NEBULIZER AND CONTAINER

SEAL FOR AN INHALATION DEVICE

ACTIVATION MECHANISM FOR AN AEROSOL DISPENSER

IMPROVED INHALATION DEVICE

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a liquid emission mechanism for an inhalation device, as well as a method of emitting a liquid from an inhalation device. The inhalation device comprises a housing (1), a reservoir (2) for storing a liquid, a pumping unit, said unit comprising a riser pipe (5), a hollow cylindrical part (3) having an interior space and being linearly moveable on the riser pipe (5), wherein the pumping chamber is fluidically connected with the reservoir (2), and a nozzle (6) which is connected liquid-tight to an downstream end portion (5B) of the riser pipe (5), and wherein said linear relative motion can be effected by a relative rotation around a rotational axis (R) of a rotatable part (1A) with respect to a counterpart (1B), such that said relative rotation is converted into said linear relative motion by means of a gear mechanism comprising at least one cam surface having a first section (9A) ...

A DEVICE FOR THE DELIVERY OF A MIST OF A DOSE OF AN OPHTHALMIC LIQUID, AND A PUMP SUITABLE FOR DEVICES FOR THE DELIVERY OF A MIST OF AN OPHTHALMIC LIQUID

The present invention relates to a device for the delivery of a mist of a dose of an ophthalmic liquid, including a housing with a holding chamber having a discharge opening for holding the dose of liquid to be delivered, a pump for pumping, via a dose supply conduit, the dose of the liquid to the holding chamber, the pump being connected with a container containing a plurality of the doses, and an air flow conduit for supplying a flow of air to the holding chamber so as to force the dose delivered by the pump to the holding chamber out through the discharge opening.

PART COUNTER FOR A NEBULISER, NEBULISER WITH SUCH A PART COUNTER, AND SYSTEM WITH SUCH A NEBULISER AND A DOCKING STATION

IMPROVED INHALATION DEVICE

IMPROVED INHALATION DEVICE

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a liquid emission mechanism for an inhalation device, as well as a method of emitting a liquid from an inhalation device. The inhalation device comprises a housing (1), a reservoir (2) for storing a liquid, a pumping unit, said unit comprising a riser pipe (5), a hollow cylindrical part (3) having an interior space and being linearly moveable on the riser pipe (5), wherein the pumping chamber is fluidically connected with the reservoir (2), and a nozzle (6) which is connected liquid-tight to an downstream end portion (5B) of the riser pipe (5), and wherein said linear relative motion can be effected by a relative rotation around a rotational axis (R) of a rotatable part (1A) with respect to a counterpart (1B), such that said relative rotation is converted into said linear relative motion by means of a gear mechanism comprising at least one cam surface having a first section (9A) ...

INHALER

This invention relates to an inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for driving the drive, and with a tensioning part which is configured to both tension the tensioning device and to trigger the pressure generator or discharge of a pharmaceutical agent; and/or wherein further tensioning of the tensioning device requires less force.

A DEVICE FOR THE DELIVERY OF A MIST OF A DOSE OF AN OPHTHALMIC LIQUID, AND A PUMP SUITABLE FOR DEVICES FOR THE DELIVERY OF A MIST OF AN OPHTHALMIC LIQUID

NEBULIZER AND RESERVOIR

Inhaler

An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for the drive, and with a tensioning mechanism for tensioning the tensioning device, whereby the tensioning mechanism has a lever gear for tensioning the tensioning device.

INHALATION DEVICE

NEBULIZER AND CARTRIDGE

BLOCKING DEVICE

The inhalation device for medically active liquids (F) for generation of an aerosol comprises a housing (1), a reservoir (2), a pumping device with a pumping chamber (3), and a nozzle (6), wherein the interior volume of the pumping chamber (3) is changeable by means of linear relative motion of the pumping chamber to the riser pipe (5). Said linear relative motion can be effected by a relative rotation of a rotatable part (1A) which is part of, or connected to, the housing (1) with respect to a second part (1B) of said housing (1), in that said relative rotation can be transferred by means of a gear mechanism into said relative translational motion. A means for the storage of potential energy (7) is provided which is chargeable by means of said relative rotation, and wherein said energy is releasable to said pumping device when released by activation of a release means. A blocking device is provided which is adapted to block activation of the release means and/or release of the means for ...

ATOMIZATION DEVICE AND COUNTER MODULE FOR THE SAME

INHALER

This invention relates to an inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with a pressure generator, which has a tensioning device for driving the drive, and with a tensioning part which is configured to both tension the tensioning device and to trigger the pressure generator or discharge of a pharmaceutical agent; and/or wherein further tensioning of the tensioning device requires less force.

METHODS OF TREATMENT OF VIRAL DISEASES

INHALATION DEVICE SYSTEM

Apparatus and spray applicator

An apparatus (100) for metered dispensing of a liquid from a container (3) and a spray applicator having the apparatus (100). The apparatus (100) comprises a base body (5) and a nozzle body (16) having an outlet nozzle. The nozzle body (16) is mounted so as to be displaceable relative to the base body (5) from a dispensing to a clamping position. The apparatus (100) comprises a reset spring (14) for moving the nozzle body (16) from the clamping to the dispensing position. The nozzle body (16) and the valve body form a burst chamber (19). By pressure on the trigger mechanism (26), the locking of the valve body (10) is triggered and the spray burst spring (7) presses the valve body (10) in the nozzle direction. A non-return valve is arranged upstream in the valve body. The spray burst chamber is connected to the outlet nozzle.

TENSIONING ARRANGEMENT FOR AEROSOL DISPENSER AND AEROSOL DISPENSER

METHODS OF TREATMENT USING NICLOSAMIDE

FLUID DELIVERY APPARATUS

Locking mechanism for an aerosol dispenser

A locking mechanism for an aerosol dispenser is presented having a first body structure, a second body structure rotatably attached to the first body structure, a spindle rotatably attached to the second body structure, the spindle having an actuator rotationally cooperating with the first body structure such that rotation of the first body structure relative to the second body structure causes rotation of the actuator and of the spindle, a movable element arranged around the spindle, the spindle being rotatable relative to the movable element, wherein rotation of the spindle causes movement of the movable element along the spindle from an initial position to a final position, and a locking element, wherein in the final position the movable element applies a radial force onto the locking element causing the locking element to bend in the radial direction thereby preventing rotation between the first body structure and the second body structure.

SPRAYER AND STORAGE DEVICE

A sprayer, comprising a shell (1), an atomization module (2), a rotating module (4) rotatably mounted on the shell (1), a linking module (5) mounted on the rotating module (4), and a locking module (7). The linking module (5) is configured by a container bottle (200), and a starting module (3) can be pressed, so that liquid in the container bottle (200) undergoes an atomization operation outside the sprayer (100) by means of the atomization module (2). The locking module (7) is connected to the bottom of the container bottle (200). When the sprayer (100) completes a preset number of atomization operations, a locking mechanism (73) is limited by moving towards the shell (1), so as to lock the operation of the sprayer (100). A storage device comprises the container bottle (200) and the locking module (7). The locking module (7) comprises a box body (71) and a trigger mechanism (72). The box body (71) is formed with an opening (711). The trigger mechanism (72) comprises a revolving member ...

Inhaler

An inhaler, preferably for insertion into a nostril, in particular a horse's nostril, with an inhalation valve, which has a movable valve element, whereby the valve element is designed in an annular manner and has an outer edge and an inner edge, whereby the valve element is fastened at the outer edge, the inner edge forms the boundary of an indentation of the valve element, and the inhalation valve has a valve body seat that corresponds to the inner edge.

SYSTEM, CARTRIDGE AND METHOD

SPRAYER AND STORAGE DEVICE

A nebulizer and a storage device are provided. The nebulizer includes a casing, an atomization module fixed to the casing, a rotating module rotatably assembled to the casing, a linking module assembled to the rotating module, and a locking module. The linking module is configured to be connected to a bottom of the container bottle, and the starting module is configured to drive the nebulizer by being pushed, thereby enabling liquid in the container bottle to be atomized toward an outside of the nebulizer through the atomization module in an atomization process. The locking module is configured to be connected to a bottom of the container bottle. When the nebulizer completes a predetermined number of times of the atomization process, the locking mechanism is moved toward the casing and is then limited to restrict an operation of the nebulizer. Accordingly, after the nebulizer completes the predetermined number of times of the atomization process, the locking module can restrict rotation ...

Medicinal Device with Container

The invention relates to a hand-held medicinal device, particularly a nebuliser, for delivering a liquid medicament preparation from a container having a container cap. The medicament preparation may be based for example on an alcoholic solvent or may contain a similar substance with an increased vapour pressure. The proposed nebuliser with the installed container comprises a sealing system made up of two seals at the junction between the device and container, which prevent loss of liquid, diffusion leaks and exchange of gases with the environment at this point.

Nozzle and inhaler and method for producing a nozzle

A nozzle, an inhaler with a nozzle and a method for producing a nozzle are proposed. The nozzle comprises two holes formed in a flat plate. Then, the plate is deformed such that the axes of the holes intersect so that jets of fluids generated by the holes impinge with each other.

Nebulizer

A nebulizer and a housing part for a nebulizer are proposed, wherein a container containing the fluid to be nebulized is provided. The container is moveable back and forth for conveying and nebulization of the fluid. A securing device forms a transportation lock for holding the container unmovable in a delivery state with closed transportation lock. A control part opens the transportation lock by means of at least one rib or arm when the control part is moved towards the securing device. The securing device comprises a ring-like holding part with inwardly extending holding elements for holding the container inseparably.

Liquid dispensing system

A manually energized dispensing system for dispensing a fluid ( 8 ) contained in a non-pressurized container ( 7 ). The dispensing system comprises a dispensing head ( 1 ) comprising a housing ( 2 ), a nozzle through which fluid to be dispensed exits, a pump ( 4 ) mounted in the housing, and a pump actuation mechanism ( 3 ), the pump comprising a rotor ( 13 ) rotatably and axially displaceable with respect to a stator ( 12 ). The pump rotor comprises first and second axial extensions ( 17, 18 ) of different diameters, mounted in corresponding chambers ( 15, 16 ) of the stator, first and second seals ( 19, 20 ) mounted in the stator housing and sealingly surrounding the first and second axial rotor extensions, the rotor extensions comprising liquid supply channels ( 22, 24 ) that, in conjunction with the sealing rings, operate as valves that open and close communication between an inlet of the pump connected to the inside of the container ( 7 ) and the pump chambers, respectively the pump chambers and an outlet of the pump connected to the dispensing head nozzle, as a function of the angular displacement of the pump rotor. The rotor is coupled mechanically to the actuation mechanism ( 3 ) and the actuation mechanism is configured to be manually operated to release or to drive the pump rotor to dispense fluid, respectively to block the pump rotor to stop dispensing fluid.

Nebulizer and container

A nebulizer as well as a container with a fluid for such a nebulizer are proposed. The container comprises a control device which indicates initially an unused state of the container before first use. An indicator device stops via a locking device further use of the container in a locked state when a predetermined number of uses has been reached or exceeded. After replacement of the container, the nebulizer can be reset and used again.

