Настройки

Укажите год
-

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее
-

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Ведите корректный номера.
Укажите год
Укажите год
Применить Всего найдено 16. Отображено 16.
06-04-2017 дата публикации

MICRO PLASMA DEVICE FOR EYEBALL TREATMENT

Номер: KR101723956B1
Автор: PARK, CHAN HUM, PARK, HYUN JUNG, JU, HYUNG WOO, LEE, OK JOO, LEE, JUNG MIN, PARK, YE RI, YANG, JAE WOOK, LEE, HYE SOOK, LEE, YOON JIN, PARK, SUNG JIN
Принадлежит: INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY

The present invention relates to a micro plasma device for eyeball treatment including a micro plasma jet array (1a, 1b, 2, 3, 6) generating a micro plasma jet (7). The micro plasma device includes a safety cap (4) that is connected to at least a part of the micro plasma jet array, is provided with an inner space (8), and has an opening portion (9) on one side. The micro plasma jet (7) is injected into the inner space (8) of the safety cap (4). The micro plasma device for eyeball treatment according to the present invention can be used for treatment of a local area that has a curved shape or a micro treatment part such as an eyeball, is excellent in terms of stability and treatment effects, is much smaller than existing medical plasma devices, and is highly portable. COPYRIGHT KIPO 2017 ...

Подробнее
Номер записи: 1
01-06-2017 дата публикации

PRODUCTION METHOD OF COLLAGEN PATCH FOR EARDRUM REGENERATION, AND COLLAGEN PATCH FOR EARDRUM REGENERATION PRODUCED THEREBY

Номер: KR1020170060477A
Автор: PARK, CHAN HUM, KIM, SOO HYEON, LEE, OK JOO, JU, HYUNG WOO, LEE, JUNG MIN, MOON, BO MI, PARK, HYUN JUNG, PARK, YE RI, KIM, DONG WOOK, LEE, MIN CHAE, JEONG, JU YEON, KHANG, GIL SON
Принадлежит:

The present invention relates to a production method of a collagen patch for the regeneration of eardrum, and a collagen patch for the regeneration of eardrum produced by the production method. The production method comprises the steps of: (1) washing and cutting duck feet; (2) extracting acid-soluble collagen from the cut tissue of the duck feet in the step (1); (3) freeze-drying the acid-soluble collagen extracted in the step (2); (4) dissolving the collagen dried in the step (3) in an acid solution to prepare a collagen solution; (5) freezing the collagen solution obtained in the step (4); and freeze-drying the frozen collagen solution in the step (5). Accordingly, the production method of the present invention can provide a collagen patch for the regeneration of eardrum capable of reducing the regeneration time of eardrum in a patient with eardrum perforated by trauma or chronic disease, and inducing a boundary of the regenerated region to be regenerated cleanly while the thickness ...

Подробнее
Номер записи: 2
28-08-2015 дата публикации

CCTV CAMERA DEVICE AND STRUCTURE SUITABLE FOR USING SAME

Номер: KR101548341B1
Автор: KIM, BAE HOON, PARK, CHUN SEONG, JU, HYONG WOO, LEE, SEUNG HYONG
Принадлежит: YOUNG KOOK ELECTRONICS

The present invention relates to a camera device which is introduced to a large structure such as an LNG storage tank or an LNG carrier tank to stably obtain an image in the structure, and minimize the falling possibility of the camera device in the structure. According to the present invention, the camera device is installed at an upper end of the structure, is introduced into the structure through a guide pipe formed with a protrusion step at a lower end to prevent the camera device from being fallen down, thereby being suitable for photographing the inside of the structure, and comprises a main body, and an image photographing unit. A camera control unit circuit substrate is stored in the main body, and a plurality of protrusions which are hung above the protrusion step and a plurality of rolling wheels for preventing collision with the guide pipe are prepared at an outer circumferential surface. The image photographing unit is installed at a lower side of the main body. According to ...

Подробнее
Номер записи: 3
26-06-2017 дата публикации

PRODUCTION METHOD OF SILK FIBROIN BONE FIXATION DEVICE AND SILK FIBROIN BONE FIXATION DEVICE PRODUCED BY METHOD

Номер: KR101750984B1
Автор: PARK, CHAN HUM, KIM, SOO HYEON, KIM, DONG WOOK, MOON, BO MI, PARK, HYUN JUNG, PARK, YE RI, LEE, MIN CHAE, LEE, OK JOO, LEE, JUNG MIN, JEONG, JU YEON, JU, HYUNG WOO
Принадлежит: INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY

The present invention provides a production method of a silk fibroin bone fixation device, comprising a plate for fixing bone and a screw for fixing bone, produced from a water-soluble silk fibroin solution using a centrifugal separation method, and a silk fibroin bone fixation device produced by the method. According to the production method of a silk fibroin bone fixation device, the bone fixation device has a smooth surface and a compact structure without bubbles. COPYRIGHT KIPO 2017 ...

