СПОСОБ ПОЛУЧЕНИЯ АЛКИЛАМИНОАЛКИЛЕНФОСФОНОВЫХ КИСЛОТ

FIELD: chemistry. SUBSTANCE: invention relates to a method of producing alkylaminoalkylene phosphonic acids of formula U-[X-N(W)(ZPO 3 M 2 )] S , which can be used in chemical industry. The disclosed method involves reacting a compound of formula Y-X-N(W)(ZPO 3 M 2 ) with a precursor for groups U, selected from NH 3 , NH 2 R', NH(R') 2 , HOR', NaOH, Na 2 S, thiourea and Na 2 S 2 , where Y is chlorine, X is a C 2 -C 3 linear alkyl, Z is C 1 alkylene, M is H; W is ZPO 3 M 2 , U is selected from NH 2 , NHR', N(R') 2 , NH, N, OH, OR', S, SH and S-S, R' is phenyl or a C 1 -C 3 linear alkyl, s equals 1, if U is NH 2 , NHR', N(R') 2 , HS, OR or OH; s equals 2, if U is NH, S or S-S; and s equals 3, if U is N, in an aqueous medium at pH 8 or higher, at temperature from 10°C to 110°C. EFFECT: novel efficient method of producing alkylaminoalkylene phosphonic acids. 3 cl, 14 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 498 989 (13) C2 (51) МПК C07F 9/38 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2009125468/04, 11.12.2007 (24) Дата начала отсчета срока действия патента: 11.12.2007 (73) Патентообладатель(и): ДЕКВЕСТ АГ (CH) (43) Дата публикации заявки: 20.01.2011 Бюл. № 2 2 4 9 8 9 8 9 (45) Опубликовано: 20.11.2013 Бюл. № 32 (56) Список документов, цитированных в отчете о поиске: US 4330487 A1, 18.05.1982. EP 0070534 A1, 26.01.1983. US 4707306 A1, 17.11.1987. US 4260738 A, 07.04.1981. SU 960184 A1, 23.09.1982. 2 4 9 8 9 8 9 R U (86) Заявка PCT: EP 2007/063682 (11.12.2007) C 2 C 2 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 13.07.2009 (87) Публикация заявки РСТ: WO 2008/071689 (19.06.2008) Адрес для переписки: 197101, Санкт-Петербург, а/я 128, "АРСПАТЕНТ" (54) СПОСОБ ПОЛУЧЕНИЯ АЛКИЛАМИНОАЛКИЛЕНФОСФОНОВЫХ КИСЛОТ собой C1 алкилен, M представляет собой H; W представляет собой ZPO3M2, U выбран из NH2, NHR', N(R')2, NH, N, OH, OR, S, SH и S-S, R' представляет собой ...

СПОСОБ ПОЛУЧЕНИЯ АМИНОАЛКИЛЕНФОСФОНОВЫХ КИСЛОТ

... 1. Способ получения аминоалкиленфосфоновых кислот, имеющих формулугде X выбран из С-Слинейных, разветвленных, циклических или ароматических углеводородных радикалов, необязательно замещенных одной или более С-Слинейными, разветвленными, циклическими или ароматическими группами, которые (радикалы и/или группы) могут быть замещены группировками ОН, СООН, COOG, F, Br, Cl, I, OG, SOH, SOG и/или SG; ZPOM; [V-N(K)]-K; [V-N(Y)]-V или [V-O]-V; где V выбран из Слинейного, разветвленного, циклического или ароматического углеводородного радикала, необязательно замещенного одной или более Слинейными, разветвленными, циклическими или ароматическими группами, которые (радикалы и/или группы) могут быть замещены группировками ОН, СООН, COOR', F/Br/Cl/I, OR', SOH, SOR' и/или SR', где R' представляет собой Слинейный, разветвленный, циклический или ароматический углеводородный радикал, где G выбран из С-Слинейных, разветвленных, циклических или ароматических углеводородных радикалов, необязательно замещенных ...

СПОСОБ ПОЛУЧЕНИЯ АЛКИЛАМИНОАЛКИЛЕНФОСФОНОВЫХ КИСЛОТ

... 1. Способ получения алкиламиноалкиленфосфоновых кислот, имеющих формулу ! U-[X-N(W)(ZPO3M2)]s, ! посредством взаимодействия соединения фосфоновой кислоты, имеющей формулу ! Y-X-N(W)(ZPO3M2), ! с предшественником группировки: U, ! где структурные элементы имеют следующие значения: ! Y выбран из заместителей, сопряженные кислоты которых имеют значение pKa, равное или меньшее, чем 4,0; ! X выбран из C2-C50 линейных, разветвленных, циклических или ароматических углеводородных цепей, которые могут быть замещены C1-C12 линейной, разветвленной, циклической или ароматической группой, причем эта цепь и/или группа может быть замещена OH, COOH, F, OR', R2O[A-O]x-, где R2 представляет собой C1-C50 линейную, разветвленную, циклическую или ароматическую углеводородную цепь, и SR' группировками, где R' представляет собой C1-C50 линейную, разветвленную, циклическую или ароматическую углеводородную цепь, которая может быть замещена C1-C12 линейными, разветвленными, циклическими или ароматическими группами ...

N,N-Bis(Phosphonomethyl)-2-Amino-1-Propanolderivate zur Vermeidung der Scale-Bildung bei höhe pH

N-alkyl-(or-aralkyl-) substituted alkylene polyamine methylene phosphonic acid compounds

The invention comprises as new products compounds having the formula: wherein R is an alkyl or aralkyl group containing up to 18 carbon atoms; A is an alkyl or aralkyl group containing up to 18 carbon atoms, or -CH2.PO(OM)2; alkylene is -CH2CH2-, -CH(CH3)CH2- or -CH2.CH2 CH2-; n is 0, 1, 2, 3 or 4; and M is hydrogen, alkali metal, ammonium or alkyl-ammonium. The compounds may be obtained by dissolving a N-alkyl- (or -aralkyl-) substituted alkyleine polyamine in water containing sufficient caustic alkali to give a pH of from 10-11, heating the solution to a temperature of about 80-100 DEG C. and adding chloromethyl phosphonic acid disodium salt in an amount sufficient to substitute all the amino hydrogens present on the amine. The solution is then refluxed for about 10 hours or more. If the substituted alkylene polyamine is insoluble in water the reaction is carried out in absolute alcohol by dissolving the substituted alkylene polyamine in 5-10 times its volume of ...

AMPHOLYTE MIXTURES

... 1435744 Ampholytic mixtures of organophosphorus compounds N GRUBHOFER 30 April 1973 [23 June 1972] 20478/73 Addition to 1402751 Heading C2P The invention comprises an ampholytic material which is a mixture of ampholytes which contain at least 4 primary, secondary, tertiary or quaternary amino groups and at least one phosphonic acid group or a mixture of phosphonic acid and sulphonic acid groups optionally also together with carboxylic acid groups, the ratio of basic to acidic groups being different in different ampholytes. The material is prepared by reacting an aqueous polyamine solution with an aqueous solution containing a phosphonic acid or salt thereof and optionally a sulphonic acid or salt thereof and optionally reacting the product with a carboxylic acid. The polyamine used may first be alkylated. The reaction may be carried out in the presence of a catalyst or antioxidant and the products may be recovered by treatment with a cation exchange resin.

PHYSIOLOGICALLY TOLERABLE METAL COMPLEX SALTS FOR USE IN NMR DIAGNOSIS

Process for purifying aminomethylenephosphonic acids.

High purity ethylenediaminetetra (methylenephosphonic acid) and

Phosphorus functional antimicrobal coatings for metal surfaces

PROCESSES FOR PURIFYING AMINOMETHYLENE PHOSPHONIC ACIDS

Process for purifying aminomethylenephosphonic acids.

PROCESSES FOR PURIFYING AMINOMETHYLENE PHOSPHONIC ACIDS

Phosphorus functional antimicrobal coatings for metal surfaces

Phosphorus functional antimicrobal coatings for metal surfaces

POLYAMINOMETHYLENPHOSPHONAT DERIVATIVES

DIAGNOSTIC MEANS

MOUTH AND DENTAL CARE MEANS

TRIAZINDERIVATSALZE WITH OXASÄUREN OF THE PHOSPHORUS

PROCEDURE FOR THE PRODUCTION OF GLYPHOSAT AND GLYPHOSATDERIVATEN.

PHOSPHONATE.

DERIVATIVES AND AMMONIA OR DI- OR POLYAMINES

SALTS OF TRIAZINE DERIVATIVES WITH OXYGENATED ACIDS OF PHOSPHOROUS AND THEIR USE IN SELF-EXTINGUISHING POLYMERIC COMPOSITIONS

Method for the manufacture of aminoalkylene phosphonic acid

Organic phosphorus compounds and compositions embodying them

METHOD OF TREATING WATER CONTAINING FERTILISERS

IMINO ALKYLIMINO PHOSPHONATES AND METHOD FOR PREPARING AND USING SAME

METHOD FOR THE MANUFACTURE OF AMINO ALKYLENE PHOSPHONIC ACIDS

A method for the manufacture of aminoalkylene phosphonic acids broadly is disclosed. In the essence, an amine corresponding to a specific formula is reacted in aqueous medium with phosphorous acid and formaldehyde to thereby yield a medium insoluble reaction product. The insoluble product formed i.e. the aminoalkylene phosphonic acid can be separated, optionally washed, and recovered. This process yields high purity and selectivity reaction products. The excess phosphonic acid can be recycled into the processing sequence.

ORGANIC PHOSPHORUS COMPOUNDS

IMINO ALKYLIMINO PHOSPHONATES AND METHOD FOR PREPARING AND USING SAME

Imino ethylimino methyl phosphonates of the formula wherein R and M are hereinafter defined are prepared by reacting a phosphorus source (orthophosphorous acid or PCl3 and H2O), formaldehyde, and an amine of the formula R'N(CH2CH2NH2)2 wherein R' is hereinafter defined. The compounds are useful as sequestrants for metal ions, as precipitation or scale inhibitors and as corrosion inhibitors in aqueous media.

PROCESS FOR PREPARING GLYPHOSATE AND GLYPHOSATE DERIVATIVES

CHELATING AGENTS AND SCALE INHIBITORS IN DEGRADABLE DOWNHOLE TOOLS

The disclosure describes downhole tools, and methods and systems related thereto, comprising a body comprising a degradable core and a chelating agent or a chelating agent/scale inhibitor mixture integrated therein. The chelating agent and scale inhibitors help to direct and control the degradation of the degradable core.

CONDENSED POLYALKYLENEPOLYAMINE DERIVATIVES

PHOSPHORUS FUNCTIONAL ANTIMICROBIAL COATINGS FOR METAL SURFACES

The invention relates to quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, processes for preparing quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, antimicrobial coating compositions comprising quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds and method of treating a surface with said compositions to provide a durable, antimicrobial-treated surface.

MULTIFUNCTIONAL SCALE INHIBITORS

... 9882P C-1520 TITLE OF THE INVENTION MULTIFUNCTIONAL SCALE INHIBITORS Multifunctional scale inhibitor compositions, alone or together with polymeric structures, are described which are characterized by having, in addition to a phosphonomethylamino group, a sulfonic acid and/or carboxylic acid group. By incorporating several types of functional groups into a single molecule, control of scale formation and deposition under more severe conditions than normally encountered can be attained.

PROCESS OF INHIBITION OXALATE SCALE FORMATION

A process of inhibiting oxalate scale formation in aqueous systems is disclosed. A preferred class of scale inhibitors is represented by polyamino hexamethylene phosphonates. These phosphonate inhibitors can be used in levels of from 0.05 ppm to 300 ppm (of the aqueous solution) at pH in the near neutral to preferably alkaline medium.