Seal for an inhalation device

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an improved seal construction for an inhalation device having a nebulizing nozzle and a piston which moves relative to a pumping chamber in order to generate pumping pressure and to an inhalation device comprising such seal. An inhalation device for medically active liquids (F) for generation of an aerosol comprises a housing ( 1 ), an impingement-type nozzle ( 6 ) for generating the nebulised aerosol by collision of at least two liquid jets, the nozzle ( 6 ) being firmly affixed to the user-facing side of the housing ( 1 ) such as to be immobile relative to the housing ( 1 ), inside the housing ( 1 ) the inhalation device comprises a reservoir ( 2 ) for storing a liquid (F), a pumping device with a pumping chamber ( 3 ) for generation of a pressure inside said pumping chamber ( 3 ), wherein the pumping chamber ( 3 ) is fluidically connected with the reservoir ( 2 ), a riser pipe ( 5 ) which can be received with at least one reservoir-facing, interior end ( 5 A) in said pumping chamber ( 3 ), and said nozzle ( 6 ) which is connected liquid-tight to an exterior end ( 5 B) of the riser pipe ( 5 ), wherein the interior volume of the pumping chamber ( 3 ) is changeable by means of relative motion of the pumping chamber to the riser pipe ( 5 ) or vice versa. A gap ( 10 ) can be present between an outside of said riser pipe ( 5 ) and an inside of said pumping chamber ( 3 ), and a seal ( 9 ) bridging said gap ( 10 ) in order to minimize pressure loss when a pressure is generated inside said pumping chamber ( 3 ). Said seal ( 9 ) can be fixed to said outside of said riser pipe ( 5 ), and be moveable with respect to said inside of said pumping chamber ( 3 ).

Inhalation device with a pumping unit

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to an inhalation device for delivering a nebulised medically active aerosol for inhalation therapy comprising a pumping unit, said pumping unit comprising a riser pipe (2), a hollow cylindrical part (3) having an interior space configured to receive an upstream end portion (21) of said riser pipe (2), said cylindrical part (3) being moveable on the riser pipe (2), wherein the cylindrical part and the riser pipe form a pumping chamber having a variable volume, wherein a gap (4) is present between a lateral outside surface (22) of the upstream end portion (21) of said riser pipe (2) and a lateral internal surface (31) of said cylindrical part (3), wherein a seal (1) is present between the outside surface (22) of said riser pipe (2) and the internal surface (31) of said cylindrical part (3), thus physically bridging said gap (4), and wherein the seal (1) has a cap-like shape configured to fit around the upstream end portion (21) of the riser pipe (2), having at least one opening (11) for providing a fluid connection between an interior space of said riser pipe (2) and said pumping chamber, and wherein at an interior surface (14) of the seal (1), at least one interior protrusion (16) is present which is configured to be received by at least one respective recess (23) of the riser pipe (2).

Methods of treatment using niclosamide

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.

Atomising devices and methods

A metered dose inhaler comprises a piston (3) which is mounted in a cavity (2) within a body (1), and is urged by a pre-loaded spring (6) into a reduced cross-section pressure chamber (4). The piston (3) may be loaded by means of an actuating rod (31) having a handle (32), and may be latched in a loaded position by a latching means (33). A liquid drug (e.g. in aqueous solution) is contained in a collapsible bag (10). Metered quantities of the drug are successively presented in the pressure chamber (4), and then subjected to a sudden and great increase in pressure, to eject the liquid drug through an atomising head (22), to reduce it to a fine atomised spray of small mean particle size - for example, less than 30 micrometres. Non-return valves (13 and 23) control the flow of liquid through the device. The sudden pressure pulse is caused by releasing the spring loaded piston (3), upon depressing an actuating button (35) connected to the latching means (33).

液体分配系统

一种用于分配容纳在非加压式容器(7)中的流体(8)的手动促动的分配系统。该分配系统包括具有壳体(2)的分配头(1)、待分配的流体通过其而离开的喷嘴、安装在壳体内的泵(4)以及泵促动机构(3)，所述泵包括能相对于定子(12)旋转和轴向移动的转子(13)。泵转子包括具有不同直径的安装在定子的相应腔室(15,16)中的第一和第二轴向延伸部(17,18)，安装在定子壳体中且密封式围绕着第一和第二轴向转子延伸部的第一和第二密封件(19,20)，所述转子延伸部包括液体供给通道(22,24)，它们与密封环相结合而作为阀来操作，所述阀能根据泵转子的角位移来打开和关闭处于与容器(7)的内部和相应泵室相连的泵入口和与分配头喷嘴相连的泵出口之间的连通。转子机械式地连接到促动机构(3)，该促动机构构造为能手动地操作，以释放或驱动泵转子而分配流体，或者阻止泵转子而停止分配流体。

흡입기

본 발명은 구동을 위한 인장 디바이스를 가지는 압력 발생기와, 인장 디바이스를 인장시키기 위한 인장 메커니즘을 가지는, 바람직하게 콧구멍, 특히 말의 콧구멍 내로 삽입하기 위한 흡입기에 관한 것이며, 인장 메커니즘은 인장 디바이스를 인장시키기 위한 레버 기어를 가진다.

Nozzle and inhaler and method of nozzle fabrication

FIELD: process engineering. SUBSTANCE: invention relates to proportioned (distributed) dispensing of inhalation of drugs by nozzle or inhaler, preferably, proportioning inhaler not exploiting compressed gas. Inhaler for dispensing inhalation drug in the form of aerosol incorporates nozzle 12 is made from primordially flat plate 22. Two holes 21 in plate 22 feature round cross-section and hydraulic diameter of 5 to 15 mcm and are produced by laser boring, axes 23 of holes 21 being perpendicular to plate 22. After making the holes 21, plate 22 is deformed by deep drawing so that axes 23 of holes 21 cross at outlet side 24 of nozzle 12. EFFECT: perfected design, lower costs. 7 cl, 5 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 495 726 (13) C2 (51) МПК B05B 1/14 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2010133906/05, 16.01.2009 (24) Дата начала отсчета срока действия патента: 16.01.2009 (73) Патентообладатель(и): БЕРИНГЕР ИНГЕЛЬХАЙМ ФАРМА ГМБХ УНД КО. КГ (DE) R U Приоритет(ы): (30) Конвенционный приоритет: 16.01.2008 GB 0800709.8 30.01.2008 GB 0801619.8 (72) Автор(ы): ДАНН Стивен Т. (GB) (43) Дата публикации заявки: 27.02.2012 Бюл. № 6 2 4 9 5 7 2 6 (45) Опубликовано: 20.10.2013 Бюл. № 29 2 4 9 5 7 2 6 R U (85) Дата начала рассмотрения заявки PCT на национальной фазе: 16.08.2010 C 2 C 2 (56) Список документов, цитированных в отчете о поиске: JP 11076871 А, 23.03.1999. US 2003/075623 A1, 24.04.2003. JP 1024696 A, 14.09.1998. WO 94/00686 A, 06.01.1994. RU 2154536 C2, 20.08.2000. RU 2258567 C1, 20.08.2005. RU 2775759 A1, 23.05.1981. (86) Заявка PCT: EP 2009/000252 (16.01.2009) (87) Публикация заявки РСТ: WO 2009/090084 (23.07.2009) Адрес для переписки: 105082, Москва, Спартаковский пер., 2, стр. 1, секция 1, эт. 3, "ЕВРОМАРКПАТ" (54) НАСАДКА И ИНГАЛЯТОР И СПОСОБ ИЗГОТОВЛЕНИЯ НАСАДКИ (57) Реферат: Изобретение относится к дозированной (распределенной) выдаче препарата для ингаляции посредством насадки или ...

喷嘴、吸入器以及生产喷嘴的方法

提出了喷嘴(12)、具有喷嘴(12)的吸入器(图1)和生产喷嘴的方法。喷嘴包括形成在平板(22)中的两个孔(21)。然后，板(21)被形变使得各孔的轴线交叉，从而通过孔产生的流体喷射流相互碰撞。

Metered dose aspirator

雾化器

提出了一种流体的雾化器(1)，尤其用于医学气雾剂治疗。为了允许更简便的操作并且给予改善了的操作可靠性，提供雾化器时，在所述雾化器内已经布置了保持所述流体的密封的容器(3)，并且构造所述雾化器使得在雾化器首次使用之前或使用期间在雾化器内部打开所述容器。作为替代或添加，构造所述雾化器使得所述容器不可以被替换并且尤其不可以被去除。

Inhaler

본 발명은 구동을 위한 인장 디바이스를 가지는 압력 발생기와, 인장 디바이스를 인장시키기 위한 인장 메커니즘을 가지는, 바람직하게 콧구멍, 특히 말의 콧구멍 내로 삽입하기 위한 흡입기에 관한 것이며, 인장 메커니즘은 인장 디바이스를 인장시키기 위한 레버 기어를 가진다. The present invention relates to a pressure generator having a tensioning device for actuation and an inhaler having a tensioning mechanism for tensioning the tensioning device, preferably for insertion into the nostrils, in particular the nostrils of a horse, the tensioning mechanism comprising: It has a lever gear for tensioning.

Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same

A dry powder inhalator for delivering a precise dose of a medicament contains a mesh disc impregnated with a series of spaced, medicament doses about the disc periphery. The inhalator is armed by manually retracting a finger pull extending downwardly from the bottom of the inhalator housing or rotating the bottom of the housing. The user inserts a mouthpiece on the housing into the mouth and inhales. This causes a chamber in the housing under a diaphragm to evacuate, thereby pulling the diaphragm down onto a knock out lever. The pivoting of the lever enables release of a piston into a cylinder which first compresses, and then dispenses a reduced volume of air at high pressure in a burst up through the medicament disc. When the burst of air hits the impregnated disc, the dose is forced out of the mesh's interstices, producing a cloud of the drug in its powdered form, which is inhaled by the user.

Atomiser comprising a counter and an end of operation lock

Atomizer provided with a monitoring device for counting actuations of the atomizer

Part counter for a nebuliser, nebuliser and system with a nebuliser and a docking station

Es wird ein Zerstäuber zur Erzeugung eines einatembaren Aerosols vorgeschlagen, wobei der Zerstäuber einen Teilzähler zum Ermitteln eines Teils von Benutzungen des Zerstäubers aufweist. Des Weiteren werden ein System mit einem Zerstäuber und einer Dockingstation sowie ein Verfahren zum Zählen von Benutzungen eines Zerstäubers vorgeschlagen. There is proposed an atomizer for producing an inhalable aerosol, the atomizer comprising a fractional counter for determining a portion of uses of the atomizer. Furthermore, a system with a nebulizer and a docking station and a method for counting uses of a nebulizer are proposed.

Nebulizer

A nebulizer for a fluid is proposed, particularly for medicinal aerosol therapy. To allow easy operation, the nebulizer has a valve device, so that air supply openings in a mouthpiece can be blocked off.