Подробнее
Номер записи: 4
18-07-2016 дата публикации

METHOD FOR PRODUCING FLUORESCENT SILK PROTEIN SOLUTION EXTRACTED FROM TRANSGENIC SILKWORM, AND METHOD FOR PRODUCING SUPPORT BY USING SAME

Номер: KR101640499B1
Автор: PARK, CHAN HUM, KIM, SOO HYEON, KIM, DONG WOOK, MOON, BO MI, PARK, HYUN JUNG, PARK, YE RI, LEE, MIN CHAE, LEE, OK JOO, LEE, JUNG MIN, JEONG, JU YEON, JU, HYUNG WOO
Принадлежит: INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY

The present invention provides a method for producing a fluorescent silk fibroin solution, wherein the method comprises the steps of: a) obtaining a refined fluorescent silk fibroin by adding a fluorescent silkworm in a solution including a refiner, by heating the same at 40-60°C for 8-24 hours, and by washing the same; b) dissolving the refined fluorescent silk fibroin in a solvent mixed with 15 mg to 1.5 g of dithiothreitol (DTT) for 9-9.6 M LiBr 100 ml at 40-60°C for 1-5 hours; and c) dialyzing the dissolved fluorescent silk fibroin in first distilled water for 48-96 hours. It is preferable the refiner includes alcalase and sodium hydrogen carbonate (NaHCO_3). A silk fibroin of a fluorescent silkworm cannot be dissolved at a low temperature through a convention method for producing a silk fibroin solution, and fluorescence is lost. However, according to the present invention, a reducing agent is added, and a fluorescent silk fibroin solution can be produced at a low temperature. Also ...

Подробнее
Номер записи: 5
06-04-2018 дата публикации

METHOD FOR PRODUCING SCAFFOLD FOR SUBSTITUTING DERMA, AND SCAFFOLD FOR SUBSTITUTING DERMA PRODUCED BY METHOD

Номер: KR1020180035381A
Автор: PARK, CHAN HUM, MOON, BO MI, PARK, HYUN JUNG, PARK, YE RI, LEE, OK JOO, LEE, JUNG MIN, JEONG, JU YEON, JU, HYUNG WOO, YEON, YEUNG KYU, KIM, SOON HEE
Принадлежит:

The present invention relates to a method for producing a scaffold for substituting derma, and a scaffold for substituting derma produced by the method. To this end, the method comprises the following steps: (1) producing an aqueous collagen solution by dissolving collagen derived from duck feet in an aqueous acid solution; (2) freezing the aqueous collagen solution; (3) producing a collagen sponge by primarily freeze-drying the frozen aqueous collagen solution in the step (2); and (4) removing acid components from the collagen sponge, and then secondarily freeze-drying the same. According to the present invention, the produced scaffold for substituting derma does not cause cell death when applied to affected skin, and helps skin layers healed in uniform thickness along with surrounding tissues, thereby being preferable without leaving scars. COPYRIGHT KIPO 2018 ...

Подробнее
Номер записи: 6
09-11-2015 дата публикации

METHOD FOR PRODUCING HYDROCOLLOID DRESSING FOR BURN TREATMENT, CONTAINING SILK FIBROIN NANOPARTICLES

Номер: KR1020150125137A
Автор: PARK, CHAN HUM, LEE, OK JOO, KIM, JUNG HO, LEE, JUNG MIN, JU, HYUNG WOO, MOON, BO MI, PARK, HYUN JUNG, KIM, DONG WOOK, LEE, MIN CHAE, KIM, SOO HYEON, RYU, HYUN SEUNG, SEO, JUN HYUK, PARK, CHO HEE
Принадлежит:

The present invention relates to a method for producing hydrocolloid dressing for burn treatment, containing silk fibroin nanoparticles and, more specifically, to a method for producing hydrocolloid dressing for burn treatment by mixing the silk fibroin nanoparticles, which are synthesized to be similar to a sphere with a smooth surface, along with a styrene-isoprene-styrene copolymer and sodium carboxymethylcellulose. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 7
30-03-2016 дата публикации

