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Небесная энциклопедия

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Применить Всего найдено 7. Отображено 7.
18-05-2017 дата публикации

DNA APTAMER SPECIFICALLY BINDING TO SURFACE OF LIVE BACTERIA OF ENTEROTOXIGENIC ESCHERICHIA COLI AND USE THEREOF

Номер: KR1020170054700A
Автор: KIM, YANG HOON, SHIN, WOO RI, LEE, SANG HEE, AHN, JI YOUNG
Принадлежит:

The present invention relates to a DNA aptamer which specifically binds to a surface of live bacteria of enterotoxigenic Escherichia coli (ETEC), and to detection of ETEC and/or diagnosis of diarrheal diseases caused by the ETEC. COPYRIGHT KIPO 2017 ...

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Номер записи: 1
19-07-2017 дата публикации

장독소형 대장균 생균의 표면에 특이적으로 결합하는 ＤＮＡ 앱타머 및 이의 용도

Номер: KR0101759399B1
Автор: 김양훈, 신우리, 이상희, 안지영
Принадлежит: 충북대학교 산학협력단

... 본 발명은 장독소형 대장균 (Enterotoxigenic Escherichia coli, ETEC) 생균의 표면에 특이적으로 결합하는 DNA 앱타머, 이를 이용한 장독소형 대장균의 검출 및 또는 장독소형 대장균에 의한 설사성 질환의 진단에 관한 것이다.

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Номер записи: 2
14-03-2017 дата публикации

DNA APTAMER SPECIFICALLY BINDING TO CYSTATIN B PROTEIN AND USES THEREOF

Номер: KR101716054B1
Автор: KIM, YANG HOON, UM, HYUN JU, SHIN, WOO RI, KIM, DAE GHON, CHO, SUNG JIN
Принадлежит: CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

The present invention relates to DNA aptamer specifically binding to cystatin B (CSTB) protein and to uses thereof, and more specifically, to DNA aptamer specifically binding to CSTB protein and to uses thereof, to a kit and a microarray for detecting CSTB using the same, to a method for providing information for diagnosis or prognosis judgment of cancers related to an increase of the expression of CSTB and to a composition for the same, and to a method for detecting CSTB protein. The DNA aptamer of the present invention can be used for effectively detecting CSTB protein or measuring the expression level thereof, and also can be used for the diagnosis or the prognosis judgment of cancers. COPYRIGHT KIPO 2017 (1) Aptamer-based sandwich elisa method (2) Antibody-based sandwich elisa method (A1,A2,A3) TMB substrate (B1,B2,B3) Oxidized TMB substrate (C1,C2) HRP-linked secondary antibody (D1,D2) CSTB detection antibody (E1,E2) HRP-linked CSTB binding aptamer 2 (F1,F2) CSTB specifically binding ...

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Номер записи: 3
14-03-2017 дата публикации

RNA APTAMER SPECIFICALLY BINDING TO NACA PROTEIN AND USES THEREOF

Номер: KR101716053B1
Автор: KIM, YANG HOON, SONG, MYUNG SUB, LEE, KYEONG AH, PARK, DAE YOUNG, SHIN, WOO RI, KIM, DAE GHON, CHO, SUNG JIN
Принадлежит: CHUNGBUK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION

The present invention relates to an RNA aptamer specifically binding to nascent polypeptide-associated complex alpha subunit (NACA) protein, and to uses thereof. The RNA aptamer of the present invention specifically binds to NACA protein which is a novel liver cancer biomarker, so as to be used for an early diagnosis of liver cancer, and prognosis decision. Besides, the RNA aptamer of the present invention suppresses the interaction between NACA protein and preS1 protein in HBV to suppress HBV infection, so as to be developed as medicines for treating liver cancer. COPYRIGHT KIPO 2017 ...

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Номер записи: 4
19-12-2019 дата публикации

FUSION PROTEIN BOUND TO CELL-PERMEABLE PEPTIDE, AND COMPOSITION COMPRISING FUSION PROTEIN OR CELL-PERMEABLE PEPTIDE AND EPITHELIAL CELL GROWTH FACTOR AS ACTIVE INGREDIENTS

Номер: WO2019240430A1
Автор: BAEK, Yi Yong, SHIN, Woo Ri, PARK, Si Eun, CHOI, Jun Sub, KOO, Hye Cheong
Принадлежит:

The present invention pertains to: a botulinum toxin, epithelial cell growth factor, or hexapeptide fusion protein bound to skin tissues and cell-permeable peptides, or an epithelial cell growth factor mixed with skin tissues and cell-permeable peptides; and a composition comprising same. The fusion protein or the epithelial cell growth factor mixed with cell-permeable peptides has increased cell permeability compared to protein by itself, and is thus useful for improving the condition of skin, treating wrinkles, relieving muscle tension, and treating wounds.

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Номер записи: 5
24-03-2023 дата публикации

세포 투과 펩티드 및 약제를 포함하는 창상 치료용 조성물

Номер: KR20230041318A
Автор: 백이용, 신우리, 박시은, 성보경, 김민정, 구혜정, 김재규, 정은경
Принадлежит:

... 세포 투과 펩티드 및 약제를 포함하는 창상 치료용 조성물에 관한 것으로, 상기 조성물은 약제의 세포 투과성이 증가되어 있으므로 창상 치료 용도로 유용하게 사용될 수 있다.

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Номер записи: 6
19-12-2019 дата публикации

PHARMACEUTICAL COMPOSITION COMPRISING FUSION PROTEIN OF CELL-PENETRATING PEPTIDE AND RPE65 FOR TREATMENT OF LEBER'S CONGENITAL AMAUROSIS

Номер: WO2019240431A1
Автор: SHIN, Woo Ri, BAEK, Yi Yong, CHOI, Jun Sub, KOO, Hye Cheong
Принадлежит:

The present invention relates to a composition comprising a fusion protein of a cell-penetrating peptide and Retinal Pigment Epithelium-specific 65 kDa (RPE65) as an effective ingredient. With RPE65 increased in cell penetrability, the composition can be advantageously used for treatment of Leber's congenital amaurosis.

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Номер записи: 7