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Применить Всего найдено 54. Отображено 54.
12-08-2015 дата публикации

Method for Preparing Induced Pluripotency Stem Cell from Mesenchymal Stem Cell and Production thereof

Номер: KR0101544195B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태(Eckloniacava) 추출물을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용한 유도만능 줄기세포 제조 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 안전하고도 용이하게 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 다양한 세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 1
22-12-2017 дата публикации

보습력 및 지속력이 우수한 화장료 조성물 및 이의 제조방법

Номер: KR0101811849B1
Автор: 이계호, 오민선, 이상연, 김성준, 박지현
Принадлежит: 주식회사 에스티씨나라

... 본발명은 a) 휘발성 오일 및 디메티콘/비닐디메티콘크로스폴리머, 디메티콘크로스폴리머, 천연송진 및 카프릴릭/카프릭트리글리세라이드를 함유하는 유상 성분; b) 계면활성제; c) 유기계헥토라이트 및 분체를 함유하는 파우더 성분; 및 d) 정제수 및 암모늄폴리아크릴로일디메틸타우레이트/브이피코폴리머를 함유하는 수상 성분을 포함하는 화장료 조성물에 관한 것이다. 본 발명에 따른 화장료 조성물은 끈적임이 적고 피부 도포시 가벼운 사용감을 부여할 수 있다. 또한, 소량의 수분을 가진 역미셀에 의해 신규한 제형을 가짐에 따라 많은 양의 파우더를 배합할 수 있어 커버력이 우수하며 균일한 도포가 가능하며 일정한 점성을 가지며 수분 보호막으로 인해 보습감을 부여하는 장점이 있다.

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Номер записи: 2
03-11-2016 дата публикации

지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포주의 제조방법 및 수득된 세포주

Номер: KR0101671880B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 중간엽 줄기세포로부터 유도한 만능 줄기세포주(pluripotent stem cell line)를 제조하는 방법 및 이에 의해 수득된 유도만능 줄기세포주(기탁번호:KCLRF-BP-00319)에 관한 것이다. 구체적으로, 본 발명의 유도만능 줄기세포주의 제조방법은 (a) 인간의 지방으로부터 중간엽 줄기세포(mesenchymal stem cell)를 수득하는 단계; (b) 상기 중간엽 줄기세포를 감태 추출물(Eckloniacava)을 포함하는 역분화용 배지로 콜로니를 형성시키는 단계; 및 (c) 상기 콜로니를 계대배양하여 유도만능 줄기세포주를 수득하는 단계;를 포함한다. 본 발명에 따른 유도만능 줄기세포주는 본 발명자들에 의해 최초로 구축된 것이며, 본 발명의 만능 줄기세포주는 다양한 세포로 분화될 수 있으며, 세포이식 치료를 통하여 다양한 질병 또는 질환을 치료할 수 있다.

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Номер записи: 3
23-06-2016 дата публикации

Method for Preparing Induced Pluripotency Stem Cell from Mesenchymal Stem Cell and Production thereof

Номер: KR0101633019B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 중간엽 줄기세포로부터 유도한 만능 줄기세포주(pluripotent stem cell line)를 제조하는 방법 및 이에 의해 수득된 유도만능 줄기세포주(기탁번호:KCLRF-BP-00318)에 관한 것이다. 구체적으로, 본 발명의 유도만능 줄기세포주의 제조방법은 (a) 인간의 탯줄로부터 중간엽 줄기세포(mesenchymal stem cell)를 수득하는 단계; (b) 상기 중간엽 줄기세포를 감태 추출물(Ecklonia cava)을 포함하는 역분화용 배지로 콜로니를 형성시키는 단계; 및 (c) 상기 콜로니를 계대배양하여 유도만능 줄기세포주를 수득하는 단계;를 포함한다. 본 발명에 따른 유도만능 줄기세포주는 본 발명자들에 의해 최초로 구축된 것이며, 본 발명의 만능 줄기세포주는 다양한 세포로 분화될 수 있으며, 세포이식 치료를 통하여 다양한 질병 또는 질환을 치료할 수 있다.

