ПРИМЕНЕНИЕ ПО МЕНЬШЕЙ МЕРЕ ОДНОГО БИНАРНОГО СОЕДИНЕНИЯ ЭЛЕМЕНТА ГРУППЫ 15, 13/15 ПОЛУПРОВОДНИКОВОГО СЛОЯ И БИНАРНЫХ СОЕДИНЕНИЙ ЭЛЕМЕНТА ГРУППЫ 15

Изобретение относится к применению по меньшей мере одного бинарного соединения элемента группы 15 в качестве эдукта в методике осаждения из паровой фазы. Бинарное соединение элемента группы 15 описывается общей формулойв которой Rи Rнезависимо друг от друга выбраны из группы, включающей алкильный радикал (С-С), R=R=Н и Е и Е' независимо друг от друга выбраны из группы, включающей N, Р, As и Bi, в которой Е=Е' или Е ≠ Е', и в котором гидразин и его производные исключены из указанного применения, и/или бинарное соединение элемента группы 15 описывается общей формулойв которой R, Rи Rнезависимо друг от друга выбраны из группы, включающей Н, алкильный радикал (C-С), и Е и Е' независимо друг от друга выбраны из группы, включающей N, Р, As и Bi, в которой Е=Е' или Е ≠ Е'. Бинарные соединения элемента группы 15 обеспечивают реализацию воспроизводимого получения и/или осаждения многокомпонентных, однородных и сверхчистых полупроводников определенной комбинации при относительно низких используемых ...

СПОСОБ ОЛИГОМЕРИЗАЦИИ ЭТИЛЕНА В СРЕДЕ ОРГАНИЧЕСКОГО РАСТВОРИТЕЛЯ В ПРИСУТСТВИИ ХРОМОВОГО КАТАЛИЗАТОРА И АЛЮМИНИЙОРГАНИЧЕСКОГО АКТИВАТОРА

Изобретение относится к области промышленного получения гексена-1 и октена-1 олигомеризацией этилена и может быть использовано в нефтехимической промышленности и в органическом синтезе. Предложен способ получения гексена-1 и октена-1. Олигомеризацию этилена осуществляют при умеренно повышенных температурах (30-60°С) и давлении (2-5 мПа) в присутствии катализатора, полученного на основе смесей соли хрома(III) и конформационно жестких хелатных дифосфиновых лигандов, активированных матилалюмоксаном, при этом в качестве лигандов используются соединения нового структурного типа на основе 5,6-дигидродибензо[с,е][1,2]азафосфинина общей формулы: где R1 - алкильный или арильный заместитель, a R2 – орто-замещенный фенильный фрагмент. Продукты реакции выделают ректификацией под атмосферным давлением. Предпочтительно в качестве лиганда использовать дифосфиновые лиганды, содержащие трет-бутильный заместитель или орто-метоксифенильный заместитель R1 и орто-метоксифенильные заместители R2. Технический ...

СПОСОБ ПОЛУЧЕНИЯ СОЕДИНЕНИЯ, СОЕДИНЕНИЯ, КОМПЛЕКСНЫЙ МЕТАЛЛООРГАНИЧЕСКИЙ КАТАЛИЗАТОР

... 1. Способ получения соединения формулы (I)в которой R1 и R2 могут быть одинаковыми или различными и по отдельности представляют собой замещенную или незамещенную группу, выбранную из алкильной, циклоалкильной, арильной, алкилокси-, циклоалкилокси-, арилокси, алкиламино-, циклоалкиламино, ариламино, металлоценильной группы;R3, R4, R5, R6 могут быть одинаковыми или различными и по отдельности представляют собой атом водорода либо замещенную или незамещенную группу, выбранную из алкильной, циклоалкильной, арильной, алкилокси-, циклоалкилокси-, арилокси-, алкиламино-, циклоалкиламино-, ариламиногруппы;Е представляет собой замещенную или незамещенную группу, выбранную из PR7R8, P(BH)R7R8, -CH-PR7R8, -CH-P(BH)R7R8, -BR9R10, -CR11R12OH, -COR11, -SiR11R12R13; -SiR11R12-CH-PR7R8;где R7 и R8 могут быть одинаковыми или различными и по отдельности представляют собой водород, замещенную или незамещенную группу, выбранную из алкильной, циклоалкильной, арильной, алкилокси-, циклоалкилокси-, арилокси, ...

Additionspolymerisationskatalysator mit eingeschränkter Geometrie, Verfahren zur Herstellung davon, Vorläufer dafür, Verfahren zur Verwendung und daraus hergestellte Polymere

METALLORGANISCHE ADDUKTVERBINDUNGEN.

A process for the manufacture of organic addition compounds containing heavy metals

Complex double compounds containing metals are prepared by combining non-noble heavy metal compounds derived from amines, acid amides including urea, nitriles, aminoalcohols or oximes which in aqueous or alcoholic solution do not have an acid reaction to phenol phthalein, with completely alkylated and/or arylated compounds of nitrogen, phosphorus or sulphur not substituted in the alkyl or aryl groups, or with alkyl and/or aryl phosphites. The metal compounds may be prepared in situ, e.g. by reacting the oxides or hydroxides of the metals with the nitrogen-containing organic compounds. The products are useful as additions to hydrocarbon mixtures; when added to gasolines they improve their anti-knock properties, whilst in the case of lubricants they render them suitable as extreme pressure lubricants or act as anti-oxidants. Examples of organic metallic compounds are cupro-urea, silver acetamide, cupro-aniline, nickel formamide and formanilide, cobalti - formanilide, cupro - acetamide and ...

Process for the preparation of aldehydes and/or alcohols

An aldehyde and/or an alcohol is obtained by reacting an olefin with carbon monoxide and hydrogen in the presence of a complex containing in the molecule a transition metal having an atomic number from 23 to 32, 40 to 51, or 57 to 84 and at least one molecule of a biphyllic ligand containing trivalent phosphorus, arsenic or antimony as a catalyst. The preferred transition metals are iron, nickel, ruthenium, rhodium, palladium, osmium, iridium, platinum and, particularly, cobalt. A preferred class of catalysts are those having the formula [(Rz1A)x-L-Ry]pM(CO)n in which (Rz1A)x-L-Ry represents the biphyllic ligand, M is a transition element as defined above, L is phosphorus, arsenic or antimony, R and R1 are alkyl, aryl, aralkyl or alkaryl groups, A is oxygen, nitrogen or sulphur, x is 0-3, y is 3-x, p varies from 1 to the co-ordination member of the transition metal, n + p is equal to the co-ordination number and z is 1 where A is oxygen or sulphur or 2 when A is nitrogen. The olefines used ...

Anti-bacterial compounds

A process for manufacturing organic addition compounds containing metals

Complex double compounds containing metals, which are useful as additions to hydrocarbons, e.g. gasoline, lubricating oils, tar oils, and brown coal products, as anti-detonants, anti-oxidants, or improvers, comprise the reaction products of an alkali metal derivative of an aromatic hydrocarbon with a complex compound formed of an inorganic or organic non-noble heavy metal compound and a completely alkylated and/or arylated compound of nitrogen, phosphorus or sulphur not substituted in the alkyl or aryl group. The radicle attached to the metal in the latter complex compounds is thereby replaced by an aromatic hydrocarbon radicle. Examples are given of the preparation of cuprophenyl-triethyl phosphine, nickel diphenyl-triethyl phosphine, cuprophenyl-trimethylamine, and silver a -naphthyl-triethyl phosphine. In addition, the following components are referred to: pyridine, triethylamine, tripropyl phosphine, triphenyl phosphine, thioether, ethylene diethyl sulphide and dibutyl sulphide. Specifications ...

VERFAHREN ZUR HYDRIERUNG DER EXOCYCLISCHEN METHYLENGRUPPE EINES 6-DEOXY-6-DEMETHYL-6-MEHTYLENTETRACYCLINS

PROCEDURE FOR THE PRODUCTION OF PHOSPHIN BORANKOMPLEXEN

CHIRALE OF PHOSPHINIGSÄURE BORANE DERIVATIVES, YOUR PRODUCTION AND USE.

ADDITION POLYMERIZATION CATALYSTS WITH REDUCED GEOMETRY, PROCEDURE FOR THE PRODUCTION OF IT, FORERUNNERS FOR IT, PROCEDURES FOR THE USE AND FROM THIS MANUFACTURE OF POLYMERS

ADDITION POLYMERIZATION CATALYST, PROCEDURE FOR THE PRODUCTION OF IT, FORERUNNERS FOR IT AND PROCEDURES FOR THE USE

SULFONIERTE PHENYLPHOSPHANE ABSTENTION COMPLEX CONNECTIONS

SULFONIERTE PHENYLPHOSPHANE ABSTENTION COMPLEX CONNECTIONS

ANTI-ARTHRITIC COMPOSITIONS

LIGANDS FOR USE IN CATALYTIC PROCESSES

COMPLEX COMPOUNDS CONTAINING SULFONATED PHENYL PHOSPHANES

INTEGRATED PROCESS FOR PREPARATION OF DIENE COMPLEXES

Disclosed is a process for prepararing bridged Group 4 metal complexes containing a neutral dime ligand starting from the corresponding novel, metal diene containing complexes by reaction thereof with the divalent derivative of a bridged bidentate ligand compound. The novel, intermediate metal diene complexes, their formation from tetravalent metal salts and an integrated process combining both process steps are claimed.

INORGANIC LITHIUM SALT COMPLEXES AND METHOD OF PREPARING THE SAME

TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST

The invention provides a mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms, of which at least one heteroatom is sulfur and at least 2 heteroatoms are not the same.The invention also provides a multidentate mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms of which at least one is a sulfur atom. The ligand may also contain, in addition to sulfur, at least one nitrogen or phosphorous heteroatom.

ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIX PHOSPHORUS COMPOUND USING SAID PHOSPHIDE

The present invention addresses the problem of providing: a novel organic magnesium phosphide characterized by having a phosphorus-magnesium bond and a method for producing the organic magnesium phosphide; and a novel organic magnesium phosphide complex and a method for producing the organic magnesium phosphide complex. The present invention also addresses the problem of providing a novel method for producing an organic phosphorus-containing compound using the organic magnesium phosphide or the organic magnesium phosphide complex. As a solution, an organic magnesium phosphide represented by formula (1) and an organic magnesium phosphide complex represented by formula (9) are provided. Also provided is a method for producing an organic phosphorus-containing compound, characterized by reacting any one of the reagents with an electrophile. (In the formula, R1 and R2 independently represent an aliphatic group, a heteroaliphatic group, an alicyclic group or a heterocyclic group; and X represents ...

AN ADAMANTYL CATALYST SYSTEM

... ²²²A catalyst system capable of catalysing the carbonylation of an olefinally ²unsaturated compound is described. The 5 catalyst system is obtainable by ²combining: (a) a metal of Group VIB or Group VIII B or a compound thereof; and ²(b) a bidentate phosphine of general formula (I) Ad) s (CR4R5R6) T Q2-A- (K, ²D) Ar (E, Z) -B-Q1 (Ad) u (CR1R2R3) v. Ad represents an optionally substituted ²adamantyl radical bonded to the phosphorous atom via any one of its tertiary ²carbon atoms. A method of production of the catalyst is also illustrated.² ...

FERROCENE-BASED COMPOUNDS AND PALLADIUM CATALYSTS BASED THEREON FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS

The invention relates to a compound of formula (I) (see formula I) where R1, R2, R3, R4 are each independently selected from -(C1-C12)-alkyl, -(C3-C12)-cycloalkyl, -(C3-C12)-heterocycloalkyl, -(C5-C20)-aryl, -(C3-C20)-heteroaryl; at least one of the R1, R2, R3, R4 radicals is a -(C6-C20)-heteroaryl radical having at least six ring atoms; and R1, R2, R3, R4, if they are -(C1-C12)-alkyl, -(C3-C12)-cycloalkyl, -(C3-C12)-heterocycloalkyl, -(C6-C20)-aryl, -(C3-C20)-heteroaryl or -(C6-C20)-heteroaryl, may each independently be substituted by one or more substituents selected from -(C1-C12)-alkyl, -(C3-C12)-cycloalkyl, -(C3-C12)-heterocycloalkyl, -O-(C1-C12)-alkyl, -O-(C1-C12)-alkyl-(C6-C20)-aryl, -O-(C3-C12)-cycloalkyl, -S-(C1-C12)-alkyl, -S-(C3-C12)-cycloalkyl, -COO-(C1-C12)-alkyl, -COO-(C3-C12)-cycloalkyl, -CONH-(C1-C12)-alkyl, -CONH-(C3-C12)-cycloalkyl, -CO-(C1-C12)-alkyl, -CO-(C3-C12)-cycloalkyl, -N-[(C1-C12)-alkyl]2, -(C6-C20)-aryl, -(C6-C20)-aryl-(C1-C12)-alkyl, -(C6-C20)-aryl-O-(C1-C12 ...

PROCESS FOR THE ALKOXYCARBONYLATION OF ALCOHOLS

The invention relates to a process comprising the following process steps: a) introducing a first alcohol, the first alcohol having 2 to 30 carbon atoms; b) adding a phosphine ligand and a compound which comprises Pd, or adding a complex comprising Pd and a phosphine ligand; c) adding a second alcohol; d) supplying CO; e) heating the reaction mixture, the first alcohol reacting with CO and the second alcohol to form an ester; where the phosphine ligand is a compound of formula (I) where m and n are each independently 0 or 1; R1, R2, R3, R4 are each independently selected from -(C1-C12)-alkyl, -(C3-C12)- cycloalkyl, -(C3- C12)-heterocycloalkyl, -(C6-C20)-aryl, -(C3-C20)-heteroaryl; at least one of the R1, R2, R3, R4 radicals is a -(C3-C20)-heteroaryl radical; and R1, R2, R3, R4, if they are -(C1-C12)-alkyl, -(C3-C12)-cycloalkyl, -(C3-C12)- heterocycloalkyl, -(C6- C20)-aryl or -(C3-C20)-heteroaryl, may each independently be substituted by one or more substituents selected from -(C1-C12)-alkyl ...

BENZENE-BASED DIPHOSPHINE LIGANDS FOR ALKOXYCARBONYLATION

The invention relates to compounds of formula (I) (see formula I) where m and n are each independently 0 or 1; R1, R2, R3, R4 are each independently selected from -(C1-C12)-alkyl, -(C3-C12)- cycloalkyl, -(C3- C12)-heterocycloalkyl, -(C6-C20)-aryl, -(C3-C20)-heteroaryl; at least one of the R1, R2, R3, R4 radicals is a -(C3-C20)-heteroaryl radical; and R1, R2, R3, R4, if they are -(C1-C12)-alkyl, -(C3-C12)-cycloalkyl, -(C3-C12)- heterocycloalkyl, -(C6- C20)-aryl or -(C3-C20)-heteroaryl, may each independently be substituted by one or more substituents selected from -(C1-C12)-alkyl, -(C3-C12)-cycloalkyl, -(C3-C12)-heterocycloalkyl, -O-(C1-C12)- alkyl, -O-(C1-C12)- alkyl-(C6-C20)-aryl, -O-(C3-C12)-cycloalkyl, -S-(C1-C12)-alkyl, -S-(C3-C12)- cycloalkyl, -COO-(C1- C12)-alkyl, -COO-(C3-C12)-cycloalkyl, -CONH-(C1-C12)-alkyl, -CONH-(C3-C12)- cycloalkyl, -CO- (C1-C12)-alkyl, -CO-(C3-C12)-cycloalkyl, -N-[(C1-C12)-alkyl]2, -(C6-C20)-aryl, -(C6-C20)-aryl-(C1- C12)-alkyl, -(C6-C20)-aryl-O-(C1-C12)-alkyl ...

COMPLEX COMPOUNDS CONTAINING SULFONATED PHENYL PHOSPHANES

Verfahren zur Herstellung von kohlenoxydfreien Komplexen der Übergangsmetalle mit C-C-Mehrfachbindungen enthaltenden Stoffen

Verfahren zur Herstellung von Übergangsmetallkomplexen ohne Carbonyl-Liganden

Process for the preparation of an alpha-6-deoxytetracyclin

The improved process applies to the preparation of a 6-deoxytetracycline by hydrogenation of a 6-deoxy-6-demethyl-6-methylenetetracycline. The process makes possible a stereoselective hydrogenation in favour of the alpha isomer, and it is characterised in that the hydrogenation is carried out at a temperature of 20 to 100 DEG C and at a pressure of 20 to 100 atmospheres, under practically neutral or slightly acidic conditions, in the presence of a catalyst of formula Rh(OCOR)2(P[C6H5]3) in which R = hydrogen, C1 to C6 alkyl, chloromethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, phenyl, chlorophenyl, tolyl or anisyl.

USE OF CYCLOVINYL PHOSPHINE/COPPER COMPLEXES AS CATALYSTS FOR ARYLATION

CHIRAL PHOSPHINITE-BORANES, PREPARATION THEREOF AND APPLICATIONS.

PHOSPHINE OR PHOSPHITE GOLD COMPLEXES OF THIOBENZOIC ACID AND SUBSTITUTED THIOPHENOLS AND ANTI-ARTHRITIC COMPOSITIONS COMP RISING THEM

ANTI?ARTHRITIC COMPOSITIONS COMPRISING AN S?PHOSPHINE OR PHOSPHITE GOLD THIO?CYANATE AND METHODS OF PRODUCING ANTI?ARTHRITIC ACTIVITY

New quaternary onium metal complexes useful for treating cancer

La présente invention concerne des complexes métalliques d'onium quaternaire répondant à la formule : [(R)L M' Xm]2+ [M"Zn . 2M'''Yp. M'''Wq]2- (I) dans laquelle : - R est un onium quaternaire choisi parmi les phosphoniums, les ammoniums quaternaires, l'isothiouronium ou le sulfonium ; - M' représente au moins un métal ayant un degré d'oxydation de 4 ; - M" représente au moins un métal ayant un degré d'oxydation de 2 ou 3 ; - M"' représente au moins un métal ayant un degré d'oxydation de 3 ; - X, Y, Z et W identiques ou différents, sont des ions halogénures, de préférence des ions chlorures ; - m est égal à 0, ou bien est un nombre entier égal à 2 ou plusieurs fractions dont la somme est égale à 2 ; -L est égal à 2 ou 4 ; - n, p, q sont des nombres entiers égaux à 3 ou 4 ou des fractions dont la somme est 3 ou 4.

FERROCENE-BASED COMPOUNDS AND PALLADIUM CATALYSTS BASED UPON THE SAME FOR THE COMPOUNDS IN PLACE ALCOXICARBONILACIÓN ETHYLENICALLY

Compuestos de fórmula (1), donde R¹, R², R³, R⁴ son, cada uno, independientemente seleccionados entre -alquilo-C₁₋₁₂, -cicloalquilo-C₃₋₁₂, -heterocicloalquilo-C₃₋₁₂, -arilo-C₆₋₂₀, -heteroarilo-C₃₋₂₀; por lo menos uno de los radicales R¹, R², R³, R⁴ es un radical -heteroarilo-C₆₋₂₀ que tiene por lo menos seis átomos en el anillo; y R¹, R², R³, R⁴, si son -alquilo-C₁₋₁₂, -cicloalquilo-C₃₋₁₂, -heterocicloalquilo-C₃₋₁₂, -arilo-C₆₋₂₀, -heteroarilo-C₃₋₂₀ o heteroarilo-C₆₋₂₀, cada uno puede estar sustituido independientemente por uno o más sustituyentes seleccionados entre -alquilo-C₁₋₁₂, -cicloalquilo-C₃₋₁₂, -heterocicloalquilo-C₃₋₁₂, -O-alquilo-C₁₋₁₂, -O-alquil-C₁₋₁₂-arilo-C₆₋₂₀, -O-cicloalquilo-C₃₋₁₂, -S-alquilo-C₁₋₁₂, -S-cicloalquilo-C₃₋₁₂, -COO-alquilo-C₁₋₁₂, -COO-cicloalquilo-C₃₋₁₂, -CONH-alquilo-C₁₋₁₂, -CONH-cicloalquilo-C₃₋₁₂, -CO-alquilo-C₁₋₁₂, -CO-cicloalquilo-C₃₋₁₂, -N-[-alquilo-C₁₋₁₂]₂, -arilo-C₆₋₂₀,-aril-C₆₋₂₀-alquilo-C₁₋₁₂, -aril-C₆₋₂₀-O-alquilo-C₁₋₁₂, -heteroarilo-C₃₋₂₀, -heteroaril-C₃ ...

