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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 108. Отображено 100.

15-03-2017 дата публикации

열 차단 지수의 생성 방법

Номер: KR0101716325B1

Автор: 손의동, 김현정, 김지현, 최현정, 남개원, 이태룡, 정진호, 진선필

Принадлежит: (주)아모레퍼시픽, 서울대학교산학협력단

... 열 차단 지수의 생성 방법은, 열 차단 물질이 도포된 제1 영역 및 상기 열 차단 물질이 도포되지 않은 제2 영역에 각각 열을 가하는 단계; 상기 제1 영역 및 제2 영역 각각의 포화 온도를 측정하는 단계; 상기 제1 영역에 가해진 열에 대응되는 에너지를 상기 제1 영역의 포화 온도로 나누어 제1 에너지를 산출하는 단계; 상기 제2 영역에 가해진 열에 대응되는 에너지를 상기 제2 영역의 포화 온도로 나누어 제2 에너지를 산출하는 단계; 및 상기 제1 에너지를 상기 제2 에너지로 나누거나, 또는 상기 제1 에너지 및 상기 제2 에너지의 차를 상기 제1 에너지로 나누어 상기 열 차단 물질의 열 차단 지수를 산출하는 단계를 포함할 수 있다.

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Номер записи: 1

12-06-2017 дата публикации

CRISPR/CAS9 시스템을 이용한 프로히비틴2 유전자 제거용 시발체

Номер: KR0101745863B1

Автор: 신명근, 최현정

Принадлежит: 전남대학교산학협력단

... 본 발명의 CRISPR/CAS9 시스템을 이용한 프로히비틴2 유전자 제거 방법 및 이에 사용되는 시발체는 프로히비틴2 유전자만이 선택적으로 정확히 제거되도록 특별히 디자인됨으로써, 비표적 유전자에는 영향을 주지 않으면서 표적 유전자인 프로히비틴2 유전자만이 특이적으로 정확하게 제거되어 제거 효율이 현저하게 향상되는 효과가 있다.

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Номер записи: 2

08-10-2015 дата публикации

Cosmetic composition containing Phyllanthus urinaria extrancts

Номер: KR0101558186B1

Автор: 손의동, 최현정, 김지현, 문성준, 김한곤

Принадлежит: (주)아모레퍼시픽

... 본 발명은 항노화, 항산화 또는 주름개선 효과를 갖는 화장료 조성물에 관한 것으로서, 보다 상세하게는 여우구슬 추출물을 유효성분으로 함유함으로써 피부에서 콜라겐생성을 촉진하며, MMP-1을 억제하고, DNA 손상을 보호하며, 사이클로옥시게나제-2의 생합성을 억제하고, 종양괴사인자-α의 생합성을 억제하여 항노화, 항산화 또는 주름개선 효과를 갖는 화장료 조성물에 관한 것이다.

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Номер записи: 3

08-06-2015 дата публикации

FLAT BENCH USING GABION

Номер: KR1020150062873A

Автор: CHOI, HYEON JEONG

Принадлежит:

The present invention relates to a flat bench supporting buttocks and a femoral region of a human body and enabling relaxation while sitting and, more specifically, to a flat bench using a gabion, which comprises: a plurality of vertical support rods fixedly vertically installed on the ground at a consistent distance; an upper frame installed in the vertical support rods for buttocks and a femoral region of a human body to be supported; and a gabion wherein a filling material such as a pebble, stone, or the like slopingly inserted into the vertical support rods. Thus, construction of a gabion is simply performed to enable a bench and a natural environment to harmonize, thereby developing an aesthetic to improve efficiency thereof. COPYRIGHT KIPO 2015 ...