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Номер записи: 4
25-01-2017 дата публикации

플로로탄닌 분획물을 이용한 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하는 방법

Номер: KR0101699761B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태, 가시뼈대그물말, 참가죽그물바탕말, 괭생이모자반 및 패 등으로 이루어진 군에서 선택된 1종의 갈조류에서 추출 및 분리된 플로로탄닌(phlorotannin) 분획물을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용한 유도만능 줄기세포 제조 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 안전하고도 용이하게 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 다양한 세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 5
10-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO ADIPOCYTE

Номер: KR1020160066328A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into adipocyte. By means of the culture medium composition, according to the present invention, induced pluripotent stem cells can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into adipocyte. Therefore, the present invention can be utilized for a patient-specific cell therapy product. COPYRIGHT KIPO 2016 (AA) Cell inoculation (BB) Fat derived mesenchymal stem cells (CC) Induced pluripotent stem cells (DD) Fat cell ...

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Номер записи: 6
10-08-2015 дата публикации

Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Adipocyte

Номер: KR0101542850B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Eckloniacava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 지방세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 지방세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 7
03-11-2016 дата публикации

지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하여 신경세포로 분화 시키는 방법

Номер: KR0101671882B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Eckloniacava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 신경세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 신경세포로의 분화가 가능하므로 환자맞춤형 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 8
03-11-2016 дата публикации

지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하여 간세포로 분화 시키는 방법

Номер: KR0101671883B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Eckloniacava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 지방세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 지방세포로의 분화가 가능하므로 환자 맞춤형 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 9
03-02-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELL LINE FROM MESENCHYMAL STEM CELL, AND CELL LINE OBTAINED THEREBY

Номер: KR1020160012686A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a method for preparing an induced pluripotent stem cell line from a mesenchymal stem cell, and the induced pluripotent stem cell line (accession number: KCLRF-BP-00318) obtained thereby. Specifically, the method for preparing an induced pluripotent stem cell line according to the present invention comprises the following steps: (a) obtaining a mesenchymal stem cell from a human umbilical cord; (b) forming a colony by culturing the mesenchymal stem cell in a dedifferentiation medium including an Ecklonia cava extract: and (c) obtaining an induced pluripotent stem cell line by subculturing the colony. The induced pluripotent stem cell line according to the present invention is established first by the present inventors, and the pluripotent stem cell line according to the present invention can be differentiated into various cells and used for treating various diseases or disorders through cell transportation therapy. COPYRIGHT KIPO 2016 ...

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Номер записи: 10
23-12-2015 дата публикации

METHOD FOR PRODUCING PLURIPOTENT STEM CELLS FROM ADIPOSE TISSUE-DERIVED MESENCHYMAL STEM CELLS, AND PLURIPOTENT STEM CELLS PRODUCED BY SAME METHOD

Номер: KR1020150143203A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a culture medium composition for backward differentiation of pluripotent stem cells, containing an Ecklonia cava extract. In addition, the present invention relates to a method for producing pluripotent stem cells using the culture medium composition. If using the culture medium composition according to the present invention, it is possible to efficiently produce pluripotent stem cells easily and safely by using adipose tissue-derived mesenchymal stem cells, and the produced pluripotent stem cells can differentiate into various cells, thereby being useful as a cell therapy product. COPYRIGHT KIPO 2016 ...

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Номер записи: 11
26-11-2015 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENCY STEM CELLS FROM MESENCHYMAL STEM CELLS BY USING PHLOROTANNIN FRACTION

Номер: WO2015178728A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition for the dedifferentiation of induced pluripotency stem cells, containing a phlorotannin fraction extracted and isolated from one type of brown algae selected from the group consisting of Ecklonia cava, Dictyopteris prolifera, Dictyota coriacea, Sargassum horneri, Ishige okamurai and the like. In addition, the present invention relates to a method for preparing induced pluripotency stem cells by using the medium composition. Induced pluripotency stem cells can be safely, easily and effectively prepared by using mesenchymal stem cells by using the medium composition of the present invention, and the prepared induced pluripotency stem cells can be differentiated into various cells, and thus can be useful as a cell therapeutic agent.

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Номер записи: 12
09-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO HEPATOCYTES

Номер: WO2016088933A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into hepatocytes. By means of the culture medium composition, according to the present invention, induced pluripotent stems cell can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into hepatocytes. Therefore, the present invention can be utilized for a patient-specific cell therapy product.

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Номер записи: 13
09-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO CHONDROCYTES

Номер: WO2016088929A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into chondrocytes. By means of the culture medium composition, according to the present invention, induced pluripotent stems cell can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into chondrocytes. Therefore, the present invention can be utilized for a patient-specific cell therapy product.

