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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 28. Отображено 28.
12-05-2023 дата публикации

Tubular passive sampler adsorption phase for determining perfluorinated compounds in water

Номер: CN116099512A
Автор: CHEN CHANG'ER, LI SILIN, LIU SISI, CHENG SHENGMING, YING GUANGGUO
Принадлежит:

The invention relates to the technical field of environmental monitoring, and discloses a tubular passive sampler adsorption phase for determining perfluorinated compounds in water, which is prepared by the following steps: S1, purifying and activating a WAX adsorbent by using methanol, dissolving impurities on adsorption binding sites on the WAX adsorbent in methanol, and then leaching by using ultrapure water; s2, uniformly mixing the washed WAX adsorbent and 10mL of cross-linking agent-polyacrylamide sol according to the mass ratio of 2: 5, then sequentially adding 160mu L of 10% ammonium persulfate solution and 30mu L of catalyst N, N, N 'N' tetramethylethylenediamine solution, and continuously and uniformly mixing; and S3, injecting a proper amount of the solution into a PE pipe, sealing the two ends of the PE pipe, placing the PE pipe in a rolling mixer, rolling the PE pipe at the rotating speed of 70rpm for 10min to form gel, then cutting the PE pipe open, and completely taking out ...

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Номер записи: 1
16-05-2023 дата публикации

Probe primer group, kit and detection method for detecting bacteria through multiple qPCR (quantitative polymerase chain reaction)

Номер: CN116121409A
Автор: SHAO YANG, LIU JIA, ZHAO MINCHAO, NA CHENGLONG, LIU SISI, CUI YUELI, GUO YAO, WU WEIWEI, JIANG WEN
Принадлежит:

The invention provides a probe primer group and a detection method for detecting four bacteria in a sample by a multiple qPCR (quantitative polymerase chain reaction) technology. Specific primers and probes are designed according to gene sequences of four clinical high-frequency detected pathogenic bacteria, namely acinetobacter baumannii, klebsiella pneumoniae, stenotrophomonas maltophilia and pseudomonas aeruginosa, and whether a sample is infected by four bacteria or not is simultaneously identified by utilizing multiple qPCR, so that the reaction conditions and the detection process are optimized, the detection time is shortened, and the detection efficiency is improved. For clinical infected patients, rapid and accurate differential diagnosis of pathogens has important significance for adjuvant therapy, medication and improvement of prognosis. Meanwhile, the multiple primer probe group and the detection method have good specificity, high accuracy and good repeatability, also have the ...

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Номер записи: 2
30-05-2023 дата публикации

Intellectual property service management method and system based on structure tree

Номер: CN116187958A
Автор: PAN XIAOYAN, LIU SISI, XU CHUNMEI
Принадлежит:

The invention provides an intellectual property service management method and system based on a structure tree, and the method comprises the steps: constructing an intellectual property service problem-problem solution structure tree; monitoring an intellectual property service problem in an intellectual property service mechanism; and determining a problem solution corresponding to the monitored intellectual property service problem from the intellectual property service problem-problem solution structure tree, and pushing the problem solution to a corresponding problem source. According to the intellectual property service management method based on the structure tree provided by the invention, when a service problem is encountered by a worker in butt joint with a client, the system can automatically monitor the problem and give a problem solution to the worker, and the worker can timely view the problem and solve the service problem based on the problem solution; and the problem can ...

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Номер записи: 3
22-08-2019 дата публикации

DETECTION METHOD AND DEVICE OF COPY NUMBER VARIATIONS, AND COMPUTER READABLE MEDIUM

Номер: WO2019157791A1
Автор: SHAO, Yang, WANG, Xiaonan, WU, Xue, CHANG, Zhili, LIU, Sisi, NA, Chenglong
Принадлежит:

The present invention relates to the technical field of bioinformatics, and provides a detection method and device for gene fragment copy number variations, and a computer readable medium, and in particular, provides a method for detecting gene fragment copy number variations based on next generation sequencing (NGS) data. When the detection method for gene fragment copy number variations provided by the present invention is applied to the NGS sequencing process of a group of genes (panel) formed by a plurality of detection regions, an average sequencing depth is obtained by means of T distribution fitting, and thus a copy number baseline is calculated, and an abnormal gene fragment is analyzed. According to the analysis method, the impacts of fluctuation of sequencing depths of the detection regions caused by NGS test methods on detection results are effectively eliminated, and problems of high copy numerical-value fluctuation caused by sequencing depth increase/decrease of other regions ...

