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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 72. Отображено 72.
17-09-2018 дата публикации

METHOD FOR PRODUCING FRUIT-VEGETABLE JUICE CONTAINING PAPRIKA AND APPLE AND FRUIT-VEGETABLE JUICE PRODUCED THEREBY

Номер: KR1020180102258A
Автор: OH, DEOK GEUN
Принадлежит:

The present invention relates to a method for producing a fruit-vegetable juice containing paprika and apple, and a fruit-vegetable juice produced thereby. To this end, the fruit-vegetable juice prepared by mixing paprika and apple contains 5-10 wt% of paprika puree and 15-18 wt% of apple cloudy. By producing the fruit-vegetable juice using paprika and apple, it is possible to produce fruit-vegetable juices excellent in antioxidant activities while ensuring optimized functionality. COPYRIGHT KIPO 2018 (AA) Fruit-vegetable juice, fruit-vegetable concentrate (BB) Mixing process (CC) Stir (DD) Sterilization process (EE) Cooling process (FF) 10°C or lower (GG) Storage tank storage process (H1,H2) Filtering process (II) Magnet rod (JJ) Filling process (KK) Sealing and capping process (LL) Metal detector (MM) Product inspection, storage ...

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28-02-2013 дата публикации

D-PSICOSE 3-EPIMERASE MUTANT WITH IMPROVED THERMAL STABILITY, AND CONTINUOUS PRODUCTION OF D-PSICOSE USING SAME

Номер: WO2013027999A2
Принадлежит:

The present invention relates to a D-psicose 3-epimerase mutant of which the thermal stability is improved by substituting an amino acid of a specific sequence number. In addition, the present invention relates to a recombinant vector comprising the gene of the D-psicose 3-epimerase mutant, and a recombinant strain transformed with the recombinant vector. Further, the present invention relates to an immobilized reactor prepared using the enzyme mutant or the recombinant vector, and a method for producing D-psicose using the immobilized reactor.

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21-11-2019 дата публикации

COATING LIQUID COMPOSITION FOR CONTACT LENS, METHOD FOR MANUFACTURING SAME, AND METHOD FOR COATING USING SAME

Номер: WO2019221568A1
Принадлежит:

The present invention relates to a coating liquid composition for a contact lens, a method for manufacturing same, and a method for coating using same which can improve a surface slip property of a contact lens and form a coating layer having an improved hydrophilic property, the coating liquid composition for a contact lens according to the present invention being able to improve the surface slip property of the contact lens and form the coating layer having the improved hydrophilic property, thereby decreasing a friction coefficient of the contact lens so as to decrease damage to the eyelid and the cornea, performing a protective coating function for the eyelid and the surface of the cornea so as to increase comfort for the eye, and forming a stabilized tear layer.

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14-09-2017 дата публикации

OLEATE HYDRATASE 2 AND USE THEREOF

Номер: KR1020170104015A
Принадлежит:

The present invention relates to an oleate hydratase 2 derived from Stenotrophomonas maltophilia, and a method for producing, at high yield, hydroxy fatty acids from unsaturated fatty acid using recombinant Escherichia coli expressing the same. The method of the present invention enables production of hydroxy fatty acids at high yield and high rate compared to existing oleate hydratase. The hydroxy fatty acids produced thereby can be used in production of various spices, and can also be useful for producing emulsifiers and synthesizing polymers. COPYRIGHT KIPO 2017 ...

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22-03-2016 дата публикации

COMPOSITION AND METHOD FOR PREPARING GINSENOSIDE COMPOUND K BY MIXED ENZYMES OF THERMOSTABLE BETA-GLYCOSIDASE AND ALPHA-L-ARABINOFURANOSIDASE

Номер: KR1020160031245A
Принадлежит:

The present invention relates to a composition and a method for preparing ginsenoside compound K from an extract of red ginseng or fine roots of ginseng using thermostable beta-glycosidase (β-glycosidase) and alpha-L-arabinofuranosidase (α-L-arabinofuranosidase) enzymes. More specifically, the present invention relates to a composition and a method for preparing ginsenoside compound K, by using thermostable beta-glycosidase and alpha-L-arabinofuranosidase enzymes, which are derived from thermostable Sulfolobus solfataricus and Caldicellulosiruptor saccharolyticus strains, and exhibit stable activity even at high temperatures, so as to confirm the optimum concentration ratio between the two enzymes for raising the productivity of ginsenoside compound K, and rapidly regulate the reaction rate at high temperatures, thereby mass-producing the ginsenoside compound K from the extracts of red ginseng and fine roots of ginseng in a short time, and therefore can be favorably used for industrial ...

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12-09-2013 дата публикации

METHOD AND COMPOSITION FOR HIGH-YIELD PREPARATION OF GAMMA-DODECALACTONE FROM HYDROXY FATTY ACIDS

Номер: WO2013133497A1
Принадлежит:

The present invention relates to a method and composition for the high-yield preparation of gamma-dodecalactone using yeast. More particularly, the present invention relates to a method for the mass production of peach-flavored gamma-dodecalactone, which is a source material for food additives, by reacting 10-hydroxystearic acid using the yeast Waltomyces lipofer. The present invention also relates to a composition for the high-yield preparation of gamma-dodecalactone.

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13-10-2016 дата публикации

락토바실러스 에시도필러스 유래 13-리놀레산 수화효소에 의한 13-수산화 지방산의 생산 및 월토마이세스 리포퍼를 이용한 델타-데카락톤의 제조방법 및 그 조성물

Номер: KR0101666266B1
Автор: 오덕근, 강우리, 오혜진
Принадлежит: 건국대학교 산학협력단

... 본 발명은 락토바실러스 에시도필러스 유래 13-리놀레산 수화효소에 의한 13-수산화 지방산의 생산 및 월토마이세스 리포퍼를 이용한 델타-데카락톤의 제조방법 및 그 조성물에 관한 것으로, 본 발명에 따르면, 높은 특이성과 친환경적인 방법으로 산업품의 원료 물질인 13-수산화-9-옥타데세노익 산, 13-수산화-9,15-옥타데카디에노익 산, 13-수산화-6,9-옥타데카디에노익 산을 높은 수율로 생산할 수 있으며, 이렇게 생산된 13-수산화-9-옥타데세노익 산은 락톤(lactone) 의 합성 시작물질로서 유용하게 사용되며, 효모를 이용한 락톤생산방법은 종래의 화학적인 생산방법보다 환경 친화적이고 높은 특이성을 보이는 방법이다. 델타-락톤을 생산하기 위해 세포 자체 효소반응을 통한 생산방법으로 식품에 들어가는 원료 물질인 코코넛향이나 유제품의 향을 나타내는 델타-데카락톤을 높은 수율로 대량 생산할 수 있다.

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06-02-2020 дата публикации

COMPOSITION AND METHOD FOR PREPARATION OF DIHYDROXY FATTY ACID OR LIPID MEDIATOR BY USING COMBINED LIPOXYGENASE REACTIONS

Номер: WO2020027620A1
Принадлежит:

The present invention relates to a composition and a method for preparation of dihydroxy fatty acids or lipid mediators by using combined lipoxygenase reactions. According to the present invention, various dihydroxy fatty acids or lipid mediators including a novel material that has not yet been reported thus far can be produced using Mus musculus mouse-derived 8-lipoxygenase and Burkholderia thailandensis strain-derived 15-lipoxygenase.

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05-04-2018 дата публикации

COMPOSITION FOR PRODUCTION OF GINSENOSIDE COMPOUND K COMPRISING HIGH TEMPERATURE α-L-ARABINOFURANOSIDASE, AND METHOD FOR PREPARING GINSENOSIDE COMPOUND K

Номер: WO2018062904A1
Принадлежит:

Disclosed are a composition for production of ginsenoside compound K using a high temperature-β-glycosidase and a high temperature-α-L-arabinofuranosidase, and a method for preparing ginsenoside compound k. The composition for producing ginsenoside compound k and the method for preparing ginsenoside compound k according to one aspect of the present invention allow high temperature-β-glycosidase and high temperature-α-L-arabinofuranosidase to exhibit stable activity even at high temperatures, thereby increasing a reaction rate. The composition for producing ginsenoside compound k and the method for preparing ginsenoside compound k according to one aspect of the present invention allow a large quantity of ginsenoside compound k to be produced in a short time, thereby exhibiting an effect of producing a high yield, and thus can be utilized industrially.

