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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 17. Отображено 17.
26-10-2017 дата публикации

METHOD FOR CORRECTING MICROALGAE USING RGEN RNP

Номер: WO2017183936A1
Автор: JIN, Eon Seon, BAE, Sang Su, BAEK, Kwang Ryul, KIM, Duk Hyoung, JEONG, Joo Yeon
Принадлежит:

The present invention provides: a method for correcting a microalgae gene without DNA introduction by using a RNA-guided engineered nuclease (RGEN) RNP complex; and a microalgae variant with a corrected gene. The gene correction method according to the present invention has an advantage in that a desired gene can be selectively and accurately corrected without DNA introduction. In addition, the present invention is directed to novel algae with an improved pigment producing ability, and the use of a mutant strain of the present invention can produce carotenoid-based pigments, specifically, xanthophylls, through the consumption of less energy, thus leading to an efficient production of pigments at the industrial level. In addition, the present invention can be applied as a raw material for food, health functional food, and medicine containing pigments. Especially, a procedure of manufacturing the mutant strain is not assumed to be regulated by GMO legislation since DNA fragments are not likely ...

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Номер записи: 1
15-07-2016 дата публикации

ENDONUCLEASE FOR TARGETING BLOOD COAGULATION FACTOR VIII AND USE THEREOF

Номер: KR1020160084958A
Автор: KIM, DONG WOOK, KIM, JIN SOO, PARK, CHUL YONG, KIM, DUK HYOUNG
Принадлежит:

The present invention relates to a method for inducing inversion of normal blood coagulation factor VIII (F8) genes, a method for correcting inversion of blood coagulation factor VIII (F8) genes in which inversion occurs, and inversion-corrected Type A hemophilia patient-derived Induced pluripotent stem cells fabricated by using the same. The method efficiently reproduces inversion of Intron 1 and Intron 22 of F8 genes occupying most part of the causes of severe Type A hemophilia, and thus is useful as a research tool for studying a disease mechanism of Type A hemophilia and for screening a therapeutic agent thereof. In addition, the inversion-corrected Type A hemophilia patient-derived Induced pluripotent stem cells fabricated by the method according to the present invention restores a genotype in which mutation occurs into a wild type-like state not by using a limited method trough normal gene or protein transfer, and thus enable efficient and fundamental therapy for Type A hemophilia ...

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Номер записи: 2
17-10-2018 дата публикации

METHOD FOR CULTIVATING FUNCTIONAL STEVIA ONION USING STEVIA LIQUID AND ONION LIQUID USING STEVIA

Номер: KR101908518B1
Автор: KIM, DEOK HYEONG
Принадлежит: KIM, DEOK HYEONG

The present invention relates to a method for cultivating a functional stevia onion using a stevia liquid and an onion liquid using stevia. The method for cultivating a functional stevia onion can obtain a functional onion with excellent nutrient ingredients by forming a fermented liquefied fertilizer by adding fermented matter using the stevia and spraying the fermented liquefied fertilizer to a leaf surface so that the onion can absorb the onion. According to the present invention, the method for cultivating a functional stevia onion using a stevia liquid includes: a step of harvesting the stevia in August or September by cultivating the stevia and cutting the stevia so that the stevia including the dried leaf and stem are 6cm or less; a step of adding 40 liters of raw rice wine, 20 kg of sugar, 60 kg of onions, 10 kg of EM extract, and 1 kg of the stevia which is dried and cut, into a fermentation container for the liquefied fertilizer and fermenting and ripening the fermentation container ...

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Номер записи: 3
29-10-2015 дата публикации

HEAT EXCHANGING PIPE BURIED IN CAST-IN-PLACE PILE AND CONSTRUCTION METHOD USING SAME

Номер: KR1020150121280A
Автор: CHOI, HANG SEOK, PARK, SANG WOO, KOH, HYUNG SEON, JOO, YONG SUN, JUNG, KYOUNG SIK, MIN, SUN HONG, KIM, DUCK HYOUNG
Принадлежит:

The present invention relates to a protecting cap combined with an iron mesh and a heat exchanging pipe composing a cast-in-place pile of an underground heat exchanging system and a construction method using the same. The protecting cap comprises: a cap body unit having an outer diameter corresponding to the diameter of the cast-in-place pile, and a hollow at the center; an iron mesh hole formed on the cap body unit for allowing the iron mesh to pass through; and a pipe hole formed on the cap body unit for allowing the heat exchanging pipe to pass through. The protecting cap is inserted into the top of the heat exchanging pipe and the iron mesh which have been completely installed. COPYRIGHT KIPO 2016 (AA) Heat exchanging pipe (BB) cast-in-place pile ...

