25-07-2013 дата публикации
Номер: US20130190289A1
Автор:
Chan Chun Kong Laval,
Collier Philip N.,
Court John J.,
Das Sanjoy Kumar,
Dorsch Warren,
Green Jeremy,
Lauffer David J.,
Li Pan,
Poisson Carl,
Tang Qing,
Waal Nathan,
Wilson Dean M.
A compound is represented by Structural Formula (I): 2. (canceled)47-. (canceled)8. The compound of claim 3 , wherein:{'sup': '1', 'sub': 1-6', '1', '6, 'Ris Calkyl optionally substituted with one or more substituents selected from the group consisting of halogen, —CN, —OH, and —O(C-Calkyl);'}{'sup': '2', 'sub': 5', '8', '2', '1', '6', '1', '6', '2', '1', '6', '1', '6', '2', '2', '1', '6', '1', '6', '1', '6', '1', '6', '2', '1', '6', '1', '6', '1', '6', '1', '6', '2', '2', '1', '6', '1', '6', '1', '6', '3-7', '3-7, 'Ris C-Ccycloalkyl optionally substituted with one or more substituents selected from the group consisting of halogen; oxo; —CN; —OH; —NH; —NH(C-Calkyl); —N(C-Calkyl): —OCO(C-Calkyl); —CO(C-Calkyl); —COH; —CO(C-Calkyl); —O(C-Calkyl); —O(C-Chaloalkyl); and a C-Caliphatic group optionally substituted with one or more substituents selected from the group consisting of halogen, oxo, —CN, —OH, —NH, —NH(C-Calkyl), —N(C-Calkyl), —OCO(C-Calkyl), —CO(C-Calkyl), —COH, —CO(C-Calkyl), —O(C-Calkyl), —O(C-Chaloalkyl), Ccycloalkyl, Ccyclo(haloalkyl), and phenyl.'}{'sup': a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a, 'sub': 2', '2', '2', '7', '3-8, 'each Q independently is selected from the group consisting of halogen; cyano; nitro; —OR; —SR; —S(O)R; —SOR; —NRR; —C(O)R; —C(O)OR; —OC(O)R; —NRC(O)R; —C(O)NRR; —NRC(O)NRR; —NRC(O)OR; —NRC(═NR)NRR, —OCONRR; —C(O)NRC(O)OR; —C(═NR)R; —C(═NOR)R; —SONRR; —NRSOR; —NRSONRR; —OP(O)(OR)OR; optionally substituted Ccarbocyclic; 4-8 membered, optionally substituted heterocyclyl; optionally substituted phenyl; and optionally substituted, 5-6 membered heteroaryl;'}{'sup': 1A', '2A', '7A', '9A', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a', 'a, 'sub': 2', '3-8', '3-8, 'each of J, J, J, and Jindependently is halogen, oxo, —CN, —OR, —NRR, —OCOR, —COR, —COR, —NRC(O)R, —C(O)NRR, —NRC(O)NRR, —NRC(O)OR, —OCONRR, Ccycloalkyl, Ccyclo(haloalkyl), or phenyl;'}{'sup': 1B', '2B', '7B', '9B', ...
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