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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 21. Отображено 21.
28-12-2015 дата публикации

IMMUNITY ENHANCING COMPOSITION COMPRISING RECOMBINANT G. LAMBLIA BINDING IMMUNOGLOBULIN PROTEIN

Номер: KR1020150144381A
Принадлежит:

The present invention relates to an immunity enhancing composition comprising recombinant G. lamblia binding immunoglobulin protein. The recombinant G. lamblia binding immunoglobulin protein of the present invention may be used to greatly enhance immune activation through immune responses, such as production of cytokines and maturation of the dendritic cells in mouse dendritic cells, and thus, be effectively used as an agent for enhancing immunity. In addition, the present invention may be effectively used for a method for screening epitope having immunogenicity by using the recombinant G. lamblia binding immunoglobulin protein, and for a method for screening the antibody thereof. COPYRIGHT KIPO 2016 ...

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24-11-2017 дата публикации

POLYGLUCOSAMINE POLYMER AND ANTI-INFLAMMATORY BIO-ADHESIVE COMPOSITION COMPRISING SAME

Номер: KR101800746B1
Принадлежит: MEDICOGEM INC.

The present invention relates to a bio-adhesive which can be effectively used to treat wound because having anti-inflammatory efficacy, as well as having low toxicity and strong adhesive force with an adherend, and to a producing method of the same. More specifically, the present invention relates to a poly-glucosamine polymer having a repeat unit represented by chemical formula 1, a producing method of the same, and a bio-adhesive composition comprising the poly-glucosamine polymer and cyanoacrylate. In the chemical formula 1, n is an integer of 2-1000, X is CH_2-0 or (CH_2)_y), y is 0 or 1, m is 0, 1, or 2, R is H, methyl, ethyl, acetyl, propionyl, or a butyryl group. COPYRIGHT KIPO 2017 ...

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22-11-2016 дата публикации

ANIMAL FOR WOUND DISEASE MODEL, METHOD FOR MANUFACTURING SAME, AND METHOD FOR ANALYZING EFFICACY OF WOUND TREATMENT USING SAME

Номер: KR1020160133051A
Принадлежит:

The purpose of the present invention is to overcome the limitations occurring in a case in which a mouse having a skin recovery process different from that of a human skin cell is used as a model as a wound therapeutic research, and to provide a method of manufacturing an animal for a wound disease model to be applied to a wound therapeutic research in a realistic and economical method and a method for analyzing a wound treatment efficacy using the same. Therefore, the present invention provides a wound treatment model in which a cylinder is inserted to be perpendicular to a surface of a wound to suppress a rodent epithelium-specific horizontal building capability, and including permeable hydrogel with a natural material for forming a thin film in a surface of a wound by being inserted inside. The present invention has effects of manufacturing an animal for animal model in which immune is not suppressed since not causing immune response, and using an animal for a model having conditions ...

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18-05-2015 дата публикации

PORTABLE FOCUS DETECTION APPARATUS AND METHOD FOR FOCUS DETECTION

Номер: KR1020150053296A
Принадлежит:

A portable focus detection apparatus according to an embodiment of the present invention comprises: a pan/tilt/zoom camera part photographing an observing area without blind regions and outputting the result as image signals; and a portable monitor unit detecting an edge of the image signals by being provided with the image signals from the pan/tilt/zoom camera, and outputting OSD signals by selecting and controlling the focus direction of the image signals. The portable monitor unit comprises: a signal converting unit converting the image signals into digital image signals; an edge detecting unit detecting an edge while reducing noise included in the digital image signals by being provided with the digital image signals from the signal converting unit; and outputting the OSD signals by selecting and controlling the focus direction of the digital image signals through the edge detected by the edge detecting unit. COPYRIGHT KIPO 2015 (111) Image input unit (113) OSD unit (115) Image output ...

