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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 36. Отображено 36.
07-02-2013 дата публикации

APPARATUS FOR MEASURING AND TREATING DYSPHAGIA

Номер: WO2013019069A2
Автор: YOU, Heecheon, LEE, Baekhee, JUNG, Kihyo, YANG, Giltae, HONG, Saewon, NA, Duk Lyul, LEE, Youngho
Принадлежит:

According to one embodiment of the present invention, an apparatus for measuring and treating dysphagia may comprise: one or more dysphagia measuring sensor units attached to the neck of a patient; one or more electrical stimulation electrode units attached to the neck of the patient to provide electrical stimulation to the neck of the patient in accordance with the dysphagia signal sensed by the dysphagia measuring sensor units so as to resolve the dysphagia; and a control unit which controls the dysphagia measuring sensor units and the electrical stimulation electrode units. Accordingly, the apparatus for measuring and treating dysphagia according to the one embodiment of the present invention has the dysphagia measuring sensor units, and the electrical stimulation electrode units which provide electrical stimulation to the neck of the patient in accordance with the dysphagia signal sensed by the dysphagia measuring sensor units so as to resolve the dysphagia, thus simultaneously enabling ...

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Номер записи: 1
09-05-2019 дата публикации

APPARATUS AND METHOD FOR INTRA-CEREBRAL DRUG INJECTION

Номер: WO2019088690A1
Автор: NA, Duk Lyul, LEE, Jeongmin, JUNG, Wooram, LEE, Jung-Il
Принадлежит:

Provided is an apparatus for intra-cerebral drug injection, the apparatus comprising: a body part having a through-hole extending between a first opening on the top-most surface and a second opening on the bottom-most surface; a cap part which has a shape corresponding to at least a part of the inner surface of the through-hole, and which is inserted into the first opening to cover same; and a tube part, one end of which is attached to the second opening and the other end of which extends toward the affected intra-cerebral area.

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Номер записи: 2
24-08-2017 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF MUSCLE DISEASE, COMPRISING MESENCHYMAL STEM CELL OR XCL1

Номер: WO2017142367A1
Автор: CHANG, Jong Wook, NA, Duk Lyul, LEE, Ji Eun, KWON, Soo Jin
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating a muscle disease, the composition comprising mesenchymal stem cells, or an XCL1 protein or a derivative thereof, and a method for screening a muscle disease-treating agent. Effective in inhibiting the death of muscle cells or myoblasts, the mesenchymal stem cells or the XCL1 protein of the present invention can be usefully used for preventing or treating muscle diseases, and an inhibitory agent against cell death, containing an XCL1 protein can be used for cell death studies.

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Номер записи: 3
28-03-2019 дата публикации

STEM CELL DOSAGE FORMULATION CONTAINING CEREBROSPINAL FLUID AND METHOD FOR PRODUCING SAME

Номер: WO2019059741A1
Автор: NA, Duk Lyul, CHANG, Jong Wook, LEE, Jeong Min
Принадлежит:

The present invention relates to a stem cell dosage formulation and a method for producing the same. The stem cell dosage formulation and the method for producing the same according to one aspect of the present invention are safe in terms of the immune system and also have the effect in which gene or protein expression of a stem cell is changed in a patient-customized manner while retaining stem cell properties, or gene or protein expression is further activated.

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Номер записи: 4
21-03-2018 дата публикации

THERAPEUTIC AGENT FOR DEGENERATIVE BRAIN DISEASES THROUGH ACTIVITY ENHANCEMENT OF UBIQUITIN PROTEASOME INCLUDING MESENCHYMAL STEM CELLS OR AgRP

Номер: KR1020180029841A
Автор: CHANG, JONG WOOK, NA, DUK L., LEE, NA KYUNG
Принадлежит:

A composition comprising mesenchymal stem cells, AgRP, or an active fragment thereof according to one aspect of the present invention can be usefully used for preventing, treating, or ameliorating a disease associated with decreased ubiquitin proteasome activity, for example, degenerative brain diseases by increasing the activity of ubiquitin proteasome. COPYRIGHT KIPO 2018 ...

