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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 15. Отображено 15.
28-11-2013 дата публикации

MULTILAYER COATING FORM OF ORALLY ADMINISTERED PHARMACEUTICAL COMPOSITION CONTAINING OMEGA-3 FATTY ACID OR ALKYL ESTER THEREOF AND STATIN BASED DRUG

Номер: WO2013176455A1
Принадлежит:

The present invention provides a multilayer coating form (multilayer-coated form) of pharmaceutical composition comprising an omega-3 fatty acid or an alkyl ester thereof and a statin based drug. More specifically, the present invention provides an orally administered pharmaceutical composition comprising: (a) a gelatin capsule core containing an omega-3 fatty acid or an alkyl ester thereof; (b) a first coating layer formed by coating, onto the gelatin capsule core, hydroxypropyl methylcellulose and a copolymer comprising a 1:2:1 weight ratio of butyl methacrylate and (2-dimethylaminoethyl) methacrylate and methyl methacrylate; and (c) a second coating layer formed by coating, onto the first coating layer, a coating solution containing a statin based drug.

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26-12-2018 дата публикации

PHARMACEUTICALLY ACCEPTABLE SALTS OF ALKYLCARBAMOYL NAPHTHALENYLOXY OCTENOYL HYDROXYAMIDE OR DERIVATIVES THEREOF AND METHOD FOR MANUFACTURING SAME

Номер: KR1020180136741A
Принадлежит:

The present invention relates to pharmaceutically acceptable salts of alkyl carbamoyl naphthalenyloxy octenoyl hydroxyamide or derivatives thereof and a method for manufacturing the same. The stability against moisture can be enhanced while retaining properties such as efficacy and effective amount of pharmaceutically acceptable salts of alkyl carbamoyl naphthalenyloxy octenoyl hydroxyamide or derivatives thereof. Further, by enhancing hygroscopicity, the production and commercialization of the preparation can be simplified. COPYRIGHT KIPO 2019 (AA) Comparative example 1 (BB) Example 1 (CC) Example 2 ...

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07-05-2020 дата публикации

PHARMACEUTICAL COMPOSITION CONTAINING ALKYL CARBAMOYL NAPHTHALENYLOXY OCTENOYL HYDROXYAMIDE PHOSPHATE, TARTRATE OR COMBINATION THEREOF, AND PREPARATION METHOD THEREFOR

Номер: WO2020091326A1
Принадлежит:

The present invention relates to a pharmaceutical composition containing an alkyl carbamoyl naphthalenyloxy octenoyl hydroxyamide phosphate compound (hereinafter referred to as CG200745PPA) or a derivative thereof, and can provide a pharmaceutical composition in a tablet, granule, powder, capsule, dry syrup or injection form. By providing the composition in various forms, a suitable form can be selected and easily applied when oral administration is difficult.

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20-12-2018 дата публикации

PHARMACEUTICALLY ACCEPTABLE SALT OF ALKYLCARBAMOYL NAPHTHALENYLOXY OCTENOYLHYDROXYAMIDE OR OF DERIVATIVE THEREOF AND METHOD FOR PREPARING SAME

Номер: WO2018230829A1
Принадлежит:

The present invention relates to a pharmaceutically acceptable salt of alkylcarbamoyl naphthalenyloxy octenoylhydroxyamide or of a derivative thereof and a method for preparing same, and can improve moisture stability while maintaining the characteristics, such as the efficacy and effective dose, of a pharmaceutically acceptable salt of alkylcarbamoyl naphthalenyloxy octenoylhydroxyamide or of a derivative thereof. In addition, the present invention can simplify the production and manufacturing process of a formulation by improving hygroscopicity.

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08-07-2016 дата публикации

COMPOSITE TABLET FOR ORAL ADMINISTRATION CONTAINING MELATONIN AND SERTRALINE

Номер: KR1020160081646A
Принадлежит:

The present invention provides a composite tablet for oral administration and a method for manufacturing the same, the composite tablet for oral administration comprising: a sustained release layer including melatonin or pharmaceutically acceptable salts thereof, and a gel-forming polymer as a sustained release agent; and an immediate release layer including sertraline or pharmaceutically acceptable salts thereof. COPYRIGHT KIPO 2016 (A1,A2,A3,A4) Controlled release layer (B1,B2,B3,B4) Immediate release layer (CC) Melatonin (DD) Sertraline (EE) Gelation of the controlled release layer ...

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26-09-2019 дата публикации

TRANSDERMAL ABSORPTION PREPARATION

Номер: WO2019182343A1
Принадлежит:

The present invention relates to a transdermal absorption preparation containing polmacoxib, the preparation being capable of minimizing the influence of both extrinsic and intrinsic factors and maintaining stable blood concentrations for a predetermined period of time, while maintaining characteristics, such as efficacy and effective dose, of polmacoxib. In addition, side effects, caused by the administration of the preparation, on the internal organs can be minimized and administration frequency can be reduced, and thus patient compliance can be increased.