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Номер записи: 14
03-04-2017 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELLS INDUCED FROM MESENCHYMAL STEM CELLS INTO PANCREATIC BETA CELLS

Номер: KR1020170036371A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared using a medium composition for dedifferentiation of induced pluripotency stem cells, comprising Ecklonia cava into pancreatic beta cells. According to the present invention, the induced pluripotent stem cells can be efficiently prepared using mesenchymal stem cells, and the prepared pluripotent stem cells can differentiate into the pancreatic beta cells, thereby being usefully used as a cell therapy agent. COPYRIGHT KIPO 2017 ...

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Номер записи: 15
11-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENCY STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO ADIPOCYTE

Номер: KR1020150050865A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a medium composition for dedifferentiating an induced pluripotency stem cell including an Eckloniacava extract. Also, the present invention relates to a method for differentiating an induced pluripotency stem cell manufactured by using the medium composition into an adipocyte. The medium composition according to the present invention is used to efficiently manufacture an induced pluripotency stem cell by using a mesenchymal stem cell, and the manufactured pluripotency stem cell can be differentiated into adipocyte, thereby being useful as a cell treating agent. COPYRIGHT KIPO 2015 ...

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Номер записи: 16
09-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELL LINE FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS, AND OBTAINED CELL LINE

Номер: WO2016088928A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a method for preparing a pluripotent stem cell line induced from mesenchymal stem cells and the induced pluripotent stem cell line (accession number: KCLRF-BP-00319) obtained by means of same. More particularly, a method for preparing an induced pluripotent stem cell line, according to the present invention, comprises the steps of: (a) obtaining mesenchymal stem cells from human adipose tissues; (b) forming the mesenchymal stem cells into a colony by means of a dedifferentiation culture medium comprising an Ecklonia cava extract; and (c) obtaining an induced pluripotent stem cell line by subculturing the colony. An induced pluripotent stem cell line, according to the present invention, has been prepared by the inventors of the present invention for the first time. A pluripotent stem cell line, according to the present invention, can be differentiated into various cells and enables treatments of various diseases and illnesses by means of a cell transplantation ...

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Номер записи: 17
09-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO NERVE CELLS

Номер: WO2016088930A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into nerve cells. By means of the culture medium composition, according to the present invention, induced pluripotent stems cell can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into nerve cells. Therefore, the present invention can be utilized for a patient-specific cell therapy product.

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Номер записи: 18
09-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO ADIPOCYTES

Номер: WO2016088932A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into adipocytes. By means of the culture medium composition, according to the present invention, induced pluripotent stem cells can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into adipocytes. Therefore, the present invention can be utilized for a patient-specific cell therapy product.

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Номер записи: 19
10-06-2016 дата публикации

METHOD FOR PRODUCING INDUCED PLURIPOTENCY STEM CELL LINE FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELL AND CELL LINE OBTAINED THROUGH SAME

Номер: KR1020160066324A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a method for producing a pluripotency stem cell line induced from a mesenchymal stem cell and to an induced pluripotency stem cell line (donation number: KCLRF-BP-00319) obtained through the same. In particular, a method for producing an induced pluripotency stem cell line according to the present invention comprises the steps of: (a) obtaining a mesenchymal stem cell from human fat; (b) producing a colony from the mesenchymal stem cell in a reverse differentiation culture medium including an Ecklonia cava extract; and (c) obtaining an induced pluripotency stem cell line by successively culturing the colony. The induced pluripotency stem cell line according to the present invention has been constructed by the applicants of the present invention for the first time, may be differentiated into various cells, and may treat various diseases through a cell transplantation treatment. COPYRIGHT KIPO 2016 ...

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Номер записи: 20
11-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENCY STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO CHONDROCYTE

Номер: KR1020150050862A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a medium composition for backward differentiating induced pluripotency stem cell including an extract of Ecklonia cava, and to a method for differentiating induced pluripotency stem cell manufactured by using the medium composition into chondrocyte. According to the present invention, the medium composition can effectively manufacture induced pluripotency stem cell by using mesenchymal stem cell, and the manufactured pluripotency stem cell can be differentiated into chondrocyte, thereby being used as a cell medicine. COPYRIGHT KIPO 2015 ...