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Номер записи: 4
14-07-2016 дата публикации

ENDONUCLEASE TARGETING BLOOD COAGULATION FACTOR VIII GENE AND COMPOSITION FOR TREATING HEMOPHILIA COMPRISING SAME

Номер: WO2016111546A2
Автор: KIM, Dong Wook, KIM, Jin Soo, PARK, Chul Yong, KIM, Duk Hyoung, KIM, Jung Eun, KWEON, Ji Yeon
Принадлежит:

The present invention provides a method for inducing an inversion of normal blood coagulation factor VIII (F8) gene, a method for correcting an inversion of blood coagulation factor VIII gene in which the inversion has occurred, and a Hemophilia A patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the F8 gene, which is responsible for the majority of severe hemophilia A, and thereby may be effectively used for studying the development mechanism of hemophilia A and as a research tool for screening therapeutic agents. The inversion-corrected induced pluripotent stem cell constructed according the method of the present invention enables an efficient and fundamental treatment for hemophilia A by restoring a genotype in which mutation has occurred to a wild type-like state, without limitation via normal gene or protein delivery.

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Номер записи: 5
14-07-2016 дата публикации

ENDONUCLEASE TARGETING BLOOD COAGULATION FACTOR VIII GENE AND COMPOSITION FOR TREATING HEMOPHILIA COMPRISING SAME

Номер: WO2016111546A3
Автор: KIM, Dong Wook, KIM, Jin Soo, PARK, Chul Yong, KIM, Duk Hyoung, KIM, Jung Eun, KWEON, Ji Yeon
Принадлежит:

The present invention provides a method for inducing an inversion of normal blood coagulation factor VIII (F8) gene, a method for correcting an inversion of blood coagulation factor VIII gene in which the inversion has occurred, and a Hemophilia A patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the F8 gene, which is responsible for the majority of severe hemophilia A, and thereby may be effectively used for studying the development mechanism of hemophilia A and as a research tool for screening therapeutic agents. The inversion-corrected induced pluripotent stem cell constructed according the method of the present invention enables an efficient and fundamental treatment for hemophilia A by restoring a genotype in which mutation has occurred to a wild type-like state, without limitation via normal gene or protein delivery.

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Номер записи: 6
01-11-2017 дата публикации

EDITING METHOD FOR MICROORGANISM USING RGEN RNP

Номер: KR1020170121051A
Автор: JIN, EON SEON, BAE, SANG SU, BAEK, KWANG RYUL, KIM, DUK HYOUNG
Принадлежит:

Provided are a method for editing gene of microorganism without introduction of DNA using a composite of RNA-guided engineered nuclease (RGNE) ribonucleoprotein (RNP), and a gene-edited mutant microorganism. According to the present invention, the gene editing method makes it possible to accurately and selectively edit desired gene without introduction of DNA. COPYRIGHT KIPO 2017 ...

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Номер записи: 7
14-08-2017 дата публикации

WIDTH ADJUSTABLE DISPLAY STAND

Номер: KR1020170092852A
Автор: KIM, DUK HYUNG
Принадлежит:

The present invention relates to a width adjustable display stand which has the width adjustable to fit a width of a cosmetic product packaged in predetermined wrapping paper such as a mask pack, thereby being able to display a variety of items on one display stand, and has a support member disposed at the rear of items displayed on the display stand, position and inclination of which can be adjusted, such that the items are prevented from being inclined and displayed in an upright position as the items are arranged closely to each other and moved towards the front, and the support member is moved towards the front to support the rear of the items even if some items are missing from the display stand, thereby preventing degradation of the commercial value of the items. According to one embodiment of the present invention, the display stand comprises: side wall members arranged on both left and right sides to form a display space therein and having a plurality of holding grooves formed in ...

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Номер записи: 8
03-02-2016 дата публикации

BEARING PLATE STRUCTURE AND CONSTRUCTION METHOD FOR BUOYANCY ANCHOR USING SAME

Номер: KR1020160012512A
Автор: KIM, DEOK HYEONG
Принадлежит:

The present invention relates to a bearing plate structure and a construction method for a buoyancy anchor using the same. The bearing plate structure (100) of a buoyancy anchor comprises: a lower bearing plate (110) coming in contact with the ground, and having a through hole (111) to be connected to a bored hole (1); an upper bearing plate (120) formed on an upper part of the lower bearing plate (110) at intervals, and having an anchoring hole (121) in order for an anchor body (20) inserted into the bored hole (1) to be inserted and mounted; and a spacer member (130) installed between the lower bearing plate (110) and the upper bearing plate (120) to maintain a gap between the lower bearing plate (110) and the upper bearing plate (120). The bearing plate structure is able to reduce construction time and costs by preventing unnecessary construction by finishing a work of the buoyancy anchor by placing a construction company of the buoyancy anchor once. COPYRIGHT KIPO 2016 ...