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02-10-2015 дата публикации

Aqueous pharmaceutical composition for parenteral administration

Номер: KR0101556535B1
Автор: 조재평, 오의철
Принадлежит: 건일제약 주식회사

... 본 발명은 치료학적으로 유효한 양의 항암제; 비이온성 계면활성제; 지방산 또는 그의 염; 및 물을 포함하는, 비경구 투여용 수성 약학 조성물을 제공한다. 본 발명의 약학 조성물은 물을 매질로서 포함하는 수성의 액상 제제로서, 우수한 안정성을 갖는다. 또한, 본 발명에 따른 약학 조성물은 점도가 낮은 액상제제이기 때문에, 하나의 단위 투여형태로 사용될 수 있다. 따라서, 본 발명의 액상 제제는 기존 제제 탁소테르와 같이 프리믹스(premix) 제조 과정 없이 생리염수 또는 포도당용액에 주입하여 환자에게 투여될 수 있다.

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21-03-2019 дата публикации

PHARMACEUTICAL COMPOSITION FOR TREATING ACUTE AND CHRONIC PAIN, CONTAINING POLMACOXIB AND TRAMADOL

Номер: WO2019054606A1
Принадлежит:

The present invention relates to a complex comprising polmacoxib and tramadol. The present invention relates to a pharmaceutical composition and a medicine or an analgesic, all of which contain two types of active ingredients of polmacoxib and tramadol, and, more specifically, to effects and uses of the active ingredients in a medicine or an analgesic for the treatment of moderate acute and chronic pain caused by inflammatory and multiple factors.

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07-07-2016 дата публикации

COMPOSITE TABLET FOR ORAL ADMINISTRATION COMPRISING MELATONIN AND SERTRALINE

Номер: WO2016108507A3
Принадлежит:

The present invention provides a composite tablet for oral administration and a method for manufacturing the same, the composite tablet for oral administration comprising: a sustained release layer including melatonin or a pharmaceutically acceptable salt thereof, and a gel-forming polymer as a sustained release agent; and an immediate release layer including sertraline or a pharmaceutically acceptable salt thereof.

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23-01-2020 дата публикации

ORALLY ADMINISTERED PHARMACEUTICAL COMPOSITION COMPRISING FAB I INHIBITORS AND METHOD FOR PREPARING SAME

Номер: WO2020017756A1
Принадлежит:

The present invention relates to an orally administered pharmaceutical composition comprising Fab I inhibitors, and to a method for preparing same. The present invention may be applied effectively to bacterial infections resistant to antibiotics and the like. More specifically, the present invention can more rapidly initiate therapeutic effects by improving dissolution and elution rates. Furthermore, the present invention can improve the mixing and content uniformity in preparations by regulating the particle size.

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17-02-2016 дата публикации

Entecavir-containing microspheres and process for preparing the same

Номер: KR0101594820B1
Автор: 조재평, 이풍석, 박소라
Принадлежит: 건일제약 주식회사

... 본 발명은 계면활성제 또는 양친성 수용성 고분자로 구성된 미립구 내부에 엔테카비르가 봉입된, 엔테카비르-함유 미립구 및 이의 제조방법을 제공한다. 또한, 본 발명은 상기 엔테카비르-함유 미립구를 함유하는 정제 등의 경구용 약학 조성물을 제공한다.

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07-07-2016 дата публикации

COMPOSITE TABLET FOR ORAL ADMINISTRATION COMPRISING MELATONIN AND SERTRALINE

Номер: WO2016108507A2
Принадлежит:

The present invention provides a composite tablet for oral administration and a method for manufacturing the same, the composite tablet for oral administration comprising: a sustained release layer including melatonin or a pharmaceutically acceptable salt thereof, and a gel-forming polymer as a sustained release agent; and an immediate release layer including sertraline or a pharmaceutically acceptable salt thereof.

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19-09-2019 дата публикации

POLMACOXIB-CONTAINING INJECTION COMPOSITION HAVING EXCELLENT STABILITY AND PREPARATION METHOD THEREFOR

Номер: WO2019177320A1
Принадлежит:

The present invention relates to a polmacoxib-containing injection solution and a preparation method therefor and to an injection composition in which polmacoxib, which is a poorly water-soluble nonsteroidal anti-inflammatory drug exhibiting an excellent effect even at a low dose, is solubilized and stabilized in an aqueous solution, and a preparation method therefor. According to the present invention, the utilization of a solubilizer and a stabilizer that are both available for injection agents allows the acquirement of a polmacoxib-containing injection composition excellent in stability without any deposition phenomenon.

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30-07-2020 дата публикации

INJECTION COMPOSITION CONTAINING FAB I INHIBITOR, AND PREPARATION METHOD THEREFOR

Номер: WO2020153723A1
Принадлежит:

The present invention relates to a pharmaceutical composition for intravenous administration, containing an Fab I inhibitor, and a preparation method therefor. The present invention can be effectively applied to an infection caused by antibiotic-resistant bacteria. Specifically, the present invention enables treatment effects to be more rapidly initiated by improving solubility and dissolution rate, and enables bioavailability to be improved. In addition, by controlling the size of particles, mixing and content uniformity of a preparation can be improved.

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03-10-2019 дата публикации

PHARMACEUTICAL COMPOSITION, COMPRISING POLMACOXIB AND PREGABALIN, FOR TREATMENT OF PAIN

Номер: WO2019190118A1
Принадлежит:

The present invention relates to a composite agent comprising polmacoxib and pregabalin. The present invention relates to a pharmaceutical composition and a drug or pain reliever, which each comprise the two active ingredients of polmacoxib and pregabalin and, more particularly, to a drug or pain reliever for treatment of moderately severe, acute, chronic, or neuropathic pain attributed to inflammation and various factors, an effect thereof, and a use thereof.

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