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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 23. Отображено 23.
27-08-2021 дата публикации

Municipal road rainwater storage pond

Номер: CN214061915U

The municipal road rainwater regulation and storage pond comprises a pond body with an opening in the upper end, the pond body is cylindrical, a pond cover used for covering the opening in the upper end of the pond body is arranged on the pond body, and a cleaning mechanism used for cleaning the inner wall of the pond body is arranged on the pond cover. The cleaning mechanism comprises a rotating shaft and a driving motor, the rotating shaft is detachably connected to the tank cover, the driving motor drives the rotating shaft to rotate, and a horizontally arranged stirring paddle is connected to the rotating shaft; the end part of the stirring paddle is detachably connected with a material scraping plate which is vertically arranged, can move towards the inner wall of the tank body and is always propped against the inner wall of the tank body. The sewage treatment tank has the effect of conveniently cleaning sludge with relatively high adsorbability on the inner wall of the tank body.

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04-11-2010 дата публикации

DUAL INTERFACE MEMORY DEVICE AND ELECTRONIC APPARATUS USING SAME

Номер: WO2010124483A1
Автор: YANG, Junliang, ZHONG, Wei
Принадлежит:

Disclosed is a dual interface memory device, which includes: a memory unit, a coupling unit connected to the memory unit, and an input/output (I/O) interface connected to the memory unit. The I/O interface enables the dual interface memory device to communicate with external devices. The memory device can communicate with readers via non-contact mode and transmit data and information via the I/O interface, largely increasing the scope of application of the memory device.

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06-06-2023 дата публикации

Steel bar sawing robot based on trepanning optimization and machining method

Номер: CN116213823A
Принадлежит:

The invention relates to the technical field of steel bar machining, in particular to a steel bar sawing robot based on trepanning optimization and a machining method. The automatic bar sawing machine comprises an automatic bar feeding frame, a sawing feeding roller way, an excess material turning mechanism, a fixed-length feeding mechanism, an automatic sawing machine, a sawing discharging roller way and an electric control device. According to a material list provided by a sample turning system, fixed-length raw materials of bar steel bars can be provided for a construction site, and the steel bars of different specifications, different numbers and different sizes are sorted in advance according to component packages; and wrong machining and missing machining can be effectively avoided, the empty rate of transferred vehicles is reduced, and the material transferring cost is saved.

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07-04-2022 дата публикации

APPLICATION INTERFACE LAYOUT METHOD AND ELECTRONIC DEVICE

Номер: WO2022068594A1
Принадлежит:

An application interface layout method and an electronic device, relating to the technical field of electronics, and being capable of reducing the workload of an application developer for developing and maintaining a layout file of an application interface. The method specifically comprises: a developer provides, in a layout file of an application, a layout container having an adaptive layout capability, wherein the adaptive layout capability comprises at least one of an extension capability, a proportion capability, an equal division capability, a wrapping capability, a hiding capability, a stretching capability, or a scaling capability. Thus, when the electronic device runs the application, the sizes and positions of child controls in the layout container on a display interface are laid out according to a screen parameter of the electronic device and the adaptive layout capability of the layout container in the layout file.

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25-04-2023 дата публикации

Application of quinazoline compound in overcoming osimertinib drug resistance

Номер: CN115998743A
Автор: ZHONG WEI
Принадлежит:

The invention provides application of a quinazoline compound in overcoming osimertinib drug resistance, and the quinazoline compound comprises at least one of a quinazoline derivative as shown in a formula I, a salt of the quinazoline derivative, a prodrug, a prodrug salt, a solvate, a hydrate and a polymorphic substance of the quinazoline derivative. Compared with the prior art, the quinazoline derivative disclosed by the invention has the following beneficial effects: 1, the quinazoline derivative (I) and the pharmaceutical salt thereof can overcome the drug resistance of osimertinib, especially the drug resistance caused by EGFR C797S, L792H, Del19/C797S double mutation or L858R/C797S double mutation, and inhibit tumor growth; 2, the quinazoline derivative (I) and the pharmaceutical salt thereof disclosed by the invention can be used for effectively treating non-small cell lung cancer which is invalid after osimertinib treatment, including non-small cell lung cancer nerve center metastasis ...