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Номер записи: 9
15-10-2015 дата публикации

CONSTRUCTION METHOD FOR EXTRACTING PILE AND CONSTRUCTION SUPPORT DEVICE FOR EXTRACTING PILE

Номер: KR101556763B1
Автор: AN, JAE CHEON, KIM, DUCK HYOUNG
Принадлежит: GEOWON ENGINEERING CO., LTD., DOWON FOUNDATION&GROUTING CO., LTD.

The present invention relates to a construction method for extracting a pile and a construction support device for extracting a pile and, more specifically, to a construction method for extracting a pile and a construction support device for extracting a pile, wherein a process for extracting a pile used in case of excavation work is short and simple to improve construction ability, reduce a construction cost, and further, shorten a construction period. According to the present invention, the construction support device for extracting a pile comprises: a coating layer formed in the whole or at least one side of a circumference of the pile; a guide rail formed along a longitudinal direction in an inner side of a recessed groove portion which is formed in the pile; and an earth pressure support plate inserted into and installed in the guide rail. COPYRIGHT KIPO 2016 ...

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Номер записи: 10
11-10-2018 дата публикации

METHOD FOR PREPARING POSITIVE ELECTRODE ACTIVE MATERIAL, POSITIVE ELECTRODE ACTIVE MATERIAL PREPARED BY METHOD AND LITHIUM SECONDARY BATTERY COMPRISING SAME

Номер: KR1020180111323A
Автор: KWAK, ICK SOON, KIM, DEOK HYEONG, KANG, SEONG HOON, KIM, DO HYUNG, SONG, CHI HYEON, KWON, BYEONG GUK, CHAE, CHANG WAN
Принадлежит:

The present invention provides a method for preparing a positive electrode active material, which comprises: a step in which a positive electrode active material precursor and a lithium raw material are added to a calcination furnace; a temperature rise step for performing calcination while raising a calcination temperature of the calcination furnace; and a holding step for holding the heated calcination temperature and performing calcination when the temperature rise is completed, wherein the heating step includes a step for performing calcination in a gas atmosphere containing at least 20 vol% of pure oxygen and the remainder being air, and the holding step includes a step for performing calcination in an air atmosphere. The residual amount of the lithium-containing impurity is reduced to realize high capacity with excellent charge/discharge capacity characteristics, and at the same time, it is possible to secure excellent life characteristics, chemical and thermal stability. COPYRIGHT ...

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Номер записи: 11
02-11-2017 дата публикации

CHLAMYDOMONAS MUTANTS DEVELOPED USING RGEN RNP AND METHOD FOR PRODUCING PIGMENT USING SAME

Номер: KR1020170121688A
Автор: BAE, SANG SU, JIN, EON SEON, BAEK, KWANG RYUL, KIM, DUK HYOUNG, JEONG, JOO YEON
Принадлежит:

The present invention relates to a new algae having pigment-enhanced pigment production ability, in which when mutants of the present invention is used, it is possible to produce a carotenoid-based pigment, specifically, xanthophyll by consuming less energy, so that the pigment can be efficiently produced at an industrial level. In addition, the mutants can be applied as a raw material for food containing a pigment, health functional food, and medicines. In particular, a process of preparing the mutants is not expected to be regulated as GMO since a DNA fragment is not likely to be inserted into a target base sequence or a target foreign base sequence, and thus it is expected that the mutants can have a great economic effect in industrial aspect of producing lutein and zeaxanthin using microalgae. COPYRIGHT KIPO 2017 ...

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Номер записи: 12
22-02-2016 дата публикации

CONSTRUCTION METHOD FOR BUOYANCY PROTECTION ANCHOR

Номер: KR0101596245B1
Автор: 김덕형
Принадлежит: 도원에프앤지(주)

... 본 발명은 지면에 면접촉하도록 형성됨과 아울러, 천공 홀(1)과 연통하도록 관통공(111)이 형성된 하부 지압판(110); 하부 지압판(110)의 상부에 이격하여 형성됨과 아울러, 천공 홀(1)에 삽입된 앵커체(20)가 삽입 및 정착되도록 정착공(121)이 형성된 상부 지압판(120); 하부 지압판(110) 및 상부 지압판(120)의 간격을 유지하도록, 하부 지압판(110) 및 상부 지압판(120)의 사이에 설치된 간격부재(130);를 포함하는 부력앵커의 지압판 구조물(100)을 제시함으로써, 부력앵커의 시공업체의 1회 투입에 의해 부력앵커 작업이 종료되도록 함으로써, 번거로운 시공을 방지하여 공사기간 및 비용을 줄일 수 있도록 한다.