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Номер записи: 5
03-05-2018 дата публикации

METHOD FOR MEASURING CHANGE OF CELL IN REAL TIME AND DEVICE THEREFOR

Номер: WO2018079891A1
Автор: HEO, Manseung, CHANG, Eunhyuk, NA, Duk L, LEE, Kyusung
Принадлежит:

Provided are a method and a device capable of: generating a first alternating current magnetic field passing through a chamber having a cell disposed therein, by using a plurality of primary coils arranged on a first plane; receiving a second alternating current magnetic field by using a plurality of secondary coils arranged on a second plane; and measuring an impedance change of a cell by using the first alternating current magnetic field and the second alternating current magnetic field.

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Номер записи: 6
03-05-2012 дата публикации

BRAIN-TRAINING SYSTEM USING AN EXERCISE BICYCLE

Номер: WO2012057544A2
Автор: YOU, Heecheon, NA, Duk Lyul, YANG, Giltae, CHOI, Young-Geun
Принадлежит:

According to one embodiment of the present invention, a brain-training system using an exercise bicycle comprises: a display device which reproduces the video selected by a user on a screen; a control box for controlling the display device; and a driving device which is driven by the physical driving force of the user so as to generate a driving information signal, and which transmits the driving information signal to the control box, wherein the control box controls the video reproduction operation of the display device in accordance with the driving information signal transmitted from the driving device.

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Номер записи: 7
03-05-2012 дата публикации

MUSICAL SYSTEM FOR PROMOTING BRAIN HEALTH

Номер: WO2012057522A3
Автор: YOU, Heecheon, KIM, Yeona, KIM, Dongmin, JEON, Yeonghwan, KIM, Donghwan, HONG, Won Gi, YANG, Giltae, NA, Duk Lyul
Принадлежит:

According to one embodiment of the present invention, a musical system for promoting brain health comprises: a display device for displaying a visual signal in accordance with selected music; a control box for controlling the display device in accordance with a user input; and a controller which has an acceleration sensor, and which drives the acceleration sensor in accordance with the motion of a user to transmit a signal to the control box. The control box processes the signal transmitted from the controller by comparing the signal and a signal for controlling the display device, and outputs the result of the process.

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Номер записи: 8
30-01-2019 дата публикации

기계 학습을 기반으로 한 알츠하이머 병 결정 방법 및 장치

Номер: KR0101944069B1
Автор: 서상원, 나덕렬, 김창수, 성준경, 김낙영
Принадлежит: 주식회사 마이다스아이티, 연세대학교 산학협력단, 고려대학교 산학협력단, 사회복지법인 삼성생명공익재단

... 기계 학습을 기반으로 한 알츠하이머 병 결정 방법은, 알츠하이머 병 결정 장치가 정상인 그룹의 뇌 영상으로부터 추출된 제1 대뇌 피질 형상 및 알츠하이머 병 환자 그룹의 뇌 영상으로부터 추출된 제2 대뇌 피질 형상에 대한 영상 처리를 수행하여 정점 샘플링된 제1 대뇌 피질 형상 및 정점 샘플링된 제2 대뇌 피질 형상을 생성하는 단계; 알츠하이머 병 결정 장치가 정점 샘플링된 제1 대뇌 피질 형상 및 정점 샘플링된 제2 대뇌 피질 형상에 대한 노이즈 제거 절차를 진행하여 정점 샘플링된 제1 대뇌 피질 형상에서 제1 특징 벡터를 추출하고, 정점 샘플링된 제2 대뇌 피질 형상에서 제2 특징 벡터를 추출하는 단계; 알츠하이머 병 결정 장치가 제1 특징 벡터 및 제2 특징 벡터를 기반으로 알츠하이머 병의 결정을 위한 판단 기준을 결정하는 단계; 및 알츠하이머 병 결정 장치가 새롭게 입력된 입력 대뇌 피질 형상에 대하여 판단 기준을 기반으로 알츠하이머 병의 발병 여부를 결정하는 단계를 포함할 수 있다.