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19-01-2012 дата публикации

MANNOSE 6-PHOSPHATE ISOMERASE MUTANT DERIVED FROM GEOBACILLUS THERMODENITRIFICANS, AND PRODUCTION METHOD OF L-RIBOSE USING SAME

Номер: WO2012008748A3
Принадлежит:

The present invention relates to a novel mannose 6-phosphate isomerase mutant enzyme, and a method for preparing L-ribose using the enzyme, and more specifically, to a mannose 6-phosphate isomerase mutant enzyme and a recombinant expression vector containing the corresponding gene, a microorganism transformed with the same, a method for the mass production of a mannose 6-phosphate isomerase mutant using the same, and a method for producing L-ribose at a high yield by using the mannose 6-phosphate isomerase mutant.

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31-12-2018 дата публикации

친수성 유기용매를 이용한 프룩토스 및 타가토스 혼합 조성물로부터 타가토스의 결정화 정제방법

Номер: KR0101933957B1
Автор: 오덕근, 이선화
Принадлежит: 건국대학교 산학협력단

... 본 발명은 (a) 프룩토스-타가토스 혼합 조성물을 농축하는 단계; (b) 상기 농축된 혼합 조성물과 유기용매를 혼합하여 혼합 용액을 제조하는 단계; (c) 상기 혼합 용액을 원심분리하여 상등액과 결정을 분리하는 단계; 및 (d) 상기 결정을 건조하는 단계를 포함하는 타가토스의 정제방법 및 상기 방법에 의해 정제된 타가토스에 관한 것이다.

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28-04-2011 дата публикации

MANNOSE 6-PHOSPHATE ISOMERASE, MUTANTS THEREOF, AND USE THEREOF

Номер: KR2011049409A2
Принадлежит:

The present invention relates to a novel mannose 6-phosphate isomerase enzyme, mutants thereof, and a method of manufacturing L-ribose with such mutant enzymes. More particularly, the invention relates to mannose 6-phosphate isomerase enzymes and variants thereof, recombinant expression vectors containing expression genes thereof, microorganisms transformed to express such genes, manufacturing methods for producing large quantities of mannose 6-phosphate isomerase enzyme and its mutants, and production methods for high yields of L-ribose made with the mannose 6-phosphate isomerase mutant enzymes.

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24-06-2015 дата публикации

METHOD FOR PRODUCING GAMMA-LACTONES AT HIGH YIELD FROM SAFFLOWER OIL BY MICROORGANISM, AND COMPOSITION THEREOF

Номер: KR1020150069682A
Автор: OH, DEOK KUN, JO, YE SEUL
Принадлежит:

The present invention relates to gamma-dodecelactone (γ-Dodecelactone) obtained from safflower oil, a method for producing gamma-dodecelactone (γ-Dodecelactone), and a composition thereof. More specifically, the present invention relates to a method for producing gamma-dodecelactone at a high-yield wherein a fatty acid is generated by treating microbial lipase in an oil, a hydroxy fatty acid is extracted by using stenotrophomonas nitritireducens bacteria, the hydroxy fatty acid is reacted with the yeast Candida boidinii, and gamma-dodecelactone is mass-produced at a high yield through an intracellular beta-oxidation (β-Oxidation). The present invention also relates to a method for producing additional gamma-dodecelactone (γ-Dodecelactone) and a composition thereof. According to the present invention, the production method using microorganisms is more environment-friendly and shows higher specificity than conventional chemical production methods. In addition, it is possible to produce the ...

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24-05-2018 дата публикации

APPARATUS FOR FORMING SUPPORT FOR CUP PACKAGING

Номер: KR1020180054014A
Принадлежит:

The present invention relates to an apparatus for forming a support for a cup, capable of providing the support to the cup by supplying a support paper to a movement path of the cup conveyed on a cup packaging apparatus. The apparatus includes: a support paper supply unit (300) which is disposed obliquely upward below a conveyor belt (220) for conveying a cup to be packaged and has an upper end adjacent to a terminal end of the conveyor belt (220) to supply a support paper (350) for the cup; a cup aligning unit for inserting the cup into each of a plurality of holes (351) formed in the support paper (350); and a support paper bending unit (400) which forms a cup support by bending a peripheral portion of the support paper (350) into which the cups are inserted. The support paper is automatically supplied during the process of packaging the cups in a bundle such that lower portions of the cups are inserted into the support paper, so that the cup can be packaged at inexpensive costs. The ...

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08-06-2018 дата публикации

베타-글라이코시다아제에 고활성 알파-엘-아라비노퓨라노시다아제 효소의 첨가에 의한 고수율 진세노사이드 컴파운드 K의 제조방법

Номер: KR0101855280B1
Автор: 오덕근, 신경철
Принадлежит: 건국대학교 산학협력단

... 본 발명은 설포로버스 솔파타리쿠스(Sulfolobussolfataricus) 유래의 β-글리코시다아제 및 딕티오클로무스 툴기둠(Dictyoglomusturgidum) 유래의 α-L-아라비노퓨라노시다아제를 이용하여 고수율의 진세노사이드 컴파운드 K를 생산하는 방법에 관한 것이다. 본 발명의 혼합 효소를 이용하였을 때, 인삼 추출물 내의 주요 진세노사이드를 진세노사이드 컴파운드 K(C-K)로 전환할 수 있다. 특히, 본 발명의 고온성 β-글리코시다아제 효소를 사용하면, 70℃ 이상의 고온에서도 반응을 수행할 수 있어 반응 배지에서 다양한 오염원을 배제시킬 수 있고, 동시에 주요 진세노사이드 Rb1, Rb2, Rc, Rd를 C-K로 전환함에 있어서 다른 부산물을 생산하지 않아 빠르고 특이적인 C-K 전환 반응이 가능하여 생산 수율을 증가시켜 고수율의 C-K를 생산할 수 있으므로, 본 발명의 β-글리코시다아제 및 α-L-아라비노퓨라노시다아제를 이용한 C-K 생산 방법은 산업적으로 유용하게 사용될 수 있다.

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18-09-2018 дата публикации

COFFEE MILK BEVERAGE AND MANUFACTURING METHOD THEREOF

Номер: KR1020180102873A
Принадлежит:

The present invention relates to a method for producing a coffee milk which has a substantially extended shelf life due to homogeneous emulsification of each component and to a coffee beverage made therefrom, wherein the method comprises the following steps: adding 0.15 to 0.25 wt% of a sucrose fatty acid ester-based emulsifier to a crude liquid containing 50 to 70 wt% of crude and a coffee extraction liquid, with respect to the total weight; and stirring the mixture at 3,000 to 7,000 rpm. COPYRIGHT KIPO 2018 ...

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24-10-2017 дата публикации

METHOD FOR PRODUCING TAGATOSE USING FRUCTOSE EPIMERASE DERIVED FROM DICTYOGLOMUS TURGIDUM AND COMPOSITION REQUIRED THEREFOR

Номер: KR1020170117860A
Принадлежит:

The present invention relates to a method for producing tagatose using fructose epimerase derived from Dictyomimis turgidum, and a composition required therefor. More specifically, the fructose epimerase of the present invention is used to effectively produce tagatose by epimerizing no.4 carbon of fructose in a medium, and thus can be used as an enzyme catalyst in a method for producing tagatose from the fructose. According to the present invention, the method for producing tagatose enables production of tagatose through an enzymatic reaction of a single process by using an environment-friendly enzyme catalyst, and requires only a simple enzyme immobilization process, thereby obtaining a high production effect compared with a conventional tagatose production method. In addition, the production costs are low by producing the tagatose through an enzymatic reaction of a single process from the fructose which is a cheap substrate, and thus a cost reduction effect can be obtained, thereby providing ...

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30-09-2015 дата публикации

A Manufacturing method for γ-lactones from safflower oil with a high yield by using microorganisms and composition therefor

Номер: KR0101556115B1
Автор: 오덕근, 조예슬
Принадлежит: 건국대학교 산학협력단

... 본 발명은 홍화유로부터 감마-도데케락톤(γ-Dodecelactone) 및 감마-도데카락톤(γ-Dodecelactone)의 생산방법 및 그 조성물에 관한 것으로, 더욱 상세하게는 본 발명은 오일에 미생물 리파아제를 처리하여 지방산을 생산한 뒤 세균 스테노트로포모나스 나이트리트리더센스(stenotrophomonasnitritireducens)를 이용하여 생산한 하이드록시 지방산을 추출한 하이드록시 지방산에 효모 캔디다 보이디니(Candida boidinii)를 반응시켜 세포내 베타-산화과정(β-Oxidation)을 통해 감마-도데케락톤을 고수율로 대량 생산하고, 감마-도데카락톤(γ-Dodecelactone)을 추가적으로 생산할 수 있는 방법 및 조성물에 관한 것이다. 본 발명에 따르면, 미생물을 이용한 생산방법은 종래의 화학적인 생산방법보다 환경 친화적이고 높은 특이성을 보이는 방법이다. 또한 천연에서 다량 획득할 수 있는 홍화오일에 단계적 미생물을 처리하여 식품첨가제의 원료물질인 복숭아향의 감마-도데케락톤을 높은 수율로 대량 생산할 수 있다.

