-Red (625-640 nm) and/or Red (640-700 nm).33. The device according to the claim 1 , wherein the heat dissipation assembly () is an aluminium based heat sink.44. The device according to the claim 1 , wherein the cooling assembly () is a cooling fan.8. The process according to claim 5 , wherein the catalyst is a photocatalyst selected from [4 claim 5 ,4′-Bis(tert-butyl)-2 claim 5 ,2′-bipyridine]bis[3 claim 5 ,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl]phenyl]iridium(III) hexafluorophosphate (Ir[dF(CF)ppy](dtbbpy)PF6).9. The process according to 6 claim 5 , wherein the catalyst is a photocatalyst selected from [4 claim 5 ,4′-Bis(tert-butyl)-2 claim 5 ,2′-bipyridine]bis[3 claim 5 ,5-difluoro-2-[5-(trifluoromethyl)-2-pyridinyl] phenyl]iridium(III) hexafluorophosphate (Ir[dF(CF)ppy]2(dtbbpy)PF6).10. The process ...

PROCESS FOR PRODUCTION OF D-SORBITOL

The present invention relates to a new process for the production of D-sorbitol. 2. A process according to claim 1 , wherein the transition metal of the transition metal based complex is selected from the group consisting of Ru claim 1 , Ir claim 1 , Pd claim 1 , Pt claim 1 , Rh claim 1 , Fe claim 1 , Os claim 1 , Ni claim 1 , and Co.3. A process according to claim 2 , wherein the transition metal of the transition metal based complex is selected from the group consisting of Ru and Ir.4. A process according to claim 1 , wherein the transition metal based complex comprises at least one organic ligand.6. A process according to claim 1 , wherein the process is carried out in at least one solvent.7. A process according to claim 6 , wherein the process is carried out in at least one non-aqueous claim 6 , organic or polar solvent.8. A process according to claim 1 , wherein the process is carried out in the presence of Hgas.9. A process according to claim 1 , wherein the process is carried out at a pressure of about 2 bar to about 200 bar claim 1 , preferably of about 5 bar to about 100 bar claim 1 , more preferably of about 10 bar to about 60 bar.10. A process according to claim 1 , which is carried out at a temperature in the range from about 20° C. to about 150° C. claim 1 , preferably from about 30° C. to about 100° C.11. A process according to claim 1 , which is carried out at a molar ratio of substrate to catalyst in the range of about 50 to about 100000 claim 1 , preferably of about 100 to about 40000 claim 1 , more preferably of about 5000 to about 30000.12. A process according to claim 1 , wherein the process is carried out in the presence of at least one base claim 1 , preferably at least one alkoxide base. The present invention relates to a new process for the production of sorbitol.D-Sorbitol, also known as D-glucitol, is a sugar alcohol with a sweet taste which the human body metabolizes slowly.D-Sorbitol, which IUPAC name is (2S,3R,4R,5R)-hexane-1,2,3,4,5,6- ...

Hydrosilylation Catalysts Made With Terdentate Nitrogen Ligands And Compositions Containing The Catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand. 115-. (canceled)17. The method of claim 16 , further comprising (2) combining the reaction product with an activator.1827-. (canceled)29. The composition of claim 28 , where the ruthenium metal compound is bis(2-methylallyl)(1 claim 28 ,5-cyclooctadiene) ruthenium(II).30. The composition of claim 28 , where each alkyl for A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , A claim 28 , and Ais independently selected from methyl claim 28 , ethyl claim 28 , propyl claim 28 , and butyl; each monovalent hydrocarbon group for Aand Ais independently selected from alkyl claim 28 , alkenyl claim 28 , carbocyclic claim 28 , aryl claim 28 , and aralkyl; and each monovalent heteroatom containing group for Aand Ais independently selected from halogenated hydrocarbon group or a hydrocarbonoxy group.33. The composition of claim 28 , where ingredient (C) is a silane of formula RSiH claim 28 , where subscript e is 0 claim 28 , 1 claim 28 , 2 claim 28 , or 3; subscript f is 1 claim 28 , 2 claim 28 , 3 claim 28 , or 4 claim 28 , with the proviso that a sum of (e+f) is 4 claim 28 , and each Ris independently a halogen atom or a monovalent organic group.34. The composition of claim 28 , where the composition further comprises one or more additional ingredients claim 28 , which are distinct from ingredients (A) claim 28 , (B) claim 28 , and (C) claim 28 , and which ...

METAL COMPLEX AND METHOD FOR PRODUCING HYDROGEN PEROXIDE

An object of the present invention is to provide a novel method for producing hydrogen peroxide by direct synthesis that is capable of taking the place of the conventional anthraquinone process, and to provide a catalyst used in the production method. 2: The metal complex according to claim 1 , wherein the number of carbon atoms of the alkyl group is 1 to 4 claim 1 , the number of carbon atoms of the aralkyl group is 7 to 10 claim 1 , the number of carbon atoms of the aryl group is 6 to 9 claim 1 , the number of carbon atoms of the alkoxy group is 1 to 4 claim 1 , the number of carbon atoms of the aralkyloxy group is 7 to 10 claim 1 , and the number of carbon atoms of the aryloxy group is 6 to 9.3: The metal complex according to claim 1 , represented by the formula (1) claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , Rand Rrepresent hydrogen atoms claim 1 , Rand Rrepresent methyl groups claim 1 , one of X claim 1 , Y and Z represents OH claim 1 , the remaining two represent HO claim 1 , and An1 represents a nitrate ion.4: The metal complex according to claim 1 , represented by the formula (2) claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , Rand Rrepresent hydrogen atoms claim 1 , Rand Rrepresent methyl groups claim 1 , Y represents HO and An2 represents a nitrate ion.5: The metal complex according to claim 1 , represented by the formula (3) claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , Rand Rrepresent hydrogen atoms claim 1 , Rand Rrepresent methyl groups claim 1 , Y represents HO and An3 represents a nitrate ion.6: The metal complex according to claim 1 , represented by the formula (4) claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , Rand Rrepresent hydrogen atoms claim 1 , Rand Rrepresent methyl groups claim 1 , X and Y represent HO and An4 represents a nitrate ion.8: The metal complex according to claim 1 , represented by the formula (1).9: The ...

Highly Robust Efficient Catalyst For Selective Dehydrogenation Of Neat Glycerol To Lactic Acid

A catalyst system includes a complex having formula I which advantageously has a sterically protecting N-heterocyclic carbene (NHC) carbene-pyridine ligand to handle harsh reactions conditions than many prior art catalysts: 2. The organometallic complex of wherein M is a metal selected from the group consisting of beryllium claim 1 , magnesium claim 1 , aluminum claim 1 , scandium claim 1 , titanium claim 1 , vanadium claim 1 , chromium claim 1 , manganese claim 1 , iron claim 1 , cobalt claim 1 , nickel claim 1 , copper claim 1 , zinc claim 1 , gallium claim 1 , germanium claim 1 , yttrium claim 1 , zirconium claim 1 , niobium claim 1 , molybdenum claim 1 , technetium claim 1 , ruthenium claim 1 , rhodium claim 1 , palladium claim 1 , silver claim 1 , cadmium claim 1 , indium claim 1 , tin claim 1 , antimony claim 1 , lanthanum claim 1 , cerium claim 1 , praseodymium claim 1 , neodymium claim 1 , promethium claim 1 , samarium claim 1 , europium claim 1 , gadolimium claim 1 , terbium claim 1 , dysprosium claim 1 , holmium claim 1 , erbium claim 1 , thalium claim 1 , ytterbium claim 1 , lutetium claim 1 , hafnium claim 1 , tantalum claim 1 , tungsten claim 1 , rhenium claim 1 , osmium claim 1 , iridium claim 1 , gold claim 1 , platinum claim 1 , thallium claim 1 , lead claim 1 , bismuth claim 1 , polonium claim 1 , thorium claim 1 , protactinium claim 1 , uranium claim 1 , neptunium claim 1 , and plutonium.3. The organometallic complex of wherein M is a transition metal selected from the group consisting of ruthenium claim 1 , rhodium claim 1 , iridium claim 1 , and iron.4. The organometallic complex of wherein M is iridium.5. The organometallic complex of wherein Ris mesityl claim 1 , methyl claim 1 , ethyl claim 1 , butyl claim 1 , n-propyl claim 1 , isopropyl claim 1 , n-butyl claim 1 , sec-butyl claim 1 , or t-butyl.6. The organometallic complex of wherein Ris mesityl or methyl.7. The organometallic complex of wherein Rare independently an optionally substituted ...