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Номер записи: 9
03-05-2012 дата публикации

MUSICAL SYSTEM FOR PROMOTING BRAIN HEALTH

Номер: WO2012057522A2
Автор: YOU, Heecheon, KIM, Yeona, KIM, Dongmin, JEON, Yeonghwan, KIM, Donghwan, HONG, Won Gi, YANG, Giltae, NA, Duk Lyul
Принадлежит:

According to one embodiment of the present invention, a musical system for promoting brain health comprises: a display device for displaying a visual signal in accordance with selected music; a control box for controlling the display device in accordance with a user input; and a controller which has an acceleration sensor, and which drives the acceleration sensor in accordance with the motion of a user to transmit a signal to the control box. The control box processes the signal transmitted from the controller by comparing the signal and a signal for controlling the display device, and outputs the result of the process.

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Номер записи: 10
27-11-2014 дата публикации

APPARATUS FOR INTRACEREBRAL INJECTION OF DRUGS, ASSEMBLY FOR PROVIDING APPARATUS FOR INTRACEREBRAL INJECTION OF DRUGS, AND METHOD FOR INTRACEREBRAL ADMINISTRATION OF BRAIN DISEASE TREATMENT DRUGS

Номер: WO2014189253A2
Автор: NA, Duk L
Принадлежит:

An apparatus for intracerebral injection of drugs according to the present invention, comprises: a chamber (130) having one open side, inner space (135) in a concave shape, and a projection section (138) on the bottom surface (131a) thereof; a catheter (140), which is a thin and long pipe-shape member, and having a distal end (142) inserted into the projection section (138) of the chamber; a catheter fixing cap (150) for fixing the distal end (142) to the projection section (138) of the chamber (130) by being coupled with the projection section (138) of the chamber (130); a blocking disc (170) for blocking the open side of the chamber (130) by being inserted into the inner space (135) of the chamber (130); and an upper part cap (160) inserted into the inner space (135) of the chamber (130) and located in the upper part of the blocking disc (170), and the apparatus can be used in the administration of a stem cell or a brain disease treatment drug for all cerebral regions.

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Номер записи: 11
03-05-2018 дата публикации

METHOD FOR ENHANCING PROLIFERATION CAPABILITY OF STEM CELLS USING ETHIONAMIDE

Номер: WO2018080038A1
Автор: NA, Duk Lyul, CHANG, Jong Wook, SON, Hyo Jin, MYEONG, Su Hyeon
Принадлежит:

The present invention relates to a medium composition for enhancing proliferation of stem cells, comprising ethionamide, and a use thereof. It is possible, according to the present invention, to mass-produce highly-efficient next-generation stem cells through a simple and safe method of controlling a culturing environment, without using genetic modification or viral vectors, etc.

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Номер записи: 12
05-10-2018 дата публикации

APPARATUS AND METHOD FOR DIAGNOSING NERVOUS DISORDER USING VIRTUAL REALITY

Номер: KR1020180108954A
Автор: NA, DUK LYUL, KIM, KO WOON, CHIN, JU HEE, LEE, BYUNG HWA, CHOI, JONG DOO, CHOI, JEE HYUN, HAN, HIO BEEN
Принадлежит:

The present invention relates to an apparatus and method for diagnosing neurological dementia using virtual reality. The method includes the steps of: receiving a problem for a nervous disorder received from an external device; enabling a display to display a virtual reality environment based on the problem for a nervous disorder; and sensing a motion of a user through a sensing unit. The step of displaying the virtual reality environment includes the steps of: displaying a first screen to introduce at least one item and then hide the item in a virtual reality space; and displaying a second screen including a question about the at least one item. Accordingly, the present invention can easily diagnose the nervous disorder and reduce the mental stress of a patient. COPYRIGHT KIPO 2018 (101) PC (computer) (104) Smartphone (106) Server (110) Bus (120) Processor (130) Memory (141) Kernel (143) Middleware (145) Application programming interface (API) (147) Application (150) Input/output interface ...

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Номер записи: 13
21-06-2018 дата публикации

COMPOSITION COMPRISING MESENCHYMAL STEM CELLS OR ACTIVIN A FOR TREATING DEGENERATIVE BRAIN DISEASES

Номер: KR1020180068119A
Автор: CHANG, JONG WOOK, NA, DUK L, PARK, SANG EON
Принадлежит:

The present invention provides a pharmaceutical composition for treating degenerative brain diseases. The pharmaceutical composition comprising mesenchymal stem cells, a lysate thereof, an extract thereof, or Activin A may be used to increase differentiation of neural stem cells in the brain, for example, in the ventral estuary, and to be useful for treating degenerative brain diseases. COPYRIGHT KIPO 2018 ...