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Номер записи: 4

17-05-2018 дата публикации

METHOD FOR TRANSMITTING RRC MESSAGE AND WIRELESS DEVICE

Номер: WO2018088756A1

Автор: KIM, Jaehyun, KIM, Taehun, CHOE, Hyunjung, PARK, Sangmin

Принадлежит:

A disclosure of the present specification provides a method for transmitting a radio resource control (RRC) message by a wireless device. The method may comprise the steps of: acquiring, by an access stratum (AS) layer of a wireless device, at least one of the value and indication of an RRC establishment cause field from a non-access stratum (NAS) layer which requests transmission of an NAS signaling request message; transmitting, to a base station, an RRC connection request message including the at least one of the value and indication of the RRC establishment cause field; and when the at least one of the value and indication of the RRC establishment cause field is set to a value, which indicates that the NAS signaling request message includes user data, according to an optimization scheme through a control plane (CP), if a network is in an overload state, receiving an RRC connection rejection message or an RRC connection release request message from the base station.

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Номер записи: 5

08-10-2018 дата публикации

보글리보스를 포함하는 피부 미백용 조성물

Номер: KR0101904920B1

Автор: 빈범호, 최현정, 양승하, 주경미, 조영석, 조은경, 이태룡

Принадлежит: (주)아모레퍼시픽

... 본 발명은 멜라닌 생성을 억제 또는 저해시키는 피부 미백용 조성물에 관한 것으로서, 구체적으로 발리올아민(valiolamine) 유도체를 포함하는 피부 미백용 조성물에 관한 것이다.

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Номер записи: 6

16-12-2016 дата публикации

양초 제조방법 및 그에 의한 양초

Номер: KR0101687170B1

Автор: 최현정

Принадлежит: 최현정

... 본 발명은 양초 제조방법 및 그에 의한 양초에 관한 것으로, 보다 구체적으로는 양초 제조방법 및 그에 의한 양초에 관한 것이다. 상기 방법은; 본 발명은 소이왁스를 준비하는 단계; 준비된 소이왁스를 가열하여 액화시키는 단계; 액상의 소이왁스를 형틀을 이용하여 심지가 끼워진 양초본체를 성형하는 단계; 액상의 소이왁스에 응고지연제를 넣고 교반하는 단계; 교반된 액상 소이왁스를 압출기구에 넣고 짜면서 소이왁스로써 입체적 형태로 된 장식부를 성형하여 상기 양초본체의 위에 적층 성형하는 단계;를 포함하는 것을 특징으로 한다.

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Номер записи: 7

01-03-2018 дата публикации

SKIN-WHITENING COMPOSITION CONTAINING CYTOCHALASIN D

Номер: WO2018038425A1

Автор: CHOI, Hyun Jung, BAE, Il Hong, KIM, Hyoung June, LEE, Young Jin, LEE, Tae Ryong, CHO, Dong-Hyung, SHIN, Ji Hyun, SHIN, Dong Woon

Принадлежит:

One aspect of the present invention relates to a skin-whitening composition containing, as an active ingredient, cytochalasin D, optical or stereoscopic isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof. Through the one aspect of the present invention, a novel whitening material can be provided to consumers and development of skin whitening-related industries can be promoted.

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Номер записи: 8

11-10-2018 дата публикации

METHOD FOR DETERMINING NUCLEIC ACID QUALITY OF BIOLOGICAL SAMPLE

Номер: WO2018186687A1

Автор: SHIN, Young Kee, KIM, Jin Ju, KIM, Sung Su, CHOI, Hyun Jeung, MOON, Young Ho, KIM, Myung Sun, KIM, Jee Eun

Принадлежит:

The present invention relates to a method for determining the DNA quality of a biological sample and, more specifically, to a method for determining the DNA quality of a biological sample by performing a quantitative polymerase chain reaction (PCR) using primers capable of amplifying a target gene, a method for preparing the primers used in the method, and a method for standardizing the amount of detected target gene mutation by using the determined DNA quality. The method of the present invention enables objective evaluation of the DNA quality of a biological sample used in gene analysis and the presentation of objective results on the expression ratio of a gene mutation, thereby providing reliable information in the fields of clinical research and companion diagnosis.