REMOVAL OF HOMOGENEOUS CATALYSTS FROM NMR/MRI AGENTS HYPERPOLARIZED VIA SABRE OR PHIP

The present disclosure provides a method that embodies a simple and effective route to remove homogeneous catalysts from solutions wherein NMR/MRI signal amplification by reversible exchange (SABRE) or parahydrogen-induced polarization (PHIP) is performed. A method for recovering a homogeneous SABRE/PHIP catalyst for reuse is also described. 1. A method of removing a homogeneous catalyst from a solution comprising the homogeneous catalyst and a hyperpolarized agent , the method comprising:contacting the solution comprising the homogeneous catalyst and the hyperpolarized agent with a catalyst removal agent, wherein the catalyst removal agent comprises a sulfur, nitrogen, or oxygen atom, and wherein the sulfur, nitrogen, or oxygen atom of the catalyst removal agent bonds with the homogeneous catalyst.2. The method of further comprising removing the catalyst removal agent bonded to the homogeneous catalyst from the solution thereby providing a purified solution comprising the hyperpolarized agent claim 1 , wherein the purified solution is substantially free of the homogeneous catalyst.3. The method of wherein the catalyst removal agent is an organic species.4. The method of wherein the sulfur claim 1 , nitrogen claim 1 , or oxygen atom of the catalyst removal agent contains at least one free binding site.5. The method of wherein the catalyst removal agent is functionalized on a solid-phase particle.6. The method of wherein the solid-phase particle comprises SiOor polystyrene.7. The method of wherein the solid-phase particle comprises SiO.8. The method of wherein the solid-phase particle comprises a bead comprising SiO.10. The method of wherein the contacting step comprises adding the catalyst removal agent to the solution.11. The method of wherein the contacting step comprises passing the solution through a separation apparatus containing the catalyst removal agent.12. The method of wherein the hyperpolarized agent maintains a hyperpolarized state in the purified ...

DEHYDROGENATION OF NEAT FORMIC ACID

A formic acid decomposition catalyst system includes organometallic complexes having formula 1: 121.-. (canceled)23. The organometallic complex of wherein M is a metal selected from the group consisting of beryllium claim 22 , magnesium claim 22 , aluminum claim 22 , scandium claim 22 , titanium claim 22 , vanadium claim 22 , chromium claim 22 , manganese claim 22 , iron claim 22 , cobalt claim 22 , nickel claim 22 , copper claim 22 , zinc claim 22 , gallium claim 22 , germanium claim 22 , yttrium claim 22 , zirconium claim 22 , niobium claim 22 , molybdenum claim 22 , technetium claim 22 , ruthenium claim 22 , rhodium claim 22 , palladium claim 22 , silver claim 22 , cadmium claim 22 , indium claim 22 , tin claim 22 , antimony claim 22 , lanthanum claim 22 , cerium claim 22 , praseodymium claim 22 , neodymium claim 22 , promethium claim 22 , samarium claim 22 , europium claim 22 , gadolimium claim 22 , terbium claim 22 , dysprosium claim 22 , holmium claim 22 , erbium claim 22 , thalium claim 22 , ytterbium claim 22 , lutetium claim 22 , hafnium claim 22 , tantalum claim 22 , tungsten claim 22 , rhenium claim 22 , osmium claim 22 , iridium claim 22 , gold claim 22 , platinum claim 22 , thallium claim 22 , lead claim 22 , bismuth claim 22 , polonium claim 22 , thorium claim 22 , protactinium claim 22 , uranium claim 22 , neptunium claim 22 , and plutonium.24. The organometallic complex of wherein M is a transition metal selected from the group consisting of ruthenium claim 22 , rhodium claim 22 , iridium claim 22 , and iron.25. The organometallic complex of wherein M is iridium.26. The organometallic complex of wherein R claim 22 , Rare each independently methyl claim 22 , ethyl claim 22 , butyl claim 22 , n-propyl claim 22 , isopropyl claim 22 , n-butyl claim 22 , sec-butyl claim 22 , t-butyl.27. The organometallic complex of wherein the Rare hydrogen.28. The organometallic complex of wherein Ris hydrogen claim 22 , methyl claim 22 , ethyl claim 22 , butyl claim 22 ...

CALIXARENE-BOUND IRIDIUM-CONTAINING METAL COLLOIDS

The invention provides complexes in which a calixarene-related compound is coordinated to an iridium-containing metal colloid. The complexes can be immobilized on a substrate. The complexes of the invention are useful as tunable and highly robust isolated metal colloids that find use in binding of molecules and catalysis of chemical reactions. 1. A complex comprising:(a) a metal colloid comprising a plurality of iridium atoms; and(b) a calixarene-related compound comprising a linker, wherein the linker comprises a coordinating atom coordinated to one of the plurality of iridium atoms.231-. (canceled)32. A metal colloid formed by a process comprising performing a reaction on the complex of claim 1 , wherein the reaction is selected from pyrolysis claim 1 , thermal decomposition claim 1 , oxidative decomposition and a combination thereof.3343-. (canceled)44. A catalytic process comprising reducing an organic molecule by contacting the organic molecule with (a) the complex of or the metal colloid of and (b) a reductant.45. The catalytic process of wherein the organic molecule is a substituted or unsubstituted alkyl.46. The catalytic process of wherein the reducing step comprises hydrogenation.4748-. (canceled) This application is a Continuation of U.S. application Ser. No. 13/502,590, now U.S. Pat. No. 8,969,607, which is a 371 National Stage entry of PCT/US2010/053818 filed Oct. 22, 2010 which claims under 35 USC 119(e)(1) the benefit of U.S. Application No. 61/254,163, filed Oct. 22, 2009, all of which are incorporated by reference in their entireties for all purposes.This invention relates to calixarenes and related compounds. More specifically, the invention relates to calixarenes and related compounds coordinated to an iridium-containing metal colloid through a linker component of the calixarene-related compound, which includes a coordinating atom coordinated to at least one iridium atom on the colloid. The resulting calixarene-bound colloids can be immobilized on ...

ALKANE DEHYDROGENATION PROCESS

Disclosed herein are processes for dehydrogenation of an alkane to an alkene using an iridium pincer complex. In the dehydrogenation reactions, hydrogen that is co-formed during the process must be removed for the chemical reaction to proceed and to prevent the excess hydrogen from poisoning the catalyst. In one embodiment the process comprises providing an alkane feedstock comprising at least one alkane and contacting the alkane with an iridium pincer complex in the presence of a hydrogen acceptor selected from the group consisting of ethylene, propene, or mixtures to form an alkene product. The processes disclosed herein can accomplish facile, low-temperature transfer dehydrogenation of alkanes with unprecedented selectivities and TONs at a reasonable rate of conversion. 1. A process for dehydrogenation of an alkane to an alkene , comprising:providing an alkane feedstock comprising at least one alkane; andcontacting the alkane with an iridium pincer complex in the presence of a hydrogen acceptor selected from the group consisting of ethylene, propene, or mixtures thereof to form an alkene product.2. The process of claim 1 , wherein the alkane is selected from the group consisting of a butane claim 1 , a pentane claim 1 , an octane claim 1 , a nonane claim 1 , a decane claim 1 , a dodecane claim 1 , and mixtures thereof.5. The process of claim 1 , wherein the iridium pincer complex is (PCP)Ir(CH) or (p-OK-PCP)Ir(CH).6. The process of claim 1 , wherein the iridium pincer complex is unsupported.7. The process of claim 1 , wherein the iridium pincer complex is immobilized on a solid support.8. The process of claim 7 , wherein the solid support is selected from the group consisting of silica claim 7 , γ-alumina claim 7 , basic alumina claim 7 , florisil claim 7 , and neutral alumina.9. The process of claim 8 , wherein the solid support is florisil or neutral alumina.10. The process of claim 1 , wherein the contacting is performed at a reaction temperature of less than ...