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Номер записи: 14
03-05-2018 дата публикации

METHOD FOR IMPROVING STEM CELL PROLIFERATION ABILITY USING CHENODEOXYCHOLIC ACID

Номер: KR1020180044760A
Автор: NA, DUK LYUL, CHANG, JONG WOOK, SON, HYO JIN, MYEONG, SU HYEON
Принадлежит:

The present invention relates to a culture medium composition for improving stem cell proliferation ability containing chenodeoxycholic acid, and a use thereof. According to the present invention, it is possible to mass-produce next generation of highly efficient stem cells via a simple and safe method of regulating culture environment without genetic manipulation, uses of viral vectors or the like. COPYRIGHT KIPO 2018 ...

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Номер записи: 15
29-03-2018 дата публикации

METHOD FOR SCREENING PATIENT-SPECIFIC STEM CELL THERAPEUTIC AGENT

Номер: WO2018056616A1
Автор: CHANG, Jong Wook, NA, Duk Lyul, LEE, Jeong Min
Принадлежит:

The present invention relates to a method for screening a patient-specific therapeutic agent. When using the method for screening a patient-specific therapeutic agent of the present invention, it is possible to identify and select the therapeutic ability of mesenchymal stem cells of different origins with respect to disease subtypes or disease effectors. In addition, it is possible to confirm the characteristics of the secretory protein which acts at high efficiency or low efficiency, by analyzing proteins secreted by the selected mesenchymal stem cells, and thus there is the advantage that a customized therapeutic agent for the specific nature of the disease of each patient can be proposed.

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Номер записи: 16
11-12-2015 дата публикации

BIOLOGICAL BRAIN AGE CALCULATION APPARATUS AND CALCULATION METHOD THEREOF

Номер: KR1020150139307A
Автор: NA, DUK L., SEO, SANG WON, SEONG, JUN KYUNG, KIM, CHANG SOO
Принадлежит:

The present invention relates to a biological brain age calculation apparatus which measures the thickness of a regional brain cortex in the brain MRI image of a testee and calculates the biological brain age by comparing the same with the normal control group, and a calculation method thereof. The biological brain age calculation apparatus includes: an image information input part which inputs the MRI brain image of a testee, a brain age calculation control part which controls the biological brain age calculation process of the testee based on the MRI brain image, a brain thickness measuring part which measures the thickness of a regional brain cortex in the brain MRI image, and a brain age calculation part which calculates the biological brain age of the testee by matching a measured brain cortex thickness to a brain thickness normal range according to age. COPYRIGHT KIPO 2016 (10) Image information input part (20) Brain age calculation control part (30) Examination object information ...

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Номер записи: 17
02-04-2018 дата публикации

METHOD FOR SCREENING PATIENT-SPECIFIC STEM CELL THERAPEUTIC AGENT

Номер: KR1020180033062A
Автор: CHANG, JONG WOOK, NA, DUK LYUL, LEE, JEONG MIN
Принадлежит:

The present invention relates to a method for screening a patient-specific therapeutic agent. When using the method for screening a patient-specific therapeutic agent of the present invention, it is possible to identify and select the therapeutic ability of mesenchymal stem cells of different origins with respect to disease subtypes or disease effectors. In addition, it is possible to confirm the characteristics of a secretory protein which acts at high efficiency or low efficiency, by analyzing proteins secreted by the selected mesenchymal stem cells, and thus there is the advantage that a customized therapeutic agent for the specific nature of the disease of each patient can be proposed. COPYRIGHT KIPO 2018 ...