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17-10-2019 дата публикации

USAGE OF QUINAZOLINE COMPOUND AND AVASTIN IN PREPRARING COMBINED DISEASE-PREVENTING MEDICINE

Номер: WO2019196620A1
Принадлежит:

Provided in the present invention is a usage of a quinazoline compound and avastin in preparing a combined disease-preventing medicine. Said quinazoline compound comprises the quinazoline derivative as shown in Formula I and at least one of a salt thereof, a prodrug, a prodrug salt, a solvate, a hydrate, and polycrystalline. In comparing (I) to prior art, the present invention has the following beneficial effects: 1. said quinazoline derivative (I) and the composition of the pharmaceutical salts thereof and avastin in the present invention have unexpected synergistic effects, and has better treatment effects than a single medicine for diseases such as cancer, cancer brain metastasis, cancer meningeal metastases, brain cancer, and central nervous system diseases; 2. said quinazoline derivative (I) and the composition of the pharmaceutical salts thereof and avastin in the present invention may extend the time needed for cancer cells to generate medical resistance, and may thus extend progression-free ...

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17-10-2019 дата публикации

USE OF QUINAZOLINE COMPOUND IN DRUG FOR TREATING CANCERS WITH EGFRV3 ACTIVATING MUTATION

Номер: WO2019196621A1
Принадлежит:

Provided is the use of a quinazoline compound in a drug for treating cancers with an EGFRv3 activating mutation. The quinazoline compound includes a quinazoline derivative of the structure of formula I (I) and a salt, prodrug, prodrug salt, solvate and hydrate thereof or a polymorph thereof. Compared to the prior art, the present invention has the following beneficial effects: 1) the quinazoline derivative (I) of the present invention and the pharmaceutical salt thereof have an unexpected efficacy on cancers mediated by EGFRv3 mutations, and have a better efficacy than that on similar cancers without this mutation, for example, cancers with EGFRV3 mutations, metastatic brain cancer, metastatic meningeal cancer, brain cancer and central nervous diseases, etc.; and 2) the quinazoline derivative (I) of the present invention and the pharmaceutical salt thereof can increase the effectiveness on similar cancers for EGFRv3 mutations, and can be selected for cancer patients with EGFRv3 mutations ...

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16-03-2017 дата публикации

METHOD OF DESIGNING BOX-TYPE ENERGY-DISSIPATING SECTION OF BOX-TYPE ENERGY-DISSIPATING MUDFLOW DIVERSION FLUME, AND APPLICATION

Номер: WO2017041315A1
Принадлежит:

A method of designing a box-type energy-dissipating section of a box-type energy-dissipating mudflow diversion flume. Firstly, the longitudinal gradient J of the flume and the roughness coefficient n0 of a fully-lined flume bottom (1) are determined. Then, the parameters of the box-type energy-dissipating section are set, and related parameters are substituted into a formula for calculation, so that the overall roughness coefficient n of the flume is obtained. Further, the flow velocity of the mudflow is calculated by means of the Manning formula. Finally, the flow velocity of the mudflow is compared with the non-scouring and non-silting velocity allowed by the flume, and the design value of the box-type energy-dissipating section is obtained through final optimization. The method factors in the longitudinal gradient J of the flume, the length L of the box-type energy-dissipating section, the width b of the box-type energy-dissipating section, and the average diameter D of filler stones ...

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15-06-2016 дата публикации

Revetment brick

Номер: CN0205314113U
Автор: ZHONG WEI, KONG JIMING, CUI YUN
Принадлежит:

... 本实用新型涉及一种砖,具体为护坡砖,砖体中间有垂直上下通透的空腔,砖体的四个侧壁分别为前侧壁、后侧壁和两个相对的侧壁,砖体顶面为平面,砖体底面为斜面,前侧壁的下边缘为斜面较低的一边,所述的两个相对的侧壁,其中一侧壁上有垂直的凹槽,另一侧的侧壁上有对应的凸起,凸起插入相邻护坡砖的凹槽;所述的后侧壁下边缘有垂直向下的卡板。本实用新型提供的护坡砖放置在坡地上,后侧壁朝向破顶一侧,将前侧壁的下边缘插入坡面土壤内,同时后侧壁的卡板也嵌入到土壤中,从上下两处将砖体固定在坡面上,砖体不易滑落,起到有效的护坡作用。 ...