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Номер записи: 21
10-08-2015 дата публикации

Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Neuron

Номер: KR0101542847B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Ecklonia cava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 신경세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 신경세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 22
11-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO OSTEOBLAST

Номер: KR1020150050863A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell produced by using the medium composition into an osteoblast. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into osteoblasts. COPYRIGHT KIPO 2015 ...

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Номер записи: 23
10-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO OSTEOBLAST

Номер: KR1020160066327A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into osteoblast. By means of the culture medium composition, according to the present invention, induced pluripotent stem cells can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into osteoblast. Therefore, the present invention can be utilized for a patient-specific cell therapy product. COPYRIGHT KIPO 2016 (AA) Fat-derived mesenchymal stem cells (BB) Cell inoculation (CC) Induced pluripotent stem cells (DD) Osteoblast ...

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Номер записи: 24
03-11-2016 дата публикации

지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하여 연골세포로 분화 시키는 방법

Номер: KR0101671879B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Eckloniacava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 연골세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 연골세포로의 분화가 가능하므로 환자 맞춤형 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 25
30-03-2017 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENCY STEM CELLS INDUCED FROM MESENCHYMAL STEM CELLS INTO PANCREATIC BETA CELLS

Номер: WO2017051970A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a method for differentiating induced pluripotency stem cells prepared using a medium composition for dedifferentiation of induced pluripotency stem cells comprising Ecklonia cava into pancreatic beta cell. According to the present invention, induced pluripotent stem cells can be efficiently prepared using mesenchymal stem cells, and the prepared pluripotent stem cells can differentiate into pancreatic beta cells and thus can be effectively used as a cell therapy agent.

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Номер записи: 26
07-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO OSTEOBLAST

Номер: WO2015064803A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell produced by using the medium composition into an osteoblast. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into osteoblasts.

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Номер записи: 27
11-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENCY STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO HEPATOCYTE

Номер: KR1020150050864A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a medium composition for dedifferentiating an induced pluripotency stem cell including an Eckloniacava extract. Also, the present invention relates to a method for differentiating an induced pluripotency stem cell manufactured by using the medium composition into hepatocyte. The medium composition according to the present invention is used to efficiently manufacture an induced pluripotency stem cell by using a mesenchymal stem cell, and the manufactured pluripotency stem cell can be differentiated into hepatocyte, thereby being useful as a cell treating agent. COPYRIGHT KIPO 2015 ...

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Номер записи: 28
11-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO CHONDROCYTE

Номер: KR1020150050861A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell manufactured by using the medium composition into a chondrocyte. According to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be manufactured efficiently, and the pluripotent stem cells which have been manufactured can be useful as a cell treatment agent by being capable of being differentiated into chondrocytes when using the medium composition. COPYRIGHT KIPO 2015 ...

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Номер записи: 29
07-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO ADIPOCYTE

Номер: WO2015064800A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell produced by using the medium composition into an adipocyte. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into adipocytes.

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Номер записи: 30
09-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO OSTEOBLASTS

Номер: WO2016088931A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into osteoblasts. By means of the culture medium composition, according to the present invention, induced pluripotent stems cell can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into osteoblasts. Therefore, the present invention can be utilized for a patient-specific cell therapy product.

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Номер записи: 31
10-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO NERVE CELL

Номер: KR1020160066326A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into nerve cell. By means of the culture medium composition, according to the present invention, induced pluripotent stem cells can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into nerve cell. Therefore, the present invention can be utilized for a patient-specific cell therapy product. COPYRIGHT KIPO 2016 (AA) Cell inoculation (BB) Fat-derived mesenchymal stem cells (CC) Induced pluripotent stem cells (DD) Neuron ...

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Номер записи: 32
07-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO NEURON

Номер: WO2015064804A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell produced by using the medium composition into a neuron. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into neurons.

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Номер записи: 33
07-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO HEPATOCYTE

Номер: WO2015064802A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell produced by using the medium composition into a hepatocyte. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into hepatocytes.

