25-08-2022 дата публикации
Номер: US20220266557A1
Принадлежит:
Disclosed herein are three-dimensional porous tubular scaffolds for cardiovascular, periphery vascular, nerve conduit, intestines, bile conduct, urinary tract, and bone repair/reconstruction applications, and methods and apparatus for making the same. 1. A method of making a three-dimensional tubular scaffold by an apparatus for manufacturing the three-dimensional porous tubular scaffold , the method comprising: a base;', 'an XYZ position system connected to said base, wherein said XYZ position system provides a X-axis, a Y-axis and a Z-axis, thereby providing motions along said X-axis, said Y-axis and said Z-axis;', 'a material delivery system that is mounted upon and is moved by said XYZ position system along said X-axis, said Y-axis and said Z-axis;', 'a rotary rod driver connected to said base, said rotary rod driver being computer-controlled, wherein said rotary rod driver provides rotation around a rotational axis, wherein said rotational axis is parallel to said Y-axis, and wherein said rotary rod driver is programmed to rotate, stop and rotate back and forth at desired speeds;', 'a rod having an outside diameter, said rod being mounted in and rotatingly driven by said rotary rod driver, said rod being located underneath said material delivery system, and said rod being equipped with a freeze mechanism, wherein said freeze mechanism is a cooling coil inside said rod;', 'wherein said apparatus is controlled so as to directly deposit a continuous filament of a material to form a deposited filament in a pre-designed geometric pattern on said rod or on a previously deposited layer, as a result of motions of said material delivery system driven by said XYZ position system and said rod driven by said rotary rod driver, and thereby forming said three-dimensional porous tubular scaffold; and', 'wherein said three-dimensional porous tubular scaffold has an inside diameter that is substantially equal to said outside diameter of said rod;, 'providing the apparatus ...
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