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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 2. Отображено 2.
07-04-2023 дата публикации

Targeted APLNR protein palmitoylation modified polypeptide and application thereof in cancer pain treatment

Номер: CN115920057A
Автор: FANG ZHIYOU, FAN XIAOQING, CHEN XUERAN, SUN SULING, GONG MEITING, ZHANG SIYU, YU HUIHAN
Принадлежит:

The invention discloses a targeted APLNR protein palmitoylation modified polypeptide and application of the targeted APLNR protein palmitoylation modified polypeptide in cancer pain treatment, and particularly relates to application of APLNR protein and a palmitoylation modified site of the APLNR protein in relieving morphine drug resistance in cancer pain treatment. The invention finds that APLNR palmitoylation modification is one of important response factors for occurrence of neuropathic cancer pain, the polypeptide targeted to APLNR protein palmitoylation modification is developed by taking the APLNR protein as a target spot, and the polypeptide is combined with morphine to treat cancer pain, so that cancer pain can be effectively reduced, morphine tolerance can be relieved, and the application of the APLNR protein palmitoylation modification in neuropathic cancer pain treatment is facilitated. A new strategy is provided for clinically treating cancer pain and relieving morphine tolerance ...

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Номер записи: 1
23-06-2023 дата публикации

Green extraction method of polyphenol compounds in olive oil

Номер: CN116298014A
Автор: LI XUE, WANG WEI, ZHANG YU, HU GUIXIAN, WANG JUNHONG, SUN SULING, LIANG FENG
Принадлежит:

The invention belongs to the field of pretreatment of green samples, and particularly relates to a method for green and rapid extraction of polyphenol compounds in olive oil based on a water-based eutectic solvent-liquid-liquid microextraction technology. The invention discloses a green extraction method of polyphenol compounds in olive oil, which comprises the following steps: mixing a hydrogen bond acceptor reagent with water, and carrying out ultrasonic treatment to obtain a water-based eutectic solvent; olive oil, normal hexane and a water-based eutectic solvent are subjected to vortex mixing, then ultrasonic treatment and centrifugation are conducted, and after centrifugation, an oil layer located on the upper layer and a eutectic solvent layer located on the lower layer are divided; taking the eutectic solvent layer as an extracting solution; the extracting solution contains a polyphenol compound.

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Номер записи: 2