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Номер записи: 34
03-02-2016 дата публикации

COSMETIC COMPOSITION WITH EXCELLENT MOISTURIZING ABILITY AND PERSISTENCY AND PRODUCTION METHOD THEREOF

Номер: KR1020160012963A
Автор: LEE, KYE HO, OH, MIN SUN, LEE, SANG YEON, KIM, SUNG JUN, PARK, JI HYUN
Принадлежит:

The present invention relates to a cosmetic composition which comprises: (a) an oil-based component containing volatile oil and a dimethicone/vinyl dimethicone crosspolymer, a dimethicone crosspolymer, a natural pine resin, and caprylic/capric tryglycerides; (b) a surfactant; (c) a powdered component containing organic hectorite and and powder; and (d) water-based component containing purified water and an ammonium polyacryloyldimethyl taurate/VP copolymer. According to the present invention, the cosmetic composition is less sticky can create light feeling when applying the composition onto skin. In addition, mixing a large quantity of powder is possible as the composition can have a novel formulation by reversed micelles with reduced moisture. Thus, uniform application is possible while exhibiting excellent covering ability. The composition also has uniform viscosity and can offer a user with moisturization effects owing to moisture protection film. COPYRIGHT KIPO 2016 ...

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Номер записи: 35
07-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO CHONDROCYTE

Номер: WO2015064805A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell produced by using the medium composition into a chondrocyte. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into chondrocytes.

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Номер записи: 36
05-02-2016 дата публикации

Method for Preparing patient-specific Induced Pluripotency Stem Cell from adipose-derived Mesenchymal Stem Cell and Production thereof

Номер: KR0101592401B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태(Eckloniacava) 추출물을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용한 유도만능 줄기세포 제조 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 지방-유래 중간엽 줄기세포를 이용하여 안전하고도 용이하게 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 다양한 세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 37
10-08-2015 дата публикации

Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Hepatocyte

Номер: KR0101542849B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Eckloniacava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 간세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 간세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 38
02-12-2015 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENCY STEM CELLS FROM MESENCHYMAL STEM CELLS BY USING PHLOROTANNIN FRACTION

Номер: KR1020150135136A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a medium composition for the dedifferentiation of induced pluripotency stem cells, containing a phlorotannin fraction extracted and isolated from one type of brown algae selected from the group consisting of Ecklonia cava, Dictyopteris prolifera, Dictyota coriacea, Sargassum horneri, Ishige okamurai and the like. In addition, the present invention relates to a method for preparing induced pluripotency stem cells by using the medium composition. Induced pluripotency stem cells can be safely, easily and effectively prepared by using mesenchymal stem cells by using the medium composition of the present invention, and the prepared induced pluripotency stem cells can be differentiated into various cells, and thus can be useful as a cell therapeutic agent. COPYRIGHT KIPO 2016 ...

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Номер записи: 39
10-08-2015 дата публикации

Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Chondrocyte

Номер: KR0101542846B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Ecklonia cava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 연골세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 연골세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 40
11-05-2015 дата публикации

METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELL FROM MESENCHYMAL STEM CELL AND INDUCED PLURIPOTENT STEM CELL PRODUCED BY SAME

Номер: KR1020150050823A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for producing induced pluripotent stem cells using the medium composition. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced safely, easily, and efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into a variety of cells. COPYRIGHT KIPO 2015 ...

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Номер записи: 41
10-08-2015 дата публикации

Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Osteoblast

Номер: KR0101542848B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Ecklonia cava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 골아세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 골아세포로의 분화가 가능하므로 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 42
29-06-2015 дата публикации

FUNCTIONAL FERMENTED COMPOSITION FOR CONTROLLING WEIGHT AND MANUFACTURING METHOD THEREOF

Номер: KR1020150071942A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a functional fermented composition for reducing weight, which includes much alpha amylase, protease and lipase by mixing mate, chicory fiber Guarana, chia seed and papain with fermented products made by fermenting crops consisting of rice bran, black rice, brown rice, brown glutinous rice, Carex kobomugi Ohwi, glutinous rice barley, malt, wheat bran and small beam with vegetable powders with use of microorganisms. COPYRIGHT KIPO 2015 (AA) Washing (BB) Steam pressure (CC) Atmospheric pressure : 1.2 ~ 1.5kg/cm^2 (DD) Temperature : 100-130°C (EE) Time : 1-3 hours (FF) Natural cooling and Refregeration (GG) Natural cooling : 60 minutes (HH) Refregeration : 25-35°C, Air-cooling (II) Inoculation and Fermentation (JJ) Inoculation : Rhizopus, nigncans + Rhizopus,japonicus + Asperglllus wentii (KK) Fermentation temperature and humidity : 25-35°C, 45-60% (LL) Fermentation time : 16-20 hours (MM) Drying(Air Drying) (NN) Temperature : 45-55(Air Drying) (OO) Percentage ...