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Номер записи: 4
23-05-2023 дата публикации

Multiple primer group, method and kit for detecting cerebrospinal fluid pathogens

Номер: CN116144811A
Автор: SHAO YANG, LIU JIA, ZHAO MINCHAO, NA CHENGLONG, LIU SISI, CUI YUELI, GUO YAO, WU WEIWEI, JIANG WEN
Принадлежит:

The invention discloses a multiple primer group, a method and a kit for detecting pathogenic microorganisms in cerebrospinal fluid and application of the multiple primer group, and belongs to the technical field of microorganism detection. 40 important pathogens including 13 bacteria, 6 fungi, 15 parasites and 6 DNA viruses in a cerebrospinal fluid sample are specifically detected, common pathogens of central nervous system infection are accurately covered, the sensitivity and specificity of pathogenic microorganism detection in the cerebrospinal fluid sample are improved, and more accurate broad-spectrum detection of the pathogens is achieved.

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Номер записи: 5
04-08-2023 дата публикации

HTTP (Hyper Text Transport Protocol) message rule matching method, system, equipment and medium

Номер: CN116545701A
Автор: LU SHIDA, JIN LINGLI, YAO YIFAN, ZHANG LISHOU, LIU SISI, ZHAO CHUAN, WANG HUAN, CHEN YUMING, JI FENFEN, CHEN JIEQUAN
Принадлежит:

The invention discloses an HTTP (Hyper Text Transport Protocol) message rule matching method, system and device and a medium, and the method comprises the steps: analyzing an obtained HTTP message, and obtaining an analyzed HTTP message; a configuration file used for HTTP message rule matching is read and analyzed, and a user-defined rule set is generated; the Head part is extracted, and extraction information is obtained; performing character string matching on the body part according to a user-defined rule set based on an improved multimode matching algorithm of an AC automaton; recording the occurrence frequency and position of the matched character string in the body part information in each matching rule; determining a preliminary matching result according to the extraction information and a multimode matching result; performing position matching operation on the preliminary matching result according to the position information to obtain an accurate matching result, namely an HTTP ...

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Номер записи: 6
15-08-2023 дата публикации

Preparation method of inhibitor containing camellia saponin and application of inhibitor in inhibition of expression of bacillus cereus emetic toxin

Номер: CN116584509A
Автор: GAO YIDAN, LIU SISI, MA YINGZI, LEE CHANG-JU, LIU RUKUAN, XIAO ZHIHONG, TU JIA, XIAO JINGJING, LI LI, JI YUENA
Принадлежит:

The invention discloses a preparation method of an inhibitor containing camellia saponin and application of the inhibitor in inhibition of expression of bacillus cereus emetic toxin, and relates to the technical field of inhibitors, the preparation method of the inhibitor containing camellia saponin comprises the following steps: S1, extracting camellia saponin; S2, extracting a lemon extract, a shaddock peel extract and a dandelion extract; the camellia saponin, the lemon extract, the shaddock peel extract, the dandelion extract and the sodium benzoate in the S1 are mixed to prepare an inhibitor, the mass concentration of the camellia saponin is 85%-95%, the mass concentration of the lemon extract, the mass concentration of the shaddock peel extract and the mass concentration of the dandelion extract are 2%-10%, and the mass concentration of the sodium benzoate is 0.1%-0.2%; the inhibitor obtained by the preparation method provided by the invention has an obvious growth inhibition effect ...

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Номер записи: 7
05-05-2023 дата публикации

Vibroseis forward modeling method and device, storage medium and electronic equipment

Номер: CN116068630A
Автор: CHENG YUN, LIU XIAOMIN, GAO YANXIA, LIU SISI, SUN ZHIFENG, JIANG BO
Принадлежит:

The invention relates to the technical field of physical exploration, in particular to a vibroseis forward modeling method and device, a storage medium and electronic equipment, and the method comprises the steps: building a speed model according to the geological features of a target desert area; setting an observation system, a seismic source wavelet type, a frequency scanning mode, a frequency scanning range and a signal scanning length according to the speed model; starting forward modeling to obtain a scanning signal and a seismic source record; and performing cross-correlation on the scanning signal and the seismic source record to obtain a single shot record. According to the method, desert surface vibroseis data acquisition can be accurately simulated, the research requirement of noise suppression of data acquired by the desert surface vibroseis at present is met, and technical support is provided for formation mechanism analysis of seismic exploration noise in a desert area and ...

