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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 3638. Отображено 100.
05-07-2012 дата публикации

Methods for preparing ethylene glycol from polyhydroxy compounds

Номер: US20120172633A1
Автор: Aiqin Wang, Mingyuan Zheng, Tao Zhang, Zhijun TAI
Принадлежит: Dalian Institute of Chemical Physics of CAS

This invention provides methods for producing ethylene glycol from polyhydroxy compounds such as cellulose, starch, hemicellulose, glucose, sucrose, fructose, fructan, xylose and soluble xylooligosaccharides. The methods uses polyhydroxy compounds as the reactant, a composite catalyst having active components comprising one or more transition metals of Groups 8, 9, or 10, including iron, cobalt, nickel, ruthenium, rhodium, palladium, iridium, and platinum, as well as tungsten oxide, tungsten sulfide, tungsten hydroxide, tungsten chloride, tungsten bronze oxide, tungsten acid, tungstate, metatungstate acid, metatungstate, paratungstate acid, paratungstate, peroxotungstic acid, pertungstate, heteropoly acid containing tungsten. Reacting at a temperature of 120-300° C. and a hydrogen pressure of 1-13 MPa under hydrothermal conditions to accomplish one-step catalytic conversion. It realizes efficient, highly selective, high yield preparation of ethylene glycol and propylene glycol from polyhydroxy compounds. The advantage of processes disclosed in this invention include renewable raw material and high atom economy. At the same time, compared with other technologies that converts biomass raw materials into polyols, methods disclosed herein enjoy advantages including simple reaction process, high yield of targeted products, as well as easy preparation and low cost for the catalysts.

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Номер записи: 1
23-08-2012 дата публикации

Processes for the production of hydrogenated products

Номер: US20120215014A1
Автор: Bernard Duane Dombek, Brian Terry Keen, Brooke Ashley Albin, Dilum Dunuwila, Leo E. Manzer, Nye A. Clinton, Olan S. Fruchey
Принадлежит: Bioamber International SARL

A process for making a hydrogenated product includes providing a clarified DAS-containing fermentation broth, distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes MAS, at least some DAS, and at least about 20 wt % water, cooling and/or evaporating the bottoms, and optionally adding an antisolvent to the bottoms, to attain a temperature and composition sufficient to cause the bottoms to separate into a DAS-containing liquid portion and a MAS-containing solid portion that is substantially free of DAS, separating the solid portion from the liquid portion, recovering the solid portion, hydrogenating the second solid portion in the presence of at least one hydrogenation catalyst to produce the hydrogenated product comprising at least one of THF, GBL or BDO, and recovering the hydrogenated product.

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Номер записи: 2
20-06-2013 дата публикации

METHOD FOR CHEMICAL MODIFICATION OF A GRAPHENE EDGE, GRAPHENE WITH A CHEMICALLY MODIFIED EDGE AND DEVICES INCLUDING THE GRAPHENE

Номер: US20130157034A1
Автор: CHOI Jaeyoung, CHOI Won Mook, HONG Byung Hee
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A method for chemical modification of graphene includes dry etching graphene to provide an etched graphene; and introducing a functional group at an edge of the etched graphene. Also disclosed is graphene, including an etched edge portion, the etched portion including a functional group. 1. Graphene , comprising:an etched edge portion, wherein the etched edge portion comprises a functional group.2. The graphene according to claim 1 , wherein the functional group is introduced at the etched edge portion by contacting with hydroxide ions.3. The graphene according to claim 1 , wherein the functional group is introduced by contacting with water claim 1 , alcohol or a combination thereof.4. The graphene according to claim 3 , wherein the functional group is introduced at the etched edge portion by contacting with steam.5. The graphene according to claim 1 , wherein the graphene is a graphene sheet formed of polycyclic aromatic molecules with covalently bonded carbon atoms claim 1 , and further wherein the graphene sheet comprises about 1 to about 300 layers of the graphene in a thickness direction claim 1 , and having dimensions of greater than or equal to about 1 mm along each of a transverse direction and a longitudinal direction.6. The graphene according to claim 1 , wherein the functional group is at least one selected from the group consisting of —C═O claim 1 , —COOH claim 1 , —C—OH claim 1 , —CH═O claim 1 , —COO claim 1 , —COOR wherein R represents C-Calkyl and a combination thereof.7. A device comprising graphene claim 1 , wherein the graphene comprises:an etched edge portion, wherein the etched edge portion comprises a functional group.8. A graphene sheet claim 1 , comprising:a plurality of layers of graphene, wherein a layer of the graphene has an etched edge portion comprising a functional group.9. The graphene sheet according to claim 8 , wherein the functional group is at least one selected from the group consisting of —C═O claim 8 , —COOH claim 8 , —C—OH ...

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Номер записи: 3
12-09-2013 дата публикации

MULTICOMPONENT SYSTEM OF RESUVASTATIN CALCIUM SALT AND SORBITOL

Номер: US20130237553A1
Автор: Blatter Fritz, Hafner Andreas, Siebenhaar Bernd, Szelagiewicz Martin
Принадлежит: BASF SE

A novel solid form of Rosuvastatin comprises as the active ingredient a salt of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxyhept-6-enoic acid] and sorbitol. The crystal comprising the two components, and minor amounts of water, shows improved properties such as crystal-lization behaviour and stability. 1. A single phase solid form of a bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl](3R ,5S)-3 ,5-dihydroxyhept-6-enoic acid] salt comprising sorbitol.2. Solid form of wherein the salt of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl](3R claim 1 ,5S)-3 claim 1 ,5-dihydroxyhept-6-enoic acid] is a calcium salt.3. Solid form according to wherein sorbitol is D-sorbitol.4. Solid form according to containing 0.3 to 1.5 molar parts claim 1 , preferably 0.3 to 1.1 molar parts claim 1 , of D-sorbitol on 1 molar unit of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl](3R claim 1 ,5S)-3 claim 1 ,5-dihydroxyhept-6-enoic acid].5. Solid form according to claim 1 , which is a molecular crystal.6. Solid form according to claim 1 , consisting essentially of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)-amino]pyrimidin-5-yl](3R claim 1 ,5S)-3 claim 1 ,5-dihydroxyhept-6-enoic acid] calcium salt claim 1 , D-sorbitol claim 1 , and water as minor component by weight.7. Solid form according to claim 1 , which is a crystalline form of bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl](3R claim 1 ,5S)-3 claim 1 ,5-dihydroxyhept-6-enoic acid] calcium salt with D-sorbitol claim 1 , and/or hydrates thereof claim 1 , exhibiting a X-ray powder diffraction pattern with characteristic peaks expressed in d-values (Å): 4.85 (s) claim 1 , 4.75 (s) claim 1 , 4.70 (s) claim 1 , 4.59 (s) claim 1 , 4.49 (vs) claim 1 , 4.33 (s) claim 1 , 4.23 (s) claim 1 , 4.00 ...

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Номер записи: 4
26-09-2013 дата публикации

PROCESS FOR PREPARING BOSENTAN MONOHYDRATE AND ITS INTERMEDIATED

Номер: US20130253195A1
Автор: Andretto Mauro, Colli Corrado, Cotarca Livius, Maragni Paolo, Melloni Alfonso, Melotto Elisa, Michieletto Ivan, Verzini Massimo, Volpicelli Raffaella
Принадлежит: ZACH SYSTEM SPA

The present invention relates to a process for preparing Bosentan Monohydrate; in particular, the present invention provides the preparation of the novel 4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(2-pyrimidinyl)-pyrimidin-4-yl]-benzenesulfonamide sodium salt as an ethylene glycol solvate (Bosentan sodium salt ethylene glycol solvate), which is a useful intermediate for obtaining Bosentan Monohydrate in a pure form. 2. Crystalline form of ethylene glycol solvate of Bosentan sodium salt according to claim 1 , having a XRPD comprising peaks expressed at the following degrees two-theta values: 6.4 claim 1 , 8.4 claim 1 , 9.0 claim 1 , 9.9 claim 1 , 12.0 claim 1 , 18.2 and 20.4 claim 1 , plus or minus 0.2 degrees.4. A process according to claim 3 , wherein Bosentan sodium salt ethylene glycol solvate is collected as a wet cake claim 3 , wherein residual ethylene glycol is about 20% to about 40%.5. A process for preparing Bosentan sodium salt as ethylene glycol solvate according to claim 3 , wherein the compound of formula (III) is obtained by reacting sodium methoxide (CHONa) with ethylene glycol.8. Bosentan sodium salt according to claim 7 , wherein the total content of dimer and pyrimidinone impurities is less than about 0.2% as measured by HPLC.9. Bosentan sodium salt according to claim 8 , wherein the total content of dimer and pyrimidinone impurities is less than about 0.1% as measured by HPLC.10. Bosentan sodium salt of formula (IV) according to claim 7 , having a XRPD comprising peaks expressed at the following degrees two-theta values 6.6 claim 7 , 7.8 claim 7 , 9.0 claim 7 , 10.2 and 25.2 claim 7 , plus or minus 0.2 degrees.12. A process according to claim 11 , wherein the solution of Bosentan sodium salt ethylene glycol solvate of step c) is provided by dissolving Bosentan sodium salt ethylene glycol solvate as obtained according to step b) in a mixture of ethanol claim 11 , acetone and cyclohexane as a solvent claim 11 , wherein at least 80% ...

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Номер записи: 5
06-02-2014 дата публикации

Methods for producing bioderived propylene glycol

Номер: US20140039224A1
Автор: Brad Zenthoefer, Chicheng Ma, John G. Soper, Kevin J. Adlaf, Paul D. Bloom, William Chris HOFFMAN
Принадлежит: Archer Daniels Midland Co

In the process of distilling a polyol product mixture including one or both of a biobased propylene glycol and a biobased ethylene glycol from the reaction of hydrogen with a biobased feed, it has been discovered that undesirable epoxides can form, and the present invention provides means for guarding against their formation, for removing epoxides which do form by particular methods of distilling, and for removing the epoxides from a finished, otherwise commercially acceptable biobased glycol product.

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Номер записи: 6
07-01-2021 дата публикации

CONTINUOUS OR SEMI-CONTINUOUS PROCESS FOR THE PREPARATION OF ETHYLENE GLYCOL AND CATALYST SYSTEM FOR USE THEREIN

Номер: US20210002192A1
Автор: Dekker Paula, McKay Benjamin, SINGH Jagdeep, van der Waal Jan Cornelis
Принадлежит:

A continuous or semi-continuous process for the preparation of ethylene glycol from a carbohydrate source including: 1. A continuous or semi-continuous process for the preparation of ethylene glycol from a carbohydrate source including:reacting, in a reactor, at a temperature in the range from equal to or more than 170° C. to equal to or less than 270° C., at least a portion of a carbohydrate source in the presence of hydrogen, a solvent, and a catalyst system, to yield ethylene glycol;wherein the catalyst system includes:a homogeneous catalyst, which homogeneous catalyst contains tungsten; anda heterogeneous catalyst, which heterogeneous catalyst contains one or more transition metals from groups 8, 9 and 10 of the Periodic Table of the Elements supported on a carrier;and wherein continuously or periodically additional heterogeneous catalyst is added to the reactor.2. The process according to claim 1 , wherein the selectivity towards ethylene glycol is maintained by continuously or periodically adding additional heterogeneous catalyst to the reactor.3. The process according to claim 2 , wherein the ethylene glycol selectivity is maintained below a threshold of 85% by continuously or periodically adding additional heterogeneous catalyst to the reactor.4. The process according to claim 2 , wherein the ethylene glycol selectivity is maintained within a range of equal to or more than 35% to equal to or less than 85% by continuously or periodically adding additional heterogeneous catalyst to the reactor.5. The process according to any one of to claim 2 , wherein the ethylene glycol selectivity is continuously or periodically determined and compared with a one or more pre-set thresholds and wherein additional heterogeneous catalyst is provided to the reactor if such a threshold is reached or exceeded.6. The process according to any one of to claim 2 , wherein the catalyst system is a catalyst system including:a) a homogeneous catalyst, that is residing in the reactor, ...

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Номер записи: 7
07-01-2021 дата публикации

Core-Shell Copolymer, Method for Preparing the Same and Thermoplastic Resin Composition Containing the Same

Номер: US20210002193A1
Автор: Kim Yoon Ho, Lee Hye Rim, Yoo Ki Hyun
Принадлежит: LG CHEM, LTD.

A core-shell copolymer, a method of making the same, and a thermoplastic resin including the same are disclosed herein. In some embodiments, a core-shell copolymer including a core and a shell surrounding the core, wherein the core includes a first alkyl(meth)acrylate monomer-derived repeating unit having 1 to 8 carbon atoms and a terminal-modified polydimethylsiloxane crosslinking agent-derived crosslinking part wherein the terminal-modified polydimethylsiloxane crosslinking agent includes a second alkyl(meth)acrylate monomer-derived modified part at both terminals of the polydimethylsiloxane. 1. A core-shell copolymer comprising:a core; anda shell surrounding the core,wherein the core includes a first alkyl(meth)acrylate monomer-derived repeating unit having 1 to 8 carbon atoms and a terminal-modified polydimethylsiloxane crosslinking agent-derived crosslinking part, andwherein the terminal-modified polydimethylsiloxane crosslinking agent includes a second alkyl(meth)acrylate monomer-derived modified part at both terminals of the polydimethylsiloxane.2. The core-shell copolymer of claim 1 , wherein the core has an average particle diameter of 150 nm to 500 nm.3. The core-shell copolymer of claim 1 , wherein the core has an average particle diameter of 185 nm to 260 nm.5. The core-shell copolymer of claim 4 , wherein Rand Rare each independently an alkylene group having 1 to 8 carbon atoms claim 4 , and n is 10 to 330.6. The core-shell copolymer of claim 1 , wherein the core includes 70 parts by weight to 95 parts by weight of the first alkyl(meth)acrylate monomer-derived repeating unit and 0.01 parts by weight to 5 parts by weight of the terminal-modified polydimethylsiloxane crosslinking agent-derived crosslinking part claim 1 , based on 100 parts by weight of the core-shell copolymer.7. The core-shell copolymer of claim 1 , wherein the core includes 83 parts by weight to 88 parts by weight of the first alkyl(meth)acrylate monomer-derived repeating unit and 0.1 ...

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Номер записи: 8
07-01-2021 дата публикации

PROCESS AND SYSTEMS FOR OBTAINING 1,4-BUTANEDIOL FROM FERMENTATION BROTHS

Номер: US20210002195A1
Автор: Garikipati SVB Janardhan, Japs Michael, Sonico Ishmael M.
Принадлежит:

A process of purifying 1,4-butanediol (1,4-BDO) from a fermentation broth including separating solid materials, salts and water, and subjecting the resulting material to a two, three or four column distillation system, that can include a wiped film evaporator to produce a purified 1,4-butanediol. 1. A process of purifying 1 ,4-butanediol (1 ,4-BDO) comprising:(a) subjecting a crude 1,4-BDO mixture to a first column distillation procedure to remove materials with a boiling point lower than 1,4-BDO from the crude 1,4-BDO mixture to produce a first 1,4-BDO-containing product stream; and(b) subjecting the first 1,4-BDO-containing product stream to a second column distillation procedure to remove materials with boiling points higher than 1,4-BDO as a first high-boilers stream, to produce a purified 1,4-BDO product, wherein the purified 1,4-BDO product is collected from a side-draw of the second column distillation procedure.2. The process of claim 1 , further comprising (c) subjecting the first high-boilers stream to wiped-film evaporation (WFE) to produce a first WFE distillate and subjecting the first WFE distillate to step (b).3. The process of further comprising (d) subjecting the first 1 claim 1 ,4-BDO-containing product stream claim 1 , prior to performing step (b) claim 1 , to an intermediate column distillation procedure to remove materials with boiling points higher than 1 claim 1 ,4-BDO as a second high-boilers stream.4. The process of claim 3 , further comprising (c) subjecting the second high-boilers stream to wiped-film evaporation (WFE) producing a second WFE distillate and subjecting the second WFE distillate to step (d).5. The process of further comprising (e) treating the first 1 claim 3 ,4-BDO-containing product stream with a hydrogenation reaction prior to performing step (b).6. The process of further comprising (f) treating the purified 1 claim 1 ,4-BDO product with a hydrogenation reaction.7. The process of wherein the crude 1 claim 1 ,4-BDO mixture ...

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Номер записи: 9
04-01-2018 дата публикации

WATER-SOLUBLE PACKETS

Номер: US20180002084A1
Автор: Friedrich Steven G., KEULEERS Robby Renilde Francois, Nii Shinsuke, Yeung Lee K.
Принадлежит:

The disclosure provides a water soluble pouch including at least two sealed compartments, the pouch including outer walls including water soluble film including a water soluble resin, and an inner wall including water soluble film including a water soluble resin, the outer wall films being sealed to the inner wall film, the outer wall films being characterized by: a dissolution time of 300 seconds or less, the water soluble resin of the outer wall films having a viscosity in a range of 14.5 cP to 25cP, and a pouch strength of at least 200 N, and the inner wall film being characterized by: a dissolution time of 300 seconds or less, the water soluble resin of the inner film having viscosity in a range of 12 cP to 14.5 cP, and a tackiness value of at least 1500 g/s. 1. A water soluble pouch defining an interior pouch volume , the pouch comprising at least two water-soluble films , wherein a film of the at least two water-soluble films comprises a polyvinyl alcohol resin comprising a polyvinyl alcohol copolymer comprising an anionic monomer unit , optionally one or more of maleic acid , monoalkyl maleate , dialkyl maleate monomethyl maleate dimethyl maleate , maleic anhydride , alkali metal salts of the foregoing , esters of the foregoing , and combinations of the foregoing , and wherein the water-soluble film comprising a polyvinyl alcohol copolymer comprising an anionic monomer unit is sealed to another film using a sealing solution comprising water , one or more diols and/or glycols , and a surfactant.2. The water-soluble pouch of claim 1 , wherein the surfactant is one or more selected from polyoxyethylenated polyoxypropylene glycols claim 1 , alcohol ethoxylates claim 1 , alkylphenol ethoxylates claim 1 , tertiary acetylenic glycols and alkanolamides (nonionics) claim 1 , polyoxyethylenated amines claim 1 , quaternary ammonium salts and quaternized polyoxyethylenated amines (cationics) claim 1 , amine oxides claim 1 , N-alkylbetaines and sulfobetaines ( ...

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Номер записи: 10
04-01-2018 дата публикации

CONTINUOUS PROCESS FOR PREPARING ETHYLENE GLYCOL FROM A CARBOHYDRATE SOURCE

Номер: US20180002259A1
Автор: Gruter Gerardus Johannes Maria, van der Waal Jan Cornelis
Принадлежит:

Ethylene glycol is prepared from a carbohydrate source by reaction of the carbohydrate source with hydrogen in a continuous process, 1. Continuous process for preparing ethylene glycol from a carbohydrate source by reaction of the carbohydrate source with hydrogen ,wherein hydrogen, the carbohydrate source and a liquid diluent are continuously fed into a continuous stirred tank reactor wherein a catalyst system is present, which catalyst system comprises a tungsten compound and at least one hydrogenolysis metal selected from the groups 8, 9 or 10 of the Periodic Table of the Elements, to achieve the reaction between the carbohydrate source and hydrogen to ethylene glycol;wherein continuously a product mixture comprising ethylene glycol and diluent is removed from the continuous stirred tank reactor; andwherein continuously or periodically further at least a tungsten compound is added to the continuous stirred tank reactor (CSTR).2. Continuous process according to claim 1 , wherein the amount of tungsten added to the CSTR is such that the concentration thereof in the CSTR is substantially constant.3. Continuous process according to claim 1 , wherein the weight ratio of tungsten to the at least one hydrogenolysis metal claim 1 , all calculated as metals claim 1 , in the CSTR is in the range of 2 to 50 wt/wt.4. Continuous process according to claim 1 , wherein the weight ratio of tungsten calculated as metal to carbohydrate source in the CSTR is in the range of 5 to 50 wt/wt.5. Continuous process according to claim 1 , wherein the tungsten compound that is continuously or periodically added to the CSTR has an oxidation state of at least +2.6. Continuous process according to claim 1 , wherein the weight ratio of the at least one hydrogenolysis metal and carbohydrate that is introduced into the CSTR is in the range of 1:25 to 1:250 wt/wt.7. Continuous process according to claim 1 , wherein the tungsten compound that is continuously or periodically added to the CSTR claim ...

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Номер записи: 11
03-01-2019 дата публикации

HYDROGENATION OF OXYGENATED MOLECULES FROM BIOMASS REFINING

Номер: US20190002381A1
Автор: HALLAC Bassem, Jansen Robert, LAPIDOT Noa, LAWSON James Alan, Madsen Lee, MATIS Neta, Travisano Philip, ZVIELY Michael
Принадлежит:

The present disclosure relates to methods, processes, and systems for utilizing the dehydrogenation of 2-butanol for hydrogen consuming reactions of biomass or biomass-derived molecules. 1103-. (canceled)104. A method for producing 2-butanone and a conversion product , the method comprising:dehydrogenating 2-butanol to yield 2-butanone, thereby releasing hydrogen;using hydrogen released from the dehydrogenating in a conversion reaction, wherein the conversion reaction converts a biomass-derived molecule to a conversion product; andrecovering 2-butanone and the conversion product.105. The method of claim 104 , wherein the biomass-derived molecule is derived from lignocellulosic biomass.106. The method of claim 105 , wherein the biomass-derived molecule is selected from a saccharide claim 105 , a dehydrated saccharide claim 105 , a halodehydrated saccharide claim 105 , a dehydrated and partially-hydrogenated saccharide claim 105 , and a hydrogenated saccharide claim 105 , or a combination thereof.107. The method of claim 104 , wherein the biomass-derived molecule is selected from a monosaccharide claim 104 , an oligosaccharide claim 104 , furfural claim 104 , halofurfural claim 104 , methyl furfural claim 104 , furfuryl alcohol claim 104 , methyl furfuryl alcohol claim 104 , (methoxymethyl)-methyl furfural claim 104 , hydroxymethylfurfural claim 104 , 2-methylfuran claim 104 , dimethylfuran claim 104 , 2 claim 104 ,5-bis(hydroxymethyl)furan claim 104 , 5-hydroxymethyl-2-[(1-methylethoxy)methyl] furan claim 104 , 2-methyl-5[(1-methylmethoxy)methyl] furan claim 104 , bis(1-methoxyethoxy)-methyl furan claim 104 , tetrahydrofuran claim 104 , levoglucosenone claim 104 , 1 claim 104 ,2 claim 104 ,6-hexanetriol claim 104 , 1 claim 104 ,2 claim 104 ,5-pentanetriol claim 104 , 1 claim 104 ,2 claim 104 ,4-butanetriol claim 104 , 2 claim 104 ,4-dihydroxy butanoic acid claim 104 , 2 claim 104 ,4-hydroxybutanoic acid claim 104 , succinic acid claim 104 , malic acid claim 104 , ...