POLYNUCLEAR COMPLEX

Disclosed is a polynuclear complex represented by the following formula (I). (In the formula (I), M represents a group 11 metal atom or a metal ion, a represents a number of not less than 2, and a plurality of M's may be the same as or different from each other; Ar represents a tetravalent organic group including an aromatic ring, b represents a number of not less than 1, and when there are a plurality of Ar's, they may be the same as or different from each other; R represents an optionally substituted hydrocarbon group, and a plurality of R's may be the same as or different from each other; Q represent a ligand having a coordinating atom selected from the group consisting of a nitrogen atom, a phosphorus atom, an oxygen atom and a sulfur atom, c represents a number of not less than 0, and when there are a plurality of Q's, they may be the same as or different from each other; and X represents a counter ion, d represents a number of not less than 0, and when there are a plurality of X's ...

THE PREPARATION OF METAL ALKYLS

A method of preparing a metal alkyl of formula (R3M)x where R3 represents three alkyl groups R which may be the same or different, M represents a Group III metallic element and x is 1 or 2, which method comprises (a) forming a trialkyl adduct of formula (R3M)y.L wherein L represents an aryl-containing Group V, preferably phosphorus, donor ligand provided by an organic Lewis base which is stable at 20oC, and wherein y is an integer equal to the number of Group V atoms presents in the ligand, and (b) heating the adduct to provide thermal dissociation thereof thereby releasing the alkyl as a gaseous product.

Emissive metal complexes

Monomeric metal complexes having desirable luminescence properties are provided. In one embodiment, a monomeric metal compound is represented by the formula (ArN)M(L)x, where ArN is an arylamido ligand, and M may be any metal capable of exhibiting luminescent properties, for example, a d10 metal. L may be a tertiary phosphine.

Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation

Non-C₂-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C₂-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.

Complex compounds having tetradentate ligands and the use thereof in the opto-electronic field

The invention describes electronic devices comprising a metal complex compound having at least one tetradentate ligand having N and/or P donors, in particular a ligand having a PPPP, NNNN, PNNP or NPPN structure, and uses of a complex of this type in the electronic field and for the generation of light.

Luminescent metal complexes for organic electronic devices

The present invention relates to auxiliary ligands for luminescent metal complexes, particularly emitter complexes having such auxiliary ligands, and particularly light-emitting devices, and particularly organic light-emitting devices (OLED) having metal complexes, which have the auxiliary ligands according to the invention.

Homogeneous Asymmetric Hydrogenation Process

Provide that a useful catalyst for homogeneous hydrogenation, particularly a catalyst for homogeneous asymmetric hydrogenation for hydrogenation, particularly asymmetric hydrogenation, which is obtainable with comparative ease and is excellent in economically and workability, and a process for producing a hydrogenated compound of an unsaturated compound, particularly an optically active compound using said catalyst with a high yield and optical purity.

TRANSITION METAL COMPLEX HAVING DIPHOSPHINE COMPLEX AS LIGAND

A transition metal complex having 2,2'-bis[bis(3,5-di-tert-butyl-4-methoxyphenyl)phosphino]-1,1'-binaphthyl as a ligand. The presence of the transition metal complex in the reaction system of an asymmetric reaction system allows the preparation of an objective compound having an objective absolute configuration with improved efficiency.

СПОСОБ ПОЛУЧЕНИЯ СОЕДИНЕНИЯ, СОЕДИНЕНИЯ, КОМПЛЕКСНЫЙ МЕТАЛЛООРГАНИЧЕСКИЙ КАТАЛИЗАТОР

Настоящее изобретение относится к новым соединениям, пригодным для использования в химической промышленности, формул (I)-(IV)где Е выбран из -BR9R10, -CR11R12OH, -COR11; -SiR11R12R13; -SiR11R12-CH-PR7R8; R9 и R10 представляют собой галоген, гидроксил, алкилокси, арилокси, циклоалкилокси, алкил и циклоалкил; R11, R12 и R13 представляют собой атом водорода, алкил, циклоалкил и арил; R1 и R2 представляют собой алкил, циклоалкил, арил, алкилокси, циклоалкилокси, арилокси, алкиламино, циклоалкиламино, ариламино, металлоценильную группы; R3, R4, R5, R6 представляют собой атом водорода, алкилокси, циклоалкилокси, арилокси, алкиламино, циклоалкиламино и ариламиногруппы; причем алкильная группа как таковая или как часть другого заместителя включает от 1 до 12 атомов углерода, арильная группа как таковая или как часть другого заместителя содержит от 5 до 20 атомов в кольце, циклоалкоксильная группа как таковая или как часть другого заместителя содержит 3, 5 или 6 атомов в кольце; X представляет собой ...

ФОСФИНОВЫЙ КОМПЛЕКС ВАНАДИЯ, КАТАЛИТИЧЕСКАЯ СИСТЕМА, СОДЕРЖАЩАЯ УКАЗАННЫЙ ФОСФИНОВЫЙ КОМПЛЕКС ВАНАДИЯ, И СПОСОБ (СО)ПОЛИМЕРИЗАЦИИ СОПРЯЖЕННЫХ ДИЕНОВ

Изобретение относится к каталитической системе для (co)полимеризации сопряженных диенов. Каталитическая система включает: (a) по меньшей мере один фосфиновый комплекс ванадия, имеющий общую формулу (I) или (II): V(X)[P(R)(R)](I), V(X)[(R)P(R)P(R)] (II), где X представляет собой анион, выбранный из галогена, такого как хлор, бром, йод; R, одинаковые или отличающиеся друг от друга, представляют собой атом водорода или выбраны из алкильных групп C-C, линейных или разветвленных, и С-Сциклоалкильных групп, n целое число в диапазоне от 0 до 3; R, одинаковые или отличающиеся друг от друга, выбраны из арильных групп, представляющих собой карбоциклические ароматические группы, выбранные из фенила, нафтила, фенантрена и антрацена; R, одинаковые или отличающиеся друг от друга, представляют собой атом водорода или выбраны из алкильных групп C-C, линейных или разветвленных, С-Сциклоалкильных групп и арильных групп, представляющих собой карбоциклические ароматические группы, выбранные из фенила, нафтила ...

ФОСФИНОВЫЙ КОМПЛЕКС ВАНАДИЯ, КАТАЛИЧЕСКАЯ СИСТЕМА, СОДЕРЖАЩАЯ УКАЗАННЫЙ ФОСФИНОВЫЙ КОМПЛЕКС ВАНАДИЯ, И СПОСОБ (СО)ПОЛИМЕРИЗАЦИИ СОПРЯЖЕННЫХ ДИЕНОВ

МЕТАЛЛИРОВАННЫЙ ЛИГАНД, КАТАЛИТИЧЕСКАЯ КОМПОЗИЦИЯ И ИХ ПРИМЕНЕНИЕ ПРИ ОЛИГОМЕРИЗАЦИИ ЭТИЛЕНА

INTEGRIERTES VERFAHREN ZUR HERSTELLUNG VON DIEN-KOMPLEXEN

Pseudozufallspolymer aus Alpha-Olefine und ein polymerisierendes Vinylidinemonomer

Process for the carbonylation of ethylenically unsaturated compounds

Metal complexes and organic electroluminescent devices

Metal complexes characterized by having a metal complex structure permitting luminescence from the triplet excited state and a monovalent group represented by the general formula (1) or (2); and luminescent devices made by using the same. The metal complexes are superior to luminescent materials of the prior art in luminous efficiency and can form luminescent layers by coating. (1) [wherein A is arylene or the like; R<1> and R<2> are each independently halogeno or the like; R<3> is alkyl or the like; a is an integer of 0 to 3; and b is an integer of 0 to 4] (2) [wherein D is arylene or the like; R<4> and R<5> are each independently halogeno or the like; and c and d are each an integer of 0 to 4.].

Metal complex and organic light-emitting device

SULFONIERTE PHENYLPHOSPHANE ABSTENTION COMPLEX CONNECTIONS

STRONGLY RESPONSIBLE ONE SURFACE COATINGS

PSEUDO RANDOM POLYMER FROM ALPHA OLEFINE AND A POLYMERIZING VINYLIDINEMONOMER

C1-SYMMETRICAL BISPHOSPHINLIGANDEN AND THEIR USE WITH THE ASYMMETRICAL SYNTHESIS OF PREGABALIN

PROCEDURE FOR THE PRODUCTION OF DIPHOSPHINVERBINDUNGEN AND INTERMEDIATE PRODUCTS FOR THE PROCEDURE

PROCEDURE FOR the HYDROGENATION of the EXOCYCLI GROUP OF GROUPCGROUPS of a 6-DEOXY-6-DEMETHYL-6-MEHTYLENTETRACYCLINS

GOLD CONNECTIONS, AT THE SAME TIME WITH IN ONES AND ZWEIZÄHNIGEN THE PHOSPHINEN COORDINATED ARE AND AN ANTI-TUMOR EFFECT EXHIBITING

BIDENTATE ORGANOPHOSPHORLIGANDEN AND YOUR USE

A PHOSPHA-ADAMANTANE (S) CATALYTIC SYSTEM

SYNTHESIS OF NON-C2-SYMMETRIC BISPHOSPHINE LIGANDS AS CATALYSTS FOR ASYMMETRIC HYDROGENATION

Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.

ANTITUMOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUMORS EMPLOYING [.alpha.,W- BIS(DISUBSTITUTEDPHOSPHINO)HYDROCARBON] DIGOLD (I) DIGOLD (III), DISILVER (I) AND DICOPPER (I) DERIVATIVES

ANTI TUMOR PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING TUMORS EMPLOYING ¢.alpha.,.omega.-BIS(DISUBSTITUTEDPHOSPHINO)- HYDROCARBON! DIGOLD(I), DIGOLD(III), DISILVER(I) AND DICOPPER(I) DERIVATIVES Pharmaceutical compositions and a method for treating tumors by administering an effective tumor cell growth-inhibiting amount of a ¢.alpha.,.omega.-bis(disubstituted-phosphino)hydrocarbon! digold(I), digold(III), disilver(I) or dicopper(I) derivative to an animal afflicted by such tumor cells.

TRANSITION METAL COMPOSITION

A transition metal composition has the formula: TiCl3(AlRxX3-x)nEaL? where E is an ether or thioether; L is an organic phosphorus- containing Lewis Base; and a and b are each greater than 0.001 and not more than 0.50. The composition has a low surface area, typically less than 50 m2/g. The composition can be prepared by reacting titanium tetrachloride with an organoaluminum compound, optionally heating the reaction product, contacting the reaction product at an elevated temperature with at least one of E and L and washing the product subsequent to the contacting with E. In the composition, E is conveniently di-n-butyl ether or di-isoamyl ether and L can be an organic phosphine, phosphine oxide, phosphite or phosphate. The composition can be used in a polymerisation catalyst to polymerise or copolymerise olefins monomers. Copolymers having an advantageous combination of low temperature brittle point and Flexural Modulus are disclosed.

PROCESS FOR PRODUCTION OF PHOSPHINE-BORANE COMPLEXES

A process for the production of phosphine-borane complexes represented by the general formula (I) or salts thereof: [wherein R1, R2 and R3 are each independently hydrogen, halogeno, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl, or an optionally substituted heterocyclic group (with the proviso that R1 and R2 together with the adjacent phosphorus atom may form a 4- to 6-membered ring)], characterized by converting a compound represented by the general formula (II) in a solvent in the presence of a borane reagent: [wherein each symbol is as defined above].

INORGANIC LITHIUM SALT COMPLEXES AND METHOD OF PREPARING THE SAME

TRIMERISATION AND OLIGOMERISATION OF OLEFINS USING A CHROMIUM BASED CATALYST

The invention provides a mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms, of which at least one heteroatom is nitrogen and at least two heteroatoms are not the same.The invention also provides a multidentate mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms. At least one heteroatom may be nitrogen and at least 2 heteroatoms may not be the same.

(6r, 10r) - 6.10, 14 - trimetilpentadekan - 2 - one, obtained from 6.10 - dimetilundets - 5 - en - 2 - one or 6.10 - dimetilundeka - 5, 9 - diene - 2 - one

Novel compound and organic device employing same

A compound represented by the general formula has excellent properties as a charge transport material [in the formula, R1-R3 represent substituents, n1 and n2 represent an integer of 0-5, n3 represents an integer of 0-4, X represents a linking group represented by -O-,-S-, -SO2-, -CS-, -R4-, -C(R5)(R6)-, -PO(R7)-, -Si(R8)(R9)-, >PO-, >Si(R10)-, or >Si< represents a linking group, m represents an integer of 2-4, R4 represents an aliphatic cyclic linking group, and R5-R10 represent a hydrogen atom, alkyl group, aryl group, or the like].

METHOD FOR PRODUCING PHOSPHINE BUTADIENE, COPPER COMPLEXES THEREOF, AND USE THEREOF IN CATALYSIS

NEW FUNCTIONAL DENDRIMERES HAVE PHOSPHORATED TERMINATIONS AND THEIR METHOD OF PREPARATION

인광 ＯＬＥＤ 물질로서 티아졸 및 옥사졸 카르벤 금속 착물

... 본 발명은 헤테로시클릭 카르벤 리간드를 포함하는 화합물에 관한 것이다. 특히, 통상의 이미다졸 카르벤 대신에 옥사졸 또는 티오아졸 카르벤이 사용된다. 이러한 화합물은 OLED에 사용되어 개선된 성질, 예컨대 안정성 및 색상-조정을 갖는 디바이스를 제공할 수 있다. 추가로, 헤테로시클릭 카르벤 금속 착물을 합성하기 위한 신규한 방법이 제공된다.

LUMINESCENT METAL COMPLEXES FOR ORGANIC ELECTRONIC DEVICES

The present invention relates to auxiliary ligands for luminescent metal complexes, particularly emitter complexes having such auxiliary ligands, and particularly light-emitting devices, and particularly organic light-emitting devices (OLED) having metal complexes, which have the auxiliary ligands according to the invention. COPYRIGHT KIPO & WIPO 2010 ...

DIHALIDE GERMANIUM(Ⅱ) PRECURSORS FOR GERMANIUM-CONTAINING FILM DEPOSITIONS

포스핀 바나듐 착물, 포스핀 바나듐 착물을 포함하는 촉매 시스템, 및 콘주게이트된 디엔을 (공)중합시키는 방법

... 본 발명은 하기 일반식 (I) 또는 일반식 (II)를 갖는 바나듐 포스핀 착물에 관한 것이다: 상기 식에서, - X는 할로겐, 예를 들어, 염소, 브롬, 요오드, 바람직하게, 염소로부터 선택된 음이온을 나타내거나, 티오시아네이트, 이소시아네이트, 설페이트, 산 설페이트, 포스페이트, 산 포스페이트, 카복실레이트, 디카복실레이트로부터 선택되며; - R1은, 이러한 것들 간에 동일하거나 상이하게, 수소 원자, 또는 알릴 기(CH2=CH-CH2-)를 나타내거나, 선형 또는 분지형 알킬 기 C1-C20, 바람직하게, C1-C15, 임의적으로 할로겐화된, 임의적으로 치환된 사이클로알킬 기로부터 선택되며; - n은 0 내지 3 범위의 정수이며; - R2는 이러한 것들 간에 동일하거나 상이하게, 임의적으로 치환된 아릴 기로부터 선택되며; - R3은 이러한 것들 간에 동일하거나 상이하게, 수소 원자, 또는 알릴 기(CH2=CH-CH2-)를 나타내거나, 선형 또는 분지된, 알킬 기 C1-C20, 바람직하게, C1-C15, 임의적으로 할로겐화된, 임의적으로 치환된 사이클로알킬 기, 치환되거나 비치환된 아릴 기로부터 선택되며; - R4는 기 -NR5를 나타내며, 여기서, R5는 수소 원자를 나타내거나, 선형 또는 분지형 C1-C20 알킬 기, 바람직하게, C1-C15로부터 선택되거나; R4는 알킬렌 기 -(CH2)p-를 나타내며, 여기서, p는 1 내지 5 범위의 정수를 나타내며, 단, 일반식 (I)에서, n이 1이며 R1이 메틸인 경우에, R2는 페닐과 상이하다. 상기 일반식 (I) 또는 일반식 (II)를 갖는 포스핀 바나듐 착물은 콘주게이트된 디엔의 (공)중합을 위한 촉매 시스템에서 유리하게 사용될 수 있다.

Organic electroluminescence element and compound used therefor

An organic electroluminescence element using a monospirobifluorene compound represented by general formula in a light-emitting layer exhibits a high emission efficiency. At least one of R1 through R8 represents an electron-donating group, with the rest representing hydrogen atoms; at least one of R9 through R16 represents an electron-withdrawing group other than a triazino group, with the rest representing hydrogen atoms; and the number of symbols R1 through R16 which represent hydrogen atoms is between 11 and 14, inclusive.

THERMALLY ACTIVATED FLUORESCENCE AND SINGLET HARVESTING WITH RIGID METAL COMPLEXES FOR OPTOELECTRONIC DEVICES

The invention relates to mononuclear metal complexes containing Cu or Ag as the metal ion, a chromophore ligand and a ligand of formula II, where: R1 to R26 are independently of one another H, alkyl, aryl, heteroaryl, halide, silyl (-SiR'R''R'''), alkoxyl (-OR'), carboxyl (-COR'), thioalkoxyl (-SR'), phosphanyl (-PR'R'') or amine (-NR'R''), substituted alkyl, aryl or heteroaryl (preferably substituted with further alkyl, aryl, heteroaryl, alkoxy, carboxy, thioalkoxy, phosphanyl, amine groups or halogenated), wherein the radicals R1 to R26 can also be linked to one another; R', R'' and R''' are independently of one another H, alkyl, aryl, heteroaryl or also substituted (preferably halogenated, substituted with OCH3, N(CH3)2, P(C6H5)2, CO2CH3, COCH3, CONCH3, NO2, SCH3) alkyl, aryl or heteroaryl; where each # indicates the coordinating position on the metal ion M.

RUTHENIUM CARBENE COMPLEXES FOR OLED MATERIAL

Neutral ruthenium (II) complexes having at least one bidentate carbene coordinated to the ruthenium through a ruthenium-carbene bond are provided. Also provided are organic light emitting devices comprising the ruthenium (II) carbene complexes.