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Номер записи: 8
04-04-2023 дата публикации

Camellia oleifera cake extract and application thereof in metal corrosion inhibition

Номер: CN115894599A
Автор: XIAO JINGJING, LEE CHANG-JU, XIAO ZHIHONG, JIANG DALIANG, LIU SISI, TU JIA, LIU RUKUAN, ZHANG AIHUA, LI LI, LI PEIWANG
Принадлежит:

The invention belongs to the technical field of corrosion inhibitors, and relates to an oil tea cake extract and application thereof in metal corrosion inhibition. Water, ethyl alcohol or a mixed solution of the water and the ethyl alcohol is used as a solvent, and a solid mixture is extracted from oil tea processing residues, namely oil tea cakes. The molecular structure of the main component tea saponin of the mixture contains a large amount of-OH,-COOH,-COOR, C = C and other unsaturated covalent bonds, and the heteroatoms as adsorption centers have relatively high electron density, so that pi bonds and feedback pi bonds are generated between tea saponin molecules and metals; and therefore, an effective passive film is formed on the metal surface in a covering manner to block electrochemical reaction, and the effect of retarding metal corrosion is achieved. The product belongs to a natural plant extract extracted from waste oil tea cakes, has the characteristics of low cost, environmental ...

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Номер записи: 9
15-08-2023 дата публикации

Matrix interference resistant virus direct cracking lysate

Номер: CN116590380A
Автор: SHAO YANG, SONG DANNI, CAI XUSHEN, LIU SISI, YANG ZHEN
Принадлежит:

The invention relates to a virus direct cracking lysis buffer capable of resisting sample matrix interference, and belongs to the technical field of virus detection. The direct lysis solution comprises the following components in concentration: 0.01 to 0.5 M of NaOH, 0.01 to 0.5% (v/v) of TritonX100, 0.1 to 5% of formamide/DMSO, 1 to 100 mM of ammonium sulfate, 1 to 10 mM of spermidine, 0.01 to 1% (v/v) of BSA, 1 to 10% (v/v) of glycerin, 10 to 100 mM of KCl, and 0.1 to 50 mM of MEDTA/EGTA. Interference of a traditional cracking method on downstream reaction is overcome, and a cracking product does not need to be extracted and purified. (1) the cracking only needs 2-10 minutes, extraction is avoided, and the operation is simple and convenient; (2) an effective anti-matrix interference component is obtained, a cracked product can be directly applied to an isothermal amplification downstream reaction without purification, and reaction inhibition is not caused; (3) the unique enzyme stabilization ...

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Номер записи: 10
18-07-2023 дата публикации

Nucleic acid detection card based on knob isolating valve and detection method

Номер: CN116445269A
Автор: SHAO YANG, REN YUE, YANG ZHEN, WANG QIANG, JIANG SIMING, LIU SISI
Принадлежит:

The invention relates to the technical field of nucleic acid detection, in particular to a nucleic acid detection card based on a knob isolating valve and a nucleic acid detection method. The nucleic acid detection card is provided with a reagent tube, the reagent tube is movably connected into a test tube seat in a pluggable mode and provided with a test tube cover, a knob isolation valve and a test tube body, the knob isolation valve is provided with a first storage chamber and a valve shell, the top of the first storage chamber is connected with the openable test tube cover, and the bottom of the first storage chamber is inserted into the bottom of the valve shell to be sealed. Meanwhile, at least one leakage groove is formed in the side face, close to the bottom, of the valve shell, and when the leakage groove is separated from the bottom of the valve shell at the bottom of the first storage chamber, liquid stored in the first storage chamber automatically leaks; the test tube body ...