METHOD OF MANUFACTURING PLGA-SILK HYBRID STRUCTURE TO INDUCE BONE REGENERATION

Номер: KR1020160034557A
Автор: PARK, CHUM HUM, LEE, OK JOO, JU, HYUNG WOO, LEE, JUNG MIN, KIM, JUNG HO, MOON, BO MI, PARK, HYUN JUNG, KIM, DONG WOOK, LEE, MIN CHAE, KIM, SOO HYEON, JEONG, JU YEON
Принадлежит:

The present invention relates to a bone inductive artificial bone support including a silk protein, and a method of manufacturing the same. In addition, the present invention relates to an artificial bone support physically combined with a PLGA support by mixing a silk protein (or silk fibroin) extracted from cocoon or fibroin with hydroxyapatite nanoparticles. It is tried to replace a damaged bone tissue with a normal bone tissue or to regenerate a damaged bone tissue, and interests in the development of a bone tissue for implantation is increased. A method of implanting a bone of another person or an animal, or a method of implanting a tissue of a patient has been widely used, but the immunological rejection occurs or a damaged area is large by implanting a tissue of others. Therefore, a case in which a material which can be used in a body of a patient is not sufficient, might occur. Accordingly, the development of a safe artificial bone which can be easily supplied and manufactured in ...

Подробнее
Номер записи: 8
23-02-2017 дата публикации

METHOD FOR PREPARING FLUORESCENT SILK PROTEIN SOLUTION EXTRACTED FROM TRANSGENIC COCOONS AND METHOD FOR MANUFACTURING SCAFFOLD USING SAME

Номер: WO2017030277A1
Автор: PARK, Chan Hum, KIM, Soo Hyeon, KIM, Dong Wook, MOON, Bo Mi, PARK, Hyun Jung, PARK, Ye Ri, LEE, Min Chae, LEE, Ok Joo, LEE, Jung Min, JEONG, Ju Yeon, JU, Hyung Woo
Принадлежит:

The present invention provides a method for preparing a fluorescent silk fibroin solution, the method comprising the steps of: a) putting fluorescent cocoons in an aqueous solution containing a refining agent, followed by heating at 40-60℃ for 8-24 h and then washing with distilled water, thereby obtaining refined fluorescent silk fibroin; b) dissolving the refined fluorescent silk fibroin in a solvent, in which 15 mg to 1.5 g of dithiothreitol (DTT) is mixed with each 100 ㎖ of 9-9.6 M LiBr, at 40-60℃ for 1-5 h; and c) dialyzing the dissolved fluorescent silk fibroin in primary distilled water for 48-96 h. The refining agent preferably contains alcalase and sodium bicarbonate (NaHCO3). An existing method for preparing a silk fibroin solution from a fluorescent cocoon has disadvantages in that silk fibroin is not dissolved at a low temperature and the fluorescence is lost. However, according to the present invention, a method for adding a reductant has advantages in that a fluorescent silk ...

Подробнее
Номер записи: 9
16-01-2019 дата публикации

지혈용 다공성 스펀지 및 그 제조방법

Номер: KR1020190005593A
Автор: 박찬흠, 박현정, 박예리, 이옥주, 주형우, 서예빈, 이지승
Принадлежит:

... 본 발명은 지혈용 다공성 스펀지 및 그 제조방법에 관한 것으로서, 보다 상세하게는, 오리 발로부터 유래한 콜라겐과 실크를 혼합하여 제조할 수 있고, 지혈 특성 및 응고 특성이 우수한 지혈용 다공성 스펀지 및 그 제조방법에 관한 것이다. 이를 위해, 지혈용 다공성 스펀지는 콜라겐-실크 하이브리드 구조체를 포함하는 것을 특징으로 한다.

Подробнее
Номер записи: 10
07-04-2017 дата публикации

METHOD FOR PRODUCING BONE FIXING DEVICE, BONE FIXING DEVICE PRODUCED THROUGH METHOD, 3D PRINTER FILAMENT USED IN PRODUCING BONE FIXING DEVICE, AND METHOD FOR PRODUCING 3D PRINTER FILAMENT

Номер: KR1020170038444A
Автор: PARK, CHUM HUM, LEE, MIN CHAE, LEE, OK JOO, JU, HYUNG WOO, MOON, BO MI, LEE, JUNG MIN, PARK, HYUN JUNG, PARK, YE RI, KIM, DONG WOOK, KIM, SOO HYEON, JEONG, JU YEON
Принадлежит:

The present invention relates to a method for producing a bone fixing device, to a bone fixing device produced through the method, to a 3D printer filament used in producing the bone fixing device, and to a method for producing the 3D printer filament. The method for producing a bone fixing device comprises the steps of: a tomogram image photographing step of obtaining tomogram image data by photographing a fraction part of a patient by a medical tomogram image photographing device; a 3D modeling step of generating 3D data with respect to a bond fixing device corresponding to the fraction part on the basis of the image data; a raw ingredient supplying step of supplying a filament including polylactic acid (PLA) and hydroxyapatite (HA) to a 3D printer; and a bone fixing device producing step of performing 3D printing on a bone fixing device through the 3D printer by using the 3D data. According to the present invention, a patient-customized bone fixing device capable of performing a bone ...

