INORGANIC SALT-CONTAINING LAYERED DISSOLVING MICRO-NEEDLE CONTAINING INORGANIC SALT

An inorganic salt-containing layered dissolving micro-needle containing inorganic salt, and a preparation method therefor. The inorganic salt-containing layered dissolving micro-needle comprises a substrate, a needle body on the substrate, and a needle tip on the needle body. The needle tip is made by mixing an inorganic salt solution, a stabilizer, a film-forming water-soluble polymer material, and a bioactive component; the needle body and the substrate are made of the film-forming water-soluble polymer material, or the film-forming water-soluble polymer material and the stabilizer. The inorganic salt-containing layered dissolving micro-needle containing inorganic salt improves the formability of a needle tip of an inorganic salt-containing micro-needle and improves stability of a bioactive component.

泡罩包装盒

PLUM-BLOSSOM NEEDLE CUPPING DEVICE HAVING ACCURATE BLOODLETTING FUNCTION

A plum-blossom needle cupping device comprises: a cup (1) and a plum-blossom needle bloodletting pen (2) arranged at the top center of the cup (1); and a negative-pressure bloodletting gun (3) applying a vacuum to the cup (1) via the plum-blossom needle bloodletting pen (2). The cup (1) is connected, in a slidable and sealed manner, to the plum-blossom needle bloodletting pen (2). The negative-pressure bloodletting gun (3) drives the plum-blossom needle bloodletting pen (2) to move vertically. The cupping device is utilized to realize functions of a controlled needling depth, formation of a negative pressure immediately after cupping and needling, and automatic blood stasis removal.

IMPLANTABLE SUSTAINED-RELEASE MICRONEEDLE PATCH AND PREPARATION METHOD THEREFOR

An implantable sustained-release microneedle patch and a preparation method therefor. The implantable sustained-release microneedle comprises a needle tip, a needle body, and a base. The needle tip comprises a needle tip center layer and a needle tip outer layer. The needle tip center layer is formed of a matrix comprising a biodegradable water-insoluble polymer material. The needle tip outer layer, the needle body and the base are formed of a matrix comprising a water-soluble polymer material. The microneedle patch comprises the microneedle, and absorbs moisture of skin when the microneedle acts on skin, so that the base and the needle body are quickly separated from the needle tip within 0.5-2h. After the base is removed, the needle tip will be left in skin, and the user does not need the patch sticking for a long time to ensure long-term release of a drug in the body.

QUICK IMPLANTABLE SLOW-RELEASE MICRONEEDLE PATCH AND PREPARATION METHOD THEREFOR

A quick implantable slow-release microneedle, comprising a needle tip, a middle layer, a needle body, and a base. The needle tip is prepared from a biodegradable and water-insoluble macromolecular material matrix; the middle layer is prepared from a hydrophilic material matrix; and the needle body and the base are prepared from a macromolecular material matrix having biocompatibility. A preparation method for the microneedle. A quick implantable slow-release microneedle patch, comprising a microneedle array and a backing constituted by the microneedles.

GLP-1 receptor agonist drug microneedle composition, microneedle prepared from GLP-1 receptor agonist drug microneedle composition as well as preparation method and application of GLP-1 receptor agonist drug microneedle composition

The invention discloses a GLP-1 receptor agonist drug microneedle composition. The composition comprises a GLP-1 receptor agonist drug, a GLP-1 receptor agonist drug, a GLP-1 receptor agonist drug and a GLP-1 receptor agonist drug, the protective agent is selected from zinc-containing pharmaceutical compounds; and a microneedle excipient; wherein the mass ratio of the protective agent to the GLP-1 receptor stimulant drug is (0.1: 1)-(2: 1). When the composition provided by the invention is used in the microneedle, the problems of high GLP-1 receptor stimulant medicine transportation cost, inconvenience in administration, strict storage conditions and the like can be solved. The invention also discloses a microneedle prepared from the composition as well as a preparation method and application of the microneedle.

Nano-crystallization method of cannabidiol, nano-crystallized cannabidiol suspension prepared by nano-crystallization method and application of nano-crystallized cannabidiol suspension

The invention discloses a nano-crystallization method of cannabidiol, a nano-crystallized cannabidiol suspension prepared by the nano-crystallization method and application of the nano-crystallized cannabidiol suspension. The nano-crystallization method of cannabidiol comprises the following steps: dissolving cannabidiol in a good solvent to obtain a cannabidiol-good solvent solution; adding the cannabidiol-good solvent solution into an aqueous solution of a stabilizer, carrying out ultrasonic treatment, and carrying out rotary evaporation to remove the good solvent, so as to obtain a nanocrystallized cannabidiol suspension; wherein the stabilizing agent is selected from one or more of poloxamer, Tween, polyoxyethylene alkyl ether, polyvinylpyrrolidone, hydroxypropyl methyl cellulose and chitosan. According to the nanocrystallization method, the particle size of the insoluble drug cannabidiol is reduced through the insoluble drug nanocrystallization technology, the cannabidiol nanosuspension ...

Bus stop borad that can go up and down

... 本实用新型公开了一种能升降的公交站牌，包括底座、支撑杆、站牌本体和太阳能发电装置；所述底座设置在该能升降的公交站牌的下部，底座固定在地面上；所述底座上部设有控制按钮，控制按钮能控制气压传动装置的运行；所述底座上部还设有支撑杆，支撑杆包括下支撑杆和上支撑杆；所述下支撑杆内部设有气压传动装置；所述上支撑杆连接在下支撑杆内气压传动装置中的气压杆上；所述上支撑杆上部设有站牌本体上部设有立柱，立柱上部设有遮雨棚，遮雨棚上设有太阳能发电装置；本牌本体；所述站牌本体表面设有盲文书写区、触摸屏、LED屏、驱蚊灯和摄像头；所述站实用新型结构简单，使用方便；能将站牌位置降低到合适位置，供乘客观察使用。 ...