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Номер записи: 18
22-04-2016 дата публикации

Intracerebral drug injection device, the assembly for installing the injection device

Номер: KR0101614881B1
Автор: 나덕렬
Принадлежит: 사회복지법인 삼성생명공익재단

... 본 발명에 따른 뇌내 약물 주입장치는, 일면이 개방되고, 오목한 형태의 내부 공간(135)을 가지며, 밑면(131a)에는 돌출부(138)가 형성된 챔버(130); 가늘고 긴 관형의 부재로서, 그 원위단부(142)가 상기 챔버(130)의 돌출부(138)에 끼워지는 카테타(140); 상기 챔버(130)의 돌출부(138)에 결합됨으로써, 상기 카테타(140)의 원위단부((142)를 상기 챔버(130)의 돌출부(138)에 고정시키는 카테타 고정캡(150); 상기 챔버(130)의 내부공간(135)에 삽입되어 상기 챔버(130)의 개방된 면을 막는 막음 디스크(170); 및 상기 챔버(130)의 내부공간(135)에 끼워지되, 상기 막음 디스크(170)의 상부에 위치하는 상부캡(160);을 포함하며, 모든 뇌실질 부위를 대상으로 줄기세포 또는 뇌질환 치료약물을 투여하는데 사용될 수 있다.

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Номер записи: 19
29-08-2017 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF MUSCLE DISEASE, COMPRISING MESENCHYMAL STEM CELL OR XCL1

Номер: KR1020170098046A
Автор: CHANG, JONG WOOK, NA, DUK LYUL, LEE, JI EUN, KWON, SOO JIN
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating a muscle disease, which comprises mesenchymal stem cells, or an XCL1 protein or a derivative thereof, and also relates to a method for screening a muscle disease-treating agent. Since there is an effect in inhibiting the death of muscle cells or myoblasts, the mesenchymal stem cells or the XCL1 protein of the present invention can be usefully used for preventing or treating muscle diseases, and an inhibitory agent against cell death, containing an XCL1 protein can be used for cell death studies. COPYRIGHT KIPO 2017 ...

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Номер записи: 20
07-02-2013 дата публикации

APPARATUS FOR MEASURING AND TREATING DYSPHAGIA

Номер: WO2013019069A3
Автор: YOU, Heecheon, LEE, Baekhee, JUNG, Kihyo, YANG, Giltae, HONG, Saewon, NA, Duk Lyul, LEE, Youngho
Принадлежит:

According to one embodiment of the present invention, an apparatus for measuring and treating dysphagia may comprise: one or more dysphagia measuring sensor units attached to the neck of a patient; one or more electrical stimulation electrode units attached to the neck of the patient to provide electrical stimulation to the neck of the patient in accordance with the dysphagia signal sensed by the dysphagia measuring sensor units so as to resolve the dysphagia; and a control unit which controls the dysphagia measuring sensor units and the electrical stimulation electrode units. Accordingly, the apparatus for measuring and treating dysphagia according to the one embodiment of the present invention has the dysphagia measuring sensor units, and the electrical stimulation electrode units which provide electrical stimulation to the neck of the patient in accordance with the dysphagia signal sensed by the dysphagia measuring sensor units so as to resolve the dysphagia, thus simultaneously enabling ...

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Номер записи: 21
27-11-2014 дата публикации

APPARATUS FOR INTRACEREBRAL INJECTION OF DRUGS, ASSEMBLY FOR PROVIDING APPARATUS FOR INTRACEREBRAL INJECTION OF DRUGS, AND METHOD FOR INTRACEREBRAL ADMINISTRATION OF BRAIN DISEASE TREATMENT DRUGS

Номер: WO2014189253A3
Автор: NA, Duk L
Принадлежит:

An apparatus for intracerebral injection of drugs according to the present invention, comprises: a chamber (130) having one open side, inner space (135) in a concave shape, and a projection section (138) on the bottom surface (131a) thereof; a catheter (140), which is a thin and long pipe-shape member, and having a distal end (142) inserted into the projection section (138) of the chamber; a catheter fixing cap (150) for fixing the distal end (142) to the projection section (138) of the chamber (130) by being coupled with the projection section (138) of the chamber (130); a blocking disc (170) for blocking the open side of the chamber (130) by being inserted into the inner space (135) of the chamber (130); and an upper part cap (160) inserted into the inner space (135) of the chamber (130) and located in the upper part of the blocking disc (170), and the apparatus can be used in the administration of a stem cell or a brain disease treatment drug for all cerebral regions.