MACROCYCLIC AMINOPHOSPHONIC ACID COMPLEXES, THEIR PREPARATION FORMULATIONS AND USE

Particle emitting radionuclides, e.g. Samarium-153, have been complexed with certain macrocyclic aminophosphonic acids wherein the nitrogen and phosphorus are interconnected by an alkylene group or substituted alkylene group. These complexes have been found useful in compositions and formulations for the therapeutic treatment of calcific tumors and the relief of bone pain in animals.

MACROCYCLIC AMINOPHOSPHONIC ACID COMPLEXES, THEIR PREPARATION FORMULATIONS AND USE

SALTS OF TRIAZINIC COMPOUNDS WITH OXYGENATED ACIDS OF PHOSPHORUS

Salts of triazinic compounds with oxygenated acids of phosphorus, of the general formula (I): (see fig. I) wherein: at least one of radicals from R to R5 is: (see fig. II) (see fig. III) being: m= an integer comprised between 2 and 8; p= an integer comprised between 2 and 6; R8=H; C1-C8 alkyl; C2-C6 alkenyl; (see fig. IV) wherein q is an integer comprised between 1 and 4 and R9 is hydrogen or C1-C4 alkyl; C6-C12 cycloalkyl or alkylcycloalkyl; radicals R', the same or different between them, are H; C1-C8 alkyl; C2-C6 alkenyl; C6-C12 cycloalkyl or alkyl-cycloalkyl, provided that radicals R6 and R7, here-inafter described are respectively different from H and OH; or the group: (see fig. V) is replaced by a heterocyclic radical bound to the alkyl chain through the nitrogen atom; or in the formula (I) at least one of groups (see fig. VI) ; (see fig. VII) ; (see fig. VIII) is replaced by a heterocyclic radical bound to the triazinic ring through the nitrogen atom; the other radicals from R to ...

N,N-BIS-PHOSPHONOMETHYL TAURINE N-OXIDE AND WATER-SOLUBLE SALTS THEREOF

This invention relates to novel organic phosphonate compounds which can be used as water treatment agents. More specifically, this invention relates to the compound N,N-bis-phosphonomethyl taurine N-oxide which may be represented by the formula: (see fig. I) and its water soluble salts, which can be employed for the control of scale and/or corrosion.

N-(2-HYDROXYETHYL)-N-BIS (METHYLENEPHOSPHONIC ACID) AND CORRESPONDING N-OXIDE THEREOF FOR HIGH PH SCALE CONTROL

... 2811H C-1573 TITLE OF THE INVENTION N-(2-hYDROXYETHYL)-N-BIS(METHYLENEPHOSPHONIC ACID) AND CORRESPONDING N-OXIDE THEREOF FOR HIGH pH SCALE CONTROL N-(2-hydroxyethyl)-N-bis(methylenephosphonic acid) and corresponding N-oxide thereof possess high calcium tolerance and have been found to give excellent inhibition of the formation, deposition and adherence of scale-forming salts, especially calcium carbonate, under severe conditions which include elevated pH, high dissolved solids content, and high saturation levels of calcium carbonate.

METAL CORROSION-INHIBITING COATING COMPOSITION COMPRISING AMINOALKYLPHOSPHONIC ACIDS

A description is given of compounds of the formula (see fig.I) in which the general symbols are as defined in claim 1, and of their zirconium, bismuth and calcium salts, and of the salts with the compounds of the formula II (see fig.II) in which the general symbols are as defined in claim 1, as corrosion inhibitors in coating compositions for protecting metallic surfaces.

Verfahren zur Herstellung von Nitrilo-tris-methylenphosphonsäure

Verfahren zur Herstellung von neuen Metallkomplexen von kationischen Farbstoffen und Verwendung derselben zum Färben von Tierhäuten

VERFAHREN ZUR HERSTELLUNG VON NITRILO-TRIS-(METHYLENPHOSPHONSAEURE).

VERFAHREN ZUR HERSTELLUNG VON AMINOMETHYLENPHOSPHONSAEUREN.

DIAGNOSTIC MEANS.

Corrosion inhibiting coating composition for metals

A coating composition comprises an organic film-forming binder and a corrosion inhibitor comprising: (A) at least one aminomethylphosphonic acid derivative of formula (I): - R1 = OH-, carboxy- or amino-substituted 4-12C alkyl; R5 = CH2P(O)(OH)2; or NR1R5 = an optionally substituted 5-7 membered ring; R2, R3 = H, 1-20C alkyl, 5-8C cycloalkyl, phenyl (optionally substituted) or benzyl; R6 = 1-18C alkyl or 7-9C phenylalkyl; and m = 0 or 1; - or (B) at least one salt derived from: (i) an aminomethylphosphonic acid derivative of formula (I'); - R1' = H, 1-25C alkyl (optionally substituted), 2-24C alkenyl, 4-15C cycloalkyl, phenyl (optionally substituted), 7-9C phenylalkyl or CR2R3P(O)(OH)(R4'); NR1'R5' = as NR1R5; R4' = H, OH or OR8; R5' = as R1' excluding substituted 2-25C alkyl; R7 = H or 1-6C alkyl; R8 = 1-6C alkyl, 4-15C cycloalkyl or phenyl (optionally substituted); and either (ii) an amine of formula (II); R14R15N-X-aR18 (II); R14, R15 = H, 1-25C alkyl (optionally interrupted by O or S ...

LOW VOLATILE AMINE SALTS OF ANIONIC PESTICIDES

HBED-AND-BISPHOSPHONATES, THEIR CONJUGATES WITH RADIOMETALLOM AND THEIR USE AS CURATIVE - DIAGNOSTIC AGENTS

LOW VOLATILE AMINE SALTS OF ANIONIC PESTICIDES

LOW VOLATILE AMINE SALTS OF ANIONIC PESTICIDES

Trimethylolpropane dendritic polymer with nuclear-end phosphonic acid end group as well as preparation method and application for same

The invention relates to a trimethylolpropane dendritic polymer with a nuclear-end phosphonic acid end group as well as a preparation method and an application for the same. The trimethylolpropane dendritic polymer with the nuclear-end phosphonic acid end group is obtained by performing Michael addition reaction on trimethylolpropane triacrylate (CH3CH2C(CH2OCOCH2=CH2)3) and alkylidene diamine (NH2CH2(CH2)nNH2, wherein n is a positive integer ranging from 1 to 5, so as to obtain a trimethylolpropane dendritic polymer with a nuclear end amine group; and then performing methylene phosphorylation on the contained amine group, wherein the chemical formula is CH3CH2C[CH2OCOCH2CH2N(CH2PO3H2)CH2(CH2)nN(CH2PO3H2)2]3, and n is a positive integer ranging from 1 to 5. The trimethylolpropane dendritic polymer with the nuclear-end phosphonic acid end group is excellent in the performance of inhibiting the scales of CaCO3, CaSO4, BaSO4 and the like, extremely high in calcium tolerance, capable of being ...

Method of preparation of acid nitrilo-sorting (methylenephosphonic)

MOUTH AND TEETH CARE MEANS FOR THE PREVENTION OF TARTAR FORMATION

PHOSPHONIC COMPOUNDS CONTAINING TERTIARY AMINE GROUPS

Sophisticated process of stabilization of the solutions of peroxidized compounds

method of making phosphonic acid aminoalquileno

ACID [...] TRIS - ([...]) AND METHOD FOR PREPARATION THEREOF

Purificaçao nao alcalina de ácidos aminofosfônicos

composto

Stabilized peroxy compositions and their use

Bridged aromatic substituted amine ligands with donor atoms

The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hydrogen, and methods for making and using these compounds.

DERIVATIVES OF ISOCYANURIC ACID AND PROCESSES FOR PREPARING THE SAME

Вridgеd аrоmаtiс substitutеd аminе ligаnds with dоnоr аtоms

Тhе prеsеnt invеntiоn prоvidеs fоr substitutеd mеtаl сhеlаting соmpоunds in whiсh аt lеаst twо оf thе сhеlаting аtоms аrе nitrоgеn whiсh аrе dirесtlу аttасhеd tо аrоmаtiс rings аnd оnе оr mоrе оf thоsе nitrоgеn аtоms hаs аttасhеd thеrеtо а substituеnt оthеr thаn hуdrоgеn, аnd mеthоds fоr mаking аnd using thеsе соmpоunds.

3-Alkoxypropylene-imino-bis(methylenephosphonic acids) and their salts, process for their preparation and their use

СПОСОБ ПРОИЗВОДСТВА АМИНОАЛКИЛЕНФОСФОНОВОЙ КИСЛОТЫ

... 1. Способ производства аминоалкиленфосфоновой кислоты, имеющей общую формулу: ! (X)a[N(W)(Y)2-a]z, ! в которой X выбран из C1-C200000 линейных, разветвленных, циклических или ароматических углеводородных радикалов, необязательно замещенных одной или более C1-C12 линейными, разветвленными, циклическими или ароматическими группами, которые (радикалы и/или группы) могут быть необязательно замещены OH, COOH, COOG, F, Br, Cl, I, OG, SO3H, SO3G и SG фрагментами; ZPO3M2; [V-N(K)]n-K; [V-N(Y)]n-V или [V-O]x-V; в которых V выбран из: C2-50 линейного, разветвленного, циклического или ароматического углеводородного радикала, необязательно замещенного одной или более C1-C12 линейными, разветвленными, циклическими или ароматическими группами, которые (радикалы и/или группы) необязательно замещены OH, COOH, COOR', F/Br/Cl/I, OR', SO3H, SO3R' или SR' фрагментами, в которых R' представляет собой C1-C12 линейный, разветвленный, циклический или ароматический углеводородный радикал; в которых G выбран из ...

METHOD OF PURIFICATION OF ETHYLENEDIAMINOTETRA(METHYLENEPHOSPHONIC ACID) OR 1,4,7,10-TETRAAZACYCLODODECANE-1,4,7,10-TETRA(METHYLENEPHOSPH- ONIC ACID)

Использование: в производстве замещенных метиленфосфоновой кислоты. Сущ- ность изобретени : способ предусматривает очистку соответствующей сырой этилендиа- минотетра(метиленфосфоновой кислоты) (Н0)2 P(0)ЈNCH2CH2N P(OXOH)2b или 1,4,7,10 -тетраазациклододекан-1,4,7,10-тетра(ме- тиленфосфоновой кислоты) путем растворени  в водном растворе гидроокиси аммони . Затем обрабатывают полученный раствор ЗМ HCI, нагрееэют реакционную смесь до 35-105°С в течение времени, достаточного дл  того, чтобы началось осаждение аминометиленфосфоновой кислоты, отфильтровывают ее кристаллы и промывают их, 3 з.п.ф-лы.

Verfahren zur Herstellung von Aldehyden durch Hydroformylierung mit einem Rhodiumkatalysator und Wiedergewinnung des Rhodiumkatalysators durch Extraktion

Described is a method of preparing aldehydes, or aldehydes and alcohols, by the hydroformylation of olefins with more than three carbon atoms, the method including a hydroformylation stage in which the olefin is hydroformylated at a pressure of 50 to 1,000 bar and a temperature of 50 to 180 DEG C by means of a rhodium catalyst dissolved in a homogeneous reaction medium and a catalyst-recovery stage in which the rhodium catalyst is extracted using an aqueous solution of a complexing agent, the alcohol and/or alkdehyde is isolated from the extracted hydroformylation products, the aqueous rhodium-containing extract is carbonylated in the presence of carbon monoxide, synthesis gas or a gas mixture containing carbon monoxide at a pressure of 50 to 1,000 bar and a temperature of 50 to 180 DEG C, the carbonylation products separated into an organic phase containing most of the rhodium and an aqueous phase containing the complexing agent and the organic phase is fed back to the hydroformylation ...