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Номер записи: 12
05-01-2017 дата публикации

COMPOSITIONS AND METHODS FOR IMPROVING REBAUDIOSIDE X SOLUBILITY

Номер: US20170002034A1
Автор: CHATURVEDULA VENKATA SAI PRAKASH, Ma Gil, MARKOSYAN Avetik, Prakash Indra
Принадлежит:

Polymorphic and amorphous forms of Rebaudioside X and methods for preparing the same are provided herein. Also provided herein are Rebaudioside X complexes and methods for preparing the same. Sweetener compositions and sweetened compositions comprising Rebaudioside X forms and Rebaudioside X complexes are described, as well as and methods of their preparation. Methods of improving the flavor and/or temporal profile of sweetenable compositions, such as beverages, are also provided herein. 1. A method for preparing amorphous Rebaudioside X comprising:(i) heating a mixture comprising water and Rebaudioside X to a temperature between about 100° C. to about 130° C.(ii) cooling the mixture; and(iii) removing the solvent from the mixture to provide amorphous Rebaudioside X.2. The method of claim 1 , wherein the Rebaudioside X in (i) is Form A Rebaudioside X.3. The method of claim 1 , wherein the Rebaudioside X in (i) is Material E Rebaudioside X.4. (canceled)5. (canceled)6. The method of claim 1 , wherein the mixture is heated to a temperature from about 120° C. to about 125° C.762.-. (canceled)63. The method of claim 1 , wherein the mixture in (ii) is cooled to room temperature such that crash precipitation does not occur.64. The method of claim 63 , wherein the mixture is cooled at a rate of about 1° C. per minute.65. The method of claim 1 , wherein the solvent is removed by a process selected from the group consisting of decantation claim 1 , centrifugation claim 1 , filtration claim 1 , evaporation claim 1 , vacuum claim 1 , spray-drying and a combination thereof.66. The method of claim 65 , wherein the solvent is removed by spray-drying.67. The method of claim 1 , wherein the amorphous Rebaudioside X has a solubility of about 0.3% or greater.68. The method of claim 1 , wherein the amorphous Rebaudioside A has a solubility of about 1.0% or greater.69. A method for preparing amorphous Rebaudioside X comprising:(i) heating a mixture comprising ethanol and Rebaudioside X ...

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Номер записи: 13
04-01-2018 дата публикации

Method for producing tetrahydrofurane, 1,4-butanediol or gamma-butyrolactone

Номер: US20180002303A1
Автор: Alexander DUEFERT, Rolf Pinkos, Wolf-Steffen WEIßKER
Принадлежит: BASF SE

Processes for preparing tetrahydrofuran and/or butane-1,4-diol and/or gamma-butyrolactone are provided, including a process for preparing tetrahydrofuran (THF) from succinic acid that has been obtained by conversion of biomass, by conversion of the succinic acid to succinic anhydride, and hydrogenation of the succinic anhydride, with removal of certain secondary components.

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Номер записи: 14
04-01-2018 дата публикации

USE OF A FIRST FILM AND A SECOND FILM TO IMPROVE SEAL STRENGTH OF A WATER-SOLUBLE

Номер: US20180002647A1
Автор: COURCHAY Florence Catherine, KEULEERS Robby Renilde Francois, LABEQUE Regine, Renmans Marc Rene Bert, Souter Philip Frank
Принадлежит:

The present invention relates to the use of a first water-soluble film and a second water-soluble film to make a unit dose article and the use of said unit dose article. 1. Use of a first water-soluble film and a second water-soluble film in the manufacture of a water-soluble unit dose article optionally comprising a composition contained within the unit dose article , wherein the first water-soluble film and the second water-soluble film are sealed together along a seal area , in order to improve the seal strength in the seal area;wherein the first water-soluble film and the second water-soluble film are chemically different to one another and wherein the first water-soluble film has a first water capacity, and wherein the second water-soluble film has a second water capacity, wherein the first water capacity is less than the second water capacity, and wherein the difference between the water capacity of the first water soluble film and the second water-soluble film is between 0.01% and 1%;provided that when the composition is a fabric care or household care composition and a film comprises a blend of a polyvinyl alcohol homopolymer resin and an anionic polyvinyl alcohol copolymer resin, then both then first water soluble film and the second water soluble film comprise blends that include 65 wt. % or greater of an anionic polyvinyl alcohol copolymer resin; andprovided that when the composition is a fabric care or household care composition and a film comprises a blend of at least two anionic polyvinyl alcohol copolymer resins, then both then first water soluble film and the second water soluble film comprise blends of at least two anionic polyvinyl alcohol copolymer resins.2. The use according to to improve the seal strength in the seal area to reduce the volume of scrapped material during manufacture of water-soluble unit dose articles.3. The use according to claim 1 , wherein the first water-soluble film has a water capacity from 1% to 10%.4. The use according to ...

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Номер записи: 15
12-01-2017 дата публикации

METHODS AND HOST CELLS FOR ENHANCING PRODUCTION OF 1, 3-BUTANEDIOL

Номер: US20170009263A1
Автор: Conradie Alex Van Eck, KAMIONKA Mariusz Stanislaw
Принадлежит:

This application describes non-naturally occurring host cells for enhanced 1,3-butanediol (1,3-BDO) production, methods for producing 1,3-BDO using such non-naturally occurring host cells, and 1,3-BDO products produced by such non-naturally occurring host cells and methods. 1. A non-naturally occurring host cell capable of enhanced 1 ,3-butanediol production , comprising: (i) decrease or inhibit the activity of a polypeptide having the activity of an enzyme of EC 4.1.1.5, or', '(ii) decrease or prevent expression of a gene encoding a polypeptide having the activity of an enzyme of EC 4.1.1.5, and, '(a) a modification to either (i) decrease or inhibit the activity of a polypeptide having the activity of an enzyme of EC 1.2.1.10, or', '(ii) decrease or prevent expression of a gene encoding a polypeptide having the activity of an enzyme of EC 1.2.1.10,, '(b) a modification to eitherwherein, compared to an unmodified host cell, the non-naturally occurring host cell:(i) gains three reducing equivalents,(ii) gains three chemical species, wherein said chemical species are capable of transferring the equivalent of one electron in a redox reaction, or(iii) produces more 1,3-butanediol.2. The non-naturally occurring host cell of claim 1 , wherein the modifications comprise at least one gene knockout.3. The non-naturally occurring host cell of claim 1 , wherein the host comprises one or more exogenous nucleic acids encoding one or more polypeptides having the activity of one or more enzymes chosen from:(a) an enzyme of EC 2.3.1.9;(b) an enzyme of EC 1.1.1.36;(c) an enzyme of EC 1.1.1.157;(d) an enzyme of EC 2.8.3.-;(e) an enzyme of EC 1.2.99.6; and(g) an enzyme of EC 1.1.1.-.4. The non-naturally occurring host cell of claim 1 , wherein the host expresses one or more polypeptides having the activity of one or more enzymes chosen from:(a) an enzyme of EC 2.3.1.8; and(b) an enzyme of EC 2.7.2.15.5. The non-naturally occurring host cell of claim 3 , wherein the enzyme of EC 2.8.3 ...

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Номер записи: 16
09-01-2020 дата публикации

NI-AL2O3@AL2O3-SIO2 CATALYST WITH COATED STRUCTURE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Номер: US20200009538A1
Автор: Li Haitao, SUN Zijin, WANG Yongzhao, ZHANG Hongxi, ZHAO Lili, Zhao Yongxiang
Принадлежит:

A Ni—AlO@AlO—SiOcatalyst with coated structure is provided. The catalyst has a specific surface area of 98 m/g to 245 m/g, and a pore volume of 0.25 cm/g to 1.1 cm/g. A mass ratio of an AlOcarrier to active component Ni in the catalyst is AlO:Ni=100:4˜26, a mass ratio of the AlOcarrier to an AlO—SiOcoating layer is AlO:AlO—SiO=100:0.1˜3, and a molar ratio of Al to Si in the AlO—SiOcoating layer is 0.01 to 1. Ni particles are distributed on a surface of the AlOcarrier in an amorphous or highly dispersed state and have a grain size less than or equal to 8 nm, and the coating layer is filled among the Ni particles. 1. A Ni—AlO@AlO—SiOcatalyst with coated structure , comprising: Ni particles are distributed on a surface of an AlOcarrier in an amorphous or highly dispersed state as an active component for the catalyst and have a grain size less than or equal to 8 nm , a mass ratio of the AlOcarrier to an AlO—SiOcoating layer is AlO:AlO—SiO=100:0.1˜3 , a molar ratio of Al to Si in the AlO—SiOcoating layer is 0.01˜0.1:1 , and the coating layer is filled among the Ni particles.2. The Ni—AlO@AlO—SiOcatalyst with coated structure according to claim 1 , wherein the catalyst has a specific surface area of 98 m/g˜245 m/g claim 1 , and a pore volume of 0.25 cm/g˜1.1 cm/g claim 1 , and a mass ratio of the AlOcarrier to the active component Ni in the catalyst is AlO:Ni=100:4˜26.3. A preparation method of the Ni—AlO@AlO—SiOcatalyst with coated structure according to claim 1 , comprising the steps of:{'sub': 2', '3', '2', '3, 'impregnation step: loading the active component Ni onto the AlOcarrier using an impregnation method, Ni being distributed in tetrahedral and octahedral holes on an AlOsurface and growing into microcrystalline particles by using the tetrahedral and octahedral holes as nuclei;'}{'sub': 2', '3', '2', '2', '3', '2', '3', '2', '2', '3, 'deposition step: loading the AlO—SiOlayer in a depositing manner onto a surface of a Ni/AlOcatalyst obtained in the impregnation ...

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Номер записи: 17
10-01-2019 дата публикации

PROCESS FOR THE PREPARATION OF ETHYLENE GLYCOL FROM SUGARS

Номер: US20190010103A1
Автор: Larsen Morten Boberg, OSMUNDSEN Christian Mårup, TAARNING Esben
Принадлежит: Haldor Topsoe A/S

A process for the preparation of ethylene glycol and other C-Chydroxy compounds comprising the steps of hydrogenating a composition comprising C-Coxygenate compounds in the gas phase in the presence of a copper on carbon catalyst. 1. A process for the preparation of a C-Chydroxy compound ,comprising the steps of:{'sub': 1', '3, 'a) providing an oxygenate feed composition comprising a C-Coxygenate compound, and'}b) providing a hydrogenation catalyst material comprising Cu on carbon, then{'sub': 1', '3, 'c) reacting the composition of step a) with hydrogen in the presence of the catalyst of step b) and under conditions to provide gas phase hydrogenation of the oxygenate compound to obtain a hydrogenation product composition comprising the C-Chydroxy compound, and then'}d) recovering the hydrogenation product composition.2. The process according to claim 1 , wherein the process is performed under continuous conditions.3. The process according to claim 1 , wherein the oxygenate feed composition of step a) is brought into the gas phase by atomizing the oxygenate feed using a spray nozzle.4. The process according to claim 1 , wherein the oxygenate feed composition of step a) comprises one or more of the C-Coxygenate compounds selected from the group consisting of glycolaldehyde claim 1 , glyoxal claim 1 , pyruvaldehyde claim 1 , acetol and formaldehyde.5. The process according to claim 1 , wherein the oxygenate feed composition comprises at least two of the C-Coxygenate compounds selected from the group consisting of glycolaldehyde claim 1 , glyoxal claim 1 , pyruvaldehyde claim 1 , acetol and formaldehyde.6. The process according to claim 1 , wherein the C-Chydroxy compound is a C-Chydroxy compound.7. The process according to claim 1 , wherein the oxygenate feed composition of step a) is brought into the gas phase prior to step c).8. The process according to claim 1 , wherein the hydrogenation catalyst material of step b) has a loading of Cu on carbon in the range of ...

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Номер записи: 18
03-02-2022 дата публикации

Chromium-Catalyzed Production of Alcohols From Hydrocarbons

Номер: US20220033332A1
Автор: Carlos A. Cruz, Jared L. BARR, Kathy S. CLEAR, Masud M. Monwar, Max P. McDaniel, William C. Ellis
Принадлежит: Chevron Phillips Chemical Co LP

Processes for converting a hydrocarbon reactant into an alcohol compound and/or a carbonyl compound are disclosed, and these processes include the steps of forming a supported chromium catalyst comprising chromium in a hexavalent oxidation state, irradiating the hydrocarbon reactant and the supported chromium catalyst with a light beam at a wavelength in the UV-visible spectrum to reduce at least a portion of the supported chromium catalyst to form a reduced chromium catalyst, and hydrolyzing the reduced chromium catalyst to form a reaction product comprising the alcohol compound and/or the carbonyl compound. The supported chromium catalyst can be formed by heat treating a supported chromium precursor, contacting a chromium precursor with a solid support while heat treating, or heat treating a solid support and then contacting a chromium precursor with the solid support.

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Номер записи: 19
19-01-2017 дата публикации

Method for breakdown of formates

Номер: US20170015608A1
Автор: Helmut Kronemayer, Nicolas Marion, Rolf Pinkos
Принадлежит: BASF SE

A process for decomposing formates in formate-containing compositions of matter comprises reacting formate-containing compositions of matter in the presence of at least one heterogeneous catalyst comprising lanthanum and at a temperature of from 80 to 180° C. and a pressure of from 0.1 to 60 bar, the formate-containing compositions of matter having a pH of from 6.5 to 10

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Номер записи: 20
16-01-2020 дата публикации

METHOD FOR ACTIVATING A FIXED CATALYST BED WHICH CONTAINS MONOLITHIC SHAPED CATALYST BODIES OR CONSISTS OF MONOLITHIC SHAPED CATALYST BODIES

Номер: US20200016579A1
Автор: de Wispelaere Irene, Kotanjac Zeljko, Nilles Michael, PINKOS Rolf, Schreiber Michael, Schroeter Marie Katrin, Schwarz Michael
Принадлежит:

A process for activating a fixed catalyst bed is disclosed. The fixed catalyst bed includes monolithic shaped catalyst bodies or include monolithic shaped catalyst bodies including at a first metal selected from Ni, Fe, Co, Cu, Cr, Pt, Ag, Au and Pd, and a second component selected from Al, Zn and Si. The fixed catalyst bed, for activation, is treated with an aqueous base having a strength of not more than 3.5% by weight. The base is selected from alkali metal hydroxides, alkaline earth metal hydroxides and mixtures thereof. The fixed catalyst bed has a temperature gradient during the activation and the temperature differential between the coldest point in the fixed catalyst bed and the warmest point in the fixed catalyst bed is kept at not more than 50 K. 1. A process for activating a fixed catalyst bed comprising monolithic shaped catalyst bodies or consisting of monolithic shaped catalyst bodies comprising at least one first metal selected from Ni , Fe , Co , Cu , Cr , Pt , Ag , Au and Pd , and comprising at least one second component selected from Al , Zn and Si , and wherein the fixed catalyst bed , for activation , is subjected to a treatment with an aqueous base having a strength of not more than 3.5% by weight , wherein the base is selected from alkali metal hydroxides , alkaline earth metal hydroxides and mixtures thereof , and wherein the fixed catalyst bed has a temperature gradient during the activation and the temperature differential between the coldest point in the fixed catalyst bed and the warmest point in the fixed catalyst bed is kept at not more than 50 K.2. A process for providing a reactor comprising an activated fixed catalyst bed , in whicha) a fixed catalyst bed comprising monolithic shaped catalyst bodies or consisting of monolithic shaped catalyst bodies comprising at least one first metal selected from Ni, Fe, Co, Cu, Cr, Pt, Ag, Au and Pd, and comprising at least one second component selected from Al, Zn and Si, is introduced into a ...

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Номер записи: 21
28-01-2021 дата публикации

Method for Preparing Crosslinker Compound

Номер: US20210024451A1
Автор: Gicheul KIM, Ji Eun Kim, Ki Hyun Kim, Won Taeck Lim, Wonmun Choi, Yongjin Kim
Принадлежит: LG Chem Ltd

The present disclosure relates to a method for preparing a crosslinker compound in which a crosslinker compound capable of using for the production of a super absorbent polymer can be obtained in a higher yield by a simple manner. The crosslinker compound obtained by the above method can be used as a thermally decomposable crosslinker in the process of producing a super absorbent polymer.

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Номер записи: 22
04-02-2016 дата публикации

PROCESS AND SYSTEMS FOR OBTAINING 1,4-BUTANEDIOL FROM FERMENTATION BROTHS

Номер: US20160031778A1
Автор: Garikipati SVB Janardhan, Japs Michael, Sonico Ishmael M.
Принадлежит:

A process of purifying 1,4-butanediol (1,4-BDO) from a fermentation broth including separating solid materials, salts and water, and subjecting the resulting material to a two, three or four column distillation system, that can include a wiped film evaporator to produce a purified 1,4-butanediol product. 1. A process of purifying 1 ,4-butanediol (1 ,4-BDO) comprising:(a) subjecting a crude 1,4-BDO mixture to a first column distillation procedure to remove materials with a boiling point lower than 1,4-BDO from the crude 1,4-BDO mixture to produce a first 1,4-BDO-containing product stream; and(b) subjecting the first 1,4-BDO-containing product stream to a second column distillation procedure to remove materials with boiling points higher than 1,4-BDO as a first high-boilers stream, to produce a purified 1,4-BDO product, wherein the purified 1,4-BDO product is collected from a side-draw of the second column distillation procedure.2. The process of claim 1 , further comprising (c) subjecting the first high-boilers stream to wiped-film evaporation (WFE) to produce a first WFE distillate and subjecting the first WFE distillate to step (b).3. The process of further comprising (d) subjecting the first 1 claim 1 ,4-BDO-containing product stream claim 1 , prior to performing step (b) claim 1 , to an intermediate column distillation procedure to remove materials with boiling points higher than 1 claim 1 ,4-BDO as a second high-boilers stream.4. The process of claim 3 , further comprising (c) subjecting the second high-boilers stream to wiped-film evaporation (WFE) producing a second WFE distillate and subjecting the second WFE distillate to step (d).5. The process of claim 3 , further comprising (e) treating the first 1 claim 3 ,4-BDO-containing product stream with a hydrogenation reaction prior to performing step (b).6. The process of claim 1 , further comprising (f) treating the purified 1 claim 1 ,4-BDO product with a hydrogenation reaction.7. The process of wherein the ...

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Номер записи: 23
02-02-2017 дата публикации

Phosphonic acid catalyst in dehydrative cyclization of 5 and 6 carbon polyols with improved color and product accountability

Номер: US20170029434A1
Автор: Alexandra Sanborn, Erik Hagberg, Kenneth STENSRUD, Stephen Howard
Принадлежит: Archer Daniels Midland Co

A process for preparing cyclic dehydration products from sugar alcohols is described. The process involve using a mixed-acid catalyst reaction mixture containing a reducing acid, having a pKa of about 1.0-1.5, and at least a strong Brønsted acid or a Lewis acid, having a pKa≦0, or both acids in a solution to dehydrate and ring close said sugar alcohol. Synergistically, the mixed-acid catalysis can produce greater amounts of the desired product at similar levels of compositional accountability than either of the component acid catalysts acting alone.

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Номер записи: 24
01-02-2018 дата публикации

System And Method To Remove Organic Acid From A Rich MEG Stream By Stripping

Номер: US20180029963A1
Автор: Knight David John, Langley Steven
Принадлежит:

A system and method for removing acetic acid and other short chain fatty acids described as organic acid from a rich mono-ethylene glycol (“MEG”) solution does so by stripping the organic acid from the rich MEG solution by contacting the solution with a gas, the gas being nitrogen or a fuel gas such as methane; and stripping the organic acid from the gas by contacting the gas with a caustic solution such as a dilute sodium hydroxide solution. The stripping steps take place in respective stripping columns. A portion of the gas exiting the gas/organic acid stripping column can be recycled to the MEG/organic acid stripping column to reduce total gas usage. A portion of the waste stream exiting the gas/organic acid stripping column can be recycled back to the gas/organic acid stripping column to reduce the amount of caustic solution used as well as the amount of waste. 1. A method for removing organic acid from a MEG stream , the method comprising:stripping the organic acid from the MEG stream after a hydrate inhibition use of the MEG stream by contacting the MEG stream with a gaswherein the MEG stream after the contact with the gas is substantially free of the organic acid.2. A method according to further comprising:stripping the organic acid contained in the gas that contacted the MEG stream by contacting the gas with a caustic solutionwherein the gas after the contact with the caustic solution is substantially free of the organic acid.3. A method according to further comprising recycling a portion of the gas for use in the stripping of the organic acid from the MEG stream.4. A method according to further comprising recycling a portion of a waste stream from the stripping of the organic acid contained in the gas for use in the stripping of the organic acid contained in the gas.5. A method according to wherein the caustic solution is a sodium hydroxide solution comprising about 1% sodium hydroxide.6. A method according to further comprising adjusting claim 1 , when ...