Breath actuated nasal pump

A breath actuated nasal drug delivery device includes a housing having a spray port; a reservoir housing a liquidous medicament; and a selectively actuable pump. A breath actuated triggering mechanism includes a mouthpiece and a diaphragm. A pressure differential across the diaphragm causes an elastically deformable drive element (e.g., spring) to release stored potential energy, causing the pump's plunger to move to thereby pump the medicament to the spray port. A cocking lever can be pivotally mounted to the housing for causing the drive element to store potential energy. The triggering mechanism can include a cam element pivotally attached to the housing and the diaphragm that rotates in response to movement of the diaphragm. A follower element can be pivotally connected to the plunger for movement therewith; the follower element releasably engages the cam element. Related methods are also described.

Method for coating a surface of a component

Adapter, inhalation device and nebulizer

Medical device comprising a container

The invention relates to a hand-held device (1), in particular an atomizer, for discharging a liquid pharmaceutical preparation from a container (3) having a container cap (31). The pharmaceutical preparation can, for example, be based on an alcoholic solvent or contain a similar substance having an increased vapor pressure. The proposed atomizer having an inserted container comprises a sealing system composed of two seals at the connecting site between the device and the container, which prevent loss of liquid, diffusion leaks and gas exchange with the surroundings at this site.

Nebulizer

A nebulizer is proposed which comprises a replaceable container containing fluid, a housing part detachable from the nebulizer for replacing the container, and an operation counter inseparable from the housing part as depicted in exemplary FIG. 10 . The operation counter comprises a lead screw and an associated rider both supported by the housing part.

Nebulizer

A nebulizer (1) comprises a replaceable container (3) with fluid (2) to be nebulized. The container comprises an inseparable indicator device (25). The container and the indicator device are axially moved during nebulization and tensioning of the nebulizer. The indicator device controls locking of the nebulizer against further use if a predetermined number of uses has been reached or exceeded.

Locking mechanism for spring-actuated device

一种弹簧-启动的输出驱动装置，用于小型化高压生成装置的药物气雾剂治疗中，以便雾化小剂量的液体药物。这种输出驱动装置的锁定加力机构是用相当小的力加力，并用一支手放松，而且在长期使用中非常可靠。锁定加力机构包括使弹簧加力的升力传动装置，例如一种螺旋推进传动装置；带接合锁定表面的环形布置的锁定元件；用于限定弹簧运行的两个支座；以及放松按钮。该装置结构紧凑，制造经济，易于组装，而且其中的零件损耗率小。即使该装置包含大的弹簧力，对于非专业人员也能可靠和容易地进行操作。因此，雾化的药物可以高精确度的进行计量。

INHALATION DEVICE AND METHOD OF ITS USE

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2019 131 176 A (51) МПК A61M 11/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2019131176, 30.04.2018 (71) Заявитель(и): СОФТХЕЙЛ НВ (BE) Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): БАРТЕЛС, Франк (DE), РАВЕРТ, Юрген (DE) 28.04.2017 EP 17168869.0; 28.04.2017 US 62/491,965 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 28.11.2019 EP 2018/061056 (30.04.2018) (87) Публикация заявки PCT: WO 2018/197730 (01.11.2018) R U (54) ИНГАЛЯЦИОННОЕ УСТРОЙСТВО И СПОСОБ ЕГО ИСПОЛЬЗОВАНИЯ (57) Формула изобретения 1. Портативное ингаляционное устройство для подачи распыляемого аэрозоля медицинского назначения для ингаляционной терапии, содержащее (a) корпус (1), имеющий обращенную к пользователю сторону; (b) сопло (6) ударного типа для образования распыляемого аэрозоля посредством столкновения по меньшей мере двух потоков жидкости, причем сопло (6) является жестко прикрепленным к обращенной к пользователю стороне корпуса (1) таким образом, что оно является неподвижным относительно корпуса (1); (c) резервуар (2) для текучей среды, размещенный внутри корпуса (1); и (d) нагнетательный блок, размещенный внутри корпуса (1), причем нагнетательный блок имеет - расположенный выше по ходу текучей среды конец, который сообщается посредством текучей среды с резервуаром (2) для текучей среды; - расположенный ниже по ходу текучей среды конец, который сообщается посредством текучей среды с соплом (6); причем нагнетательный блок выполнен с возможностью нагнетания текучей среды (F) из резервуара (2) для текучей среды в сопло (6); причем нагнетательный блок также содержит (i) подающую трубку (5), имеющую расположенный выше по ходу текучей среды конец, причем подающая трубка (5) Стр.: 1 A 2 0 1 9 1 3 1 1 7 6 A Адрес для переписки: 190000, Санкт-Петербург, БОКС-1125 2 0 1 9 1 3 1 1 7 6 (86) Заявка PCT: R U (43) Дата публикации заявки: 28.05.2021 Бюл. № 16 A 2 0 1 9 1 3 1 ...

Improved inhalation device

本发明涉及用于液体的吸入装置的领域。特别地，本发明涉及一种用于吸入装置的液体排放机构、以及一种从吸入装置排放液体的方法。吸入装置包括壳体(1)、用于储存液体的储器(2)、泵送单元，该单元包括立管(5)、具有内部空间且能够在立管(5)上线性移动的中空圆柱形部分(3)，其中泵室与储器(2)和喷嘴(6)流体连接，喷嘴液密连接到立管(5)的下游端部(5B)，并且其中所述线性相对运动可通过可旋转部分(1A)相对于配对部分(1B)围绕旋转轴(R)的相对旋转来实现，使得所述相对旋转通过齿轮机构转换成所述线性相对运动，所述齿轮机构包括至少一个具有第一区段(9A)和第二区段(9B)的凸轮表面，并且其中设有势能储存器件(7)。该装置的特征在于所述凸轮表面具有在第一区段和第二区段(9A、9B)之间的高度恒定的第三区段(9C)，使得当所述配对部分(1B)沿着所述第三区段(9C)滑动时，不会发生线性相对运动。一种用于产生气溶胶的方法包括，在可旋转部分(1A)旋转时，用于用液体填充泵室的第一装填阶段、和用于从喷嘴(6)排放经雾化液体的第二排出阶段，并且其特征在于在所述两个阶段之间，存在第三静止阶段，在第三静止阶段期间，尽管发生进一步旋转，泵室的体积仍保持恒定。

Dispenser

Dispenser

Atomising devices and method

Apparatus for dosed dispensing of metered quantities of liquid in the form of drop flare under pressure

FIELD: medicine, in particular, inhalers. SUBSTANCE: dosing inhaler has piston 3 mounted within cavity 2 of casing 1 and is loaded with preliminarily loaded spring 6 in pressure chamber of reduced section 4. Piston 3 may be loaded by drive stem 31 with handle 32 and may be locked in loaded position by locking device 33. Liquid medical drug is contained within tearable enclosure 10. Metered quantities of drug are supplied in succession into pressure chamber 4 and subjected to the action of abruptly increased pressure to force liquid preparation through dispersion nozzle 22 and reduce particle average size of finely dispersed liquid flare to less than 30 micron. Return valves 13 and 23 regulate flow rate through this apparatus. Instant pressure pulse is created due to release of spring-loaded piston 3 upon depression of control button 35 connected with locking device 33. EFFECT: increased efficiency, simplified construction and enhanced reliability in operation. 18 cl, 8 dwg ЗУОТОГС ПЧ ГЭ РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (19) ВИ” 2104 048 ' 13) СЛ М А 61 М 114/00 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 505323514, 21.03.1991 (30) Приоритет: 21.03.1990 СВ 9006340.5 01.11.1990 СВ 9023767.8 (46) Дата публикации: 10.02.1998 (56) Ссылки: Ц5, патент, 4391620, кл. С 03 В 4002, 1983. (86) Заявка РСТ: СВ 91/00433 (21.03.91) (71) Заявитель: Борингер Ингельгейм Интернациональ ГмбХ (ОЕ) (72) Изобретатель: Теренс Эдвард Вестон[ СВ], Стефан Теренс Данне[СВ] (73) Патентообладатель: Борингер Ингельгейм Интернациональ ГмбХ (ОЕ) (54) УСТРОЙСТВО ДЛЯ ДОЗИРОВАННОЙ ВЫДАЧИ ОТМЕРЕННОГО КОЛИЧЕСТВА ЖИДКОСТИ В ВИДЕ КАПЕЛЬНОГО РАСПЫЛА ПОД ДАВЛЕНИЕМ (57) Реферат: Использование: изобретение относится к медицине и может быть использовано в ингаляторах. Сущность изобретения: дозирующий ингалятор содержит поршень (3), который установлен в полости (2) внутри корпуса (1) и поджат предварительно нагруженной пружиной (6) в напорной камере уменьшенного ...

Atomizer and method for atomizing fluid

An atomizer (1) and a method of dispensing and atomizing fluid (2) into individual containers through a nozzle (12) are proposed. To improve the dosing accuracy, a preliminary amount of fluid (2), flushing the nozzle (12), is dispensed before each dose is dispensed.

Patent RU2019131176A3

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2019 131 176 A (51) МПК A61M 11/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2019131176, 30.04.2018 (71) Заявитель(и): СОФТХЕЙЛ НВ (BE) Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): БАРТЕЛС, Франк (DE), РАВЕРТ, Юрген (DE) 28.04.2017 EP 17168869.0; 28.04.2017 US 62/491,965 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 28.11.2019 EP 2018/061056 (30.04.2018) (87) Публикация заявки PCT: WO 2018/197730 (01.11.2018) R U (54) ИНГАЛЯЦИОННОЕ УСТРОЙСТВО И СПОСОБ ЕГО ИСПОЛЬЗОВАНИЯ (57) Формула изобретения 1. Портативное ингаляционное устройство для подачи распыляемого аэрозоля медицинского назначения для ингаляционной терапии, содержащее (a) корпус (1), имеющий обращенную к пользователю сторону; (b) сопло (6) ударного типа для образования распыляемого аэрозоля посредством столкновения по меньшей мере двух потоков жидкости, причем сопло (6) является жестко прикрепленным к обращенной к пользователю стороне корпуса (1) таким образом, что оно является неподвижным относительно корпуса (1); (c) резервуар (2) для текучей среды, размещенный внутри корпуса (1); и (d) нагнетательный блок, размещенный внутри корпуса (1), причем нагнетательный блок имеет - расположенный выше по ходу текучей среды конец, который сообщается посредством текучей среды с резервуаром (2) для текучей среды; - расположенный ниже по ходу текучей среды конец, который сообщается посредством текучей среды с соплом (6); причем нагнетательный блок выполнен с возможностью нагнетания текучей среды (F) из резервуара (2) для текучей среды в сопло (6); причем нагнетательный блок также содержит (i) подающую трубку (5), имеющую расположенный выше по ходу текучей среды конец, причем подающая трубка (5) Стр.: 1 A 2 0 1 9 1 3 1 1 7 6 A Адрес для переписки: 190000, Санкт-Петербург, БОКС-1125 2 0 1 9 1 3 1 1 7 6 (86) Заявка PCT: R U (43) Дата публикации заявки: 28.05.2021 Бюл. № 16 A 2 0 1 9 1 3 1 ...