Nichtwässrige Lösungen von Alkalisalzen von Aminoalkylenphosphonsäuren und Verfahren zu deren Herstellung

Homogene flüssige Formulierung von Alkalisalzen von Aminoalkylenphosphonsäuren in einem organischen System, zumindest enthaltend:a. ein Alkalisalz einer Aminoalkylenphosphonsäure mit einem Gehalt im Bereich von 5 bis 35 Ma.-%,b. einen mehrwertigen Alkohol, ausgewählt aus 1,2-Ethylenglykol, 1,3-Propylenglykol, 1,2-Propylenglykol, Glycerin und Polyethylenglykol,c. einen Löslichkeitsvermittler, ausgewählt aus der Gruppe der Aminoalkohole, wobei der Wassergehalt der flüssigen Formulierung unter 15 Ma% liegt,wobei das Massenverhältnis von mehrwertigem Alkohol zu Löslichkeitsvermittler im Bereich von 40:1 bis 2:1 liegt.

KONTRASTMITTEL FUER NMR-AUFNAHME.

Verfahren zur Reinigung von Aminomethylenphosphonsäuren

Anwendung von Chelat-Komplexen

Method for inhibiting scale formation

A method for inhibiting the formation of scale in water having a high barium content and low pH comprises the addition of an aqueous solution of a phosphonate of formula: R = H, CH3, C2H5, M R<1>=H, CH3, CR3, C6H5, SO3H2 n = 2 - 10 m = 2 - 10 p = 0 - 10 M = alkali metal or ammonium ion. The scale inhibitors may be present in the form of a fully or partially neutralised salt and may be injected into production fluids obtained from an underground reservoir or injected into the reservoir via a wellbore as part of a squeeze technique.

DIAGNOSTIC PREPARATIONS

SCALE INHIBITION

Method for the sequestration of metal ions, and washing compositions

Alkaline washing compositions comprise an alkali cleanser (i.e an inorganic material which is alkaline in reaction and possesses cleansing properties) and an amino tri-(alkylidenephosphonic acid) of formula wherein X and Y are the same or different and are H or C1-4 alkyl, or a water-soluble salt thereof. Specified alkaline agents are alkali metal and ammonium hydroxides and carbonates, preferably NaOH in a concentration of 1-20% of an aqueous composition. The preferred amino tri-(alkylidene phosphonic acid) is amino tri-(methylphosphonic acid) in the form of its penta-sodium salt (see Division C2). The phosphonic acid component of the compositions acts as a sequestering agent for metal cations (see Division C1). The compositions are used to wash bottles and glassware and may contain an anti-corrosive agent.ALSO:Amino tri(methylphosphonic acid) is prepared by condensing diethyl phosphite with ammonia and formaldehyde in aqueous medium to give hexaethyl amino tri(methylphosphonate ...

STABILISATION OF ACTIVE OXYGEN RELEASING COMPOUNDS

... 1392284 Stabilized peroxides UNILEVER Ltd 29 March 1972 [30 March 1971] 8131/71 Heading C1A [Also in Divisions C5 and D1] Active oxygen releasing compounds are stabilized to reduce their decomposition in bleaching liquors, by admixture with a stabilizing compound of Formula I wherein M denotes H, alkali or alkaline earth metal ion, or ammonium or C 1 -C 4 alkyl substituted ammonium ion. The stabilizing compound may be present in an amount of 0À25 to 5% by weight of the active oxygen releasing compound. The latter may be organic, e.g. benzoyl peroxide, peracetic acid and its salts, or inorganic, e.g. alkali and alkaline earth metal peroxides, hydrogen peroxide, alkali metal perborates, percarbonates, persulphates and perphosphates. The compounds are preferably formulated with a surfactant as a detergent composition for cleaning textiles.

CONTRAST AGENT

CONDENSOR FOR WATER-SUSPENDED PARTICLES AND PASTES FROM HYDRAULIC BINDERS

SALTS OF TRIAZINDERIVATEN WITH OXYGENIERTER PHOSPHORIC ACID AND YOUR USE IN SELFDELETING POLYMER COMPOSITIONS

PROCEDURE FOR THE CLEANING OF AMINOMETHYLENPHOSPHONSÄUREN

REACTION PRODUCTS OF ALPHA AMINOETHYLENPHOSPHONSÄUREN AND EPOXYDVERBINDUNGEN AND YOUR USE IN COATING MEANS

Procedure for the production of Nitrilo trichloroethylene (phosphonic acidphosphonic acid phosphonic acid)

KORROSIONSINHIBIERENDE ÜBERZUGSZUSAMMENSETZUNG FÜR METALLE

WASCHMITTEL

WAESSRIGE AMINOMETHYLENPHOSPHONSAEURE SOLUTIONS, THE ORGANIC CARBOXYLATES AS STABILIZER CONTAINING.

CLEANING OF PHOSPHORUS CONNECTIONS.

DIAGNOSTISCHES MITTEL

KORROSIONSINHIBIERENDE COAT COMPOSITION FOR METALS

3-ALKOXYPROPYLENIMINO-BIS- METHYLENE PHOSPHONIC ACIDS AND THEIR SALTS

SALTS OF TRIAZINIC COMPOUNDS WITH OXYGENATED ACIDS OF PHOSPHORUS

Polyether polyamino methylene phosphonate N-oxides for high pH scale control

PROCESS FOR PURIFYING AMINOMETHYLENEPHOSPHONIC ACIDS

Method for the manufacture of aminopolyalkylene phosphonic acids

A method for the manufacture of aminopolyalkylene phosphonic acid of a specific general formula is described. In particular, a mixture of specifically defined ranges of reactants to wit: phosphorous acid; an amine; formaldehyde and an aminopolyalkylene phosphonic acid, having the same general formula as the compound to be manufactured, are reacted to thus yield a product of outstanding selectivity and purity with substantially reduced levels of non-desirable by-products.

QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION

Provided are compounds that can inhibit pathogenic, bacterial metabolite production and conjugates of the same. Also provided are pharmaceutical compositions comprising the same and methods of using the same. 5. The compound of claim 4 , wherein Ris Calkyl substituted with —O-(acylated sugar) and is optionally further substituted with oxo.6. The compound of or claim 4 , wherein Ris methyl.7. The compound of any one of claim 4 , claim 4 , and claim 4 , wherein Ris Calkyl.8. The compound of any one of - claim 4 , wherein Ris propargyl.9. The compound of claim 4 , wherein{'sup': '1', 'sub': '2-6', 'Ris Calkyl substituted with —O-(acylated sugar) and is optionally further substituted with oxo;'}{'sup': '2', 'Ris methyl;'}{'sup': '3', 'sub': '1-6', 'Ris Calkyl; and'}{'sup': '4', 'Ris propargyl.'}10. The compound of claim 4 , wherein{'sup': '1', 'sub': '2-6', 'Ris Calkyl substituted with isosorbide and is optionally further substituted with oxo and/or methene;'}{'sup': '2', 'Ris methyl;'}{'sup': '3', 'sub': '1-6', 'Ris Calkyl; and'}{'sup': '4', 'Ris propargyl.'}13. The compound of claim 4 , wherein{'sup': '1', 'sub': 3-4', '1-2, 'Ris Ccycloalkyl Calkyl;'}{'sup': '2', 'sub': '2-6', 'Ris Calkyl optionally substituted with one or two hydroxyl, oxo, and —O-(acylated sugar);'}{'sup': 1', '2', 's', 's, 'sub': 2', 'n, 'or Rand R, together with the nitrogen atom to which both are attached, combine to form a 4- or 5-membered heterocyclic ring optionally substituted with ethynyl or —(CH)—ORor an acylated sugar, wherein n is 0 or 1, Ris hydrogen or an acylated sugar;'}{'sup': '3', 'sub': '1-6', 'Ris Calkyl optionally substituted with a halogen or hydroxyl; and'}{'sup': '4', 'sub': '1-6', 'Ris Calkyl or propargyl.'}14. The compound of claim 13 , wherein Ris Ccycloalkyl Calkyl.15. The compound of or claim 13 , wherein Ris Calkyl optionally substituted with one or two hydroxyl groups.16. The compound of claim 13 , wherein Rand R claim 13 , together with the nitrogen atom to which both ...

Biological buffers with wide buffering ranges

Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range, derivatives that result in polyamines that have the same pKa yields a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability.

1,3,4-OXADIAZOLES-2-THIO DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS

The present invention relates to substituted 1,3,4-oxadiazoles-2-thio derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors. 5. A compound according to selected from:3-{[4-(1-{[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]thio}ethyl)benzyl]amino}propanoic acid;(3-{[4-(1-{[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]thio}ethyl)benzyl]amino}propyl)phosphonic acid; and(3-{[4-({[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]thio}methyl)benzyl]amino}propyl)phosphonic acid.6. A pharmaceutical composition comprising as active ingredient a therapeutically effective amount of a compound according to and a pharmaceutically acceptable adjuvant claim 1 , diluent or carrier.7. A pharmaceutical composition according to wherein the compound is selected from:3-{[4-(1-{[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]thio}ethyl)benzyl]amino}propanoic acid;(3-{[4-(1-{[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]thio}ethyl)benzyl]amino}propyl)phosphonic acid; and(3-{[4-({[5-(3,4-Dimethylphenyl)-1,3,4-oxadiazol-2-yl]thio}methyl)benzyl]amino}propyl)phosphonic acid.9. A method of claim 8 , wherein the pharmaceutical composition is administered to the mammal to treat ocular diseases claim 8 , wet and dry age-related macular degeneration claim 8 , diabetic retinopathy claim 8 , retinopathy of prematurity claim 8 , retinal edema claim 8 , geographic atrophy claim 8 , glaucomatous optic neuropathy claim 8 , chorioretinopathy claim 8 , hypertensive retinopathy claim 8 , ocular ischemic syndrome claim 8 , prevention of inflammation-induced fibrosis in the back of the eye claim 8 , various ocular inflammatory diseases including uveitis claim 8 , scleritis claim 8 , keratitis claim 8 , and retinal vasculitis; or systemic vascular barrier related diseases claim 8 , various inflammatory diseases claim 8 , including acute lung injury claim 8 , its prevention claim 8 , sepsis claim 8 , tumor ...

PHOSPHORUS FUNCTIONAL ANTIMICROBIAL COATINGS FOR METAL SURFACES

The invention relates to quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, processes for preparing quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, antimicrobial coating compositions comprising quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds and method of treating a surface with said compositions to provide a durable, antimicrobial-treated surface. 1150.-. (canceled)152. The process of wherein Rand Rare methyl.153. The process of wherein R is ethyl.154. The process of wherein n is 1 or 2.155. The process of wherein m is 17.156. The process of wherein R claim 151 , Rand Rare the same and methyl.157. The process of wherein Z is chloro or triflate.158. The process of wherein X is bromo.160. The process of wherein R is the same and ethyl.161. The process of wherein Rand Rare methyl.162. The process of wherein n is 1 or 2.163. The process of wherein m is 17.164. The process of wherein Z is bromo.165. The process of wherein the alkali carbonate is potassium carbonate.167. The process of wherein R is the same and ethyl.168. The process of wherein n is 1 or 2.169. The process of wherein the polar claim 166 , aprotic solvent is selected from the group consisting of acetonitrile claim 166 , dimethylformamide and dichloromethane.171. The process of wherein R is ethyl.172. The process of wherein Rand Ris methyl.173. The process of wherein n is 1 or 2.174. The process of wherein p is 1 or 2.175. The process of wherein Z is bromo.176. The process of wherein the polar claim 170 , aprotic solvent is selected from the group consisting of acetonitrile claim 170 , dimethylformamide and dichloromethane.178. The coating composition of wherein: in formula (I) claim 177 , Rand Rare methyl claim 177 , in is 17 claim 177 , n is 1 or 2 and X is bromo; and in formulas (XIV) and (XXVIII) claim 177 , R is the same and hydrogen claim 177 , Rand Rare methyl claim 177 , in is 17 ...