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26-12-2018 дата публикации

SERVICE SYSTEM FOR PROVIDING ELECTRONIC MATERNITY NOTEBOOK

Номер: KR1020180136916A
Принадлежит:

The present invention relates to a service system for providing an electronic maternity notebook, which converts a maternity medical record, fetus body information, etc. into an imaged code such as a barcode or a QR code to provide the same for a user terminal such that personal medical information can be provided without being exposed to the outside. According to the present invention, fetus body information and medical information, etc. are generated as an imaged code, and medical record information is provided for a user as an imaged code, thereby providing medical information without exposure of personal information. In addition, the fetus body information is designated as a coordinate value to be generated as a code and the coordinate value is provided for the user wherein the user can visually confirm information on the coordinate value, thereby simplifying the input of the fetus body information and reducing the transmission capacity of data. COPYRIGHT KIPO 2019 (100) Administrator ...

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07-11-2018 дата публикации

SCORCHED RICE SNACK AND PREPARING METHOD THEREOF

Номер: KR1020180120941A
Автор: PARK, SOON CHUNG
Принадлежит:

The present invention relates to a method for preparing scorched rice snack, comprising the steps of: a) preparing snack ingredients by mixing scorched rice, grain syrup, salt, sub ingredients, and honey frozen food; and b) evenly spreading the snack ingredients over an iron plate and drying the same. The scorched rice snack prepared according to the present invention is free of harmful additives and has a not hard, soft, and crispy texture so that the elderly or infants feel no burden to eat, and has excellent taste and flavor to be easily eaten anywhere. In addition, according to the present invention, a nutritious snack for children of developmental age can be provided by using only healthy ingredients without adding additives which may be harmful to human body during preparing the scorched rice snack. COPYRIGHT KIPO 2018 ...

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30-01-2018 дата публикации

ADDITIVE COMPOSITION FOR BIOADHESIVES CONTAINING POLYGALLIC ACID POLYMER

Номер: KR101823054B1
Принадлежит: MEDICOGEM INC.

The present invention relates to bioadhesives which can be effectively used for treatment of wounds with its less toxicity content, easily controlled binding force and flexibility with respect to adherence, and less likelihood of infection by an effect of inhibiting the growth of microorganisms or viruses; and a method for preparing the same. More specifically, the present invention relates to a polygallic acid polymer having a gallamide branch as a repeating unit and represented by chemical formula 1; a method for preparing the same; and a bioadhesive composition containing the polygallic acid polymer and cyanoacrylate. In chemical formula 1, n is an integer ranging from 2 to 1,000, and m is an integer ranging from 1 to 7. COPYRIGHT KIPO 2018 ...

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18-01-2018 дата публикации

GALLIC ACID-CHITOSAN COMPLEX AND COMPOSITION FOR HEALING WOUND USING SAME

Номер: KR101820306B1
Принадлежит: MEDICOGEM INC.

The present invention relates to a chitosan complex which has excellent adhesion and hemostasis effects, has antibacterial efficacy and is effective in healing wounds due to high biocompatibility, and to a composition for healing wounds comprising the same and, more specifically, to a gallic acid-chitosan complex in which gallic acid is bound to chitosan by an ester bond or an ester bond and an amine bond, and a composition for healing wounds comprising the same. COPYRIGHT KIPO 2018 ...

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08-11-2018 дата публикации

METHOD OF PRODUCING BEATING CARDIOMYOCYTES FROM HUMAN EMBRYONIC STEM CELLS USING CD71 CELL SURFACE MARKER

Номер: KR101916902B1

The present invention relates to a method of inducing the differentiation from totipotent stem cells into cardiomyocytes and separating only beating cardiomyocytes using a CD71 cell surface marker. Specifically, the method provided in the present invention separates the beating cardiomyocytes in a single cell unit by a physical separation method rather than an enzyme treatment method. According to the present invention, the beating cardiomyocytes can be separated by differentiating cardiomyocytes from totipotent stem cells and selecting only CD71 positive cells, and the method can be used for cytotoxic drug-evaluating cells or therapeutic agents for heart failure cells. COPYRIGHT KIPO 2018 (AA) SIRPA(non-patent literature 2) ...