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27-04-2018 дата публикации

METHOD FOR PRODUCING ALLOSE BY NOVEL L-RHAMNOSE ISOMERASE

Номер: KR1020180042973A
Принадлежит:

The present invention relates to a method for mass-producing, in high yield, allose that is a rare sugar having a pharmacological function of inhibiting the proliferation of cancer cells by L-rhamnose isomerase derived from novel Clostridium stercorarium, and suppressing organ damage caused by ischemia. The method of the present invention is to produce allose by reacting allulose with L-rhamnose isomerase proteins derived Clostridium thermocellum having D-allose isomerization activity. The method for producing allose of the present invention is environmentally friendly by using an enzyme, produces only allose in high specificity without production of additional sugars other than target sugar, and can be used as an efficient method for mass production of allose. COPYRIGHT KIPO 2018 ...

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30-07-2020 дата публикации

PRODUCTION OF DIHYDROXY FATTY ACID BY MEANS OF NOVEL LIPOXYGENASE DERIVED FROM BACTERIA

Номер: WO2020153782A2
Автор: OH, Deok Kun, LEE, Jin
Принадлежит:

The present invention relates to a novel lipoxygenase derived from bacteria, a method for producing a dihydroxy fatty acid by using same, and a composition for producing same. According to the present invention, it is possible to biosynthesize a dihydroxy fatty acid with high productivity and high yield in an environmentally friendly method that has not yet been reported. The dihydroxy fatty acid produced by means of the present invention can be utilized in various industrial fields such as medicine, food, and cosmetics, and is expected to be involved in various physiologically active functions in the body of animals including human beings, as a signal transmitter.

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26-10-2017 дата публикации

METHOD TO STERILIZE CONTACT LENS PACKAGE SOLUTION

Номер: KR101790612B1
Принадлежит: INTEROJO INC.

The present invention relates to a method to sterilize a contact lens package solution. The method, capable of sterilizing a contact lens package solution during a process of inserting a package solution and a contact lens into a blister pack and packing the blister pack with a lead paper, comprises: a first step of emitting UV-C directly to the package solution; a second step of emitting UV-C directly to the contact lens; a third step of inserting the package solution and the contact solution into the blister pack and then emitting UV-C directly to the upper part of the blister pack; and a fourth step of emitting UV-C directly to an adhesive surface of the lead paper combined with the blister pack. As such, the present invention is capable of enabling the effective quality management of a contact lens as well as minimizing fungi and bacteria in a package solution, which are attached to the surface of the contact lens, thereby improving preservability and significantly reducing ocular diseases ...

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17-09-2018 дата публикации

METHOD FOR PRODUCING POUCH PACKAGE INTEGRATED WITH SCRAPER DEVICE AND PACKAGE PRODUCT THEREOF

Номер: KR1020180102257A
Принадлежит:

The present invention relates to a method for producing a pouch package integrated with a scraper device for a stick-type pouch packaging, which includes the steps of providing a bar-shaped scraper device (10) at a predetermined position in a lower portion (32) on the outer side of wrapping paper, through a binding means (20) and providing a support protrusion (40) capable of preventing the scraper device (10) from being separated, and a package product thereof. More particularly, in a stick-type pouch packaging for containing viscous liquid contents (34), the scraper device (10), which has a predetermined shape to squeeze and discharge contents while pressing both left and right sides of the wrapping paper, is integrally provided on the outer side of the wrapping paper (30) in order to prevent residuals in the package upon intake. In addition, the support protrusion (40) is formed at a predetermined position in the lower portion (32) of the wrapping paper to prevent the scraper device ...

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21-06-2017 дата публикации

OLEATE HYDRATASE GENE, EXPRESSION VECTOR CONTAINING GENE, AND TRANSFORMANT TRANSFORMED BY VECTOR

Номер: KR101749429B1

The present invention relates to an oleate hydratase gene converting unsaturated fatty acid into 10-hydroxystearic acid, an expression vector of the gene, and a recombinant vector and a transformant introduced with the gene. Oleate hydratase of the present invention uses various unsaturated fatty acids including oleic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, palmitoleic acid, etc. as a substrate to convert 10-hydroxystearic acid only into a final product, thereby producing 10-hydroxystearic acid in an eco-friendly way and with high yield without generating byproducts. COPYRIGHT KIPO 2017 ...

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11-08-2015 дата публикации

Method for the production of 5,8-dihydroxylinoleic acid by diol synthase from Aspergillus nidulans and composition therefor

Номер: KR0101543297B1
Автор: 오덕근, 서민주
Принадлежит: 건국대학교 산학협력단

... 본 발명은 5,8-이수산화 리놀레익 산(5,8-Dihydroxylioleic acid)의 생산방법 및 그 조성물에 관한 것으로 산물의 정확한 명칭은 5,8-dihydroxy-9,12(Z,Z)-octadecadienoic acid이며, 더욱 상세하게는아스퍼질러스 니둘란스(Aspergillus nidulans) 균 유래의 이수산화 합성효소(Diol synthase)를 이용하여 리놀레익산 (linoleic acid) 반응조건을 최적화하고 최적화된 조건에서 반응시켜 5,8-이수산화 리놀레익 산을 고 수율로 생산하는 방법 및 그에 필요한 조성물에 관한 것이다. 본 발명에 따르면, 높은 특이성과 친환경적인 방법으로 5,8-이수산화 리놀레익 산을 높은 수율로 생산할 수 있으며, 이렇게 생산된 5,8-이수산화 리놀레익 산은 다양한 산업분야의 원료물질로 사용될 수 있다.

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20-06-2018 дата публикации

METHOD FOR PRODUCING CAPSULE CONTAINING MILK AND CORN SILK EXTRACT, AND CAPSULE PRODUCED THEREBY

Номер: KR1020180066909A
Принадлежит:

The present invention relates to a method for producing a capsule containing milk and a corn silk extract, comprising the following steps: (a) preparing a mixture by mixing corn silk extract powder and alginate with milk; and (b) dropping the mixture into a solution containing a polyvalent cation. According to the present invention, it is possible to prevent accumulation of fat due to absorption of fat components contained in the milk using the corn silk extract encapsulated in the capsule, and a user can feel as if the user drinks low fat milk without artificially removing fat contained in the milk. Further, by developing new milk beverages in a form of capsules, it is possible to increase milk consumption. COPYRIGHT KIPO 2018 ...

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13-06-2016 дата публикации

A ALDOLASE MUTANT AND A D-TAGATOSE PRODUCTION METHOD BY USING THE SAME

Номер: KR0101627921B1
Автор: 오덕근, 홍승혜, 이선화
Принадлежит: 건국대학교 산학협력단

... 본 발명은 알돌레이즈 돌연변이체 및 이를 이용한 타가토스 생산 방법에 관한 것으로 본 발명의 기술은 미생물로부터 얻은 효소를 이용하므로 환경 친화적이며, 간단한 효소 고정화 과정만을 필요로 하고, 종래 타가토스 생산과 비교하여 기질에 있어서는 단가가 낮은 기질을 사용하고, 수율에 있어서는 현저하게 높기 때문에 생산경비를 크게 줄이는 한편 생산 효과를 극대화할 수 있는 효과가 있다.

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13-07-2017 дата публикации

BIOCONVERSION PROCESS USING OLEIC ACID HYDRATASE 2

Номер: WO2017119576A1
Принадлежит:

The present invention relates to a bioconversion process for producing a heavy chain fatty acid and a heavy chain omega-hydroxy fatty acid from a long-chain unsaturated fatty acid substrate by using a novel oleic acid hydratase 2; a novel oleic acid hydratase 2 used for the process; a polynucleotide for coding the oleic acid hydratase 2; and a method for increasing the proportion of water-soluble expression to the total expression level of a target protein. When using the oleic acid hydratase 2 and the method for increasing the expression proportion of a water-soluble protein provided by the present invention, it is possible to increase the efficiency of a conventional bioconversion process for producing a heavy chain fatty acid and a heavy chain omega-hydroxy fatty acid from an unsaturated long chain fatty acid, and therefore the present invention can be widely used for the development of a more effective bioconversion process.