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17-10-2019 дата публикации

QUINAZOLINE DERIVATIVE SALT-FORM CRYSTAL FORM, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Номер: WO2019196619A1
Принадлежит:

Disclosed are a quinazoline derivative salt-form crystal form, and a preparation method therefor and an application thereof. The quinazoline derivative salt-form crystal form is specifically hydrochloride crystal forms A, B, C, D, F, H, I, a sulfate crystal form A, a maleate crystal form A, a succinate crystal form A, a adipate crystal form A, a glycolate crystal form A, a malate crystal form A, a fumarate crystal form A, benzene sulfonate crystal forms A, B, C, a benzoate crystal form A, a hippurate crystal form A, and an oxalate crystal form A of a quinazoline derivative represented by formula (I). The salt-form crystal forms provided in the present invention have good stability, can be applied to drugs for treating non-small cell lung cancer, meningeal metastases, primary brain cancer, brain glioma, or the like, have better bioavailability, and have great significance to further studies about the efficacy of such solid drugs.

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24-02-2011 дата публикации

PACKING METHOD FOR BI-INTERFACE SMART CARD

Номер: WO2011020244A1
Автор: YANG, Junliang, ZHONG, Wei
Принадлежит:

A packing method for bi-interface smart card involves the following steps: securing the module(8) of the bi-interface smart card to the card base(7) of the bi-interface smart card; welding the starting joint of the antenna(9) with one of the welding points(3); burying the antenna;welding the end joint of the antenna with the other welding point; infusing glue or filler in the welding through holes(5); finally laminating the welding layer with printing layer (11).

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17-05-2018 дата публикации

SUBSTITUTED QUINAZOLINE COMPOUND HAVING BLOOD-BRAIN BARRIER PENETRATION CAPABILITY

Номер: WO2018086446A1
Автор: ZHONG, Wei
Принадлежит:

Disclosed is a substituted quinazoline compound having blood-brain barrier penetration capability. The structural formula of the compound is as represented by formula (I). The substituted quinazoline compound of the present invention, and a derivative and a pharmaceutical salt thereof have unexpected blood-brain barrier penetration capability, and pharmaceutical characteristics which enable them to serve as protein kinase inhibitors. They are particularly used for medical situations mediated by some activated and mutated forms of an epidermal growth factor receptor, and can be used for treating or preventing disorders associated with abnormal protein kinase activity, such as cancer, brain metastasis, meningeal metastasis, and central nervous diseases.

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19-08-2010 дата публикации

DUAL INTERFACE INTELLIGENT CARD AND ITS COMMUNICATION METHOD, AND CORRESPONDING POSITIONING SYSTEM AND METHOD

Номер: WO2010091560A1
Принадлежит:

The invention discloses a dual interface intelligent card and its communication method, and corresponding positioning system and method. The invention adopts ZigBee wireless network node unit to make the intelligent card have the ability to organize network by self, and applying the card to different electronic devices enables fast combining mobile communications field with intelligent family field. The dual interface intelligent card comprises: a contact intelligent card unit for exchanging data with the electronic device by the mode of contact exchanging data; a ZigBee wireless network node unit for receiving or sending data based on ZigBee protocol; a storage unit; a micro processing unit for respectively electrically connecting with the contact intelligent card unit, the ZigBee wireless network node unit and the storage unit to manage and access these units, and maintain the data transfer among these units.

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28-10-2010 дата публикации

ELECTRONIC LABEL PACKAGING AND ITS MANUFACTURING METHOD

Номер: WO2010121454A1
Автор: YANG, Junliang, ZHONG, Wei
Принадлежит:

A kind of electronic label packaging includes: an electronic label wafer, packaging pins and a base board laid on the electronic label wafer and the packaging pins, wherein the packaging pins are connecting to the electronic label wafer electrically, and the electronic label wafer, packaging pins and the base board are packaged in the packing fillings together. The manufacturing method of the electronic label packaging includes: making wafer set, on which making some electronic label wafers arranged in matrix; cutting the wafer set to get a single electronic label wafer; picking-up the electrical label wafer and put it on a base board directly; making packaging pins and put them on the base board; connecting the packaging pins to the electronic label wafer electrically; encapsulating the electronic label wafer, the base board and the packaging pins by packing fillings.