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Номер записи: 25
31-01-2019 дата публикации

Aliphatic Materials and Uses Thereof in Heating and Cooling Applications

Номер: US20190033009A1
Автор: Bertin Paul
Принадлежит: ELEVANCE RENEWABLE SCIENCES, INC.

Aliphatic materials and their use in passive heating and cooling applications are generally disclosed. In some embodiments, dibasic acids and esters (diesters) thereof and their use in passive heating and cooling applications are disclosed. In some embodiments, Cdibasic acids and esters thereof are disclosed, including their use in passive heating and cooling applications. In some embodiments, various olefins, including alkenes and olefinic acids and esters, are disclosed, including their use in passive heating and cooling applications. 25-. (canceled)6. The method of claim 1 , wherein Xis —(CH)—.7. (canceled)8. (canceled)9. The method of claim 1 , wherein Ris an unbranched Calkyl claim 1 , which is optionally substituted one or more times by —OH.10. The method of claim 9 , wherein Ris methyl claim 9 , ethyl claim 9 , propyl claim 9 , butyl claim 9 , pentyl claim 9 , hexyl claim 9 , heptyl claim 9 , or octyl.11. The method of claim 9 , wherein Ris —CH—OH claim 9 , —CH—CH—OH claim 9 , —CH(—CH)—CH—OH claim 9 , or —CH—CH(—OH)—CH.12. The method of claim 1 , wherein Ris a branched Calkyl claim 1 , which is optionally substituted one or more times by —OH.13. The method of claim 12 , wherein Ris a branched Calkyl that comprises branching at the α-position.14. The method of claim 13 , wherein Ris isopropyl claim 13 , sec-butyl claim 13 , or tert-butyl.15. The method of claim 12 , wherein Ris a branched Calkyl that comprises branching at the β-position.16. The method of claim 15 , wherein Ris isobutyl or 2-ethylhexyl.17. The method of claim 12 , wherein Ris a branched Calkyl that comprises branching at the ψ-position.18. The method of claim 17 , wherein Ris isobutyl claim 17 , isoamyl claim 17 , neopentyl claim 17 , or 3 claim 17 ,5 claim 17 ,5-trimethylhexyl.1924-. (canceled)25. The method of claim 9 , wherein Ris an unbranched Calkyl claim 9 , which is optionally substituted one or more times by —OH.26. The method of claim 25 , wherein Ris methyl claim 25 , ethyl claim 25 ...

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Номер записи: 26
11-02-2016 дата публикации

MICROORGANISMS AND METHODS FOR PRODUCING BUTADIENE AND RELATED COMPOUNDS BY FORMATE ASSIMILATION

Номер: US20160040172A1
Автор: Andrae Stefan, Burgard Anthony P., LIS Ewa T., Osterhout Robin E., Pharkya Priti, RISSO Carla, Trawick John D.
Принадлежит:

Provided herein are non-naturally occurring microbial organisms having a FaldFP, a FAP and/or metabolic modifications which can further include a MMP, a MOP, a hydrogenase and/or a CODH. These microbial organisms can further include a butadiene, 13BDO, CrotOH, MVC or 3-buten-1-ol pathway. Additionally provided are methods of using such microbial organisms to produce butadiene, 13BDO, CrotOH, MVC or 3-buten-1-ol. 1. A non-naturally occurring microbial organism having a FaldFP and a FAP , wherein said organism comprises at least one exogenous nucleic acid encoding a FaldFP enzyme expressed in a sufficient amount to produce pyruvate , wherein said FaldFP comprises: 'wherein 1B is a 3-hexulose-6-phosphate synthase, wherein 1C is a 6P3HI, wherein 1D is a DHAS, wherein said organism comprises at least one exogenous nucleic acid encoding a FAP enzyme expressed in a sufficient amount to produce formaldehyde, pyruvate, or acetyl-CoA, wherein said FAP comprises a pathway selected from:', '(1) 1B and 1C; or (2) 1D,'} 'wherein 1E is a formate reductase, 1F is a formate ligase, a formate transferase, or a formate synthetase, wherein 1G is a formyl-CoA reductase, wherein 1H is a FTHFS, wherein 1I is a methenyltetrahydrofolate cyclohydrolase, wherein 1J is a MTHFDH, wherein 1K is a formaldehyde-forming enzyme or spontaneous, wherein 1L is a glycine cleavage system, wherein 1M is a serine hydroxymethyltransferase, wherein 1N is a serine deaminase, wherein 1O is a methylenetetrahydrofolate reductase, wherein 1P is an acetyl-CoA synthase.', '(3) 1E; (4) 1F, and 1G; (5) 1H, 1I, 1J, and 1K; (6) 1H, 1I, 1J, 1L, 1M, and 1N; (7) 1E, 1H, 1I, 1J, 1L, 1M, and 1N; (8) 1F, 1G, 1H, 1I, 1J, 1L, 1M, and 1N; (9) 1K, 1H, 1I, 1J, 1L, 1M, and 1N; and (10) 1H, 1I, 1J, 1O, and 1P,'}2. The non-naturally occurring microbial organism of claim 1 , wherein said microbial organism comprises one claim 1 , two claim 1 , three claim 1 , four claim 1 , five claim 1 , six claim 1 , seven claim 1 , or eight ...

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Номер записи: 27
08-02-2018 дата публикации

Process Scheme To Improve Divalent Metal Salts Removal From Mono Ethylene Glycol (MEG)

Номер: US20180037527A1
Автор: Luis Eduardo Caires Fernandez
Принадлежит: Cameron International Corp

A MEG reclamation process includes the step of increasing above 2,000 ppm the divalent metal salts concentration of a rich (wet) MEG feed stream flowing into a precipitator. The increasing step includes routing a salts-saturated MEG slipstream from the flash separator it to the precipitator. The slipstream may be mixed with a fresh water feed stream, a portion of the rich MEG feed stream, or some combination of the two. The rich MEG feed stream also may be split into two streams, with a portion of the stream being heated and routed to the flash separator and the other portion being combined as above with the removed slipstream. The process can be performed on the slipstream after dilution and prior to entering the precipitator or after being loaded into the precipitator. Removal of the insoluble salts may be done in either a batch or continuous mode.

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Номер записи: 28
24-02-2022 дата публикации

Methods for Preparing Diol

Номер: US20220055974A1
Автор: Liu Jing, Prakash Indra, Qi Hongbin, Ren Haiyu, SHI YU
Принадлежит:

Provided is a method for preparing a diol. In the method, a saccharide and hydrogen as raw materials are contacted with a catalyst in water to prepare the diol. The employed catalyst is a composite catalyst comprised of a main catalyst and a cocatalyst, wherein the main catalyst is a water-insoluble acid-resistant alloy; and the cocatalyst is a soluble tungstate and/or soluble tungsten compound. The method uses an acid-resistant, inexpensive and stable alloy needless of a support as a main catalyst, and can guarantee a high yield of the diol in the case where the production cost is relatively low. 1. A method for preparing a diol , characterized by:(a) adding an unsupported main catalyst comprising nickel, one or more rare earth elements, tin and aluminium, and optionally i) tungsten, ii) tungsten and molybdenum, or iii) tungsten, molybdenum and boron or phosphorus to a slurry bed reactor;(b) increasing the reaction system pressure to 5-12 MPa and the reaction temperature to 150-260° C.;(c) adding a soluble tungstic acid salt cocatalyst, hydrogen and a sugar to the slurry bed reactor, wherein the sugar and cocatalyst are fed continuously into the slurry bed reactor in the form of an aqueous sugar solution having a sugar concentration from 20-60 wt % and further comprising the soluble tungstic acid salt cocatalyst to provide gas and a liquid comprising a diol;(d) continuously passing the gas and reaction liquid out of the reactor through a filter to intercept catalyst and(e) separating the diol from the gas and reaction liquid.2. The method for preparing a diol as claimed in claim 1 , characterized in that the diol is ethylene glycol.3. The method for preparing a diol as claimed in claim 2 , characterized in that the reaction system pH is 1-7; more preferably claim 2 , the reaction system pH is 3-6.4. The method for preparing a diol as claimed in claim 1 , characterized in that the sugar is selected from one or more of five-carbon monosaccharides claim 1 , ...

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Номер записи: 29
07-02-2019 дата публикации

PROCESS FOR THE PRODUCTION OF ALKYLENE GLYCOLS

Номер: US20190039979A1
Автор: DE VLIEGER Dionysius Jacobus Maria, HUIZENGA Pieter, VAN DER HEIDE Evert
Принадлежит:

The invention provides a process for the production of alkylene glycols, said process comprising providing a feed comprising at least 10 wt % of lignocellulose and/or one or more saccharides, on the basis of the overall feed, in water to a reactor; also providing a feed comprising one or more hydrogen-donating organic solvent species to the reactor; contacting the lignocellulose and/or one or more saccharides in the reactor with a retro-aldol catalyst composition at a temperature in the range of from at least 160 to at most 270° C., wherein the combined solvent system within the reactor comprises in the range of from at least 5 to at most 95 wt % of one or more hydrogen-donating organic solvent species and in the range of from at least 5 to at most 95 wt % of water. 1. A process for the production of alkylene glycols , said process comprising providing a feed comprising at least 10 wt % of lignocellulose and/or one or more saccharides , on the basis of the overall feed , in water to a reactor; also providing a feed comprising one or more hydrogen-donating organic solvent species to the reactor; contacting the lignocellulose and/or one or more saccharides in the reactor with a retro-aldol catalyst composition at a temperature in the range of from at least 160 to at most 270° C. , wherein the combined solvent system within the reactor comprises in the range of from at least 5 to at most 95 wt % of one or more hydrogen-donating organic solvent species and in the range of from at least 5 to at most 95 wt % of water.2. The process according to claim 1 , wherein the hydrogen-donating organic solvent species is selected from the group consisting of secondary alcohols claim 1 , glycols claim 1 , hydroquinone claim 1 , formic acid and sugar alcohols.3. The process as claimed in claim 2 , wherein the hydrogen-donating organic solvent species is selected from isopropyl alcohol claim 2 , glycerol claim 2 , erythritol claim 2 , threitol claim 2 , sorbitol claim 2 , xylitol claim ...

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Номер записи: 30
07-02-2019 дата публикации

PROCESSES TO CREATE MULTIPLE VALUE STREAMS FROM BIOMASS SOURCES

Номер: US20190039981A1
Автор: ALLEN Lloyd, Arato Claudio, BRIX Terry, CLARKE Peter Andrew, Davies Joshua, GENE Bryan, Kirby Mark, LEE Quak Foo, MCKEAN William, MUNJAPARA Ankit, Norton Clive Richard, STEIN Stuart A., Stock Greg, Sugden David
Принадлежит: Intercontinental Great Brands LLC

Use of diverse biomass feedstock in a process for the recovery of target C5 and C6 alditols and target glycols via staged hydrogenation and hydrogenolysis processes is disclosed. Particular alditols of interest include, but are not limited to, xylitol and sorbitol. Various embodiments of the present invention synergistically improve overall recovery of target alditols and/or glycols from a mixed C5/C6 sugar stream without needlessly driving total recovery of the individual target alditols and/or glycols. The result is a highly efficient, low complexity process having enhanced production flexibility, reduced waste and greater overall yield than conventional processes directed to alditol or glycol production. 1. A process , comprising:selecting a target alditol or a target blend of alditols,hydrogenating continuously a mixed C5/C6 monomer sugar stream to form a mixed C5/C6 alditol stream;isolating the target alditol or target blend of alditols from the mixed C5/C6 alditol stream to leave a residual mixed C5/C6 alditol stream;continuous hydrogenolysis of the residual mixed C5/C6 alditol stream to form a mixed C2-C4 glycol stream; andisolating a target glycol or target blend of glycols from the mixed C2-C4 glycol stream;wherein at least 10% of the overall target product yield is either target alditol/target blend of alditols or target glycol/target blend of glycols.23.-. (canceled)4. The process of claim 1 , wherein the monomer sugar stream or the mixed C5/C6 monomer sugar stream comprises greater than or equal to 60% C5 monomer sugar based on the combined total of C5 and C6 monomer sugars claim 1 , specifically greater than or equal to 65% C5 monomer sugar claim 1 , and more specifically greater than or equal to 70% C5 monomer sugar; orwherein the monomer sugar stream or the mixed C5/C6 monomer sugar stream comprises greater than or equal to 60% C6 monomer sugar based on the combined total of C5 and C6 monomer sugars, specifically greater than or equal to 65% C6 ...

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Номер записи: 31
06-02-2020 дата публикации

WATER-SOLUBLE UNIT DOSE ARTICLES MADE FROM A COMBINATION OF DIFFERENT FILMS

Номер: US20200040288A1
Автор: COURCHAY Florence Catherine, Friedrich Steven G., KEULEERS Robby Renilde Francois, LABEQUE Regine, Lee David M., Nii Shinsuke, Renmans Marc Rene Bert, Souter Philip Frank, Yeung Lee K.
Принадлежит:

The present disclosure relates to pouches made from a combination of chemically different water-soluble films and optionally containing a composition (e.g. a household care composition or non-household care composition) that is at least partially enclosed by the water-soluble films in at least one compartment. 153-. (canceled)54. A water-soluble unit dose article comprising at least one sealed compartment optionally comprising at least one composition contained in the article , the water-soluble unit dose article comprisinga first water soluble film comprising a PVOH polymer comprising a first anionic content;and a second water soluble film comprising a PVOH polymer comprising a second anionic content;wherein the first anionic content is in a range of about 0.5 mol % to about 10 mol % of total PVOH polymer in the first water soluble film and the second anionic content is in a range of about 0 mol % to about 5 mol % of total PVOH polymer in the second water soluble film, and the difference between the first anionic content and second anionic content is about 0.05 mol % to about 4 mol %, wherein the anionic content of each film is the molar percentage of anionic monomer units present in the total PVOH polymer of the film, and wherein the first water-soluble film is chemically different from the second water soluble film with respect to the anionic content of the PVOH polymers of the films;wherein the first film is sealed to the second film to form the at least one sealed compartment;provided that when the composition is a fabric care or household care composition and a film comprises a blend of a polyvinyl alcohol homopolymer resin and an anionic polyvinyl alcohol copolymer resin, then both then first water soluble film and the second water soluble film comprise blends that include 65 wt. % or greater of an anionic polyvinyl alcohol copolymer resin, based on the total weight of polyvinyl alcohol resins in the blend; andprovided that when the composition is a fabric ...

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Номер записи: 32
01-05-2014 дата публикации

METHODS FOR PRODUCTION AND PROCESSING OF A GLYCOL REACTION PRODUCT OBTAINED FROM HYDROTHERMAL DIGESTION OF CELLULOSIC BIOMASS SOLIDS

Номер: US20140121420A1
Автор: JOHNSON Kimberly Ann, POWELL Joseph Broun
Принадлежит: SHELL OIL COMPANY

Hydrothermal digestion of cellulosic biomass solids may be conducted such that a glycol reaction product is formed for subsequent processing. Processing of a glycol reaction product may include a drying operation conducted prior to condensation of the glycol reaction product into higher molecular weight compounds. Methods for digesting cellulosic biomass solids to form a glycol reaction product can comprise: providing cellulosic biomass solids and a slurry catalyst in a hydrothermal digestion unit, the slurry catalyst being capable of activating molecular hydrogen; heating the cellulosic biomass solids in the hydrothermal digestion unit in the presence of the slurry catalyst, a digestion solvent, and molecular hydrogen, thereby forming a liquor phase comprising soluble carbohydrates; and performing a first catalytic reduction reaction on the soluble carbohydrates within the hydrothermal digestion unit, thereby at least partially converting the soluble carbohydrates into a reaction product comprising a glycol. 1. A method comprising:providing cellulosic biomass solids;converting the cellulosic biomass solids into a reaction product comprising a glycol; andat least partially drying the reaction product, thereby forming a dried reaction product comprising a dried glycol.2. The method of claim 1 , wherein at least about 5 percent by weight of the cellulosic biomass solids are converted into the glycol.3. The method of claim 1 , wherein the dried glycol comprises about 35 wt. % or less water.4. The method of claim 1 , further comprising:separating the dried glycol from the dried reaction product.5. The method of claim 1 , further comprising:exposing the dried glycol or a product formed therefrom to a condensation catalyst; andconverting the dried glycol into a higher molecular weight compound using the condensation catalyst.6. The method of claim 5 , wherein the condensation catalyst comprises a zeolite.7. The method of claim 1 , wherein converting the cellulosic biomass ...

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Номер записи: 33
16-02-2017 дата публикации

Ruthenium complex, method for producing same, and use of same

Номер: US20170044196A1
Автор: Hideki Nara, Osamu Ogata, Yuji Nakayama
Принадлежит: Takasago International Corp

The present invention provides a novel ruthenium complex that is easy to produce and handle and that can be supplied relatively inexpensively, a method for producing this ruthenium complex, a method for producing alcohols and the like using this ruthenium complex as a catalyst, a method for producing carbonyl compounds using this ruthenium complex as a catalyst, and a method for producing N-alkylamine compounds using this ruthenium complex as a catalyst. The present invention pertains to a ruthenium complex represented by general formula (1) RuX 1 X 2 (PNP) (NHC) m (Solv) n (1) (in general formula (1), X 1 and X 2 each independently represent a monovalent anionic monodentate ligand; PNP represents a tridentate aminodiphosphine ligand, NHC represents an N-heterocyclic carbene derived from a nitrogen-containing heterocyclic ring, and Solv represents a coordinating solvent; and m represents an integer from 1 to 3, n represents an integer from 0 to 2, and 1≦m+n≦3.), a method for producing the same, a catalyst including the same, and methods for producing various organic compounds using this catalyst.

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Номер записи: 34
15-02-2018 дата публикации

SYSTEMS AND METHODS RELATED TO THE PRODUCTION OF ETHYLENE OXIDE, ETHYLENE GLYCOL, AND/OR ETHANOLAMINES

Номер: US20180044308A1
Автор: Ahmed Labeeb Chaudhary, Al-Hammad Ali, Al-Jaloud Abdullah Turki, Al-Khudeer Saud, Al-Qahtani Thabet, Al-Shammari Talal, Bashir Mubarik Ali, Karim Khalid, Khurram Shehzada, Nawaz Zeeshan
Принадлежит:

Disclosed herein is a method comprising the steps of: a) producing a hydrocarbon stream from syngas via a Fischer-Tropsch reaction, wherein the hydrocarbon stream comprises a first C2 hydrocarbon stream comprising ethane and a first ethylene product; b) separating at least a portion of the first C2 hydrocarbon stream from the hydrocarbon stream; c) separating at least a portion of the first ethylene product from the first C2 hydrocarbon stream, thereby producing a second C2 hydrocarbon stream; d) converting at least a portion of the ethane in the second C2 hydrocarbon stream to a second ethylene product; and e) producing ethylene oxide from at least a portion of the second ethylene product. 1. A method comprising the steps of:producing a hydrocarbon stream from syngas via a Fischer-Tropsch reaction, wherein the hydrocarbon stream comprises a first C2 hydrocarbon stream comprising ethane and a first ethylene product;separating at least a portion of the first C2 hydrocarbon stream from the hydrocarbon stream;separating at least a portion of the first ethylene product from the first C2 hydrocarbon stream, thereby producing a second C2 hydrocarbon stream;converting at least a portion of the ethane in the second C2 hydrocarbon stream to a second ethylene product; andproducing ethylene oxide from at least a portion of the second ethylene product.2. The method of claim 1 , wherein the first C2 hydrocarbon stream comprises from about 30 wt % to about 70 wt % of ethane and from about 70 wt % to about 30 wt % of the first ethylene product.3. The method of wherein the second C2 hydrocarbon stream comprises at least about 80 wt % of ethane.4. The method of claim 1 , wherein the hydrocarbon stream further comprises from about 30 wt % to about 70 wt % of C3-C10 hydrocarbons.5. The method of claim 1 , wherein the method further comprises the step of producing ethylene glycol from at least a portion of the ethylene oxide.6. The method of claim 1 , wherein the method further ...

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Номер записи: 35
19-02-2015 дата публикации

DIAGNOSTIC AGENT AND DIAGNOSTIC METHOD FOR IRRITABLE BOWEL SYNDROME INDUCED BY ABNORMAL PROLIFERATION OF ENTEROBACTERIA

Номер: US20150050744A1
Автор: Kajiwara Masahiro, Nonomura Hideji, Urita Yoshihisa
Принадлежит:

[Problem to be Solved] 1. A diagnostic agent for detecting abnormal proliferation of enterobacteria in a patient suspected to be suffering from an irritable bowel syndrome , the diagnostic agent comprising a compound that is decomposed by enterobacteria and is labeled with a carbon isotope C.2. (canceled)3. The diagnostic agent according to claim 1 , wherein the diagnostic agent is an oral pharmaceutical agent.4. The diagnostic agent according to claim 1 , wherein the diagnostic agent is used in a breath test for measuring COexcreted in exhaled breath after the administration.5. The diagnostic agent according to claim 1 , wherein the compound is selected from the group consisting of monosaccharides claim 1 , disaccharides claim 1 , oligosaccharides claim 1 , celluloses claim 1 , organic acids claim 1 , and salts thereof.6. The diagnostic agent according to claim 1 , wherein the compound is a monosaccharide selected from the group consisting of sorbitol claim 1 , mannose claim 1 , mannitol claim 1 , rhamnose claim 1 , arabinose claim 1 , fucose claim 1 , and xylitol; a disaccharide selected from the group consisting of lactulose claim 1 , maltose claim 1 , and lactose; an oligosaccharide selected from the group consisting of soybean oligosaccharide and isomaltooligosaccharide; carmellose (carboxymethyl cellulose); or an organic acid selected from the group consisting of sodium alginate claim 1 , magnesium citrate claim 1 , and 5-aminosalicylic acid.7. The diagnostic agent according to claim 5 , wherein the compound is a saccharide labeled with a carbon isotope at the 1-position.8. The diagnostic agent according to claim 1 , wherein the compound has a carbon isotope C substituted for all carbon atoms of the molecule (uniform material).9. (canceled)10. (canceled)11. A method for determining whether there is abnormal proliferation of enterobacteria claim 1 , the method comprising:{'sup': 13', '13', '12', '13', '12, 'sub': 2', '2', '2', '2', '2, 'claim-ref': {'@idref': ' ...

