04-08-2017 дата публикации
Номер: KR1020170089701A
Принадлежит:
The present invention relates to a zwitterionic temperature sensitive polymer having sol-gel transition characteristics and uses as a biomaterial of the zwitterionic temperature sensitive polymer. A first aspect of the present invention provides a zwitterionic temperature sensitive polymer which is represented by chemical formula 1, Z^1-PAG-Z^2. In chemical formula 1, PAG is polyalkylene glycol; and Z^1 and Z^2 each independently includes a zwitterionic material selected from the group consisting of phosphoryl choline, phosphoryl ethanolamine, phosphoryl serine, sulfobetaine, carboxybetaine, and combinations thereof. The zwitterionic temperature sensitive polymer according to an embodiment of the present invention enables tissues to be regenerated by mixing the zwitterionic temperature sensitive polymer in a sol state with a medicine or cells, injecting the mixture into the body through hypodermic injection or muscular injection, thereby enabling a hydrogel to be instantaneously produced ...
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