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14-09-2017 дата публикации

BIOADHESIVE COMPOSITION WITH ANTI-INFLAMMATION ACTIVITY AND PREPARATION METHOD THEREOF

Номер: KR101778651B1
Принадлежит: MEDICOGEM INC.

The present invention relates to a compound represented by chemical formula 1, a preparation method thereof and a bioadhesive composition comprising the compound as an active ingredient. In the chemical formula 1, X is CH_2-O or (CH_2)_m, wherein m is 0 or 1, n is 0, 1 or 2, and H is a methyl, ethyl, acetyl, propionyl or butyryl group. The compound has low toxicity, strong binding force and anti-inflammatory efficacy, thereby being effectively used for treating wounds. COPYRIGHT KIPO 2017 ...

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16-03-2023 дата публикации

실리카 판을 이용한 전기영동 및 그 실리카 판

Номер: KR20230037305A
Принадлежит:

... 본 발명은 실리카 판을 매트릭스로 하는 것을 특징으로 하는 전기영동 방법 및 상기 전기영동 방법에 활용되는 실리카 판에 관한 것이다.

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09-09-2015 дата публикации

PORTABLE FOCUS DETECTION APPARATUS AND METHOD

Номер: KR0101551181B1
Принадлежит: 티.비.티. 주식회사

... 본 발명의 일실시 예에 따른 휴대용 포커스 검출 장치는 사각지대없이 감시지역을 촬영하여 영상신호로 출력하는 팬/틸트/줌 카메라부와 팬/틸트/줌 카메라부로부터 영상신호를 제공받아 영상신호의 엣지를 검출하여 영상신호의 포커스의 방향을 선택하면서 제어하여 OSD신호를 출력하는 휴대용 모니터부를 포함하고, 휴대용 모니터부는 영상신호를 디지털영상신호로 변환하는 신호변환부, 신호변환부로부터 디지털영상신호로 제공받아 디지털영상신호에 포함된 노이즈를 제거하면서 엣지를 검출하는 엣지검출부 및 엣지검출부에서 검출된 엣지를 통해 디지털영상신호의 포커스의 방향을 선택하면서 제어하여 OSD신호를 출력하는 엣지제어부를 포함하며, 상기 엣지검출부는 상기 디지털영상신호에 포함된 노이즈를 제거하고 상기 엣지를 검출하면서 상기 디지털영상신호의 LPF 콘트라스트를 추출하여 상기 LPF 콘트라스트의 평균값과 최대값을 출력하는 LPF부;와 상기 엣지를 검출하면서 상기 디지털영상신호의 HPF 콘트라스트를 추출하여 상기 HPF 콘트라스트의 평균값과 최대값을 출력하는 HPF부;를 포함한다.

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13-02-2018 дата публикации

BIOADHESIVE USING GALLIC ACID AND CYANOACRYLATE, AND PRODUCTION METHOD THEREOF

Номер: KR101828434B1
Принадлежит: MEDICOGEM INC.

The present invention relates to a compound which is represented by chemical formula 1 and ensures strong adhesiveness with adhering objects, low toxicity, and low risks of infection by inhibiting growth of microbes or virus, thereby effectively used for healing wounds. The present invention further relates to a production method thereof, and a bioadhesive composition containing the same as an active ingredient. In the chemical formula 1, n is an integer of 1 to 7. COPYRIGHT KIPO 2018 ...

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28-11-2018 дата публикации

ANTISEPTIC COMPOSITION

Номер: KR101922986B1
Принадлежит: MEDICOGEM INC.