Biological Buffers with Wide Buffering Ranges

Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range, derivatives that result in polyamines that have the same pKa yields a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability. 2. The biological buffer and its salts of wherein A═D═—CH3 and m=1.3. The biological buffer and its salts of wherein A═D═—CH2OH and m=1.4. The biological buffer and its salts of wherein A═D—CH2O(CH2CH2CH2N)H and n=m=1.5. The biological buffer and its salts of wherein A═—CH2CH3 claim 1 , D═—CH2O(CH2CH2CH2N)H and n=m=1.6. The biological buffer and its salts of wherein A═—CH3 claim 1 , D═—CH2O(CH2CH2CH2N)H and n=m=1.7. The biological buffer and its salts of wherein A is —CH3 and D is —CH2CH3.9. The quaternary ammonium compound and its salts of wherein A═D═—CH3 claim 8 , E═—CH2OH claim 8 , R═R′═—CH3 and G═—H.10. The quaternary ammonium compound and its salts of wherein A═D═E═—CH2OH claim 8 , R═R′═—CH3 and G═—H.11. The quaternary ammonium compound and its salts of wherein A═D═—CH3 claim 8 , E═—CH2OH claim 8 , R═R′═—CH3 and G═—CH2CH3.12. The quaternary ammonium compound and its salts of wherein A═D═E═—CH2OH claim 8 , R═R′=—CH3 and G═—CH2CH3. This is a continuation of U.S. application Ser. No. 15/649,869 filed Jul. 14, 2017 and other previous parent applications claimed in the Application Data Sheet. U.S. application Ser. No. 15/649,869 is hereby incorporated by reference in its entirety.The present invention relates generally to the field of amines and more particularly to a classes of amines used as buffers in biological systems.Amines are very useful compounds in the buffering of biological systems. Each class of amine has various limitations which require choosing an amine ...

NOVEL DIAMINE COMPOUND AND METAL COMPLEXES, AND METHOD FOR PRODUCING OPTICALLY ACTIVE COMPOUNDS

The present invention relates to a novel diamine compound represented by the general formula (1), a ruthenium-diamine complex, an iridium-diamine complex, and a rhodium-diamine complex having the diamine compound as a ligand. Furthermore, the present invention relates to methods for selectively producing optically active compounds by using any of these complexes as a catalyst. 3. A method for producing an optically active amine or an optically active compound , comprising:{'claim-ref': {'@idref': 'CLM-00002', 'claim 2'}, 'reducing an imino group of an imine compound or an unsaturated bond of a heterocyclic compound in the presence of the complex according to and a hydrogen donor.'}4. The production method according to claim 3 , wherein the hydrogen donor is hydrogen.5. The production method according to claim 3 , wherein the hydrogen donor is selected from formic acid claim 3 , alkali metal formates claim 3 , and alcohols having a hydrogen atom on a carbon atom at an α-position of a carbon atom substituted with a hydroxyl group.6. A catalyst for asymmetric reduction claim 2 , comprising the complex according to .7. A method for asymmetric reduction of an imine compound or a heterocyclic compound comprising: reducing an imino group of the imine compound or an unsaturated bond of the heterocyclic compound in the presence of a catalyst comprising the complex according to and a hydrogen doner. The present invention relates to a novel diamine compound, a ruthenium-diamine complex, an iridium-diamine complex, and a rhodium-diamine complex having the diamine compound as a ligand, and methods for selectively producing optically active compounds important as precursors for synthesis of pharmaceuticals and functional materials by using any of these complexes as a catalyst.In the field of production of optically active amines, many asymmetric reactions including asymmetric reduction have been developed, and many asymmetric reactions using asymmetric metal complexes having ...

N-PHOSPHONOMETHYLGLYCINE GUANIDINE DERIVATIVE SALTS

The present invention provides guanidine compounds and salts thereof that may be useful, for example, in the preparation of herbicidal compositions. The compounds may be used, for example, to prepare N-phosphonomethylglycine guanidine salts having improved herbicidal efficacy over glyphosate alone. 2. The compound of wherein R claim 1 , R claim 1 , Rand Rare independently hydrogen or C-Calkyl.3. The compound of wherein Ris 3 claim 1 ,6 claim 1 ,9 claim 1 ,12 claim 1 ,15 claim 1 ,18-hexaazatriacontyl or (2 claim 1 ,3-diamino)tallow and R claim 1 , R claim 1 , Rand Rare hydrogen.4. The compound of wherein Ris 3 claim 1 ,6 claim 1 ,9 claim 1 ,12 claim 1 ,15 claim 1 ,18-hexaazatriacontyl or (2 claim 1 ,3-diamino)tallow and R claim 1 , R claim 1 , Rand Rare methyl.5. The compound of wherein Ris polyethyleneimino and R claim 1 , R claim 1 , Rand Rare hydrogen.6. The compound of wherein Ris polyethyleneimino and R claim 1 , R claim 1 , R claim 1 , and Rare methyl.7. An aqueous herbicidal composition comprising the compound of and an herbicide component comprising one or more herbicides.8. The composition of wherein the herbicide component comprises glyphosate.9. The composition of wherein the herbicide component comprises one or more water-soluble herbicides selected from the group consisting of acifluorfen claim 7 , acrolein claim 7 , amitrole claim 7 , asulam claim 7 , benazolin claim 7 , bentazon claim 7 , bialaphos claim 7 , bromacil claim 7 , bromoxynil claim 7 , chloramben claim 7 , chloroacetic acid claim 7 , clopyralid claim 7 , 2 claim 7 ,4-D claim 7 , 2 claim 7 ,4-DB claim 7 , dalapon claim 7 , dicamba claim 7 , dichlorprop claim 7 , difenzoquat claim 7 , diquat claim 7 , endothall claim 7 , fenac claim 7 , fenoxaprop claim 7 , flamprop claim 7 , flumiclorac claim 7 , fluoroglycofen claim 7 , flupropanate claim 7 , fomesafen claim 7 , fosamine claim 7 , glufosinate claim 7 , imazameth claim 7 , imazamethabenz claim 7 , imazamox claim 7 , imazapic claim 7 , ...

Phosphonate functional antimicrobial coatings for metal surfaces

The invention relates to quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, processes for preparing quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, antimicrobial coating compositions comprising quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds and method of treating a surface with said compositions to provide a durable, antimicrobial-treated surface.

Low Volatile Amine Salts of Anionic Pesticides

The present invention relates to a salt comprising an anionic pesticide and a cationic polyamine of the formula (A) or (B) as described in the description. The invention further relates to an agrochemical composition comprising said salt. It also relates to a method for preparing said salt comprising combining the pesticide in its neutral form or as salt, and the polyamine in its neutral form or as salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi. It also relates to a method of controlling undesired vegetation. Finally, the invention relates to seed comprising said salt. 15-. (canceled)7. (canceled)8. An agrochemical composition comprising at least one salt according to .9. A method for preparing the salt according to comprising combiningthe pesticide in its neutral form or as salt, andthe polyamine in its neutral form or as salt.10. The method according to claim 9 , wherein the pesticide and glyphosate are combined in water.1115-. (canceled)16. A method of combating harmful insects and/or phytopathogenic fungi claim 6 , which comprises contacting plants claim 6 , seed claim 6 , soil or habitat of plants in or on which the harmful insects and/or phytopathogenic fungi are growing or may grow claim 6 , plants claim 6 , seed or soil to be protected from attack or infestation by said harmful insects and/or phytopathogenic fungi with an effective amount of an agrochemical formulation comprising the salt of .17. (canceled)18. A method of controlling undesired vegetation claim 8 , which comprises allowing a herbicidal effective amount of the agrochemical composition according to to act on plants claim 8 , their habitat or on seed of said plants.19. Seed treated with a composition comprising the salt according to .22. The agrochemical composition of claim 8 , comprising10-70 wt % of the salt;30-90 wt % water;optionally a further pesticide; andoptionally up to 10 wt % auxiliaries, wherein the amount of all ...

Biological buffers with wide buffering ranges

Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range. Derivatives that result in polyamines that have the same pKa yield a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability.

Trimethylolpropane core, phosphonic acid terminated dendrimer and its preparation method

A trimethylolpropane core, phosphonic acid terminated dendrimer and its preparation method are provided, And a preparation method thereof comprises steps of processing Michael addition reaction on trimethylolpropane triacrylate (CHCHC(CHOCOCH═CH)) and alkylidene diamine (NHCH(CH)NH), wherein n is an integer from 1 to 5, so as to obtain trimethylolpropane core, amino group terminated dendrimer, and modifying the amino group by methylene phosphonic acid to obtain the trimethylolpropane core, phosphonic acid terminated dendrimer having a chemical formula of CHCHC[CHOCOCHCHN(CHPOH)CH(CH)N(CHPOH)], wherein n is an integer from 1 to 5. The trimethylolpropane core, phosphonic acid terminated dendrimer has high calcium tolerance, and excellent inhibiting efficiency of calcium carbonate, calcium sulfate and barium sulfate, which is applied in inhibiting the formation and deposition in industrial water systems of circulating cooling water, oilfield flooding and reverse osmosis, and particularly suitable for water treatment with high calcium tolerance. 3. The preparation method claim 2 , as recited in claim 2 , wherein in the Michael reaction of the step (1) claim 2 , a molar ratio of the trimethylolpropane triacrylate to the alkylenediamine is 1: (4˜6).4. The preparation method claim 2 , as recited in claim 2 , wherein in the methane phosphorylation of the step (2) claim 2 , a molar ratio of the intermediate trimethylolpropane core claim 2 , amino terminated dendrimer claim 2 , the phosphorous acid claim 2 , the formaldehyde and the hydrochloric acid is 1:(9.0˜9.2):(11.0˜12.0):(11.0˜12.0).5. A method of inhibiting the deposition of scale in water treatment including calcium carbonate claim 1 , calcium sulfate and barium sulfate claim 1 , comprising introducing into the water treatment an effective scale inhibiting amount of the trimethylolpropane core claim 1 , phosphonic acid terminated dendrimer having the formula as recited in claim 1 , wherein the trimethylolpropane core ...

Biological Buffers with Wide Buffering Ranges

Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range, derivatives that result in polyamines that have the same pKa yields a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability.