Adapter, inhalation device, and atomizer

An inhalation device includes: a chamber for intermediate storage of an aerosol, a first connection for a nebuliser that produces the aerosol, a second connection on a patient side for delivering the aerosol, and a third connection for breathable air, where the chamber is fluidically connected in a valve-free manner on an inlet side to the first connection when the nebuliser is attached, and the chamber is connected to the third connection in parallel on the inlet side via an inlet valve so that the breathable air from the third connection flows into the chamber.

Method for coating a surface of a component

The invention relates to a method for coating a surface ( 44 ), in particular a microstructured surface, of a component ( 55 ) comprising different materials, in particular glass and silicon, wherein the surface ( 44 ) is first activated and then coated, wherein an oxidising solution, a basic solution or an acid-oxidising solution is used to activate the surface ( 44 ).

Atomizer for distributing liquids for medical purposes

The invention relates to an atomizer for distributing liquids from at least one cartridge inserted in the atomizer and to a cartridge and to a system comprising an atomizer and a cartridge inserted therein. Atomizers (1) of the aforementioned kind are for example required for the application of inhalable liquid pharmaceutical formulations and comprise, as the essential structural components, a cartridge holder (4), arranged in the housing (3), a mouthpiece (5) configured on the housing (4), in which an atomizer device (6) is located, and a connecting pipe system (7) which interlinks the atomizer device (6) and the cartridge holder (4). The atomizer device (6) comprises at least one nozzle base (8) and the connecting pipe system (7) comprises at least one channel (9) with a tubular piston (10) slidably guided therein, whereby said tubular piston (10) comprises a valve base (21). According to a first embodiment, the atomizer (1) is provided with a first tubular piston (10a), slidably guided in a first channel (9a), and a second tubular piston (10b), slidably guided in a second channel (9b), and the first tubular piston (10a) and the second tubular piston (10b) extend into the cartridge holder (4).

atomizer

Es wird ein Zerstäuber mit einem einsetzbaren Behälter und einer Überwachungseinrichtung zur Zählung von Betätigungen des Zerstäubers vorgeschlagen. Die Überwachungseinrichtung ist in einem lösbaren Gehäuseteil angeordnet und erfaßt unmittelbar Bewegungen des Behälters während eines Zerstäubungsvorgangs, einen Zuluftstrom im Bereich eines Mundstücks und/oder die Erzeugung von Aerosol, um dies als tatsächlichen Austrag von Fluid zu detektieren und die Betätigung des Zerstäubers zu zählen, wobei vorzugsweise zusätzlich der jeweilige Zeitpunkt der Betätigung des Zerstäubers erfaßt und gespeichert wird. So werden eine verbesserte Überwachung und Benutzerführung ermöglicht. It is proposed an atomizer with a usable container and a monitoring device for counting operations of the atomizer. The monitoring device is arranged in a detachable housing part and detects directly movements of the container during an atomization process, a supply air flow in the region of a mouthpiece and / or the generation of aerosol to detect this as the actual discharge of fluid and to count the operation of the atomizer preferably in addition the respective time of actuation of the atomizer is detected and stored. This allows for improved monitoring and user guidance.

Atomizer

【課題】流体に高圧を発生させるための装置を含むアトマイザを、設計が簡単で、製造が安価であり、その機能に適するようにする。 【解決手段】本発明のアトマイザは、シリンダ（１）内で移動できるピストン（２）と高圧室（４）と弁部材（３）を含む弁とを備え、弁部材（３）は中空ピストンで案内され補助的な力なしで軸線方向に移動でき、弁部材の軸線方向移動を制限する第１止め手段（８）が中空ピストンに設けられ、密封面が弁部材の入口端部に設けられ、弁部材が第１止め手段に当接すると弁は開き弁部材が密封面と当接すると弁は閉じ、中空ピストンが出口端領域外側に第１止め手段を有し、弁部材は中空ピストンの出口端部で軸線方向に移動できるよう取付けられ、弁部材は複数のフック（６，１０）を有し、密封面が弁部材の入口端部に設けられる装置を備えることを特徴とする。 【選択図】図１a

Device for producing high pressure in dispersed fluid medium

FIELD: hydraulic engineering. SUBSTANCE: device contains hollow plunger mounted for movement inside cylinder and valve member mounted for axial movement with respect to the hollow plunger and guided by the hollow plunger. The valve member is placed close to the plunger end inside or in front of it. The device is used in mechanical atomizer of high pressure. The atomizer has a housing consisting of two parts. The housing receives pump housing with a nozzle, locking gear, spring housing with a spring, depressed tank for storing the fluid, and mechanical counter built into the spring housing. The valve operates without any additional force, rapidly shut down in response to fluid flow, and strongly isolates from high pressure. The atomizer is safe, convenient in operation and ecological compatibility. The fluid flow rate is measured very accurate. The valve operates under the friction on the walls of the cylinder. Device also has space of high pressure placed inside the cylinder in front of the plunger, stopper- rod device placed in the hollow plunger which stops valve member motion. The valve member is sealed at its inlet. EFFECT: enhanced efficiency. 26 cl, 18 dwg соб с ПЧ с» (19) РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ ВИ `” 2 179 075 (51) МПК” (13) С2 (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ В 05 В 11/00, А 47 К 5/12, А 61 М 15/00 (21), (22) Заявка: 98108402/12, 04.10.1996 (24) Дата начала действия патента: 04.10.1996 (30) Приоритет: 04.10.1995 ОЕ 195 36 902.5 (43) Дата публикации заявки: 10.04.2000 (46) Дата публикации: 10.02.2002 (56) Ссылки: ЕК 2699390 А, 24.06.1994. 0$ 2497944 А, 12.03.1996. СВ 2243880 А, 13.11.1991. 9$ 54172143 А, 05.12.1995. $4 1797848 А, 28.02.1993. (85) Дата перевода заявки РСТ на национальную фазу: 05.05.1998 (86) Заявка РСТ: ЕР 96/04351 (04.10.1996) (87) Публикация РСТ: М/О 97/12687 (10.04.1997) (98) Адрес для переписки: 103064, Москва, ул. Казакова, 16, НИИР-Канцелярия "Патентные поверенные Квашнин, ...

Medical device with container

Pump-activated mechanism for prolonged spraying of aerosol

FIELD: spraying.SUBSTANCE: power unit for obtaining a prolonged release of product from container comprises container cover, made with possibility of attachment to open end of said container, cylindrical barrel configured to be mounted on said container cover, a piston housing reciprocating in said cylindrical barrel, piston retained by said piston housing with possibility of back-and-forth movement together with it, wherein the piston is located in the cylindrical barrel with the possibility of sliding sealing interaction and together with the cylindrical shell defines the pump chamber. Also comprises rotary lead screw extending into said piston housing, drive sleeve, made with possibility of rotation, engagement means located between said drive sleeve and said lead screw, wherein engagement means have an engagement position for turning the lead screw when the drive sleeve is rotated and a disengagement position to enable rotation of the lead screw, which does not lead to rotation of the drive sleeve, first means engaged between the lead screw and the piston housing, and second means engaged between the piston housing and the cylindrical barrel to reciprocate the piston housing and piston in first direction for suction of product into pump chamber when drive bushing and lead screw rotate, power accumulation device configured to accumulate energy when piston housing moves in said first direction, wherein energy storage device displaces piston housing and piston in second direction opposite to first direction for product compression in pump chamber, normally closed valve in fluid communication with pump chamber to control product flow from pump chamber, and a reciprocating drive acting on said valve for its opening and providing product release from pump chamber when said drive is pressed.EFFECT: power assembly can be used with various energy storage devices such as springs, gases or elastics to exert pressure on product to be dispensed when the actuator is turned.27 ...

Patent RU2015141962A3

7 ВУ’” 2015141962” АЗ Дата публикации: 27.03.2019 Форма № 18 ИЗПМ-2011 Федеральная служба по интеллектуальной собственности Федеральное государственное бюджетное учреждение 5 «Федеральный институт промышленной собственности» (ФИПС) ОТЧЕТ О ПОИСКЕ 1. . ИДЕНТИФИКАЦИЯ ЗАЯВКИ Регистрационный номер Дата подачи 2015141962/12(064785) 05.04.2012 Приоритет установлен по дате: [ ] подачи заявки [ ] поступления дополнительных материалов от к ранее поданной заявке № [Х] приоритета 02.10.2014 по первоначальной заявке № 2014139943 из которой данная заявка выделена [ ] подачи первоначальной заявки № из которой данная заявка выделена [ ] подачи ранее поданной заявки № [Х] подачи первой(ых) заявки(ок) в государстве-участнике Парижской конвенции (31) Номер первой(ых) заявки(ок) (32) Дата подачи первой(ых) заявки(ок) (33) Код страны 1. 13/439,519 04.04.2012 05 Название изобретения (полезной модели): [Х] - как заявлено; [ ] - уточненное (см. Примечания) АКТИВИРУЕМЫЙ ОДНИМ ПОВОРОТОМ МЕХАНИЗМ НАСОСА ДЛЯ ПРОДОЛЖИТЕЛЬНОГО РАСПЫЛЕНИЯ АЭРОЗОЛЯ Заявитель: АЛЬТЕРНАТИВ ПЭКЕДЖИН СОЛЮШЕНС, ЛЛС, 0$ 2. ЕДИНСТВО ИЗОБРЕТЕНИЯ [Х] соблюдено [ ] не соблюдено. Пояснения: см. Примечания 3. ФОРМУЛА ИЗОБРЕТЕНИЯ: [Х] приняты во внимание все пункты см. п см. Примечания [ ] приняты во внимание следующие пункты: р [ | принята во внимание измененная формула изобретения (см. Примечания) 4. КЛАССИФИКАЦИЯ ОБЪЕКТА ИЗОБРЕТЕНИЯ (ПОЛЕЗНОЙ МОДЕЛИ) (Указываются индексы МПК и индикатор текущей версии) ВО5В 11/02 (2006.01) 5. ОБЛАСТЬ ПОИСКА 5.1 Проверенный минимум документации РСТ (указывается индексами МПК) ВОВ 11/02, ВОВ 11/00 5.2 Другая проверенная документация в той мере, в какой она включена в поисковые подборки: 5.3 Электронные базы данных, использованные при поиске (название базы, и если, возможно, поисковые термины): Езрасепеё Рабеагсв, КОРТО, ОРТО 6. ДОКУМЕНТЫ, ОТНОСЯЩИЕСЯ К ПРЕДМЕТУ ПОИСКА Кате- Наименование документа с указанием (где необходимо) частей, Относится к гория* относящихся к предмету поиска пункту ...

Medicinal device with container

The invention relates to a hand-held medicinal device, particularly a nebulizer, for delivering a liquid medicament preparation from a container having a container cap. The medicament preparation may be based for example on an alcoholic solvent or may contain a similar substance with an increased vapor pressure. The proposed nebulizer with the installed container comprises a sealing system made up of two seals at the junction between the device and container, which prevent loss of liquid, diffusion leaks and exchange of gases with the environment at this point.