AROMATIC AZA-BICYCLIC COMPOUNDS COMPRISING CU, AG, AU, ZN, AL FOR USE IN ELECTROLUMINESCENT DEVICES

The present invention relates to metal complexes and electronic devices, in particular organic electroluminescent devices such as OLEDs, containing said metal complexes. The following compounds of formula (1) are claimed: M(L)n(L')m, the compound of general formula (1) containing a sub-structure M(L)n of formula (2) and L representing a mono-anionic ligand. Formula (2). The variables are defined as follows: M represents Cu, Ag, Au, Ru, Zn, Al, Ga or In; A represents a co-ordinating group which co-ordinates with M and can be substituted with one or more substituents R; the other variables are defined as cited in the claims.

ORGANIC LIGHT EMITTING DEVICE MATERIAL AND ORGANIC LIGHT EMITTING DEVICE

The present invention provides phosphorescent materials and polymer phosphorescent materials that generate lights of various colors including blue, green, yellow, orange and red, which are useful for high performance multicolor organic light-emitting EL devices, and also provides an organic light emitting device material containing a gold complex represented by formulae such as (2) and (6) below (symbols in the formulae are as described in the specification) in which gold is bonded to at least one atom selected from carbon, oxygen and sulfur, and organic light-emitting EL device including the material in its light-emitting layer.

RHENIUM CONTAINING HYDROSILYLATION CATALYSTS AND COMPOSITIONS CONTAINING THE CATALYSTS

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition ' capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

TERNARY LIGAND COMPLEXES USEFUL AS RADIOPHARMACEUTICALS

The present invention provides novel radiopharmaceuticals useful for imaging the heart, brain, lungs, liver or kidneys, kits useful for preparing the radiopharmaceuticals, and methods of imaging the heart, brain, lungs, liver or kidneys in a patient in need of such imaging. The radiopharmaceuticals are comprised of technetium or rhenium radionuclide complexes of a ternary ligand system: one hydrazido or diazenido ligand, one aminoalcohol ligand, and one pi-acid ligand selected from phosphines, arsines, and imine nitrogen-containing heterocyles. The radiopharmaceuticals have the formula ML1L2L3, wherein the variables are as defined herein.

Organometallic compounds

Organometallic compounds containing a phosphoamidinate ligand are provided. Such compounds are particularly suitable for use as vapor deposition precursors. Also provided are methods of depositing thin films, such as by ALD and CVD, using such compounds.

Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation

Non-C2-symmetric bisphospholane ligands and methods for their preparation are described. Use of metal/non-C2-symmetric bisphospholane complexes to catalyze asymmetric transformation reactions to provide high enantiomeric excesses of formed compounds is also described.

CANCER CELL-CONTAINING COMPOSITION

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer. 2: The cancer cell composition of claim 1 , wherein Rand Rare the same claim 1 , and R claim 1 , R claim 1 , and Rare the same optionally substituted C-Calkyl group.3: The cancer cell composition of claim 2 , wherein Rand Rare methyls claim 2 , and R claim 2 , R claim 2 , and Rare selected from the group consisting of methyl claim 2 , ethyl claim 2 , and isopropyl.4: The cancer cell composition of claim 2 , wherein Rand Rare ethyls claim 2 , and R claim 2 , R claim 2 , and Rare methyls.520-. (canceled)21: The cancer cell composition of claim 1 , wherein Rand Rare methyls and R claim 1 , R claim 1 , and Rare ethyls.22: The cancer cell composition of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , and Rare each a methyl group. This application claims the priority of the filing date of the U.S. Provisional Patent Application No. 62/326,389 filed Apr. 22, 2016, the disclosure of which is hereby incorporated herein by reference in its entirety.This project was funded by the National Plan for Science and Innovation (MARIFAH)—King Abdulaziz City for Science and Technology (KACST) through the Science and Technology Unit at King Fahd University of Petroleum and Minerals (KFUPM) of Saudi Arabia, award No. 14-MED64-04.The present disclosure relates to therapeutic gold(I) complexes, a pharmaceutical composition thereof, and a method of treating cancer.The “background” description provided herein is for the purpose of generally presenting the context of the disclosure. Work of the presently named inventors, to the extent it is described in this background section, as well as aspects of the description which may not otherwise ...

Copper complexes and their use

The invention relates to copper complexes of phosphorus compounds, to a process for their preparation and to their use in catalytic coupling reactions.

Organometallic compounds for chemical vapour deposition and atomic layer deposition of thin films

Organometallic compounds containing a phosphoamidinate ligand are provided. Such compounds are particularly suitable for use as vapor deposition precursors. Also provided are methods of depositing thin films, such as by ALD and CVD, using such compounds.

Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith

Phosphine gold compounds

Compounds of formula (I) and (III) wherein R is phenyl; R1 is phenyl or -AP(AuX) (R)2; A is the same and is a straight or branched alkanediyl chain of from one to six carbon atoms; n is 0 or 1; m is the same and is 0 or 1; and X is the same and is halo or thiosugar; provided that when n is 1, R1 is phenyl; compositions containing them and their use in therapy for inhibiting the growth of animal tumor cells.

POLYNUCLEAR COMPLEX

PROBLEM TO BE SOLVED: To provide an inexpensive metal complex useful as a light-emitting material. SOLUTION: Disclosed is a polynuclear complex represented by formula (I) (in the formula (I), M is a group 11 metal atom or metal ion; (a) is a number of ≥2; Ar is a tetravalent organic group; b is a number of ≥1; R is a hydrocarbon group; Q is a ligand having a coordinating atom selected from the group consisting of a nitrogen atom, a phosphorus atom, an oxygen atom and a sulfur atom; c is a number of ≥0; X is a counter ion; and d is a number of ≥0). COPYRIGHT: (C)2009,JPO&INPIT ...

ポリマーナノ粒子

Галогенсодержащее соединение и его применение, состав катализатора и способы олигомеризации, тримеризации и тетрамеризации этилена

Изобретение относится к галогенсодержащему соединению, представленному формулой I, в котором в формуле I R1, R2, R3 и R4 являются одинаковыми или разными и каждый независимо представляет собой хлор или фтор, при этом все из R1, R2, R3 и R4 представляют собой орто-заместители; R5 и R6 являются одинаковыми или разными, и каждый независимо представляет собой водород, С1-С12 алкил, С3-С12 циклоалкил, фенил, метилфенил, этилфенил или хлорфенил. Также предложено применение указанного галогенсодержащего соединения в качестве лиганда в составе катализатора для олигомеризации этилена, состав катализатора для олигомеризации этилена, содержащий указанное галогенсодержащее соединение, и способы олигомеризации, тримеризации и тетрамеризации этилена с использованием указанного состава катализатора. Изобретение позволяет значительно улучшить активность и селективность в реакции олигомеризации этилена, в частности в реакциях тримеризации этилена и тетрамеризации этилена, и значительно снизить образование ...

ORGANOGOLD COMPLEXES AND METHODS FOR MAKING THE SAME

The present invention relates to chiral ligands deriving from α- and β-amino acids, and from metal complexes formed from the same. The ligands are useful with catalytic gold complexes, particularly Au(I) complexes. 12. A compound as defined in any preceding claim , wherein the Au is Au(I).13. A compound as defined in any preceding claim wherein A denotes SOor C(═O).14. A compound as defined in any preceding claim wherein R denotes C-C-alkyl , C-C-fluoroalkyl; or phenyl optionally substituted with 1 to 5 R15. A compound as defined in any preceding claim wherein A-R denotes SOCH , SOC-C-perfluoroalkyl , SOCHMe , SOCHNOor COCHBr.16. A compound as defined in any preceding claim wherein A-R denotes SOCH , SOCF , SOCHMe , SOCHNOor COCHBr.17. A compound as defined in any preceding claim wherein L denotes P(R) , S(R)or N(R).18. A compound as defined in any preceding claim wherein L denotes P(R).19. A compound as defined in any preceding claim wherein L denotes P(R); and Rdenotes CH , CH; or phenyl optionally substituted with 1 to 5 R.20. A compound as defined in any preceding claim wherein L denotes P(R); and Rdenotes phenyl optionally substituted with 1 to 5 R.21. A compound as defined in any preceding claim wherein Rdenotes C-C-alkyl.22. A compound as defined in any preceding claim wherein Rdenotes methyl.23. A compound as defined in any preceding claim wherein Rdenotes C-C-alkyl.24. A compound as defined in any preceding claim wherein Rdenotes methyl25. A compound as defined in any preceding claim wherein Rdenotes H or C-C-alkyl26. A compound as defined in any preceding claim wherein v denotes 1; and t denotes an integer from 2 to 4.27. A compound as defined in any preceding claim wherein v denotes 1; and t denotes 2.2825. A compound as defined in any of - wherein v denotes 0.29. A compound as defined in any preceding claim wherein u denotes 0.3028. A compound as defined in any of - wherein u denotes 1.31. A compound as defined in any preceding claim wherein Rdenotes ...

METHODS OF FORMING SINGLE SOURCE PRECURSORS, METHODS OF FORMING POLYMERIC SINGLE SOURCE PRECURSORS, AND SINGLE SOURCE PRECURSORS FORMED BY SUCH METHODS

Methods of forming single source precursors (SSPs) include forming intermediate products having the empirical formula ½{LN(μ-X)M′X}, and reacting MER with the intermediate products to form SSPs of the formula LN(μ-ER)M′(ER), wherein L is a Lewis base, M is a Group IA atom, N is a Group IB atom, M′ is a Group IIIB atom, each E is a Group VIB atom, each X is a Group VIIA atom or a nitrate group, and each R group is an alkyl, aryl, vinyl, (per)fluoro alkyl, (per)fluoro aryl, silane, or carbamato group. Methods of forming polymeric or copolymeric SSPs include reacting at least one of HEREH and MER with one or more substances having the empirical formula LN(μ-ER)M′(ER)or LN(μ-X)M′(X)to form a polymeric or copolymeric SSP. New SSPs and intermediate products are formed by such methods. 1. A method of forming a copolymeric single source precursor , comprising reacting a first single source precursor , a second single source precursor differing from the first single source precursor , and HEREH to form a copolymeric single source precursor having the empirical formula {[LN(ER)(μ-ERE)M′(ER)(ERE)][LN(ER)(μ-ERE)M′(ER)(ERE)]} , wherein L is a Lewis base , each Nand Nis individually selected from Group IB atoms , each M′and M′is individually selected from Group IIIA atoms , each E and Eis individually selected from Group VIA atoms , a is any number from zero (0) to two (2) , b is the difference between two (2) and a , c is any number from zero (0) to two (2) , d is the difference between two (2) and c , e is any number from zero (0) to two (2) , f is the difference between two (2) and e , g is any number from zero (0) to two (2) , h is the difference between two (2) and g , m is any number , n is any number , l is any number , each R is individually selected from the group consisting of alkyl , aryl , vinyl , (per)fluoro alkyl , (per)fluoro aryl , silane , and carbamato groups , and each Ris individually selected from the group consisting of α ,ω-Efunctionalized alkyl , aryl , ...

Ultrastable Silver Nanoparticles

Ultrastable silver nanoparticles, methods of making the same, and methods of using the same, are disclosed. 1. A compound comprising the formula MAg(SR)wherein:M is a metal selected from the group consisting of Cs, Na, K, Li, Fr, and Rb; andSR is a mercaptophenyl ligand;and salts, isomers, stereoisomers, entantiomers, racemates, solvates, hydrates, polymorphs, and prodrugs thereof.2. The compound of claim 1 , wherein the mercaptophenyl ligand is selected from the group consisting of p-mercaptobenzoic acid claim 1 , p-mercaptophenyl alcohol claim 1 , and 4-mercaptophenol.3. (canceled)4. The compound of claim 1 , further comprising coordinating molecules selected from the group consisting of: deprotonated methanol ions claim 1 , deprotonated ethanol ions claim 1 , hydroxide ions claim 1 , citrate claim 1 , acetate claim 1 , DMSO claim 1 , DMF claim 1 , pyridine claim 1 , ammonia claim 1 , acetone claim 1 , acetonitrile claim 1 , ethers claim 1 , phosphines claim 1 , and combinations thereof.5. The compound of claim 4 , wherein the compound has a core comprising coordination sites claim 4 , and the coordinating molecules stabilize the compound by binding to the coordination sites.6. The compound of claim 5 , wherein one or more of the coordinating molecules is substituted by one or more of a pharmaceutical agent claim 5 , a fluorophore claim 5 , or a carbohydrate claim 5 , covalently bonded through a sulfur linkage at a coordination site.7. The compound of claim 1 , wherein the compound comprises a Agcore and a protecting layer of AgScapping structures.8. A silver cluster molecule comprising: a 32-silver-atom dodecahedral core consisting of a 12-silver-atom icosahedron encapsulated by a 20-silver-atom dodecahedron; and 30 coordinating ligands.9. The silver cluster molecule of claim 8 , wherein the coordinating ligands comprise p-MBA.10. The silver cluster molecule of claim 8 , wherein the dodecahedral core comprises icosahedral symmetry.11. The silver cluster molecule ...

Butyl-bridged diphosphine ligands for alkoxycarbonylation

The invention relates to compounds of formula (I) where R 1 , R 2 , R 3 , R 4 are each independently selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl, —(C 3 -C 20 )-heteroaryl; at least one of the R 1 , R 2 , R 3 , R 4 radicals is a —(C 3 -C 20 )-heteroaryl radical; and R 1 , R 2 , R 3 , R 4 , if they are —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl or —(C 3 -C 20 )-heteroaryl, may each independently be substituted by one or more substituents selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —O—(C 1 -C 12 )-alkyl, —O—(C 1 -C 12 )-alkyl-(C 6 -C 20 )-aryl, —O—(C 3 -C 12 )-cycloalkyl, —S—(C 1 -C 12 )-alkyl, —S—(C 3 -C 12 )-cycloalkyl, —COO—(C 1 -C 12 )-alkyl, —COO—(C 3 -C 12 )-cycloalkyl, —CONH—(C 1 -C 12 )-alkyl, —CONH—(C 3 -C 12 )-cycloalkyl, —CO—(C 1 -C 12 )-alkyl, —CO—(C 3 -C 12 )-cycloalkyl, —N—[(C 1 -C 12 )-alkyl] 2 , —(C 6 -C 20 )-aryl, —(C 6 -C 20 )-aryl-(C 1 -C 12 )-alkyl, —(C 6 -C 20 )-aryl-O—(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl, —(C 3 -C 20 )-heteroaryl-(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl-O-(C 1 -C 12 )-alkyl, —COOH, —OH, —SO 3 H, —NH 2 , halogen; and to the use thereof as ligands in alkoxycarbonylation.

PROCESS FOR THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS WITH MONOPHOSPHINE LIGANDS

The invention relates to a process comprising the following process steps: 2. Process according to claim 1 ,{'sup': '1', 'sub': 1', '12', '6', '20', '3', '12', '3', '20, 'wherein Ris selected from —(C-C)-alkyl, —(C-C)-aryl, —(C-C)-cycloalkyl, —(C-C)-heteroaryl.'}3. Process according to claim 1 ,{'sup': '2', 'sub': 6', '20', '3', '12', '3', '20, 'wherein Ris selected from —(C-C)-aryl, —(C-C)-cycloalkyl, —(C-C)-heteroaryl.'}4. Process according to claim 1 ,{'sup': 1', '2, 'sub': 3', '20, 'wherein Rand R, if they are —(C-C)-heteroaryl, are selected from heteroaryl groups having five to ten ring atoms.'}5. Process according to claim 1 ,{'sup': 1', '2, 'sub': 3', '20, 'wherein Rand R, if they are —(C-C)-heteroaryl, are selected from furyl, thienyl, pyrrolyl, imidazolyl, pyridyl, pyrimidyl, indolyl.'}6. Process according to claim 1 ,{'sup': '3', 'wherein Ris selected from heteroaryl groups having five to ten ring atoms.'}7. Process according to claim 1 ,{'sup': '3', 'wherein Ris selected from furyl, thienyl, pyrrolyl, imidazolyl, pyridyl, pyrimidyl, indolyl.'}8. Process according to claim 1 ,{'sup': 1', '2', '3, 'sub': 1', '12', '6', '20', '6', '20', '1', '12', '6', '20', '1', '12, 'wherein R, Rand Rmay each independently be substituted by one or more substituents selected from —(C-C)-alkyl, —(C-C)-aryl, —(C-C)-aryl-(C-C)-alkyl, —(C-C)-aryl-O—(C-C)-alkyl.'}10. Process according to claim 1 ,wherein the ethylenically unsaturated compound is selected from ethene, propene, 1-butene, cis- and/or trans-2-butene, isobutene, 1,3-butadiene, 1-pentene, cis- and/or trans-2-pentene, 2-methyl-1-butene, 3-methyl-1-butene, 2-methyl-2-butene, hexene, tetramethylethylene, heptene, 1-octene, 2-octene, di-n-butene, and mixtures thereof.11. Process according to claim 1 ,wherein the ethylenically unsaturated compound comprises 8 to 12 carbon atoms.12. Process according to claim 1 ,wherein the compound comprising Pd in process step b) is selected from palladium dichloride, palladium(II) ...

Process for the alkoxycarbonylation of alcohols

The invention relates to a process comprising the following process steps: a) introducing a first alcohol, the first alcohol having 2 to 30 carbon atoms; b) adding a phosphine ligand and a compound which comprises Pd, or adding a complex comprising Pd and a phosphine ligand; c) adding a second alcohol; d) supplying CO; e) heating the reaction mixture, the first alcohol reacting with CO and the second alcohol to form an ester; where the phosphine ligand is a compound of formula (I) where m and n are each independently 0 or 1; R 1 , R 2 , R 3 , R 4 are each independently selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl, —(C 3 -C 20 )-heteroaryl; at least one of the R 1 , R 2 , R 3 , R 4 radicals is a —(C 3 -C 20 )-heteroaryl radical; and R 1 , R 2 , R 3 , R 4 , if they are —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl or —(C 3 -C 20 )-heteroaryl, may each independently be substituted by one or more substituents selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —O—(C 1 -C 12 )-alkyl, —O—(C 1 -C 12 )-alkyl-(C 6 -C 20 )-aryl, —O—(C 3 -C 12 )-alkyl, —S—(C 1 -C 12 )-alkyl, —S—(C 3 -C 12 )-cycloalkyl, —COO—(C 1 -C 12 )-alkyl, —COO—(C 3 -C 12 )-cycloalkyl, —CONH—(C 1 -C 12 )-alkyl, —CONH—(C 3 -C 12 )-cycloalkyl, —CO—(C 1 -C 12 )-alkyl, —CO—(C 3 -C 12 )-cycloalkyl, —N—[(C 1 -C 12 )-alkyl] 2 , —(C 6 -C 20 )-aryl, —(C 6 -C 20 )-aryl-(C 1 -C 12 )-alkyl, —(C 6 -C 20 )-aryl-O—(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl, —(C 3 -C 20 )-heteroaryl-(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl-O—(C 1 -C 12 )-alkyl, —COON, —OH, —SO 3 H, —NH 2 , halogen.