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Номер записи: 36
03-03-2022 дата публикации

METHOD FOR PRODUCING 1,2-ALKANE DIOLS IN A SOLID DOSAGE FORM

Номер: US20220064089A1
Автор: SIEWERT Jürgen, STEPHAN Torsten
Принадлежит:

A process is proposed for producing 1,2-alkanediols in a solid dosing form, comprising or consisting of the following steps: 1. A process for producing 1 ,2-alkanediols in a solid dosing form , comprising the following steps:(a) providing a melt of at least one 1,2-alkanediol;(b) cooling the melt from step (a) to a temperature below the melting point of the 1,2-alkanediol or of the 1,2-alkanediol mixture to obtain a prescratched melt consisting of a supercooled 1,2-alkanediol or a supercooled 1,2-alkanediol mixture having a content of 1,2-alkanediol seed crystals;(c) contacting the mixture from step (b) with a cooled surface to obtain 1,2-alkanediols or 1,2-alkanediol mixtures in crystalline form.2. The process of claim 1 , wherein the at least one alkanediol is selected from 1 claim 1 ,2-alkanediols having 8 to 14 carbon atoms.3. The process of wherein the at least one 1 claim 1 ,2-alkanediol is selected from the group consisting of octane-1 claim 1 ,2-diol claim 1 , decane-1 claim 1 ,2-diol claim 1 , dodecane-1 claim 1 ,2-diol claim 1 , and tetradecane-1 claim 1 ,2-diol.4. The process of claim 1 , wherein the at least one 1 claim 1 ,2-alkanediol is selected from technical grade 1 claim 1 ,2-alkanediols having a 1 claim 1 ,2-alkanediol content of at least 92% by weight.5. The process of claim 1 , wherein the 1 claim 1 ,2-alkanediols or 1 claim 1 ,2-alkanediol mixtures in crystalline form produced in step (c) are 1 claim 1 ,2-alkanediols having a smooth or near-smooth surface.6. The process of claim 1 , wherein the melts are stirred while cooled in step (b).7. The process of claim 1 , where in step (b) the melts are cooled until the proportion of seed crystals in the prescratched melt is at least 1% by weight.8. The process of claim 1 , wherein additional seed crystals are added to the prescratched melt of step (b).9. The process of claim 1 , wherein the prescratched melt of step (b) is cooled with stirring until it has a torque/viscosity within a range of from ...

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Номер записи: 37
25-02-2016 дата публикации

PRODUCTION OF PARTIALLY REFINED WASTE GLYCEROL

Номер: US20160052847A1
Автор: Ko Myong K., Li Simon, Liao Perry Y., Sanchez-Riera Fernando A.
Принадлежит: REG Life Sciences, LLC

The disclosure relates to a novel glycerol purification process that produces partially refined waste glycerol for a variety of industrial applications. The disclosure encompasses a salt-containing partially refined glycerol composition that is suitable as a fermentation grade glycerol. 1. A process of producing partially refined waste glycerol by refining crude glycerol containing organic impurities , said process comprising:deoiling using a hydrophobic solvent to extract organic impurities;dewatering by drying at an elevated temperature; anddesalting using a polar solvent to precipitate salt.2. A process of producing partially refined waste glycerol by refining crude glycerol containing organic impurities , said process comprising:subjecting crude glycerol to a hydrophobic solvent to produce a mixture of crude glycerol and hydrophobic solvent; andseparating the mixture of crude glycerol and hydrophobic solvent to produce a deoiled (DO) glycerol and a phase containing hydrophobic solvent and organic impurities.3. The process of claim 2 , further comprising the step of drying said DO glycerol to produce a deoiled and dewatered (DOW) glycerol.4. The process of claim 3 , further comprising the steps of:subjecting a polar solvent to said DOW glycerol to produce a mixture of polar solvent and DOW glycerol and precipitating a salt from the mixture of polar solvent and DOW glycerol; andseparating the mixture of polar solvent and DOW glycerol into a light phase containing a deoiled, dewatered and desalted (DOWS) glycerol and the polar solvent and a heavy phase containing the salt.5. The process of claim 4 , further comprising the step of removing the polar solvent from the light phase to produce a purified DOWS glycerol.6. The process of claim 4 , further comprising the step of partially evaporating the DOW glycerol before subjecting it to the polar solvent.7. The process of claim 2 , further comprising the steps of:subjecting a polar solvent to said DO glycerol to produce ...

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Номер записи: 38
08-05-2014 дата публикации

Microorganisms and methods for production of specific length fatty alcohols and related compounds

Номер: US20140127765A1
Автор: Anthony P. Burgard, Robin E. Osterhout
Принадлежит: Genomatica Inc

The invention provides non-naturally occurring microbial organisms containing a fatty alcohol, fatty aldehyde or fatty acid pathway, wherein the microbial organisms selectively produce a fatty alcohol, fatty aldehyde or fatty acid of a specified length. Also provided are non-naturally occurring microbial organisms having a fatty alcohol, fatty aldehyde or fatty acid pathway, wherein the microbial organisms further include an acetyl-CoA pathway. In some aspects, the microbial organisms of the invention have select gene disruptions or enzyme attenuations that increase production of fatty alcohols, fatty aldehydes or fatty acids. The invention additionally provides methods of using the above microbial organisms to produce a fatty alcohol, a fatty aldehyde or a fatty acid.

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Номер записи: 39
22-02-2018 дата публикации

OPEN-FLASK HYDROBORATION AND THE USE THEREOF

Номер: US20180050972A1
Автор: Drolet Michael Patrick, Kulkarni Ameya Sanjay, Ramachandran P Veeraraghavan
Принадлежит: PURDUE RESEARCH FOUNDATION

The present disclosure generally relates to a process for hydroboration of an alkene or alkyne using ammonia borane (AB). In particular, the present invention relates to hydroboration of an alkene or alkyne in the presence of air or moisture, and a clean process for facile preparation of an alcohol by oxidizing the organoborane so formed with hydrogen peroxide. The products, including aminodialkylboranes, ammonia trialkylborane complexes, as well as various alcohols so prepared, are within the scope of this disclosure. 1. A process for hydroboration of an alkene or alkyne , comprising the steps ofa. preparing a solution of an ammonia borane (AB);b. adding an alkene or alkyne to said AB solution; andc. refluxing with heating and stirring to afford an organoborane, wherein the effectiveness of this process is not affected by the presence of air or moisture.2. The process of claim 1 , wherein the solution of an ammonia borane is prepared using an ethereal solvent.3. The process of claim 2 , wherein said ethereal solvent is THF (tetrahydrofuran).4. The process of claim 1 , wherein the solution of an ammonia borane in THF has a concentration of about 0.5˜2 M (moles/liter).5. The process of claim 1 , wherein said refluxing is performed at about 90° C.6. The process of claim 1 , wherein said alkene or alkyne is part of an aromatic molecule claim 1 , an aliphatic molecule claim 1 , or a combination thereof.7. The process of claim 1 , wherein said alkene or alkyne is part of a cyclic structure claim 1 , a linear structure claim 1 , or a combination thereof.8. The process of claim 1 , wherein the molar ratio of said AB to said alkene or alkyne ranges from about 2 to about 0.2.9. An aminodialkylborane or ammonia-trialkylborane complex prepared according to the process ofa. preparing a solution of an ammonia borane (AB);b. adding an alkene or alkyne to said AB solution; andc. refluxing with heating and stirring to afford an organoborane, wherein the effectiveness of this ...

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Номер записи: 40
22-02-2018 дата публикации

ALKALINE PH-MODIFIED EDIBLE CASEIN-BASED FILMS AND COATINGS, AND METHOD FOR THE MAKING THEREOF

Номер: US20180051062A1
Автор: BONNAILLIE LAETITIA, Tomasula Peggy M.
Принадлежит:

Improved casein-based films are produced by adjusting the pH of a film-production suspension. The film-production suspension may contain a casein source, a plasticizer, and optionally a strengthening additive. The adjustment of the pH may be accomplished by the addition of an alkaline additive, such as a base, to achieve a desired pH value. The improved casein-based films have improved physical properties as compared to those produced without a pH-adjusted film-production suspension at least in part due to the chemical and structural changes imparted by the change in pH. 1: A casein-based film , comprising:a casein source;a plasticizer; andan alkaline additive,wherein the film has a melting point temperature at 50% relative humidity of at least 60° C.2: The casein-based film of claim 1 , wherein the film has a storage modulus claim 1 , G′ claim 1 , at 50% relative humidity and 60° C. claim 1 , of at least 150 MPa.3: The casein-based film of claim 1 , wherein the casein source is one of a caseinate claim 1 , a fluid or dried milk product claim 1 , milk protein concentrate claim 1 , micellar casein concentrate claim 1 , and a mixture thereof.4: The casein-based film of claim 1 , wherein the plasticizer is one of glycerol claim 1 , sorbitol claim 1 , propylene glycol claim 1 , polypropylene glycol claim 1 , sucrose claim 1 , and a mixture thereof.5: The casein-based film of claim 1 , wherein the amounts of the casein source and the plasticizer are present in a ratio of casein source:plasticizer being 99:1 to 1:1.6: The casein-based film of claim 1 , further comprising a strengthening additive.7: The casein-based film of claim 6 , wherein the strengthening additive is one of a pectin claim 6 , a polysaccharide claim 6 , a pullulan-microbial polysaccharide claim 6 , a dextrin claim 6 , an oligosaccharides claim 6 , a monosaccharide claim 6 , a disaccharide claim 6 , high fructose corn syrup claim 6 , cellulose claim 6 , hemi-cellulose claim 6 , a gum or the constitutive ...

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Номер записи: 41
20-02-2020 дата публикации

Porous shaped metal-carbon products

Номер: US20200055029A1
Автор: Alfred Hagemeyer, Elif Ispir GÜRBÜZ, Eric L. Dias, Guang Zhu, James A.W. Shoemaker, Valery Sokolovskii
Принадлежит: Archer Daniels Midland Co

The present invention provides a porous metal-containing carbon-based material that is stable at high temperatures under aqueous conditions. The porous metal-containing carbon-based materials are particularly useful in catalytic applications. Also provided, are methods for making and using porous shaped metal-carbon products prepared from these materials.

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Номер записи: 42
04-03-2021 дата публикации

NOBLE METAL-TRANSITION METAL COMPLEX CATALYST SUPPORTED ON CARBON-COATED SILICA-ALUMINA SUPPORT, AND PREPARATION METHOD THEREFOR

Номер: US20210061742A1
Автор: Jeon Bong Sik, KIM Jeong Kwon, Myeong Wan Jae, YOOK Sun Woo
Принадлежит: HANWHA SOLUTIONS CORPORATION

Provided are a noble metal-transition metal complex catalyst supported on a carbon-coated silica-alumina support and a preparation method therefor, the catalyst being capable of obtaining a fast reaction rate and catalyst stability, as compared to a conventional catalyst, when cyclohexane dimethanol (CHDM) production is carried out by a cyclohexane dicarboxylic acid (CHDA) hydrogenation reaction in an aqueous solution by using a carbon-coated supported catalyst. 1. A noble metal-transition metal complex catalyst supported on a carbon-coated silica-alumina carrier , wherein{'sub': 2', '3', '2, '40 parts by weight to 95 parts by weight of alumina (AlO) and 5 parts by weight to 60 parts by weight of silica (SiO) are included based on 100 parts by weight of the entire carrier; and'}1 part by weight to 20 parts by weight of the noble metal and the transition metal are included based on 100 parts by weight of the carbon-coated silica-alumina carrier.2. The noble metal-transition metal complex catalyst of claim 1 , wherein the noble metal includes one or more selected from the group consisting of palladium (Pd) claim 1 , rhodium (Rh) claim 1 , ruthenium (Ru) claim 1 , and platinum (Pt).3. The noble metal-transition metal complex catalyst of claim 1 , wherein an amount of the noble metal is in a range of 1 part by weight to 10 parts by weight based on 100 parts by weight of the carrier.4. The noble metal-transition metal complex catalyst of claim 1 , wherein the transition metal includes one or more selected from the group consisting of tin (Sn) claim 1 , iron (Fe) claim 1 , rhenium (Re) claim 1 , and gallium (Ga).5. The noble metal-transition metal complex catalyst of claim 1 , wherein an amount of the transition metal is in a range of 1 part by weight to 10 parts by weight based on 100 parts by weight of the carrier.6. The noble metal-transition metal complex catalyst of claim 1 , wherein a noble metal precursor and a transition metal precursor are supported on the ...

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Номер записи: 43
28-02-2019 дата публикации

Process for the separation of glycols

Номер: US20190062244A1
Автор: Carmelo PEREZ GOLF, Evert Van Der Heide, Kai Jürgen FISCHER, Pieter HUIZENGA
Принадлежит: Shell Oil Co

A process for the production of high purity mono-ethylene glycol (MEG) from a product stream of a saccharide hydrogenolysis process. The process having the steps of: (i) removing solvent from the product stream to provide a solvent-lean product stream; (ii) subjecting the solvent-lean product stream to distillation to provide a bottoms stream comprising high boiling by-products and a top stream comprising a mixture comprising MEG and 1,2-butanediol (1,2-BDO); (iii) providing said mixture having MEG and 1,2-BDO as a feed to a distillation column; (iv) providing a feed comprising an extractant of C3 to C6 alcohols and mixtures thereof to the distillation column above the mixture comprising MEG and 1,2-BDO; (v) removing a stream comprising MEG and the extractant as a bottoms stream from the distillation column; and (vi) subjecting the stream comprising MEG and the extractant to distillation to provide a top stream comprising high purity MEG.

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Номер записи: 44
08-03-2018 дата публикации

Process and systems for obtaining 1,4-butanediol from fermentation broths

Номер: US20180065907A1
Автор: Ishmael M. SONICO, Michael Japs, Svb Janardhan GARIKIPATI
Принадлежит: Genomatica Inc

A process of purifying 1,4-butanediol (1,4-BDO) from a fermentation broth including separating solid materials, salts and water, and subjecting the resulting material to a two, three or four column distillation system, that can include a wiped film evaporator to produce a purified 1,4-butanediol.

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Номер записи: 45
11-03-2021 дата публикации

PREPARATION METHOD FOR CYCLOHEXANE DIMETHANOL HAVING HIGH TRANS CONTENT AND CYCLOHEXANE DIMETHANOL PREPARED THEREBY

Номер: US20210070682A1
Автор: Han Joo Hee, KIM Eun Jeong, KIM Ki Don, Lee Jong Kwon, Nam Ho Seong
Принадлежит: HANWHA SOLUTIONS CORPORATION

Provided is a preparation method for a cyclohexane dimethanol (CHDM), which can have a high trans content through particular conditions, additive addition, or reactant addition, which is controlled in a cyclohexane dicarboxylic acid (CHDA) hydrogenation reaction, and a cyclohexane dimethanol prepared thereby. 1. A method for preparing a cyclohexane dimethanol (CHDM) by performing a hydrogenation reaction of a catalyst and a cyclohexane dicarboxylic acid (CHDA) , wherein a weight ratio of the catalyst to the cyclohexane dicarboxylic acid (CHDA) is 1:1 to 1:5.2. The method of claim 1 , wherein at least one selected from a homogeneous additive and a heterogeneous additive is further included in the hydrogenation reaction.3. The method of claim 2 , wherein the homogeneous additive includes at least one selected from the group consisting of ammonium bicarbonate (NHHCO) claim 2 , sodium hydroxide (NaOH) claim 2 , potassium carbonate (KCO) claim 2 , and sodium borohydride (NaBH) claim 2 , and the heterogeneous additive includes at least one selected from the group consisting of zirconia claim 2 , titania claim 2 , ceria claim 2 , silica claim 2 , and magnesia.4. The method of claim 2 , wherein a weight ratio of the homogeneous additive to the catalyst is 1:0.05 to 1:1.5. The method of claim 2 , wherein a weight ratio of the heterogeneous additive to the catalyst is 1:0.5 to 1:3.6. The method of claim 1 , wherein the hydrogenation reaction of the cyclohexane dicarboxylic acid (CHDA) is performed in a temperature range of 200° C. to 280° C.7. The method of claim 1 , wherein the hydrogenation reaction of the cyclohexane dicarboxylic acid (CHDA) is performed in a pressure range of 50 bar to 150 bar.8. The method of claim 1 , wherein the hydrogenation reaction of the cyclohexane dicarboxylic acid (CHDA) is performed for 1 hour to 8 hours.9. The method of claim 1 , wherein the cyclohexane dicarboxylic acid (CHDA) uses a reactant selected from a cis form claim 1 , a trans form ...

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Номер записи: 46
24-03-2022 дата публикации

CONTINUOUS PROCESSES FOR THE SELECTIVE CONVERSION OF ALDOHEXOSE-YIELDING CARBOHYDRATE TO ETHYLENE GLYCOL USING LOW CONCENTRATIONS OF RETRO-ALDOL CATALYST

Номер: US20220089514A1
Автор: Albin Brooke, Bradford Michael, Bunning Donald, Kapicak Louis A., Nunley Mark, Schreck David James
Принадлежит:

Retro-aldol processes are disclosed that use very low concentrations of retro-aldol catalyst in combination with hydrogenation catalyst of certain activities, sizes and spatial dispersions to obtain the high selectivities to ethylene glycol. 1. A continuous , catalytic process for producing ethylene glycol from an aldose-yielding carbohydrate-containing feed , comprising: (i) the heterogeneous hydrogenation catalyst has a maximum particle dimension of less than about 100 microns, and', '(ii) the hydrogenation catalyst is dispersed in the liquid medium in an amount of less than about 100 grams per liter thereby providing a spatial relationship among catalytically active hydrogenation sites in the liquid medium;, '(a) continuously or intermittently supplying the feed to a reaction zone containing a liquid medium having therein heterogeneous, nickel-containing hydrogenation catalyst, wherein the feed is supplied at a rate of at least about 50 grams per hour of carbohydrate per liter of liquid medium, and wherein said liquid medium is at catalytic conversion conditions including the presence of dissolved hydrogen, a temperature of at least about 235° C., a pH greater than 3 and a residence time sufficient to react at least 99 mass percent of the aldose-yielding carbohydrate, wherein(b) continuously or intermittently supplying to the reaction zone homogeneous, tungsten-containing retro-aldol catalyst the concentration of solubilized tungsten compounds, calculated as tungsten atoms, in the liquid medium in the reactor is from about 200 to 1500 milligrams per liter, wherein the relative amounts of hydrogenation catalyst and retro-aldol catalyst are sufficient to provide, under the catalytic conversion conditions, a cumulative conversion efficiency of the aldose-containing carbohydrate to ethylene glycol of at least 75 percent for a duration of 100 hours; and(c) continuously or intermittently withdrawing from the reaction zone a raw product stream containing ethylene glycol ...

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Номер записи: 47
24-03-2022 дата публикации

Continuous processes for the selective conversion of aldohexose-yielding carbohydrate to ethylene glycol using low concentrations of retro-aldol catalyst

Номер: US20220089515A1
Автор: Brooke ALBIN, David James Schreck, Donald Bunning, Louis A. Kapicak, Mark Nunley, Michael Bradford
Принадлежит: TEn Process Technology Inc, TEn Stone & Webster Process Technology Inc

Retro-aldol processes are disclosed that use very low concentrations of retro-aldol catalyst in combination with hydrogenation catalyst of certain activities, sizes and spatial dispersions to obtain the high selectivities to ethylene glycol.

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Номер записи: 48
16-03-2017 дата публикации

CYCLOALKYL-HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES

Номер: US20170073286A1
Автор: Dasseux Jean-Louis H., Oniciu Carmen D.
Принадлежит:

The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents. 2. The compound of claim 1 , wherein each occurrence of Yand Yis independently OH claim 1 , COOR claim 1 , or COOH.3. The compound of claim 1 , wherein m is 0.4. The compound of claim 1 , wherein m is 1.5. The compound of claim 1 , wherein n is 4.6. The compound of claim 1 , wherein n is 5.7. The compound of claim 1 , wherein X is (CH)and z is 0.8. The compound of claim 1 , wherein each occurrence of Rand Rand the carbon to which they are both attached are taken together to form a (C-C)cycloakyl group.9. The compound of claim 1 , wherein Yand Yare each independently (C-C)alkyl.10. The compound of claim 1 , wherein Yand Yare each methyl.1157-. (canceled) This application claims the benefit of U.S. Provisional Application No. 60/441,795, filed Jan. 23, 2003, which is incorporated herein by reference in its entirety.The invention relates to cycloalkyl-hydroxyl compounds and pharmaceutically acceptable salts, hydrates, solvates, and mixtures thereof ...

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Номер записи: 49
16-03-2017 дата публикации

SALT AND CRYSTALLINE FORMS THEREOF OF A DRUG

Номер: US20170073329A1
Автор: BARNES David M., Bradley Michael F., Henry Rodger, Zhang Geoff G.Z.
Принадлежит:

A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed. 1. A process for making D-glucitol , 1-deoxy-1-(methylamino)- , 1-(6-amino-3 ,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1 ,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylate salt comprising the steps of:(1) combining 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy azetidin-1-yl)-4-oxo-3-quinolinecarboxylate and 1-deoxy-1-(methylamino)-D-glucitol in a solvent to provide a mixture;(2) filtering said mixture to provide a solid; and(3) drying said solid to provide said D-glucitol, 1-deoxy-1-(methylamino)-, 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy azetidin-1-yl)-4-oxo-3-quinolinecarboxylate salt.2. The process of claim 1 , wherein said solvent comprises water.3. The process of claim 1 , wherein said solvent comprises an alcohol.4. The process of claim 3 , wherein said alcohol is isopropanol.5. The process of claim 4 , wherein said step of combining said 1-(6-amino-3 claim 4 ,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1 claim 4 ,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylate and said 1-deoxy-1-(methylamino)-D-glucitol in a solvent to provide a mixture further comprises heating said mixture.6. The process of claim 5 , wherein said heating comprises about 60° C.7. The process of claim 5 , wherein said heating comprises about 45° C.8. The process of claim 1 , wherein said step of combining said 1-(6-amino-3 claim 1 ,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1 claim 1 ,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylate and said 1-deoxy-1-(methylamino)-D-glucitol in a solvent to provide a mixture further comprises heating said mixture and subsequently cooling said mixture.9. The process of claim 8 , wherein said heating comprises about 60° C.10. The process of claim 8 , wherein ...