The present invention relates to an antiseptic composition which exhibits excellent antiseptic performance even when used in a small amount due to increased antiseptic performance and can be safely used as an additive for pharmaceuticals or foods and cosmetics. More particularly, the present invention relates to an antiseptic composition comprising a mixture of C5-C8 1,2-alkanediol and butylhydroxyanisole (BHA) or t-butylhydroquinone (TBHQ) as an active ingredient. COPYRIGHT KIPO 2019 (AA) 1,2-alkanediol + BHA (10:1 w / w) ...

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20-06-2016 дата публикации

Immunostimulatory Compositions Comprising Recombinant Giardia lamblia binding immunoglobulin protein

Номер: KR0101631312B1
Автор: 박순정, 이혜연, 김주리
Принадлежит: 연세대학교 산학협력단

... 본 발명은 재조합 람블편모충 결합 면역글로블린 단백질을 포함하는 면역증강 조성물에 관한 것이다. 본 발명은 동정된 재조합 람블편모충 결합 면역글로블린 단백질(recombinant G. lamblia binding immunoglobulin protein, rGlBiP)이 마우스 수지상 세포에서 사이토카인 생산 및 수지상 세포의 성숙과 같은 면역반응을 통해 면역 활성화를 크게 향상시킴으로써 면역증진용 제제로서 유용하게 이용될 수 있으며, 본 발명은 재조합 람블편모충 결합 면역글로블린 단백질을 이용하여 면역원성을 갖는 에피토프의 스크리닝 방법 및 이의 항체 스크리닝 방법에 유용하게 이용될 수 있다.

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02-06-2017 дата публикации

METHOD FOR CULTURING CARDIOMYOCYTES TO MAINTAIN OR ENHANCE FUNCTION THEREOF

Номер: KR1020170060620A
Принадлежит:

The present invention relates to a method for culturing cardiomyocytes to maintain or enhance a function thereof by applying electrical stimulation to the cardiomyocytes using an enzymatic biofuel cell, which comprises a step of applying the electrical stimulation to cardiomyocytes using a bio-anode which oxidizes an enzyme to generate electrons. According to the present invention, provided is a method for culturing cardiomyocytes without deteriorating the functions or decreasing stability even during a long-term culture process, by increasing the pulse rate of the cardiomyocytes by the electric stimulation through the bio-anode and the formation of an intercellular gap junction. COPYRIGHT KIPO 2017 ...

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14-01-2019 дата публикации

END2-배양액 분비물 분석을 통한 신규 저분자화합물을 이용한 인간전분화능줄기세포 유래 심근세포 분화 기술

Номер: KR0101938325B1
Автор: 문성환, 박순정, 정형민

... 본 발명은 지지세포의 대체제를 스크리닝하여 인간 전분화능 줄기세포로부터 심근세포로의 분화를 유도하는 방법에 대한 것이다. 따라서, 본 발명은 지지세포를 필요로 하지 않는 환경에서 줄기세포로부터 심근세포로 분화를 유도하는 방법을 제공한다. 종래에 END2 세포 같은 지지세포를 이용한 심근세포로의 분화 방법은 동물세포와의 오염 및 공배양시 심근세포만의 분리 및 정제가 어려운 단점이 있었으나, 본 발명은 지지세포를 저분자화합물로 대체하여 보다 안정적이고 재연성 있는 배양액을 개발하였다. 상기내용과 같이 인간전분화능줄기세포 유래 심근세포는 성체에서 확보 할 수 없는 심근세포를 확보할 수 있는 유일한 자원이며, 심혈관 질환 세포 치료제 및 신약 개발 자원으로 활용이 가능할 것이다.

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27-10-2016 дата публикации

2-AMINOETHYL METHACRYLATE-GRAFTED CHITOSAN COMPLEX FOR GENE DELIVERY USING RADIATION TECHNOLOGY, AND MANUFACTURING METHOD THEREOF

Номер: KR1020160124279A
Принадлежит:

The present invention relates to a gene transporter (AEMA-LMWC) without cytotoxicity, having improved gene-binding ability by increasing positive charges in comparison with existing chitosan, by introducing 2-aminoethyl methacrylate (AEMA) in low molecular weight chitosan (LMWC), which is a biocompatible substance, using a radiation irradiation technology. The AEMA-LMWC complex of the present invention can be applied as a gene transporter. COPYRIGHT KIPO 2016 ...