Catalyst Used for Dehydrogenation of Formic Acid, Method for Dehydrogenating Formic Acid, and Method for Producing Hydrogen

A catalyst including, as effective ingredient, complex represented by Formula (1) which contains bidentate ligand including aromatic heterocyclic 5-membered ring having 2 or more nitrogen atoms, or represented by Formula (2) which contains bidentate ligand including: aromatic heterocyclic 5-membered ring having 2 or more nitrogen atoms; and 6-membered ring having 1 or more nitrogen atoms, isomer or salt of the complex: 2. The catalyst used for a dehydrogenation reaction of at least one of formic acid and a formic acid salt according to claim 1 , wherein Mor Mdenotes iridium.3. The catalyst used for a dehydrogenation reaction of at least one of formic acid and a formic acid salt according to claim 1 , wherein Lor Ldenotes a pentamethylcyclopentadienyl ligand.4. The catalyst used for a dehydrogenation reaction of at least one of formic acid and a formic acid salt according to claim 1 , wherein Zor Zdenotes a water molecule claim 1 , a hydrogen atom claim 1 , an alkoxide ion claim 1 , a hydroxide ion claim 1 , a halide ion claim 1 , a carbonate ion claim 1 , a trifluoromethanesulfonate ion claim 1 , a sulfate ion claim 1 , a nitrate ion claim 1 , a formate ion claim 1 , or an acetate ion claim 1 , or is absent. The present invention relates to a catalyst used for dehydrogenation of formic acid, a method for dehydrogenating formic acid using the catalyst, and a method for producing hydrogen.Hydrogen (H) has been produced in an amount of about five hundred billion Nmall over the world. The hydrogen has attracted much attention as future clean energy as well as has been applied for a variety of uses such as refinement of oil or production of ammonia. For example, a fuel cell is capable of efficiently supplying electricity when the hydrogen is supplied externally thereto. However, the hydrogen is highly reactive gas, so that it is difficult to be transported and stored. Therefore, there has been a need for a safe and inexpensive transportation and storage technology in ...

Supported Metal Catalysts

The present invention relates to supported metal catalysts, wherein the catalysts are modified by at least one amine, a method for the preparation thereof and hydrogenation processes utilising the supported metal catalysts. 1. A supported metal catalyst , wherein the catalyst is modified by at least one amine , provided that when the metal is Pt and the support is AlO , the amine is not:a) S-benzyl-L-cysteine;b) N-benzyl-S-benzyl-L-cysteine;c) L-cysteine ethyl ester;d) S-benzyl-L-cysteine ethyl ester;e) N-benzyl-S-benzyl-L-cysteine ethyl ester;f) S-phenyl-L-cysteine ethyl ester; org) N-benzyl-S-phenyl-L-cysteine ethyl ester.2. The catalyst of claim 1 , wherein the support is carbon claim 1 , alumina claim 1 , calcium carbonate claim 1 , titania claim 1 , silica claim 1 , zirconia claim 1 , ceria claim 1 , or a combination thereof.3. The catalyst of claim 2 , wherein the alumina is alpha-AlO claim 2 , beta-AlO claim 2 , gamma-AlO claim 2 , delta-AlO claim 2 , theta-AlOor a combination thereof.4. The catalyst of claim 2 , wherein the carbon is activated carbon claim 2 , carbon black claim 2 , or graphite.5. The catalyst of claim 2 , wherein the carbon is Norit Carbon GSX claim 2 , Ceca L4S claim 2 , Ceca 2S claim 2 , Ceca CPL claim 2 , Timcal T44 Graphite claim 2 , or a combination thereof.6. The catalyst of claim 1 , wherein at least one metal is a Group VIII metal or Group IB metal.7. The catalyst of claim 1 , wherein the metal is ruthenium claim 1 , rhodium claim 1 , palladium claim 1 , osmium claim 1 , iridium claim 1 , platinum claim 1 , gold claim 1 , silver claim 1 , copper claim 1 , iron claim 1 , cobalt claim 1 , nickel claim 1 , or a combination thereof.8. The catalyst of claim 1 , wherein the metal is palladium claim 1 , platinum claim 1 , gold claim 1 , or a combination thereof.9. The catalyst of claim 1 , wherein the metal loading is from about 0.01 wt % to about 20 wt %.10. The catalyst of claim 1 , wherein the amine is a natural amino acid claim 1 , non ...

METHOD FOR THE PRODUCTION OF PRAZIQUANTEL AND PRECURSORS THEREOF

The present invention provides methods of preparing Praziquantel, in particular (R)-Praziquantel and analogues thereof in a stereoselective manner. One method involves asymmetric hydrogenation of the following intermediate compound 2. Method according to claim 1 , wherein R is methyl or cyclohexyl.3. Method according to claim 1 , wherein the mixture comprises either the compound according to Formula (X1) or the compound according to Formula (X2) in excess and wherein the hydrogenation step is an asymmetric hydrogenation step in the presence of a catalyst.4. Method according to claim 3 , wherein the compound according to Formula (X1) is present in the mixture in an enantiomeric excess of at least 10% claim 3 , preferably at least 20% claim 3 , more preferably at least 30% claim 3 , at least 40% claim 3 , at least 50% claim 3 , at least 60 claim 3 , at least 70% claim 3 , most preferably at least 80%.5. Method according to claim 3 , wherein the catalyst is an iridium based catalyst.6. Method according to claim 5 , wherein the catalyst comprises an iridium compound in combination with a chiral phosphine ligand.8. Method according to claim 3 , wherein the asymmetric hydrogenation step in the presence of a catalyst is carried out involving at least one of:elevated temperature, which temperature is preferably at least 60° C., for instance at least 80° C., at least 90° C. or at least 100° C.;a solvent selected from dioxane, THF, Me-THF, IPA, DCE, DCM, ethyl acetate, toluene, α,α,α-trifluorotoluene, xylene, preferably m-xylene or p-xylene, mesitylene or a mixture of any two or more thereof;{'sub': 2', '3', '4', '4, 'at least one additive, which is preferably selected from iodine (I), iodide, phosphoric acid (HPO), acetic acid (AcOH), HI, HBF, preferably in an amount of at least 5 mol %, more preferably at least 50 mol %, more preferably at least 100 mol %;'}a substrate concentration of at least 0.05 mmol/l, for instance at least 10 mmol/l, at least 100 mmol/l;a catalyst ...

Asymmetrical hydrogenation reaction of ketonic acid compound

The present invention relates to the technical field of organic chemistry, specifically an asymmetrical hydrogenation of an ∂-ketonic acid compound, the technical proposal being as shown by the following formula: 2. The preparation method according to claim 1 , wherein claim 1 , the molar dosage ratio of the said base to the substrate A compound is (1.001∥1.5):1.3. The preparation method according to claim 1 , wherein claim 1 , Ris a phenyl claim 1 , a substituted phenyl claim 1 , a naphthyl or a substituted naphthyl.4. The preparation method according to claim 1 , wherein claim 1 , R is 4-Bu.5. The preparation method according to claim 1 , wherein claim 1 , the said base is sodium hydroxide or potassium hydroxide.6. The preparation method according to any claims of 1 claim 1 , 3-5 claim 1 , wherein claim 1 , under the protection of nitrogen atmosphere claim 1 , at a hydrogen pressure of 0.5-10 MPa claim 1 , with a base dosage 1.0˜3.0 molar equivalent claim 1 , in the presence of organic solvent claim 1 , ∂-ketonic acid compound is formed into B compound in the catalytic of chiral spiro-pyridylamidophosphine ligand iridium complex (M) with the molar dosage 0.00001˜0.01 molar equivalent.7. The preparation method according to any claims of 1 claim 1 , 3-5 claim 1 , wherein claim 1 , under the protection of nitrogen atmosphere claim 1 , were added into the inner hydrogenation tube substrate A claim 1 , 1.0˜3.0 molar equivalent base claim 1 , chiral spiro-pyridylamidophosphine ligand iridium complex (M) with the molar dosage 0.00001˜0.01 molar equivalent and the solvent; The inner reaction tube was placed into the hydrogenation reactor at a hydrogen pressure of 0.5-10 MPa was filled; The reaction was stirred for 1-30 hours at a temperature of 10˜90° C. to obtain B compound; the base selected from sodium hydroxide claim 1 , potassium hydroxide claim 1 , sodium tert-butyl oxide or potassium tert-butyl oxide.8. The preparation method according to claim 1 , wherein claim 1 ...