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Номер записи: 50
05-03-2020 дата публикации

UTILIZATION OF NORMAL CARBON 4 (NC4) RECYCLE STREAM FOR SECONDARY AND TERTIARY PRODUCTS

Номер: US20200071286A1
Автор: AL OTAIBE Sultan, ANSARI Mohammed Bismillah, BODAS Vijay, LEAL Guillermo
Принадлежит:

Certain embodiments are directed to an integrated process for the production of Maleic Anhydride (MAN), 1,4 Butanediol (BDO), Gamma-ButyroLactone (GBL), and PolyButylene Terephthalate (PBT) utilizing NC4 rich stream from a recycle stream after or before processing by a Total Hydrogenation Unit (THU). 1. A method of forming products from C4 hydrocarbons in an olefin producing plant; the method comprising:receiving, from a hydrogenation unit, a hydrocarbon stream comprising primarily C4 hydrocarbons;contacting, in a reactor unit, the hydrocarbon stream with a catalyst under reaction conditions to form maleic anhydride; andconverting, in one or more finished product units, at least some of the maleic anhydride to one or more of: 1,4 butanediol (BDO), gamma-butyrolactone (GBL), or tetrahydrofuran (THF), wherein the hydrogenation unit is in fluid communication with the reactor unit and the reactor unit is in fluid communication with the one or more finished product units.2. The method of claim 1 , wherein the feed stream for the hydrogenation unit is a side product stream received from a butane separation unit.3. The method of claim 2 , wherein the feed stream for the butane separation unit is a side stream received from a methyl tertiary butyl ether (MTBE) production unit.4. The method of claim 3 , wherein a feed stream for the MTBE production unit is received from a selective hydrogenation unit (SHU).5. The method of claim 4 , wherein a feed stream for the SHU is received from a butadiene production unit.6. The method of claim 5 , wherein a feed stream for the butadiene production unit is received from a debutanizer unit coupled to steam cracking unit.7. The method of claim 5 , wherein a feed stream for the butadiene production unit is received from a steam cracking unit.8. A method of forming products from C4 hydrocarbons in an olefin producing plant that utilizes a steam cracker unit; the method comprising:receiving, from a hydrogenation unit, a hydrocarbon stream ...

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Номер записи: 51
05-06-2014 дата публикации

Salt and Crystalline Forms Thereof of a Drug

Номер: US20140155380A1
Автор: BARNES David M., Bradley Michael F., Henry Rodger, Zhang Geoff G.Z.
Принадлежит: AbbVie Inc.

A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed. 1. A therapeutic composition comprising D-Glucitol , 1-deoxy-1-(methylamino)- , 1-(6-amino-3 ,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1 ,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylate salt , at least one filler , at least one binder , at least one disintegrating agent , at least one buffering agent and at least one lubricant.2. The composition of claim 1 , wherein the salt is present in a therapeutically acceptable amount.3. The composition of claim 1 , wherein the salt is crystalline.4. The composition of claim 3 , wherein the salt has substantial crystalline purity.5. The composition of claim 4 , wherein the salt has at least about 95% crystalline purity.6. The composition of claim 3 , wherein the salt is characterized claim 3 , when measured at about 25° C. with Cu—Kα radiation claim 3 , by the powder diffraction pattern shown in .7. The composition of claim 3 , wherein the salt is characterized by respective lattice parameters claim 3 , a claim 3 , b claim 3 , and c of about 16.4460 Å claim 3 , 21.4010 Å claim 3 , and 5.3050 Å and β of about 109° in the monoclinic crystal system P 21/C or P 21/M space group claim 3 , when measured with Mo—Kα radiation at about 25° C.8. The composition of claim 1 , wherein the salt has substantial chemical purity.9. The composition of claim 8 , wherein the salt is about 97% chemically pure.10. The composition of claim 8 , wherein the salt is about 98% chemically pure.11. The composition of claim 8 , wherein the salt is about 100% chemically pure.12. The composition of claim 1 , wherein the composition is an orally administered dosage form.13. The composition of claim 1 , wherein the at least one filler comprises cellulose.14. The composition of claim 1 , wherein the at least one binder comprises povidone.15. The composition of ...

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Номер записи: 52
12-03-2020 дата публикации

MEG RECOVERY APPARATUS AND MEG RECOVERY METHOD

Номер: US20200078702A1
Автор: KIM Hyunho, SEO Yutaek
Принадлежит:

Provided are a mono-ethylene glycol (MEG) recovery apparatus and a MEG recovery method. The MEG recovery apparatus includes a pretreater receiving the raw material from a raw material supplier to remove the low soluble salts, a first distiller connected to the pretreater to receive the raw material from which the low soluble salts are removed, and to form a first treated solution by vaporizing a certain amount of the water, a high soluble salt remover connected to the first distiller to remove the high soluble salts from the first treated solution, a second distiller connected to the high soluble salt remover to form a second treated solution by vaporizing the water from the first treated solution from which the high soluble salts are removed, and a recovery unit connected to the second distiller to recover the second treated solution. 1. An apparatus for recovering mono-ethylene glycol (MEG) from a raw material including water , the MEG , high soluble salts , and low soluble salts , the apparatus comprising:a pretreater receiving the raw material from a raw material supplier to remove the low soluble salts;a first distiller connected to the pretreater to receive the raw material from which the low soluble salts are removed, and to form a first treated solution by vaporizing a certain amount of the water;a high soluble salt remover connected to the first distiller to remove the high soluble salts from the first treated solution;a second distiller connected to the high soluble salt remover to form a second treated solution by vaporizing the water from the first treated solution from which the high soluble salts are removed; anda recovery unit connected to the second distiller to recover the second treated solution.2. The apparatus of claim 1 , wherein the first distiller vaporizes the water in such a manner that the first treated solution has a MEG value of 60 wt % to 75 wt %.3. The apparatus of claim 2 , wherein deposition of the high soluble salts in the first ...

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Номер записи: 53
25-03-2021 дата публикации

1,2-ALKANEDIOLS AND A PROCESS FOR THEIR PRODUCTION

Номер: US20210085579A1
Автор: Lange Sabine, Schmaus Gerhard, SIEWERT Jürgen, STEPHAN Torsten, WINKLER Sven
Принадлежит:

Suggested are 1,2-alkanediols of formula (I) HOCH—CH(OH)—Rin which Rstands for an alkyl radical having 3 to 10 carbon atoms, said diols being substantially free of lactones and/or peroxides. 1. A 1 ,2-alkanediol of formula (I){'br': None, 'sub': '2', 'sup': '1', 'HOCH—CH(OH)—R'}{'sup': '1', 'in which Rstands for an alkyl radical having 3 to 10 carbon atoms, said diol being substantially free of lactones and/or peroxides.'}2. The diol of claim 1 , wherein said diol is substantially free of lactones selected from the group consisting of γ-pentalactone claim 1 , γ-hexalactone claim 1 , γ-heptalactone claim 1 , γ-octalactone claim 1 , γ-nonalactone claim 1 , γ-decalactone claim 1 , γ-undecalactone claim 1 , γ-dodecalactone claim 1 , γ-tetralactone claim 1 , and mixtures thereof.3. The diol of claim 1 , wherein the content of lactones and/or said peroxides in said diol is less than 1 GC area-% or 1% b.w. respectively.4. The diol of selected from the group consisting of 1 claim 1 ,2-pentanediol claim 1 , 1 claim 1 ,2-hexanediol claim 1 , 1 claim 1 ,2-octanediol claim 1 , 1 claim 1 ,2-decanediol claim 1 , 1 claim 1 ,2-dodecanediol claim 1 , and mixtures thereof.5. A 1 claim 1 ,2-alkanediol of formula (I){'br': None, 'sub': '2', 'sup': '1', 'HOCH—CH(OH)—R'}{'sup': '1', 'in which Rstands for an alkyl radical having 3 to 10 carbon atoms, said diol being substantially free of lactones, and obtained by the following steps(a) providing at least one 1,2-olefin having 5 to 12 carbon atoms;(b) adding formic acid and hydrogen peroxide to form a first mixture;(c) heating the first mixture of step (b) to produce a second mixture comprising the corresponding 1,2-alkanediol mono and diformates;(d) subjecting the second mixture of step (c) to a catalytic working amount of a decarbonylation catalyst to form a third mixture;(e) heating the third mixture of step (d) to a temperature of from about 150 to about 250° C. to decompose said formates and form the respective diols and carbon ...

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Номер записи: 54
12-03-2020 дата публикации

NUCLEATING AGENTS, METHODS FOR THEIR PRODUCTION, AND ASSOCIATED POLYMER COMPOSITIONS

Номер: US20200079929A1
Автор: Dabbous Raphaël, HORTON Murray, JAYARATNE Vidura Nalin, TURNEY Terence William
Принадлежит:

A method of manufacture of zinc monoglycerolate containing an incorporated modifier, and the product, the zinc monoglycerolate being in the form of agglomerates of crystallites, wherein the crystallite size based on the average coherence domain length is not more than 30 nm in the <100> direction, and not more than 60 nm in the <011> direction, as determined by the Scherrer equation via powder X-ray diffraction; and the aspect ratio computed by <100>/<011> coherent domain lengths is less than 0.65, preferably less than 0.56, in particular less than 0.44. Polymers containing this nucleating agent and methods for their production are also described. The zinc monoglycerolate is useful as a nucleating agent, and is very effective at low loading levels in polymers such as polypropylene. 1: A zinc monoglycerolate in the form of agglomerates of crystallites , wherein:a crystallite size of the zinc monoglycerolate, based on average coherence domain length, is less than 30 nm in the <100> direction (size along the <100> zone axis), and less than 60 nm in the <011> direction (size along the <100> zone axis), as determined by the Scherrer equation via powder X-ray diffraction; andan aspect ratio of the zinc monoglycerolate, computed by <100>/<011> coherent domain lengths, is less than 0.65.2: The zinc monoglycerolate according to claim 1 , comprising a modifier.3: The zinc monoglycerolate according to claim 2 , wherein the modifier is a glycerol carboxylate ester.4: The zinc monoglycerolate according to claim 3 , wherein the glycerol carboxylate ester is a saturated fatty acid ester of glycerol.5: The zinc monoglycerolate according to claim 4 , wherein the glycerol carboxylate ester is glycerol monostearate.6: The zinc monoglycerolate according to claim 2 , wherein an amount of modifier is between 1.0 and 5.0 mol % with respect to the zinc monoglycerolate.7: A zinc monoglycerolate in the form of agglomerates of crystallites claim 2 , comprising between 1.0 and 5.0 mol % of a ...

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Номер записи: 55
25-03-2021 дата публикации

CONTINUOUS, CARBOHYDRATE TO ETHYLENE GLYCOL PROCESSES

Номер: US20210087125A1
Автор: Albin Brooke, Bradford Michael, Bunning Donald, Chrisman Ray, Kapicak Lou, Nunley Mark, Schreck David James
Принадлежит:

By this invention processes are provided for the conversion of carbohydrate to ethylene glycol by retro-aldol catalysis and sequential hydrogenation using control methods having at least one of acetol (hydroxyacetone) and a tracer as inputs. 1. A continuous process having a control system to control one or more operating parameters based on one or more inputs for the catalytic conversion of a carbohydrate feed containing at least aldose-yielding or ketose-yielding carbohydrate to lower glycol of at least one of ethylene glycol and propylene glycol in an unmodulated reaction zone by sequential retro-aldol catalytic conversion under retro-aldol conditions , including the presence of a retro-aldol catalyst providing retro-aldol catalytic activity in a liquid medium in the unmodulated reaction zone , to intermediates and catalytic hydrogenation of intermediates under hydrogenation conditions , including the presence of hydrogen and hydrogenation catalyst providing hydrogenation catalytic activity , to lower glycol , in the unmodulated reaction zone , and withdrawing continuously or intermittently from said unmodulated reaction zone , a raw product , said process comprising controlling at least one operating parameter of the process using at least the concentration of acetol in the raw product is an input to the control system for the process.2. The process of wherein the carbohydrate comprises aldose and the lower glycol comprises ethylene glycol.3. The process of wherein in response to an increase in acetol concentration claim 2 , at least one of (i) the hydrogenation catalytic activity is increased and (ii) at least one of the rate of supply of the carbohydrate feed and the concentration of carbohydrate in the feed is decreased.4. The process of wherein the retro-aldol catalyst is homogeneous and the hydrogenation catalyst is heterogeneous.5. The process of wherein the concentration of acetol is compared with concentrations of at least one of itol claim 2 , 1 claim 2 ...

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Номер записи: 56
25-03-2021 дата публикации

METHOD FOR PURIFYING BY-PRODUCT ETHYLENE GLYCOL OF POLYESTER IN CONVERTING PLASTICIZER

Номер: US20210087130A1
Автор: Chen Chung-Yu, CHUANG Jung-Jen, LAI Chiou-Nan, LIAO Te-Chao
Принадлежит:

A method for purifying by-product ethylene glycol of polyester in converting plasticizer includes: inputting a reaction liquid waste stream including ethylene glycol and 2-ethylhexanol into an ethylene glycol dehydration tower; inputting a hot water stream into the ethylene glycol dehydration tower to mix with the reaction liquid waste stream and to remove the 2-ethylhexanol from the reaction liquid waste stream; dehydrating the ethylene glycol via the ethylene glycol dehydration tower to collect a crude ethylene glycol stream including dehydrated ethylene glycol from a tower bottom of the ethylene glycol dehydration tower and to collect an organic liquid waste stream including the 2-ethylhexanol from a tower top of the ethylene glycol dehydration tower; and inputting the crude ethylene glycol stream into an ethylene glycol distillation tower to collect a ethylene glycol solution from a tower top of the ethylene glycol distillation tower. 1. A method for purifying by-product ethylene glycol of polyester in converting plasticizer , which is a continuous collection method and comprises the following steps (1) to (4):(1) inputting a reaction liquid waste stream into an ethylene glycol dehydration tower; wherein the reaction liquid waste stream includes ethylene glycol and 2-ethylhexanol;(2) inputting a hot water stream into the ethylene glycol dehydration tower to mix with the reaction liquid waste stream and to remove the 2-ethylhexanol from the reaction liquid waste stream so that the ethylene glycol is separated from the 2-ethylhexanol; wherein the hot water stream is heated water, and a temperature of the hot water stream is between 40° C. and 95° C.;(3) dehydrating the ethylene glycol via the ethylene glycol dehydration tower to collect a crude ethylene glycol stream from a tower bottom of the ethylene glycol dehydration tower and to collect an organic liquid waste stream from a tower top of the ethylene glycol dehydration tower; wherein the crude ethylene glycol ...

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Номер записи: 57
29-03-2018 дата публикации

CONTINUOUS PROCESSES FOR THE HIGHLY SELECTIVE CONVERSION OF SUGARS TO PROPYLENE GLYCOL OR MIXTURES OF PROPYLENE GLYCOL AND ETHYLENE GLYCOL

Номер: US20180086681A1
Автор: Albin Brooke, Bradford Marion McKinley, Bunning Donald, Chrisman Ray, Clinton Nye, Schreck David James
Принадлежит:

Continuous processes for making propylene glycol from ketose-yielding carbohydrates are disclosed which enhance the selectivity to propylene glycol. 2. The process of wherein the feed comprises ketose-yielding and aldose-yielding carbohydrate and a mixture of propylene glycol and ethylene glycol is contained in the product solution.3. The process of wherein the feed comprises sucrose.4. The process of wherein the product solution contains a mass ratio of 1 claim 1 ,2-butanediol to total propylene glycol and ethylene glycol of less than about 1:10.5. The process of wherein the aqueous solution is maintained at a temperature of greater than about 170° C. and less than 230° C. for less than about 15 seconds prior to being passed into the aqueous-hydrogenation medium.6. The process of wherein the heating of the carbohydrate feed from below 170° C. to above 230° C. is at least in part by direct heat exchange by admixing the carbohydrate feed with a warmer fluid.7. The process of wherein the warmer fluid comprises the aqueous-hydrogenation medium.8. The process of wherein the admixing of the carbohydrate feed and warmer fluid involves high shear mixing.9. The process of wherein the admixing of the carbohydrate feed and warmer fluid involves rapid diffusional mixing.10. The process of wherein the heating of the carbohydrate feed from below 170° C. to above 230° C. is at least in part by indirect heat exchange.14. The process of wherein the heating of the carbohydrate feed from below 170° C. to above 230° C. occurs whereupon the carbohydrate is contacted with an aqueous claim 1 , retro-aldol solution containing retro-aldol catalyst in the substantial absence of hydrogenation catalyst.15. The process of wherein the carbohydrate-containing feed contains between about 120 and 800 grams of carbohydrate per liter of aqueous-hydrogenation medium.16. The process of wherein the carbohydrate-containing feed contains aldose and the rate of heating of the carbohydrate feed from below ...

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Номер записи: 58
21-03-2019 дата публикации

INTEGRATED PROCESS FOR POLY OLEFIN PRODUCTION WITH REDUCED GREENHOUSE GAS EMISSION

Номер: US20190084902A1
Автор: Fowler Nick, Lawrence Deborah, McHANEY Steve
Принадлежит:

A substantially zero carbon emission process for making amorphous poly alpha olefins including, converting alkanes to olefin monomers ethylene, propylene, and 1-butene or combinations thereof using renewable electric power in an oxidative-coupling of methane plant including the steps of passing alkanes through an ethylene plant while adding oxygen, passing the first polymerization grade ethylene through a 2-butene plant, passing a first of the two 2-butene streams and one of the polymerization grade ethylene through a propylene plant, and passing a second of the two 2-butene streams through a 1-butene plant. The next step in the process for making amorphous poly alpha olefins includes polymerizing at least one of the polymerization grade alkenes which includes applying a temperature of 130 degrees Fahrenheit to 175 degrees Fahrenheit to at least one of the polymerization grade alkenes and scrubbing at least one boiler stack gases. 1. A substantially zero emission process for making amorphous poly alpha olefins comprising: (i) using an ethylene plant to make ethylene from a natural gas with oxygen;', '(ii) using a 2-butene plant to convert the ethylene to create two 2-butene streams;', '(iii) using a propylene plant to convert the first 2-butene stream and some of the ethylene to form propylene;', {'b': '10', '(iv) using a 1-butene plant isomerize the second 2-butene stream into 1-butene;'}], 'a. converting alkanes to the olefin monomers ethylene, propylene, and butene or combinations thereof using renewable electric power in an oxidative-coupling of methane (OCM) plant, the steps comprising (i) applying a temperature of 130 degrees to 175 degrees Fahrenheit to the 1-butene, propylene or ethylene from the olefins plant;', '(ii) using renewable electric power while scrubbing at least one boiler stack gasses, with a solvent to sequester carbon dioxide from the boiler stack gas forming amorphous poly alpha olefin., 'b. polymerizing any one of the created 1-butene, ...

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Номер записи: 59
21-03-2019 дата публикации

CYCLOALKYL-HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES

Номер: US20190084908A1
Автор: Dasseux Jean-Louis H., Oniciu Carmen D.
Принадлежит:

The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents. 157-. (canceled)59. The method claim 58 , wherein each occurrence of Yand Yis independently COORor COOH.60. The method of claim 59 , wherein m is 0.61. The method of claim 59 , wherein m is 1.62. The method of claim 59 , wherein n is 4.63. The method of claim 59 , wherein n is 5.64. The method of claim 59 , wherein X is (CH2)and z is 0.67. The method of claim 58 , the method further comprising administering to a patient in need of such treatment a therapeutically effective amount of a second therapeutic agent.68. The method of claim 67 , wherein the second therapeutic agent is selected from the group consisting of a chemotherapeutic agent claim 67 , an alkylating agent claim 67 , a plant alkaloid claim 67 , a DNA topoisomerase inhibitor claim 67 , a mitomycin claim 67 , an anti-folate claim 67 , a pyrimidine analog claim 67 , a purine analog claim 67 , a hormonal therapy claim 67 , a retinoid claim 67 , a deltoid claim 67 , a vitamin D3 analog ...

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Номер записи: 60
21-03-2019 дата публикации

Terephthalic acid esters formation

Номер: US20190084916A1
Автор: Adel ESSADDAM, Fares ESSADDAM
Принадлежит: 9449710 Canada Inc

The present disclosure relates to the formation of terephthalate esters. The present invention also relates to the depolymerization of polyethylene terephthalate (PET) or poly(ethylene glycol-co-1,4-cyclohexanedimethanol terephthalate) and the recovery of terephthalate esters.

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Номер записи: 61
31-03-2016 дата публикации

Removing impurities from sugar solutions

Номер: US20160090641A1
Автор: Fengshan Luo, Gongwei PU, Yi Shu
Принадлежит: Dow Chemical China Investment Co Ltd

Provided is a process for removing impurities from a solution (S1), wherein said solution (S1) comprises one or more sugar dissolved in an aqueous solvent, wherein said solution (S1) has conductivity at 25° C. of 500 μS/cm or higher, and wherein said process comprises (a) contacting said solution (S1) with a cation exchange resin (R1) to produce a solution (S2) in which 80% or more of the cations are all of the same element (E); and (b) then contacting said solution (S2) with a cation exchange resin (R2) in which, prior to said contacting, 90% or more of acid groups are in the salt form with said element (E). Also provided is a process for producing glycols comprising providing an extract solution by the process of claim 1, and then contacting said solution (S3) with hydrogen and a metal catalyst.