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17-10-2019 дата публикации

5-SUBSTITUTED DIFLUOROPIPERIDINE COMPOUND CAPABLE OF PASSING THROUGH BLOOD-BRAIN BARRIER

Номер: WO2019196622A1
Автор: ZHONG, Wei
Принадлежит:

Disclosed is a 5-substituted difluoropiperidine compound capable of passing through a blood-brain barrier. The structural formula of the compound is formula (I). The 5-substituted difluoropiperidine compound, a derivative, and a pharmaceutically acceptable salt thereof have an unexpected capability of passing through a blood-brain barrier, and a medicinal property of serving as a protein kinase inhibitor, especially for medical situations mediated by a vascular endothelial cell growth factor receptor 2 or SRC kinase family (FYN), and can be used for treating or preventing disorders associated with abnormal protein kinase activity, such as cancers and cancer brain metastasis, primary brain cancers such as brain glioma, malignant brain glioma, cancer meningeal metastasis, Alzheimer's disease, and nerve center diseases.

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05-05-2023 дата публикации

Modularized intelligent reinforcing steel bar processing production line and process based on Internet of Things

Номер: CN116060540A
Принадлежит:

The invention relates to the technical field of house building project reinforcing steel bar machining, in particular to a modularized intelligent reinforcing steel bar machining production line and technology based on the Internet of Things. Based on the research and development thought that equipment moves around steel bars, and information flows along with the steel bars, the modularized intelligent steel bar machining technology based on the Internet of Things is innovatively provided, and meanwhile a matched steel bar machining production line is provided; the reinforcing steel bar machining production line comprises high-performance reinforcing steel bar sawing, thread rolling and sorting equipment based on an unmanned factory and high-flexibility multifunctional bar-line reinforcing steel bar integrated bending equipment based on a construction site, the reinforcing steel bar material loss can be greatly reduced, the reinforcing steel bar machining efficiency is remarkably improved ...

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06-07-2016 дата публикации

Ecological bank protection brick

Номер: CN0205369161U
Автор: ZHONG WEI, LI XIUZHEN, CUI YUN
Принадлежит:

... 本实用新型涉及一种砖,具体为生态护坡砖,砖体有上下通透的植物种植孔,砖体的四个侧壁分别为前侧壁、后侧壁和两个相对的侧壁,砖体顶面为平面,前侧壁比后侧壁高,砖体底面为多层台阶状,砖体还有两个上下通透的插孔,分别为靠近前侧壁的前插孔、靠近后侧壁的后插孔。本实用新型提供的生态护坡砖,通过多重措施防止砖体滑落。 ...

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06-07-2016 дата публикации

Automatic pin is riveted into machine

Номер: CN0205363198U
Автор: ZHONG WEI
Принадлежит:

... 本实用新型涉及一种自动销钉铆入机,属于机械加工设备领域。其包括电气系统、机械系统和PLC控制系统,电气系统包括工装伺服系统和运动部件控制系统,机械系统包括机架、内置控制柜、启动按钮、废料吸收器和触控屏,机架的平台上横向固定有方直线导轨,沿方直线导轨从右到左依次固定打孔装置、销钉上料装置和铆接装置;方直线导轨上还可滑动地连接有工装滑板;工装伺服系统和运动部件控制系统与PLC控制系统配合控制实现本实用新型的自动化操作。本实用新型实现了销钉铆入过程的自动化,同时又保证了此过程中每个步骤的精准度,大大提高了产品的合格率和生产效率,同时减小了人工工作量,减小了人工操作难度,降低了生产成本。 ...

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05-05-2023 дата публикации

Slope protection for ecological reconstruction of rock-soil side slope

Номер: CN116065608A
Принадлежит:

The invention discloses a rock-soil side slope ecological reconstruction protection slope which comprises a rock-soil layer, a soil culture layer is installed at the top of the rock-soil layer, soil fixing rings are installed at the top of the soil culture layer in a penetrating mode, installation nails are installed at the top of the soil culture layer in a penetrating mode, and the installation nails are located between the two soil fixing rings. A buried column is mounted at the top of the soil culture layer in a penetrating manner, the buried column is located in front of the soil fixing ring, and the bottom of the buried column is buried into the rock-soil layer; fixing screws are installed on the inclined face of the soil culture layer in a penetrating mode, and the bottom ends of the fixing screws are inserted into the rock-soil layer. According to the device, the soil fixing ring is installed and inserted into the inner side of the soil culture layer through the embedding pipe, ...

