07-02-2017 дата публикации
Номер: KR1020170013836A
Автор:
LEE, JAE KWANG,
HAN, YOUNG HUE,
KIM, YUN TAE,
CHOI, DAE KYU,
MIN, JAE KI,
BAE, MI SEON,
YANG, HYUN MO,
KIM, DO HOON
Принадлежит:
The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof, a pharmaceutically acceptable salt thereof, a use thereof for preparation of a therapeutic drug, a pharmaceutical composition comprising the compound, a treatment method using the composition, and a method for preparing the compound. According to the present invention, the novel compound, optical isomer thereof or pharmaceutically acceptable salt thereof has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases, neoplasm, endocrine, nutritional and metabolic diseases, mental and behavioral disorders, nerve disorders, eye and appendage diseases, circulatory organ diseases, respiratory organ diseases, digestive organ diseases, skin and subcutaneous diseases, musculoskeletal and connective tissue diseases or congenital malformation, deformation and chromosome ...
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