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30-09-2015 дата публикации

METHOD FOR PRODUCING 13-HYDROXY FATTY ACID BY USING 13-LINOLEATE HYDRATASE DERIVED FROM LACTOBACILLUS ACIDOPHILUS AND δ-DECALACTONE BY USING WALTOMYCES LIPOFER, AND COMPOSITION THEREOF

Номер: KR1020150108809A
Принадлежит:

The present invention relates to a method for producing 13-hydroxy fatty acid by using 13-linoleate hydratase derived from lactobacillus acidophilus and δ-decalactone by using waltomyces lipofer, and a composition thereof. According to the present invention, 13-hydroxy-9-octadecenoic acid, 13-hydroxy-9,15-octadecenoic acid, and 13-hydroxy-6,9-octadecenoic acid, which are raw materials of a product, can be produced at a high yield in an environmentally-friendly method having high specificity. The produced 13-hydroxy-9-octadecenoic acid is used as a synthesis initiator for lactone, and a method for producing lactone by using yeast is more environmentally-friendly and exhibits higher specificity, compared to a conventional chemical production method. The δ-decalactone releasing a flavor of coconut or a dairy product, which is a raw material to be used for food, can be mass-produced at a high yield in a production method using a cell enzyme reaction to produce δ-lactone. COPYRIGHT KIPO 2015 ...

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31-08-2018 дата публикации

CLOCK TREE SYNTHESIS METHOD CONSIDERING AGING PHENOMENON AND VOLTAGE VARIATION

Номер: KR1020180097314A
Автор: KIM, JU HO, OH, DEOK KEUN
Принадлежит:

According to an embodiment of the present invention, a clock tree synthesis method considering an aging phenomenon and a voltage variation includes the steps of: setting a gating probability of each buffer to constitute a clock tree; calculating a signal probability of each buffer based on the gating probability; calculating a power supply voltage to be supplied to the buffer according to the calculated signal probability; and inserting the buffer by determining the position of the buffer. Accordingly, the present invention can prevent clock skew. COPYRIGHT KIPO 2018 (AA) Start (BB) End (S210) Inputting clock sync information (S220) Generating a buffer embedding area and performing clock sync clustering (S230) Setting a gating probability of each buffer to constitute a clock tree (S240) Calculating a signal probability of each buffer based on the gating probability (S250) Calculating a power supply voltage to be supplied to the buffer according to the calculated signal probability (S252 ...

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28-06-2018 дата публикации

HEXURONATE C4-EPIMERASE VARIANT HAVING ENHANCED ABILITY FOR PRODUCING TAGATOSE FROM FRUCTOSE

Номер: KR1020180071533A
Принадлежит:

The present invention relates to a hexuronate C4-epimerase variant having an enhanced ability for producing tagatose from fructose in which at least one of 59th, 128th, 296th, 300th or 334th amino acids of the amino acid sequence of SEQ ID NO: 1 is substituted, and uses thereof. The use of the hexuronate C4-epimerase variant of the present invention can produce tagatose in a simple process, and thus can be usefully used industrially. COPYRIGHT KIPO 2018 ...

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30-08-2012 дата публикации

METHOD FOR PREPARING LACTULOSE FROM LACTOSE USING CELLOBIOSE 2-EPIMERASE OR N-ACETYL GLUCOSAMIN 2-EPIMERASE

Номер: WO2012115390A3
Принадлежит:

The present invention relates to a method for preparing lactulose from lactose using cellobiose 2-epimerase or N-acetyl glucosamin 2-epimerase, and more specifically relates to a production method for obtaining lactulose using recombinant expression vectors containing these genes, microorganisms transformed thereby, and enzymes.

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23-07-2018 дата публикации

컵용기 포장장치

Номер: KR0101867992B1

... 본 발명은 컵용기 포장장치에 관한 것으로, 내용물이 충전된 컵용기들의 이송되는 컵용기들을 정렬하는 정렬부(100), 상기 정렬부(100)에서 정렬된 컵용기의 이동 경로에 컵용기들에 받침대를 제공하기 위한 홀(351)들이 형성된 간지(350)를 공급하여 컵용기들의 하부를 간지(350)에 형성된 홀(351)에 각각 삽입하는 간지 공급부(300), 상기 컵용기들이 각각 홀에 삽입된 간지들의 주변부를 하방 절곡하여 받침대를 형성하는 간지 절곡부(400), 받침대에 삽입된 상태의 컵용기들을 포장박스에 포장하기 위해 포장공정으로 이송하는 포장진입부(500), 및 상기 포장진입부에 이송된 컵용기들을 포장박스에 넣어 포장하는 포장부(600)를 포함하여 구성됨으로써, 컵용기들을 묶음 형태로 포장하는 공정중에 이송되는 컵용기들의 하부가 삽입되도록 받침대용으로 간지를 제공하는 과정을 자동화함으로써 받침대가 제공된 컵용기 포장을 효율적으로 수행할 수 있어, 컵용기 포장 생산성을 향상시키고, 이러한 컵용기들을 받침대로 안정되게 유지되게 하여 컵용기 운송 과정에서의 흔들림에도 컵용기들이 넘어지지 않게 되어 컵용기 운송에서의 파손과 같은 문제점이 발생되지 않는 효과가 있다.

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24-05-2018 дата публикации

APPARATUS FOR PACKAGING CUPS

Номер: KR1020180054015A
Принадлежит:

The present invention relates to a cup packaging apparatus. The cup packaging apparatus includes: an aligning unit (100) for aligning cups which are conveyed and filled with contents; a support paper supply unit (300) for supplying a support paper (350) having holes (351) to a movement path of the cups aligned by the aligning unit (100) such that lower portions of the cups are inserted into the holes (351) formed in the support paper (350); a support paper bending unit (400) for bending a peripheral portion of the support paper having the holes into which the cups are inserted; a packaging entrance section (500) for conveying the cups inserted into the support paper into a packaging process for packaging the cups in a package box; and a packaging unit (600) for packaging the cups conveyed to the packaging entrance section into a packaging box. The support paper is automatically supplied during the process of packaging the cups in a bundle such that lower portions of the cups are inserted ...

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19-06-2015 дата публикации

METHOD FOR PREPARING 5,8-DIHYDROXYLINOLEIC ACID OF ASPERGILLUS NIDULANS AT HIGH YIELD AND COMPOSITION REQUIRED THEREFOR

Номер: KR1020150068099A
Автор: OH, DEOK KUN, SEO, MIN JU
Принадлежит:

The present invention relates to method for preparing 5,8-dihydroxylioleic acid and a composition thereof wherein an exact name of the composition is 5,8-dihydroxy-9,12(Z,Z)-octadecadienoic acid. More specifically, the invention relates to a method for preparing 5,8-dihydroxylioleic acid at a high yield by using diol synthase originated from aspergillus nidulans to optimize reaction conditions of linoleic acid, and to a composition required therefor. According to the present invention, it is possible to prepare 5,8-dihydroxylioleic acid at a high yield with a highly specific and a highly environment-friendly method and 5,8-dihydroxylioleic acid prepared thereby can be used as a raw material in various industries. COPYRIGHT KIPO 2015 ...

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22-06-2018 дата публикации

컵용기 포장용 받침대 형성장치

Номер: KR0101867993B1

... 본 발명은 컵용기 포장장치에서 이송되는 컵용기들의 이동 경로에 받침대용 간지를 공급하여 컵용기들에 받침대를 제공하는 컵용기 받침대 형성장치에 관한 것으로, 포장할 컵용기들을 이송하는 컨베이어벨트(220) 하측에 경사지게 상방으로 설치되어 상단이 상기 컨베이어벨트(220)의 종단부에 인접하게 배치되고, 컵용기 받침대용 간지(350)를 공급하는 간지 공급부(300)와 상기 간지(350)에 형성된 복수개의 홀(351)들 각각으로 컵용기들을 삽입하는 컵용기 배치기 및 상기 컵용기들이 홀(351)들에 삽입 배치된 간지(350)의 주변부를 절곡하여 컵용기 받침대로 형성하는 간지 절곡부(400)를 포함하는 것을 특징으로 하여 구성됨으로써, 컵용기들을 묶음 형태로 포장하는 공정중에 이송되는 컵용기들의 하부가 삽입되도록 받침대용으로 간지를 제공하는 과정을 자동화함으로써 받침대가 제공된 컵용기 포장을 저렴하게 제공할 수 있으며, 컵용기 포장 생산성을 향상시키고, 이러한 컵용기들을 받침대로 안정되게 유지되게 하여 컵용기 운송 과정에서의 흔들림에도 컵용기들이 넘어지지 않게 되어 컵용기 운송에서의 파손과 같은 문제점이 발생되지 않는 효과가 있다.