Biological Buffers with Wide Buffering Ranges

Amines and amine derivatives that improve the buffering range, and/or reduce the chelation and other negative interactions of the buffer and the system to be buffered. The reaction of amines or polyamines with various molecules to form polyamines with differing pKa's will extend the buffering range, derivatives that result in polyamines that have the same pKa yields a greater buffering capacity. Derivatives that result in zwitterionic buffers improve yield by allowing a greater range of stability. 2. The biological buffer and its salts of wherein A=D=—CH3 and m=1.3. The biological buffer and its salts of wherein A=D=—CH2OH and m=1.4. The biological buffer and its salts of wherein A=D-CH2O(CH2CH2CH2N)H and n=m=1.5. The biological buffer and its salts of wherein A=—CH2CH3 claim 1 , D=—CH2O(CH2CH2CH2N)H and n=m=1.6. The biological buffer and its salts of wherein A=—CH3 claim 1 , D=—CH2O(CH2CH2CH2N)H and n=m=1.7. The biological buffer and its salts of wherein A is —CH3 and D is —CH2CH3.9. The quaternary ammonium compound and its salts of wherein A=D=—CH3 claim 8 , E=—CH2OH claim 8 , R=R′=—CH3 and G=—H.10. The quaternary ammonium compound and its salts of wherein A=D=E=—CH2OH claim 8 , R=R′=—CH3 and G=—H.11. The quaternary ammonium compound and its salts of wherein A=D=—CH3 claim 8 , E=—CH2OH claim 8 , R=R′=—CH3 and G=—CH2CH3.12. The quaternary ammonium compound and its salts of wherein A=D=E=—CH2OH claim 8 , R=R′=—CH3 and G=—CH2CH3.14. The surfactant of wherein A is —H and D is —CH3.15. The surfactant of wherein A is —CH3 and D is chosen from —CH3 claim 13 , —CH2CH3 claim 13 , —CH2CH2CH3 claim 13 , —CH2OH.16. The surfactant of wherein A is —CH3 and D is chosen from —CH2CH2CH3 claim 13 , —CH2OH.17. The surfactant of wherein A is —CH3 and D is —CH2OH. This is a continuation of application Ser. No. 15/255,654 filed Sep. 2, 2016 and other previous parent applications claimed in the Application Data Sheet. application Ser. No. 15/255,654 is hereby incorporated by reference ...

Thinners for aqueous suspensions of mineral particles and hydraulic binder pastes

Use of compounds comprising at least one phosphonic amino-alkylene grouping and at least one polyoxyalkylated chain and the salts thereof, as thinning agents for aqueous suspensions of mineral particles and hydraulic binder pastes. The invention also concerns novel compounds including at least one phosphonic amino-alkylene grouping and at least one polyoxyalkylated chain as well as the salts thereof.

Process for purifying aminoethylenephosphonic acids for pharmaceutical use

내용 없음. No content.

로듐 촉매를 사용한 히드로포르밀화에 의한 알데히드의제조 방법 및 추출에 의한 로듐 촉매의 회수 방법

본 발명은 50 내지 1,000 bar의 압력 및 50 내지 180 ℃의 온도에서 균질한 반응 매질에 용해되어 있는 로듐 촉매를 사용하여 올레핀을 히드로포르밀화하는 히드로포르밀화 단계, 및 킬레이트화제 수용액을 사용한 로듐 촉매의 추출, 추출된 히드로포르밀화 생성물 스트림으로부터 알콜 및(또는) 알데히드의 분리, 50 내지 1,000 bar의 압력 및 50 내지 180 ℃의 온도에서 일산화 탄소, 합성 가스, 또는 일산화 탄소를 함유하는 가스 혼합물의 존재 하에 수성 로듐-함유 추출물의 예비카르보닐화, 로듐의 주요 부분을 함유하는 유기상 및 킬레이트화제를 함유하는 수상으로 예비카르보닐화 단계의 유출물의 분리, 유기상의 히드로포르밀화 단계로의 재순환으로 구성되는 촉매 회수 단계를 포함하는, 3 개 초과의 탄소 원자를 함유하는 올레핀의 히드로포르밀화에 의한 알데히드 또는 알데히드 및 알콜의 제조 방법에 있어서, 로듐을 킬레이트화할 수 있는 술폰산기가 없는, 수용성, 중합체 수용액을 사용하여 로듐 촉매를 히드로포르밀화 단계의 유출물로부터 추출하는 것을 특징으로 하는 방법을 제공한다.

Phosphonate ester official for metal surface can antimicrobial coating

本发明涉及包含单‑、二‑、三‑或四‑膦酸酯季铵化合物的抗微生物组合物，和涂覆有该组合物的表面，该组合物对多种革兰氏阳性和革兰氏阴性菌，包括但不限于葡萄球菌(Staphylococcus)、假单胞菌(Pseudomonas)、克雷伯氏菌(Klebsiella)、沙门氏菌(Salmonella)和利斯特氏菌(Listeria)、节杆菌(Arthrobacter)和埃希氏菌(Escherichia)，表现出抗微生物活性。

Method of increasing hydrocarbon production from subterranean formations

A method of treating a carbonate-containing subterranean formation to increase the production of hydrocarbons therefrom. The formation is contacted with an aqueous solution of one or more of certain anionic aminophosphonate compounds whereby the composition is caused to be absorbed onto the solid surfaces present in the subterranean limestone-containing formation and substantially reduces the tendency of such surfaces from becoming water or hydrocarbon wet.

Patent JPH0377463B2

Physiologically tolerable metal complex salts for use in nmr diagnosis

Method of obtaining monoethanolamine salts of phosphonic acids

FIELD: chemistry. SUBSTANCE: claimed invention relates to method of obtaining salts of phosphonic acids with improved solubility in highly mineralised waters and water-organic solvents and can be applied in oil and gas industry, heat and power engineering, household chemicals and cleaning, construction, agriculture, food industry. Claimed method includes interaction of phosphonic acid or acidic salt of phosphonic acid with base in water solution, and as base used is monoethanolamine with the following mole ratio of reagents: phosphonic acid or acidic salt of phosphonic acid: monoethanolamine from 1:2 to 1:n, where n is basicity of phosphonic acid, and phosphonic acids are selected from nitrylotrimethylphosphonic acid with n equal 6, diethylenetriaminpentamethylphosphonic acid with n equal 10, 1-hydroxyethane-1,1-diphosphonic acid with n equal 4 and 2-phosphonobutane-1,2,4-carboxylic acid with n equal 5. EFFECT: claimed is novel efficient method of obtaining salts of phosphonic acids with improved solubility. 2 cl, 8 ex, 3 tbl РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (51) МПК C07F 9/38 (11) (13) 2 529 194 C2 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2012153645/04, 11.12.2012 (24) Дата начала отсчета срока действия патента: 11.12.2012 (72) Автор(ы): Петров Сергей Юрьевич (RU) (73) Патентообладатель(и): Петров Сергей Юрьевич (RU) (43) Дата публикации заявки: 20.06.2014 Бюл. № 17 R U Приоритет(ы): (22) Дата подачи заявки: 11.12.2012 (45) Опубликовано: 27.09.2014 Бюл. № 27 2 5 2 9 1 9 4 (54) СПОСОБ ПОЛУЧЕНИЯ МОНОЭТАНОЛАМИНОВЫХ СОЛЕЙ ФОСФОНОВЫХ КИСЛОТ (57) Реферат: Настоящее изобретение относится к способу мольных соотношениях реагентов: фосфоновая получения солей фосфоновых кислот с кислота или кислая соль фосфоновой кислоты: улучшенной растворимостью в моноэтаноламин от 1:2 до 1:n, где n - основность высокоминерализованных водах и воднофосфоновой кислоты, а фосфоновые кислоты органических растворителях и ...

METHOD FOR PRODUCING AMINOPOLYALKYLENE PHOSPHONIC ACIDS

1. Способ получения аминополиалкиленфосфоновой кислоты, имеющей общую формулу (I):где Х выбран из C-Cлинейных, разветвленных, циклических или ароматических углеводородных радикалов, необязательно замещенных одной или более C-Cлинейными, разветвленными, циклическими или ароматическими группами, которые (радикалы и/или группы) могут быть замещены группировками ОН, СООН, COOG, F, Br, Cl, I, OG, SOH, SOG и/или SG; ZPOM; [V-N(K)]-K; [V-N(Y)]-V или [V-O]-V; где V выбран из: Cлинейных, разветвленных, циклических или ароматических углеводородных радикалов, необязательно замещенных одной или более Cлинейными, разветвленными, циклическими или ароматическими группами, которые (радикалы и/или группы) могут быть замещены группировками ОН, СООН, COOR', F/Br/Cl/I, OR', SOH, SOR' и/или SR', где R' представляет собой Cлинейный, разветвленный, циклический или ароматический углеводородный радикал, где G выбран из C-Cлинейных, разветвленных, циклических или ароматических углеводородных радикалов, необязательно замещенных одной или более C-Cлинейными, разветвленными, циклическими или ароматическими группами, которые (радикалы и/или группы) могут быть замещены группировками ОН, СООН, COOR', F, Br, Cl, I, OR', SOH, SOR' и/или SR'; XPOM; [V-N(K)]-K; [V-N(Y)]-V или [V-O]-V; где Y представляет собой ZPOM, [V-N(K)]-K или [V-N(K)]-V; и х представляет собой целое число от 1 до 50000; z равно от 0 до 200000, где z равно или меньше числа атомов углерода в X, и а равно 0 или 1; n представляет собой целое число от 1 до 50000; z=1, когда a=0; и Х представляет собой [V-N(K)]-K, где n представляет собой целое число от 1 до 50000, или [V-N(Y)]-V, где n представляет собой целое число от 2 до 50000, когда z=0 и a=1;Z представляет собой Cалкиленовую группу;М выбран из Н, протонированного амина, аммони� РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (51) МПК C07F 9/38 (11) (13) 2011 150 205 A (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22 ...

Bridged aromatic substituted amine ligands with donor atoms

The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hydrogen, and methods for making and using these compounds.

METHOD FOR PRODUCING MONETHANOLAMINE SALTS OF PHOSPHONIC ACIDS

1. Способ получения моноэтаноламиновых солей фосфоновых кислот, включающий взаимодействие нитрилотриметилфосфоновой кислоты или кислой соли нитрилотриметилфосфоновой кислоты с моноэтаноламином при следующих мольных соотношениях реагентов:нитрилотриметилфосфоновая кислота или кислая соль нитрилотриметилфосфоновой кислоты: моноэтаноламин от 1:1 до 1:6, где 6 - основность нитрилотриметилфосфоновой кислоты.2. Способ получения моноэтаноламиновых солей фосфоновых кислот, включающий взаимодействие диэтилентриамин-пентаметилфосфоновой кислоты или кислой соли диэтилентриаминпентаметилфосфоновой кислоты с моноэтаноламином при следующих мольных соотношениях реагентов:диэтилентриаминпентаметилфосфоновая кислота или кислая соль диэтилентриаминпентаметилфосфоновой кислоты: моноэтаноламин от 1:1 до 1:10, где 10 - основность диэтилентриаминпентаметилфосфоновой кислоты.3. Способ получения моноэтаноламиновых солей фосфоновых кислот, включающий взаимодействие 1-гидроксиэтан-1,1-дифосфоновой кислоты или кислой соли 1-гидроксиэтан-1,1-дифосфоновой кислоты с моноэтаноламином при следующих мольных соотношениях реагентов:1-гидроксиэтан-1,1-дифосфоновая кислота или кислая соль 1-гидроксиэтан-1,1-дифосфоновой кислоты: моноэтаноламин от 1:1 до 1:4, где 4 - основность 1-гидроксиэтан-1,1 -дифосфоновой кислоты.4. Способ получения моноэтаноламиновых солей фосфоновых кислот, включающий взаимодействие 2-фосфонобутан-1,2,4-трикарбоновой кислоты или кислой соли 2-фосфонобутан-1,2,4-трикарбоновой кислоты с моноэтаноламином при следующих мольных соотношениях реагентов:2-фосфонобутан-1,2,4-трикарбоновая кислота или кислая соль 2-фосфонобута� РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (51) МПК C07F 9/38 (11) (13) 2012 153 645 A (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2012153645/04, 11.12.2012 (71) Заявитель(и): Петров Сергей Юрьевич (RU) Приоритет(ы): (22) Дата подачи заявки: 11.12.2012 (43) Дата публикации заявки: 20.06.2014 Бюл. № 17 (72) Автор(ы): ...