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Номер записи: 9

21-05-2018 дата публикации

순환 종양 세포를 이용한 암 환자의 2차 치료용 치료제 반응성 진단 방법

Номер: KR0101850495B1

Автор: 신영기, 오명렬, 최준석, 조상래, 정경숙, 변보현, 김진주, 김성수, 최현정

Принадлежит: 서울대학교산학협력단, 주식회사 젠큐릭스

... 본 발명은 순환 종양 세포를 이용한 암 환자의 2차 치료용 치료제 반응성 진단 방법에 관한 것으로, 보다 상세하게는 암 환자의 유전자 변이 정보 검출을 통한 2차 치료 (second line treatment) 판단을 위한 정보를 제공하기 위하여, 환자의 혈액 시료로부터 CTC를 분리하여 검출하는 여러 단계를 포함하는 치료 반응성 예측치를 산출하는 방법으로 자동화에 적합한 방법에 관한 것이다. 본 발명의 방법은 FFPE 조직 시료를 얻기 어려운 2차 치료 대상의 환자의 혈액을 이용하여 치료 반응성 예측치를 산출하여, 환자의 치료제에 대한 반응성 예측, 진단이 가능하므로 항암치료제의 투여 필요성 판단을 비롯하여 향후 치료의 방향에 대한 단서를 제시하는 목적으로 유용하게 사용할 수 있다.

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Номер записи: 10

09-11-2017 дата публикации

CRISPR/CAS9 시스템을 이용한 베타2-마이크로글로불린 유전자 제거용 시발체

Номер: KR0101795999B1

Автор: 신명근, 최현정

Принадлежит: 전남대학교산학협력단

... 본 발명의 CRISPR/CAS9 시스템을 이용한 베타2-마이크로글로불린 유전자 제거 방법 및 이에 사용되는 시발체는 베타2-마이크로글로불린 유전자만이 선택적으로 정확히 제거되도록 특별히 디자인됨으로써, 비표적 유전자에는 영향을 주지 않으면서 표적 유전자인 베타2-마이크로글로불린 유전자만이 특이적으로 정확하게 제거되어 제거 효율이 현저하게 향상되는 효과가 있다.

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Номер записи: 11

04-02-2016 дата публикации

SKIN WHITENING COMPOSITION CONTAINING CHEMOKINE

Номер: WO2016018001A1

Автор: LEE, Eun Kyung, HAN, Ji Yeon, CHO, Eun Gyung, LEE, Tae Ryong, CHOI, Hyun Jung

Принадлежит:

The present invention relates to a composition containing a chemokine, especially, an interferon-inducible T-cell alpha chemoattractant (ITAC) so as to decrease the gene expression of a factor related to melanin pigment formation in a melanin-forming cell, thereby exhibiting a skin whitening effect.

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Номер записи: 12

26-01-2017 дата публикации

CHISEL FOR BREAKER AND METHOD FOR MANUFACTURING SAME

Номер: WO2017014481A1

Автор: YOO, Jang Ho, YOO, Byong Seop, YOO, Da Eun, CHOI, Hyun Joung

Принадлежит:

Disclosed are a chisel for a breaker and a method for manufacturing the same. A chisel for a breaker according to an embodiment of the present invention comprises: an installation part installed in a breaker body; and a work part having a mountain-shaped hitting part arranged at the tip end thereof, wherein the work part comprises a central part having a relatively high hardness by hardening heat treatment and a circumferential part having hardness lower than that of the central part by softening heat treatment.

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Номер записи: 13

27-12-2012 дата публикации

COMPOSITION FOR CONTROLLING CHROMOGENESIS INCLUDING MICRORNA

Номер: WO2012177008A3

Автор: KIM, Kyu Han, CHOI, Hyun Jung, BIN, Bum Ho, LEE, Tae Ryong

Принадлежит:

The present invention relates to a composition for a whitening effect or for the prevention of gray hair, which comprises antisense nucleic acid molecules of sequence number 2, wherein the composition has an miRNA of sequence number 1 or a base sequence complementary to the miRNA of sequence number 1 and can be hybridized to the miRNA. The present invention further relates to a method for not only controlling chromogenesis in test materials but also for screening for expression control materials of chromogenic genes, the method comprising the steps of: transfecting, to a cell, the miRNA of sequence number 1 or the antisense nucleic acid molecules of sequence number 2; treating the test materials in the cell; confirming whether or not the test materials inhibit or promote the expression of the chromogenic genes; and confirming whether or not the color of the cell is changed. The composition and the screening method, according to the present invention, can be used for the whitening effect ...