1, 1' -bis(phosphino)ferrocene ligands for alkoxycarbonylation

Diastereomer mixture comprising diastereomers of the formulae (I.1) and (I.2) where R 2 , R 4 are each independently selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —(C 6 -C 20 )-aryl; the R 1 , R 3 radicals are each a —(C 3 -C 20 )-heteroaryl radical; R 1 , R 3 may each independently be substituted by one or more substituents selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —O—(C 1 -C 12 )-alkyl, —O—(C 1 -C 12 )-alkyl-(C 6 -C 20 )-aryl, —O—(C 3 -C 12 )-cycloalkyl, —S—(C 1 -C 12 )-alkyl, —S—(C 3 -C 12 )-cycloalkyl, —COO—(C 1 -C 12 )-alkyl, —COO—(C 3 -C 12 )-cycloalkyl, —CONH—(C 1 -C 12 )-alkyl, —CONH—(C 3 -C 12 )-cycloalkyl, —CO—(C 1 -C 12 )-alkyl, —CO—(C 3 -C 12 )-cycloalkyl, —N—[(C 1 -C 12 )-alkyl] 2 , —(C 6 -C 20 )-aryl, —(C 6 -C 20 )-aryl-(C 1 -C 12 )-alkyl, —(C 6 -C 20 )-aryl-O—(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl, —(C 3 -C 20 )-heteroaryl-(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl-O—(C 1 -C 12 )-alkyl, —COOH, —OH, —SO 3 H, —NH 2 , halogen; and R 2 , R 4 , if they are —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl or —(C 6 -C 20 )-aryl, may each independently be substituted by one or more substituents selected from —(C 1 -C 12 )-alkyl, —(C 3 -C 12 )-cycloalkyl, —(C 3 -C 12 )-heterocycloalkyl, —O—(C 1 -C 12 )-alkyl, —O—(C 1 -C 12 )-alkyl-(C 6 -C 20 )-aryl, —O—(C 3 -C 12 )-cycloalkyl, —S—(C 1 -C 12 )-alkyl, —S—(C 3 -C 12 )-cycloalkyl, —COO—(C 1 -C 12 )-alkyl, —COO—(C 3 -C 12 )-cycloalkyl, —CONH—(C 1 -C 12 )-alkyl, —CONH—(C 3 -C 12 )-cycloalkyl, —CO—(C 1 -C 12 )-alkyl, —CO—(C 3 -C 12 )-cycloalkyl, —N—[(C 1 -C 12 )-alkyl] 2 , —(C 6 -C 20 )-aryl, —(C 6 -C 20 )-aryl-(C 1 -C 12 )-alkyl, —(C 6 -C 20 )-aryl-O—(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl, —(C 3 -C 20 )-heteroaryl-(C 1 -C 12 )-alkyl, —(C 3 -C 20 )-heteroaryl-O—(C 1 -C 12 )-alkyl, —COOH, —OH, —SO 3 H, —NH 2 , halogen. The invention further relates to Pd complex mixtures ...

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

A compound having a structure according to formula (I) 2. The compound of claim 1 , wherein Y includes a carbene carbon that is coordinated to the Cu atom.3. The compound of claim 1 , wherein the ring formed from Xand Xis part of a polycyclic ring system.6. The compound of claim 1 , wherein Y is selected from the group consisting of aryl claim 1 , heteroalkyl claim 1 , and heteroaryl.8. The compound of claim 7 , wherein Yin formula (I) is selected from the group consisting of aryl claim 7 , heteroalkyl claim 7 , and heteroaryl.9. A consumer product including a display claim 1 , the display including an organic light emitting device comprising an anode claim 1 , a cathode claim 1 , and an organic layer disposed between the anode and the cathode claim 1 , the organic layer comprising a compound of and a host.10. The product of selected from the group consisting of flat panel displays claim 9 , computer monitors claim 9 , medical monitors claim 9 , televisions claim 9 , billboards claim 9 , lights for interior or exterior illumination and/or signaling claim 9 , heads up displays claim 9 , fully transparent displays claim 9 , flexible displays claim 9 , laser printers claim 9 , telephones claim 9 , cell phones claim 9 , personal digital assistants (PDAs) claim 9 , laptop computers claim 9 , digital cameras claim 9 , camcorders claim 9 , viewfinders claim 9 , micro-displays claim 9 , 3-D displays claim 9 , vehicles claim 9 , a wall claim 9 , theater or stadium screen claim 9 , and a sign.11. An organic light emitting device that includes an anode claim 1 , a cathode claim 1 , and an organic layer disposed between the anode and the cathode claim 1 , wherein the organic layer is an emissive layer that comprises a compound of and a host claim 1 , the compound being an emissive dopant.12. An organic light emitting device that includes an anode claim 1 , a cathode claim 1 , and an organic layer disposed between the anode and the cathode claim 1 , wherein the organic layer ...

Organic electroluminescent materials and devices

The present invention includes novel polycyclic alkyl amino carbenes as ligands for metal complexes. These compounds may be useful as emitter materials for phosphorescent electroluminescent devices.

ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES

Novel phosphorescent OLED emitters based on metal complexes with indolizine-derived heterocycles as ligands are disclosed. Structural variations of the ligands provide access to a variety of green, yellow and red emitters. 2. The compound of claim 1 , wherein two Rare joined to form a ring.3. The compound of claim 1 , wherein two Rare joined to form a ring.4. The compound of claim 1 , wherein R is linked to ring A or ring B by a direct bond.5. The compound of claim 1 , wherein M is Ir or Pt.6. The compound of claim 1 , wherein one of Zand Zis N claim 1 , and one of Zand Zis C.7. The compound of claim 1 , wherein ring A is selected from the group consisting of pyridine claim 1 , pyrimidine claim 1 , triazine claim 1 , imidazole claim 1 , pyrazole claim 1 , oxazole claim 1 , thiazole claim 1 , and imidazole derived carbene.8. The compound of claim 1 , wherein ring B is a benzene ring.9. The compound of claim 1 , wherein X-Xare each C.12. The compound of claim 1 , wherein the compound has a formula of M(L)(L)(L)wherein Land Lare each a bidentate ligand; and wherein x is 1 claim 1 , 2 claim 1 , or 3; y is 0 claim 1 , 1 claim 1 , or 2; z is 0 claim 1 , 1 claim 1 , or 2; and x+y+z is the oxidation state of the metal M.16. The OLED of claim 15 , wherein the organic layer is an emissive layer and the compound is an emissive dopant or a non-emissive dopant.17. The OLED of claim 15 , wherein the organic layer further comprises a host claim 15 , wherein the host comprises at least one chemical group selected from the group consisting of triphenylene claim 15 , carbazole claim 15 , dibenzothiphene claim 15 , dibenzofuran claim 15 , dibenzoselenophene claim 15 , azatriphenylene claim 15 , azacarbazole claim 15 , aza-dibenzothiophene claim 15 , aza-dibenzofuran claim 15 , and aza-dibenzoselenophene.20. A formulation comprising a compound according to . This application is a continuation of co-pending U.S. patent application Ser. No. 16/166,247, filed on Oct. 22, 2018, which ...

Materials for organic electroluminescent devices

The invention relates to mononuclear neutral copper(I) complexes with a bidentate ligand which is bonded via nitrogen and two phosphine or arsine ligands, to the use thereof for the production of electronic components, and to electronic devices comprising these complexes.

Gold complex-containing cancer activity composition

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES

Complexes and devices, such as organic light emitting devices and full color displays, including a compound of the formula: 2. (canceled)13. A light emitting device comprising the compound of .14. An OLED device comprising the compound of any one of .15. The OLED device of claim 14 , wherein the device is a phosphorescent OLED device.16. A photovoltaic device comprising the compound of .17. A luminescent display device comprising the compound of . This application claims priority to U.S. Ser. No. 62/037,802 entitled “NON-PLATINUM METAL COMPLEXES FOR EXCIMER BASED SINGLE DOPANT WHITE ORGANIC LIGHT EMITTING DIODES” and filed on Aug. 15, 2014, which is incorporated by reference herein in its entirety.This invention was made with government support under DE-EE0005075 awarded by the Department of Energy. The government has certain rights in the invention.This disclosure relates to non-platinum metal complexes for excimer based single dopant white organic light emitting diodes (OLEDs).Cyclometalated metal complexes can be used for many applications including the development of efficient and high quality organic white lighting devices. One route for achieving organic white lighting devices is development of singly doped white OLEDs by utilizing the excimer properties. Typically the metal complexes used as emissive materials are square-planar platinum complexes.White organic light emitting diodes (WOLEDs) have shown promise as a potential replacement for existing lighting technologies due to their efficiencies exceeding 100 Lm/W, potential for low cost and scalable production, and compatibility with flexible substrates. Through continuous improvements in device designs and by employing phosphorescent iridium or platinum emitters, WOLEDs with high efficiencies and high color quality have been achieved.Nevertheless, major challenges still remain, including the deficiency of an efficient and stable phosphorescent blue emitter and the cost prohibitive nature of typical ...

Organogold nonlinear optical chromophores

An organogold nonlinear optical chromophore includes gold(I) complexed with a benzothiazolyl-substituted fluorophore and optionally an organophosphine ligand or an N-heterocyclic carbene ligand.

PHOSPHOROUS COMPOUND AND TRANSITION METAL COMPLEX THEREOF

The present invention provides a phosphorous compound represented by general formula (1), and transition metal complexes containing such phosphorous compounds as ligands: 2. The phosphorous compound according to claim 1 , wherein Z is selected from the group consisting of an oxy group claim 1 , a thio group claim 1 , imino groups optionally having substitutent(s) claim 1 , methylene groups optionally having substitutent(s) claim 1 , and ethylene groups optionally having substitutent(s).3. The phosphorous compound according to which is an optically active substance.4. The phosphorous compound according to claim 1 , wherein Y is a lone electron pair.5. A transition metal complex comprising the phosphorous compound according to as a ligand.6. The transition metal complex according to claim 5 , comprising a transition metal selected from the group consisting of iron claim 5 , cobalt claim 5 , nickel claim 5 , copper claim 5 , ruthenium claim 5 , rhodium claim 5 , palladium claim 5 , silver claim 5 , osmium claim 5 , iridium claim 5 , platinum claim 5 , and gold. The present invention relates to a novel phosphorous compound and a transition metal complex containing the phosphorous compound as a ligand.Today, various transition metal complexes composed of transition metal species and ligands are used as catalysts of organic synthesis reactions. It is well known that not only transition metal species but also ligands of complexes play important roles as factors of exhibiting the performance or activity of such catalysts. For this reason, heretofore, numerous coordination compounds including phosphorous compounds have been developed as ligands. Furthermore, when an organic synthesis reaction is carried out using a complex catalyst, it is possible to construct optimum catalysts for a variety of substrates by appropriately combining transition metal species and ligands. Hence, the research and development are still actively conducted at present. It is needless to say that the ...

METHOD FOR PRODUCING TETRAKIS (TRIHYDROCARBYL PHOSPHANE) PALLADIUM(0)

Method for the production of tetrakis(trihydrocarbylphosphane)palladium(0) in organic solvent, whereby 50 to 100% by weight of the organic solvent consist of at least one polar-aprotic solvent, characterised in that a) at least one palladium compound selected from the group consisting of palladium(II) compounds and palladium(IV) compounds that are soluble in the organic solvent is reacted with b) at least one base, selected from the group consisting of alkali metal hydroxides, alkali metal carbonates, alkali metal hydrogen carbonates, alkali metal-C-C-alcoholates, ammonium carbonate, ammonium hydrogen carbonate, alkaline earth metal hydroxides, alkaline earth metal carbonates, alkaline earth metal hydrogen carbonates, alkaline earth metal-C-C-alcoholates, and alkylamines with a total of 2 to 12 carbon atoms; c) at least one trihydrocarbylphosphane; and d) at least one organic reducing agent that is different from the remaining components that are used in the method. 1. A method for the production of tetrakis(trihydrocarbylphosphane)palladium(0) in organic solvent , whereby 50 to 100% by weight of the organic solvent consist of at least one polar-aprotic solvent , whereina) at least one palladium compound selected from the group consisting of palladium(II) compounds and palladium(IV) compounds that are soluble in the organic solvent is reacted with{'sub': 1', '4', '1', '4, 'b) at least one base selected from the group consisting of alkali metal hydroxides, alkali metal carbonates, alkali metal hydrogen carbonates, alkali metal-C-C-alcoholates, ammonium carbonate, ammonium hydrogen carbonate, alkaline earth metal hydroxides, alkaline earth metal carbonates, alkaline earth metal hydrogen carbonates, alkaline earth metal-C-C-alcoholates, and alkylamines with a total of 2 to 12 carbon atoms;'}c) at least one trihydrocarbylphosphane; andd) at least one organic reducing agent that is different from the remaining components that are used in the method.2. The method of claim ...

METAL PHOSPHIDE NANOMATERIALS PREPARED FROM SINGLE SOURCE METAL AMIDES

The present invention provides a novel solution or route for metal phosphide (MP) nanomaterials from the thermal decomposition of metal bis[bis(diisopropylphosphino)amide], M[N(PPri)], and/or single-source precursors. Synthetic routes to MPnanomaterials may be used in energy applications including batteries, semiconductors, magnets, catalyst, lasers, inks, electrocatalysts and photodiodes. 194-. (canceled)95. A method of making nanomaterials comprising the steps of: solution processing a [M[N(PR)]]precursor to synthesize nanomaterials.96. The method of wherein R equals H.97. The method of wherein R is a linear or branched alkyl group and substituted analogs claim 95 , an aryl or substituted aryl claim 95 , a silyl alkyl or silyl aryl claim 95 , or mixtures thereof.98. The method of wherein said nanomaterials are MP.99. The method of wherein said nanomaterials are MP.100. The method of wherein x can vary from 0 to 5 depending on the valent state of the metal claim 95 , where x is chosen to balance the charges of said [M[N(PR)]]molecule; and/or wherein y can vary from about 1 to about 5.101. The method of wherein M is a metallic element selected from the group consisting of Groups 1-15 in the Period Table of the Elements.102. The method of wherein M is a Lanthanide element (numbers 58-71).103. The method of wherein M is an Actinide element (numbers 90-92).104. The method of wherein said solution processing route and said precursor lower the processing temperature by converting a metal amide to a metal or metal phosphide nanomaterial and said solution processing is less than 350 degrees C.105. The method of wherein said precursor converts to SnP.106. The method of wherein said precursor converts to SnP.107. The method of wherein changing solvent boiling temperature changes the particle size of said nanomaterial.108. The method of wherein said nanomaterials are used in batteries claim 95 , semiconductors claim 95 , magnets claim 95 , catalyst claim 95 , lasers claim 95 ...

ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME

An organic light-emitting device includes: a first electrode; a second electrode facing the first electrode; and an organic layer between the first electrode and the second electrode, the organic layer including an emission layer, wherein the organic layer includes a condensed cyclic compound represented by Formula 1. An organic light-emitting device including the organometallic compound according to the embodiments of the present disclosure may have high efficiency: 2. The organometallic compound of claim 1 , wherein M is copper (Cu).3. The organometallic compound of claim 1 , wherein Xis selected from P(R)(R) and N(R)(R); and Xis selected from P(R)(R) and N(R)(R).4. The organometallic compound of claim 1 , wherein CYand CYare each independently selectted from a benzene claim 1 , a naphthalene claim 1 , a fluorene claim 1 , a spiro-fluorene claim 1 , an indene claim 1 , a pyrrole claim 1 , a thiophene claim 1 , a furan claim 1 , an imidazole claim 1 , a pyrazole claim 1 , a thiazole claim 1 , an isothiazole claim 1 , an oxazole claim 1 , an isoxazole claim 1 , a triazole claim 1 , a pyridine claim 1 , a pyrazine claim 1 , a pyrimidine claim 1 , a pyridazine claim 1 , a quinoline claim 1 , an isoquinoline claim 1 , a benzoquinoline claim 1 , a quinoxaline claim 1 , a quinazoline claim 1 , a carbazole claim 1 , a benzoimidazole claim 1 , a benzofuran claim 1 , a benzothiophene claim 1 , an isobenzothiophene claim 1 , a benzoxazole claim 1 , an isobenzoxazole claim 1 , a triazole claim 1 , a tetrazole claim 1 , an oxadiazole claim 1 , a triazine claim 1 , a dibenzofuran claim 1 , a dibenzothiophene claim 1 , a benzofuropyridine claim 1 , and a benzothienopyridine.5. The organometallic compound of claim 1 , wherein CYand CYare each independently selected from a benzene claim 1 , a naphthalene claim 1 , an indene claim 1 , and a pyridine.6. The organometallic compound of claim 1 , wherein Z claim 1 , Z claim 1 , and Rto Rare each independently selected from:{'sub': 1', ...

Organic electroluminescent materials and devices

A compound having a structure according to formula (I) is disclosed. In formula (I), Cu is a monovalent copper atom; *C is a carbene carbon; X 1 and X 2 are selected from alkyl, cycloalkyl, alkoxy, amino, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, heteroalkynyl, arylalkyl, aryloxy, aryl, heteroalkyl, heteroaryl, and combinations thereof; X 1 and X 2 are independently bonded to *C by an atom selected from C, N, O, S, and P; X 1 and X 2 are optionally joined to form a ring; and Y is selected halide, alkyl, cycloalkyl, alkoxy, amino, phosphine, alkenyl, cycloalkenyl, heteroalkenyl, alkynyl, heteroalkynyl, arylalkyl, aryloxy, aryl, heteroalkyl, heteroaryl, and combinations thereof. A formulation containing compound having a structure according to formula (I), and a device with an organic layer comprising disposed between an anode and a cathode, that includes a compound having a structure according to formula (I) are also described.

Zinc Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand. 2. The method of claim 1 , further comprising (2) combining a reducing agent with the reaction product.4. The method of claim 3 , further comprising (2) combining an ionic activator with the reaction product.6. The method of claim 5 , further comprising (2) combining the reaction product with an a reducing agent.7. The method of claim 1 , where the reaction product comprises a Zn-ligand complex and a by-product of reaction of the Zn precursor and the ligand or of a side reaction therein.8. The method of claim 7 , further comprising removing all or a portion of the by-product.9. The method of claim 1 , further comprising using the product prepared by the method as a hydrosilylation catalyst.10. A composition comprising:{'claim-ref': {'@idref': 'CLM-00002', 'claim 2'}, '(A) a product prepared by the method of ; and'}(B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction; and(c) a polyorganohydrogensiloxane.11. A composition comprising:{'claim-ref': {'@idref': 'CLM-00004', 'claim 4'}, '(A) a product prepared by the method of ; and'}(B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction; and{'sup': 4', '4, 'sub': e', 'f, '(C) a silane of formula RSiH, where subscript e is 0, 1, 2, or 3; subscript f is 1, 2, 3, or 4 ...

PHOSPHINIC VANADIUM COMPLEX, CATALYTIC SYSTEM COMPRISING SAID PHOSPHINIC VANADIUM COMPLEX AND PROCESS FOR THE (CO) POLYMERIZATION OF CONJUGATED DIENES

Vanadium phosphinic complex having general formula (I) or (II): 16-. (canceled)8. The catalyst and at least one co-catalyst for (co) polymerization of conjugated diener according to claim 7 , wherein in said catalyst comprising said phosphinic vanadium complex having general formula (I) or (II):(i) X is an anion selected from halogen;{'sub': 1', '1', '20, 'R, identical or different among them, are a hydrogen atom; or are selected from a C-Calkyl group linear or branched; or are selected from an optionally substituted cycloalkyl group;'}n is an integer 0 or 1;{'sub': '2', 'R, identical or different among them, are selected from an optionally substituted aryl group; or'}(ii) X is an anion selected from chlorine, bromine, and iodine;{'sub': 1', '4', '20, 'R, identical or different among them, are a hydrogen atom; or are selected from C-Calkyl linear or branched; or are selected from an optionally substituted cycloalkyl group;'}n is an integer 2;{'sub': '2', 'R, identical or different among them, are selected from an optionally substituted aryl group; or'}{'sub': 3', '1', '20, 'R, identical or different among them, are selected from a C-Calkyl group, linear or branched; or are selected from an optionally substituted aryl group;'}{'sub': 5', '5', '4', '2, 'R4 represents a group —NRwherein Ris a hydrogen atom; or Ris a group —(CH)p- wherein p is 2.'}9. The catalyst and at least one co-catalyst for (co) polymerization of conjugated diener according to claim 7 , wherein in said catalyst comprising said phosphinic vanadium complex having general formula (I) or (II):(i) X is an anion selected from chlorine, bromine, and iodine;{'sub': '1', 'R, identical or different among them, are a hydrogen atom; or are selected from methyl, ethyl, iso-propyl, and tert-butyl; or are selected from cyclopentyl and cyclohexyl;'}n is an integer 0;R2, identical or different among them, are phenyl; or(ii) X is an anion selected from chlorine, bromine, and iodine;{'sub': '1', 'R, identical or ...