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Номер записи: 62
05-05-2022 дата публикации

CONTINUOUS PROCESSES FOR THE SELECTIVE CONVERSION OF ALDOHEXOSE-YIELDING CARBOHYDRATE TO ETHYLENE GLYCOL USING LOW CONCENTRATIONS OF RETRO-ALDOL CATALYST

Номер: US20220135505A1
Автор: Albin Brooke, Bradford Michael, Bunning Donald, Kapicak Louis A., Nunley Mark, Schreck David James
Принадлежит:

Retro-aldol processes are disclosed that use very low concentrations of retro-aldol catalyst in combination with hydrogenation catalyst of certain activities, sizes and spatial dispersions to obtain the high selectivities to ethylene glycol.

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Номер записи: 63
19-03-2020 дата публикации

Methods and Compositions for Hydrodeoxygenation of Carbohydrates and Carbohydrate Analogs

Номер: US20200087234A1
Автор: BARROW ELIZABETH, Lauterbach Jochen, MACQUEEN BLAKE
Принадлежит:

This disclosure provides embodiments directed to compositions, methods, and processes to produce compounds having the structure: 3. The method of claim 1 , wherein the carbohydrate or carbohydrate derivative is selected from the group consisting of: an aldose claim 1 , a ketose claim 1 , a sugar alcohol claim 1 , and a sugar acid.5. The method of claim 4 , wherein each of R10-R14 is selected from the group consisting of: a hydroxyl group claim 4 , and a hydrogen.6. The method of claim 4 , wherein each of R10-R14 is a hydroxyl group.7. The method of claim 1 , wherein reacting the precursor with a gas occurs at a reaction temperature between about 100° C. to about 240° C.8. The method of claim 7 , wherein the reaction temperature is between about 120° C. to about 200° C.9. The method of claim 7 , wherein the reaction temperature is between about 130° C. to about 180° C.10. The method of claim 7 , wherein the reaction pressure is between about 4 bar and about 25 bar.11. The method of claim 1 , wherein reacting the precursor with a gas occurs at a catalyst loading between about 1 wt % to about 25 wt %.12. The method of claim 11 , wherein the catalyst loading is between about 2 wt % and about 6 wt %.13. The method of claim 1 , wherein the catalyst comprises a support impregnated with at least one transition metal selected from the group consisting of: Re claim 1 , Os claim 1 , Ir claim 1 , Pt claim 1 , Au claim 1 , Rh claim 1 , Pd claim 1 , and Cu.14. The method of claim 13 , wherein the support comprises CeOand wherein claim 13 , the support is impregnated with both Re and Pd.15. The method of claim 14 , wherein the catalyst is impregnated with less than 10 wt % Re and less than 10 wt % Pd.16. The method of claim 14 , wherein the catalyst is impregnated with less than 5 wt % Re and less than 3 wt % Pd.17. The method of claim 1 , wherein the gas containing His greater than 90 vol % H.18. A process for converting a carbohydrate or carbohydrate derivative to a compound ...

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Номер записи: 64
30-03-2017 дата публикации

Polymer compound and light emitting device using the same

Номер: US20170092864A1
Автор: Mio SHIRATORI, Tomoyasu Yoshida
Принадлежит: Sumitomo Chemical Co Ltd

A polymer compound comprising a constitutional unit having a group represented by the formula (1): wherein Ring A 1A and Ring R 2A represent an aromatic hydrocarbon ring or a heterocyclic ring and these rings each optionally have a substituent, nA represents an integer of 0 to 5, nB represents an integer of 1 to 5, L A and L B represent an alkylene group, a cycloalkylene group, an arylene group, a divalent heterocyclic ring group, a group represented by —NR′—, an oxygen atom or a sulfur atom, and R′ represents a hydrogen atom, an alkyl group or the like, and Q 1 represents a crosslinkable group.

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Номер записи: 65
06-04-2017 дата публикации

PRODUCTION OF PARTIALLY REFINED WASTE GLYCEROL

Номер: US20170096379A1
Автор: KO Myong, Li Simon, LIAO Perry, Sanchez-Riera Fernando
Принадлежит:

The disclosure relates to a novel glycerol purification process that produces partially refined waste glycerol for a variety of industrial applications. The disclosure encompasses a salt-containing partially refined glycerol composition that is suitable as a fermentation grade glycerol. 128.-. (canceled)29. A partially refined waste glycerol produced by a process comprising: subjecting crude glycerol to a hydrophobic solvent to produce a mixture of crude glycerol and hydrophobic solvent , and separating the mixture of crude glycerol and hydrophobic solvent to produce a deoiled (DO) glycerol and a phase containing hydrophobic solvent and organic impurities.3031.-. (canceled)32. The partially refined waste glycerol of claim 29 , wherein said partially refined waste glycerol comprises reduced salt and organic impurities as compared to a crude glycerol.33. The partially refined waste glycerol of claim 32 , wherein said partially refined waste glycerol comprises a sodium chloride content from between about 0.05 percent to about 8.2 percent.34. The partially refined waste glycerol of claim 32 , wherein said partially refined waste glycerol comprises a sodium chloride content from between about 0.05 percent to about 3.5 percent.35. The partially refined waste glycerol of claim 32 , wherein said partially refined waste glycerol comprises a sodium chloride content from between about 0.05 percent to about 2.0 percent.36. The partially refined waste glycerol of claim 32 , wherein said partially refined waste glycerol comprises a sodium chloride content from between about 0.05 percent to about 1.0 percent.37. The partially refined waste glycerol of claim 32 , wherein said partially refined waste glycerol is a fermentation grade glycerol.3855.-. (canceled) The disclosure relates to a novel glycerol purification process that produces partially refined waste glycerol for a variety of industrial applications. Herein, the disclosure encompasses a salt-containing partially refined ...

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Номер записи: 66
26-03-2020 дата публикации

DIRECT OXIDATION OF OLEFINS TO OXYGENATED SPECIES

Номер: US20200095183A1
Автор: HASHIGUCHI Brian G., KONNICK Michael M., PERIANA Roy A.
Принадлежит:

Provided is a process for oxidizing an alkene. The process comprises contacting an alkene, and either an oxidizing electrophile comprising a main group element in oxidized form or an oxidant and a reduced form of the oxidizing electrophile, in a liquid medium comprising an oxygen acid and optionally one or more additives selected from a non-oxidizable liquid, a salt additive, a Lewis acid, and water, to provide an oxygenate and a reduced form of the oxidizing electrophile. The process optionally further comprises separating the oxygenate and the reduced form of the oxidizing electrophile. The oxygenate can be further hydrolyzed to form an alcohol, diol, or polyol. 1. A process for oxidizing an alkene , comprising:(a) contacting an alkene, and(i) an oxidizing electrophile comprising a main group element in oxidized form, or(ii) an oxidant and a reduced form of the oxidizing electrophile,in a liquid medium comprising an oxygen acid and optionally one or more additives selected from a non-oxidizable liquid, a salt additive, a Lewis acid, and water, to provide an oxygenate and a reduced form of the oxidizing electrophile; and(b) optionally separating the oxygenate and the reduced form of the oxidizing electrophile.2. The process of claim 1 , comprising (b) separating the oxygenate and the reduced form of the oxidizing electrophile.3. (canceled)4. The process of claim 1 , further comprising (c) hydrolyzing the oxygenate to form an alcohol claim 1 , a diol claim 1 , a polyol with three or more hydroxyl groups claim 1 , or a combination thereof.5. (canceled)6. The process of claim 4 , wherein the hydrolysis step takes place in the presence of an acid.7. The process of claim 4 , wherein the hydrolysis step takes place in the presence of a base.8. (canceled)9. (canceled)10. The process of claim 1 , wherein the oxidizing electrophile comprises thallium claim 1 , lead claim 1 , antimony claim 1 , mercury claim 1 , tin claim 1 , selenium claim 1 , tellurium claim 1 , arsenic ...

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Номер записи: 67
08-04-2021 дата публикации

METHODS OF SUSTAINING DIETARY KETOSIS AND ITS EFFECTS ON LIPID PROFILE

Номер: US20210100766A1
Автор: "DAgostino Dominic Paul", Kesl Shannon
Принадлежит:

The ketogenic diet (KD) has therapeutic implications in many disease states. It was hypothesized ketone precursor supplementation would elevate blood ketone levels to therapeutic ranges (2-7 mM) without need for dietary restriction. The effects of ketogenic agents were tested on blood glucose, ketones, and lipids with a 28-day dose escalation study in male Sprague-Dawley rats: R,S-1,3-Butandiol (BD), acetoacetate ketone ester (KE), and control (HO) (n≥8). Days 1-28, rats received a daily 5g/kg intragastric gavage, based on previous toxicology studies. Once weekly, whole blood samples (10 μl) were acquired for analysis of glucose and βHB at 0, 0.5, 1, 4, 8, and 12 hours after test substance administration, or until βHB returned to baseline. At day 1 and 28, 10 μL of whole blood were collected to measure triglycerides, total cholesterol, and HDL concentration. Significant elevation of blood ketone was observed with a significant inverse relationship with blood glucose for the duration of the experiment. There were no significant changes in the lipid panel for any of the substances. There were significant reductions in body weight when animals were treated with either BD or KE as compared to control. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. A method of reducing fatigue during exercise comprising:administering a therapeutically effective amount of a composition comprising a ketogenic agent to elevate one or more ketone bodies for at least four (4) hours and reduce fatigue during exercise in the human subject;wherein the ketogenic agent is 1,3-butanediol acetoacetate monoester; 1,3-butanediol acetoacetate diester; R,S-1,3-butanediol diacetoacetate ester; R-1,3-butanediol diacetoacetate ester, a combination of 1,3-butandiol and 1,3-butanediol acetoacetate diester, or a combination thereof,wherein administration of the composition achieves ketosis in the human subject, and wherein the human subject consumes an average of ...

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Номер записи: 68
12-04-2018 дата публикации

MODIFIED MICROORGANISM FOR THE OPTIMIZED PRODUCTION OF 2,4-DIHYDROXYBUTYRATE

Номер: US20180100169A1
Автор: BESTEL-CORRE Gwénaëlle, Dumon-Seignovert Laurence, Soucaille Philippe
Принадлежит: METABOLIC EXPLORER

The present invention relates to a genetically modified microorganism for the production of 2,4-dihydroxybutyrate, by metabolic transformation of xylose via the 1,2,4-butanetriol intermediate. The invention also relates to a method for the production of 2,4-dihydroxybutyrate by culturing said genetically modified microorganism in a fermentation medium and recovering 2,4-DHB from said medium. 1. A microorganism genetically modified for the production of 2 ,4-dihydroxybutyrate by converting xylose into 1 ,2 ,4-butanetriol , wherein said microorganism is further genetically modified for:i) oxidizing 1,2,4-butanetriol into 2,4-dihydroxybutanal; andii) oxidizing 2,4-dihydroxybutanal into 2,4-dihydroxybutyrate.2. The microorganism according to claim 1 , wherein the genetic modification i) is an overexpression of at least one gene encoding an oxidoreductase acting on the CH—OH group of donors.3. The microorganism according to claim 2 , wherein said oxidoreductase is selected from the group consisting of alcohol dehydrogenases claim 2 , lactaldehyde reductases claim 2 , glyoxylate reductases claim 2 , didehydrogluconate reductases claim 2 , and any combination thereof.4. The microorganism according to claim 1 , wherein the genetic modification ii) is an overexpression of at least one gene encoding an oxidoreductase acting on the aldehyde or oxo group of donors.5. The microorganism according to claim 4 , wherein said oxidoreductase is selected from the group consisting of an aldehyde dehydrogenase claim 4 , an aldehyde oxidase claim 4 , and any combination thereof.6. The microorganism according to claim 1 , wherein the genetic modification for converting xylose into 1 claim 1 ,2 claim 1 ,4-butanetriol is an overexpression of at least one of the following genes:a gene encoding a xylose dehydrogenase,a gene encoding a xylonolactonase,a gene encoding a xylonate dehydratase,a gene encoding a 3-deoxy-D-glycero-pentulosonate decarboxylase,a gene encoding a 1,2,4-butanetriol ...

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Номер записи: 69
08-04-2021 дата публикации

PROCESS AND SYSTEMS FOR OBTAINING 1,3-BUTANEDIOL FROM FERMENTATION BROTHS

Номер: US20210101855A1
Автор: Khandurina Julia, Pacheco Rachel Diane, Suominen Lauri Hannunpoika, Wagester Rainer
Принадлежит:

Provided herein are bioderived 1,3-butanediol compositions and systems and processes for producing such bioderived 1,3-butanediol compositions. 1. Bioderived 1 ,3-butylene glycol (1 ,3-BG) , wherein the bioderived 1 ,3-BG comprises detectable levels of one or more compounds selected from the group consisting of 3-hydroxy-butanal , 4-hydroxy-2-butanone , 4-(3-hydroxybutoxy)butan-2-one , 4-((4-hydroxybutan-2-yl)oxy)-butan-2-one , 1 ,2-propanediol , 1 ,3-propanediol and 2 ,3-butanediol.2. The bioderived 1 claim 1 ,3-BG of claim 1 , wherein the bioderived 1 claim 1 ,3-BG comprises detectable levels of 3-hydroxy-butanal claim 1 , 4-hydroxy-2-butanone claim 1 , 4-(3-hydroxybutoxy)butan-2-one and 4-((4-hydroxybutan-2-yl)oxy)-butan-2-one.3. The bioderived 1 claim 1 ,3-BG of or claim 1 , wherein the bioderived 1 claim 1 ,3-BG comprises higher levels of one or more compound selected from the group of 3-hydroxy-butanal claim 1 , 4-hydroxy-2-butanone claim 1 , 4-(3-hydroxybutoxy)butan-2-one and 4-((4-hydroxybutan-2-yl)oxy)-butan-2-one than petro-BG.4. The bioderived 1 claim 1 ,3-BG of any one of - claim 1 , wherein the chiral purity of the bioderived 1 claim 1 ,3-BG is 95% or more claim 1 , 96% or more claim 1 , 97% or more claim 1 , 98% or more claim 1 , 99.0% or more claim 1 , 99.1% or more claim 1 , 99.2% or more claim 1 , 99.3% or more claim 1 , 99.4% or more claim 1 , 99.5% or more claim 1 , 99.6% or more claim 1 , 99.7% or more claim 1 , 99.8% or more claim 1 , or 99.9% or more.5. The bioderived 1 claim 4 ,3-BG of claim 4 , wherein the bioderived 1 claim 4 ,3-BG has a chemical purity of 99.0% or more claim 4 , 99.1% or more claim 4 , 99.2% or more claim 4 , 99.3% or more claim 4 , 99.4% or more claim 4 , 99.5% or more claim 4 , 99.6% or more claim 4 , 99.7% or more claim 4 , 99.8% or more claim 4 , or 99.9% or more.6. The bioderived 1 claim 4 ,3-BG of any one of - claim 4 , wherein the bioderived 1 claim 4 ,3-BG comprises more R-enantiomer than S-enantiomer.7. The ...

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Номер записи: 70
19-04-2018 дата публикации

SALT AND CRYSTALLINE FORMS THEREOF OF A DRUG

Номер: US20180105510A1
Автор: BARNES David M., Bradley Michael F., Henry Rodger, Zhang Geoff G.Z.
Принадлежит:

A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed. 1. A therapeutic composition comprising crystalline D-glucitol , 1-deoxy-1-(methylamino)- , 1-(6-amino-3 ,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-1 ,4-dihydro-7-(3-hydroxyazetidin-1-yl)-4-oxo-3-quinolinecarboxylate salt and an excipient , wherein the therapeutic composition is in a dosage form selected from the group consisting of a capsule , a dragee , an emulsion , a granule , a pill , a powder , a solution , a suspension , a tablet , a microemulsion , an elixir , a syrup , a powder for reconstitution , a cream , a gel , an inhalant , a lotion , an ointment , a paste , a powder , an aqueous suspension , and an oleaginous suspension.2. The therapeutic composition of claim 1 , wherein the salt is present in a therapeutically effective amount.3. The therapeutic composition of claim 1 , wherein the salt has substantially crystalline purity.4. The therapeutic composition of claim 3 , wherein the salt has at least about 95% crystalline purity.5. The therapeutic composition of claim 1 , wherein the salt is characterized claim 1 , when measured at about 25° C. with Cu—Kα radiation claim 1 , by the powder diffraction pattern shown in .6. The therapeutic composition of claim 1 , wherein the salt is characterized by respective lattice parameters claim 1 , a claim 1 , b claim 1 , and c of about 16.4460 Å claim 1 , 21.4010 Å claim 1 , and 5.3050 Å and β of about 109° in the monoclinic crystal system P 21/C or P 21/M space group claim 1 , when measured with Mo—Kα radiation at about 25° C.7. The therapeutic composition of claim 1 , wherein the salt has substantial chemical purity.8. The therapeutic composition of claim 7 , wherein the salt is about 97% chemically pure.9. The therapeutic composition of claim 7 , wherein the salt is about 100% chemically pure.10. The therapeutic composition of claim ...

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Номер записи: 71
18-04-2019 дата публикации

A PROCESS FOR THE PREPARATION OF A CATALYST AND A PROCESS FOR PRODUCING GLYCOLS USING THE CATALYST

Номер: US20190111413A1
Автор: COLIJN Hendrik Albertus, DE VLIEGER Dionysius Jacobus Maria
Принадлежит:

A process for the preparation of a catalyst composition for catalysing hydrogenation and hydrogenolysis reactions wherein, (a) a carbon support is contacted with a catalyst precursor solution comprising at least one element from groups 7, 8, 9, 10 and 11 of 5 the periodic table to form a metal impregnated carbon; (b) the metal impregnated carbon is dried at a temperature of no greater than 400° C. and placed in a reactor vessel; (c) the reactor vessel is sealed; and (d) the metal impregnated carbon is treated in the reactor 10 vessel in an atmosphere comprising hydrogen at a temperature of from 25° C. to 350 ° C. 1. A process for the preparation of a catalyst composition for catalysing hydrogenation and hydrogenolysis reactions wherein:(a) a carbon support is contacted with a catalyst precursor solution comprising at least one element from groups 7, 8, 9, 10 and 11 of the periodic table to form a metal impregnated carbon;(b) the metal impregnated carbon is dried at a temperature of no greater than 400° C. and placed in a reactor vessel;(c) the reactor vessel is sealed; and(d) the metal impregnated carbon is treated in the sealed reactor vessel in an atmosphere comprising hydrogen at a temperature of from 25° C. to 350° C. to form an activated catalyst composition.2. The process claimed in claim 1 , wherein catalyst precursor solution comprises ions of at least one element selected from a group consisting of ruthenium claim 1 , cobalt claim 1 , nickel claim 1 , palladium claim 1 , platinum claim 1 , iridium claim 1 , rhenium and copper.3. The process claimed in claim 1 , wherein the catalyst precursor solution comprises water.4. The process claimed in claim 1 , wherein the catalyst precursor solution comprises an alcohol or acetone.5. A process for the production of glycols comprising the step of:(a) preparing a catalyst composition in accordance with the process of any of preceding claims;(b) whilst the catalyst composition remains inside the reactor vessel in an ...

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Номер записи: 72
18-04-2019 дата публикации

Method for Increasing UV Transmittance of Ethylene Glycol

Номер: US20190112248A1
Автор: Haiyu Ren, Yi Yuan
Принадлежит: Changchun Meihe Science and Technology Development Co Ltd, Coca Cola Co

The present invention provides a method for increasing the UV transmittance of ethylene glycol. The method uses an ethylene glycol solution and hydrogen as raw materials, and uses an alloy catalyst comprising nickel, one or more rare-earth elements, tin, and aluminum, the contents thereof in parts by weight being 10-90, 1-5, 1-60, and 5-9, respectively. The method of the present invention uses an inexpensive, stable-in-aqueous-phase, carrier-free alloy as a catalyst, and continuously adds hydrogen to reduce unsaturated impurities in ethylene glycol. In application of the method of the present invention in continuous industrial-scale production, the use of this type of alloy catalyst could be especially significant for the achievement of long-term system stability and control of production costs.

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Номер записи: 73
25-04-2019 дата публикации

SINGLE COMPOSITION COMPRISING A DISINFECTANT AND A LUBRICANT COMBINED WITH A METHOD OF USING SAID COMPOSITION COMPRISING TO DISINFECT AND/OR LUBRICATE A FLUID ENCOMPASSING SYSTEM

Номер: US20190116846A1
Автор: OVERMYER MICHAEL, Overmyer Thad J.
Принадлежит:

A combination of a method using a composition utilized together to disinfect and/or lubricate a fluid encompassing system. A single composition comprising a disinfectant and a lubricant comprises water-alcohol-glycerin-chlorhexidine gluconate. 1. A single composition comprising a disinfectant combined with a method of using said composition comprising to disinfect a fluid encompassing system , which comprises i. about 25% to 75% by volume of water,', 'ii. about 5% to 35% by volume of alcohol,', 'iii. about 10% to 50% by volume of glycerin,', 'iv. about 0.06% to about 2.0% by volume of chlorhexidine gluconate;, 'a) fill said system in a composition comprising'}b) a method of comprising to disinfect and/or lubricate said system comprising of the following steps: purging said system, adding said composition into said system, and flushing/rinsing said system; andc) said single composition comprising a disinfectant and a lubricant combined with said method of using this composition comprising to disinfect and/or lubricate said fluid encompassing system and said system's fluid system components comprising of fluid conduit(s), and/or fluid reservoir(s), and/or valve(s), and/or device(s) that connect to this system's fluid system.2. A composition according to wherein this composition's ingredient claim 1 , water claim 1 , is treated by a ultra-violet light claim 1 , deionization claim 1 , filtration claim 1 , reverse osmosis claim 1 , and a water softening process in order to ensure this treated water is considered pure claim 1 , which maintains the efficacy of the chemical ingredients in this composition.3. A composition according to wherein the lubricant is other than a petroleum-based product.a) Glycerin lubricates this fluid encompassing system, which improves this system's operation and efficiency.4. A composition according to wherein the lubricant is a trihydric alcohol.5. A composition according to wherein the trihydric alcohol is glycerin.6. A composition according ...