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28-04-2023 дата публикации

Multifunctional bar and wire bending machining equipment and machining method based on visual recognition

Номер: CN116020958A
Принадлежит:

The invention relates to the technical field of steel bar bending machining, in particular to multifunctional bar and wire bending machining equipment based on visual recognition and a machining method. The steel bar bending machine can meet the bending machining requirements of steel bars of various specifications and shapes, the machining efficiency is high, the quality and precision are guaranteed, and machining information is traceable; advanced technologies and equipment such as a visual identification technology and a reinforcing steel bar grabbing manipulator are introduced, intelligent bending of bars and reinforcing steel bars after visual identification on a construction project site can be achieved, and machining procedures such as straightening, bending, hoop bending and cutting-off can be automatically carried out after wire rod equipment receives a task; and steel bars with different shapes, such as stirrups, draw hooks and long plate ribs, can be processed according to construction ...

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02-05-2023 дата публикации

Substituted 1-(3, 3-difluoropiperidin-4-yl)-imidazo [4, 5-c] quinolin-2-one compounds having blood-brain barrier penetrating power

Номер: CN116056698A
Автор: ZHONG WEI
Принадлежит:

The present invention relates to substituted 1-(3, 3-difluoropiperidine-4-yl)-8-(pyridin-3-yl)-1, 3-dihydro-2H-imidazo [4, 5-c] quinolin-2-one compounds having the ability to pass through the blood brain barrier, and to a method for preparing the same. The substituted 1-(3, 3-difluoropiperidine-4-yl)-8-(pyridine-3-yl)-1, 3-dihydro-2H-imidazo [4, 5-c] quinoline-2-one compound has a structural formula shown in a formula (I). The substituted 1-(3, 3-difluoropiperidine-4-yl)-8-(pyridine-3-yl)-1, 3-dihydro-2H-imidazo [4, 5-c] quinoline-2-one compound, the derivative and the pharmaceutically acceptable salt thereof have the capability of penetrating through a blood-brain barrier, and can be used as a characteristic medicine of a protein kinase inhibitor. In particular, they act as characteristic drugs for proteins expressed by ataxia-telangiectasia mutant kinase (ATM) and can be used as monotherapy or in combination with other therapies for the treatment or prevention of disorders associated ...

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22-06-2016 дата публикации

Automatic hot jacket kludge

Номер: CN0205325117U
Автор: ZHONG WEI
Принадлежит:

... 本实用新型涉及一种自动热套组装机,属于机械加工设备领域。其包括电气系统、机械系统和PLC控制系统;所述电气系统包括工装伺服系统、加热伺服系统和运动部件控制系统,且电气系统受控于PLC控制系统;所述机械系统包括机架和安装在机架上的内置控制柜、工装分割装置、触控装置和高频感应加热装置。由电气系统、机械系统和PLC控制系统三者配合完成自动热套工装工艺。本实用新型用高频感应加热,避免了间接加热带来的资源浪费和安全隐患;其次大大提高了整个工装过程的自动化程度,也提高了产品的合格率和生产效率,减少了人工耗费。 ...

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11-08-2023 дата публикации

Prestressed anchor groove structure

Номер: CN116575315A
Принадлежит:

The invention discloses a pre-stressed anchor groove structure which comprises an anchor groove fence steel plate, a plurality of in-groove anchor buckle steel plates, a plurality of out-groove anchor buckle steel plates, a plurality of in-groove anchor bolts, a plurality of out-groove anchor bolts, anchor groove transverse ring ribs, anchor groove longitudinal ring ribs and out-groove steel bar connectors. The multiple in-groove anchor bolts are connected with the upper-layer in-groove anchor buckle steel plate and the lower-layer in-groove anchor buckle steel plate, the multiple out-groove anchor buckle steel plates are welded along the periphery of the anchor groove fence steel plate and distributed in the upper-layer and the lower-layer mode, the multiple out-groove anchor bolts are connected with the upper-layer out-groove anchor buckle steel plate and the lower-layer out-groove anchor buckle steel plate, and the anchor groove transverse ring ribs and the anchor groove longitudinal ...

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