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Номер записи: 22
09-07-2018 дата публикации

METHOD FOR DETERMINING ALZHEIMER′S DISEASE BASED ON MACHINE LEARNING, AND APPARATUS FOR SAME

Номер: KR1020180078033A
Автор: SEO, SANG WON, NA, DUK LYUL, KIM, CHANG SOO, SEONG, JUN KYUNG, KIM, NAK YOUNG
Принадлежит:

The present invention relates to a method for determining Alzheimer′s disease based on machine learning, which comprises the steps of: generating, by an Alzheimer′s disease determining apparatus, first and second cerebral cortical shapes which are vertex-sampled by performing image processing for a first cerebral cortical shape extracted from a brain image of a non-patient group and a second cerebral cortical shape extracted from a brain image of a patient group having Alzheimer′s disease; performing, by the Alzheimer′s disease determining apparatus, a noise removal procedure for the vertex-sampled first and second cerebral cortical shapes to extract a first feature vector from the vertex-sampled first cerebral cortex shape, and to extract a second feature vector from the vertex-sampled second cerebral cortex shape; determining, by the Alzheimer′s disease determining apparatus, a determination criterion for determining the Alzheimer′s disease on the basis of the first and second feature ...

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Номер записи: 23
10-05-2018 дата публикации

APPARATUS AND METHOD FOR MEASURING CHANGES OF CELL IN REAL-TIME

Номер: KR1020180047403A
Автор: HEO, MAN SEUNG, CHANG, EUN HYUK, NA, DUK L, LEE, KYU SUNG
Принадлежит:

Provided are a method and an apparatus. The apparatus generates a first alternating current magnetic field passing through a chamber in which a cell is arranged with a plurality of first coils arranged on a first plane, receives a second alternating current magnetic field with a plurality of second coils arranged on a second plane, and measures a change in impedance of the cell with the first alternating current magnetic field and the second alternating current magnetic field. COPYRIGHT KIPO 2018 (140) Control unit (AA) Induction magnetic field generating circuit (BB) Induction magnetic field receiving circuit ...

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Номер записи: 24
22-03-2018 дата публикации

AGENT COMPRISING MESENCHYMAL STEM CELL OR AGRP FOR TREATMENT OF DEGENERATIVE BRAIN DISEASE THROUGH INCREASE IN UBIQUITIN PROTEASOME ACTIVITY

Номер: WO2018052182A1
Автор: CHANG, Jong Wook, NA, Duk L., LEE, Na Kyung
Принадлежит:

A composition comprising mesenchymal stem cells, or AgRP or an active fragment thereof according to one aspect has the effect of being useful for preventing, treating, or alleviating a disease associated with decrease activity of ubiquitin proteasome, for example, a degenerative brain disease by increasing the activity of ubiquitin proteasome.

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Номер записи: 25
03-05-2012 дата публикации

BRAIN-TRAINING SYSTEM USING AN EXERCISE BICYCLE

Номер: WO2012057544A3
Автор: YOU, Heecheon, NA, Duk Lyul, YANG, Giltae, CHOI, Young-Geun
Принадлежит:

According to one embodiment of the present invention, a brain-training system using an exercise bicycle comprises: a display device which reproduces the video selected by a user on a screen; a control box for controlling the display device; and a driving device which is driven by the physical driving force of the user so as to generate a driving information signal, and which transmits the driving information signal to the control box, wherein the control box controls the video reproduction operation of the display device in accordance with the driving information signal transmitted from the driving device.

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Номер записи: 26
03-03-2016 дата публикации

SYSTEM AND METHOD FOR MEASURING NUMBER OF SWALLOWING TIME

Номер: KR1020160023345A
Автор: LEE, BAEK HEE, LEE, SEUNG HOON, YOU, HEE CHEON, YANG, GIL TAE, CHEON, HO JUN, HONG, SAE WON, LEE, YOUNG HO, NA, DUK L.
Принадлежит:

Disclosed are a system and method for measuring the number of swallowing times. The system comprises: an iron movement sensing unit (100) having an ultrasonic wave doppler sensor attached to the outside of the neck to measure upward and downward movement of an iron; a sound sensing unit (200) disposed in parallel with the iron movement sensing unit to measure a sound; and a data analyzing unit (300) for analyzing an iron movement signal measured by the iron movement sensing unit and a sound signal measured from the sound sensing unit. COPYRIGHT KIPO 2016 (300) Data analyzing unit (310) Data integrated managing unit (320) Noise removing unit (330) Number of swallowing detecting unit ...