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Номер записи: 43
10-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO CARTILAGE CELL

Номер: KR1020160066325A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into cartilage cell. By means of the culture medium composition, according to the present invention, induced pluripotent stem cells can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into cartilage cell. Therefore, the present invention can be utilized for a patient-specific cell therapy product. COPYRIGHT KIPO 2016 (AA) Cell inoculation (BB) Fat-derived mesenchymal stem cells (CC) Induced pluripotent stem cells (DD) Chondrocyte ...

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Номер записи: 44
17-12-2015 дата публикации

METHOD FOR MANUFACTURING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND INDUCED PLURIPOTENT STEM CELLS MANUFACTURED BY SAME METHOD

Номер: WO2015190636A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition for reprogramming induced pluripotent stem cells, containing an Ecklonia cava extract. Also, the present invention relates to a method for manufacturing induced pluripotent stem cells by using the medium composition. When the medium composition according to the present invention is used, induced pluripotent stem cells can be efficiently produced using adipose-derived mesenchymal stem cells safely and easily. The manufactured pluripotent stem cells are differentiable into various cells, and thus can be favorably used as a cell therapeutic agent.

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Номер записи: 45
07-05-2015 дата публикации

METHOD FOR DIFFERENTIATING PLURIPOTENT STEM CELL INDUCED FROM MESENCHYMAL STEM CELL INTO CHONDROCYTE

Номер: WO2015064805A8
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for differentiating an induced plurlipotent stem cell produced by using the medium composition into a chondrocyte. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into chondrocytes.

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Номер записи: 46
03-11-2016 дата публикации

지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하여 지방세포로 분화시키는 방법

Номер: KR0101671884B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Eckloniacava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 지방세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 지방세포로의 분화가 가능하므로 환자 맞춤형 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 47
20-10-2015 дата публикации

functional fermentation food compositions for controlling of body weight and method of manufacturing the same

Номер: KR0101561931B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 미강, 흑미, 현미, 현미찹쌀, 통보리, 찹쌀보리, 맥아, 밀기울, 쥐눈이콩로 이루어진 곡류와 야채분말에 미생물을 발효시켜 제조된 발효물에, 올리고당, 마테, 치커리화이버, 과라나, 치아씨드 및 파파인을 혼합하여 알파-아밀라아제, 단백질분해효소, 지질분해효소가 다량 함유되어 체중 감량 효과를 갖는 발효식품 조성물에 관한 것이다.

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Номер записи: 48
13-02-2019 дата публикации

계좌 예금액을 분할하여 관리하는 은행 업무 관리 서버 및 계좌 예금액 분할 관리 방법

Номер: KR1020190015076A
Автор: 현재혁, 김기창, 김윤화, 이윤명, 이병수, 송형근, 오민선, 조수진
Принадлежит:

... 본 발명에 따른 계좌 예금액을 분할하여 관리하는 은행 업무 관리 서버는, 사용자 단말기에 설치되는 에이전트와 연동하여 사용자의 로그인 정보를 설정하는 접속 정보 관리부, 사용자의 계좌 개설 요청에 따라 에이전트와 연동하여 계좌 개설을 위해 필요한 정보를 입력 받고, 정보에 따라 계좌를 개설하는 계좌 정보 관리부 및 계좌 정보 관리부를 통해 개설된 계좌를 모(母)계좌로 하여 모계좌의 예금액 중 적어도 일부를 예금액으로 하는 자(子)계좌를 개설하여 모계좌의 예금액과 자계좌의 예금액을 분리하여 관리하며, 미리 설정된 방식에 기초하여 자계좌의 거래를 관리하는 예금액 분할 관리부를 포함한다.

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Номер записи: 49
28-01-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELL LINE FROM MESENCHYMAL STEM CELLS, AND CELL LINE OBTAINED THEREBY

Номер: WO2016013710A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to: a method for preparing an induced pluripotent stem cell line from mesenchymal stem cells; and an induced pluripotent stem cell line (deposit number: KCLRF-BP-00318) obtained thereby. Specifically, the method for preparing an induced pluripotent stem cell line, of the present invention, comprises the steps of: (a) obtaining mesenchymal stem cells from a human umbilical cord; (b) forming, from the mesenchymal stem cells, a colony with a medium for dedifferentiation containing an Ecklonia cava extract; and (c) obtaining an induced pluripotent stem cell line by subculturing the colony. The induced pluripotent stem cell line according to the present invention was first prepared by the present inventors, and the pluripotent stem cell line of the present invention can be differentiated into various cells and can treat various diseases or disorders through cell transplant therapy.