PINCER-TYPE LIGAND HAVING ACRIDANE STRUCTURE AND METAL COMPLEX USING THE SAME

Disclosed are a pincer-type ligand having a structurally rigid acridane structure and a metal complex consisting of the pincer-type ligand and a metal bound to each other, and exhibiting high reactivity and stability during a variety of bonding activation reactions. T-shaped complexes can be prepared from PNP(4,5-bis(diisopropylphosphino)-2,7,9,9-tetramethyl-9H-acridin-10-ide), which is a pincer-type PNP ligand having an acridane structure, and metal complexes, which can be structurally rigid and thus exhibit excellent reactivity and stability based on minimized structural change thereof, can be prepared by introducing an acridane structure into the backbone thereof. The PNP ligand is structurally stable and has novel chemical properties, as compared to conventional similar ligands, and thus can be utilized in a wide range of catalytic reactions and material chemistry. 3. The metal complex of claim 1 , wherein the metal complex is represented by (PNP)MX claim 1 ,wherein n=0, 1, 2 or 3, andX is ABC, wherein A, B and C are each independently represented by a monodentate ligand or bidentate ligand. This is a divisional under 35 USC § 120 of U.S. patent application Ser. No. 16/260,086 filed Jan. 28, 2019 for “PINCER-TYPE LIGAND HAVING ACRIDANE STRUCTURE AND METAL COMPLEX USING THE SAME”, which in turn claims the priority under 35 USC § 119 of Korean Patent Application 10-2018-0011432 filed Jan. 30, 2018. The disclosures of U.S. patent application Ser. No. 16/260,086 and Korean Patent Application 10-2018-0011432 are hereby incorporated herein by reference, in their respective entireties, for all purposes.The present invention relates a pincer-type ligand having an acridane structure and a metal complex using the same and more particularly, to a pincer-type ligand having a structurally rigid acridane structure and a metal complex consisting of the pincer-type ligand and a metal bound to each other and exhibiting high reactivity and stability during a variety of bonding ...

Iridium Containing Hydrosilylation Catalysts and Compositions Containing the Catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable, of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES

The invention relates to tetra-nuclear neutral copper (I) complexes of Formula (A) that have a cubane-like structure, wherein said complexes comprise phosphine ligands which bear one or more aldehyde or ester groups. Furthermore, the present invention refers to methods for generating such copper (I) complexes of Formula (A) and to uses thereof. Each L is independently from each other a ligand that has a structure of Formula (A1): P(Ar)(CHR2-CHR1-CO—Y-Rx). 2. The copper (I) complex of claim 1 , wherein each X is iodine.3. The copper (I) complex of claim 1 , wherein each ligand L is a monovalent ligand of the same kind.4. The copper (I) complex of claim 1 , wherein each L is independently from each other a diarylphosphine residue of Formula (A2):{'br': None, 'sub': m', 'n, 'P(Ar)(CHR2-CHR1-CO—Y—R13)\u2003\u2003(A2),'} [{'sup': a', 'b', 'b', 'b', 'b', 'b', 'b', 'b', 'c', 'b', 'c', 'b', 'c', 'b', 'c', 'b, 'R13 is —R—R, —R—CO—O—R, —R—O—CO—R, —R—O—R, —R—CO—NH—R, —R—NH—CO—R, —R—NH—R, —R—CO—R, di- or polyethylene glycol, di- or polypropylene glycol, a polymeric moiety, or a solid support; and'}, {'sup': 'c', 'sub': 1', '20', '2', '20', '2', '20', '1', '20', '2', '20', '2', '20', '2', '20', '2', '20, 'Rat each occurrence independently from another is an unsubstituted or substituted C-C-(hetero)alkylene residue, an unsubstituted or substituted C-C-(hetero)alkenylene residue, an unsubstituted or substituted C-C-(hetero)alkinylene residue, an unsubstituted or substituted C-C-(hetero)cycloalkylene residue, an unsubstituted or substituted C-C-(hetero)cycloalkenylene residue, an unsubstituted or substituted C-C-(hetero)cycloalkinylene residue, an unsubstituted or substituted C-C-(hetero)arylene residue, or an unsubstituted or substituted C-C-alk(hetero)arylene residue,'}, {'sup': a', 'b, 'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'P, Ar, R1, R2, Y, R, R, m and n are defined as in , and'}], 'whereinwherein the phosphorous is bound to Cu.6. The copper (I) complex of claim 1 , ...

TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF

In one aspect, phosphine compounds comprising three adamantyl moieties (PAd) and associated synthetic routes are described herein. Each adamantyl moiety may be the same or different. For example, each adamantyl moiety (Ad) attached to the phosphorus atom can be independently selected from the group consisting of adamantane, diamantane, triamantane and derivatives thereof. Transition metal complexes comprising PAdligands are also provided for catalytic synthesis including catalytic cross-coupling reactions. 1. A method of synthesizing a tri-(adamantyl)phosphine compound , PAd , comprising:{'sub': 2', '2', 'N', '3, 'providing a reaction mixture including di-(adamantyl)phosphine (PAd) and a substituted adamantyl moiety and reacting the PAdand substituted adamantyl moiety via an S1 pathway to provide the PAd.'}2. The method of claim 1 , wherein adamantyl moieties (Ad) of the PAdare independently selected from the group consisting of adamantane claim 1 , diamantane claim 1 , triamantane and derivatives thereof.3. The method of claim 1 , wherein the substituted adamantyl moiety comprises a leaving group.4. The method of claim 3 , wherein the leaving group is selected from the group consisting of acetate claim 3 , triflate claim 3 , tosylate and hydroxyl.5. The method of claim 1 , wherein yield of the PAdis greater than 50 percent.6. The method of claim 1 , wherein yield of the PAdis greater than 60 percent.7. The method of claim 1 , wherein synthesizing the tri-(adamantyl)phosphine is performed at room temperature.8. A method of synthesizing a tri-(adamantyl)phosphine compound claim 1 , PAd claim 1 , comprising:{'sub': 2', 'N', '3, 'providing a reaction mixture including di-(adamantyl)phosphide and a substituted adamantyl moiety and reacting the PAdand substituted adamantyl moiety via an S1 pathway to provide the PAd.'}9. The method of claim 8 , wherein adamantyl moieties (Ad) of the di-(adamantyl)phosphide are independently selected from the group consisting of ...

METALATED LIGAND, CATALYST COMPOSITION, AND USE THEREOF IN THE OLIGOMERIZATION OF ETHYLENE

A process for oligomerization of ethylene, comprising subjecting a catalyst composition to a gas phase of ethylene and conducting an oligomerization, wherein the catalyst composition comprises (a) a chromium compound, (b) a metalated ligand, and (c) an activator or cocatalyst; and catalyst composition as well as a metalated ligand. 2. The catalyst composition of claim 1 , further comprising an ammonium or phosphonium salt of the formula [HE]X claim 1 , [HER]X claim 1 , [HER]X claim 1 , [HER]X claim 1 , or [ER]X wherein E is N or P claim 1 , X is Cl claim 1 , Br or I claim 1 , and each R is independently C-C-alkyl claim 1 , C-C-cycloalkyl claim 1 , C-C-acyl claim 1 , C-C-aryl claim 1 , C-C-alkenyl claim 1 , or C-C-alkynyl.3. The process according to claim 1 , wherein the oligomerization is carried out a pressure of 1 to 200 bar.4. The process according to claim 1 , wherein the oligomerization is carried out at a temperature of from 10 to 200° C.5. The process according to claim 1 , wherein the mean residence time is from 20 minutes to 20 hours.7. The catalyst composition according to claim 6 , wherein the chromium compound is selected from organic or inorganic salts claim 6 , coordination complexes claim 6 , organometallic complexes of Cr(II) or Cr(III) claim 6 , or a combination comprising at least one of the foregoing.8. The catalyst composition according to claim 6 , wherein the chromium compound is CrCl(THF) claim 6 , Cr(III)acetyl acetonate claim 6 , Cr(III)octanoate claim 6 , chromium hexacarbonyl claim 6 , Cr(III)-2-ethyl-hexanoate and (benzene)tricarbonyl-chromium claim 6 , or a combination comprising at least one of the foregoing.9. The catalyst composition according to claim 6 , wherein the activator or co-catalyst is selected from trimethyl aluminum claim 6 , triethyl aluminum claim 6 , triisopropyl aluminum claim 6 , triisobutyl aluminum claim 6 , ethyl aluminum sesquichloride claim 6 , diethyl aluminum chloride claim 6 , ethyl aluminum dichloride claim 6 ...

Molybdenum Containing Hydrosilylation Reaction Catalysts and Compositions Containing the Catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition ′ capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Process for synthesis of ezetimibe and intermediates used in said process

A process for the production of ezetimibe and intermediates used in said process are disclosed. A kind of Morita-Baylis-Hillman adduct can be altered to chiral carboxylic acid derivatives of β-arylamino α-methylene with high activity and selectivity by means of ally lamination reaction, and the above carboxylic acid derivatives of β-arylamino α-methylene can be altered to the chiral intermediates of ezetimibe by means of simple conversion and further synthesized into the chiral drug ezetimibe. The synthesis route introduces chirality through the use of a chiral catalysis method, thereby avoiding the use of the chiral auxiliary oxazolidinone; and the route is economical and eco-friendly.

DISTORTED GOLD (I)-PHOSPHINE COMPLEXES AND AND METHODS FOR USE AS ANTIFUNGAL AGENTS

The presently-disclosed subject matter describes distorted gold (I) phosphine compounds. The presently-disclosed subject matter also describes a method for killing fungus comprising contacting fungus with distorted gold (I) phosphine compounds. The presently-disclosed subject matter further describes a method of preventing or disrupting a biofilm on a surface comprising contacting a surface with distorted gold (I) phosphine compounds. 2. A compound of claim 1 , wherein Rand Rare identical.3. A compound of claim 1 , wherein Rand Rare phenyl.4. A compound of claim 1 , wherein Rand Rcyclize to form a 5-membered substituted cycloalkyl.8. A method for killing fungus comprising: contacting the fungus with an effective amount of a compound of .9Candida.. The method of claim 8 , wherein the fungus is of the genus10Cryptococcus.. The method of claim 8 , wherein the fungus is of the genus11Aspergillus.. The method of claim 8 , wherein the fungus is of the genus12Fusarium. The method of claim 8 , wherein the fungus is of the genus13. The method of wherein the effective amount is between about 0.12 μg/mL to about 31.3 μg/mL.14. The method of claim 8 , wherein the fungus is in a subject.15. The method of wherein the subject is a mammal.16. The method of claim 15 , wherein the effective amount is an amount less than about 8 mg/kg.17. A method of preventing or disrupting a fungal biofilm comprising: contacting a surface with an effective amount of a compound of claim 1 , wherein the surface is at risk of forming a biofilm or has a pre-formed biofilm.19. The method of claim 17 , wherein the effective amount is between about 0.12 μg/mL to about 31.3 μg/mL.20. The method of claim 17 , wherein the contact occurs for about 3 hours. This application claims priority from U.S. Provisional Patent Application No. 62/946,349 filed on Dec. 10, 2020 the entire disclosure of which is incorporated herein by this reference.The presently-disclosed subject matter generally relates to antifungals ...

GOLD(I) COMPLEXES WITH ANTICANCER PROPERTIES AND METHODS OF USE THEREOF

Monomeric and dimeric gold(I) complexes as anticancer agents. The gold(I) complexes are coordinated to mixed ligands: one phosphine-based ligand that may be monodentate or bidentate and at least one dithiocarbamate-based ligand that is monodentate. Pharmaceutical compositions incorporating the gold(I) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis are also provided. 25-: (canceled)6: The composition of claim 1 , wherein the composition is in a solid claim 1 , semi-solid claim 1 , or liquid dosage form.7: The composition of claim 1 , wherein the composition is formulated for one or more modes of administration selected from the group consisting of oral administration claim 1 , systemic administration claim 1 , parenteral administration claim 1 , inhalation spray claim 1 , infusion claim 1 , rectal administration claim 1 , topical administration claim 1 , intravesical administration claim 1 , intradermal administration claim 1 , transdermal administration claim 1 , subcutaneous administration claim 1 , intramuscular administration claim 1 , intralesional administration claim 1 , intracranial administration claim 1 , intrapulmonal administration claim 1 , intracardial administration claim 1 , infrasternal administration and sublingual administration.8: A method for inhibiting proliferation of cancer cells claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'contacting the cancer cells with the composition of .'}9: The method of claim 8 , wherein the cancer cells are human cells.10: The method of claim 8 , wherein the cancer cells are at least one selected from the group consisting of lung cancer cells claim 8 , colorectal cancer cells and cervical cancer cells.11: The method of claim 8 , wherein the gold(I) complex concentration is 5-50 μM.12: The method of claim 8 , wherein the gold(I) complex exhibits an ICof 1-150 μM for inhibiting the proliferation ...

PHOSPHINIC VANADIUM COMPLEX, CATALYTIC SYSTEM COMPRISING SAID PHOSPHINIC VANADIUM COMPLEX AND PROCESS FOR THE (CO) POLYMERIZATION OF CONJUGATED DIENES

Vanadium phosphinic complex having general formula (I) or (II): 16-. (canceled)7. A catalytic system for the (co) polymerization of conjugated dienes comprising: [{'br': None, 'sub': 3', '1', 'n', '2', '3-n', '2, 'V(X)[P(R)(R)]\u2003\u2003(I)'}, {'br': None, 'sub': 3', '3', '2', '4', '3', '2, 'V(X)[(R)P(R)P(R)]\u2003\u2003(II)'}], '(a) at least one phosphinic vanadium complex having the general formula (I) or (II) X represents a halogen anion; or is selected from the following groups: thiocyanate, isocyanate, sulfate, acid sulfate, phosphate, acid phosphate, carboxylate and dicarboxylate;', {'sub': 1', '2', '2', '1', '20, 'R, identical or different among them, represent a hydrogen atom, or an allyl group (CH═CH—CH—); or are selected from a C-Calkyl group, linear or branched, and an optionally halogenated, optionally substituted cycloalkyl group;'}, 'n is an integer ranging from 0 to 3;', {'sub': '2', 'R, identical or different among them, represent an optionally substituted aryl group;'}, {'sub': 3', '2', '2', '1', '20, 'R, identical or different among them, represent a hydrogen atom, or an allyl group (CH═CH—CH—); or are selected from a C-Calkyl group, linear or branched, an optionally halogenated, optionally substituted cycloalkyl group, and an optionally substituted aryl group;'}, {'sub': 4', '5', '5', '1', '20', '4, 'Rrepresents a group —NRwherein Rrepresents a hydrogen atom, or is a C-Calkyl group, linear or branched; or Rrepresents an alkylene group'}, {'sub': '2', '—(CH) p- wherein p represents an integer ranging from 1 to 5;'}], 'wherein{'sub': 1', '2, 'provided that in the general formula (I), in case n is equal to 1 and Ris methyl, Ris different from phenyl;'} [{'sub': '1', 'claim-text': [{'br': None, 'sub': 6', '7', '8, 'Al(R)(R)(R)\u2003\u2003(III)'}, {'sub': 6', '1', '20', '7', '8', '1', '20, 'wherein Rrepresents a hydrogen atom, or a fluorine atom, or is selected from a C-Calkyl group, linear or branched, a cycloalkyl group, an aryl group, an alkylaryl ...

TETRA-NUCLEAR NEUTRAL COPPER (I) COMPLEXES WITH DIARYLPHOSPHINE LIGANDS

The present invention relates to tetra-nuclear neutral copper (I) complexes that have a cubane-like structure, wherein said complexes further comprise diarylphosphine ligands which are bonded via phosphorus atoms. Furthermore, the present invention refers to methods for generating such copper (I) complex and to uses thereof. The present invention further relates to cubane-like conjugates that comprise moiety of the copper (I) complexes of the invention. Formula (A), each L is independently from each other an optionally substituted diary lphosphine residue of Formula (A1): PHSr(A1). 2. The copper (I) complex of claim 1 , wherein each X is iodine.3. The copper (I) complex of claim 1 , wherein each Ar is independently from each other a phenyl residue Ph that is unsubstituted or substituted by one or more substituents each independently from each other selected from the group consisting of a linear or branched claim 1 , unsubstituted or substituted C-C-alkyl residue claim 1 , a linear or branched claim 1 , unsubstituted or substituted C-C-alkoxy residue and halogen claim 1 , wherein each substituent may optionally be or contribute to a linker that interconnects two ligands L with another.6. The copper (I) complex of claim 1 , wherein each L is a monovalent ligand of the same kind.7. The copper (I) complex of claim 1 , wherein two L are interconnected with another claim 1 , thereby forming a bivalent ligand.9. A method for generating a copper (I) complex of claim 1 , said method comprising the following steps: (a) copper (I) halide,', {'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, '(b) an electronically neutral substituted ligand L as defined in , and'}, '(c) a solvent in which components (a) and (b) are dissolved;, 'providing, in an inert atmosphere(ii) incubating the composition of step (i) at conditions allowing the formation of the copper (I) complex; and(iii) optionally removing the solvent and obtaining a solid residue; and(iv) optionally mixing the composition ...

Phosphine transition metal complex, method for producing same, and anticancer agent

The phosphine transition metal complex of the present invention is represented by formula (1).Preferably, R1 and R6 are identical groups, R2 and R7 are identical groups, R3 and R8 are identical groups, R4 and R9 are identical groups, R5 and R10 are identical groups, and n and y are identical numbers. The phosphine transition metal complex is suitably obtained by reacting a phosphine derivative represented by formula (2) and a phosphine derivative represented by formula (3) with a salt of a transition metal of gold, copper or silver.See the description for the meanings of the symbols in each formula.