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Номер записи: 27
03-05-2018 дата публикации

METHOD FOR IMPROVING STEM CELL PROLIFERATION ABILITY USING ETHIONAMIDE

Номер: KR1020180044801A
Автор: NA, DUK LYUL, CHANG, JONG WOOK, SON, HYO JIN, MYEONG, SU HYEON
Принадлежит:

The present invention relates to a culture medium composition for improving stem cell proliferation ability containing ethionamide, and a use thereof. According to the present invention, it is possible to mass-produce next generation of highly efficient stem cells through regulation of culture condition in a simple and safe way, without genetic manipulation or uses of viral vectors. COPYRIGHT KIPO 2018 ...

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Номер записи: 28
09-07-2018 дата публикации

METHOD AND APPARATUS FOR SUBTYPE CLASSIFICATION OF ALZHEIMER′S DISEASE BASED ON SHRINKING OF CEREBRAL CORTEX

Номер: KR1020180078032A
Автор: SEONG, JUN KYUNG, KIM, NAK YOUNG, NA, DUK LYUL
Принадлежит:

The subtype classification method of Alzheimer′s disease based on the degree of shrinking of cerebral cortex comprises the following steps of an Alzheimer′s disease subtype classification apparatus: performing image processing on a first cerebral cortex shape extracted from brain images of a normal group and a second cerebral cortex shape extracted from brain images of an Alzheimer′s disease patient group and generating a vertex-sampled first cerebral cortex shape and a vertex-sampled second cerebral cortex shape; determining cerebral cortex shrinking patterns by calculating the degree of shrinking of the cerebral cortex of the Alzheimer′s disease patient group based on the resampled first cerebral cortex shape and the resampled second cerebral cortex shape; and grouping and classifying the resampled second cerebral cortex shape into a plurality of subtypes based on the similarity between the cerebral cortex shrinking patterns. COPYRIGHT KIPO 2018 (AA) Start (BB) End (S100) Performing pre-processing ...

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Номер записи: 29
27-09-2018 дата публикации

NEUROLOGICAL DISORDER DIAGNOSIS DEVICE AND METHOD WHICH USE VIRTUAL REALITY

Номер: WO2018174507A1
Автор: NA, Duk Lyul, KIM, Ko Woon, JIN, Ju Hee, LEE, Byung Hwa, CHOI, Jong Doo, CHOI, Jee Hyun, HAN, Hio Been
Принадлежит:

The purpose of the present invention is to diagnose a neurological disease such as dementia by using virtual reality, and the present invention receives a neurological disease-diagnosing problem from an external device, displays a virtual reality image through a display on the basis of the received neurological disease-diagnosing problem, and performs an examination using the virtual reality image according to user actions detected through various sensors. This process can be performed when linked with an external device such as a PC or a smart phone. Particularly, with respect to the neurological disease-diagnosing problem, the present invention includes: a first screen for introducing at least one object in a virtual reality space and hiding the same; and a second screen having a question on the hidden object. According to the present invention, neurological disease such as dementia can be conveniently examined without inconveniencing or burdening a patient.

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Номер записи: 30
18-05-2016 дата публикации

Biological brain age calculation apparatus and the method

Номер: KR0101620302B1
Автор: 나덕렬, 서상원, 성준경, 김창수
Принадлежит: 사회복지법인 삼성생명공익재단, 고려대학교 산학협력단, 연세대학교 산학협력단

... 본 발명은 검사 대상자의 뇌 MRI 영상에서 영역별 뇌피질 두께를 측정하고, 이를 정상 대조군 정보와 비교하여 생물학적 뇌연령을 산출하는 장치 및 방법에 관한 것으로, 검사 대상자의 MRI 뇌 영상을 입력하는 영상정보 입력부, 상기 MRI 뇌 영상을 기반으로 상기 검사 대상자의 생물학적 뇌연령 산출 작업을 제어하는 뇌연령 산출 제어부, 상기 MRI 뇌 영상에서 영역별 뇌피질 두께를 측정하는 뇌두께 측정부 및 측정된 상기 뇌피질 두께를 연령별 뇌두께 정상 범위에 매칭하여, 상기 검사 대상자의 생물학적 뇌연령을 산출하는 뇌연령 산출부를 포함하는 것을 기술적 특징으로 한다.