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Номер записи: 11
23-05-2023 дата публикации

Application of gene marker in early screening of malignant breast cancer and benign breast nodule and construction method of screening model

Номер: CN116153420A
Автор: SHAO YANG, WU XUE, BAO HUA, LIU RUI, WU SHUYU, JOAN SHOFU, TANG SHITING, LIU SISI
Принадлежит:

The invention relates to application of a gene marker in early screening of malignant breast cancer and benign breast nodules and a construction method of a screening model, liquid biopsy whole genome WGS low-depth sequencing is carried out on a plasma sample cfDNA, and window copy number change analysis (CNV) between the malignant breast cancer and the benign nodules is carried out on a high-throughput sequencing result, so that the malignant breast cancer and benign nodules are screened. A multi-feature and multi-algorithm integrated model is constructed by utilizing automatic machine learning according to a DNA fragment distribution difference (FSD), a DNA fragment length ratio difference (FSR), a DNA breakpoint sequence (BPM) and a DNA terminal sequence (EDM), so that the aim of non-invasive accurate diagnosis of breast cancer is fulfilled.

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Номер записи: 12
19-05-2023 дата публикации

Variable-pitch multi-needle clamping device for sewing multilayer stacked carbon fiber fabric

Номер: CN116136041A
Автор: MEI MING, ZENG TAI, HE YUJIA, JIANG SHENGQIANG, LIU JINGANG, LIU SISI
Принадлежит:

The invention discloses a variable-pitch multi-needle clamping device for sewing multilayer stacked carbon fiber fabrics, the variable-pitch multi-needle clamping device comprises a sewing needle clamping module, a cam variable-pitch module and a cam clamping module, the sewing needle clamping module is used for clamping a sewing needle with a sewing thread; a cam shaft in the cam variable-pitch module is provided with cam grooves of which the number of turns is the same and the screw pitches are sequentially increased from the middle to the two sides, and the cam grooves are used for controlling the distances between all adjacent sewing needle clamping modules to be synchronously increased so as to achieve a variable-pitch effect; the cam clamping module controls clamping blocks in the sewing needle clamping module installed on the cam clamping module to synchronously control clamping and releasing of all sewing needles. Synchronous clamping actions of all the sewing needles are achieved ...

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Номер записи: 13
28-04-2023 дата публикации

Multi-layer stacked carbon fiber fabric single-line sewing robot

Номер: CN116024738A
Автор: JIANG SHENGQIANG, ZENG TAI, MEI MING, HE YUJIA, LIU JINGANG, LIU SISI
Принадлежит:

The invention discloses a multi-layer stacked carbon fiber fabric single-thread sewing robot which is composed of a workbench, a clamping device, a sewing needle puncturing mechanism, a thread pulling mechanism and a needle and thread storage mechanism, and the clamping device is used for fixing the multi-layer stacked carbon fiber fabric; the two suture needle puncture mechanisms are arranged on the two sides of the clamping device respectively and used for simulating the puncture action of a suture needle in the manual suture process. The two suture pulling mechanisms are arranged on the two sides of the clamping device respectively and used for simulating the pulling-out action of a suture after puncture of a suture needle in the manual suture process. The thread pulling mechanism controls a thread pulling rod to alternately pull a thread left and right to ensure that the thread is always in a tensioning state in the single-thread sewing process; the needle and thread storage mechanism ...

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Номер записи: 14
31-08-2021 дата публикации

Patient dress for chest drainage

Номер: CN214071909U
Автор: XU CHIYU, SUN YI, LIU SISI, 徐赤宇, 孙夷, 刘思思
Принадлежит: CHONGQING MYLIKE PLASTIC SURGERY HOSPITAL CO LTD, CHONGQING MYLIKE PLASTIC SURGERY HOSPITAL CO., LTD., 重庆美莱整形美容医院有限公司

The utility model belongs to the field of medical clothes, and relates to a chest drainage patient dress which comprises a dress body, at least one containing bag used for fixing a drainage bag is arranged on the dress body, and an opening communicated with the inside of the dress body is formed in the containing bag. At least one fixing ring is further arranged at the position, higher than the opening, in the clothes body; through the arrangement of the placing bag and the fixing ring structure, the drainage bag and the drainage tube are fixed and limited, so that a patient can conveniently get out of bed to move after an operation, and meanwhile, the drainage bag is also convenient to replace.