CATALYST FOR ASYMMETRIC HYDROGENATION OF COMPOUND CONTAINING CARBON DOUBLE BOND

The present invention may provide an asymmetric hydrogenation catalyst capable of resolving enantiomers with excellent enantioselectivity from a carbon-carbon double bond-containing compound. The catalyst according to one embodiment of the present invention includes: an iridium cation; and a ligand bonded to the iridium cation. The present invention relates to a catalyst for asymmetric hydrogenation of a carbon-carbon double bond-containing compound. More specifically, the present invention relates to a catalyst for asymmetric hydrogenation that may be used to produce enantiomers from a carbon-carbon double bond-containing compound.Studies on methods of synthesizing a levorotatory enantiomer and a dextrorotatory enantiomer from a prochiral carbon-carbon double bond-containing compound by using asymmetric hydrogenation have attracted the attention of many researchers since the 1990s because of the usefulness and economics of these methods.As many studies on asymmetric hydrogenation have been conducted by various researchers, a great technological breakthrough development has been made, and these studies are still underway. Most of the technologies that make this possible have mainly used ruthenium metal or rhodium metal complex catalysts, and have resulted in a satisfactory asymmetric induction of 98% ee or more.Asymmetric hydrogenation reactions using these catalysts are as shown in the following Reaction Scheme 1 and Reaction Scheme 2:In Reaction Scheme 1 above, X represents OH, NH, NRH, COH, CONH, CONRor the like, and in Reaction Scheme 2 above, Y represents O, S, NH or the like. These carbon-carbon double bond-containing compounds generally have a polar functional group capable of bonding with the catalyst for asymmetric hydrogenation. Indeed, ruthenium metal or rhodium metal complex catalysts have shown poor reactivity in the asymmetric hydrogenation of carbon-carbon double bond-containing compounds containing no polar functional group.Meanwhile, as catalysts ...

COMPLEXES OF PHOSPHINE LIGANDS COMPRISING A CARBA-CLOSO-DODECABORATE SUBSTITUENT

This invention relates to complexes comprising phosphine ligands comprising a carbo-closo-dodecaborate substituent and transition metals as well as their use in catalytic reactions. 1. A composition comprising a transition metal and a phosphine ligand comprising at least one carba-closo-dodecaborate substituent.3. A composition comprising:a solvent selected from the group consisting of dimethoxy ethane, dioxane, pyridine, tetrahydrofuran, diethyl ether, benzene, toluene, acetonitrile, methylene chloride, chloroform, dimethyl formamide, and acetone;{'claim-ref': {'@idref': 'CLM-00002', 'claim 2'}, 'a ligand of ; and'}a transition metal selected from the group consisting of Fe, Ru, Os, Co, Rh, Ir, Ni, Pd, Pt, Cu, Ag, and Au.4. The composition of claim 3 , wherein the transition metal is selected from the group consisting of Fe claim 3 , Ru claim 3 , Co claim 3 , Ni claim 3 , and Pd.5. The ligand of claim 2 , wherein Ris a halogen selected from the group consisting of F claim 2 , Cl claim 2 , Br claim 2 , and I.6. The ligand of claim 2 , wherein A is selected from the group consisting of Li claim 2 , Na claim 2 , K claim 2 , Cs claim 2 , HN(alkyl) claim 2 , N(alkyl) claim 2 , Mg claim 2 , Ca claim 2 , and Zn.7. The ligand of claim 2 , wherein Ris H.8. The ligand of claim 2 , wherein Ris Cl.9. The ligand of claim 2 , wherein Ris Br.10. The ligand of claim 2 , wherein Ris I.11. The ligand of claim 2 , wherein Ris alkyl.12. The ligand of claim 2 , wherein Ris alkoxy.13. The ligand of claim 2 , wherein Ris siloxy.14. The ligand of claim 2 , wherein Rcomprises two or more different types of substituents selected from the group consisting of H claim 2 , halogen claim 2 , alkyl claim 2 , aryl claim 2 , silyl claim 2 , and alkoxy.15. The ligand of claim 2 , wherein Rcomprises combinations of H and halogen.1817. The complex of claim 2 , wherein Rand Rare isopropyl.1917. The complex of claim 2 , wherein n is 1.2017. The complex of claim 2 , wherein M is selected from the group ...

DEHYDROGENATION CATALYST, AND CARBONYL COMPOUND AND HYDROGEN PRODUCTION METHOD USING SAID CATALYST

Objects of the present invention are to provide a novel dehydrogenation reaction catalyst, to provide a method that can produce a ketone, an aldehyde, and a carboxylic acid with high efficiency from an alcohol, and to provide a method for efficiently producing hydrogen from an alcohol, formic acid, or a formate, and they are accomplished by a catalyst containing an organometallic compound of Formula (1). 2. The method according to claim 1 , wherein the oxygen-containing compound is an alcohol.3. The method according to claim 1 , wherein the oxygen-containing compound is formic acid or a formate.4. The method according to any one of to claim 1 , wherein L is an aquo ligand.5. The method according to any one of to claim 1 , wherein Ar is an optionally substituted cyclopentadienyl group claim 1 , and M is iridium.6. A dehydrogenation catalyst comprising an organometallic compound of Formula (1) claim 1 , wherein it is for use in the method according to any one of to .7. A method for producing a carbonyl compound claim 1 , wherein an alcohol is dehydrogenated by use of the dehydrogenation method according to any one of to to produce a corresponding carbonyl compound.8. The method according to claim 7 , wherein the carbonyl compound is a ketone or an aldehyde.9. The method according to claim 7 , wherein the alcohol is a primary alcohol claim 7 , the carbonyl compound is a carboxylic acid claim 7 , and a solvent comprising water is used.10. A method for producing hydrogen claim 7 , wherein hydrogen is prepared by dehydrogenation of an alcohol claim 7 , a mixture containing an alcohol and water claim 7 , formic acid claim 7 , or a formate using the dehydrogenation method according to any one of to .12. The organometallic compound according to claim 11 , wherein Ar is an optionally substituted cyclopentadienyl group claim 11 , and M is iridium.14. The organometallic compound according to claim 13 , wherein Ar is an optionally substituted cyclopentadienyl group claim 13 , ...

HYDROFORMYLATION CATALYST, COMPOSITION INCLUDING HYDROFORMYLATION CATALYST, AND METHOD OF PREPARING ALDEHYDE USING HYDROFORMYLATION CATALYST (As Amended)

A hydroformylation catalyst having excellent catalytic activity and stability, a composition including the hydroformylation catalyst, and a method of preparing an aldehyde using the hydroformylation catalyst, wherein, when hydroformylation of an olefin compound is performed in the presence of the hydroformylation catalyst to prepare an aldehyde, the normal/iso (n/i) ratio of the prepared aldehyde is lowered, and synthesis gas yield is increased. 2. The hydroformylation catalyst according to claim 1 , wherein a concentration of the transition metal compound represented by Formula 2 is 0.003 to 0.05 mole based on 1 mole of the phosphite ligand represented by Formula 1.3. The hydroformylation catalyst according to claim 1 , wherein the transition metal compound represented by Formula 2 is one or more selected from the group consisting of dicobalt octacarbonyl [Co(CO)] claim 1 , (acetylacetonato)dicarbonylrhodium [Rh(AcAc)(CO)] claim 1 , (acetylacetonato)carbonyl(triphenylphosphine)rhodium [Rh(AcAc)(CO)(TPP)] claim 1 , hydridocarbonyltris(triphenylphosphine)rhodium [HRh(CO)(TPP)] claim 1 , (acetylacetonato)dicarbonyliridium [Ir(AcAc)(CO)] claim 1 , and hydridocarbonyltris(triphenylphosphine)iridium [HIr(CO)(TPP)].4. The hydroformylation catalyst according to claim 1 , wherein the hydroformylation catalyst catalyzes hydroformylation of propylene to butyraldehyde.5. The hydroformylation catalyst according to claim 4 , wherein a molar ratio of n-butyraldehyde to isobutyraldehyde in the butyraldehyde prepared by catalysis of the hydroformylation catalyst is 2 or less.7. The hydroformylation catalyst composition according to claim 6 , wherein the solvent is one or more selected from the group consisting of propyl aldehyde claim 6 , butyraldehyde claim 6 , pentyl aldehyde claim 6 , valeraldehyde claim 6 , acetone claim 6 , methyl ethyl ketone claim 6 , methyl isobutyl ketone claim 6 , acetophenone claim 6 , cyclohexanone claim 6 , ethanol claim 6 , pentanol claim 6 , octanol ...