Nebulizer with axially movable and lockable container and indicator

A nebulizer includes a replaceable container with fluid to be nebulized. The container includes an inseparable indicator device. The container and the indicator device are axially moved during nebulization and tensioning of the nebulizer. The indicator device controls locking of the nebulizer against further use if a predetermined number of uses has been reached or exceeded.

Device of miniaturised construction for producing high pressure in a fluid to be atomised

A miniaturised device for producing high pressure in a fluid imposes stringent requirements on the manufacturing process. The device according to the invention consists of a hollow piston (57) displaceably mounted in a cylinder and a valve member (58) which is guided by the hollow piston (57) and mounted so as to be axially movable relative to the hollow piston (57). The valve member (58) is arranged at one end of the hollow piston (57) inside or immediately in front of the end of the hollow piston (57). The device is used in a mechanically operated high pressure atomiser. This consists of a two-part housing which comprises a pump housing (52) with nozzle (54), a blocking mechanism (62), a spring housing (67) with spring (68), a non-pressurised storage container (71) for the fluid (72) and a mechanical counter integrated in the spring housing (67). The valve (58) operates without any auxiliary force, closes very rapidly and is sealed tight against high pressure. The atomiser is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately. The atomiser is used, for example, to produce an inhalable aerosol of a liquid medicament without the use of a propellant gas, at 320 bar, for example.

Pressure-increasing device for fluid to be atomised, dispenser and puming device with alternating movement

A találmány tárgya nyomásnövelő eszköz, célszerűen miniatürizáltkivitelben, amelynek áramlási útvonalat biztosító furattal (7)kialakított, hengerben (1) mozgatható hengeres, üreges dugattyúja(17), valamint szelepe van. A találmány lényege, hogy a hengeres,üreges dugattyú (17) bemeneti vagy kimeneti végén kamra (20) vagybelépési vég van kialakítva, amelynek belső átmérője nagyobb, mint azüreges dugattyú (17) más részének belső átmérője, és az üregesdugattyúnak (17) befelé hajló, peremezett vége (19) van, a hengeren(1) belül, a dugattyú (17) előtt nagynyomású kamra (4) van kialakítva,a szelep bemeneti végén tömítőfelülettel rendelkező szelepzáró elem(18) van, a szelepzáró elem az üreges dugattyú (17) nagyobb belsőátmérőjű részébe van tengelyirányban mozgathatóan beszerelve, aszelepzáró elem (18) legnagyobb átmérője kisebb, mint az üregesdugattyú (17) kamrájának (20) vagy belépési végének a belső átmérője,és nagyobb, mint az üreges dugattyú (17) fennmaradó részének belsőátmérője; az üreges dugattyú (17) kamrájának (20) vagy belépésivégének a kimeneti végén a szelepzáró elem (18) üreges dugattyún belültartására peremezett vég (19) vagy eltolható test van kialakítva, és aszelep zárva van, amikor a szelepzáró elem (18) érintkezik az üregesdugattyú (17) kamrájának (20) vagy belépési végének kimeneti végén aperemezett véggel (19) vagy az eltolható testtel. A találmány tárgyatovábbá a nyomásnövelő eszközt tartalmazó porlasztókészülék és anyomásnövelő eszközt tartal- mazó, váltakozó mozgású pumpálókészülékis. ŕ SUMMARY OF THE INVENTION The present invention relates to a pressure-increasing device, preferably in a miniaturized version, having a cylindrical hollow piston (17) movable in the cylinder (1) and a valve. It is an object of the present invention that the inlet or outlet end of the cylindrical hollow piston (17) is provided with a chamber (20) or inlet end having an internal diameter greater than the inner diameter of the other part of the cavity (17) and inwardly ...

Miniaturized device for producing high pressure in a fluid to be atomized

Device of miniaturised construction for producing high pressure in a fluid to be atomised

Device of miniaturised construction for producing high pressure in a fluid to be atomised

A reciprocating pump device for pressurizing fluid, comprising: a cylinder (1); a hollow cylindrical piston (2) having a piston axis reciprocable in said cylinder, said piston providing a path for fluid to flow therethrough, wherein a portion of said piston defines a valve seat; a pressure chamber (4) disposed in said cylinder, wherein fluid flows through said piston into said pressure chamber; a valve member (3) movable by said piston between a closed position in contact with said valve member comprising a surface that engages said valve seat, wherein said valve member is configured so that it cannot rotate about an axis transverse to the piston axis. 990 י" ב בסיון התשס" ד - June 1, 2004

Device for high pressure fluid

Device of miniaturised construction for producing high pressure in a fluid to be atomised

MINIATURIZED DEVICE FOR PRODUCING HIGH PRESSURE IN FLUIDS TO BE SPRAYED

Device of miniaturised construction for producing high pressure in a fluid to be atomised

Minituarised design for producing high pressure fluids to be sprayed

A miniaturised device for producing high pressure in a fluid imposes stringent requirements on the manufacturing process. The device according to the invention consists of a hollow piston (57) displaceably mounted in a cylinder and a valve member (58) which is guided by the hollow piston (57) and mounted so as to be axially movable relative to the hollow piston (57) The valve member (58) is arranged at one end of the hollow piston (57) inside or immediately in front of the end of the hollow piston (57). The device is used in a mechanically operated high pressure atomiser. This consists of a two-part housing which comprises a pump housing (52) with nozzle (54), a blocking mechanism (62), a spring housing (67) with spring (68), a non-pressurised storage container (71) for the fluid (72) and a mechanical counter integrated in the spring housing (67). The valve (58) operates without any auxiliary force, closes very rapidly and is scaled tight against high pressure. The atomiser is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately. The atomiser is used, for example, to produce an inhalable aerosol of a liquid medicament without the use of a propellant gas, at 320 bar, for example. a

Device of miniaturised construction for producing high pressure in a fluid to be atomised

A miniaturised device for producing high pressure in a fluid imposes stringe nt requirements on the manufacturing process. The device according to the invention consists of a hollow piston (57) displaceably mounted in a cylinder and a valve membe r (58) which is guided by the hollow piston (57) and mounted so as to be axially movable relative to the hollow piston (57). The valve member (58) is arranged at one end of the hollow piston (57) inside or immediately in front of the end of the hollow piston (57). Th e device is used in a mechanically operated high pressure atomiser. This consists of a t wo- part housing which comprises a pump housing (52) with nozzle (54), a blocking mechanism (62), a spring housing (67) with spring (68), a non-pressurised storage container (71) for the fluid (72) and a mechanical counter integrated in the spring housing (67). The valve (58) operates without any auxiliary force, closes very rapidly and is sealed tight against high pressure. The atomiser is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately. The atomiser is used, for example, to produce an inhalable aeros ol of a liquid medicament without the use of a propellant gas, at 320 bar, for example.</SD OAB>

Miniaturized construction device to produce high pressure in a fluid to be atomized

Miniature device for generating high pressure in a fluid for atomization

Apparatus of miniaturised construction for generating hight pressure of a fluid to be atomised

A miniaturised device for producing high pressure in a fluid imposes stringent requirements on the manufacturing process. The device according to the invention consists of a hollow piston (57) displaceably mounted in a cylinder and a valve member (58) which is guided by the hollow piston (57) and mounted so as to be axially movable relative to the hollow piston (57). The valve member (58) is arranged at one end of the hollow piston (57) inside or immediately in front of the end of the hollow piston (57). The device is used in a mechanically operated high pressure atomiser. This consists of a two-part housing which comprises a pump housing (52) with nozzle (54), a blocking mechanism (62), a spring housing (67) with spring (68), a non-pressurised storage container (71) for the fluid (72) and a mechanical counter integrated in the spring housing (67). The valve (58) operates without any auxiliary force, closes very rapidly and is sealed tight against high pressure. The atomiser is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately. The atomiser is used, for example, to produce an inhalable aerosol of a liquid medicament without the use of a propellant gas, at 320 bar, for example.

Fluid sprayer, containing miniaturized fluid compression device

A miniaturised device for producing high pressure in a fluid imposes stringent requirements on the manufacturing process. The device according to the invention consists of a hollow piston (57) displaceably mounted in a cylinder and a valve member (58) which is guided by the hollow piston (57) and mounted so as to be axially movable relative to the hollow piston (57). The valve member (58) is arranged at one end of the hollow piston (57) inside or immediately in front of the end of the hollow piston (57). The device is used in a mechanically operated high pressure atomiser. This consists of a two-part housing which comprises a pump housing (52) with nozzle (54), a blocking mechanism (62), a spring housing (67) with spring (68), a non-pressurised storage container (71) for the fluid (72) and a mechanical counter integrated in the spring housing (67). The valve (58) operates without any auxiliary force, closes very rapidly and is sealed tight against high pressure. The atomiser is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately. The atomiser is used, for example, to produce an inhalable aerosol of a liquid medicament without the use of a propellant gas, at 320 bar, for example.

Device of a miniaturized structure for exercising high pressure in fluid so that it will not be pulvaerized

The minituarized device has strict requirements to the process of manufacture. The device contains a hollow piston (57) mounted with a facility of shiting to a cylinder, and valve (58) which is guided by piston (57) and mounted in such a way as to be axially mobile towards it. Valve (58) is fitted at one of the ends of piston (57), inside or immediately before its end. The device is used in a mechanically high pressure controlled atomizer. The atomizer is safe, has simplified control, is not injurious to the environment and the fluid can be measured with high accuracy. It is designed, for example, for the manufacture of aerosol of a liquid medicament for inhalation without using driving gas at 320 bar. It consists of a casing made of two parts which house a casing of a pump (52) with a nozzle (54), interlocking mechanism (62) cavity for a spring (67) with a spring (68), also containing a non-pessurized container (71) for the fluid (72) and a mechanical counter built in cavity (67) of the spring. Valve (58) operates without any axial force and closes very quickly closely blocking the high pressure. 39 claims, 4 figures

Arrangement of miniaturized structure for producing high pressure in a fluid to be atomized

En miniatyrisert anordning for å frembringe høyt trykk i et fluid stiller stren-ge krav til fremstillingsprosessen. Anordningen i henhold til oppfinnelsen består av et hult stempel (57) som er forskyvbart anordnet i en sylinder, samt et ventil-legeme (58) som føres av det hule stempel (57) og er montert slik at det er aksialt bevegelig i forhold til stempelet (57). Ventillegemet (58) er anordnet ved en ende av det hule stempel (57) inne i og umiddelbart foran enden av stempelet (57). Anordningen anvendes i en mekanisk drevet høytrykksforstøver. Denne utgjøres av et to-delt hus som omfatter enpumpehylse (52) med et munnstykke (54), en blokkeringsmekanisme (62), et fjærhus (67) med fjær (68), en ikke-trykksatt for-. i rådsbeholder (71) for fluidet (72), samt en mekanisk teller integrert i fjærhuset (67). Ventilen (58) fungerer uten noen hjelpekraft, lukkes meget raskt og avtetter godt mot høyt trykk. Forstøveren er sikker og lett å bruke samt miljøvennlig. Fluidet doseres meget nøyaktig. Forstøveren anvendes f.eks. for å frembringe et inhalerbart aerosol av et flytende medikament uten bruk av drivgass, f.eks. ved 320 bar.