Application and preparation method of concrete superplasticizer with phosphorous acid group

本发明公开了一种具有亚磷酸基团的混凝土超塑化剂的制备方法及其应用。本发明所述的具有亚磷酸基团的混凝土超塑化剂的制备方法，由含磷单体A、聚醚大单体B进行自由基共聚反应得到，本发明所得具有亚磷酸基团的混凝土超塑化剂可有效地改善混凝土的流动性，且可以保持混凝土的良好的工作性能；所述方法简单经济有效，尤其是可以工业化生产。

Paramagnetic polyhydric metal salt of poly-(acid-alkylene-amino)-alkane

(57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。

Method for synthesis of aminopolyalkylene phosphonic acid compounds

FIELD: chemistry. SUBSTANCE: aminopolyalkylene phosphonic acid is obtained in the presence of not more than 0.4 wt % halogen of hydrogen acid with respect to phosphorous acid, wherein all N-H groups of the amine are converted to 50% or more of the corresponding alkylene phophonic acids. Reaction of phosphorous acid (a), amine (b) and formaldehyde (c) takes place in the presence of an acid catalyst (d) with pKa ≤ 3.1, which is homogeneous with respect to the reaction medium, in the ratio: (a):(b) between 0.1:1 and 1.5:1, (c):(b) between 0.2:1 and 2:1, (c):(a) between 3:1 and 0.5:1 and (b):(d) between 40:1 and 1:5, where (a) and (c) denote number of moles, (b) denotes number of moles multiplied by number of N-H groups in the amine, (d) denotes number of moles multiplied by number of free protons in one mole of catalyst. EFFECT: shorter duration of the single-step cycle, prevention of corrosion, achieving better environmental and economical factors. 20 cl, 64 ex, 35 tbl РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 402 558 (13) C2 (51) МПК C07F 9/38 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ, ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (30) Конвенционный приоритет: 17.01.2005 EP 05447002.6 (73) Патентообладатель(и): Страйтмарк Холдинг АГ (CH) (43) Дата публикации заявки: 27.02.2009 C 2 2 4 0 2 5 5 8 C 2 R U (56) Список документов, цитированных в отчете о поиске: ЛИДИН Р.А. и др. Константы неорганических веществ. Справочник. - М., 2006, 582. MAURILIO TRAMONTI ET ALL, Tetrahedron, 1990, 46, №6, 1791-1837. GB 2138424 A, 24.10.1984. US 4931189 A, 05.06.1990. JP 57075990 A, 12.05.1982. US 3257479 A, 21.06.1966. US 3459793 A, 05.08.1969. (85) Дата перевода заявки PCT на национальную фазу: 17.08.2007 (86) Заявка PCT: EP 2005/011967 (07.11.2005) (87) Публикация PCT: WO 2006/074729 (20.07.2006) Адрес для переписки: 191186, Санкт-Петербург, а/я 230, "АРСПАТЕНТ", пат.пов. С.В.Новоселовой (54) СПОСОБ ПОЛУЧЕНИЯ СОЕДИНЕНИЙ АМИНОПОЛИАЛКИЛЕНФОСФОНОВОЙ ...

Process for purifying aminomethylenephosphonic acids

Corrosion-inhibiting coating composition for metals

A description is given of compounds of the formula in which the general symbols are as defined in claim 1, and of their zirconium, bismuth and calcium salts, and of the salts with the compounds of the formula II in which the general symbols are as defined in claim 1, as corrosion inhibitors in coating compositions for protecting metallic surfaces.

Ethylene diamino-mono-beta-propionic-tri(methylene phosphonic) - acid - as complexant for polyvalent metal ions, inhibiting stony depo

Title cpds. has ie. the formula (I) R2N-(CH2)2-N(R)-(CH2)2COOH where R = -CH2PO3H2, and they are prepd. by reacting ethylenediamino-mono-beta-propionic acid or its dihydrochloride with HCHO and a P cpd., e.g. PCl3 orthophosphorous acid or ester, or glycol chlorophosphite.

PHYSIOLOGICALLY ACCEPTABLE METAL COMPLEX SALTS FOR USE IN NMR DIAGNOSIS

Patent FR2143190B1

Fluidizers for aqueous suspensions of mineral particles and hydraulic binder pastes.

Patent FR2132215A1

CURABLE AQUEOUS THERAPY FOR USE IN UNDERGROUND AREAS, PROCESS USING SAME AND CORRESPONDING COMPOSITIONS

PROCEDE POUR LE TRAITEMENT D'UNE ZONE SOUTERRAINE, LEDIT PROCEDE CONSISTANT A METTRE EN PLACE DANS CETTE ZONE UNE COMPOSITION FORMEE PAR UNE BOUILLIE AQUEUSE DURCISSABLE, LADITE BOUILLIE COMPRENANT DE L'EAU, UN CIMENT HYDRAULIQUE ET UN AGENT RETARDATEUR DE PRISE, ET A PERMETTRE A LADITE BOUILLIE DE DURCIR, CARACTERISE PAR LE FAIT QUE L'AGENT RETARDATEUR DE PRISE EST CHOISI PARMI LES COMPOSES PORTANT DES GROUPES AMINO-N-((ALKYLIDENE)ACIDE PHOSPHONIQUE) OU LEURS SELS. LA COMPOSITION ET LE PROCEDE D'UTILISATION DE LADITE COMPOSITION SONT PARTICULIEREMENT UTILISABLES POUR LE TRAITEMENT DES PUITS DE PETROLE ET DE GAZ A TEMPERATURE ELEVEE. PROCESS FOR THE TREATMENT OF AN UNDERGROUND ZONE, THIS PROCESS CONSISTING OF PLACING IN THIS ZONE A COMPOSITION FORMED BY A HARDENABLE AQUEOUS SLURRY, THE SAID BOIL CONSISTING OF WATER, A HYDRAULIC CEMENT AND A SET-TIMING AGENT, AND ALLOWING THE SAID BOIL IS TO HARDEN, CHARACTERIZED BY THE FACT THAT THE SET-TIMING AGENT IS CHOSEN FROM THE COMPOUNDS CARRYING AMINO-N - ((ALKYLIDENE) PHOSPHONIC ACID) OR THEIR SALTS. THE COMPOSITION AND THE PROCESS FOR USING THE SAID COMPOSITION ARE PARTICULARLY USED FOR TREATMENT OF OIL AND GAS WELLS AT HIGH TEMPERATURE.

Method of producing aminoalkylene phosphonic acid

FIELD: chemistry. SUBSTANCE: invention relates to a method of producing industrially used acids of formula: (X) a [N(W)(Y) 2-a ] z , where X denotes optionally substituted C 1 -C 200000 linear, branched, cyclic or aromatic hydrocarbon, ZPO 3 M 2 , [V-N(K)] n -K, [V-N(Y)] n -V or [V-O] x -V; where V denotes optionally substituted C 2-50 linear, branched, cyclic or aromatic hydrocarbon; Y = ZPO 3 M 2 , [V-N(K)] n -K or [V-N(K)] n -V; x = 1 to 50000; z = 0 to 200000 and ≤ the number of carbon atoms in X; a = 0 or 1; n = 0 to 50000; Z - C 1-6 alkylene; M = H; W = H, X and ZPO 3 M 2 ; K = ZPO 3 M 2 or H. The method includes adding P 4 O 6 to an aqueous reaction medium containing a homogeneous Bronsted acid, wherein P 4 O 6 is hydrolysed to phosphorous acid, and said aqueous medium contains an amine of formula (X) b [N(W)(H) 2-b ] z , where b = 0 or 1, and the amine is added at the same time as P 4 O 6 or after hydrolysis of P 4 O 6 ; water after hydrolysis from 0 to 40 wt %, pH during the entire hydrolysis period is kept below 5 with subsequent addition of formaldehyde and a homogenous Bronsted acid with pKa≤3.1 and a heterogeneous Bronsted acid, with the ratios: (a) phosphorous acid, (b) amine, (c) formaldehyde and (d) Bronsted acid: (a):(b) 0.05:1 to 2:1; (c):(b) 0.05:1 to 5:1; (c):(a) 5:1 to 0,25:1; and (b):(d) 40:1 to 1:5; where (a) and (c) denote the number of moles, (b) denotes the number of moles, multiplied by the number of N-H groups in the amine, (d) denotes the number of moles, multiplied by the number of available protons per mole catalyst. EFFECT: novel efficient method of producing aminoalkylene phosphonic acids is disclosed. 14 cl, 10 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (51) МПК C07F 9/38 (11) (13) 2 525 919 C2 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2010147908/04, 24.04.2009 (24) Дата начала отсчета срока действия патента: 24.04.2009 (72) Автор(ы): НОТТЕ Патрик (BE), ДЕВО Альбер (BE) ...

Amine oxidation using carbon catalyst having oxides removed from surface

An improved process is provided for the selective production of secondary amines and primary amines by bringing together under reaction conditions a tertiary amine or a secondary amine with oxygen or an oxygen-containing gas in the presence of an activated carbon catalyst, the improvement which comprises using an activated carbon catalyst wherein oxides have been removed from the surface of the carbon.

Quaternary ammonium salts as trimethylamine production inhibitors

提供了可抑制致病性细菌代谢物产生的化合物和其结合物。还提供了包含其的药物组合物和其使用方法。

N, n-bis(phosphonomethyl)-2-amino-1-propanol, derivatives and corresponding lower alkyl ethers and n-oxides thereof for high ph scale control

N,N-bis(phosphonomethyl)-2-amino-1-propanol, derivatives and corresponding lower alkyl ethers and N-oxides thereof possess high calcium tolerance and have been found to give excellent inhibition of the formation, deposition and adherence of scale-forming salts, especially calcium carbonate, under severe conditions which include elevated pH, high dissolved solids content, and high saturation levels of calcium carbonate.

Bridged aromatic substituted amine ligands with donor atoms

The present invention provides for substituted metal chelating compounds in which at least two of the chelating atoms are nitrogen which are directly attached to aromatic rings and one or more of those nitrogen atoms has attached thereto a substituent other than hydrogen, and methods for making and using these compounds.

Decarboxylase inhibitors for treating parkinson's disease

Provided are inhibitors of pathogenic, bacterial metabolite production and conjugates of the inhibitors. Also provided are pharmaceutical compositions containing the inhibitors or conjugates and methods of using the same.

N-phosphonomethylglycine guanidine derivative salts

The present invention provides N-phosphonomethylglycine guanidine salts. The N-phosphonomethylglycine guanidine salts have improved herbicidal efficacy over glyphosate alone. The present invention also provides guanidine compounds and salts thereof.

Quaternary ammonium salts as inhibitors of trimethylamine production

Provided are compounds that can inhibit pathogenic, bacterial metabolite production and conjugates of the same. Also provided are pharmaceutical compositions comprising the same and methods of using the same.