BIMETALLIC CATALYTIC COMPOUNDS AND COMPOSITIONS COMPRISING PERMETHYLPENTALENE LIGANDS

Bimetallic catalytic compounds and compositions comprising permethylpentalene ligands, as well as their methods of preparation, are described. The catalytic compounds and compositions are promising catalysts in olefin (e.g. ethylene) polymerisation reactions. 2. The compound of claim 1 , wherein each TM is independently selected from Rh claim 1 , Ir claim 1 , Ti claim 1 , Ni claim 1 , Co claim 1 , Fe and Zr.3. The compound of claim 1 , wherein both TM groups are the same.4. The compound of any of claim 1 , wherein each ring A is independently a 5-8 membered aryl claim 1 , heteroaryl containing 1 claim 1 , 2 or 3 heteroatoms selected from N claim 1 , O and S claim 1 , or partially unsaturated cycloalkyl that is:{'sub': x', 'y', 'x', 'y', '3, '1. optionally substituted with one or more substituents selected from (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl; (1-4C)alkoxy, aryl, aryloxy, halo, hydroxyl, nitro, —NRR, —C(O)NRRand —Si[(1-4C)alkyl], and/or'}{'sub': x', 'y', 'x', 'y', '3, 'claim-text': {'sub': x', 'y, 'wherein Rand Rare independently selected from H and (1-4C)alkyl.'}, '2. fused to one or more 5- or 6-membered aryl, heteroaryl, or partially unsaturated cycloalkyl rings, either or all of which being optionally substituted with one or more substituents selected from (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl; (1-4C)alkoxy, aryl, aryloxy, halo, hydroxyl, nitro, —NRR, —C(O)NRRand —Si[(1-4C)alkyl],'}5. The compound of claim 1 , wherein each ring A is independently a 5-8 membered aryl claim 1 , heteroaryl containing 1 or 2 N heteroatoms claim 1 , or partially unsaturated cycloalkyl that is:{'sub': x', 'y', 'x', 'y', '3, '1. optionally substituted with one or more substituents selected from (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl; (1-4C)alkoxy, aryl, aryloxy, halo, hydroxyl, nitro, —NRR, —C(O)NRRand —Si[(1-4C)alkyl], and/or'}{'sub': x', 'y', 'x', 'y', '3, 'claim-text': {'sub': x', 'y, 'wherein Rand Rare independently selected from H and (1-4C)alkyl.'}, '2. fused to ...

CATALYST, HYDROGENATION OF HYDROGEN CARBONATE, HYDROGEN STORAGE SYSTEM

The invention relates to a catalyst according to the formula IrCl(cod)(NHC)]+nP (n=2, 3 or 4), or [Ir(cod)(NHC)(P)]+nP (n=1, 2 or 3), which is suitable to decompose formates in an aqueous reaction system, and for the production of hydrogen gas free of COor hydrogenation of hydrogen carbonates, wherein Ir means iridium; Cl means chloro; cod means 1,5-cyclooctadiene; NHC means N-heterocyclic carbene, preferably 1-R-3-methylimidasolium chloride, wherein R means C1 to C5 alkyl and P means 1,3,5-triaza-7-phosphaadamantane (pta), monosulphonated triphenilphosphine (mtppms), trisulphonated triphenylphosphine (mtppts), or tetrasulphonated diphenylphosphynopropane (dpppts). Furthermore, the invention relates to a process for the preparation of the catalyst according to the invention. Further, the invention relates to a process for the decomposition of formate in aqueous reaction system, and for the production of hydrogen gas free of CO, still further, a process for the hydrogenation of hydrogen carbonate in an aqueous reaction system, as well as the production of the respective formate. Further, the invention relates to a process for the decomposition of formate according to the invention, and the hydrogenation of the hydrogen carbonate generated in the same reaction system. The invention relates to a hydrogen storage system based on the process according to the invention, preferably accumulator or fuel cell, and the use thereof. 1. A catalyst according to the general formula of [IrCl(cod)(NHC)]+nP , which is suitable for the decomposition of formates in an aqueous reaction system and for the generation of hydrogen gas (H) , which is free of COside products , or for the hydrogenation of hydrogen carbonates (HCO) , wherein in the formulaIr means iridium;Cl means chloro;cod means 1,5-cyclooctadiene;NHC means an N-heterocyclic carbene, preferably 1-R-3-methylimidazolium chloride, wherein R means C1 to C5 alkyl group, preferably C2 or C4 alkyl group;n means an integer with the ...

Process for producing alcohol analogue

Provided is a process for producing an optically active hydroxyaldehyde or aminohydroxyaldehyde. The process for producing an optically active hydroxyaldehyde or aminohydroxyaldehyde is characterized by reacting an aldehyde or an imine with a boric acid enol ester in the presence of a copper compound and an optically active bidentate phosphine compound.

DEHYDROGENATION OF NEAT FORMIC ACID

A formic acid decomposition catalyst system includes organometallic complexes having formula 1: 2. The organometallic complex of wherein M is a metal selected from the group consisting of beryllium claim 1 , magnesium claim 1 , aluminum claim 1 , scandium claim 1 , titanium claim 1 , vanadium claim 1 , chromium claim 1 , manganese claim 1 , iron claim 1 , cobalt claim 1 , nickel claim 1 , copper claim 1 , zinc claim 1 , gallium claim 1 , germanium claim 1 , yttrium claim 1 , zirconium claim 1 , niobium claim 1 , molybdenum claim 1 , technetium claim 1 , ruthenium claim 1 , rhodium claim 1 , palladium claim 1 , silver claim 1 , cadmium claim 1 , indium claim 1 , tin claim 1 , antimony claim 1 , lanthanum claim 1 , cerium claim 1 , praseodymium claim 1 , neodymium claim 1 , promethium claim 1 , samarium claim 1 , europium claim 1 , gadolimium claim 1 , terbium claim 1 , dysprosium claim 1 , holmium claim 1 , erbium claim 1 , thalium claim 1 , ytterbium claim 1 , lutetium claim 1 , hafnium claim 1 , tantalum claim 1 , tungsten claim 1 , rhenium claim 1 , osmium claim 1 , iridium claim 1 , gold claim 1 , platinum claim 1 , thallium claim 1 , lead claim 1 , bismuth claim 1 , polonium claim 1 , thorium claim 1 , protactinium claim 1 , uranium claim 1 , neptunium claim 1 , and plutonium.3. The organometallic complex of wherein M is a transition metal selected from the group consisting of ruthenium claim 1 , rhodium claim 1 , iridium claim 1 , and iron.4. The organometallic complex of wherein M is ruthenium.5. The organometallic complex of wherein R claim 1 , Rare each independently methyl claim 1 , ethyl claim 1 , butyl claim 1 , n-propyl claim 1 , isopropyl claim 1 , n-butyl claim 1 , sec-butyl claim 1 , t-butyl.6. The organometallic complex of wherein the Rare hydrogen.7. The organometallic complex of wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , Rare each independently hydrogen.8. The organometallic ...

Method for olefin hydroformylation reaction using solid heterogeneous catalyst

A method for an olefin hydroformylation reaction comprising subjecting olefins and CO/H2 mixed gas to the olefin hydroformylation reaction in a reactor in the presence of a solid heterogeneous catalyst, which consisting of a metal component and an organic ligand polymer with hierarchical porosity, in which the metal component is one or more of Rh, Ir or Co, the organic ligand polymer is a polymer formed by polymerization of an organic ligand monomer containing P and alkenyl group and optional N, and in the solid heterogeneous catalyst, the metal component forms coordinated bonds with the P atom or N in the backbone of the organic ligand polymer and exists in a monoatomic dispersion state; the reaction technique and device are simple, and the catalyst has a stable hydroformylation property with a high activity and yield.