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30-08-2012 дата публикации

METHOD FOR PREPARING LACTULOSE FROM LACTOSE USING CELLOBIOSE 2-EPIMERASE OR N-ACETYL GLUCOSAMIN 2-EPIMERASE

Номер: WO2012115390A9
Принадлежит:

The present invention relates to a method for preparing lactulose from lactose using cellobiose 2-epimerase or N-acetyl glucosamin 2-epimerase, and more specifically relates to a production method for obtaining lactulose using recombinant expression vectors containing these genes, microorganisms transformed thereby, and enzymes.

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16-02-2016 дата публикации

METHOD FOR PRODUCING 13-HYDROXYLIOLEIC ACID IN HIGH YIELD BY BURKHOLDERIA THAILANDENSIS-DERIVED LIPOXIDASE AND COMPOSITION THEREOF

Номер: KR1020160017427A
Принадлежит:

The present invention relates to a method for producing 13-hydroxylioleic acid and a composition thereof. More specifically, the present invention relates to a method for producing 13-hydroxylioleic acid in a high yield using Burkholderia thailandensis-derived lipoxygenase by optimizing a reaction condition of linoleic acid so as to carry out a reaction under an optimized condition. According to the present invention, production of 13-hydroxylioleic acid in high yield in an eco-friendly way with high specificity. In addition, the 13-hydroxylioleic acid produced thereby can be used in various industrial fields as a raw material. COPYRIGHT KIPO 2016 ...

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27-02-2019 дата публикации

항균력을 갖는 콘택트렌즈용 식염수 및 이의 제조방법

Номер: KR0101952576B1
Принадлежит: 주식회사 인터로조

... 본 발명은 감초의 성분인 천연물질의 글리시리진산 암모늄염을 유효성분으로 제조되는 항균력을 갖는 콘택트렌즈용 식염수 및 이의 제조방법에 관한 것으로 보다 상세하게는 정제수 1000g, 염화나트륨 5~10g, 붕산 1~5g, 붕사 0.01~0.2g을 혼합하여 제1혼합물을 생성하는 제1단계와 상기의 제1혼합물 99.9~99.99중량%에 2mM의 글리시리진산 암모늄염 0.01~0.1중량%를 넣고 30분간 300rpm으로 교반하는 제2단계와 상기의 제2단계가 완료된 후 글리시리진산 암모늄염 농도에 따른 세균 항균력을 검사하는 검사단계인 제3단계의 제조방법으로 구성되어 항생제처럼 내성을 지니지 않아 부작용이 나타나지 않고 각막 손상 및 결막에 자극이 거의 없으며 낮은 농도로도 세균과 진균에 대한 높은 항균력을 갖는 효과가 있는 항균력을 갖는 콘택트렌즈용 식염수 및 이의 제조방법에 관한 것이다.

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13-07-2018 дата публикации

Preparation method of ginsenoside compound K using a novel thermostable β-glucosidase

Номер: KR0101878392B1
Автор: 오덕근, 신경철, 김태훈
Принадлежит: 건국대학교 산학협력단

... 본 발명은 칼디셀룰로시럽터 베시(Caldicellulosiruptor bescii) 균주로부터 유래한 고온성 β-글리코시다아제(β-glycosidase) 효소를 이용하여 고수율의 진세노사이드 컴파운드 K를 생산하는 방법에 관한 것이다. 본 발명의 β-글리코시다아제 효소를 이용하였을 때, 인삼 추출물 내의 주요 진세노사이드를 진세노사이드 컴파운드 K(C-K)로 전환할 수 있다. 특히, 본 발명의 고온성 β-글리코시다아제 효소를 사용하면, 70℃ 이상의 고온에서도 반응을 수행할 수 있어 반응 배지에서 다양한 오염원을 배제시킬 수 있고, 동시에 주요 진세노사이드 Rb1, Rb2, Rc, Rd를 C-K로 전환함에 있어서 다른 부산물을 생산하지 않아 빠르고 특이적인 C-K 전환 반응이 가능하여 생산 수율을 증가시켜 고수율의 C-K를 생산할 수 있으므로, 본 발명의 칼디셀룰로시럽터 베시 유래의 고온성 β-글리코시다아제 효소를 이용한 C-K 생산 방법은 산업적으로 유용하게 사용될 수 있다.

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07-10-2016 дата публикации

다양한 미생물 유래의 과당 1,6-이인산 알돌레이즈 및 이를 이용한 과당 6-인산으로부터 타가토스 6-인산으로의 효소 전환 방법

Номер: KR0101663358B1
Автор: 오덕근, 홍승혜, 이선화
Принадлежит: 건국대학교 산학협력단

... 본 발명은 다양한 미생물 유래의 과당 1,6-이인산 알돌레이즈 및 이를 이용한 과당 6-인산으로부터 타가토스 6-인산으로의 효소 전환 방법에 관한 것이다.

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23-07-2018 дата публикации

METHOD FOR CRYSTALLIZATION AND PURIFICATION OF TAGATOSE FROM MIXED COMPOSITION OF FRUCTOSE AND TAGATOSE USING HYDROPHILIC ORGANIC SOLVENT

Номер: KR1020180083505A
Принадлежит:

The present invention relates to a purification method of fructose, which comprises the following steps: (a) concentrating a mixed composition of fructose and tagatose; (b) mixing the concentrated mixed composition with an organic solvent to prepare a mixed solution; (c) separating a supernatant and crystals by centrifuging the mixed solution; and (d) drying the crystals, and to the fructose purified by the method. The present invention relates to the method for separating and purifying pure tagatose from the mixed composition of the fructose and tagatose, in which a separation and purification process of the mixed composition is repeated to separate high-purity tagatose with high yield. COPYRIGHT KIPO 2018 ...

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17-03-2016 дата публикации

COMPOSITION FOR PREPARING GINSENOSIDE COMPOUND K BY MIXED ENZYMES OF THERMOSTABLE BETA-GLYCOSIDASE AND ALPHA-L-ARABINOFURANOSIDASE, AND PREPARATION METHOD

Номер: WO2016039575A1
Принадлежит:

The present invention relates to a composition for preparing ginsenoside compound K from a red ginseng extract or fine root ginseng extract by using thermostable beta-glycosidase (β-glycosidase) and alpha-L-arabinofuranosidase (α-L-arabinofuranosidase) enzymes, and a preparation method. More specifically, the present invention relates to: a composition for preparing ginsenoside compound K, by using thermostable beta-glycosidase and alpha-L-arabinofuranosidase enzymes, which are derived from a thermophilic Sulfolobus solfataricus strain and Caldicellulosiruptor saccharolyticus strain and exhibit stable activity even at high temperatures, so as to confirm the optimal concentration ratio of two types of enzymes for raising ginsenoside compound K productivity and rapidly regulate the reaction rate at high temperatures, thereby mass producing the ginsenoside compound K from red ginseng and fine root ginseng extracts in a short time, so as to be industrially useful; and a preparation method.

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15-07-2015 дата публикации

FRUCTOSE 1,6-BISPHOSPHATE ALDOLASES FROM VARIOUS MICROORGANISMS AND ENZYMATIC CONVERSION METHOD OF TAGATOSE 6-PHOSPHATE FROM FRUCTOSE 6-PHOSPHATE USING SAME

Номер: KR1020150081823A
Принадлежит:

The present invention relates to a fructose 1,6-bisphosphate aldolases from various microorganisms and an enzymatic conversion method of tagatose 6-phosphate from fructose 6-phosphate using the same. COPYRIGHT KIPO 2015 ...

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03-04-2018 дата публикации

푸사리움 모닐리포르메 바 써브글루티난스의 세포외 효소를 이용한 진세노사이드 알지원으로부터 진세노사이드 에프원의 생산방법

Номер: KR0101844975B1
Принадлежит: (주)아모레퍼시픽

... 본 발명은 미생물 푸사리움 모닐리포르메 바 써브글루티난스(Fusarium moniliforme var. subglutinans)의 세포외 효소를 사용하여 희귀 진세노사이드 F1(Ginsenoside F1)의 제조방법에 관한 것으로, 더욱 상세하게는 자낭균류 곰팡이인 모닐리포르메 바 써브글루티난스 KCTC 6149의 배양액 중의 상등액의 효소를 사용하여 기질로서 진세노사이드 Rg1(Ginsenoside Rg1)과 반응용매 중에서 반응시켜 진세노사이드 F1을 제조하는 방법을 제공한다.