Подробнее
Номер записи: 11
01-04-2016 дата публикации

PRODUCING METHOD OF THREE DIMENSIONAL POROUS SILK FIBROIN SCAFFOLDS FOR TISSUE AND BONE REGENERATION

Номер: KR1020160035917A
Автор: PARK, CHAN HUM, MOON, BO MI, PARK, HYUN JUNG, LEE, OK JOO, JU, HYUNG WOO, LEE, JUNG MIN, KIM, JUNG HO, KIM, DONG WOOK, LEE, MIN CHAE, KIM, SOO HYEON
Принадлежит:

The present invention relates to a producing method of three dimensional porous silk fibroin scaffolds for tissue and bone regeneration through a salt leaching method using salt and sucrose. The producing method of three dimensional porous scaffolds for tissue and bone regeneration comprises the steps of: mixing a silk fibroin aqueous solution and sucrose, salt, or a mixed salt of sucrose and salt as salts; drying a mixture of the silk fibroin aqueous solution and the salts; removing the salts by immersing the mixture in distilled water; and forming scaffolds by drying the mixture removing the salts. The three dimensional porous scaffolds have a bone regeneration effect and mechanical properties. COPYRIGHT KIPO 2016 ...

Подробнее
Номер записи: 12
30-08-2016 дата публикации

조직 및 뼈 재생을 위한 실크 피브로인 다공성 3차원 지지체 제작 방법

Номер: KR0101652582B1
Автор: 박찬흠, 문보미, 박현정, 이옥주, 주형우, 이정민, 김정호, 김동욱, 이민채, 김수현
Принадлежит: 한림대학교 산학협력단

... 본 발명은 소금과 자당을 이용한 염 침출법을 통해 조직 및 뼈 재생을 위한 실크 피브로인 (또는 실크 단백질) 다공성 3차원 지지체의 제작 방법에 관한 것이다. 조직공학은 생체 내 결손된 장기 및 조직의 재생을 위해 적절한 지지체를 이식하거나 조직 세포를 체외 배양하여 실제 장기나 조직과 유사한 구조와 기능을 가지는 인공 조직을 이식하여 인체 기능의 복원을 목적으로 한다. 따라서 생체재료를 조직 공학용 지지체로 활용하기 위해서는 다공성 구조를 형성해야 한다. 이는 생체재료 자체에 적절한 공극을 지니면 세포의 생장에 필요한 공간을 제공할 수 있으며 공극이 서로 연결되어 개방된 통로를 만들면 세포간 영양분, 대사 물질 및 가스 교환이 원활하게 된다. 또한 성공적인 조직의 유지 및 복원을 위해서는 만들어진 생체재료에 세포의 부착, 증식, 세포외 기질 형성과 동시에 생체 재료를 분해하는 속도 조절이 중요하다. 실크 피브로인은 누에고치에서 세리신을 제거 한 천연 고분자로서 대량 생산이 가능한 단백질이며 FDA에서 안전성이 입증되었고, 다른 합성 고분자들과는 다르게 체내에서 면역반응이 일어나지 않고 염증반응이 적어 생체적합성이 우수하며 결정화도에 따라 분해 속도를 조절 할 수 있어 생화학 및 의학적 응용이 활발한 의료용 소재이다. 이러한 실크 피브로인을 이용해 3차원 다공성지지체를 제작하는 방법으로는 캐스팅 방법, 전기방사, 염 침출법 등이 있다. 그 중 염 침출법에 관한 연구는 활발히 진행되어왔으나, 실크 피브로인 수용액을 이용하여 지지체를 제작하기에는 기계적 강도가 약하고, 염 제거 후 동결건조 과정을 거쳐 제작 시간이 오래 걸리는 등의 제한점이 있다. 본 발명에서는 이러한 단점을 보완하여 기계적 물성을 강화하고, 연골 조직의 분화와 골 재생 효과가 우수한 지지체를 제작하였다. 따라서 본 발명에 따른 제조방법으로 제작된 실크 피브로인다공성 3차원 지지체는 조직 재생용 지지체 뿐만 아니라 정형외과적 인공 뼈, 치주 조직 재생 유도재 및 골 이식재 등으로 활용될 수 있다.