PROCESS FOR THE PREPARATION OF DEUTERATED ETHANOL FROM D2O

The invention relates to a process for the preparation of a deuterated ethanol from ethanol, DO, a ruthenium catalyst, and a co-solvent. 2. The process of claim 1 , wherein the abundance of D in Rand Ris at least 80%.3. The process of claim 1 , wherein the abundance of D in R-Ris at most 50%.4. The process of claim 1 , wherein the abundance of D in Rand Ris at least 90% and the abundance of D in R-Ris at most 5%.6. The process of claim 5 , wherein the catalyst is of formula (III).7. The process of claim 5 , wherein the catalyst is of formula (III) and the reaction is performed in the presence of an alkali metal borohydride.8. The process of claim 7 , wherein the alkali metal borohydride is NaBH.9. The process of claim 8 , wherein the co-solvent is selected from tetrahydrofuran claim 8 , toluene claim 8 , 1 claim 8 ,4-dioxane claim 8 , diglyme and cyclopentyl methyl ether.10. The process of claim 5 , wherein the catalyst is of formula (III) and the reaction is performed in the presence of an alkali metal borohydride and in the absence of NaOH.11. The process of claim 10 , wherein the alkali metal borohydride is NaBH.12. The process of claim 11 , wherein the co-solvent is selected from tetrahydrofuran claim 11 , toluene claim 11 , 1 claim 11 ,4-dioxane claim 11 , diglyme and cyclopentyl methyl ether.13. The process of claim 5 , wherein the catalyst is of formula (IV).14. The process of claim 13 , wherein the co-solvent is selected from tetrahydrofuran claim 13 , toluene claim 13 , 1 claim 13 ,4-dioxane claim 13 , diglyme and cyclopentyl methyl ether.15. The process of claim 5 , wherein the catalyst is of formula (IV) and the reaction is performed in the absence of a base.16. The process of claim 15 , wherein the co-solvent is selected from tetrahydrofuran claim 15 , toluene claim 15 , 1 claim 15 ,4-dioxane claim 15 , diglyme and cyclopentyl methyl ether.17. The process of claim 1 , wherein the reacting step comprises claim 1 ,{'sub': '2', 'a) reacting a first portion ...

PROCESS FOR THE PREPARATION OF DEUTERATED ETHANOL FROM D2

The invention relates to a process for the preparation of a deuterated ethanol from an acetic acid, an acetate, or an amide by reaction with Din the presence of a transition metal catalyst. 2. The process of claim 1 , wherein the abundance of D in R-Ris at most 50%.3. The process of claim 1 , wherein the process has a conversion to compound (I) of at least 90%.4. The process of claim 1 , wherein compound (II) is an acetate selected from: methyl acetate claim 1 , n-propyl acetate claim 1 , i-propyl acetate claim 1 , n-butyl acetate claim 1 , i-butyl acetate claim 1 , di(propylene glycol) methyl ether acetate claim 1 , phenyl acetate claim 1 , ethylene glycol diacetate claim 1 , propylene glycol diacetate claim 1 , and glyceryl triacetate.5. The process of claim 1 , wherein compound (II) is an acetate represented by the formula CHCOOR claim 1 , wherein an alcohol made from Rrepresented by ROH is a primary or a secondary alcohol.6. The process of claim 1 , wherein compound (II) is methyl acetate.9. The process of claim 8 , wherein the catalyst is of formula (V).10. The process of claim 9 , wherein compound (II) is selected from: methyl acetate claim 9 , n-propyl acetate claim 9 , i-propyl acetate claim 9 , n-butyl acetate claim 9 , i-butyl acetate claim 9 , and glyceryl triacetate and the catalyst is of formula IV.11. The process of claim 9 , wherein compound (II) is methyl acetate.12. The process of claim 9 , wherein the reaction is performed in the presence of a base.13. The process of claim 12 , wherein the base is NaBH.14. The process of claim 13 , wherein compound (II) is selected from: methyl acetate claim 13 , n-propyl acetate claim 13 , i-propyl acetate claim 13 , n-butyl acetate claim 13 , i-butyl acetate claim 13 , and glyceryl triacetate and the catalyst is of formula IV.15. The process of claim 13 , wherein compound (II) is methyl acetate.16. The process of claim 8 , wherein the catalyst is of formula (VI).17. The process of claim 16 , wherein compound (II) ...

COMPOSITIONS AND METHODS FOR PREPARING BETA,GAMMA-UNSATURATED ACIDS

The present disclosure provides methods for enantioselective synthesis of acyclic α-quaternary carboxylic acid derivatives via iridium-catalyzed allylic alkylation. 2. (canceled)3. (canceled)5. (canceled)6. (canceled)10. The method of claim 1 , wherein the nucleophile is a masked acyl cyanide (MAC) nucleophile.12. (canceled)13. (canceled)14. The method of claim 1 , wherein the iridium catalyst is used in an amount from about 0.01 mol % to about 10 mol % relative to the compound of formula (II).1517-. (canceled)18. The method of claim 1 , wherein the iridium catalyst is prepared by combining an iridium source and a chiral ligand.19. The method of claim 18 , wherein the iridium source is selected from (acetylacetonato)(1 claim 18 ,5-cyclooctadiene)iridium(I) claim 18 , (acetylacetonato)(1 claim 18 ,5-cyclooctadiene)iridium(I) claim 18 , (acetylacetonato)dicarbonyliridium(I) claim 18 , bis[1 claim 18 ,2-bis(diphenylphosphino)ethane]carbonyl chloroiridium(I) claim 18 , bis(1 claim 18 ,5-cyclooctadiene)diiridium(I) dichloride claim 18 , bis(1 claim 18 ,5-cyclooctadiene)iridium(I) tetrafluoroborate claim 18 , bis(cyclooctadiene)iridium(I) tetrakis(3 claim 18 ,5-bis(trifluoromethyl)phenyl)borate claim 18 , chlorobis(cyclooctene)iridium(I)dimer claim 18 , (1 claim 18 ,5-cyclooctadiene)bis(methyldiphenylphosphine)iridium(I) hexafluorophosphate claim 18 , (1 claim 18 ,5-cyclooctadiene)(hexafluoroacetylacetonato)iridium(I) claim 18 , (1 claim 18 ,5-cyclooctadiene)-η5-indenyl)iridium(I) claim 18 , (1 claim 18 ,5-cyclooctadiene)(methoxy)iridium(I) dimer claim 18 , (1 claim 18 ,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)-iridium(I) hexafluorophosphate claim 18 , (1 claim 18 ,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)-iridium(I) hexafluorophosphate claim 18 , and (1 claim 18 ,5-cyclooctadiene)(pyridine)(tricyclohexylphosphine)iridium(I) tetrakis[3 claim 18 ,5-bis(trifluoromethyl)phenyl]borate.20. (canceled)21. The method of claim 18 , wherein the chiral ligand is ...

Kinetic resolution of racemic hydroxy ester via asymmetric catalytic hydrogenation and application thereof

The present invention relates to kinetic resolution of racemic δ-hydroxyl ester via asymmetric catalytic hydrogenation and an application thereof. In the presence of chiral spiro pyridyl phosphine ligand Iridium catalyst and base, racemic δ-hydroxyl esters were subjected to asymmetric catalytic hydrogenation to obtain extent optical purity chiral δ-hydroxyl esters and corresponding 1,5-diols. The method is a new, efficient, highly selective, economical, desirably operable and environmentally friendly method suitable for industrial production. An optically active chiral δ-hydroxyl ester and 1,5-diols can be obtained at very high enantioselectivity and yield with relatively low usage of catalyst. The chiral δ-hydroxyl ester and 1,5-diols obtained by using the method can be used as a critical raw material for asymmetric synthesis of chiral drugs (R)-lisofylline and natural drugs (+)-civet, (−)-indolizidine 167B and (−)-coniine. 3. The kinetic resolution method of racemic δ-hydroxyl esters via asymmetric catalytic hydrogenation according to claim 1 , wherein claim 1 , Ris C˜Calkyl claim 1 , phenyl claim 1 , cyclopentyl tert-butyloxyl methyl.4. The kinetic resolution method of racemic -hydroxyl esters via asymmetric catalytic. hydrogenation according to or claim 1 , wherein claim 1 , the said racemic δ-hydroxyl esters also included δ-hydroxyl lactone esters.8. The kinetic resolution method of racemic δ-hydroxyl esters via asymmetric catalytic hydrogenation according to claim 2 , wherein claim 2 , in the presence of organic solvent claim 2 , were added δ-hydroxyl esters claim 2 , catalysts claim 2 , base; the reaction mixture was stirred for 0.5-24 h to react at the hydrogen atmosphere 1-100 atm to obtain optical active chiral δ-hydroxyl esters and corresponding chiral 1 claim 2 ,5-diols.9. The kinetic resolution method of racemic δ-hydroxyl esters via asymmetric catalytic hydrogenation according to - claim 2 , wherein claim 2 , the said base is alcohol alkalis claim 2 , ...