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31-05-2017 дата публикации

GENE ENCODING OPTIMIZED RIBOSE 5-PHOSPHATE ISOMERASE, MICROORGANISM INCLUDING SAME, AND METHOD FOR PRODUCING ALLOSE USING SAME

Номер: KR1020170059828A
Принадлежит:

The present invention relates to a gene encoding optimized ribose 5-phosphate isomerase, a microorganism including the same, and a method for producing allose using the same. According to the present invention, compared to expression of existing polynucleotide sequence for allose, the gene of the present invention secures excellent expression and allose conversion rates, thereby enabling mass-production of allose at relatively high yield. COPYRIGHT KIPO 2017 ...

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21-06-2017 дата публикации

하이드록시 지방산으로부터 고수율의 감마-도데카락톤의 제조방법 및 그 조성물

Номер: KR0101749776B1
Автор: 오덕근, 주영철
Принадлежит: 건국대학교 산학협력단

... 본 발명은 효모를 이용한 고수율의 감마-도데카락톤의 제조방법 및 그 제조용 조성물에 관한 것으로서, 보다 상세하게는 효모 월토마이세스 리포퍼를 이용하여 10-하이드록시스테아르산을 반응시켜 식품첨가제의 원료 물질인 복숭아향의 감마-도데카락톤을 대량 생산하는 방법 및 그 제조용 조성물에 관한 것이다.

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30-07-2018 дата публикации

Hexuronate C4-epimerase variant having improved productivity of tagatose from fructose

Номер: KR0101883351B1
Автор: 신홍식, 오덕근, 김민지
Принадлежит: (주)케비젠, 신홍식

... 본 발명은 서열번호 1의 아미노산 서열 중 59번째, 128번째, 296번째, 300번째 또는 334번째 아미노산 중 어느 하나 이상의 아미노산이 치환된 것을 특징으로 하는 과당(fructose)에서 타가토스(tagatose)를 생산하는 능력이 개선된 헥수론산 C4-에피머화 효소(hexuronate C4-epimerase) 변이체 및 이의 용도에 관한 것으로, 본 발명의 헥수론산 C4-에피머화 효소 변이체를 이용하면 간단한 공정으로 타가토스를 생산할 수 있으므로, 산업적으로 유용하게 활용될 수 있을 것이다.

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03-12-2015 дата публикации

PSICOSE EPIMERASE AND PSICOSE PRODUCTION METHOD USING SAME

Номер: WO2015182937A1
Принадлежит:

The present invention provides a novel psicose epimerase derived from Flavonifractor plautii and capable of converting fructose to psicose. The novel psicose epimerase, according to the present invention, possesses an activity producing psicose by epimerizing the carbon-3 position of fructose, and has maximal activity for the conversion of fructose to psicose at a relatively high temperature and a pH less than or equal to neutral, has excellent thermal stability, and can mass produce psicose from fructose in a high yield for a short amount of time. Therefore, the psicose epimerase according to the present invention is advantageous in the industrial production of psicose, and the psicose produced thereby can be utilized in the functional sugar industry and as materials for health food, medicine, cosmetics, and the like.

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28-04-2011 дата публикации

MANNOSE 6-PHOSPHATE ISOMERASE, MUTANTS THEREOF, AND USE THEREOF

Номер: WO2011049409A3
Принадлежит:

The present invention relates to a novel mannose 6-phosphate isomerase enzyme, mutants thereof, and a method of manufacturing L-ribose with such mutant enzymes. More particularly, the invention relates to mannose 6-phosphate isomerase enzymes and variants thereof, recombinant expression vectors containing expression genes thereof, microorganisms transformed to express such genes, manufacturing methods for producing large quantities of mannose 6-phosphate isomerase enzyme and its mutants, and production methods for high yields of L-ribose made with the mannose 6-phosphate isomerase mutant enzymes.

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25-08-2016 дата публикации

BOOSTER SUCTION TYPE BEVERAGE CONTAINER

Номер: KR101651225B1
Автор: OH, DEOK GEUN
Принадлежит: SEOUL F&B CO., LTD.

The present invention relates to a booster suction type beverage container. According to the present invention, the booster suction type beverage container comprises a container main body (110), a container lid (120) opening or closing the container main body (110), and a booster piston (130) provided to adhere to an inner circumferential surface (110a) of the container′s main body (110). The booster piston (130) includes a piston body (131) adhering to the inner circumferential surface (110a) of the container main body (110), and a booster unit (132) extending upward from the piston body (131), wherein the piston body (131) is folded toward the inside of a cavity (Ca) of the piston body (131) and is unfolded upward when initial suction force is applied from the outside. The booster unit (132) is unfolded upward to forcibly discharge contents upward from a container′s main body (110), and the booster piston (130) moves upward while adhering to an inner circumferential surface (110a) to ...

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30-08-2012 дата публикации

METHOD FOR PREPARING LACTULOSE FROM LACTOSE USING CELLOBIOSE 2-EPIMERASE OR N-ACETYL GLUCOSAMIN 2-EPIMERASE

Номер: WO2012115390A2
Принадлежит:

The present invention relates to a method for preparing lactulose from lactose using cellobiose 2-epimerase or N-acetyl glucosamin 2-epimerase, and more specifically relates to a production method for obtaining lactulose using recombinant expression vectors containing these genes, microorganisms transformed thereby, and enzymes.

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22-11-2018 дата публикации

COMPOSITION FOR PRODUCING HYDROXYFATTY ACIDS, HEPOXILINS, OR TRIOXILINS

Номер: WO2018212624A1
Автор: OH, Deok Kun, AN, Jung Ung
Принадлежит:

The present invention relates to a 11-lipoxygenase consisting of the amino acid sequence represented by SEQ ID NO: 1; or a composition for producing 11-hydroxyfatty acid, hepoxilin D3, or trioxilin D3, comprising the 11-lipoxygenase and an epoxide hydrolase consisting of the amino acid sequence represented by SEQ ID NO: 2; and a method for producing 11-hydroxyfatty acid, hepoxilin D3, or trioxilin D3, using the same composition. In addition, the present invention relates to a 12-lipoxygenase consisting of the amino acid sequence represented by SEQ ID NO: 5; or a composition for producing 12-hydroxyfatty acid, hepoxilin B, or trioxilin B, comprising the 12-lipoxygenase and an epoxide hydrolase consisting of the amino acid sequence represented by SEQ ID NO: 2; and a method for producing 12-hydroxyfatty acid, hepoxilin B, or trioxilin B, using the same composition.

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26-10-2015 дата публикации

A METHOD FOR THE PRODUCTION OF 13-HYDROXY-FATTY ACID BY USING LACTOBACILLUS ACIDOPHILUS 13-LINOLEATE HYDRATASE AND δ-DECALACTONE FROM THE HYDROXY FATTY ACID BY USING WALTOMYCES LIPOFER AND A COMPOSITION THEREFOR

Номер: KR0101563307B1
Автор: 오덕근, 오혜진, 강우리
Принадлежит: 건국대학교 산학협력단

... 본 발명은 락토바실러스 에시도필러스 유래 13-리놀레산 수화효소에 의한 13-수산화 지방산의 생산 및 월토마이세스 리포퍼를 이용한 델타-데카락톤의 제조방법 및 그 조성물에 관한 것으로, 본 발명에 따르면, 높은 특이성과 친환경적인 방법으로 산업품의 원료 물질인 13-수산화-9-옥타데세노익 산, 13-수산화-9,15-옥타데카디에노익 산, 13-수산화-6,9-옥타데카디에노익 산을 높은 수율로 생산할 수 있으며, 이렇게 생산된 13-수산화-9-옥타데세노익 산은 락톤(lactone) 의 합성 시작물질로서 유용하게 사용되며, 효모를 이용한 락톤생산방법은 종래의 화학적인 생산방법보다 환경 친화적이고 높은 특이성을 보이는 방법이다. 델타-락톤을 생산하기 위해 세포 자체 효소반응을 통한 생산방법으로 식품에 들어가는 원료 물질인 코코넛향이나 유제품의 향을 나타내는 델타-데카락톤을 높은 수율로 대량 생산할 수 있다.