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Номер записи: 15
09-05-2023 дата публикации

Stirring drum blade follow-up heat treatment device

Номер: CN116083704A
Автор: JIANG SHENGQIANG, LIU JING, CAO GUODONG, LIU JINGANG, LIU SISI
Принадлежит:

The invention relates to the field of concrete mixing and transporting devices, and mainly comprises a mixing drum device and a heating and cooling device, a rotary motion is given to a mixing drum in the working process, and the rotary motion enables the heating and cooling device to move along the track of the top end of a blade, so that the purpose of carrying out heat treatment on the top of a welded spiral mixing blade in the drum is achieved. The method is low in design cost and easy and convenient to operate, the abrasion resistance of the stirring blade is improved, and meanwhile the problem that the blade cracks in the process that the stirring blade is subjected to heat treatment and then welded is solved, and some problems that heat treatment can only be conducted by depending on a three-dimensional track of the blade are solved.

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Номер записи: 16
08-08-2023 дата публикации

Vegetable and morchella esculenta crop rotation method

Номер: CN116548246A
Автор: TU JIA, LIU SISI, PENG CHAO, XIAO JINGJING, XIAO ZHIHONG, LEE CHANG-JU, JI YUENA, LI LI
Принадлежит:

The invention discloses a vegetable and morchella esculenta crop rotation method, and relates to the technical field of morchella esculenta planting.The vegetable and morchella esculenta crop rotation method comprises the following steps that S1, a vegetable greenhouse is built, S2, vegetables are planted, S3, cultivated species are produced, S4, cultivated land preparation and planting are conducted, and S5, fertilizer, trace elements and microorganisms are added; the amino acid fertilizer comprises the following components in percentage by mass: 0.2%-0.4% of glutamic acid, 0.1%-0.3% of glycine, 0.2%-0.6% of alanine and 0.1%-1.1% of aspartic acid. The microelement is at least one of boron, zinc, iron, manganese, copper or molybdenum; by means of the crop rotation method of the vegetables and the morchella esculenta, efficient utilization of land is achieved; by adding the fertilizer, the trace elements and the microorganisms and optimizing the proportions of all the components, the optimal ...

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Номер записи: 17
16-05-2023 дата публикации

Method and kit for detecting fungi through multiple quantitative PCR (Polymerase Chain Reaction)

Номер: CN116121439A
Автор: SHAO YANG, LIU JIA, ZHAO MINCHAO, NA CHENGLONG, LIU SISI, CUI YUELI, GUO YAO, JIANG WEN, WU WEIWEI
Принадлежит:

The invention discloses a method for simultaneously identifying fungi by utilizing a multiple quantitative PCR (Polymerase Chain Reaction) technology. Specific primers and probes are designed for four important fungi, namely aspergillus fumigatus, cryptococcus neoformans, pneumocystis yarrowii and rhizomucor minuta, and whether aspergillus fumigatus, cryptococcus neoformans, pneumocystis yarrowii and rhizomucor minuta infection exists in a clinical sample or not is simultaneously identified at a time by utilizing multiple fluorescent quantitative PCR (Polymerase Chain Reaction). The detection period of important fungi is shortened, the detection cost is reduced, and rapid diagnosis of fungal infection is effectively realized.

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Номер записи: 18
09-05-2023 дата публикации

Method for green, safe and efficient recovery of lithium resource and fluorine resource in electrolyte and application thereof

Номер: CN116081654A
Автор: ZHOU WEIDONG, MA LE, LIU SISI
Принадлежит:

The invention discloses a method for green, safe and efficient recovery of a lithium resource and a fluorine resource in an electrolyte and an application thereof. The method comprises the following steps: mixing the electrolyte containing a fluorine-lithium compound with a strong alkali solution; evaporating the obtained mixed solution to remove liquid, fully mixing the obtained solid with water, and carrying out solid-liquid separation to obtain a solid recycle LiF; evaporating the liquid isolate to remove liquid, adding the obtained solid into an organic solvent, fully mixing, carrying out solid-liquid separation, and repeatedly mixing and separating the obtained solid isolate with the organic solvent to obtain a solid recovered substance NaF; the method for assisting in recycling the lithium resource and the fluorine resource in the electrolyte by using the strong base is provided for the first time, the technological process is simple, the recycling cost is low, and the method is suitable ...