COPPER (I) PYRAZOLATE DIMERS FOR ELECTROLUMINESCENT DEVICES

The invention provides compositions comprising copper(I) pyrazolate dimer compounds for use in OLEDs applications. The inventive compositions can be used to generate visible light colors or a color blend in electronic devices. 2. The composition of claim 1 , wherein E1 claim 1 , E2 claim 1 , E3 and E4 are each P.3. The composition of claim 1 , wherein R1 claim 1 , R2 claim 1 , R3 claim 1 , R4 claim 1 , R5 claim 1 , R6 claim 1 , R7 and R8 are each claim 1 , independently claim 1 , a substituted or unsubstituted aryl claim 1 , further an unsubstituted aryl claim 1 , and further each is phenyl.4. The composition of claim 1 , wherein at least two of X1 claim 1 , X2 and X3 are C—H; and at least two of X4 claim 1 , X5 and X6 are C—H.5. The composition of claim 1 , wherein X1 and X3 are each C—H; and X4 and X6 are each C—H.6. (canceled)7. The composition of claim 1 , wherein L1 and L2 are each claim 1 , independently claim 1 , a substituted or unsubstituted alkylene claim 1 , a substituted or unsubstituted arylene claim 1 , or a substituted or unsubstituted heteroarylene.8. The composition of claim 1 , wherein L1=L2.10. The composition of claim 1 , wherein L1 and L2 each claim 1 , independently claim 1 , comprise at least one phenylene group.12. The composition of claim 1 , wherein the compound of Structure 1 has a molecular weight from 950 to 10 claim 1 ,000 g/mole.13. (canceled)14. (canceled)15. A film formed from the composition of .16. The film of claim 15 , wherein the film is formed from casting from a solution.17. The film of claim 15 , wherein the film is formed by deposition from an evaporation process or a sublimation process in a vacuum.18. An electronic device comprising at least one component formed the composition of .19. An electronic device comprising at least one component formed from the film of .20. The electronic devise of claim 18 , wherein the compound of Structure 1 generates visible light colors claim 18 , and wherein the visible light colors are ...

Pincer-type ligand having acridane structure and metal complex using the same

Disclosed are a pincer-type ligand having a structurally rigid acridane structure and a metal complex consisting of the pincer-type ligand and a metal bound to each other, and exhibiting high reactivity and stability during a variety of bonding activation reactions. T-shaped complexes can be prepared from acri PNP(4,5-bis(diisopropylphosphino)-2,7,9,9-tetramethyl-9H-acrid in-10-ide), which is a pincer-type PNP ligand having an acridane structure, and metal complexes, which can be structurally rigid and thus exhibit excellent reactivity and stability based on minimized structural change thereof, can be prepared by introducing an acridane structure into the backbone thereof. The PNP ligand is structurally stable and has novel chemical properties, as compared to conventional similar ligands, and thus can be utilized in a wide range of catalytic reactions and material chemistry.

PLATINUM COMPLEXES HAVING BENZYL-BASED DIPHOSPHINE LIGANDS FOR THE CATALYSIS OF THE ALKOXYCARBONYLATION OF ETHYLENICALLY UNSATURATED COMPOUNDS

Platinum complexes having benzyl-based diphosphine ligands for the catalysis of the alkoxycarbonylation of ethylenically unsaturated compounds. 2. Complex according to claim 1 ,{'sup': 1', '2', '3', '4, 'sub': 5', '20, 'wherein at least two of the R, R, R, Rradicals are a -(C-C)-heteroaryl radical having at least six ring atoms.'}3. Complex according to claim 1 ,{'sup': 1', '3, 'sub': 6', '20, 'wherein the Rand Rradicals are each a -(C-C)-heteroaryl radical having at least six ring atoms.'}4. Complex according to claim 1 ,{'sup': 1', '3, 'wherein the Rand Rradicals are each 2-pyridyl.'}5. Complex according to claim 1 ,{'sup': 2', '4, 'sub': 1', '12, 'wherein Rand Rare -(C-C)-alkyl.'}6. Complex according to claim 1 ,{'sup': 2', '4, 'wherein Rand Rare Cert-butyl.'}9. Process according to claim 8 ,wherein the ethylenically unsaturated compound is selected from: ethene, propene, 1-butene, cis- and/or trans-2-butene, isobutene, 1,3-butadiene, 1-pentene, cis- and/or trans-2-pentene, 2-methyl-1-butene, 3-methyl-1-butene, 2-methyl-2-butene, hexene, tetramethylethylene, heptene, 1-octene, 2-octene, di-n-butene, or mixtures thereof.10. Process according to claim 8 ,wherein the alcohol in process step c) is selected from: methanol, ethanol, 1-propanol, 1-butanol, 1-pentanol, 1-hexanol, 2-propanol, tert-butanol, 3-pentanol, cyclohexanol, phenol.11. Process according to any of to claim 8 ,wherein the alcohol in process step c) is methanol.12. Process according to claim 8 ,{'sub': 2', '2', '2', '2', '2', '2', '3', '2', '2', '2, 'wherein the substance comprising Pt is selected from: platinum dichloride (PtCl), platinum(II) acetylacetonate [Pt(acac)], platinum(II) acetate [Pt(OAc)], dichloro(1,5-cyclooctadiene)platinum(II) [Pt(cod)Cl], bis(dibenzylideneacetone)platinum [Pt(dba)], bis(acetonitrile)dichloroplatinum(II) [Pt(CHCN)Cl], (cinnamyl)platinum dichloride [Pt(cinnamyl)Cl].'}13. Process according to claim 8 ,{'sub': 2', '2', '2, 'wherein the substance comprising Pt is selected ...

Gold(i) complexes with t-butyl phosphine and dialkyl dithiocarbamate ligands

Gold(I) complexes of formulae [Au{P(t-Bu) 3 }(S 2 CN(CH 3 ) 2 )] (1), and [Au{P(t-Bu) 3 }(S 2 CN(C 2 H 5 ) 2 )] (2) have been prepared by the reaction of equimolar amounts of [Au{P(t-Bu) 3 }(Cl)] with sodium dimethyldithiocarbamate monohydrate, and sodium diethyldithiocarbamate trihydrate respectively. Both complexes (1) and (2) are iso-structural having linear geometry. These gold(I) dithiocarbamate complexes show in vitro cytotoxic activities against A549 (human lung carcinoma), HeLa (human cervical cancer) and MCF7 (human breast cancer) cell lines.

ORGANIC MAGNESIUM PHOSPHIDE AND MANUFACTURING METHOD THEREOF, ORGANIC MAGNESIUM PHOSPHIDE COMPLEX AND MANUFACTURING METHOD THEREOF, AND MANUFACTURING METHOD OF ORGANIC PHOSPHORUS COMPOUND USING SAID PHOSPHIDE

An organic magnesium phosphide expressed by Formula (1) below and an organic magnesium phosphide complex expressed by Formula (9) below are provided, and a manufacturing method of organic phosphorus compound is characterized in that the above compounds used as a reagent is reacted with an electrophile: 2. The organic magnesium phosphide according to claim 1 , wherein Rand Rare tertiary alkyl groups.4. The organic magnesium phosphide according to claim 1 , wherein Rand Rare alicyclic groups.6. (canceled)7. (canceled)9. The organic magnesium phosphide complex according to claim 8 , wherein Rand Rare tertiary alkyl groups.11. The organic magnesium phosphide complex according to claim 8 , wherein Rand Rare alicyclic groups.13. (canceled)14. (canceled) The present invention relates to: a new organic magnesium phosphide characterized by phosphorus-magnesium bond and a manufacturing method thereof; a new organic magnesium phosphide complex and a manufacturing method thereof; and a new manufacturing method of organic phosphorus compound using such organic magnesium phosphide or organic magnesium phosphide complex.Organic phosphorus compounds are used in wide-ranging applications such as ligands in transition metal catalysts and hardening accelerators for epoxy resins. For example, an organic phosphorus compound expressed as 1,2-bis (di-t-butyl phosphinomethyl) benzene is a catalyst ligand that exhibits highly desirable activity in the carbonylation reaction of olefinic unsaturated compounds. Also, an organic phosphorus compound expressed as 2,2′-bis diphenyl phosphanylmethyl-1,1′-biphenyl and derivatives thereof are catalyst ligands that exhibit highly desirable activity and selectivity in the hydroformylation reaction.Among the key methods for manufacturing such organic phosphorus compounds, methods involving the reaction between a phosphinous chloride and a lithium reagent or Grignard reagent are well known (Patent Literature 1). Also, manufacturing methods using the ...

TWO-COMPONENT ANTI-CANCER COMPOSITION

Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamte ligands are connected by Au(I)-Au(I) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer. 2: The composition of claim 1 , wherein the anion is a halide ion claim 1 , a trifluoromethanesulfonate ion claim 1 , a hexafluorophosphate ion claim 1 , a tetrafluoroborate ion claim 1 , or a perchlorate ion.3: The composition of formula (I) of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , and Rare a hydrogen claim 1 , and X is Cl.4: The composition of further comprising a pharmaceutically acceptable carrier and/or excipient.5: The composition of claim 4 , which comprises 0.01-100 μM of the gold(I) complex relative to the total volume of the composition.6: The composition of claim 4 , wherein the pharmaceutically acceptable carrier and/or excipient is at least one selected from the group consisting of an organic solvent claim 4 , an inorganic salt claim 4 , a surfactant claim 4 , and a polymer.720-. (canceled) This application claims the benefit of priority of U.S. Provisional Application No. 62/486,169 filed Apr. 17, 2017, the entire contents of which are herein incorporated by reference.This project was funded by the National Plan for Science and Innovation (MARIFAH)-King Abdulaziz City for Science and Technology (KACST) through the Science and Technology Unit at King Fahd University of Petroleum and Minerals (KFUPM) of Saudi Arabia, award No. 14-MED64-4.Aspects of this technology are described in an article “Synthesis, ...

METHOD OF TREATING CANCER WITH A TWO-COMPONENT ANTI-CANCER COMPOSITION

Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamte ligands are connected by Au(I)—Au(I) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer. 16-. (canceled)8. The method of claim 7 , wherein the cancer is resistant to cisplatin.9. (canceled)10. The method of claim 7 , wherein 1-300 mg/kg of gold(I) complex of formula (I) is administered per body weight of the subject.1120-. (canceled) This application claims the benefit of priority of U.S. Provisional Application No. 62/486,169 filed Apr. 17, 2017, the entire contents of which are herein incorporated by reference.This project was funded by the National Plan for Science and Innovation (MARIFAH)-King Abdulaziz City for Science and Technology (KACST) through the Science and Technology Unit at King Fahd University of Petroleum and Minerals (KFUPM) of Saudi Arabia, award No. 14-MED64-4.Aspects of this technology are described in an article “Synthesis, Characterization and in vitro Cytotoxicity of Gold(I) Complexes of 2-(Diphenylphosphanyl)ethylamine and Dithiocarbamates” published in Journal of Inorganic and General Chemistry, 2016, 642, (24), 1454-1459, on Nov. 3, 2016, which is incorporated herein by reference in its entirety.The present invention relates to therapeutic gold(I) complexes, a pharmaceutical composition thereof, and a method of treating cancer. The present invention further relates to therapeutic gold(I) dithiocarbamate polymers, a pharmaceutical composition thereof, and a method of treating cancer.The “background” description provided herein is for the purpose of generally presenting the context of the ...

PHOSPHINIC VANADIUM COMPLEX, CATALYTIC SYSTEM COMPRISING SAID PHOSPHINIC VANADIUM COMPLEX AND PROCESS FOR THE (CO) POLYMERIZATION OF CONJUGATED DIENES

Vanadium phosphinic complex having general formula (I) or (II): V(X)M3P̂WFys-nMO V(X)3[(R3)2P(R4)P(R3)2] (ID wherein: X represents an anion selected from halogens such as, for example, chlorine, bromine, iodine, preferably chlorine; or is selected from the following groups: thiocyanate, isocyanate, sulfate, acid sulfate, phosphate, acid phosphate, carboxylate, dicarboxylate; Ri, identical or different among them, represent a hydrogen atom, or an allyl group (CH2=CH—CH2-); or are selected from alkyl groups CrC2o, preferably CrĈ, linear or branched, optionally halogenated, optionally substituted cycloalkyl groups; —n is an integer ranging from 0 to 3; R2, identical or different among them, are selected from optionally substituted aryl groups; R3, identical or different among them, represent a hydrogen atom, or an allyl group (CH2=CH—CH2-); or are selected from alkyl groups C1-C2o, preferably CrĈ, linear or branched, optionally halogenated, optionally substituted cycloalkyl groups, optionally substituted aryl groups; R4 represents a group —NR5 wherein R5 represents a hydrogen atom, or is selected from C1-C20 alkyl groups, preferably CrC15, linear or branched; or R4 represents an alkylene group —(CH2) p- wherein p represents an integer ranging from 1 to 5; provided that in the general formula (I), in case n is equal to 1 and Ri is methyl, R2 is different from phenyl. Said phosphinic vanadium complex having general formula (I) or (II) can be advantageously used in a catalytic system for the (co)polymerization of conjugated dienes. 2. Vanadium phosphinic complex having general formula (I) or (II) according to claim 1 , wherein:X is an anion selected from halogen;{'sub': 1', '1', '20, 'R, identical or different among them, are a hydrogen atom; or are selected from C-Calkyl groups, linear or branched; or are selected from optionally substituted cycloalkyl groups;'}n is an integer ranging from 0 to 3;{'sub': '2', 'R, identical or different among them, are selected from ...

First-Row Transition Metal Hydrogenation and Hydrosilylation Catalysts

Transition metal compounds, and specifically transition metal compounds having a tetradentate and/or pentadentate supporting ligand are described, together with methods for the preparation thereof and the use of such compounds as hydrogenation and/or hydrosilylation catalysts. 4. The metal complex of claim 1 , wherein:M is Mn, Fe, Co, or Ni; and{'sub': 2', '2, 'each X is independently selected from PR, NR, and any other donor group.'}5. The metal complex of claim 3 , wherein Z is hydride.6. A catalytic composition comprising the metal complex of .7. A method for reducing one or more organic substrates comprising contacting a composition comprising one or more organic substrates with a catalytic composition comprising a metal complex according to in the presence of a reductant claim 1 , whereby the one or more organic substrates are reduced.8. The method of claim 8 , wherein the reductant is a silane claim 8 , a substituted silane claim 8 , an alkoxysilane claim 8 , hydrogen claim 8 , a substituted borane claim 8 , a substituted alane claim 8 , or a mixture thereof.9. The method of claim 7 , wherein the one or more organic substrates contain a ketone claim 7 , an ester claim 7 , or mixtures thereof.10. The method of claim 9 , wherein the one or more organic substrates include an unsaturated organic compound.11. The method of claim 10 , wherein the unsaturated organic compound is an olefin or an alkyne.12. A method of facilitating a hydrosilylation reaction claim 1 , comprising reacting a compound comprising an Si—H bond with an unsaturated organic compound in the presence of one or more of the metal complexes of .13. The method of claim 12 , whereby the Si and H atoms in the Si—H bond are added across an unsaturated bond in the unsaturated organic compound to form an organosilicon compound.14. A method of facilitating a hydrogenation reaction claim 1 , comprising reacting Hwith an unsaturated organic compound in the presence of one or more of the metal complexes of . ...

Metal complex and method for producing the same, catalyst component for olefin polymerization and catalyst for olefin polymerization containing the metal complex, and methods for producing ?-olefin polymer and copolymer using the catalyst for olefin polymerization

Provided are a novel catalyst component for producing an α-olefin (co)polymer, and a production method using the same. A metal complex is obtainable by contacting a compound represented by the general formula [I] or [II] with a transition metal compound containing a transition metal belonging to 9th to 11th group: wherein R 1 , R 2 , R 3 and R 4 represent (i) hydrogen, (ii) a halogen, (iii) a linear alkyl or the like, or (iv) OR 9 or the like; R 5 and R 6 represent a linear alkyl group or the like; any one of R 1 -R 6 may have a heteroatom or a heteroatom containing group; E 1 represents phosphorus, arsenic or antimony; X 1 represents oxygen or sulfur; Z represents hydrogen or a leaving group.

COMPOSITION CONTAINING A GOLD (I) COMPLEX AND CANCER CELLS

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer. 2. The gold(I) complex of claim 1 , wherein Rand Rare the same claim 1 , and R claim 1 , R claim 1 , and Rare the same optionally substituted C-Calkyl group.3. The gold(I) complex of claim 2 , wherein Rand Rare methyls claim 2 , and R claim 2 , R claim 2 , and Rare selected from the group consisting of methyl claim 2 , ethyl and isopropyl.4. The gold(I) complex of claim 2 , wherein Rand Rare ethyls claim 2 , and R claim 2 , R claim 2 , and Rare methyls.520-. (canceled)21. The gold(I) complex of claim 1 , wherein Rand Rare methyls and R claim 1 , R claim 1 , and Rare ethyls.22. The gold(I) complex of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , and Rare each a methyl group. This application claims the priority of the filing date of the U.S. Provisional Patent Application No. 62/326,389 filed Apr. 22, 2016, the disclosure of which is hereby incorporated herein by reference in its entirety.This project was funded by the National Plan for Science and Innovation (MARIFAH)—King Abdulaziz City for Science and Technology (KACST) through the Science and Technology Unit at King Fahd University of Petroleum and Minerals (KFUPM) of Saudi Arabia, award No. 14-MED64-04.The present disclosure relates to therapeutic gold(I) complexes, a pharmaceutical composition thereof, and a method of treating cancer.The “background” description provided herein is for the purpose of generally presenting the context of the disclosure. Work of the presently named inventors, to the extent it is described in this background section, as well as aspects of the description which may not otherwise qualify as prior art at the time of filing, are neither ...

GOLD COMPLEXES OF ALKYLATED PHOSPHINES

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer. 2. The gold(I) complex of claim 1 , wherein Rand Rare the same unsubstituted alkyl group claim 1 , and R claim 1 , R claim 1 , and Rare the same optionally substituted C-Calkyl group.3. (canceled)4. The gold(I) complex of claim 2 , wherein Rand Rare ethyls claim 2 , and R claim 2 , R claim 2 , and Rare methyls.5. (canceled)6. A composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'the gold(I) complex of ; and'}a pharmaceutically acceptable carrier or excipient.7. The composition of claim 6 , which comprises 0.01-50 μM of the gold(I) complex relative to the total composition.8. (canceled)9. The composition of claim 6 , further comprising:at least one chemotherapeutic agent selected from the group consisting of aflibercept, asparaginase, bleomycin, busulfan, carmustine, chlorambucil, cladribine, cyclophosphamide, cytarabine, dacarbazine, daunorubicin, doxorubicin, etoposide, fludarabine, gemcitabine, hydroxyurea, idarubicin, ifosfamide, irinotecan, lomustine, mechlorethamine, melphalan, mercaptopurine, methotrexate, mitomycin, mitoxantrone, pentostatin, procarbazine, topotecan, vinblastine, vincristine, retinoic acid, oxaliplatin, carboplatin, 5-fluorouracil, teniposide, amasacrine, docetaxel, paclitaxel, vinorelbine, bortezomib, clofarabine, capecitabine, actinomycin D, epirubicin, vindesine, methotrexate, 6-thioguanine, tipifarnib, imatinib, erlotinib, sorafenib, sunitinib, dasatinib, nilotinib, lapatinib, gefitinib, temsirolimus, everolimus, rapamycin, bosutinib, pzopanib, axitinib, neratinib, vatalanib, pazopanib, midostaurin, enzastaurin, trastuzumab, cetuximab, panitumumab, rituximab, bevacizumab, mapatumumab, ...