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14-12-2018 дата публикации

노화현상 및 전압변이를 고려한 클럭 트리 합성 방법

Номер: KR0101929440B1
Автор: 김주호, 오덕근
Принадлежит: 서강대학교산학협력단

... 본 발명의 실시 예에 따른 노화현상 및 전압변이를 고려한 클럭 트리 합성 방법은, 클럭 트리를 구성할 각 버퍼의 게이팅 확률을 설정하는 단계와, 게이팅 확률에 기반하여 각 버퍼의 시그널 확률을 산출하는 단계와, 산출된 시그널 확률에 따라 버퍼에 공급할 전원전압을 산출하는 단계 및 버퍼의 위치를 결정하여 버퍼를 삽입하는 단계를 포함한다.

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19-01-2012 дата публикации

MANNOSE 6-PHOSPHATE ISOMERASE MUTANT DERIVED FROM GEOBACILLUS THERMODENITRIFICANS, AND PRODUCTION METHOD OF L-RIBOSE USING SAME

Номер: KR2012008748A2
Принадлежит:

The present invention relates to a novel mannose 6-phosphate isomerase mutant enzyme, and a method for preparing L-ribose using the enzyme, and more specifically, to a mannose 6-phosphate isomerase mutant enzyme and a recombinant expression vector containing the corresponding gene, a microorganism transformed with the same, a method for the mass production of a mannose 6-phosphate isomerase mutant using the same, and a method for producing L-ribose at a high yield by using the mannose 6-phosphate isomerase mutant.

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14-01-2019 дата публикации

음료용기 포장랩 절취선 형성장치

Номер: KR0101938367B1
Автор: 오덕근
Принадлежит: (주)서울에프엔비

... 본 발명은 음료용기 포장랩 절취선 형성장치에 관한 것으로서, 수평하게 이동되며, 포장랩이 씌워진 음료용기(A)의 바닥을 접촉지지하며 음료용기를 이송하는 하부컨베이어(110)와; 상기 하부컨베이어(110)의 일측에 수직하게 배치되어 상기 음료용기(A)의 측면을 접촉하며 음료용기를 이송하는 측면컨베이어(130)와; 상기 측면컨베이어(130)와 마주보는 방향에 음료용기(A)에 절취선(C)이 형성되기를 희망하는 높이에 위치되며, 상기 하부컨베이어(110)에 의해 이송되는 상기 음료용기(A)의 포장랩(B)에 절취선(C)을 형성하는 커팅나이프(140)를 포함하며, 상기 측면컨베이어(130)의 이송속도는 상기 하부컨베이어(110)의 이동속도 보다 빠르게 구비되는 것을 특징으로 한다.

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08-11-2016 дата публикации

7,8-DIOL SYNTHASE DERIVED FROM COLLETOTRICHUM GLOEOSPORIOIDES AND METHOD FOR PRODUCING 7,8-DIHYDROXY FATTY ACID

Номер: KR1020160128715A
Автор: OH, DEOK KUN, SEO, MIN JU
Принадлежит:

The present invention relates to a composition for producing 7,8-dihydroxy fatty acid comprising a 7,8-diol synthase as an active ingredient, and to a method for synthesizing 7,8-dihydroxy fatty acid by making the enzyme react with unsaturated fatty acid. According to the present invention, 7,8-dihydroxy linoleic acid, 7,8-dihydroxy oleic acid, and 7,8-dihydroxy alpha-linoleic acid can be produced at a high yield by using an environmentally-friendly biotransformation method having high specificity; and the produced 7,8-dihydroxy linoleic acid, 7,8-dihydroxy oleic acid, and 7,8-dihydroxy alpha-linoleic acid can be used as raw materials in various industrial fields, such as an emulsifying agent, an antimicrobial agent, nylon, etc. COPYRIGHT KIPO 2016 ...

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28-08-2015 дата публикации

METHOD FOR PRODUCING 13-HYDROXY-FATTY ACID USING LACTOBACILLUS ACIDOPHILUS DERIVED 13-LINOLEATE HYDRATASE, METHOD FOR PRODUCING Δ-DECALACTONE USING WALTOMYCES LIPOFER, AND COMPOSITION PRODUCED THEREBY

Номер: KR1020150098497A
Принадлежит:

The present invention relates to a method for producing 13-hydroxy-fatty acid using lactobacillus acidophilus derived 13-linoleate hydratase, a method for producing δ-decalactone using waltomyces lipofer, and a composition produced thereby. According to the present invention, 13-hydroxiy-9-octadecenoic acid, 13-hydroxy-9,15-octadecadienoic acid, and 13-hydroxy-6,9-octadecadienoic acid, which are raw materials for industrial goods, can be produced at high yield by a method with high specificity and eco-friendliness. The 13-hydroxide-9-octadecenoic acid produced thereby can be usefully used as a starting material for synthesis of lactone, and a lactone production method using yeasts is more eco-friendly and exhibits higher specificity compared to a conventional chemical production method. A method for producing δ-lactone through a cell originated enzyme reaction can mass-produce δ-decalactone, which is a raw material injected into food and exhibits a flavor of coconut or milk products, at ...

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15-11-2017 дата публикации

최적화된 리보스 5-인산 이성화효소를 코딩하는 유전자 및 이를 포함하는 미생물 및 이를 이용한 알로스 제조 방법

Номер: KR0101785299B1
Автор: 오덕근, 김경록, 박철순
Принадлежит: 대상 주식회사

... 본 발명은 최적화된 리보스 5-인산 이성화효소를 코딩하는 유전자 및 이를 포함하는 미생물 및 이를 이용한 알로스 제조 방법에 관한 것으로, 본 발명에 따르면, 알로스에 대해 기존 폴리뉴클레오티드 서열의 발현에 비해 우수한 발현과 알로스 전환활성을 보유하여 상대적으로 높은 수율로 알로스의 대량 생산이 가능하다.

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26-04-2018 дата публикации

HIGH-YIELD PRODUCTION METHOD OF GINSENOSIDE COMPOUND K BY ADDING HIGH-ACTIVITY α-L-ARABINOFURANOSIDASE ENZYME TO β-GLYCOSIDASE

Номер: KR1020180042695A
Принадлежит:

The present invention relates to a high-yield production method of ginsenoside compound K using β-glycosidase derived from Sulfolobus solfataricus and α-L-arabinofuranosidase derived from Dictyoglomus turgidum. By using an enzyme mixture of the present invention, the major ginsenosides present in ginseng extracts can be converted into ginsenoside compound K (C-K). In particular, the thermostable β-glycosidase enzyme of the present invention makes it possible to conduct reactions at a high temperature of 70°C or more and subsequently exclude various pollution sources from a reaction medium; and at the same time, does not generate other by-products in conversion of the major ginsenosides Rb1, Rb2, Rc, and Rd into C-K, and thus can enable a rapid and specific C-K conversion reaction to increase the production yield and produce C-K in high yield. Accordingly, the C-K production method using β-glycosidase and α-L-arabinofuranosidase of the present invention may be industrially advantageously ...

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28-02-2013 дата публикации

D-PSICOSE 3-EPIMERASE MUTANT WITH IMPROVED THERMAL STABILITY, AND CONTINUOUS PRODUCTION OF D-PSICOSE USING SAME

Номер: WO2013027999A3
Принадлежит:

The present invention relates to a D-psicose 3-epimerase mutant of which the thermal stability is improved by substituting an amino acid of a specific sequence number. In addition, the present invention relates to a recombinant vector comprising the gene of the D-psicose 3-epimerase mutant, and a recombinant strain transformed with the recombinant vector. Further, the present invention relates to an immobilized reactor prepared using the enzyme mutant or the recombinant vector, and a method for producing D-psicose using the immobilized reactor.

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20-12-2016 дата публикации

8,11-DIHYDROXY SYNTHASE AND METHOD FOR PRODUCING 8,11-DIHYDROXY FATTY ACID

Номер: KR1020160145395A
Принадлежит:

The present invention relates to a composition for producing 8,11-dihydroxy fatty acid comprising 8,11-dihydrogen synthase as an active ingredient and to a method for synthesizing 8,11-dihydroxy fatty acid by reacting the enzyme with an unsaturated fatty acid. According to the present invention, 8,11-dihydroxy linoleic acid and 8,11-dihydrogenated alpha-linolenic lycic acid can be produced by an enzyme conversion method which has a high specificity and is eco-friendly method, the produced 8,11-dihydroxy linoleic acid and 8,11-dihydrogenated alpha-linolenic lycic acid can be used as raw materials in various industrial fields such as emulsifiers, antibacterial agents, and nylon. COPYRIGHT KIPO 2016 ...