PROCESS FOR PREPARING SUBSTITUTED INDOLE COMPOUNDS

The present invention is directed to a process for preparing Substituted Indole Compounds of Formula (I): wherein R, R, Rand Rare as defined herein. These indole compounds are useful as synthetic intermediates for making inhibitors of HCV NS5A. 2. The process of claim 1 , wherein component (b) of the solution of Step A is an organoiridium complex or a salt thereof.3. The process of claim 2 , wherein the organoiridium complex is selected from fac-Ir(ppy) claim 2 , fac-Ir(dF-ppy) claim 2 , Ir(ppy)(dtbpy) claim 2 , Ir(ppy)and Ir(dF-CF-ppy)(dtbpy) claim 2 , or a salt thereof.4. The process of claim 3 , wherein the organoiridium complex is [Ir(dF-CF-ppy)(dtbpy)](PF).5. The process of claim 1 , wherein component (b) of the solution of Step A is an organoruthenium complex or a salt thereof.6. The process of claim 5 , wherein the organoruthenium complex is selected from [Ru(bpm)]C1 claim 5 , [Ru(bpy)]C1 claim 5 , [Ru(bpz)]C1and [Ru(phen)] Cl.7. The process of claim 1 , wherein component (c) of the solution of Step A is an organic peroxyester.8. The process of claim 7 , wherein the organic peroxyester is tert-butyl peroxybenzoate.9. The process of claim 1 , wherein component (d) of the solution of Step A is selected from acetonitrile claim 1 , N claim 1 ,N-dimethylformamide claim 1 , N claim 1 ,N-dimethylacetamide and dimethylsulfoxide.10. The process of claim 1 , wherein in Step B claim 1 , the UV-visible light has a wavelength of from 350 nm to 500 nm.11. (canceled)12. The process of claim 1 , wherein in Step B claim 1 , the solution is exposed to the UV-visible light for a time period of from 10 minutes to 2 hours.13. The process of claim 12 , wherein in Step B claim 12 , the solution is exposed to the UV-visible light for a time period of from 30 minutes to 1 hour.14. The process of claim 1 , wherein the solution of Step A is maintained at a temperature of from −20° C. to 25° C. throughout the entirety of Step B.15. (canceled)16. The process of claim 1 , wherein for the ...

METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUND, AND NOVEL METAL-DIAMINE COMPLEX

The present invention pertains to a method for producing an optically active compound which includes a step for reducing an imino group of an imine compound or a step for reducing an unsaturated bond of a heterocyclic compound, while in the presence of hydrogen gas as a hydrogen donor and one or more types of complexes selected from a group consisting of a complex represented by general formula (1), a complex represented by general formula (2), a complex represented by general formula (3), and a complex represented by general formula (4) (the general formulas (1)-(4) are as stipulated by claim ). 4. An asymmetric reduction catalyst comprising the complex according to .5. An asymmetric reduction catalyst comprising the complex according to . The present invention relates to a method for selectively producing an optically active compound important as a precursor for synthesis of pharmaceuticals and functional materials, the methods using any of a ruthenium-diamine complex, an iridium-diamine complex, and a rhodium-diamine complex as a catalyst.In the field of production of optically active amines, many asymmetric reactions, including asymmetric reduction, have been developed, and many asymmetric reactions have been reported which use asymmetric metal complexes having optically active phosphine ligands. Meanwhile, for example, there are many documents reporting that complexes in each of which an optically active nitrogen compound is coordinated to a transition metal, such as ruthenium, rhodium, or iridium, have excellent performance as catalysts for asymmetric synthesis reactions (see Chem Rev. (1992), p. 1051, J. Am. Chem. Soc. 117 (1995), p. 7562, J. Am. Chem. Soc. 118 (1996), p. 2521, and J. Am. Chem. Soc. 118 (1996), p. 4916). Especially, synthesis of optically active amines by hydrogenation reaction has been reported recently (see J. Am. Chem. Soc. 133 (2011), p. 9878, and Angew. Chem. Int. Ed 51 (2012), p. 5706).However, the conventional asymmetric synthesis ...

METHODS FOR PRODUCING OXYGEN AND HYDROGEN FROM WATER USING AN IRIDIUM ORGANOMETALLIC CATALYST DEPOSITED ON A TITANIUM DIOXIDE CATALYST

Disclosed is a method for producing oxygen (O) and hydrogen (H) from water, the method comprising (a) obtaining a composition comprising (i) a hybrid catalyst comprising an organo-iridium catalyst deposited on the surface of a titanium dioxide catalyst, and (ii) an aqueous solution having a buffer or having a base wherein the base is present in the aqueous solution in an amount at least 4 times equivalent with respect to the organo-iridium catalyst present on the hybrid catalyst, and (b) exposing the composition to light to produce Oand Hfrom water molecules in the aqueous solution. 1. A method for producing oxygen (O) and hydrogen (H) from water , the method comprising: (i) a hybrid catalyst comprising an organo-iridium catalyst deposited on the surface of a titanium dioxide catalyst; and', '(ii) an aqueous solution having a buffer or having a base wherein the base is present in the aqueous solution in an amount at least 4 times equivalent with respect to the organo-iridium catalyst present on the hybrid catalyst; and, '(a) obtaining a composition comprising{'sub': 2', '2, '(b) exposing the composition to light to produce Oand Hfrom water molecules in the aqueous solution.'}2. The method of claim 1 , wherein the aqueous solution has a base present in the aqueous solution in an amount at 8 times to 20 times equivalent with respect to the organo-iridium catalyst present on the hybrid catalyst.3. The method of claim 1 , wherein the pH of the aqueous solution is 7 to 8.4. The method of claim 1 , wherein the aqueous solution does not include a sacrificial oxidant.5. The method of claim 1 , wherein the aqueous solution further comprises a sacrificial oxidant.6. The method of claim 5 , wherein the sacrificial oxidant is cerium ammonium nitrate (CAN) claim 5 , sodium periodate (NaIO) claim 5 , or sodium persulfate/ruthenium(II)-tris-2 claim 5 ,2′-bipyridine (NaSO/[Ru(bipy)]).7. The method of claim 1 , wherein the hybrid catalyst is heterogeneously dispersed in the aqueous ...

METAL COMPLEXES FOR DEPOSITING FILMS AND METHOD OF MAKING AND USING THE SAME

Provided herein are methods of catalytic hydrosilylation, including triggerable methods, using metal-ligand complexes as catalysts, characterized by formula MLD; wherein: M is a metal; x is equal to the oxidation state of M; each D is independently a neutral coordinating ligand; y is zero or an integer selected from the range of 1 to 4; and each L is independently a mono-anionic ligand. L may be a η,η-β,β-disubstituted-ω-alkenyl ligand. 2. The method of claim 1 , wherein said step of activating initiates a catalytic hydrosilylation reaction between said starting compound and said hydrosilylation reagent; or wherein said step of activating increases the rate of a catalytic hydrosilylation reaction between said starting compound and said hydrosilylation reagent.36-. (canceled)7. The method of claim 1 , wherein said step of activating results in catalytic hydrosilylation characterized by a turnover number greater than or equal to 1000.8. The method of claim 1 , wherein said step of activating is carried out for a time period selected from the range of 1 second to 24 hours.9. (canceled)10. The method of claim 1 , wherein said starting compound claim 1 , said hydrosilylation and said hydrosilylation catalyst are provided in a solution claim 1 , wherein said step of activating comprising providing energy to the solution.1112-. (canceled)13. The method of claim 10 , further comprising stopping the step of providing energy to the solution and/or removing energy from said solution after said hydrosilation of said starting compound.14. The method of claim 1 , wherein said step of activating comprises increasing the temperature of said starting compound and said hydrosilylation reagent in the presence of a hydrosilylation catalyst.1522-. (canceled)23. The method of claim 1 , wherein said hydrosilylation catalyst is formed by conversion of a hydrosilylation precatalyst that comprises said metal-ligand complex to said hydrosilylation catalyst.24. The method of claim 1 , wherein ...