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Номер записи: 19
23-06-2023 дата публикации

Blade self-following heat treatment device in mixing drum

Номер: CN116287632A
Автор: JIANG SHENGQIANG, LIU JING, CAO GUODONG, LIU JINGANG, LIU SISI
Принадлежит:

The invention relates to the field of concrete mixing and transporting devices, and mainly comprises a mixing drum device, a control device and a heating and cooling device, in the working process, a rotary motion is given to a mixing drum, meanwhile, an axial motion is given to a power sliding table, and the power sliding table drives the heating and cooling device to move along the track of the top end of a blade. And therefore, the purpose of carrying out heat treatment on the top of the welded spiral stirring blade in the cylinder is achieved. The method is low in design cost and easy and convenient to operate, the abrasion resistance of the stirring blade is improved, and meanwhile the problem that the blade cracks in the process that the stirring blade is subjected to heat treatment and then welded is solved, and some problems that heat treatment can only be conducted by depending on a three-dimensional track of the blade are solved.

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Номер записи: 20
04-07-2023 дата публикации

Application of mNGS in distinguishing infectious pleural effusion and malignant pleural effusion

Номер: CN116377057A
Автор: CHE NANYING, SHAO YANG, LIU JIA, ZHAO MINCHAO, NA CHENGLONG, LIU SISI, CUI YUELI, WU WEIWEI, JIANG WEN, ZHU MIAO
Принадлежит:

The invention discloses application of an mNGS technology in distinguishing infectious pleural effusion and malignant pleural effusion, and belongs to the technical field of molecular biomedicine. The mNGS detection technology disclosed by the invention comprises the following steps: extracting nucleic acid in pleural effusion, constructing a library, sequencing on a machine, analyzing CNV and constructing a CNV-GBM model. The mNGS technology can be used for distinguishing infectious pleural effusion patients and malignant pleural effusion patients, the sensitivity is 54.1%, the specificity is 80.8%, and the AUC is 0.851.

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Номер записи: 21
25-08-2023 дата публикации

Quantum homomorphic encryption-based delegation calculation method

Номер: CN116647325A
Автор: FENG YANYAN, GUO ZICHENG, LIU SISI, LI YAN, LI JIE
Принадлежит:

The invention discloses a delegation calculation method based on quantum homomorphic encryption, which comprises the following steps: a client determines data information needing to be encrypted, encodes the data information onto photons and encodes the photons by adopting a bose sampling mode to obtain sequence state data; the client side generates a secret key, encrypts sequence state data and sends the encrypted sequence state data to the server side; the server side evaluates and calculates the received data and sends a result to the client side; and the client decrypts the calculation result to complete the entrusted calculation based on quantum homomorphic encryption. According to the method, the data of the client can be processed in a ciphertext mode, the server carries out calculation processing on the data on the basis of not decrypting the ciphertext, and after calculation is completed, the client can decrypt the calculated and processed data again to obtain a calculation result ...

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Номер записи: 22
28-04-2023 дата публикации

Primer probe group, kit and detection method for detecting pathogenic bacteria through multiple qPCR (quantitative polymerase chain reaction)

Номер: CN116024371A
Автор: SHAO YANG, LIU JIA, ZHAO MINCHAO, NA CHENGLONG, LIU SISI, CUI YUELI, GUO YAO, WU WEIWEI, JIANG WEN
Принадлежит:

The invention provides a multiplex PCR primer, a probe and a detection method for detecting clinical common pathogenic bacteria. Gene sequences of clinically common pathogenic bacteria aspergillus fumigatus, staphylococcus aureus, mycobacterium tuberculosis and mycobacterium abscessus are analyzed and compared, detection primers and probes of fluorescent PCR are designed, and whether a clinical sample is infected by the four pathogenic bacteria or not is simultaneously identified at one time. According to the detection method, the original detection workload is simplified, the detection time is shortened, meanwhile, a etiological basis is provided for clinical diagnosis and treatment, and an important guiding effect is achieved for clinically and specifically selecting antibiotics for use.