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Номер записи: 74
12-05-2016 дата публикации

POLYMERS PREPARED FROM MEVALONOLACTONE AND DERIVATIVES

Номер: US20160130389A1
Автор: Dugar Deepak, Friedberger Tobias
Принадлежит:

Described herein polymer precursor compounds (aka polymer building blocks) of derived from biobased compounds, and specifically biobased mevalonolactone and its related derivatives. Through oxidation these biobased precursors can be reacted to yield building blocks for (unsaturated-) polyesters, polyester polyols and polyamides, as well as precursors for glycidyl esters and omega-alkenyl esters. Through reduction, these biobased precursors can be reacted to yield building blocks for (unsaturated-) polyesters, polyester polyols, polycarbonates, as well as precursors for glycidyl ethers and omega-alkenyl ethers. Through nucleophilic ring opening and/or amidation, these biobased precursors can be reacted to yield building blocks for polyester polyols, chain-extender for polyurethanes, or polyester-amides. 2. The compound of claim 1 , wherein each Y is —N(H) or —N(R).3. The compound of claim 1 , wherein each Ris selected from the group consisting of C-Calkyls.4. The compound of claim 1 , wherein Q is a linear hydrocarbyl selected from the group consisting of C-Calkyls.5. The compound of claim 1 , wherein said compound has a 14C/12C ratio greater than zero.6. A biobased polymer comprising recurring monomeric units synthesized from a compound according to .8. The compound of claim 1 , wherein each Ris selected from the group consisting of C-Calkyls.9. The compound of claim 7 , wherein said compound has a 14C/12C ratio greater than zero.10. A biobased polymer comprising recurring monomeric units synthesized from a compound according to .12. The compound of claim 11 , wherein each Y is —N(H) or —N(R).13. The compound of claim 11 , wherein each Ris selected from the group consisting of C-Calkyls.14. The compound of claim 11 , wherein Q is a linear hydrocarbyl selected from the group consisting of C-Calkyls15. The compound of claim 11 , wherein said compound has a 14C/12C ratio greater than zero.16. A biobased polymer comprising recurring monomeric units synthesized from a ...

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Номер записи: 75
10-05-2018 дата публикации

Process for preparing polyols

Номер: US20180127350A1
Автор: Eric Monflier, Frederic Hapiot, Théodore Vanbesien
Принадлежит: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, Pivert SAS, Universite dArtois

The present invention relates to a process for preparing polyols. In particular, the present invention relates to the preparation, in a single step, of polyols by a process involving a hydrohydroxymethylation reaction starting from a composition A comprising one or more compounds of formula (I).

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Номер записи: 76
21-05-2015 дата публикации

Method and apparatus for circulating a glycol stream, and method of producing a natural gas product stream

Номер: US20150135954A1
Автор: Bei Li, Johan Jan Barend Pek, Stephen John Mills
Принадлежит: Shell Oil Co

The methods apparatuses described herein involve recovering of glycol from an aqueous phase to form a stream of recovered glycol and a glycol recovery system. The aqueous phase is fed to the top of a lower theoretical stage in a distillation column. An overhead vapour stream is drawn from the distillation column overhead of an upper theoretical stage, and a bottom stream comprising a stream of regenerated glycol is drawn from the distillation column via a bottom outlet configured below the lower theoretical stage. The stream of recovered glycol comprises the regenerated glycol. In addition, a first middle theoretical stage is situated within the distillation column gravitationally above the lower theoretical stage and below the upper theoretical stage. A side stream of liquid water is drawn from the bottom of the upper theoretical stage in the distillation column.

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Номер записи: 77
10-05-2018 дата публикации

PROCESS FOR PREPARATION OF DAPAGLIFLOZIN

Номер: US20180127391A1
Автор: BHIRUD Shekhar Bhaskar, BHUSHAN Kumar Hari, Gaikwad Nandkumar, GORE Sharad, JAGDHANE Rajendra, Kulkarni Mandar, SURAPARAJU Raghu Ram
Принадлежит:

The present invention relates to a process for the preparation of amorphous dapagliflozin. The present invention relates to 2,3-butanediol solvate of dapagliflozin and process for its preparation. 4. The process of claim 1 , wherein in step (f) claim 1 , the alcohol is methanol and the ether is diisopropyl ether.5. The process of claim 1 , wherein in step (h) claim 1 , the alcohol is isopropyl alcohol and the hydrocarbon is cyclohexane.6. The process of claim 1 , wherein the step (i) of recovering dapagliflozin in amorphous form comprises:(i) removing the solvent from the solution obtained in step (h); or(ii) treating the solution of step (h) with an anti-solvent.7. The process of claim 6 , wherein the solvent is removed from the solution by concentrating the solution claim 6 , or completely evaporating the solvent claim 6 , or removing the solvent by one of lyophilisation claim 6 , freeze-drying claim 6 , spray drying claim 6 , fluid bed drying claim 6 , flash drying claim 6 , spin flash drying claim 6 , and thin-film drying.8. (canceled)10. The process of claim 9 , wherein the ether solvent is selected from the group consisting of diethyl ether claim 9 , diisopropyl ether claim 9 , methyl tert-butyl ether claim 9 , tetrahydrofuran claim 9 , and dioxane.11. The process of claim 9 , wherein the alcohol solvent is selected from the group consisting of methanol claim 9 , ethanol claim 9 , n-propyl alcohol claim 9 , and isopropyl alcohol.1224.-. (canceled) This application claims the benefit of Indian Provisional Applications 1790/MUM/2015 filed on May 5, 2015 and 201621002175 filed on Jan. 20, 2016, entitled “PROCESS FOR PREPARATION OF DAPAGLIFLOZIN”, the contents of which are incorporated herein by reference.The present invention relates to a process for the preparation of amorphous dapagliflozin. The present invention relates to 2,3-butanediol solvate of dapagliflozin and process for its preparation.Dapagliflozin, also known as D-glucitol, 1,5-anhydro-1-C-[4-chloro- ...

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Номер записи: 78
31-07-2014 дата публикации

PRODUCTION OF OPTICALLY PURE PROPANE-1,2-DIOL

Номер: US20140212957A1
Автор: Boerner Armin, Kuehlein Klaus, Schulze Joachim, Shuklov Ivan, Tietz Wolfgang
Принадлежит: THYSSENKRUPP INDUSTRIAL SOLUTIONS GMBH

A method for producing optically pure propane-1,2-diol, including the method steps: a. hydrogenation of lactides, metal-catalysed heterogenous catalysis being carried out in the presence of hydrogen, a crude product containing propane-1,2-diol being produced, and b. dynamic, kinetic racemate resolution, propane-1,2-diol of an optical purity in the range of ≧99% e.e. being produced. 1. Process for the production of optically pure propane-1 ,2-diol comprising the following process steps:Hydrogenation of lactides, wherein a metal-catalysed heterogeneous catalysis is carried out in the presence of hydrogen, a raw product containing propane-1,2-diol being produced, andDynamic kinetic racemic resolution, in which optically pure propane-1.2-diol is produced within a range of ≧99% e.e.2. Process in accordance with claim 1 , wherein the lactides are selected from the group comprising D claim 1 ,D-lactide claim 1 , L claim 1 ,L-lactide claim 1 , meso-lactide and L claim 1 ,L/D claim 1 ,D-lactide.3. The process in accordance with claim 1 , wherein the metal-catalysed heterogeneous catalysis in step a) is carried out in the liquid phase.4. Process in accordance with claim 3 , wherein the liquid phase is selected from a group of solvents comprising water claim 3 , aliphatic or aromatic hydrocarbons with a chain length of up to 10 C-atoms claim 3 , and mixtures thereof claim 3 , wherein the aliphatic hydrocarbons are preferably alcohols with particular preference being given to methanol and/or ethanol being used.5. The process in accordance with wherein the heterogeneous catalysis in step a) is carried out using a catalyst from the metals group claim 1 , wherein the metal is selected from a group comprising ruthenium claim 1 , rhodium claim 1 , rhenium claim 1 , palladium claim 1 , platinum claim 1 , nickel claim 1 , cobalt claim 1 , molybdenum claim 1 , wolfram claim 1 , titanium claim 1 , zirconium claim 1 , niobium claim 1 , vanadium claim 1 , chromium claim 1 , manganese ...

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Номер записи: 79
19-05-2016 дата публикации

Biosynthesis of 1,3-Butanediol

Номер: US20160138052A1
Автор: Mordaka Pawel
Принадлежит:

This document describes biochemical pathways for producing 1,3-butanediol using a polypetide having β-ketothiolase activity to form a 3-oxo-5-hydroxypentanoyl-CoA intermediate that can be enzymatically converted to 1,3-butanediol, as well as recombinant hosts producing 1,3-butanediol. 1. A method of producing 3-oxo-5-hydroxypentanoyl-CoA , said method comprising:enzymatically converting 3-hydroxypropionyl-CoA to 3-oxo-5-hydroxypentanoyl-CoA using a polypeptide having β-ketothiolase activity classified under EC. 2.3.1.-.2. The method of claim 1 , whereinsaid polypeptide having β-ketothiolase activity is classified under EC 2.3.1.16. or EC 2.3.1.174.3. (canceled)4. The method of claim 1 , wherein said polypeptide having β-ketothiolase activity has at least 70% sequence identity to the amino acid sequence set forth in SEQ ID NOs: 1 claim 1 , 2 claim 1 , 7 or 13.5. The method of claim 1 , further comprising:enzymatically converting 3-oxo-5-hydroxypentanoyl-CoA to 1,3-butanediol using a thioesterase or a CoA transferase, a decarboxylase, and a secondary alcohol dehydrogenase.6. The method of claim 5 , wherein said thioesterase is classified under EC 3.1.2.- claim 5 , said CoA transferase is classified under EC 2.8.3.- claim 5 , said decarboxylase is classified under EC 4.1.1.4 or said secondary alcohol dehydrogenase is classified under EC 1.1.1.B3 claim 5 , EC 1.1.1.B4 claim 5 , or EC 1.1.1.80.7. The method of claim 5 , wherein said thioesterase has at least 70% sequence identity to the amino acid sequence set forth in SEQ ID NO: 3 or 14; said CoA transferase has at least 70% sequence identity to the amino acid sequence set forth in SEQ ID NO: 5 or 6; said decarboxylase has at least 70% sequence identity to the amino acid sequence set forth in SEQ ID NO: 8 or 10; or said secondary alcohol dehydrogenase has at least 70% sequence identity to the amino acid sequence set forth in SEQ ID NO: 4 claim 5 , 9 claim 5 , or 11.820-. (canceled)21. The method of claim 1 , wherein ...

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Номер записи: 80
08-09-2022 дата публикации

Cycle water treatment process for ethlyene epoxidation

Номер: US20220281757A1
Автор: Jason P. Durand, Saurabh H. PARIKH, Saurabh KATIYAR
Принадлежит: Scientific Design Co Inc

A method for the oxidation of ethylene to form ethylene oxide which comprises treating an aqueous stream in a cycle water treatment unit containing an anion exchange resin to reduce the content of the impurities.

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Номер записи: 81
30-04-2020 дата публикации

Multi-arm single molecular weight polyethylene glycol, active derivative thereof, and preparation and application thereof

Номер: US20200131109A1
Автор: Meina Lin, Xuan Zhao, Zhen Wei
Принадлежит: Tianjin Jenkem Technology Co Ltd

Being used for drug modification, the multi-arm single molecular weight polyethylene glycol and an active derivative thereof provided herein can effectively improve the solubility, stability, and immunogenicity of the drugs, improve the absorption of the drugs in vivo, prolong the half-life of the drugs, and increase bioavailability, enhance efficacy, and reduce toxic and side effects of the drugs. A gel formed from the active derivative of the multi-arm single molecular weight polyethylene glycol provided herein can be used for the preparation of controlled release drugs so as to prolong the action time of the drugs, thereby reducing the number of administrations and improving patient compliance.

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Номер записи: 82
28-05-2015 дата публикации

Amidinate and Guanidinate Complexes, Their Use as Chain Transfer Polymerization Catalysts and Long Chain Alcohols Obtained by Such Process

Номер: US20150148505A1
Автор: Gross Thoralf, Hubner Christian, Kempe Rhett, Kretschmer Winfried, Ziehe Holger
Принадлежит:

The present invention is concerned with a catalyst composition comprising titanium-, zirconium- and/or hafnium amidinate complexes and/or titanium-, zirconium- and/or hafnium guanidinate complexes and organo aluminium and/or organic zinc compounds, a coordinative chain transfer polymerization (CCTP) process employing the catalyst composition as well as long chain aluminium alkyls and subsequent alcohols obtained by such process. 2. The composition of wherein the metal is Ti or Zr.4. The composition of wherein the metal complex is formed in situ from a transition metal precursor and a ligand precursor.5. The composition of wherein the organo aluminium compound is used together with an organo zinc compound as co-catalyst.6. The composition of wherein for the guanidate Z1 and Z3 independently from each other are selected from an ortho-substituted aromatic moiety and a di-ortho substituted aromatic moiety.7. The composition of wherein at least one of Z1 and Z3 is claim 6 , independently of each other claim 6 , di-ortho-methyl-phenyl claim 6 , di-ortho-ethyl phenyl claim 6 , di-ortho-isopropyl phenyl claim 6 , or di-ortho-t-butyl phenyl.8. The composition of wherein the composition comprises additionally a boron containing compound as activator and the boron containing compound preferably comprises one or more members selected from the group consisting of tris(pentafluoro phenyl) borane claim 1 , tetrakis(pentafluoro phenyl)borate claim 1 , tris(tetrafluoro phenyl) borane and tetrakis(tetrafluoro phenyl)borate.9. The composition of wherein the co-catalyst is triethyl aluminium.10. The composition of wherein the catalyst is the guanidate.11. The composition of wherein the co-catalyst is a mixture of the aluminium-compound and the zinc-compound claim 5 , the zinc-compound being dihydrocarbyl zinc ZnRwith R=C1-C8 claim 5 , and the ratio being 100:1 to 1:100.12. The composition of wherein the ratio of the catalyst to the co-catalyst is from 1:10000 to 1:100000 claim 1 , ...

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Номер записи: 83
28-05-2015 дата публикации

MICROORGANISMS AND METHODS FOR PRODUCTION OF 4-HYDROXYBUTYRATE, 1,4-BUTANEDIOL AND RELATED COMPOUNDS

Номер: US20150148513A1
Автор: Burgard Anthony P., Burk Mark J., KUCHINSKAS Michael P., Osterhout Robin E., Pharkya Priti, STEER Brian, Trawick John D., VAN DIEN Stephen J.
Принадлежит: GENOMATICA, INC.

The invention provides non-naturally occurring microbial organisms having a 4-hydroxybutyrate, 1,4-butanediol, or other product pathway and being capable of producing 4-hydroxybutyrate, 1,4-butanediol, or other product, wherein the microbial organism comprises one or more genetic modifications. The invention additionally provides methods of producing 4-hydroxybutyrate, 1,4-butanediol, or other product or related products using the microbial organisms. 1. A non-naturally occurring microbial organism , said microbial organism having a 4-hydroxybutyrate pathway and being capable of producing 4-hydroxybutyrate , wherein said microbial organism comprises a genetic modification , said genetic modification selected from:(A) a genetic modification that increases expression of phosphoenolpyruvate carboxylase;(B) a genetic modification that increases expression of alpha-ketoglutarate dehydrogenase;(C) a genetic modification that increases expression of a non-phosphotransferase (PTS) glucose uptake system;(D) a genetic modification that increases expression of a gamma-butyrolactone esterase;(E) a genetic modification that decreases expression of succinyl-CoA synthetase;(F) a genetic modification that decreases expression of an acyl coenzyme A thioesterase;(G) a genetic modification that decreases expression of an alcohol dehydrogenase;(H) a genetic modification that decreases expression of a non-energy-producing NADH dehydrogenase;(I) a genetic modification that decreases expression of a cytochrome oxidase; and(J) a combination of two or more, three or more, four or more, five or more, six or more, seven or more, eight or more, or all of the genetic modifications of parts (A)-(I).2. The microbial organism of claim 1 , wherein said microbial organism of parts (D) or (F) further comprises a 4-hydroxybutyryl-CoA pathway.3. The microbial organism of claim 1 , wherein said microbial organism further comprises a 1 claim 1 ,4-butanediol pathway.4. The microbial organism of claim 1 , ...

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Номер записи: 84
30-04-2020 дата публикации

Coating composition for forming resist underlayer film for euv lithography process

Номер: US20200133126A1
Автор: Jae Hwan SIM, Jae-Bong Lim, Jin Hong Park, Myung Yeol Kim, Suwoong Kim, Yoo-Jin Ghang
Принадлежит: Rohm and Haas Electronic Materials Korea Ltd

A monomer represented by Chemical Formula (1): wherein, X, Y, and Z are the same as described in the specification, and the polymer including repeat units derived from the monomer.

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Номер записи: 85
07-05-2020 дата публикации

SILICALITE-1 MOLECULAR SIEVE-BASED CATALYST AND PREPARATION METHOD FOR 1,2-PENTANEDIOL USING SAID CATALYST

Номер: US20200139353A1
Автор: BIAN Xinjian, Chen Changsheng, Ding Ke, HU Jianglin, Hua Weiqi, Jiang Qingmei, Li Yuan, Liu Yunhai, SONG Yanfang, Wang Kun, YANG Hengdong, Yang Yang, Zeng Wei
Принадлежит:

An organic-base functionalized silicalite-1 molecular sieve-encapsulated metal nanoparticles catalyst and a preparation method therefor, as well as a method for preparing 1,2-pentanediol from biomass-derived furfuryl alcohol by hydrogenolysis using said catalyst. When the catalyst is used in a reaction preparing 1,2-pentanediol from furfuryl alcohol by hydrogenolysis, the catalyst has high hydrogenolysis activity under relatively mild reaction conditions, significantly increasing the conversion rate of furfuryl alcohol and 1,2-pentanediol selectivity in the reaction, while also not generating obvious byproducts furfuryl alcohol polymers; the catalyst has good stability and long life, and may be recovered for reuse after the reaction is complete by means of a simple filtration, greatly reducing reaction costs and separation difficulty. 1. A catalyst for preparing 1 ,2-pentanediol by hydrogenolysis of furfuryl alcohol , wherein the catalyst comprises a carrier and an active component , the carrier is a silicalite-1 molecular sieve surface-modified with an organic-base silane coupling agent , the active component is metal nanoparticles encapsulated in the pores of the silicalite-1 molecular sieve.3. The catalyst according to claim 1 , wherein the metal nanoparticle is one or more of Ni claim 1 , Co claim 1 , Cu claim 1 , Ru claim 1 , Rh claim 1 , Pd claim 1 , Ir claim 1 , Pt and Au claim 1 , preferably Pt and/or Au.4. The catalyst according to claim 1 , wherein the loading amount of the metal nanoparticle is 0.01-5 wt % claim 1 , based on the mass of the silicalite-1 molecular sieve without surface-modification in the catalyst.5. The catalyst according to claim 4 , wherein the amount of the organic-base silane coupling agent is 0.01-5 mmol/g claim 4 , based on the mass of the silicalite-1 molecular sieve without surface-modification in the catalyst.6. A method for preparing the catalyst according to claim 1 , wherein the method comprises the steps of:a) reducing an ...

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Номер записи: 86
07-05-2020 дата публикации

Method for Catalytically Hydrogenating Oxalates

Номер: US20200140359A1
Автор: Lv Jing, MA Xinbin, Wang Shengping, Wang Yue, Yao Dawei, Zhao Yujun
Принадлежит:

The invention discloses a method for catalytically hydrogenating oxalates. In the method, an oxalate and hydrogen gas are contacted with a nanotube assembled hollow sphere catalyst, to produce a product comprising glycolate or glycol. The predominant chemical components of the catalyst include copper and silica, in which the copper is in an amount of 5 to 60% by weight of the catalyst, and the silica is in an amount of 40-95% by weight of the catalyst. The catalyst has a specific surface area of 450-500 m/g, an average pore volume of 0.5-1 cm/g, and an average pore diameter of 5-6 nm. The catalyst is in a structure of assembling nanotubes on hollow spheres, wherein the hollow spheres have a diameter of 50-450 nm, and a wall thickness of 10-20 nm, and the nanotubes, vertically arranged on the surfaces of the hollow spheres, have a diameter of 3-5 nm, and a length of 40-300 nm. Even in the case of a low H/DMO feeding ratio, the method of the invention still can exhibit an excellent activity of hydrogenating oxalates and an excellent selectivity to ethylene glycol, and reduce circulation quantity of hydrogen gas, thereby to save power costs and apparatus costs, and it can flexibility adjust the selectivity of ethylene glycol and glycolate. Thus, the method has high industry prospects and application values. 1. A method for catalytically hydrogenating an oxalate , characterized in that: the oxalate and hydrogen gas are contacted with a nanotube assembled hollow sphere catalyst , to produce a product comprising glycolate or ethylene glycol , wherein the predominant chemical components of the catalyst include copper and silica , in which the copper is in an amount of 5 to 60% by weight of the catalyst , and the silica is in an amount of 40-95% by weight of the catalyst; the catalyst has a specific surface area of 450-500 mg , an average pore volume of 0.5-1 cm/g , and an average pore diameter of 5-6 nm; the catalyst is in a structure of assembling nanotubes on hollow ...