Device of miniaturised construction for producing high pressure in a fluid to be atomised

Miniaturized fluid pressure setting device, fluid atomizer atomizer and a reciprocating pump device for producing high pressure in a fluid

En miniatyrisert anordning for å frembringe høyt trykk i et fluid stiller strenge krav til fremstillingsprosessen. Anordningen i henhold til oppfinnelsen består av et hult stempel (57) som er forskyvbart anordnet i en sylinder, samt et ventillegeme (58) som føres av det hule stempel (57) og er montert slik at det er aksialt bevegelig i forhold til stempelet (57). Ventillegemet (58) er anordnet ved en ende av det hule stempel (57) inne i og umiddelbart foran enden av stempelet (57). Anordningen anvendes i en mekanisk drevet høytrykksforstøver. Denne utgjøres av et to-delt hus som omfatter en pumpehylse (52) med et munnstykke (54), en blokkeringsmekanisme (62), et fjærhus (67) med fjær (68), en ikke-trykksatt forrådsbeholder (71) for fluidet (72), samt en mekanisk teller integrert i fjærhuset (67). Ventilen (58) fungerer uten noen hjelpekraft, lukkes meget raskt og avtetter godt mot høyt trykk. Forstøveren er sikker og lett å bruke samt miljøvennlig. Fluidet doseres meget nøyaktig. Forstøveren anvendes f.eks. for å frembringe et inhalerbart aerosol av et flytende medikament uten bruk av drivgass, f.eks. ved 320 bar. ?? ?? ?? ?? 1

Miniature fluid pressure generating device

A miniaturised device for producing high pressure in a fluid imposes stringent requirements on the manufacturing process. The device according to the invention consists of a hollow piston (57) displaceably mounted in a cylinder and a valve member (58) which is guided by the hollow piston (57) and mounted so as to be axially movable relative to the hollow piston (57). The valve member (58) is arranged at one end of the hollow piston (57) inside or immediately in front of the end of the hollow piston (57). The device is used in a mechanically operated high pressure atomiser. This consists of a two-part housing which comprises a pump housing (52) with nozzle (54), a blocking mechanism (62), a spring housing (67) with spring (68), a non-pressurised storage container (71) for the fluid (72) and a mechanical counter integrated in the spring housing (67). The valve (58) operates without any auxiliary force, closes very rapidly and is sealed tight against high pressure. The atomiser is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately. The atomiser is used, for example, to produce an inhalable aerosol of a liquid medicament without the use of a propellant gas, at 320 bar, for example.

Device of miniaturised construction for producing high pressure in a fluid to be atomised

Device of miniaturized construction for producing high pressure in a fluid to be atomised

유체에 고압을 발생하기 위한 본 발명의 소형화된 장치는 제조 방법의 요구에 잘 맞는 것이다. 본 발명에 따른 장치는 실린더에 부착가능하게 장착된 중공 피스톤(57)과, 상기 중공 피스톤(57)에 대하여 축방향으로 이동가능할 수 있도록 장착되고 중공 피스톤(57)에 의하여 안내되는 밸브 부재(58)를 포함한다. 상기 밸브 부재(58)는 중공 피스톤(57)의 단부의 내부 또는 바로 전방에서 중공 피스톤(57)의 일단부에 정렬된다. 상기 장치는 기계적으로 작동되는 고압 분무기에 사용된다. 이것은 노즐(54)을 가지는 펌프 하우징(52)과, 블로킹 매카니즘(62)과, 스프링(58)을 가지는 스프링 하우징(67)과, 유체(72)용의 비압력 저장 용기(71) 및, 상기 스프링 하우징(57)에 일체로된 기계적인 카운터를 포함하는 2부분의 하우징으로 구성된다. 상기 밸브(58)는 어떠한 보조 힘이 없이 작동하고, 매우 빠르게 폐쇄하며, 고압에 대하여 견고하게 밀봉된다. 상기 분무기는 안전하고, 작동하기에 간단하며, 환경 친화적이다. 상기 유체는 매우 정확하게 계량된다. 상기 분무기는 예를 들면, 320 bar에서 추진 가스를 사용하지 않고 액체 약제의 흡입가능한 에어러졸을 발생시키는데 사용된다. The miniaturized device of the present invention for generating high pressure in a fluid is well suited to the needs of the manufacturing method. The device according to the invention comprises a hollow piston 57 attachably mounted to a cylinder and a valve member 58 mounted movably axially with respect to the hollow piston 57 and guided by the hollow piston 57. ). The valve member 58 is aligned at one end of the hollow piston 57 at or just in front of the end of the hollow piston 57. The device is used in a mechanically operated high pressure sprayer. This includes a pump housing 52 having a nozzle 54, a blocking mechanism 62, a spring housing 67 having a spring 58, a non-pressure reservoir 71 for the fluid 72, and It consists of a two part housing including a mechanical counter integral to the spring housing 57. The valve 58 operates without any auxiliary force, closes very quickly, and is tightly sealed against high pressure. The nebulizer is safe, simple to operate, and environmentally friendly. The fluid is metered very accurately. The nebulizer is used to generate an inhalable aerosol of the liquid medicament without using propellant gas, for example, at 320 bar.

Device of miniaturized construction for producing high pressure in a fluid, atomizer for spraying pressurized liquid and reciprocating pump device for producing high pressure in a fluid

In the present invention, there is disclosed a device of miniaturized construction for producing high pressure in a fluid said device comprising a cylindrical hollow piston (17, 22, 28, 31) displaceable mounted in a cylinder (1) having performed in its interior a route (7) for fluid (72), and a high-pressure chamber (4) disposed inside the cylinder (1) upstream the piston (17, 22, 28, 31). Said hollow cylindrical piston (17, 22, 28, 31) has an enlarged portion (20, 33) at its inlet or outlet end the inside diameter of which is greater than inside diameter in the remainder of the hollow piston (17, 22, 28, 31), and the hollow piston (17, 22, 28, 31) also has an inwardly shaped edge (19, 24) for making an edge either all over the periphery thereof or on a portion of its periphery in the inlet or outlet end. The device further comprises a valve closing due to resistance acting against direction of fluid (72) flow on a valve element (18, 23, 29, 37) or due to friction on the cylindrical wall, and the valve element (18, 23, 29, 37) with a predetermined sealing surface at the inlet end thereof. Said valve element (18, 23, 29, 37) is guided and mounted axially movable inside the hollow piston (17, 22, 28, 31) in the enlarged portion (20, 33) thereof and maximum diameter of the valve element (18, 23, 29, 37) is smaller than inside diameter of the hollow piston (17, 22, 28, 31) in the enlarged portion (20, 33) thereof and greater than inside diameter in the remainder of the hollow piston (17, 22, 28, 31). At the outlet end of the hollow piston (17, 22, 28, 31) enlarged portion (20, 33), there are performed driving means for retaining the valve element (18, 23, 29, 37) inside the hollow piston (17, 22, 28, 31). The valve is closed when the valve element (18, 23, 29, 37) fits on to said predetermined sealing surface, and is open when the valve element (18, 23, 29, 37) fits on to the driving means at the outlet and of the hollow piston (17, 22, 28, 31) enlarged portion (20, 33 ...

MINIATURIZED CONSTRUCTION DEVICE TO PRODUCE HIGH PRESSURE IN A FLUID TO BE ATOMIZED.

SE DESCRIBE UN DISPOSITIVO EN MINIATURA PARA PRODUCIR ALTAS PRESIONES EN UN FLUIDO QUE IMPONE ALTOS REQUISITOS DE CALIBRACION EN EL PROCEDIMIENTO DE FABRICACION. EL DISPOSITIVO SEGUN LA INVENCION CONSTA DE UN PISTON (57) HUECO MONTADO DE FORMA DESPLAZABLE EN UN CILINDRO Y UN MIEMBRO DE VALVULA (58) QUE ESTA GUIADO POR EL PISTON HUECO (57) Y MONTADO PARA DESPLAZARSE AXIALMENTE CON RELACION AL PISTON HUECO (57). EL MIEMBRO DE VALVULA (58) ESTA DISPUESTO EN UN EXTREMO DEL PISTON HUECO (57) DENTRO O INMEDIATAMENTE ENFRENTE DEL EXTREMO DEL PISTON HUECO (57). EL DISPOSITIVO SE UTILIZA EN UN ATOMIZADOR DE ALTA PRESION OPERADO MECANICAMENTE. EL ANTERIOR CONSTA DE UNA CARCASA EN DOS PIEZAS QUE COMPRENDE UNA CARCASA (52) DE LA BOMBA CON UNA BOQUILLA (54), UN MECANISMO (62) DE BLOQUEO, UNA CARCASA (67) DEL MUELLE (68), UN RECIPIENTE (71) DE ALMACENAMIENTO NO PRESURIZADO PARA EL FLUIDO (72) Y UN CONTADOR MECANICO INTEGRADO EN EL ALOJAMIENTO (67) DEL MUELLE. LA VALVULA (58) OPERA SIN NINGUNA FUERZA AUXILIAR, SE CIERRA MUY RAPIDAMENTE Y ESTA SELLADA A MODO ESTANCO CONTRA LAS ALTAS PRESIONES. EL ATOMIZADOR ES SIMPLE Y SEGURO DE OPERAR Y MEDIOAMBIENTALMENTE ACEPTABLE. EL FLUIDO SE MIDE CON MUCHA EXACTITUD. EL ATOMIZADOR SE USA, POR EJEMPLO, PARA PRODUCIR UN AEROSOL INHALABLE DE UN MEDICAMENTO LIQUIDO, SIN EL USO DE GAS PROPULSOR, POR EJEMPLO A 320 BARES.

Miniature high pressure generating device for fluid

Device for producing high pressure in a fluid in miniature.