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28-02-2013 дата публикации

D-PSICOSE 3-EPIMERASE MUTANT WITH IMPROVED THERMAL STABILITY, AND CONTINUOUS PRODUCTION OF D-PSICOSE USING SAME

Номер: WO2013027999A9
Принадлежит:

The present invention relates to a D-psicose 3-epimerase mutant of which the thermal stability is improved by substituting an amino acid of a specific sequence number. In addition, the present invention relates to a recombinant vector comprising the gene of the D-psicose 3-epimerase mutant, and a recombinant strain transformed with the recombinant vector. Further, the present invention relates to an immobilized reactor prepared using the enzyme mutant or the recombinant vector, and a method for producing D-psicose using the immobilized reactor.

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26-04-2018 дата публикации

METHOD FOR PRODUCING GINSENOSIDE COMPOUND K BY USING NOVEL THERMO-STABLE β-GLUCOSIDASE

Номер: KR1020180042697A
Принадлежит:

The present invention relates to a method for producing ginsenoside compound K at a high yield by using a thermo-stable β-glycosidase enzyme derived from a Caldicellulosiruptor bescii strain. When the β-glycosidase enzyme of the present invention is used, the main ginsenoside in a ginseng extract can be converted to ginsenoside compound K (C-K). In particular, when the thermo-stable β-glycosidase enzyme of the present invention is used, the reaction can be performed at high temperatures of 70°C or higher. Accordingly, various contaminants can be removed from a reaction culture medium. At the same time, when the main ginsenosides Rb1, Rb2, Rc, Rd are converted to C-K, other byproducts are not produced. Consequently, specific C-K conversion reaction is possible and C-K can be produced at a high yield by increasing the production yield. Therefore, the C-K production method using the thermo-stable β-glycosidase enzyme derived from Caldicellulosiruptor bescii of the present invention can be ...

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26-07-2016 дата публикации

버콜데리아 타일란덴시스 유래 지방산화효소에 의한 13-수산화 리놀레익산의 고수율 제조방법 및 그 조성물

Номер: KR0101642583B1
Автор: 오덕근, 김백중, 안정웅
Принадлежит: 건국대학교 산학협력단

... 본 발명은 13-수산화 리놀레익산(13-Hydroxylioleic acid)의 생산방법 및 그 조성물에 관한 것으로 더욱 상세하게는버콜데리아 타일란덴시스(Burkholderia thailandensis) 균 유래의 수산화 합성효소(Lipoxygenase)를 이용하여 리놀레익산(linoleic acid) 반응조건을 최적화하고 최적화된 조건에서 반응시켜 13-수산화 리놀레익산을 고 수율로 생산하는 방법이다. 본 발명에 따르면, 높은 특이성과 친환경적인 방법으로 13-수산화 리놀레익산을 높은 수율로 생산할 수 있으며, 이렇게 생산된 13-수산화 리놀레익산은 다양한 산업분야의 원료물질로 사용될 수 있다.

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07-08-2018 дата публикации

옥수수수염물추출물 및 우유 함유 캡슐의 제조방법 및 이에 의해 제조된 캡슐

Номер: KR0101885523B1

... 본 발명은 옥수수수염물추출물 분말과 알긴산염을 우유에 넣고 혼합하여 혼합액을 제조하는 단계 (a); 및, 상기 혼합액을 다가 양이온을 포함하는 용액에 떨어뜨리는 단계 (b);를 포함하는 옥수수수염물추출물 및 우유 함유 캡슐의 제조방법에 관한 것으로, 본 발명의 캡슐에 탑재된 옥수수수염물추출물을 통해 우유에 함유된 지방성분의 흡수에 따른 지방 축적을 방지할 수 있는데, 우유에 함유되어 있는 지방을 인위적으로 제거하지 않아도 저지방 우유를 마시는 것과 유사한 효과를 기대할 수 있는 것이다. 또한, 본 발명은 캡슐 형태의 새로운 우유 음료를 개발하여 제공함으로써, 우유의 소비증대에도 이바지할 수 있다.

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05-02-2015 дата публикации

ALDOLASE, ALDOLASE MUTANT, AND METHOD AND COMPOSITION FOR PRODUCING TAGATOSE BY USING SAME

Номер: WO2015016544A1
Принадлежит:

The present invention relates to aldolase, an aldolase mutant, and a method and a composition for producing tagatose by using the same. The feature of the present invention is environment-friendly due to the use of an enzyme acquired from microorganisms, requires only a simple process of enzyme-immobilization, uses a low-cost substrate in a substrate compared with a conventional method for producing tagatose and has a remarkably high yield, thereby greatly reducing production costs and maximizing production effects.

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02-02-2016 дата публикации

ALDOLASE MUTANT AND TAGATOSE PRODUCTION METHOD USING SAME

Номер: KR1020160012001A
Принадлежит:

The present invention relates to an aldolase mutant and a tagatose production method using the same. More specifically, the present invention provides a composition for producing tagatose, which comprises a mutant of a fructose 1,6-bisphosphate aldolase enzyme as an active ingredient. The technology of the present invention is eco-friendly, since enzymes obtained from microorganisms are used, and the technology requires only an enzyme immobilization step. In addition, used is a substrate which requires reduced costs, in comparison with an existing method involved in the production of tagatose, while securing a remarkably high yield. Thus, production costs decrease while production effects are maximized. COPYRIGHT KIPO 2016 ...

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19-01-2012 дата публикации

MANNOSE 6-PHOSPHATE ISOMERASE MUTANT DERIVED FROM GEOBACILLUS THERMODENITRIFICANS, AND PRODUCTION METHOD OF L-RIBOSE USING SAME

Номер: KR2012008748A9
Принадлежит:

The present invention relates to a novel mannose 6-phosphate isomerase mutant enzyme, and a method for preparing L-ribose using the enzyme, and more specifically, to a mannose 6-phosphate isomerase mutant enzyme and a recombinant expression vector containing the corresponding gene, a microorganism transformed with the same, a method for the mass production of a mannose 6-phosphate isomerase mutant using the same, and a method for producing L-ribose at a high yield by using the mannose 6-phosphate isomerase mutant.

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10-05-2018 дата публикации

올레산 수화효소 2 및 이의 용도

Номер: KR0101856308B1

... 본 발명은 스테노트로포모나스 말토필리아 유래 올레산 수화효소 2 및 이를 발현하는 재조합 대장균을 이용하여 불포화지방산으로부터 하이드록시지방산들을 고수율로 생산하는 방법에 관한 것으로, 상기 방법을 통해 종래의 올레산 수화효소와 비교하여 하이드록시지방산들을 높은 속도와 수율로 생산할 수 있으며, 상기 생산된 하이드록시지방산들은 다양한 향료 생산에 이용될 수 있고, 고분자의 합성 및 유화제 생산에도 유용하게 사용될 수 있다.

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13-12-2017 дата публикации

INK PASTE FOR COLORING CONTACT LENS AND MANUFACTURING METHOD THEREOF

Номер: KR101808067B1
Принадлежит: INTEROJO INC.

The present invention relates to an ink paste for coloring a contact lens and a manufacturing method thereof. The manufacturing method comprises: a first step of manufacturing an ink paste by using 25-35 wt% of 2-Hydroxyethyl Methacrylate, 5-12 wt% of 2-ethoxyphenol, 10-25 wt% of Ethyl L-lactate, 0.5-3 wt% of Dodecanthiol, Dodecyl mercaptane, 0.5-3 wt% of Lauryl methacrylate, 0.5-2 wt% of Methacrylic acid, 0.5-3 wt% of azobis, and 30-45 wt% of cyclopentanone; a second step of stirring the ink paste through an ink paste stirrer; and a third step of inserting the completely mixed ink paste into a 3-roll mill and dispersing the paste to manufacture an ink paste for coloring a contact lens. As such, the ink paste is not harmful to a human body, and various colors, which users want, can be uniformly formed to color a contact lens. COPYRIGHT KIPO 2018 (AA) Ink paste for coloring a contact lens (S10) Manufacture the ink paste (S20) Stir (S30) Disperse ...

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28-04-2011 дата публикации

MANNOSE 6-PHOSPHATE ISOMERASE, MUTANTS THEREOF, AND USE THEREOF

Номер: WO2011049409A9
Принадлежит:

The present invention relates to a novel mannose 6-phosphate isomerase enzyme, mutants thereof, and a method of manufacturing L-ribose with such mutant enzymes. More particularly, the invention relates to mannose 6-phosphate isomerase enzymes and variants thereof, recombinant expression vectors containing expression genes thereof, microorganisms transformed to express such genes, manufacturing methods for producing large quantities of mannose 6-phosphate isomerase enzyme and its mutants, and production methods for high yields of L-ribose made with the mannose 6-phosphate isomerase mutant enzymes.

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