NOVEL COMPLEX AND USE OF SAME

A novel complex capable of fixing dinitrogen and use thereof are provided. A complex represented by formula (1A) or (1B) or a cationic or anionic complex from the complex: 3. The complex as set forth in claim 2 , wherein claim 2 , in formula (2) claim 2 , all of R1 to R5 are methyl groups claim 2 , or four of R1 to R5 are methyl groups and the other one of R1 to R5 is a trialkylsilyl group.4. The complex as set forth in claim 1 , wherein each of M1 to M4 (M1 to M3 in the case of formula (1A)) of formulas (1A) and (1B) is Ti.5. A complex as set forth in claim 1 , the complex being represented by formula (1A).6. A complex having nitrogen atoms incorporated therein by bringing a complex as set forth in and nitrogen molecules into contact with each other.9. A method for synthesizing ammonia claim 1 , comprising the step of bringing hydrogen molecules and nitrogen molecules into contact with a complex as set forth in .10. A fixed bed for use in ammonia synthesis claim 1 , comprising a complex as set forth in claim 1 , the complex being fixed.11. A method for synthesizing ammonia claim 6 , comprising the step of brining hydrogen molecules into contact with a complex as set forth in .12. A method for synthesizing ammonia claim 7 , comprising the step of brining hydrogen molecules into contact with a complex as set forth in .13. A method for synthesizing ammonia claim 8 , comprising the step of bringing hydrogen molecules and nitrogen molecules into contact with a complex as set forth in .14. A fixed bed for use in ammonia synthesis claim 6 , comprising a complex as set forth in claim 6 , the complex being fixed.15. A fixed bed for use in ammonia synthesis claim 7 , comprising a complex as set forth in claim 7 , the complex being fixed.16. A fixed bed for use in ammonia synthesis claim 8 , comprising a complex as set forth in claim 8 , the complex being fixed. The present invention relates to a novel hydrido complex capable of fixing dinitrogen, a method for synthesizing ...

METHODS FOR PREPARING ARYLPHOSPHINE-BORANE COMPLEXES

A method for preparing phosphine-borane complexes from aryldihalophosphine includes mixing sodium borohydride, a solvent having at least 50 vol % glycol ethers, and the aryldihalophosphine to obtain a solution. The solution is maintained at a reaction temperature for a duration of time to obtain the phosphine-borane complexes. The solvent may include 1,2-dimethoxyethane and tetrahydrofuran. A ratio of tetrahydrofuran to 1,2-dimethoxyethane in the solvent may be from 0.1:1.0 to 2.5:1.0. 1. A method for preparing phosphine-borane complexes from aryldihalophosphine comprising:mixing sodium borohydride, a solvent comprising at least 50 vol % glycol ethers, and the aryldihalophosphine to obtain a solution; andmaintaining the solution at a reaction temperature for a duration of time to obtain the phosphine-borane complexes.2. The method of claim 1 , wherein the solution is adjusted to the reaction temperature.3. The method of claim 1 , wherein mixing the sodium borohydride claim 1 , the solvent comprising at least 50 vol % glycol ethers claim 1 , and the aryldihalophosphine comprises adding the sodium borohydride and aryldihalophosphine to the solvent comprising at least 50 vol % glycol ethers claim 1 , andthe solvent comprising at least 50 vol % glycol ethers is adjusted to the reaction temperature before adding the sodium borohydride and aryldihalophosphine to the solvent comprising at least 50 vol % glycol ethers.4. The method of claim 1 , wherein the aryldihalophosphine is an aryldicholorophosphine.5. The method of claim 1 , wherein the aryldihalophosphine is a mono-aryldichlorophosphine.6. The method of claim 1 , wherein the aryldihalophosphine is selected from the group consisting of dichloro(2 claim 1 ,4-dimethoxyphenyl)phosphine claim 1 , dichloro(2-methoxyphenyl)phosphine claim 1 , and dichlorophenylphosphine.7. The method of claim 1 , wherein the glycol ethers is selected from the group consisting of 1 claim 1 ,2-dimethoxyethane claim 1 , diglyme claim 1 , ...

CARBON-DIOXIDE COMPOUND AND CATALYST

Tetrahedral [MoO] readily binds COto produce a robust [MoO(κ-CO)] that can affect the reduction of COto formate. 1. An isolated compound comprising a molybdate complex of carbon dioxide.2. The compound of claim 1 , wherein the molybdate complex includes a single molybdenum atom.3. The compound of claim 1 , wherein the molybdate complex includes a single carbonate group.4. The compound of claim 3 , wherein the molybdate complex includes [MoO(κ-CO)].5. The compound of claim 1 , wherein the molybdate complex includes two carbonate groups.6. The compound of claim 5 , wherein the molybdate complex includes [MoO(κ-CO)].7. The compound of claim 1 , further comprising a non-coordinating cation.8. The compound of claim 7 , wherein the non-coordinating cation is bis(triphenylphosphine)iminium claim 7 , an ammonium or a phosphonium.9. A method of making an isolated molybdate complex of carbon dioxide comprising:exposing a molybdate to carbon dioxide; and isolating the molybdate complex of carbon dioxide.10. The method of claim 9 , wherein the molybdate is exposed to greater than one atmosphere of carbon dioxide.11. The method of claim 9 , wherein the molybdate complex includes [MoO(κ-CO)].12. A method for carbon dioxide fixation comprising:exposing carbon dioxide to a molybdate in the presence of a mild nucleophile to produce a carbon dioxide-transformed product.13. The method of claim 12 , wherein the mild nucleophile is a mild hydride source.14. The method of claim 13 , wherein the mild hydride source includes a silane or borane.15. The method of claim 12 , wherein the mild nucleophile is an electron-rich alkene or alkyne.16. The method of claim 12 , wherein the mild nucleophile is a metal hydride or metal alkyl.17. The method of claim 12 , wherein the mild nucleophile is an amine. This application claims priority to U.S. Provisional Patent Application No. 61/917,980, filed Dec. 18, 2013, which is incorporated by reference in its entirety.The invention features compounds ...

GOLD(I) COMPLEXES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF TREATING CANCER

Gold(I) complexes and gold(I) dithiocarbamate polymers as anticancer therapeutics. The Au(I) ion within the gold(I) complexes is coordinated to two phosphine ligands. The repeating unit formed by Au(I) ion coordinating to dithiocarbamte ligands are connected by Au(I)-Au(l) interactions within the gold(I) dithiocarbamate polymers. Also disclosed are methods of synthesis, pharmaceutical compositions incorporating the gold(I) complexes, pharmaceutical compositions incorporating the gold(I) dithiocarbamate polymers, and methods of treating cancer. 2: The gold(I) complex of formula (I) of claim 1 , wherein the anion is a halide ion claim 1 , a trifluoromethanesulfonate ion claim 1 , a hexafluorophosphate ion claim 1 , a tetrafluoroborate ion claim 1 , or a perchlorate ion.3: The gold(I) complex of formula (I) of claim 1 , wherein R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , R claim 1 , and Rare a hydrogen claim 1 , and X is Cl.4: A composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'the gold(I) complex of formula (I) of ; and'}a pharmaceutically acceptable carrier and/or excipient.5: The composition of claim 4 , which comprises 0.01-100 μM of the gold(I) complex relative to the total volume of the composition.6: The composition of claim 4 , wherein the pharmaceutically acceptable carrier and/or excipient is at least one selected from the group consisting of an organic solvent claim 4 , an inorganic salt claim 4 , a surfactant claim 4 , and a polymer.7: A method of treating cancer claim 4 , comprising administering the composition of to a subject in need of therapy.8: The method of claim 7 , wherein the cancer is resistant to cisplatin.9: The method of claim 7 , wherein the cancer is at least one selected from the group consisting of lung cancer claim 7 , colon cancer claim 7 , and breast cancer.10: The method of claim 7 , wherein 1-300 mg/kg of gold(I) complex of formula (I) ...

Mixed ligand gold(i) complexes as anti-cancer agents

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF

In one aspect, phosphine compounds comprising three adamantyl moieties (PAd) and associated synthetic routes are described herein. Each adamantyl moiety may be the same or different. For example, each adamantyl moiety (Ad) attached to the phosphorus atom can be independently selected from the group consisting of adamantane, diamantane, triamantane and derivatives thereof. Transition metal complexes comprising PAdligands are also provided for catalytic synthesis including catalytic cross-coupling reactions. 1. A method of synthesizing a tri-(adamantyl)phosphine compound , PAd , comprising:{'sub': 2', '2', 'N', '3, 'providing a reaction mixture including di-(adamantyl)phosphine (PAd) and a substituted adamantyl moiety and reacting the PAdand substituted adamantyl moiety via an S1 pathway to provide the PAd.'}2. The method of claim 1 , wherein adamantyl moieties (Ad) of the PAdare independently selected from the group consisting of adamantane claim 1 , diamantane claim 1 , triamantane and derivatives thereof.3. The method of claim 1 , wherein the substituted adamantyl moiety comprises a leaving group.4. The method of claim 3 , wherein the leaving group is selected from the group consisting of acetate claim 3 , triflate claim 3 , tosylate and hydroxyl.5. The method of claim 1 , wherein yield of the PAdis greater than 50 percent.6. The method of claim 1 , wherein yield of the PAdis greater than 60 percent.7. A method of cross-coupling comprising:{'sub': '3', 'providing a reaction mixture including a substrate, a coupling partner and a transition metal complex comprising PAdligand; and'}reacting the substrate and coupling partner in the presence of the transition metal complex or derivative thereof to provide cross-coupled reaction product.8. The method of claim 7 , wherein the transition metal complex comprises one or more metals selected from Group VIIIA claim 7 , IB or IIB of the Periodic Table.9. The method of claim 7 , wherein the transition metal complex comprises ...

HYDROGENATION OF ESTERS WITH FE/TRIDENTATE LIGANDS COMPLEXES

The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of Fe complexes with tridentate ligands, having one amino or imino coordinating group and two phosphino coordinating groups, in hydrogenation processes for the reduction of ketones, aldehydes, esters or lactones into the corresponding alcohol or diol, respectively. 1. A process for the reduction by hydrogenation , using molecular H , of a C-Csubstrate containing one or two carbonyl or carboxylic functional group into the corresponding alcohol , or diol , characterized in that said process is carried out in the presence of a base and at least one catalyst or pre-catalyst in the form of a iron complex of formula{'br': None, 'sub': a', 'b, '[Fe(L3)(L′)Y](Z)\u2003\u2003(1)'}wherein L3 represents a tridentate ligand wherein the coordinating groups consist of one amino or imino group and two phosphino groups;{'sub': '1-11', 'L′ represents a CO or Cisonitrile compound;'}{'sub': 1', '6', '4', '4, 'each Y represents, simultaneously or independently, a hydrogen or halogen atom, a hydroxyl group, or a C-Calkoxy or carboxylic radical or a BHor AlHgroup;'}{'sub': 1', '6', '4', '4, 'each Z represents, simultaneously or independently, a halogen atom, a hydroxyl group, or a C-Calkoxy or carboxylic radical or a BHor AlHgroup; and'}(a+b)=2 with a being 1 or 2.2. A process according to claim 1 , wherein said complex is of formula{'br': None, 'sub': '2', '[Fe(L3)(L′)Y]\u2003\u2003(2)'}{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'wherein L3 L′ and Y have the same meaning as in .'}6. A process according to claim 5 , characterized in that said substrate is a compound of formula (I) wherein Rrepresent a hydrogen atom or a Rgroup claim 5 , and each R claim 5 , when taken separately claim 5 , represent simultaneously or independently a linear claim 5 , branched or cyclic C-Caromatic claim 5 , alkyl claim 5 , alkenyl or alkanedienyl group optionally substituted; or Rand Rare bonded ...

HYDROGENATION OF ESTERS WITH FE/TRIDENTATE LIGANDS COMPLEXES

The present invention relates to certain iron complexes that have utility in the field of catalytic hydrogenation and, more particularly, to certain iron complexes of tridentate ligands having one amino or imino coordinating groups and two phosphino coordinating groups. These iron complexes can be used in hydrogenation processes for the reduction of ketones, aldehydes, esters or lactones into the corresponding alcohol or diol, respectively. 2. A complex according to claim 1 , wherein L′ represents a CO moiety.3. A complex according to claim 1 , wherein the tridentate L3 ligand is a C-Cor a C-Ccompound.4. A complex according to claim 1 , wherein each Y represents claim 1 , simultaneously or independently claim 1 , a hydrogen or chlorine or bromine atom claim 1 , a methoxy claim 1 , ethoxy or isopropoxy radical claim 1 , or a BHgroup.5. A complex according to claim 1 , wherein each Z represents claim 1 , simultaneously or independently claim 1 , a chlorine or bromine atom claim 1 , a methoxy claim 1 , ethoxy or isopropoxy radical claim 1 , or a BHgroup. This application is a division of U.S. application Ser. No. 15/105,927 filed Jun. 27, 2016, which is a 371 filing of International patent application no. PCT/EP2014/077217 filed Dec. 10, 2014, which claims the benefit of European patent application no. 13198076.5 filed Dec. 18, 2013, the entire content of each of which is incorporated herein by reference thereto.The present invention relates to the field of catalytic hydrogenation and, more particularly, to the use of Fe complexes with tridentate ligands, in hydrogenation processes for the reduction of esters, lactones, ketones or aldehydes into the corresponding alcohol or diol, respectively.Reduction of an ester functional group to the corresponding alcohol is one of the fundamental reactions in organic chemistry, and is used in a large number of chemical processes.In general, two main types of processes are known to achieve such a transformation. Such types of ...

PRODUCTION OF LITHIUM DIPHENYLPHOSPHIDE

Lithium diphenylphosphide solutions in a solvent, e.g., diethoxymethane (DEM), that are more stable than when tetrahydrofuran (THF) is used as a solvent. Methods of producing them are also disclosed. 122-. (canceled)23. A solution comprising lithium diphenylphosphide , an initiator , and a solvent that yields a more stable solution than when the solution contains tetrahydrofuran as a solvent.24. The solution of claim 23 , wherein the solvent comprises an organic solvent.25. The solution of claim 24 , wherein the organic solvent comprises methyltetrahydrofuran.26. The solution of claim 24 , wherein the solvent comprises 1 to 5 carbon atoms.27. The solution of claim 23 , wherein the solvent comprises -diethyl ether.28. The solution of claim 23 , wherein the solvent comprises diethoxymethane.29. The solution of claim 23 , wherein the initiator is 1 claim 23 ,2-dibromoethane.30. A method comprising adding chlorodiphenylphosphine together with lithium metal and an initiator in a solvent and reacting to form lithium diphenylphosphide in a solution of the solvent claim 23 , wherein the solvent yields a more stable solution than when a molar equivalent amount of tetrahydrofuran is the solvent.31. The method of claim 30 , wherein the reaction is conducted at a temperature of from 30° C. to 80° C.32. The method of claim 30 , wherein the initiator is 1 claim 30 ,2-dibromoethane.33. The solution of claim 23 , wherein the solvent is an ether that contains 1 or 2 ether units.34. The solution of claim 23 , wherein the solvent is a linear ether.35. The method of claim 30 , wherein the solvent is an ether that contains 1 or 2 ether units.36. The method of claim 23 , wherein the solvent is a linear ether.37. The solution of claim 24 , wherein the organic solvent comprises an ether.38. The solution of claim 23 , wherein the solvent comprises 2-methyltetrahydrofuran.39. The method of claim 30 , wherein the reaction is conducted at a temperature of from greater than 40° C. to 80° C.40. ...

ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME

An organometallic compound represented by MLLand an organic light-emitting device including the same, wherein M may be selected from copper (Cu), cobalt (Co), and nickel (Ni), Lmay be selected from ligands represented by Formula 2, and Lmay be a monovalent organic ligand: 2. The organometallic compound of claim 1 , wherein M is copper (Cu).3. The organometallic compound of claim 1 , wherein Xis selected from P(R)(R) and N(R)(R) claim 1 , and Xis selected from P(R)(R) and N(R)(R).4. The organometallic compound of claim 1 , wherein CYand CYare each independently selected from a benzene claim 1 , a naphthalene claim 1 , a fluorene claim 1 , a spiro-fluorene claim 1 , an indene claim 1 , a pyrrole claim 1 , a thiophene claim 1 , a furan claim 1 , an imidazole claim 1 , a pyrazole claim 1 , a thiazole claim 1 , an isothiazole claim 1 , an oxazole claim 1 , an isoxazole claim 1 , a triazole claim 1 , a pyridine claim 1 , a pyrazine claim 1 , a pyrimidine claim 1 , a pyridazine claim 1 , a quinoline claim 1 , an isoquinoline claim 1 , a benzoquinoline claim 1 , a quinoxaline claim 1 , a quinazoline claim 1 , a carbazole claim 1 , a benzimidazole claim 1 , a benzofuran claim 1 , a benzothiophene claim 1 , an isobenzothiophene claim 1 , a benzoxazole claim 1 , an isobenzoxazole claim 1 , a triazole claim 1 , a tetrazole claim 1 , an oxadiazole claim 1 , a triazine claim 1 , a dibenzofuran claim 1 , a dibenzothiophene claim 1 , a benzofuropyridine claim 1 , and a benzothienopyridine.5. The organometallic compound of claim 1 , wherein CYand CYare each independently selected from a benzene claim 1 , a naphthalene claim 1 , an indene claim 1 , and a pyridine.6. The organometallic compound of claim 1 , wherein Z claim 1 , Z claim 1 , and Rto Rare each independently selected from the group consisting of:{'sub': 1', '20', '1', '20, 'hydrogen, deuterium, —F, —Cl, —Br, —I, a hydroxyl group, a cyano group, a nitro group, an amino group, an amidino group, a hydrazine group, a hydrazone ...

MONONUCLEOTIDE-DITHIOCARBAMATE COMPLEX

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer. 2: The mononucleotide-dithiocarbamate gold complex of claim 1 , wherein Rand Rare the same unsubstituted alkyl group claim 1 , and R claim 1 , R claim 1 , and Rare the same optionally substituted C-Calkyl group.3. (canceled)4: The mononucleotide-dithiocarbamate gold complex of claim 2 , wherein Rand Rare ethyls claim 2 , and R claim 2 , R claim 2 , and Rare methyls.5. (canceled)6: A composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'the mononucleotide-dithiocarbamate gold complex of ; and'}a pharmaceutically acceptable carrier or excipient.78-. (canceled)9: The composition of claim 6 , further comprising:at least one chemotherapeutic agent selected from the group consisting of aflibercept, asparaginase, bleomycin, busulfan, carmustine, chlorambucil, cladribine, cyclophosphamide, cytarabine, dacarbazine, daunorubicin, doxorubicin, etoposide, fludarabine, gemcitabine, hydroxyurea, idarubicin, ifosfamide, irinotecan, lomustine, mechlorethamine, melphalan, mercaptopurine, methotrexate, mitomycin, mitoxantrone, pentostatin, procarbazine, topotecan, vinblastine, vincristine, retinoic acid, oxaliplatin, carboplatin, 5-fluorouracil, teniposide, amasacrine, docetaxel, paclitaxel, vinorelbine, bortezomib, clofarabine, capecitabine, actinomycin D, epirubicin, vindesine, methotrexate, 6-thioguanine, tipifarnib, imatinib, erlotinib, sorafenib, sunitinib, dasatinib, nilotinib, lapatinib, gefitinib, temsirolimus, everolimus, rapamycin, bosutinib, pzopanib, axitinib, neratinib, vatalanib, pazopanib, midostaurin, enzastaurin, trastuzumab, cetuximab, panitumumab, rituximab, bevacizumab, mapatumumab, conatumumab, and lexatumumab. ...

Dna/dithiocarbamato phosphine metal complex

Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.