A MINIATURISED DEVICE FOR PRODUCING HIGH PRESSURE IN A FLUID IMPOSES STRINGENT REQUIREMENTS ON THE MANUFACTURING PROCESS. THE DEVICE ACCORDING TO THE INVENTION CONSISTS OF A HOLLOW PISTON (2) DISPLACABLY MOUNTED IN A CYLINDER (1) AND A VALVE MEMBER (3) WHICH IS GUIDED BY THE HOLLOW PISTON (2) AND MOUNTED SO AS TO BE AXIALLY MOVABLE RELATIVE TO THE HOLLOW PISTON (2). THE VALVE MEMBER (3) IS ARRANGED AT ONE END OF THE HOLLOW PISTON (2) INSIDE OR IMMEDIATELY IN FRONT OF THE END OF THE HOLLOW PISTON (2). THE DEVICE IS USED IN A MECHANICALLY OPERATED HIGH PRESSURE ATOMISER. THIS CONSISTS OF A TWO PART HOUSING WHICH COMPRISES A PUMP HOUSING (52) WITH NOZZLE (54), A BLOCKING MECHANISM (62), A SPRING HOUSING (67) WITH SPRING (68), A NON-PRESSURISED STORAGE CONTAINER (71) FOR THE FLUID AND A MECHANICAL COUNTER INTEGRATED IN THE SPRING HOUSING (67). THE VALVE OPERATES WITHOUT ANY AUXILIARY FORCE, CLOSES VERY RAPIDLY AND IS SEALED TIGHT AGAINST HIGH PRESSURE. THE ATOMISER IS SAFE AND SIMPLE TO OPERATE AND ENVIRONMENTALLY FRIENDLY. THE FLUID IS METERED EXTREMELY ACCURATELY. THE ATOMISER IS USED, FOR EXAMPLE, TO PRODUCE AN INHALABLE AEROSOL OF A LIQUID MEDICAMENT WITHOUT THE USE OF PROPELLANT GAS, AT 320 BAR, FOR EXAMPLE.FIG. 6A

DEVICE FOR THE GENERATION OF HIGH PRESSURE IN A MINIATURE FLUID, SPRAYER WITH SUCH DEVICE AND ITS USE

QUE COMPRENDE: A) UN PISTON HUECO QUE ES DESPLAZABLE EN UN CILINDRO; B) UN RECINTO DE ALTA PRESION QUE SE HALLA DELANTE DEL PISTON Y DENTRO DEL CILINDRO; Y C) UNA VALVULA CARACTERIZADA POR: I) UN PISTON HUECO CILINDRICO CON UN TOPE EN EL LADO DE SALIDA DEL PISTON; II) UN CUERPO DE VALVULA GUIADO INMEDIATAMENTE JUNTO AL EXTREMO DE SALIDA DEL PISTON Y DESPLAZANDOSE AXIALMENTE; Y C) UN TOPE EN EL PISTON HUECO, QUE MANTIENE JUNTO EL CUERPO DE VALVULA CON EL PISTON Y UNA SUPERFICIE DE OBTURACION. EL PULVERIZADOR DE ALTA PRESION CONSTA DE UNA ENVUELTA DE DOS PIEZAS, QUE A LA VEZ CONTIENE UNA ENVUELTA DE BOMBA CON TOBERA, UN MECANISMO DE TENSADO CON BLOQUEO, UNA ENVUELTA DEL RESORTE CON RESORTE, UN DEPOSITO DE ALMACENAMIENTO SIN PRESION PARA EL FLUIDO Y UN CONTADOR MECANICO INTEGRADO EN LA ENVUELTA DEL RESORTE. SE UTILIZA PARA LA GENERACION EXENTA DE GAS PROPULSOR DE UN AEROSOL INHALABLE A PARTIR DE MEDICAMENTO LIQUIDO WHAT IT INCLUDES: A) A HOLLOW PISTON THAT IS MOVABLE IN A CYLINDER; B) A HIGH PRESSURE ENCLOSURE WHICH IS IN FRONT OF THE PISTON AND WITHIN THE CYLINDER; AND C) A VALVE CHARACTERIZED BY: I) A CYLINDRICAL HOLLOW PISTON WITH A STOP ON THE OUTLET SIDE OF THE PISTON; II) AN IMMEDIATELY GUIDED VALVE BODY NEXT TO THE PISTON OUTLET END AND MOVING AXIALLY; AND C) A STOP ON THE HOLLOW PISTON, WHICH KEEPS THE VALVE BODY TOGETHER WITH THE PISTON AND A SEALING SURFACE. THE HIGH PRESSURE SPRAYER CONSISTS OF A TWO PIECE CASING, WHICH AT THE SAME TIME CONTAINS A PUMP CASING WITH NOZZLE, A SPRING MECHANISM WITH LOCKING, A SPRING WRAPPING WITH SPRING, A STORAGE TANK WITHOUT PRESSURE FOR FLUID AND A MECHANICAL METER INTEGRATED IN THE SPRING WRAP. IT IS USED FOR THE GENERATION FREE OF PROPELLER GAS FROM AN INHALABLE AEROSOL FROM LIQUID MEDICATION

Device of miniaturised construction for producing high pressure in a fluid to be atomised

Small device for creating pressure in the fluid to be sprayed.

Isbu bulus, bir akiskan içinde yüksek basinç olusturma islevini yerine getiren minyatür hale getirilmis bir cihaz ile ilgilidir. Bulusa göre cihaz,bir silindir içine yer degistirebilir sekilde bir oyuk piston (57) ve oyuk piston (57) tarafindan yönlendirilen ve oyuk piston (57)'ye nazaran eksensel olarak hareket edebilecek sekilde monte edilmis bir supap elemani (58)'den meydana gelir. Subap elemani (58), oyuk piston (57)'nin bir ucunda, oyuk piston (57)'nin içinde ya da ucunun hemen karsisinda yerlestirilmistir. Cihaz, mekanik olarak çalisan bir yüksek basinçli atomizör içinde kullanilir. This invention relates to a miniaturized device that performs the function of generating high pressure in a fluid. According to the invention, the device consists of a valve member (58) which is displaceable in a cylinder and guided by a hollow piston (57) and axially movable relative to the hollow piston (57). . The valve member 58 is located at one end of the hollow piston 57, inside the hollow piston 57 or just opposite the tip. The device is used in a mechanically operated high pressure atomizer.

Device for producing high pressure in a fluid in miniature

DEVICE FOR THE GENERATION OF HIGH PRESSURE IN A FLUID IN MINIATURE REALIZATION, SPRAYER WITH SUCH DEVICE AND ITS USE

La invención se refiere a un dispositivo para la generación de alta presión en un fluido en realización miniatura, que consta de un pistón, que es desplazable en un cilindro, un recinto de alta presión, que se halla delante del pistón dentro del cilindro, y una válvula, caracterizado por - un pistón hueco cilíndrico, - un cuerpo de válvula, que está guiado por el pistón hueco y está dispuesto desplazable axialmente respecto al pistón hueco, - un tope en la zona del lado de salida del cuerpo de válvula, que mantiene junto el cuerpo de válvula con el pistón hueco, y - una superficie de obturación definida en el lado de entrada del cuerpo de válvula. The invention relates to a device for the generation of high pressure in a fluid in miniature embodiment, consisting of a piston, which is movable in a cylinder, a high-pressure chamber, which is in front of the piston inside the cylinder, and a valve, characterized by - a cylindrical hollow piston, - a valve body, which is guided by the hollow piston and is axially displaceable relative to the hollow piston, - a stop in the region of the outlet side of the valve body, which it holds together the valve body with the hollow piston, and - a defined sealing surface on the inlet side of the valve body.

Device of miniaturised construction for producing high pressure in a fluid and atomizer comprising that device

Uredaj minijaturizovane konstrukcije za stvaranje visokog pritiska u fluidu, naznacen time, sto ovaj uredaj kao prvo sadrzi cilindricni suplji klip (17, 22, 28, 31) koji je pomerljiv u cilindru (1) za strujanje fluida kroz njega, pri cemu cilindricni suplji klip (17, 22, 28, 31) ima prosireni deo (20, 33) na svom ulaznom ili izlaznom kraju ciji unutrasnji precnik je veci od unutrasnjeg precnika ostalog dela supljeg klipa (17, 22, 28, 31), a osim toga ulazni kraj ili izlazni kraj supljeg klipa (17, 22, 28, 31) ima i prema unutra povijenu ivicu (19, 24), zatim kao drugo komoru (4) visokog pritiska koja se nalazi u cilindru (1) ispred supljeg klipa (17, 22, 28, 31) i kao trece ventil koji se aktivira bez dejstva pomocne sile koju stvara opruga i koji ima ventilsko telo (18, 23, 29, 37) sa definisanom zaptivnom povrsinom na svom ulaznom kraju, koje ventilsko telo (18, 23, 29, 37) je vodeno u supljem klipu (17, 22, 28, 31) u njegovom prosirenom delu (20, 33) u kome je postavljeno aksijalno pomerljivo, pri cemu je maksimalni precnik ventilskog tela (18, 23, 29, 37) manji od unutrasnjeg precnika supljeg klipa (17, 22, 28, 31) na njegovom prosirenom delu (20, 33), a veci je od unutrasnjeg precnika ostalog dela supljeg klipa (17, 22, 28, 31), dok je na izlaznom kraju prosirenog dela (20, 33) supljeg klipa (17, 22, 28, 31) predviden granicnik u vidu povijene ivice (19, 24), odnosno potisnog tela (32) za drzanje ventilskog tela (18, 23, 29, 37) unutar supljeg klipa (17, 22, 28, 31), tako da je ventil zatvoren kada ventilsko telo (18, 23, 29, 37) naleze na definisanu zaptivnu povrsinu na ulaznom kraju ventilskog tela (18, 23, 29, 37), odnosno ventil je otvoren kada ventilsko telo (18, 23, 29, 37) naleze na granicnik u vidu povijene ivice (19, 24), odnosno potisnog tela (32) na izlaznom kraju prosirenog dela (20, 33) supljeg klipa (17, 22, 28, 31).

Device for producing high pressure in a fluid in miniature form.

Locking mechanism for a spring-actuated device

A spring-actuated output drive device is used for example in medical aerosol therapy for a miniaturised high-pressure producing device for atomising a small dose of a liquid medicament. A locking-stressing-mechanism for such an output d rive device is to be stressed with the application of a relatively small amount of force and is to be released with one hand and is to operate reliably over a prolonged period of time. The locking-stressing-mechanism comprises a force step-up transmission, for example a screw thrust transmission for stressing the spring, an annularly arranged locking member with engaging locking surfaces, two abutments for limiting the travel of the spring and a release button. It is compact, economical to produce, easy to assemble and comprises components with a low rate of wear. It can be reliably and easily handled by unskilled persons, even when high spring forces are involved. A medicament to be atomised can thus be metered with a very high degree of accuracy.

Nebulizer for applying liquids on the cornea

The invention relates to a nebulizer for applying liquids on the cornea or the ocular connective tissue, comprising special eye adapters for said nebulizer. The invention also relates to the use of nebulizers in ophthalmological applications. The inventive nebulizers are propellant-free and have an energy accumulator for supplying the energy needed for the nebulization process.

Locking-tensioning mechanism for a miniaturised high-pressure atomiser

The invention relates to a locking-tensioning mechanism for a miniaturised high-pressure generator, the construction of said mechanism being configured only for the volume of liquid that is to be delivered. The volume that is to be delivered by said high-pressure generator can be retroactively modified by adjusting the stop of the elastic part. The basic components of the locking-tensioning mechanism and the high-pressure generator remain unchanged. At least one additional component is provided as a spacer in the form of intermediate rings, stepped pulleys, adjusting screws or adjusting nuts. A continuous helical-sliding gear or a helical-sliding gear that can be adjusted in steps can also be used to adjust a stop of the elastic part. The volume to be delivered can be modified either discontinuously or continuously during the assembly of the locking-tensioning mechanism, or prior to the use of the high-pressure generator, or during the use of said high-pressure generator. The locking-tensioning mechanism for a miniaturised high-pressure generator with a reproducibly adjustable volume, lying in the microlitre range, of liquid to be delivered can be used, for example, in a high-pressure atomiser for producing an aerosol that can be inhaled, or in a needle-free injector for injecting a volume of liquid into animal or vegetable tissue.