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Номер записи: 23
02-05-2023 дата публикации

Targeted HPV-based NGS detection method and kit for minimal residual lesions after treatment of cervical cancer patients

Номер: CN116042920A
Автор: LIU SISI, SHAO YANG, JIANG WEN, WU XUE, NA CHENGLONG, HE PENG, YANG SHANSHAN, ZHENG LIJUAN
Принадлежит:

The invention belongs to the field of targeted next-generation sequencing, and particularly relates to a next-generation sequencing probe set for detecting HPV based on high-throughput sequencing and a method of the next-generation sequencing probe set. The method is especially suitable for detecting the low-abundance HPV sequence contained in the plasma of a treated cervical cancer patient. The target area can be better captured and covered, and enough read data information on the target area is obtained, so that the MRD and treatment prognosis of the target area are evaluated.

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Номер записи: 24
29-08-2023 дата публикации

Leukemia FLT3 mutation detection primer group and detection device

Номер: CN116656817A
Автор: SHAO YANG, HAN XUE, JIANG YA, LIU SISI, NA CHENGLONG, XI YING, WU YUANYUAN, ZHU LIUQING, HE PENG
Принадлежит:

The invention belongs to the technical field of molecular biology, and particularly relates to a kit for detecting tandem repeat mutation and tyrosine kinase structural domain mutation in a leukemia FLT3 gene based on a fluorescent PCR capillary electrophoresis method. The kit is especially suitable for simultaneously detecting two low-abundance mutations in whole blood or bone marrow samples of leukemia patients.

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Номер записи: 25
02-05-2023 дата публикации

Malignant pulmonary nodule screening gene marker, screening model construction method and detection device

Номер: CN116052768A
Автор: SHAO YANG, WU XUE, BAO HUA, LIU RUI, WU SHUYU, WU MIN, YANG SHANSHAN, LIU SISI, ZHENG LIJUAN
Принадлежит:

The invention provides a malignant pulmonary nodule screening gene marker, a malignant pulmonary nodule screening model construction method and a malignant pulmonary nodule screening detection device, which are characterized in that a high-throughput sequencing result is imaged to show a 16bp tumor new short sequence of high-risk pulmonary nodule benign and malignant difference DNA, and the model is constructed by utilizing automatic machine learning; benign and malignant pulmonary nodules with high risk in imaging are predicted, noninvasive accurate diagnosis of malignant pulmonary nodules is realized, and unnecessary benign pulmonary nodule resection operations are reduced.

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Номер записи: 26
23-06-2023 дата публикации

Method for synthesizing amide through photocatalysis of aldehyde

Номер: CN116283640A
Автор: LIU RUKUAN, DENG LANQING, LIU SISI, ZHU LIANGDI, LI ZEMU, XIAO ZHIHONG, XIAO MENGWU
Принадлежит:

The invention relates to the technical field of organic synthesis, in particular to a method for synthesizing amide through photocatalysis of aldehyde. The preparation method comprises the following steps: mixing aldehyde with a solvent, sequentially adding a secondary amine compound, a catalyst and alkali, carrying out a stirring reaction under an oxygen-containing atmosphere and an illumination condition, and separating to obtain an amide compound, according to the invention, the reaction is carried out in the air atmosphere at room temperature and normal pressure under the illumination condition, the reaction condition is mild, the raw material source is wide, the operation is simple and convenient, the cost is low, the atom economy and environmental friendliness are higher, and large-scale production is easy.

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Номер записи: 27
07-07-2023 дата публикации

Behavior subject association analysis method, system, device and medium

Номер: CN116405294A
Автор: LU SHIDA, JIN LINGLI, YAO YIFAN, ZHANG LISHOU, LIU SISI, ZHAO CHUAN, WANG HUAN, CHEN YUMING, JI FENFEN, CHEN JIEQUAN
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The invention belongs to the technical field of communication networks, and discloses a behavior subject association analysis method, system and device and a medium, and the behavior subject association analysis method comprises the steps: obtaining HTTP communication data to be subjected to behavior subject association analysis; based on the HTTP communication data, active behaviors of behavior subjects are obtained; obtaining a direct association item and an indirect association item based on the active behavior of the behavior subject; and performing association analysis on the active behavior of the behavior subject based on the quintuple, the direct association item and the indirect association item to obtain a behavior subject association analysis result. According to the behavior subject association analysis method provided by the invention, the behavior subject of each piece of behavior data in the HTTP communication data can be determined, and the method can be used for tracing ...

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Номер записи: 28