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Номер записи: 31
09-05-2019 дата публикации

METHOD FOR IMPROVING STEM CELL MIGRATION USING ETHIONAMIDE

Номер: WO2019088480A2
Автор: NA, Duk Lyul, CHANG, Jong Wook, SON, Hyo Jin
Принадлежит:

The present invention relates to a culture medium composition comprising ethionamide for improving stem cell migration, and to uses for same. According to the present invention, stem cell migration can be effectively improved by means of a simple and safe method of controlling the culturing environment, without using gene manipulation, virus vectors and the like, and the stem cells having improved mobility due to the method are expected to be effectively utilized as a stem cell therapeutic agent that can rapidly migrate to and function in an area of damage following a transplantation.

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Номер записи: 32
02-03-2018 дата публикации

중간엽 줄기세포 또는 XCL1을 포함하는 근육질환의 예방 또는 치료용 약학적 조성물

Номер: KR0101833971B1
Автор: 장종욱, 나덕렬, 이지은
Принадлежит: 사회복지법인 삼성생명공익재단

... 본 발명은 중간엽 줄기세포 또는, XCL1 단백질 또는 이의 유도체를 포함하는 근육질환의 예방 또는 치료용 약학적 조성물 및 근육질환 치료제의 스크리닝 방법에 관한 것이다. 본 발명의 중간엽 줄기세포 또는 XCL1 단백질은 근육세포 또는 근육아세포 사멸을 저해하는 효과가 있으므로 근육질환의 예방 또는 치료에 유용하게 이용될 수 있으며, XCL1 단백질을 포함하는 세포사멸 저해제는 세포 사멸 연구에 활용할 수 있다.

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Номер записи: 33
10-12-2015 дата публикации

BIOLOGICAL BRAIN AGE CALCULATION DEVICE AND CALCULATION METHOD THEREFOR

Номер: WO2015186963A1
Автор: NA, Duk L., SEO, Sang Won, SEONG, Jun Kyung, KIM, Changsoo
Принадлежит:

The present invention relates to a device and a method for calculating biological brain age by measuring the brain cortex thickness of each region in a brain MRI image of a person to be inspected and by comparing the brain cortex thickness with normal control group information, the device comprising: an image information input unit for inputting an MRI brain image of a person to be inspected; a brain age calculation control unit for controlling a biological brain age calculation operation of the person to be inspected on the basis of the MRI brain image; a brain thickness measurement unit for measuring the brain cortex thickness of each region in the MRI brain image; and a brain age calculation unit for matching the measured brain cortex thickness with the normal range of brain thickness according to age so as to calculate the biological brain age of the person to be inspected.

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Номер записи: 34
31-10-2018 дата публикации

MEDICAL PRECISE SYRINGE

Номер: KR1020180118394A
Автор: NA, DUK LYUL, JUNG, WOO RAM
Принадлежит:

According to one embodiment of the present invention, provided is a medical precise syringe including a syringe main body for storing an injectable solution. The medical precise syringe comprises: a connecting member having a first connecting unit, on which a replaceable and disposable needle member is mounted, and a second connecting unit connected to the syringe main body and allowing the injectable solution to pass from the syringe main body to the needle member; and a fixing member fixing the connecting member to the syringe main body by using a coupling means while allowing the first connecting unit of the connecting member to be exposed to the outside. COPYRIGHT KIPO 2018 ...

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Номер записи: 35
18-07-2019 дата публикации

METHOD FOR IMPROVING STEM CELL MIGRATION USING ETHIONAMIDE

Номер: WO2019088480A3
Автор: NA, Duk Lyul, CHANG, Jong Wook, SON, Hyo Jin
Принадлежит:

The present invention relates to a culture medium composition comprising ethionamide for improving stem cell migration, and to uses for same. According to the present invention, stem cell migration can be effectively improved by means of a simple and safe method of controlling the culturing environment, without using gene manipulation, virus vectors and the like, and the stem cells having improved mobility due to the method are expected to be effectively utilized as a stem cell therapeutic agent that can rapidly migrate to and function in an area of damage following a transplantation.

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Номер записи: 36