TRANSITION METAL COMPLEXES COMPRISING CARBENE LIGANDS SERVING AS EMITTERS FOR ORGANIC LIGHT-EMITTING DIODES (OLED'S)

Use of transition metal complexes of the formula (I) in organic light-emitting diodes 118-. (canceled)20. The uncharged transition metal complex as claimed in claim 19 , wherein the carbene ligand or ligands is/are monoanionic.21. The uncharged transition metal complex as claimed in claim 19 , wherein the carbene ligand or ligands is/are bidentate.25. The uncharged transition metal complex as claimed in claim 19 , wherein n is 3 and m is 0 claim 19 , and wherein the three carbene ene ligands are identical.26. The uncharged transition metal complex as claimed in claim 27 , wherein the two atoms of the bridge formed by Yand Yare substituted claim 27 , and the substituents of the groups Yand Ytogether form a bridge having a total of four atoms of which one or two may be N-heteroatoms and the remaining atoms are carbon atoms claim 27 , so that the Yand Ytogether with the bridge form a six-membered aromatic ring.27. The uncharged transition claim 19 , metal complex as claimed in claim 19 , wherein Dois N.28. The uncharged transition metal complex as claimed in claim 19 , wherein Dois S or O.29. A process for preparing transition metal complexes as claimed in by the deprotonation of the ligand precursors corresponding to the appropriate carbene ligands and subsequent reaction with suitable metal complexes in which the desired metal is present. The present application is a continuation application of, and claims priority to, U.S. patent application Ser. No. 12/901,610, filed Oct. 11, 2010, now allowed, which is a divisional application of U.S. patent application Ser. No. 10/568,344, now U.S. Pat. No. 7,846,763, which is a 35 U.S.C. §371 national phase application from, and claiming priority to, International Application PCT/EP2004/009269, filed Aug. 18, 2004, which claims priority under 35 U.S.C. §119(a)-(d) to German Application No. 10338550.9, filed Aug. 19, 2003, all of which applications are incorporated herein by reference in their entireties.The present invention ...

METAL COMPLEXES

Metal complexes such as those of formula (I) are contemplated by the present invention. The metal complexes may be used in catalytic reactions as a catalyst. The catalytic reaction may be an autotransfer process, for example hydrogen borrowing. 118.-. (canceled)20. The metal complex of claim 19 , wherein p is 0.22. The metal complex of claim 21 , wherein X is a monoanionic claim 21 , dianionic or trianionic molecule.23. The metal complex of claim 21 , wherein p is 2.24. The metal complex of claim 21 , wherein X is a hydroxide claim 21 , fluoride claim 21 , chloride claim 21 , bromide claim 21 , iodide claim 21 , acetate claim 21 , formate claim 21 , fluorate claim 21 , fluorite claim 21 , bromate claim 21 , bromite claim 21 , iodate claim 21 , iodite claim 21 , chlorate claim 21 , chlorite claim 21 , hydrogen carbonate claim 21 , hypofluorite claim 21 , hypochlorite claim 21 , hypobromite claim 21 , hypoiodite claim 21 , perfluorate claim 21 , perchlorate claim 21 , perbromate claim 21 , periodate claim 21 , chromate claim 21 , cyanate claim 21 , cyanide claim 21 , dihydrogen phosphate claim 21 , dihydrogen phosphite claim 21 , nitrate claim 21 , hydrogen oxalate claim 21 , hydrogen sulfate claim 21 , hydrogen sulfite claim 21 , permanganate claim 21 , nitrite claim 21 , thiocyanate claim 21 , hydride claim 21 , hexafluorophosphate claim 21 , hexafluoroantiminate claim 21 , tetrafluoroborate claim 21 , peroxide claim 21 , [B[3 claim 21 ,5-(CF)CH]] claim 21 , B(CF) claim 21 , Al(OC(CF)). sulfate claim 21 , sulfite claim 21 , sulfide claim 21 , persulfate claim 21 , thiosulfate claim 21 , hyposulfite claim 21 , hydrogen phosphate claim 21 , hydrogen phosphite claim 21 , metasilicate claim 21 , carbonate claim 21 , percarbonate claim 21 , oxalate claim 21 , benzoate claim 21 , tartrate claim 21 , borate claim 21 , boride claim 21 , citrate claim 21 , hypophosphite claim 21 , nitride claim 21 , phosphate claim 21 , phosphide claim 21 , or phosphite.25. The metal complex ...

Method for the synthesis and isolation of facial-tris-homoleptic phenylpyridinato iridium (iii) photocatalysts

Methods of synthesizing and isolating facial-tris-homoleptic phenylpyridinato iridium (III) photocatalysts are disclosed. Also disclosed are methods of recovering excess 2-phenylpyridine ligands from said syntheses.

Hydrogen Bond Directed Photocatalytic Hydrodefluorination and Methods of Use Thereof

Methods of synthesizing compounds comprising fluorinated aryl groups are disclosed, wherein said methods utilize hydrogen bond directed photocatalytic hydrodefluorination.

Metal complexes with heterocycles carbenes

A complex of the formula [LaMbXc]n(A)n I as described in the application useful as homogenous catalysts.

Vapor phase hydroformylation process

Metal complex compounds containing heterocyclic carbenes

Transition metal complexes comprising carbene ligands serving as emitters for organic light-emitting diodes (oled's)

The invention relates to the use of transition metal complexes of formula (I) in organic light-emitting diodes, wherein: M1 represents a metal atom; carbene represents a carbene ligand; L represents a monoanionic or dianionic ligand; K represents a neutral monodentate or bidentate ligand selected from the group consisting of phosphines, CO, pyridines, nitriles and of conjugated dienes that form a π-complex with M1; n represents a number of carbene ligands, whereby n is at least 1; m represents a number of ligands L, whereby m can be 0 or = 1; o represents a number of ligands K, whereby o can be 0 or = 1, and the sum n + m + o depends on the oxidation stage and coordination number of the metal atom used and on the dentation of the ligands carbene, L and K as well as on the charge of the ligands carbene and L, with the condition that n is at least 1. The invention also relates to an OLED containing these transition metal complexes, a light-emitting layer containing these transition metal complexes, OLED's containing this light-emitting layer, devices that contain an inventive OLED, and to special transition metal complexes containing at least two carbene ligands.

Bridged “tethered” metallocenes

The present invention provides a tethered bridged metallocene compound in which the tether typically comprises a segment of the formula —(R 2 ) d —(CH 2 CH 2 ) e (CH═CH) f wherein R 2 is an alkylene or phenylene group, and d, e and f are 1 or 0. One end of the tether reacts with a silane bridged metallocene compound and the other reacts with the support. The activated metallocene compound is capable of producing a polymer having a narrow molecular weight distribution.

TRANSITION METAL COMPLEXES

含镍硅氢加成催化剂及含有该催化剂的组合物

本发明公开了一种组合物，所述组合物含有(A)硅氢加成反应催化剂和(B)脂族不饱和化合物，所述脂族不饱和化合物平均每分子具有一个或多个能够进行硅氢加成反应的脂族不饱和有机基团。所述组合物能够通过硅氢加成反应来反应而形成反应产物，如硅烷、树胶、凝胶、橡胶或树脂。成分(A)含有金属‑配体络合物，所述金属‑配体络合物可以通过包括使金属前体与配体反应的方法来制备。

Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition ' capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Iridium containing hydrosilylation catalysts and compositions containing the catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition ' capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Amino acid complexes and the use thereof in producing olefin polymers

An amino acid complex of the formula I, where M is selected from among Fe, Co, Ni, Pd, Pt and Ir, preferably Ni, can be used for the polymerization of olefins.

Selective, Catalytic, thermal functionalization of secondary or aromatic C-H cyclic hydrocarbon bonds

A process for the catalytic coupling of cyclic hydrocarbons with a functionalizing reagent under thermal conditions to functionalize the cyclic hydrocarbon at its secondary or aromatic C—H site.