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23-12-2015 дата публикации

IMMUNOSTIMULATING COMPOSITION CONTAINING RECOMBINANT GIARDIA LAMBLIA BINDING IMMUNOGLOBULIN PROTEIN

Номер: WO2015194832A1
Принадлежит:

The present invention relates to an immunostimulating composition containing a recombinant Giardia lamblia binding immunoglobulin protein. The recombinant Giardia lamblia binding immunoglobulin protein of the present invention greatly improves immune activation through an immune reaction such as the cytokine production of dendritic cells and the maturation of dendritic cells, and thus can be useful as an immunostimulating preparation.

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07-09-2017 дата публикации

창상 질환 모델용 동물, 그 제조 방법 및 이를 이용한 창상 치료제의 효능 분석 방법

Номер: KR0101776236B1
Автор: 문성환, 정형민, 박순정
Принадлежит: 건국대학교 산학협력단

... 본 발명의 목적은, 창상 치료 연구의 모델로서 피부의 회복 과정이 인간 피부세포와 다른 마우스를 이용할 경우에 발생하는 한계점을 극복하고, 현실적이고 경제적인 방법으로 창상 치료 연구에 적용할 수 있는 창상 질환 모델용 동물을 제조하는 방법과 이를 이용한 창상 치료제 효능의 분석 방법을 제공하는 것에 관한 것이다. 따라서 본 발명은, 설치류 상피 특유의 수평적 구축 능력을 억제하기 위하여 창상의 표면과 수직으로 원통체를 삽입하고, 그 내부에 투입되어 창상의 표면에 얇은 막을 형성하는 천연 소재의 투과성 하이드로겔을 포함하는 창상 치료 모델을 제공한다. 본 발명에 따르면, 면역 반응을 일으키지 않기 때문에 면역을 억제하지 않은 동물 모델용 동물을 제조할 수 있고, 인체 창상의 환경과 더욱 유사한 조건의 모델용 동물을 이용하여 창상 치료제를 연구할 수 있는 효과가 있다. 또한, 하이드로겔을 원통체의 내부에 투입해 창상에 얇은 막을 형성함으로써 시료를 안정적으로 흡수시킬 수 있고, 임상 적용의 가능성을 높일 수 있는 효과가 있다.

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27-02-2018 дата публикации

폐암세포의 분리 및 증식 방법

Номер: KR0101832133B1

... 본 발명은 환자의 폐암조직으로부터 효과적인 폐암세포의 분리 및 증식을 위한 배양 조건 및 상기의 방법으로 배양된 폐암세포를 이용한 환자 특이적 암치료제의 스크리닝 방법에 관한 것으로, 보다 구체적으로 1) 환자로부터 분리한 폐암 조직을 지름 40 내지 100 μm의 크기로 절개하는 단계, 2) 상기 1)단계의 절개된 조직을 배양하는 단계, 3) 상기 2)단계의 배양된 세포에 디스파아제를 사용하여 폐암세포를 분리하는 단계, 4) 상기 3)단계의 폐암세포를 코팅물질이 코팅된 배양접시에서 무혈청 N2 배지로 배양하여 폐암세포만을 분리하여 배양하는 단계, 및 5) 상기 4)단계의 분리 배양된 폐암세포를 혈청 및 성장인자를 첨가한 배지에서 배양하여 증식시키는 단계를 포함하는 폐암조직으로부터 폐암세포를 분리 및 증식시키는 방법 및 상기 방법으로 제조된 폐암세포를 이용하여 환자 맞춤형 암치료제를 스크리닝하는 방법에 관한 것이다.

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