Подробнее
Номер записи: 13
28-06-2016 дата публикации

FILTER FOR PORTABLE PERITONEAL DIALYSIS LIQUID REGENERATING SYSTEM USING ENZYME-INCLUDED SILK FIBROIN AND METHOD FOR PRODUCING SAME

Номер: KR101634205B1
Автор: PARK, CHAN HUM, SUNG, GUN YONG, LEE, OK JOO, MOON, BO MI, JU, HYUNG WOO, LEE, JUNG MIN, KIM, JUNG HO, PARK, HYUN JUNG, KIM, DONG WOOK, LEE, MIN CHAE, KIM, SOO HYEON, JEONG, JU YEON
Принадлежит: INDUSTRY ACADEMIC COOPERATION FOUNDATION, HALLYM UNIVERSITY

The present invention relates to a method for producing a filter for a peritoneal dialysis liquid regenerating system by using a silk fibroin or a silk protein and, more specifically, to a filter including an enzyme such as urease in a silk fibroin or a silk protein and to a method for producing a filter for a portable peritoneal dialysis liquid regenerating system. A silk fibroin does not cause in vivo immunoreactions compared to other polymers, and safety thereof has been recognized by FDA, so the silk fibroin is used as a medical material for a suturing yarn or the like. The filter according to the present invention effectively removes a low molecular material and may very effectively regenerate a peritoneal dialysis liquid. Moreover, the filter may be simultaneously used with a conventional activated carbon filter, so a peritoneal dialysis liquid may be more effectively regenerated. A sink fibroin filter according to the present invention has advantages such as mass-productivity, adjustable ...

Подробнее
Номер записи: 14
06-10-2016 дата публикации

FILTER FOR PORTABLE PERITONEAL DIALYSATE REGENERATION SYSTEM USING ENZYME-INCLUDED SILK FIBROIN AND METHOD FOR MANUFACTURING SAME

Номер: WO2016159500A1
Автор: PARK, Chan Hum, SUNG, Gun Yong, LEE, Ok Joo, MOON, Bo Mi, JU, Hyung Woo, LEE, Jung Min, KIM, Jung Ho, PARK, Hyun Jung, KIM, Dong Wook, LEE, Min Chae, KIM, Soo Hyeon, JEONG, Ju Yeon
Принадлежит:

The present invention relates to a method for manufacturing a filter for a peritoneal dialysate regeneration system, using silk fibroin or silk protein and, more specifically, to a filter comprising silk fibroin or silk protein including an enzyme such as urease therein and to a method for manufacturing a filter for a portable peritoneal dialysate regeneration system. Silk fibroin, unlike the other polymers, does not induce an immune response in vivo, and was approved to be safe by FDA, and thus silk fibroin has been used for other medical materials including a suture thread. The filter according to the present invention can regenerate a peritoneal dialysate very effectively by effectively removing low-molecular materials. In addition, the filter of the present invention can be used simultaneously with an existing activated carbon filter, thereby allowing more effective regeneration of dialysate. The silk fibroin filter according to the present invention has advantages of mass productivity ...

Подробнее
Номер записи: 15
30-03-2016 дата публикации

ARTIFICIAL SKIN MANUFACTURED BY USING 3D SILK FIBROIN ELECTROSPINNING METHOD

Номер: KR1020160034564A
Автор: PARK, CHUM HUM, LEE, OK JOO, JU, HYUNG WOO, LEE, JUNG MIN, KIM, JUNG HO, MOON, BO MI, PARK, HYUN JUNG, KIM, DONG WOOK, LEE, MIN CHAE, KIM, SOO HYEON, JEONG, JU YEON
Принадлежит:

The present invention relates to a method of selecting and manufacturing a pore size suitable for an artificial skin and a support capable of easily manufacturing an artificial skin after electrospinning silk fibroin (or silk protein) through a novel electrospinning method. According to the present invention, silk fibroin used when an artificial skin is manufactured, is a natural polymer which can be obtained from a silkworm. The silk fibroin is a natural polymer protein which can be mass-produced, and is capable of being obtained through a sericin removing method. The silk fibroin is a polymer which does not induce an immune response unlike other synthetic materials, and the usage of the silk fibroin is approved as a medical material by the FDA. In addition, the silk fibroin used as a medical material including a suture and other medical materials from the past, is a natural polymer whose safety is proved. Therefore, various materials using the silk fibroin have been developed as a medical ...

Подробнее
Номер записи: 16