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Номер записи: 50
10-06-2016 дата публикации

METHOD FOR PREPARING INDUCED PLURIPOTENT STEM CELLS FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS AND DIFFERENTIATING SAME INTO HEPATOCYTE

Номер: KR1020160066329A
Автор: LEE, SANG YEON, JUNG, WON JU, KIM, HO BIN, OH, MIN SUN, LEE, KYE HO
Принадлежит:

The present invention relates to a culture medium composition, for induced pluripotent stem cell dedifferentiation, comprising an Ecklonia cava extract. In addition, the present invention relates to a method for differentiating induced pluripotent stem cells, which are prepared by means of the culture medium composition, into adipocyte. By means of the culture medium composition, according to the present invention, induced pluripotent stem cells can be efficiently prepared by using mesenchymal stem cells, and the prepared pluripotent stem cells can be differentiated into adipocyte. Therefore, the present invention can be utilized for a patient-specific cell therapy product. COPYRIGHT KIPO 2016 (AA) Cell inoculation (BB) Fat-derived mesenchymal stem cells (CC) Induced pluripotent stem cells (DD) Liver cells ...

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Номер записи: 51
03-11-2016 дата публикации

지방-유래 중간엽 줄기세포로부터 유도만능 줄기세포를 제조하여 골아세포로 분화 시키는 방법

Номер: KR0101671881B1
Автор: 이상연, 정원주, 김호빈, 오민선, 이계호
Принадлежит: 주식회사 비비에이치씨

... 본 발명은 감태 추출물(Eckloniacava)을 포함하는 유도만능 줄기세포(induced pluripotency stem cell) 역분화용 배지 조성물에 관한 것이다. 또한, 본 발명은 상기 배지 조성물을 이용하여 제조된 유도만능 줄기세포로부터 골아세포로 분화시키는 방법에 관한 것이다. 본 발명에 따른 배지 조성물을 이용하면 중간엽 줄기세포를 이용하여 유도만능 줄기세포를 효율적으로 제조할 수 있으며, 제조된 만능 줄기세포는 골아세포로의 분화가 가능하므로 환자 맞춤형 세포 치료제로서 유용하게 사용될 수 있다.

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Номер записи: 52
23-05-2018 дата публикации

COMBINED-TYPE MULTI-PURPOSE CLEANING TOOL WHICH USES OPTIONAL CLEANING MATERIALS AND SPRAYS CLEANING SOLUTION

Номер: KR1020180053532A
Автор: OH, MIN SUN
Принадлежит:

The present invention relates to a combined-type multi-purpose cleaning tool which uses optional cleaning materials and sprays a cleaning solution. The multi-purpose cleaning tool comprises a brush (1) with thick bristles for a cleaning part, a brush (2) with thin bristles for a cleaning part, a solution injecting device, and a solution spraying hole. Accordingly, the present invention can control the folding and unfolding of the brush through a click-type operation to form a single structure, and simultaneously, sprays the cleaning solution using a syringe type device. The multi-purpose cleaning tool is easy to carry and use. COPYRIGHT KIPO 2018 ...

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Номер записи: 53
07-05-2015 дата публикации

METHOD FOR PRODUCING INDUCED PLURIPOTENT STEM CELL FROM MESENCHYMAL STEM CELL AND INDUCED PLURIPOTENT STEM CELL PRODUCED BY THE METHOD

Номер: WO2015064795A1
Автор: LEE, Sang Yeon, JUNG, Won Ju, KIM, Ho, Bin, OH, Min Sun, LEE, Kye Ho
Принадлежит:

The present invention relates to a medium composition containing an Ecklonia cava extract for dediffentiating an induced pluripotent stem cell. Also, the present invention relates to a method for producing induced pluripotent stem cells using the medium composition. When using the medium composition, according to the present invention, induced pluripotent stem cells using mesenchymal stem cells can be produced safely, easily, and efficiently, and the pluripotent stem cells which have been produced can be useful as a cell treatment agent by being capable of being differentiated into a variety of cells.

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Номер записи: 54