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Номер записи: 87
11-06-2015 дата публикации

PREVENTION OR SUPPRESSION OF CYRSTALLISATION OF BORIC ACID PRESENT IN AN AQUEOUS PHASE

Номер: US20150158810A1
Автор: Autissier Laurence, Briere Alix, Longuet Laurence
Принадлежит:

The invention relates to the use of at least one compound comprising at least two hydroxyl functions, the compound being selected from alcohols, aminoalcohols, carboxylic acids and hydroxyacids, for preventing the crystallization of boric acid present in an aqueous phase, or for suppressing this crystallization when this crystallization has already been initiated. 1. A method comprising:using at least one compound comprising at least two hydroxyl functions, the compound being selected from alcohols, aminoalcohols, carboxylic acids, and hydroxyacids, to prevent crystallization of boric acid present in an aqueous phase, or to suppress said crystallization when crystallization has already been initiated.2. The method according to claim 1 , wherein the compound comprising at least two hydroxyl functions includes a total number of carbon atoms which is at most equal to eight.3. The method according to claim 2 , wherein the compound comprising at least two hydroxyl functions includes from 2 to 6 hydroxyl functions.4. The method according to claim 3 , wherein the compound comprising at least two hydroxyl functions is selected from maleic acid claim 3 , 2 claim 3 ,2-dimethylpropane-1 claim 3 ,3-diol claim 3 , 2-amino-2-(hydroxymethyl)-propane-1 claim 3 ,3-diol claim 3 , 2-[bis-(2-hydroxyethyl)-amino]-2-(hydroxymethyl)-propane-1 claim 3 ,3-diol claim 3 , myo-inositol claim 3 , and pentaerythritol.5. The method according to claim 4 , wherein the compound comprising at least two hydroxyl functions is selected from 2-amino-2-(hydroxymethyl)-propane-1 claim 4 ,3-diol claim 4 , 2-[bis-(2-hydroxyethyl)-amino]-2-(hydroxymethyl)-propane-1 claim 4 ,3-diol claim 4 , and pentaerythritol.6. The method according to any of the preceding claim 1 , wherein a mass concentration of boric acid in the aqueous phase is at least equal to a value of a mass solubility of boric acid at a temperature which is exhibited by said aqueous phase containing boric acid.7. The method according to claim 1 , ...

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Номер записи: 88
21-08-2014 дата публикации

Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses

Номер: US20140235723A1
Автор: Carmen Daniela Oniciu, Jean-Louis Henri Dasseux
Принадлежит: Esperion Therapeutics Inc

The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

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Номер записи: 89
22-09-2022 дата публикации

1,3-butylene glycol product

Номер: US20220296481A1
Автор: Keisuke Ono, Midori UMEHARA, Tetsuro NAKANISHI, Yasuteru Kajikawa, Yuki TESHIMA, Yuuichirou Hirai
Принадлежит: Daicel Corp

Provided is a high-purity 1,3-butylene glycol product that is colorless and odorless, unlikely to be colored over time, and furthermore, unlikely to cause acid concentration increase over time in a state containing water. A 1,3-butylene glycol product, having, according to a gas chromatographic analysis performed under predetermined conditions, a peak ratio of 2000 ppm or lower appearing in a relative retention time ranging from 1.6 to 1.8, provided that the relative retention time for a peak of 1,3-butylene glycol is 1.0.

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Номер записи: 90
07-06-2018 дата публикации

CATALYST SUPPORT AND RELATED PROCESSES

Номер: US20180155458A1
Автор: Barbosa Cesar Augusto Sales, Cardoso Renata da Silva, Fernandes Jonas Alves, Washburger Marcia Regina
Принадлежит: Braskem S.A.

The present invention describes a catalyst support, which is used as an inorganic carrier for a Ziegler-Nata catalyst (ZN), using a modified spray cooling method. Such a catalyst support is prepared from alcoholic solutions of (a) an inorganic compound, in which the inorganic compound is a magnesium compound and (b) an inorganic compound and one or more additives. The solutions are prepared at a temperature below 100° C., carried through a nozzle placed inside a reactor, and sprayed into droplets forming a solid precipitate, which is generally spherical, when in contact with an inert hydrocarbon solvent at low temperature. The obtained catalyst support is reacted with a titanium compound, preferably titanium tetrachloride, in order to produce an active catalyst for olefin polymerization. 1. A catalyst support component comprising an inorganic compound , an alcohol ROH , and an additive.2. The catalyst support component of claim 1 , having at least a first thermal transition peak between 112° C. and 150° C. as shown by DSC.3. The catalyst support component of claim 1 , wherein the alcohol ROH consists of a R chosen from a C1-C18 hydrocarbon group.4. The catalyst support component of claim 1 , wherein the additive is a non-polymeric additive.5. The catalyst support component of claim 4 , wherein the non-polymeric additive is a fluorine-based additive.6. The catalyst support component of claim 1 , wherein the additive is selected from one or more of hydrofluoroalkenes (HFAs) claim 1 , polyaryletherketone (PAEK) derivatives claim 1 , poly(oxy-1 claim 1 ,2-ethanediyl) derivatives claim 1 , aliphatic polyethers claim 1 , polylactic acid claim 1 , or polysorbates.7. The catalyst support component of claim 5 , wherein the additive is fluorine-based and selected from the group consisting of perfluoropentane; 1 claim 5 ,1 claim 5 ,1 claim 5 ,2-tetrafluorethane; 1 claim 5 ,1 claim 5 ,1 claim 5 ,2 claim 5 ,3 claim 5 ,3 claim 5 ,3-heptafluoropentane; 1 claim 5 ,1 claim 5 ,1 ...

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Номер записи: 91
22-09-2022 дата публикации

Process for the production of 1,4-butanediol from renewable sources and polyesters obtained therefrom

Номер: US20220298090A1
Автор: Catia Bastioli, Luigi Capuzzi, Marco Cotti Comettini, Roberto Vallero
Принадлежит: Novamont SpA

The invention relates to a process for the production of 1,4-butanediol comprising the preparation of a fermentation broth comprising 1,4-butanediol from renewable sources and water, separation of a liquid fraction comprising said 1,4-butanediol and water from one or more solid fractions, said liquid fraction comprising 2-pyrrolidone in an amount higher than 80 ppm, one or more passages of the resulting liquid fraction through a bed comprising one or more cation-exchange resins thereby providing an output pH of said liquid fraction from 4 to 2, one or more passages of the resulting liquid fraction through a bed comprising one or more anion-exchange resins thereby providing an output pH of said liquid fraction from 8 to 11, and the distillation of the liquid fraction thereby provided so as to obtain a composition having a concentration of said 1,4-butanediol higher than 99.0% by weight and comprising 2-pyrrolidone in an amount lower than 6 ppm. The resulting composition should exhibit an APHA color value after ageing of less than 30.

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Номер записи: 92
08-06-2017 дата публикации

METHOD FOR PREPARING ERIBULIN INTERMEDIATE

Номер: US20170158705A1
Автор: GUAN Zhongjun, LEI Shenghui, ZHANG Fuyao, ZHANG Xinning
Принадлежит: UNITRIS BIOPHARMA CO., LTD.

Intermediates used in the synthesis of Eribulin and methods for preparing the intermediates are described. For example, a compound of formula IV and a method for preparing the compound are described, wherein Ris a hydroxyl protecting group, preferably a (Calkyl group or aryl group)silyl group, and more preferably tert-butyldiphenylsilyl (TBDPS); and Ris a hydroxyl protecting group, preferably a benzyl group or (Calkyl group or aryl group)silyl group, and more preferably a benzyl group or tert-butyldimethylsilyl (TBS). A method for preparing Eribulin using the intermediates is also provided. The method has the advantages of moderate reaction conditions, is simple to execute and low cost, and is thus suitable for mass production. 3. (canceled)10. (canceled)13. (canceled)14. A method for preparing eribulin claim 5 , comprising preparing a compound of formula II according to the method of claim 5 , and then preparing eribulin from the compound of formula II.15. The compound of formula IV according to claim 1 , wherein Ris a (Calkyl or aryl)silyl group; and Ris benzyl or a (Calkyl or aryl)silyl group.16. The compound of formula V according to claim 1 , wherein Ris a (Calkyl or aryl)silyl group; and Ris benzyl or a (Calkyl or aryl)silyl group.17. The compound of formula IV or formula V according to claim 1 , wherein Ris tert-butyldiphenylsilyl (TBDPS); and Ris benzyl or tert-butyldimethylsilyl (TBS).18. The compound of formula VI according to claim 8 , wherein Ris a (Calkyl or aryl)silyl group; and Ris benzyl or a (Calkyl or aryl)silyl group.19. The compound of formula VII according to claim 8 , wherein Ris a (Calkyl or aryl)silyl group; and Ris benzyl or a (Calkyl or aryl)silyl group.20. The compound of formula VI or formula VII according to claim 8 , wherein Ris a tert-butyldiphenylsilyl (TBDPS); and Ris benzyl or tert-butyldimethylsilyl (TBS).21. The method according to claim 12 , wherein Ris tert-butyldiphenylsilyl (TBDPS); and Ris benzyl. The present invention ...

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Номер записи: 93
24-06-2021 дата публикации

SORBENT COMPOSITIONS FOR THE REMOVAL OF BORON FROM AQUEOUS MEDIUMS

Номер: US20210188665A1
Автор: Cayton Roger H., Huston Robert B., Mitchek Micala D., Song Lingyan
Принадлежит:

Sorbent compositions that includes a base sorbent material having a high porosity and surface area and a boron-selective agent are particularly useful for the sequestration of boron from waste materials such as coal combustion residual leachate (CCRs). By using a boron-selective agent in conjunction with a high surface area base sorbent material such as activated carbon or biochar, a sorbent composition with a high capacity for sequestering boron at relatively low cost is provided. 145.-. (canceled)46. A method of treating an aqueous medium , comprising contacting an aqueous medium comprising a boron contaminate with a base sorbent material in the presence of a boron selective agent , wherein the base sorbent material captures at least a portion of the boron contaminate.47. The method recited in claim 46 , wherein the boron-selective agent comprises a compound selected from the group of compounds comprising 1 claim 46 ,2 hydroxyl groups claim 46 , 1 claim 46 ,2 carboxyl groups claim 46 , 1 claim 46 ,2 carbonyl groups claim 46 , 1 claim 46 ,3 hydroxyl groups claim 46 , 1 claim 46 ,3 carboxyl groups claim 46 , 1 claim 46 ,3 carbonyl groups claim 46 , and combinations thereof.48. The method recited in claim 47 , wherein the compound also has a functional group selected from the group consisting of an imino group claim 47 , an amino group claim 47 , and combinations thereof.49. The method recited in claim 46 , wherein the boron-selective agent comprises a compound selected from the group consisting of sorbitol claim 46 , mannitol claim 46 , polyvinyl alcohol (PVA) claim 46 , 1 claim 46 ,2 ethanediol claim 46 , 1 claim 46 ,2 propanediol claim 46 , catechol claim 46 , tannic acid claim 46 , glucose claim 46 , mannose claim 46 , glycerol claim 46 , ribose claim 46 , cellulose claim 46 , curcumin claim 46 , citric acid claim 46 , tartaric acid claim 46 , malic acid claim 46 , salicyl alcohol claim 46 , 1 claim 46 ,3 propanediol claim 46 , bis(hydroxymethyl)phenol claim 46 , ...

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Номер записи: 94
24-06-2021 дата публикации

METHOD FOR CONTINUOUS PRODUCTION OF 2,3-BUTANEDIOL

Номер: US20210188746A1
Автор: DÍAZ DE GUEREÑU ZABARTE María Del Mar, OCHOA GÓMEZ José Ramón, PÉREZ GIL Susana, RINCÓN ARROYO Inés
Принадлежит:

The present invention relates to a method for continuous production of 2,3-butanediol by hydrogenation of 3-hydroxybutanone with hydrogen in the presence of a heterogeneous hydrogenation catalyst filled in one or more fixed-bed flow tubular reactor systems comprising one or more tubes with an inner diameter from 1 mm to 6 mm. 1. A method for continuous production of 2 ,3-butanediol , by hydrogenation of 3-hydroxybutanone with hydrogen in the presence of a heterogeneous hydrogenation catalyst filled in one or more fixed-bed flow tubular reactor systems comprising one or more tubes , wherein the inner diameter of each tube is from 1 mm to 6 mm; wherein the method comprising feeding 3-hydroxybutanone and hydrogen into the fixed-bed flow tubular reactor system.2. The method according to claim 1 , wherein the number of tubes in each reactor system is from 1 to 25 claim 1 ,000.3. The method according to claim 1 , wherein the fixed-bed flow tubular reactor system comprises two or more parallel tubes having the same lengths and internal diameters.4. The method according to claim 1 , wherein the inner diameter of each tube is from 1.5 mm to 4 mm.5. The method according to claim 1 , wherein the length of each tube is from 5 cm to 5 m.6. The method according to claim 1 , wherein the method comprises feeding 3-hydroxybutanone into the reactor system as a liquid.7. The method according to claim 1 , wherein the method comprises feeding 3-hydroxybutanone into the reactor system as a solution in a solvent selected from the group consisting of water claim 1 , (C-C)-alkyl alcohol claim 1 , and mixtures thereof.8. The method according to claim 7 , wherein the (C-C)-alkyl alcohol is selected from the group consisting of methanol claim 7 , ethanol claim 7 , propanol claim 7 , 2-propanol claim 7 , 1-butanol claim 7 , 2-butanol claim 7 , sec-butanol and tert-butanol.9. The method according to claim 1 , wherein the reaction temperature is from 75° C. to 275° C.10. The method according to ...

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Номер записи: 95
14-06-2018 дата публикации

Ceramic printing ink composition having antibacterial function

Номер: US20180163065A1
Автор: Park Chung Kwon
Принадлежит:

The present invention relates to a ceramic printing ink composition having antibacterial function, and more particularly to a ceramic printing ink composition which is prepared by mixing deionized water, propylene glycol, propylene glycol methyl ether acetate (PMA) solvent, propylene glycol methyl ether (PM) solvent, isopropyl alcohol (IPA), a dispersing agent, a pigment. In a process of printing a pattern using the ceramic printing ink composition, the pattern is printed between or on ceramic coating layers by pad, screen or stamp printing. More specifically, ceramic coating (sol-gel) layers (1-coat, 2-coat, 3-coat, etc.) are formed and set-to-touch, after which the ceramic printing ink composition is coated on the coating layer and heated and cured simultaneously with the coating layers. Thus, bonding and adhesive strength of the ceramic printing ink composition is enhanced to enable printing to be more stably and easily performed on the ceramic coating layer. 1. A ceramic printing ink composition having an antibacterial function , the composition comprising an aqueous antibacterial composition.2. The ceramic printing ink composition according to claim 1 , wherein the composition comprises 10 to 25 wt % of deionized water claim 1 , 4 to 13 wt % of propylene glycol claim 1 , 0.5 to 4 wt % of PMA solvent claim 1 , 0.4 to 4 wt % of PM solvent claim 1 , 2 to 5 wt % of IPA claim 1 , 0.1 to 2 wt % of a dispersing agent claim 1 , 15 to 35 wt % of a pigment claim 1 , 5 to 65 wt % of a rheology modifier claim 1 , and 3 to 7 wt % of the aqueous antibacterial composition.3. The ceramic printing ink composition according to claim 1 , wherein the aqueous antibacterial composition is prepared by adding and dispersing 45 to 55 parts by weight of silica nanotubes claim 1 , 30 to 40 parts by weight of a wetting/dispersing agent claim 1 , 30 to 40 parts by weight of a co-solvent claim 1 , and 4 to 6 parts by weight of an antifoaming agent in 100 parts by weight of deionized water ...

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Номер записи: 96
21-05-2020 дата публикации

MICROORGANISMS AND METHODS FOR PRODUCTION OF SPECIFIC LENGTH FATTY ALCOHOLS AND RELATED COMPOUNDS

Номер: US20200157585A1
Автор: Burgard Anthony P., Osterhout Robin E.
Принадлежит:

The invention provides non-naturally occurring microbial organisms containing a fatty alcohol, fatty aldehyde or fatty acid pathway, wherein the microbial organisms selectively produce a fatty alcohol, fatty aldehyde or fatty acid of a specified length. Also provided are non-naturally occurring microbial organisms having a fatty alcohol, fatty aldehyde or fatty acid pathway, wherein the microbial organisms further include an acetyl-CoA pathway. In some aspects, the microbial organisms of the invention have select gene disruptions or enzyme attenuations that increase production of fatty alcohols, fatty aldehydes or fatty acids. The invention additionally provides methods of using the above microbial organisms to produce a fatty alcohol, a fatty aldehyde or a fatty acid. 126.-. (canceled)28. The non-naturally occurring microbial organism of claim 27 , wherein said microbial organism comprises:(a) two, three, or four exogenous nucleic acids each encoding an enzyme of said MI-FAE cycle;(b) two, three, or four exogenous nucleic acids each encoding an enzyme of said termination pathway; or(c) exogenous nucleic acids encoding each of the enzymes of at least one of the pathways selected from (1)-(13).29. The non-naturally occurring microbial organism of claim 27 , wherein said at least one exogenous nucleic acid is a heterologous nucleic acid.30. The non-naturally occurring microbial organism of claim 27 , wherein said microbial organism further comprises an acetyl-CoA pathway and at least one exogenous nucleic acid encoding an acetyl-CoA pathway enzyme expressed in a sufficient amount to produce acetyl-CoA claim 27 , wherein said acetyl-CoA pathway comprises a pathway selected from:(1) 2A and 2B;(2) 2A, 2C, and 2D;(3) 2H;(4) 2G and 2D;(5) 2E, 2F and 2B;(6) 2E and 21;(7) 2J, 2F and 2B;(8) 2J and 2I;(9) 3A, 3B, and 3C;(10) 3A, 3B, 3J, 3K, and 3D;(11) 3A, 3B, 3G, and 3D;(12) 3A, 3F, and 3D;(13) 3N, 3H, 3B and 3C;(14) 3N, 3H, 3B, 3J, 3K, and 3D;(15) 3N, 3H, 3B, 3G, and 3D;(16) ...

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Номер записи: 97
11-09-2014 дата публикации

METHODS FOR PRODUCING BIODERIVED PROPYLENE GLYCOL

Номер: US20140256991A1
Автор: Adlaf Kevin J., Bloom Paul D., Hoffman William Chris, Ma Chicheng, Soper John G., Zenthoefer Brad
Принадлежит: ARCHER DANIELS MIDLAND COMPANY

In the process of distilling a polyol product mixture including one or both of a biobased propylene glycol and a biobased ethylene glycol from the reaction of hydrogen with a biobased feed, it has been discovered that undesirable epoxides can form, and the present invention provides means for guarding against their formation, for removing epoxides which do form by particular methods of distilling, and for removing the epoxides from a finished, otherwise commercially acceptable biobased glycol product.

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Номер записи: 98
30-05-2019 дата публикации

Water-based vehicle for electroconductive paste

Номер: US20190164661A1
Автор: Lixin Song
Принадлежит: Heraeus Precious Metals North America Conshohocken LLC

The invention relates to a water-based vehicle used in the manufacture of an electroconductive silver paste. The water-based vehicle comprises a binder, a stabilizer, and water. The preferred embodiment of the invention utilizes at least one of polyvinylpyrrolidone, polyvinyl alcohol, and polyethelene glycol as the binder; and ethylene glycol as the stabilizer. Another aspect of the invention relates to an electroconductive paste composition based on the water-based vehicle. The preferred embodiment utilizes a metallic particle, a glass frit, and a water-based vehicle comprising a binder, a stabilizer, and water. The electroconductive paste of a high metallic content exhibits excellent storage stability.

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Номер записи: 99
01-07-2021 дата публикации

METHODS AND COMPOSITIONS INCORPORATING ALKYL POLYGLYCOSIDE SURFACTANT FOR USE IN OIL AND/OR GAS WELLS

Номер: US20210198177A1
Автор: Hill Randal M., Trabelsi Siwar
Принадлежит: Flotek Chemistry, LLC

Methods and compositions comprising an emulsion or a microemulsion for use treating an oil and/or gas well are provided. In some embodiments, the emulsion or the microemulsion comprises an aqueous phase, a solvent, a surfactant comprising alkyl polyglycoside, an alcohol, and, optionally, one or more additives. 1. A composition for use in an oil and/or gas well having a wellbore , comprising a microemulsion , wherein the microemulsion comprises:an aqueous phase;a surfactant comprising alkyl polyglycoside;a solvent comprising a terpene, a linear oleaginous hydrocarbon solvent, a branched oleaginous hydrocarbon solvent, a cyclic oleaginous hydrocarbon solvent, a saturated oleaginous hydrocarbon solvent, an unsaturated oleaginous hydrocarbon solvent, or a combination thereof; andan alcohol having from 1 to 8 carbon atoms.2. The composition of claim 1 , wherein the alcohol comprises butanol claim 1 , pentanol claim 1 , amyl alcohol claim 1 , butyl 3-hydroxybutanoate claim 1 , or combinations thereof.3. The composition of claim 1 , wherein the alcohol comprises amyl alcohol claim 1 , butyl 3-hydroxybutanoate claim 1 , or a combination thereof.4. The composition of claim 3 , wherein the solvent comprises a first solvent comprising a terpene and a second solvent comprising a linear oleaginous hydrocarbon solvent claim 3 , a branched oleaginous hydrocarbon solvent claim 3 , a cyclic oleaginous hydrocarbon solvent claim 3 , a saturated oleaginous hydrocarbon solvent claim 3 , an unsaturated oleaginous hydrocarbon solvent claim 3 , or combinations thereof.5. The composition of claim 4 , wherein the terpene comprises dipentene and/or d-limonene.6. The composition of claim 5 , wherein the terpene comprises dipentene and d-limonene.7. The composition of claim 1 , wherein the solvent comprises a first solvent comprising a terpene and a second solvent comprising a linear oleaginous hydrocarbon solvent claim 1 , a branched oleaginous hydrocarbon solvent claim 1 , a cyclic oleaginous ...

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Номер записи: 100