ANTIBODY-NANOPARTICLE CONJUGATES AND METHODS FOR MAKING AND USING SUCH CONJUGATES

Disclosed herein are antibody-nanoparticle conjugates that include two or more nanoparticles (such as gold, palladium, platinum, silver, copper, nickel, cobalt, iridium, or an alloy of two or more thereof) directly linked to an antibody or fragment thereof through a metal-thiol bond. Methods of making the antibody-nanoparticle conjugates disclosed herein include reacting an arylphosphine-nanoparticle composite with a reduced antibody to produce an antibody-nanoparticle conjugate. Also disclosed herein are methods for detecting a target molecule in a sample that include using an antibody-nanoparticle conjugate (such as the antibody-nanoparticle conjugates described herein) and kits for detecting target molecules utilizing the methods disclosed herein. 19-. (canceled)10. A method for producing an antibody-nanoparticle conjugate , comprising reacting an arylphosphine-nanoparticle composite with a reduced antibody , thereby producing the antibody-nanoparticle conjugate.11. The method of claim 10 , further comprising forming a reduced antibody.12. The method of claim 11 , wherein the reduced antibody is formed by reacting an antibody with a reducing agent to produce the reduced antibody.13. The method of claim 12 , wherein the reducing agent is a mono-thiol compound or a di-thiol compound.14. The method of claim 13 , wherein the reducing agent is dithiothreitol.15. The method of claim 10 , further comprising adjusting reactant stoichiometry and reaction duration to couple two or more nanoparticles to the reduced antibody.16. The method of claim 15 , wherein the antibody-nanoparticle conjugate comprises two to seven nanoparticles.17. The method of claim 16 , wherein the antibody-nanoparticle conjugate comprises five nanoparticles.18. The method of claim 15 , wherein the reactant stoichiometry of the arylphosphine-nanoparticle composite to the reduced antibody is about 7:1 claim 15 , and wherein the number of nanoparticles coupled to the reduced antibody is about five.19. ...

Constrained geometry complexes of titanium, zirconium or hafnium comprising a substituted cyclopentadiene ligand; use as olefin polymerisation catalyst component

Polymerization catalysts

A transition metal complex having the following Formula (A): wherein the monovalent groups R 1 and R 2 are —R a , —OR b , —NR c R d , and —NHR e ; the monovalent groups R a , R b , R c , R d and R e , and the divalent group R 3 are (i) aliphatic hydrocarbon, (ii) alicyclic hydrocarbon, (iii) aromatic hydrocarbon, (iv) alkyl substituted aromatic hydrocarbon (v) heterocyclic groups and (vi) heterosubstituted derivatives of said groups (i) to (v); M is a Group (3) to (11) or lanthanide metal; E is phosphorus or arsenic; X is an anionic group, L is a neutral donor group; n is (1) or (2), y and z are independently zero or integers, such that the number of X and L groups satisfy the valency and oxidation state of the metal M. n is preferably (2) and the two resulting R 1 groups are preferably linked. The complex can be used with optional activator to polymerise olefins

Gas phase polymerization of olefins

A gas phase fluidized bed process is described for producing ethylene polymers having improved processability and an MWD of less than about 2.9. Multiple reactors in series or parallel may be used to produce in-situ blended polymers. Each reactor can separately have a constrained geometry catalyst or a conventional Ziegler-Natta catalyst as needed for obtaining in-situ blended polymer with the desired properties as long as there is a constrained geometry catalyst in at least one reactor. Olefin polymers can be produced according to this invention which have low susceptibility to melt fracture, even under high shear stress conditions.

Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith

Metal coordination complexes comprising a metal of Group 3 (except Sc), 4-10 or the lanthanide series and a delocalized Π-bonded moiety have said moiety substituted with a constrain-inducing moiety which reduces the angle at the metal between the centroid of said Π-bonded moiety and at least one remaining substituted. Preferably, the complexes comprise a cyclopentadienyl or substituted cyclopentadienyl group forming part of a ring structure in which the metal is both bonded to an adjacent convalent moiety and held in association with the (substituted) cyclopentadienyl moiety. Complexes of said preferred structure are not necessarily constrained sufficiently to reduce the said angle. Amidosilane and amidoalkanediyl compounds are particularly preferred. The complexes of the invention form addition polymerization catalysts with activing cocatalysts such as Lewis acids, ammonium salts, oxidizing agents and, especially, aluminum compounds, particularly aluminum trialkyls. Novel polymers, including ElPE resins and pseudo-random copolymers, can be obtained using the catalysts of the invention.

磷杂胍iv族金属烯烃聚合催化剂

实施方案涉及式I的磷杂胍金属络合物和在α‑烯烃聚合体系中使用那些络合物。

Fluorinated N2-phosphinyl amidine compounds, chromium salt complexes, catalyst systems, and their use to oligomerize ethylene

A composition comprising an N 2 -phosphinylamidine chromium salt complex having Structure FNPACr I: wherein CrX p is a chromium salt where X is a monoanion and p is an integer from 2 to 6. A process comprising a) contacting i) ethylene, and ii) a catalyst system comprising an N 2 -phosphinylamidine chromium salt complex having Structure FNPACr I: wherein CrX p is a chromium salt where X is a monoanion and p is an integer from 2 to 6; and b) forming an oligomer product in a reaction zone.

Constrained geometry addition polymerization catalysts

Metal complexes having constrained geometry and a process for preparation thereof, addition polymerization catalysts formed therefrom, processes for preparation of such addition polymerization catalysts, methods of use, and novel polymers formed thereby, including ElPE resins and pseudo-random copolymers, are disclosed and claimed.

Olefin polymerization process using supported constrained geometry catalysts

Metal complexes having constrained geometry and a process for preparation thereof, addition polymerization catalysts formed therefrom, processes for preparation of such addition polymerization catalysts, methods of use, and novel polymers formed thereby, including ElPE resins and pseudo-random copolymers, are disclosed and claimed.

Constrained geometry addition polymerization catalysts

Metal complexes having constrained geometry and a process for preparation thereof, addition polymerization catalysts formed therefrom, processes for preparation of such addition polymerization catalysts, methods of use, and novel polymers formed thereby, including EIPE resins and pseudo-random copolymers, are disclosed and claimed.

Phosphaguanidine group iv metal olefin polymerization catalysts

Embodiments are directed to phosphaguanidine metal complexes of formula I and using those complexes in α-olefin polymerization systems.

Phosphaguanidine group IV metal olefin polymerization catalysts

Embodiments are directed to phosphaguanidine metal complexes of formula I and using those complexes in α-olefin polymerization systems.

Process for the carbonylation of ethylenically unsaturated compouds

A process for the carbonylation of ethylenically unsaturated compounds is described. The process comprises reacting an ethylenically unsaturated compound with carbon monoxide in the presence of a source of hydroxyl groups and a catalyst system. The catalyst system is obtained by combining: (a) metal of Group VIII or a compound thereof: and (b) a bidentate phosphine of general formula (I) The carbonylation reaction is carried out at a temperature of between -30°C to 49°C and under a CO partial pressure of less than 30 x105 N.m-2.

Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith

Hafnium or zirconium coordination complexes comprise a cyclopentadienyl or substituted cyclopentadienyl group forming part of a ring structure in which the metal is both bonded to an adjacent amidosilane moiety and held in association with the (substituted) cyclopentadienyl moiety. These complexes form addition polymerization catalysts with activating cocatalysts such as Lewis acids, ammonium salts, oxidizing agents and, especially, aluminum compounds, particularly aluminum trialkyls. Novel polymers, including ElPE resins and pseudo-random copolymers, can be obtained using the catalysts.

Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith

Titanium coordination complexes comprise a cyclopentadienyl or substituted cyclopentadienyl group forming part of a ring structure in which the metal is both bonded to the (substituted) cyclopentadienyl group by a divalent moiety of specified type containing one or more heteroatoms and held in association with the (substituted) cyclopentadienyl moiety. These complexes form addition polymerization catalysts with activating cocatalysts such as Lewis acids, ammonium salts, oxidizing agents and, especially, aluminum compounds, particularly aluminum trialkyls. Novel polymers, including ElPE resins and pseudo-random copolymers, can be obtained using the catalysts.

Polymers obtainable with a constrained geometry addition polymerization catalyst and process of making atactic alpha-olefin polymers with such catalysts

One or more addition polymerizable monomers are polymerized by catalysts comprising a metal monocyclopentadienyl coordination complex and an activating cocatalyst to form novel polymers, including atactic amorphous poly(alpha-olefins), elastic polyethylenes and pseudo-random copolymers.

Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith

Hafnium or zirconium coordination complexes comprise a cyclopentadienyl or substituted cyclopentadienyl group forming part of a ring structure in which the metal is both bonded to an adjacent amidosilane moiety and held in association with the (substituted) cyclopentadienyl moiety. These complexes form addition polymerization catalysts with activating cocatalysts such as Lewis acids, ammonium salts, oxidizing agents and, especially, aluminum compounds, particularly aluminum trialkyls. Novel polymers, including ElPE resins and pseudo-random copolymers, can be obtained using the catalysts.

Polymers obtainable with a constrained geometry addition polymerization catalyst and process of making atactic alpha-olefin polymers with such catalysts

One or more addition polymerizable monomers are polymerized by catalysts comprising a metal monocyclopentadienyl coordination complex and an activating cocatalyst to form novel polymers, including atactic amorphous poly(alpha-olefins), elastic polyethylenes and pseudo-random copolymers.

Constrained geometry addition polymerization catalysts, processes for their preparation, precursors therefor, methods of use, and novel polymers formed therewith

Integrated process for preparation of diene complexes

Disclosed is a process for preparing bridged Group 4 metal complexes containing a neutral diene ligand starting from the corresponding novel, metal diene containing complexes by reaction thereof with the divalent derivative of a bridged bidentate ligand compound. The novel, intermediate metal diene complexes, their formation from tetravalent metal salts and an integrated process combining both process steps are claimed.

含镍硅氢加成催化剂及含有该催化剂的组合物

本发明公开了一种组合物，所述组合物含有(A)硅氢加成反应催化剂和(B)脂族不饱和化合物，所述脂族不饱和化合物平均每分子具有一个或多个能够进行硅氢加成反应的脂族不饱和有机基团。所述组合物能够通过硅氢加成反应来反应而形成反应产物，如硅烷、树胶、凝胶、橡胶或树脂。成分(A)含有金属‑配体络合物，所述金属‑配体络合物可以通过包括使金属前体与配体反应的方法来制备。

Ruthenium containing hydrosilylation catalysts and compositions containing the catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition ' capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Iridium containing hydrosilylation catalysts and compositions containing the catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition ' capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Supported constrained geometry olefin polymerization catalysts

Metal complexes having constrained geometry and a process for preparation thereof, addition polymerization catalysts formed therefrom, processes for preparation of such addition polymerization catalysts, methods of use, and novel polymers formed thereby, including ElPE resins and pseudo-random copolymers, are disclosed and claimed.

Polymerisation catalysts

A transition metal complex having the following Formula (A): wherein the monovalent groups R 1 and R 2 are —R a , —OR b , —NR c R d , and —NHR e : the monovalent groups R a , R b , R c , R d and R e , and the divalent group R 3 are (i) aliphatic hydrocarbon, (ii) alicyclic hydrocarbon, (iii) aromatic hydrocarbon, (iv) alkyl substituted aromatic hydrocarbon (v) heterocyclic groups and (vi) heterosubstituted derivatives of said groups (i) to (v); M is a Group (3) to (11) or lanthanide metal; E is phosphorus or arsenic; X is an anionic group, L is a neutral donor group; n is (1) or (2), y and z are independently zero or integers, such that the number of X and L groups satisfy the valency and oxidation state of the metal M. n is preferably (2) and the two resulting R 1 groups are preferably linked. The complex can be used with optional activator to polymerise olefins.

用于制备二烯配合物的联合法

公开了一种含中性二烯配体的桥连第4族金属配合物的制备方法，由相应的新的含二烯烃的金属配合物开始，通过与桥连的二齿配体化合物的二价衍生物反应制备。权利要求书要求了这种新的中间金属二烯配合物、由四价金属盐形成其的方法、及合并了两工艺步骤的联合法。

用于制备二烯配合物的联合法

公开了一种含中性二烯配体的桥连第4族金属配合物的制备方法,由相应的新的含二烯烃的金属配合物开始,通过与桥连的二齿配体化合物的二价衍生物反应制备。权利要求书要求了这种新的中间金属二烯配合物、由四价金属盐形成其的方法、及合并了两工艺步骤的联合法。

Trimerisation and oligomerisation of olefins using a chromium based catalyst

The invention provides a olefin oligomerisation catalyst system that includes: a multidentate mixed heteroatomic ligand, which ligand includes three donor heteroatoms of which one donor heteroatom is sulfur, one donor heteroatom is nitrogen and one donor heteroatom is a phosphorous atom and wherein the ligand is selected such that none of the donor heteroatoms are directly bonded to any of the other donor heteroatoms; and chromium; wherein the ligand is of the following type: R 1 A(R 2 BR 3 R 4 )(R 5 CR 6 ) wherein R 1 , R 3 , R 4 and R 6 may be hydrogen or independently be selected from the groups consisting of alkyl, aryl, aryloxy, halogen, nitro, alkoxycarbonyl, carbonyloxy, alkoxy, aminocarbonyl, carbonylamino, dialkylamino, or derivatives thereof, or aryl substituted with any of these substituents; R 2 and R 5 may be the same or different and are C 1 to C 15 hydrocarbyls; A is nitrogen; B is phosphorous; and C is sulfur. The invention also provides a process for the oligomerisation of olefins including the step of contacting the olefins with such a catalyst system.

hydrocarbon conversion catalyst system; and process for oligomerization of olefins.

Metal containing hydrosilylation catalysts and compositions containing the catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

INTEGRATED METHOD FOR THE PRODUCTION OF SERVE COMPLEXES

Nickel containing hydrosilylation catalysts and compositions containing the catalysts

Iron containing hydrosilylation catalysts and compositions containing the catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Integrated process for preparation of diene complexes

Olefin polymers formed by use of constrained geometry addition polymerization catalysts

Metal complexes having constrained geometry and a process for preparation thereof, addition polymerization catalysts formed therefrom, processes for preparation of such addition polymerization catalysts, methods of use, and novel polymers formed thereby, including ElPE resins and pseudo-random copolymers, are disclosed and claimed.

Hafnium containing hydrosilylation catalysts and compositions containing the catalysts

A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains a metal-ligand complex that can be prepared by a method including reacting a metal precursor and a ligand.

Trimerisation and oligomerisation of olefins using a chromium based catalyst

The invention provides a mixed heteroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms, of which at least one heteroatom is nitrogen and at least two heteroatoms are not the same. The invention also provides a multidentate mixed heroatomic ligand for an oligomerisation of olefins catalyst, which ligand includes at least three heteroatoms. At least one heteroatom may be nitrogen and at least 2 heteroatoms may not be the same.

Polymerisation catalysts

Homogeneous hydroformylation catalysis with silyl substituted alkyl diaryl phosphine metal complexes

Described is a carbonylation process using novel homogeneous trihydrocarbyl silyl-substituted alkyl diaryl phosphine transition metal complexes of the general formula: [(Ar.sub.2 PQ).sub.y SiR.sub.4 -y].sub.g (MX.sub.n).sub.s wherein Ar is a C 6 to C 10 aromatic hydrocarbyl radical, Q is a C 1 to C 30 saturated straight chain divalent radical, R is a C 1 to C 10 hydrocarbyl, wherein Ar, Q and R, can be substituted or unsubstituted, y is 1 to 4, g times y is 1 to 6, M is a transition metal selected from the group consisting of Group VIII transition metals, X is an anion or organic ligand excluding halogen satisfying the valence and coordination sites of the metal, n is 2 to 6 and s is 1 to 3, are disclosed. These materials exhibit high thermal stability and are superior catalysts for the selective hydroformylation of olefins, particularly in the presence of excess quantities of ligand of the formula: (Ar.sub.2 PQ).sub.y SiR.sub.4-y wherein Ar, Q, R, and y are as previously defined. Specifically, tris-(trimethyl silyl-ethyl diphenyl phosphine) rhodium carbonyl hydride, [(CH.sub.3).sub.3 Si--CH.sub.2 CH.sub.2 --PPh.sub.2 ].sub.3 Rh(CO)H and tris [bis-(diphenylphosphinoethyl)dimethylsilane] rhodium carbonyl hydride, [(CH.sub.3).sub.2 Si--CH.sub.2 CH.sub.2 --PPh.sub.2 ].sub.3 Rh(CO)H, are selective olefin hydroformulation catalysts, particularly in the presence of excess trihydrocarbyl silyl-substituted alkyl diaryl phosphine ligand.

Trihydrocarbyl silyl substituted alkyl diaryl phosphine transition metal complexes and their use as homogeneous isomerization hydroformylation catalysts

Described is a carbonylation process using novel homogeneous trihydrocarbyl silyl-substituted alkyl diaryl phosphine transition metal complexes of the general formula: [(Ar.sub.2 PQ).sub.y SiR.sub.4 --y].sub.g (MX.sub.n).sub.s wherein Ar is a C 6 to C 10 aromatic hydrocarbyl radical, Q is a C 1 to C 30 saturated straight chain divalent radical, R is a C 1 to C 10 hydrocarbyl, wherein Ar, Q and R, can be substituted or unsubstituted, y is 1 to 4, g times y is 1 to 6, M is a transition metal selected from the group consisting of Group VIII transition metals, X is an anion or organic ligand excluding halogen satisfying the valence and coordination sites of the metal, n is 2 to 6 and s is 1 to 3, are disclosed. These materials exhibit high thermal stability and are superior catalysts for the selective hydroformylation of olefins, particularly in the presence of excess quantities of ligand of the formula: (Ar.sub.2 PQ)ySiR.sub.4-y wherein Ar, Q, R, and y are as previously defined. Specifically, tris-(trimethyl silyl-ethyl diphenyl phosphine) rhodium carbonyl hydride, [(CH.sub.3).sub.3 Si--CH.sub.2 CH.sub.2 --PPh.sub.2 ].sub.3 Rh(CO)H and tris [bis-(diphenylphosphinoethyl)dimethyl silane] rhodium carbonyl hydride, [(CH.sub.3).sub.2 Si--CH.sub.2 CH.sub.2 --PPh.sub.2 ].sub.3 Rh(CO)H, are selective olefin hydroformylation catalysts, particularly in the presence of excess trihydrocarbyl silyl-substituted alkyl diaryl phosphine ligand.

Sulfonated phenyl phosphine-containing complexes

The invention relates to novel complex compounds of elements from groups VII A, VIII A and I B of the Periodic Table with the trisodium salt of tris(m-sulphophenyl)phosphine as complex ligands, and to the use of these complex compounds as catalysts for hydrogenations, for the water gas reaction, for hydrocarbonylations, hydroformylations, oxidations, C-C linking reactions (e.g. allene/alkyne coupling) and addition reactions of secondary amines with C-C double bonds.

Sulfonated phenyl phosphine-containing complexes

Gegenstand der Erfindung sind neue Komplexverbindungen von Elementen der Gruppen VII A, VIII A und I B des Perioden­ systems mit dem Trinatriumsalz von Tris(m-sulfophenyl)­ phosphan als Komplexliganden und die Verwendung dieser Komplexverbindungen als Katalysatoren für Hydrierungen für die Wassergas-Reaktion, für Hydrocarbonylierungen, Hydro­ formylierungen, Oxidationen, C-C-Verknüpfungsreaktionen (z.B. Allen/Alkin-Kupplung) und Additionen von sekundären Aminen an C-C-Doppelbindungen. The invention relates to new complex compounds of Elements of groups VII A, VIII A and I B of the periods systems with the trisodium salt from Tris (m-sulfophenyl) phosphane as complex ligands and the use of these Complex compounds as catalysts for hydrogenations for the water gas reaction, for hydrocarbonylation, hydro formylations, oxidations, C-C coupling reactions (e.g. Allen / alkyne coupling) and additions of secondary ones Amines on C-C double bonds.