Manually actuated atomiser

The manual sputterer for fluids, to apply a droplet spray to a surface, has energy stored by a spring (59) using a coil spring, a plate spring or a gas spring. together with a piston (81) and two channels. The spray action is triggered by manual release (58) of a locking mechanism (74). The spring is outside the fluid storage zone, and acts on the piston to force a small volume of the fluid out of the cylinder (53) at a pressure of 1-5 MPa (10-50 bar). The distribution of the droplet sizes can be adjusted, with a mean droplet size of ≤ 50 mu m. The mass flow through the jet (60) is ≤ 0.4 g/second.

Device for discharging liquids, a cartridge suited therefor, and system comprised of the device for discharging liquids and of the cartridge

The invention relates to a propellant gas-free device for discharging liquids, to a cartridge, which is adapted thereto and which is provided for storing the liquid, and to the ensemble comprised of both the device and cartridge. The invention consists of a device (1) for supplying pressure and for accommodating a cartridge (10), and of a cartridge (10) inside of which a discharging device (29) is integrated.

Blocking device for a sprung lock with a spring operation

The useful life of a device needs to be limited, where hygienic, medical or technical grounds exist. A device which cannot be influenced by the user is thus required, which reliably, effectively and terminally prevents the further use of the device, as soon as the given number of operations is achieved. A locking device with spring operation and a counter is provided on said device and housed in a two-piece housing, the both parts of which are mounted such as to rotate relative to each other and the above can be blocked by a pre-tensioned leaf spring. The leaf spring is originally housed in a recess in the wall of the one housing piece. As soon as the permitted number of operations is achieved, a pin extends the leaf spring from the rest position thereof. The leaf spring then extends into a recess in the wall of the other housing piece such that the both housing pieces can no longer be rotated relative to each other. The pin can be located within the display of the counter. The blocking device can only be overcome with a force great enough to destroy the device. The device is suitable for blocking a high-pressure nebuliser or a needleless injector, by means of which a fluid is atomised to give an aerosol or a fluid is injected into a biological tissue.

Nozzle system for a liquid discharge device, comprising a nozzle and nozzle holder and/or coupling nut

The invention relates to a nozzle system for a liquid discharge device, comprising a nozzle and a device which fixes the nozzle in the discharge device. The device comprises a liquid reservoir which pressurises the liquid through a nozzle in order to discharge liquid. The nozzle is fixed to the discharge device by a holding device. Said holding device can be automatically maintained by a second holding device, e.g. in the form of a coupling nut, or the coupling nut is the holding device. According to the invention, at least one part of the outer surface of the holding device is micro or nanostructured.

Atomizer provided with a monitoring device for counting actuations of the atomizer

The invention relates to an atomizer (1) comprising an insertable container (3) and a monitoring device (20) for counting actuations of the atomizer. The monitoring device is arranged in a detachable housing part (15) and directly records movements of the container during an atomizing step, an air flow in the region of a mouth piece and/or the production of an aerosol, in order to detect an actual discharge of fluid and to count the number of actuations of the atomizer. Preferably, the respective moment in time when the atomizer is actuated is detected and stored in order to improve monitoring and user guidance.

Atomiser

The invention relates to an atomiser (1) for a fluid (2), comprising a pressure generator (5) which is used to convey and atomise the fluid, in particular, in the form of an inhaler. In order to improve user guidance, the atomiser comprises a signal device (24) which is used to produce at least one acoustic and/or vibratory signal, in particular, during an atomising step.

Atomiser comprising coding means

Es werden ein Zerstäuber (1) für ein Fluid und ein in den Zerstäuber einsetzbarer Behälter (3) mit dem Fluid vorgeschlagen. Zur Verbesserung der Sicherheit bei der Benutzung ist vorgesehen, dass der Zerstäuber ein erstes Kodiermittel (24) aufweist und dem Behälter ein zweites Kodiermittel (25) zugeordnet ist, so dass der Behälter nur bei passender Kodierung in den Zerstäuber einsetzbar oder mit diesem verwendbar ist. Vorzugsweise weist die dem Behälter zugeordnete Kodierung eine eindeutige Identifizierung für das im Behälter befindliche Fluid auf.

Locking-stressing mechanism for a miniaturised high pressuriser

A locking tensioning mechanism for a miniaturised high pressure generator is disclosed, which mechanism will allow delivery of a set volume of a liquid, and the volume to be delivered by a high pressure generator can be altered subsequently by adjusting one of the stops of the spring component, which locking tensioning mechanism may be used in a high pressure generator for producing an inhalable aerosol or in a needleless injector for injecting a volume of a liquid into animal or plant tissue.

Atomiser comprising a counter and an end of operation lock

An atomiser for a fluid, in particular for medical aerosol therapy, is proposed. In order to allow simplified operation and improved safety in use, the atomiser has a counter device for counting the operations of the atomiser and the number of containers inserted, wherein the atomiser is locked against further operation and/or against removal of the current container or insertion of a new container, if a certain number of operations of the atomiser and/or a certain number of containers inserted has/have been reached or exceeded.

Method and device for dosing medicaments

Es werden ein Verfahren und eine Vorrichtung zum Dosieren eines Arzneimittels, vorzugsweise einer Flüssigkeit, vorgeschlagen. Um eine verbesserte Dosiergenauigkeit zu erreichen, wird ein erstes, in Chargen hergestelltes Bauteil, wie eine Formdichtung, mit einem zweiten Bauteil, wie einem Förderrohr, einer passenden Gruppe kombiniert, wobei die passende Gruppe in Abhängigkeit von mindestens einer maßgeblichen signifikanten Größe der jeweiligen Charge ausgewählt wird und sich durch eine wesentliche Größe des zweiten Bauteils auszeichnet, um die Abdichtung zwischen diesen Bauteilen zu optimieren. A method and an apparatus for dosing a drug, preferably a fluid, are proposed. To achieve improved metering accuracy, a first batch-produced component, such as a molded seal, is combined with a second component, such as a production tubing, of an appropriate set, with the appropriate set being selected in response to at least a significant significant size of the particular batch and is characterized by a significant size of the second component in order to optimize the seal between these components.

Blocking device for a locking stressing mechanism having a spring-actuated output drive device

A locking-stressing-mechanism with spring-actuated output drive and a counter with which an apparatus of this kind is fitted, accommodated in a two part housing the two parts of which are mounted to be rotatable relative to each other, can be blocked by means of a pre-stressed leaf spring. The leaf spring is initially accommodated in a recess in the wall of one housing part. As soon as the permitted number of actuations has been reached a push rod pushes the leaf spring out of its resting position. The leaf spring then jumps into a recess in the wall of the other housing part and the two housing parts can no longer be rotated relative to each other. The push rod may be mounted on the pointer of the counter. This blocking device can only be overcome by the application of a force which is sufficient to destroy the device. The device is suitable for blocking a high pressure atomiser or a needleless injector with which a fluid is atomised to form an aerosol or a fluid is injected into a biological tissue.

Atomizer and filter

Es werden ein Zerstäuber für ein Fluid, insbesondere zur medizinischen Aerosol-Therapie, sowie ein Filter für den Zerstäuber zur Verhinderung einer Verkeimung vorgeschlagen. Der Zerstäuber weist eine Schutzeinrichtung zur Verhinderung einer Verkeimung des vorzugsweise konservierungsmittelfreien Fluids auf. Als Schutzeinrichtung ist insbesondere der Filter einsetzbar. So kann auch bei mehrfacher Verwendung des Zerstäubers eine Verkeimung des Fluids über die Nutzungsdauer des Zerstäubers verhindert werden. A nebulizer for a fluid, in particular for medical aerosol therapy, and a filter for the nebulizer for preventing microbial contamination are proposed. The atomizer has a protective device for preventing bacterial contamination of the preferably preservative-free fluid. As a protective device, in particular the filter can be used. Thus, even with repeated use of the atomizer microbial contamination of the fluid over the useful life of the atomizer can be prevented.

Inhalator

The inhalator (1) has a mechanical operated pressure generator (5) designed as a pump, where the pressure generation and/or the spraying of the inhalator takes place via spring force. A delivery nozzle is provided for delivery of a drug preparation unit (2) as an aerosol (14) into an orifice (13). An auxiliary device (23) is provided with a chamber (24) for intermediate storage of an aerosol. The chamber is arranged downstream of the delivery nozzle. The auxiliary device and/or the chamber are designed in cylindrical, oblong and conical shape.

Apparatus for the dispensing of liquids, container cartridge suitable for this, and system comprising the apparatus for the dispensing of liquids, and the container cartridge

The present invention relates to a propellant-gas-free apparatus for the dispensing of liquids, a container cartridge suitable for this for storing the liquid and the ensemble comprising both. The invention comprises a device for the exertion of pressure and for accommodating a container cartridge and a container cartridge in which the dispensing facility is integrated.

Reforming tool with a rotatable base body

The tool has a rotatable base member having a profiled bending roller (13) that is mounted on a circular track and is rotatable about a rotation axis. The bending roller is arranged on a radially movable slide (11) that is movable between two positions, where one of the positions defines a maximum working aperture for the tool by a spring-loaded lever (9) with an axial configuration, and another position defines a minimum working aperture for the tool. The lever includes an end that faces a pressing member (5) with a roller (10) that is rolled on the pressing member. An independent claim is also included for an inhaler cartridge comprising a plastic container.

Method for coating a surface of a component

The invention relates to a method for coating a surface (44), in particular a micro-structured surface, of a component (55) comprising different materials, in particular glass and silicon, wherein first the surface (44) is activated and then coated, wherein an oxidizing solution, a base solution or an acid-oxidizing solution is used to activate the surface (44).

Medical device having a counter having a preset counting range, device having counter variation

The invention relates to a hand-held medical device having a counter, preferably a dose dispenser such as an atomizer for dispensing dosed amounts of a drug preparation. The mechanical counter comprises a plurality of individual components, of which at least one is designed in such a way that said component can be installed in a quasi-subsequent manner as the last part after the assembly of the atomizer. Said component, with which a characteristic counter function such as preferably the display of the count is associated, is irreversibly connected to the housing of the atomizer. By installing a counter component subsequently, the design of the counter, for example the counting range, can be postponed until the time at which the drug formulation is fixed, in other words the dosage specifications with which the device is to be used. A preferred example is a liquid atomizer having a spindle/rider counter, wherein a rider to be installed differently from case to case is attached to a housing part from outside as an individual component. When said housing part is rotated relative to another housing part, a counter spindle supported there is driven. The rider is located on said counter spindle as the component that indicates the count. The rider on said counter spindle forms not only the indicator of the counter; the position of the rider on the spindle determines the counting range and the triggering of a blocking mechanism when the end of the counting range is reached.