Heterocyclic iminobismethylene bisphosphonic acid derivatives

Calcium incadronate complex and preparation method thereof

本发明公开了一种英卡膦酸钙配合物及其制备方法，其化学式为Ca(Inc)(H 2 O)，其中Ca表示钙，Inc表示英卡膦酸，H 2 O表示水，晶系为三斜晶系，空间群为P‑1，晶格常数为 α＝84.6480°，β＝89.3220°，γ＝71.4520°，z＝2。本发明是以钙盐和英卡膦酸为原料，以去离子水为溶剂，用氢氧化钠(或盐酸)溶液调节pH至2‑8，于20‑200℃下静置12‑48小时，再过滤、洗涤和干燥，得到无色透明片状晶体，即为英卡膦酸钙配合物。本发明制备方法极为简单，晶体生长速度适中，应力小，均匀性好且具有非常完整的外形，在药物缓释、靶向输运及骨组织修复等领域都具有重要的潜在应用前景。

Polyalkylene polyamino polykis methylene phosphonic acids and salts thereof and methods for producing same

THIS INVENTION RELATES O POLYALKYLENE POLYAMINO POLYKIS METHYLENE POSPHONIC ACIDS AND THEIR SALTS AND TO METHODS OF PREPARING THE SAME SUBSTANTIALLY FREE OF ANALOGUES THEREOF, IN WHICH AMINE RADICALS CONTAIN UNSUB- STITUTED PRIMARY OR SECONDARY AMINE HYDROGEN, AND TO THE PROCESS FOR USING THE SAME. D R A W I N G

METHOD FOR PREPARING A DETERGENT AND BLEACH

Non-alkaline purification of aminophosphonic acids

A process for the purification of aminophosphonic acids under non-alkaline conditions is described. In particular, aminophosphonic acids are slurred in neutral or acidic water, heated to reflux, cooled and then filtered. Product purities approaching 100 % are thus obtained.

Low volatile amine salts of anionic pesticides

The present invention relates to a salt comprising an anionic pesticide and a cationic polyamine of the formula (A) or (B) as described in the description. The invention further relates to an agrochemical composition comprising said salt. It also relates to a method for preparing said salt comprising combining the pesticide in its neutral form or as salt, and the polyamine in its neutral form or as salt. In addition, the invention relates to a method of combating harmful insects and/or phytopathogenic fungi. It also relates to a method of controlling undesired vegetation. Finally, the invention relates to seed comprising said salt.

Aqueous aminomethylenephosphonic acid solutions

Aqueous solutions of aminomethylenephosphonic acid, chiefly diethylenetriaminepenta(methylenephosphonic acid), are disclosed containing a crystallization inhibitor which is an alkali-metal salt of an organic carboxylic acid and residual hydrochloric acid originating from the manufacturing process. The equivalent molar concentration ratio of carboxylic acid salt to hydrochloric acid is greater than 1, preferably from 1.5 to 3.

Method for the manufacture of aminopolyalkylene phosphonic acids.

Se describe un método para la fabricación de ácido aminopolialquilenfosfónico de una fórmula general específica; en particular, se hace reaccionar una mezcla de gamas definidas específicamente de reactivos, a saber: ácido fosforoso; una amina; formaldehído y un ácido aminopolialquilenfosfónico, que tiene la misma fórmula general que el compuesto que se va a fabricar, para dar así un producto de selectividad y pureza excelentes con niveles sustancialmente reducidos de subproductos no deseados.

Aminophosphonic & aminophosphinic acid derivatives processes for their preparation & herbicidal compositions containing them.

The invention provides 3-amino-1,2,4-triazole salts of aminophosphonic and aminophosphinic acids. The invention also provides phototoxic compositions containing these 3-amino-1,2,4-triazole salts and processes for the preparation thereof.

Metal ion control compounds based on norbornane

The bis(methylamine) of norbornane compounds which have at least one of the amine hydrogens substituted with hydroxyalkyl, methylenephosphonic, alkylenesulfonic, carboxylic acid radicals and salts of any of the acid radicals are useful as chelating, sequestering agents. The phosphonate substituted compounds are also useful as threshold agents.

Substituted diamines and processes for preparing the same

Alkanolaminealkanephosphonic acids and derivatives thereof

Bis (aminomethyl) bicyclo [2.2.1] heptane derivative and its use

METHOD FOR PRODUCING AMINOPOLYALKYLENE PHOSPHONIC ACID COMPOUNDS IN THE PRESENCE OF A HETEROGENEOUS CATALYST

ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß RU (19) (11) 2007 130 528 (13) A (51) ÌÏÊ C07F 9/38 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÇÀßÂÊÀ ÍÀ ÈÇÎÁÐÅÒÅÍÈÅ (21), (22) Çà âêà: 2007130528/04, 07.11.2005 (71) Çà âèòåëü(è): ÒÅÐÌÔÎÑ ÒÐÅÉÄÈÍà ÃÌÁÕ (CH) (30) Êîíâåíöèîííûé ïðèîðèòåò: 17.01.2005 EP 05447003.4 (43) Äàòà ïóáëèêàöèè çà âêè: 27.02.2009 Áþë. ¹ 6 (87) Ïóáëèêàöè PCT: WO 2006/074730 (20.07.2006) Àäðåñ äë ïåðåïèñêè: 191186, Ñàíêò-Ïåòåðáóðã, à/ 230, "ÀÐÑÏÀÒÅÍÒ", ïàò.ïîâ. Ñ.Â.Íîâîñåëîâîé R U (57) Ôîðìóëà èçîáðåòåíè 1. Ñïîñîá ïîëó÷åíè àìèíîàëêèëåíôîñôîíîâîé êèñëîòû â ïðèñóòñòâèè íå áîëåå ÷åì 0,4 ìàñ.% (âûðàæåííîãî ïî îòíîøåíèþ ê êîìïîíåíòó ôîñôîðèñòîé êèñëîòû, ïðèí òîìó çà 100%) ãèäðîãàëîãåíîâîé êèñëîòû, ïîñðåäñòâîì ÷åãî âñå èìåþùèåñ N-H ãðóïïû â 50% èëè áîëåå àìèííîãî èñõîäíîãî ìàòåðèàëà ïðåâðàùàþòñ â ñîîòâåòñòâóþùèå àëêèëåíôîñôîíîâûå êèñëîòû ïóòåì âçàèìîäåéñòâè : (à):ôîñôîðèñòîé êèñëîòû; (á):àìèíà; è (â):ôîðìàëüäåãèäà; ïðè ñëåäóþùåì ñîîòíîøåíèè êîìïîíåíòîâ: (à):(á)îò 0,05:1 äî 2:1; (â):(á) îò 0,05:1 äî 5:1, è (â):(à) îò 5:1 äî 0,25:1, ãäå (à) è (â) îáîçíà÷àþò êîëè÷åñòâî èñïîëüçóåìûõ ìîëåé, à (á) ïðåäñòàâë åò ñîáîé êîëè÷åñòâî ìîëåé, óìíîæåííûõ íà êîëè÷åñòâî N-H ãðóïï â àìèíå, â ïðèñóòñòâèè ãåòåðîãåííîãî ïî îòíîøåíèþ ê ðåàêöèîííîé ñðåäå êèñëîòíîãî êàòàëèçàòîðà Áðåíñòåäà, âûáðàííîãî èç ãðóïïû, ñîñòî ùåé èç: (1) êîìáèíàöèé òâåðäîãî êèñëîòíîãî îêñèäà ìåòàëëà êàê òàêîâîãî, èëè íàíåñåííîãî íà ìàòåðèàë íîñèòåë ; (2) êàòèîíîîáìåííîé ñìîëû, âûáðàííîé èç ãðóïïû âêëþ÷àþùåé ñîïîëèìåðû ñòèðîëà, ýòèëâèíèëáåíçîëà è äèâèíèëáåíçîëà, ôóíêöèîíàëèçèðîâàííûå òàêèì îáðàçîì, ÷òîáû ïðèâèòü SO3Í ôðàãìåíòû íà àðîìàòè÷åñêóþ ãðóïïó, è ïåðôòîðèðîâàííûå ñìîëû, íåñóùèå Ñòðàíèöà: 1 RU A 2 0 0 7 1 3 0 5 2 8 A (54) ÑÏÎÑÎÁ ÏÎËÓ×ÅÍÈß ÑÎÅÄÈÍÅÍÈÉ ÀÌÈÍÎÏÎËÈÀËÊÈËÅÍÔÎÑÔÎÍÎÂÎÉ ÊÈÑËÎÒÛ Â ÏÐÈÑÓÒÑÒÂÈÈ ÃÅÒÅÐÎÃÅÍÍÎÃÎ ÊÀÒÀËÈÇÀÒÎÐÀ 2 0 0 7 1 3 0 5 2 8 (86) Çà âêà PCT: EP 2005/011968 (07.11.2005) R U (85) Äàòà ïåðåâîäà çà âêè PCT íà íàöèîíàëüíóþ ôàçó: 17.08.2007 (72) Àâòîð(û): ÍÎÒÒÅ ...

PROCESS FOR THE PURIFICATION OF AMINOMETHYLENOPHOSPHONIC ACIDS

Nmr imaging with paramagnetic polyvalent metal salts of poly(acid-alkylene-amino)-alkanes

Contrast agent for nmr scanning

ABSTRACT "CONTRAST AGENT FOR NMR SCANNING" A contrast agent for investigating the gastrointestinal tract by nuclear magnetic resonance (NMR) scanning. The contrast agent comprises a complex formed between a) an amino di- or poly-phosphonate in which the phosphonate groups comprise different carbon atoms, and b) a paramagnetic metal ion, in substantially permanent association with an insoluble particulate carrier. Suitable carriers include, for example, pharmaceutically acceptable, substantially physiologically insoluble, particulate phosphate carriers.

Method for the manufacture of aminopolyalkylene phosphonic acids

A method for the manufacture of aminopolyalkylene phosphonic acid of a specific general formula is described. In particular, a mixture of specifically defined ranges of reactants to wit: phosphorous acid; an amine; formaldehyde and an aminopolyalkylene phosphonic acid, having the same general formula as the compound to be manufactured, are reacted to thus yield a product of outstanding selectivity and purity with substantially reduced levels of non-desirable by-products.

Low volatile amine salts of anionic pesticides

New metal ion control agents based on dicyclopentadiene derivatives

Metal ion control agents based on dicyclopentadiene derivatives

ABSTRACT OF THE DISCLOSURE New compounds have been prepared from dicyclo-pentadiene bis(methylamine) which have the following formula wherein substituents A, B, X and Y each are independently selected from radicals comprising hydrogen, C2 to C6 hydroxyalkyl; hydroxyethyl- and hydroxypropylsulfonic; methylenephosphonic; methylene-, ethylene- and propylene-sulfonic, C2 to C4 alkylcarboxylic acid radicals; and the alkali metal, alkaline earth metal, ammonia, and amine salts of the foregoing acids; and wherein at least one of A, B, X, and Y is other than hydrogen. These compounds are useful as ion control (chelating) agents in aqueous solutions. In a preferred embodi-ment, the compounds have threshhold (less than stochiometric amounts required) activity.

Guanidine derivative compounds

The present invention provides guanidine compounds and salts thereof that may be useful, for example, in the preparation of herbicidal compositions. The compounds may be used, for example, to prepare N-phosphonomethylglycine guanidine salts having improved herbicidal efficacy over glyphosate alone.

Method for the Manufacture of Aminoalkylene Phosphonic Acid

A method for the manufacture of amino alkylcnc phosphonic acids is disclosed. Pure P 4 O 6 is hydrolyzed in the presence of a homogeneous Brocnstcd acid catalyst whereby the pH of the reaction medium is maintained below 5 and the free water content of said reaction medium is, after the P 4 O 6 hydrolysis has been completed, from 0 to 40 %. The required amine component can be added before, during, or in one preferred execution, after the P 4 O 6 hydrolysis has been completed. Formaldehyde is then added and the reaction mixture containing the P 4 O 6 hydrolysate, the amine and the formaldehyde is reacted in presence of a Broensted acid catalyst selected from homogeneous and heterogeneous species. The amino alkylene phosphonic acid reaction product can then be recovered in a manner known per sé.