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Номер записи: 13
04-10-2016 дата публикации

혈액 응고인자 Ⅷ 유전자를 타겟으로 하는 엔도뉴클레아제 및 이의 용도

Номер: KR0101658135B1
Автор: 김동욱, 김진수, 박철용, 김덕형
Принадлежит: 연세대학교 산학협력단, 기초과학연구원

... 본 발명은 정상 혈액 응고인자 Ⅷ(F8) 유전자의 역위 유발 방법, 역위가 발생한 혈액 응고인자 Ⅷ(F8) 유전자의 역위 교정 방법 및 이를 이용하여 제작된 역위가 교정된 A형 혈우병 환자-유래 유도만능 줄기세포에 관한 것이다. 본 발명의 방법은 중증 A형 혈우병의 원인 중 다수를 차지하는 F8 유전자의 인트론 1 및 인트론 22의 역위를 효율적으로 재현함으로써, A형 혈우병의 발병기작 연구 및 치료제 스크리닝을 위한 리서치 툴(research tool)로서 유용하게 이용될 수 있다. 또한, 본 발명의 방법으로 제작된 역위-교정 유도만능 줄기세포는 정상 유전자 또는 단백질 전달을 통한 제한적인 방법에 의하지 않고 돌연변이가 발생한 유전자형을 야생형과 같은 상태로 복구시킴으로서, A형 혈우병에 대한 효율적이고 근원적인 치료가 가능하게 한다.

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Номер записи: 14
14-08-2017 дата публикации

METHOD FOR DISPLAYING OFFLINE, TARGETED, INDIVIDUALLY SCHEDULED ADVERTISEMENTS IN DESKTOP DISPLAY

Номер: KR1020170092857A
Автор: KIM, DUK HYUNG
Принадлежит:

The present invention relates to a method for displaying offline, targeted, individually scheduled advertisements in a desktop display through software installed in a computer of a user. An active ad window can disappear in a user desktop. A window advertisement which is movable and has a dynamically changeable size is displayed. The active ad window is completely independent and isolated software. So, there is no interference with any function of other software or there is no tampering or corruption of actual core data actually used by the user. There is no access to any data of the personal computer of the user at all. It does not need for the personal computer of the user to be always connected to the Internet. It is possible to provide advertisers with reliability and computer-based media. COPYRIGHT KIPO 2017 (701) Computer screen (702) Movable display area which can change a size of an active ad window (703) Feedback display (AA) Movable window (BB) Movable ad setting window (CC) Advertisement ...

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Номер записи: 15
14-07-2016 дата публикации

ENDONUCLEASE TARGETING BLOOD COAGULATION FACTOR VIII GENE AND COMPOSITION FOR TREATING HEMOPHILIA COMPRISING SAME

Номер: WO2016111546A9
Автор: KIM, Dong Wook, KIM, Jin Soo, PARK, Chul Yong, KIM, Duk Hyoung, KIM, Jung Eun, KWEON, Ji Yeon
Принадлежит:

The present invention provides a method for inducing an inversion of normal blood coagulation factor VIII (F8) gene, a method for correcting an inversion of blood coagulation factor VIII gene in which the inversion has occurred, and a Hemophilia A patient-derived induced pluripotent stem cell in which the inversion is corrected, constructed using the same. The method of the present invention effectively reproduces the inversion of intron 1 and intron 22 of the F8 gene, which is responsible for the majority of severe hemophilia A, and thereby may be effectively used for studying the development mechanism of hemophilia A and as a research tool for screening therapeutic agents. The inversion-corrected induced pluripotent stem cell constructed according the method of the present invention enables an efficient and fundamental treatment for hemophilia A by restoring a genotype in which mutation has occurred to a wild type-like state, without limitation via normal gene or protein delivery.

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Номер записи: 16
14-08-2017 дата публикации

ADVERTISEMENT BOARD FIXING STRUCTURE OF PRODUCT DISPLAY APPARATUS

Номер: KR1020170092860A
Автор: KIM, DUK HYUNG
Принадлежит:

The present invention relates to an advertisement board fixing structure of a product display apparatus. More specifically, the advertisement board fixing structure is used to advertise products on upper and side surfaces of the product display apparatus displaying products such as cigarettes or cosmetic products by easily fixing and replacing an advertisement board with bolts or adhesive agents. According to the present invention, the advertisement board fixing structure includes: a product display drawer which has fixing tools formed on the upper part of product display shelves and fixing holes formed on the exterior of the side surfaces of the product display shelves to be formed by laminating the product display shelves together; a clamp unit which has elastic protrusions formed on the lower part with engaging steps while having clamp plates formed on the upper part to be inserted into the fixing tools formed on the upper surface of the product display drawer; an upper advertisement ...

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Номер записи: 17