Contrast agent for nmr scanning

A contrast agent for investigating the gastrointestinal tract by nuclear magnetic resonance (NMR) scanning. The contrast agent comprises a complex formed between a) an amino di- or poly-phosphonate in which the phosphonate groups comprise different carbon atoms, and b) a paramagnetic metal ion, in substantially permanent association with an insoluble particulate carrier. Suitable carriers include, for example, pharmaceutically acceptable, substantially physiologically insoluble, particulate phosphate carriers.

Phosphorus functional antimicrobial coatings for metal surfaces

The invention relates to quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, processes for preparing quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds, antimicrobial coating compositions comprising quaternary ammonium multi-dentate mono-, bis-, tris- and tetrakis-phosphonate compounds and method of treating a surface with said compositions to provide a durable, antimicrobial-treated surface.

Use of fluidizing agents for aqueous suspensions of mineral particles and hydraulic binder pastes, as well as new compounds

Anvendelse av forbindelser omfattende minst en fosfonisk aminoalkylengruppe og minst en polyoksyalkylert kjede og saltene derav, som fluidiseringsmidler for vandige suspensjoner av mineralpartikler og hydrauliske bindemiddelpastaer. Det beskrives også nye forbindelser omfattende minst en fosfonisk aminoalkylengruppe og minst en polyoksyalkylert kjede så vel som salter derav. Use of compounds comprising at least one phosphonic aminoalkylene group and at least one polyoxyalkylated chain and the salts thereof, as fluidizing agents for aqueous suspensions of mineral particles and hydraulic binder pastes. There are also disclosed novel compounds comprising at least one phosphonic aminoalkylene group and at least one polyoxyalkylated chain as well as salts thereof.

Metal ion sequestration process

A process for preparing a macrocyclic amino phosphonic acid complex or a physiologically acceptable salt thereof

Ethoxylated n,n-bis-phosphonomethyl 2-(hydroxy) ethylamine n-oxides and water soluble salts thereof

Process for the preparation of aminomethylenephosphonic acids

Washing compositions

Color developer and processing method using the same

There is disclosed a color developer and a method for processing a silver halide color photographic material using said color developer. The color developer comprises at thiourea compound represented by the formula (I): wherein Ri, R 2 , R 3 , and R 4 each represent a hydrogen atom, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aryl group, or a substituted or unsubstituted cycloalkylene group, provided that two or more of R 1 , R 2 , R 3 , and R 4 each do not represent a hydrogen atom at the same time; at least one pair of R 1 and R 3 , and R 2 and R 4 , together may bond to form a nitrogen-containing heterocyclic ring; or at least one pair of R 1 and R 2 , and R 3 and R 4 , together may bond to form a ring.

N-bis(phosphonomethyl) amino and their use as scale inhibitors

Certain N-bis(phosphonomethyl) amino acids are novel compounds and are useful in preventing calcium carbonate scale.

HEXAMETILENE PHOSPHONATE CONCENTRATES.

SE DESCRIBEN SOLUCIONES ACUOSAS CONCENTRADAS DE ACIDO FONICO DE HEXAMETILENO QUE CONTIENEN, ADEMAS DE ALTOS NIVELES DE ACIDO FOSFONICO, P. EJ. DE UN 40% A UN 50%, UN NIVEL MINUCIOSAMENTE DEFINIDO DE UN ACIDO MINERAL NO OXIDANTE, PREFERENTEMENTE ACIDO CLORHIDRICO.

Diagnostic agent for use in in vivo NMR diagnostics, method of preparation thereof and complex salts suitable for use in the diagnostic agent

Process for the manufacture of alkylamino alkylene phosphonic acids

A process for the manufacture of alkylamino alkylene phosphonic acids is disclosed. In detail, a specific phosphonate is reacted with an agent selected to yield an alkylamino moiety substituted by a radical selected from OH, OR', NH 2 , NHR', N(R') 2 , NH, N, S, S-S and SH in aqueous alkaline medium having a pH of 8 or higher at a temperature of 0°C or higher.

Compound for bone scanning and use thereof

본 발명은 비스포스페이트 작용기 및 킬레이트화제를 포함하는 화합물을 제공한다. 비스포스페이트 작용기 부분은 골 조직에 높은 친화성을 가지며, 킬레이트화제 부분은 방사성 동위원소와 같은 금속성의 추적자에 높은 친화성을 가진다. 개시된 화합물은 골 표면에 신속하게 흡착될 수 있고 이온화 방사선을 안정하게 방출할 수 있다. 따라서 개시된 화합물은 뼈의 이상을 발견하기 위한 골 스캔 기술에 유용하다.

Nitrogen-phosphorus composite flame retardant, blended fabric, preparation method and application of blended fabric

本发明涉及纺织技术领域，具体公开了一种氮磷复合阻燃剂、混纺织物、制备方法及其应用，所述氮磷复合阻燃剂可以用于提高现有纺织品的阻燃性能，解决了现有纺织品材料大多存在不具有良好阻燃性能的问题；而本发明提供的制备方法简单，制备得到的氮磷复合阻燃剂在处理涤纶后和毛织物混纺得到毛涤混纺织物，会由于毛织物的支架作用消除涤纶融滴现象的生成。而且，得到的混纺织物既有很好的阻燃性能又能保证抗拉伸性能，减少了融滴滴落的现象，并且防止涤纶融滴的碳化，提高了高温碳含量，这不仅保证了阻燃性也解决了融滴二次伤害的问题，大大扩大了阻燃型涤纶的应用范围，具有广阔的应用前景。

Crystalline anhydrous amino tri(methylenephosphonic acid)

CRYSTALLINE ANHYDROUS AMINO TRI(METHYLENEPHOSPHONIC ACID) USEFUL AS A SEQUESTERING AGENT, A DEFLOCCULATING AGENT AND A DETERGENT BUILDER.

Nanoparticle, contrast agent for magnetic resonance imaging comprising same and zwitterionic ligand compound

Provided is a novel nanoparticle, a contrast agent for magnetic resonance imaging containing the same, and a zwitterionic ligand compound used in production of the nanoparticle. The contrast agent for MRI of the present invention can be suitably used as a contrast agent for MRI in a medical field. The nanoparticle and the zwitterionic ligand compound of the present invention are applicable to various pharmaceutical compositions and the like, including a contrast agent for MRI, and can be used widely in the fields of pharmaceuticals, biotechnology, and the like, including various diagnosis methods and examination reagents.

Ethylene diamino mono beta propionic trimethylene phosphonic - acid prepn - by reacting acrylic acid and ethylene diamine with forma

Ethylene diamino-mono beta-propionic tri(methylene phosphonic) acid (I) of formula:- is prepared by reacting acrylic acid with ethylene diamine in presence of formalin and with addn. of phosphorus trichloride dropwise. The method eliminates the need to prepare ethylene diamino mono beta-propionic acid as described in BE 782211.

N,N-bis-phosphonomethyl taurine N-oxide and water-soluble salts thereof

This invention relates to novel organic phosphonate compounds which can be used as water treatment agents. More specifically, this invention relates to the compound N,N-bis-phosphonomethyl taurine N-oxide which may be represented by the formula: <IMAGE> and its water soluble salts, which can be employed for the control of scale and/or corrosion.

Method for the manufacture of aminoalkylene phosphonic acid

本发明公开了制造氨基亚烷基膦酸的方法。在均相布朗斯台德酸催化剂的存在下，由此反应介质的pH保持低于5，将纯P 4 O 6 水解，并且在P 4 O 6 水解已经完成之后，所述反应介质的游离水含量为0至40％。需要的胺组分可以在所述P 4 O 6 水解之前添加，在所述P 4 O 6 水解过程中添加，或在一个优选的实施方式中，在所述P 4 O 6 水解已经完成之后添加。然后添加甲醛，并在布朗斯台德酸催化剂的存在下，使含有所述P 4 O 6 水解物、所述胺和所述甲醛的反应混合物进行反应，所述布朗斯台德酸催化剂选自均相和多相物质。然后以本身已知的方式回收所述氨基亚烷基膦酸反应产物。

NON-ALKALINE CLEANING OF AMINOPHOSPHONIC ACIDS

Macrocyclic aminophosphonic acid complexes, their preparation, formulations and use

Process for the manufacture of aminoalkylenephosphonic acid compounds in the presence of a heterogeneous catalyst

A beneficial method for the manufacture of amino polyalkylene phosphonic acids, under substantial absence of hydrohalogenic acid, is disclosed. The method, in essence, is based on reacting narrowly defined ratios of phosphorous acid, an amine and a formaldehyde in presence of a heterogeneous Broensted acid catalyst. The inventive method is capable of yielding economically and quality operational/capacity advantages, in particular significantly reduced one-step cycle duration under exclusion of corrosion disadvantages and also is environmentally friendly without requiring, in that respect, anything more than nominal capital expenditures.

Macrocyclic aminophosphonic acid complexes, their preparation, preparation and application

本发明公开了一种由发射粒子的放射性核素，如钐-153与某些大环氨基膦酸(其中氮原子和磷通过亚烷基或取代的亚烷基连接)在水中和在控制的pH值下进行反应制备配合物的方法。已发现这些配合物制成的组合物和制剂可用于治疗动物的钙化肿瘤和消除骨骼疼痛。

Process for the preparation of highly pure aminoalkylenephosphonic acids

Verfahren zur Reinigung einer Aminoalkylenphosphonsäure, umfassend die folgenden Schritte:a) Kontaktieren eines wässrigen Rohprodukts, enthaltend mindestens eine Aminoalkylenphosphonsäure, ausgewählt aus HEMPA, DTPMP und BHMTMP mit einem Gesamtanteil im Bereich von 1 bis 80 Ma.-%, mit einem erstem Fällungsreagenz, in einem pH-Bereich von 3 bis 10, wobei das erste Fällungsreagenz multivalente Metallkationen aus der Gruppe der Erdalkalimetallionen und/oder Schwermetallionen sind, wobei ein Präzipitat A ausfällt,b) Abtrennung des Präzipitats A, enthaltend mindestens eine Aminoalkylenphosphonsäure von dem Überstand aus (a),c) Kontaktieren des Präzipitats A mit einem zweiten Fällungsreagenz bei einem pH-Wert von kleiner 4, wobei das zweite Fällungsreagenz Schwefelsäure und/oder Oxalsäure ist und wobei ein Präzipitat B ausfällt, undd) Abtrennung des Überstandes aus (c), enthaltend mindestens eine Aminoalkylenphosphonsäure vom Präzipitat B,e) Abtrennung von Wasser aus dem Überstand erhalten in (d),so dass eine konzentrierte Lösung oder ein Kristallisat, enthaltend HEMPA, DTPMP oder BHMTMP mit einem Reinheitsgrad von mehr als 95 Ma.-%, entsteht. A process for purifying an aminoalkylenephosphonic acid, comprising the steps of: a) contacting an aqueous crude product containing at least one aminoalkylenephosphonic acid selected from HEMPA, DTPMP and BHMTMP in a total proportion in the range of 1 to 80% by mass, with a first precipitating reagent, in a pH range of 3 to 10, wherein the first precipitation reagent are multivalent metal cations from the group of alkaline earth metal ions and / or heavy metal ions, precipitate A precipitates, b) separation of precipitate A containing at least one aminoalkylene phosphonic acid from the supernatant of (a) c) contacting the precipitate A with a second precipitating reagent at a pH of less than 4, the second precipitating reagent being sulfuric acid and / or oxalic acid and precipitating a precipitate B, andd) separating the ...

Nu-alkyl substituted alkylene polyamine methylene phosphonic acids

Process for the selective production of secondary and primary amines