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Номер записи: 14

03-01-2019 дата публикации

액세스 금지 체크를 수행하는 방법 및 장치

Номер: KR1020190000890A

Автор: 이영대, 최현정

Принадлежит:

... 무선 통신 시스템에서 단말이 액세스 금지 체크(access barring check)를 수행하는 방법 및 이를 지원하는 장치가 제공된다. 상기 방법은, 금지 정보(barring information)의 리스트를 수신하되, 상기 각각의 금지 정보는 금지 팩터(barring factor) 및 금지 시간(barring time)을 포함하는 단계; 상기 리스트에 포함된 금지 정보와 관련된 액세스 카테고리(access category)에 대한 정보를 수신하는 단계; 상기 액세스 카테고리와 관련된 상기 금지 정보를 기반으로, 상기 액세스 카테고리에 대한 상기 액세스 금지 체크를 수행하는 단계; 및 상기 액세스 카테고리에 대하여 액세스 시도(access attempt)가 허용되면, 상향링크 전송을 수행하는 단계;를 포함할 수 있다.

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Номер записи: 15

30-11-2016 дата публикации

METHOD FOR MANUFACTURING ELECTRICAL CONTACT MATERIAL CONTAINING SILVER-COATED CARBON NANO TUBE

Номер: KR1020160137178A

Автор: CHO, WOOK DONG, MOON, CHUL DONG, CHOI, HYEON JEONG, KIM, WON YOUNG, BAIK, SEUNG HYUN, LEE, DONG MOK, SIM, JEONG HYUN

Принадлежит:

The present invention relates to a method for manufacturing an electrical contact material containing a silver-coated carbon nano tube including: (a) a step in which ultrasonic dispersion and acid treatment are performed with the carbon nano tube in a silver nitrate solution; (b) a step in which the carbon nano tube is washed after the ultrasonic dispersion and acid treatment in Step (a); (c) a step in which the washed carbon nano tube is sequentially mixed with a tin chloride-hydrochloric acid solution and a palladium chloride-hydrochloric acid solution and then ultrasonic application is performed so that tin and palladium are bonded to the surface of the carbon nano tube; (d) a step in which a silver nitrate aqueous solution and an ammonia aqueous solution are put in and mixed until the color is removed and then the carbon nano tube produced in Step (c) is mixed; (e) a step in which a glyoxylic acid aqueous solution and a sodium hydroxide aqueous solution are mixed with each other and ...

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Номер записи: 16

18-09-2014 дата публикации

METHOD FOR SCREENING SUBSTANCE HAVING WHITENING EFFICACY

Номер: WO2014142552A1

Автор: KIM, Jue Won, CHOI, Hyun Jung, LEE, Tae Ryong, CHO, Eun Gyung

Принадлежит:

The present invention relates to a method for screening a substance having a whitening efficacy and, more particularly, to a method for screening a substance having a whitening efficacy, the method characterized by checking whether or not a test substance activates Forkhead box O3A (FoxO3a) or promotes the expression thereof, using FoxO3a, which is a longevity gene, and thereby determining whether or not the test substance has a whitening efficacy.

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Номер записи: 17

08-04-2016 дата публикации

a gabion wall

Номер: KR0101610816B1

Автор: 최현정

Принадлежит: 최현정

... 본 발명은 돌이나 자갈 등의 채움재를 그 내부에 수납하여 구성되는 돌망태를 외부측에 고정하여 설치하는 개비온(gabion)벽체에 관한 것으로, 더욱 상세하게는 건축물 벽체부재나 콘크리트 구조물의 외측에 다수 개의 지지프레임을 설치 고정하되 상기 지지프레임에 지면과 수직한 방향으로 일정한 간격의 끼움부를 형성하고 상기 끼움부에 채움재가 수납되는 돌망태를 삽설하여 외벽이 형성되도록 구성함으로써, 외부에 벽체부재나 콘크리트 구조물 및 이를 지지하는 프레임이 그대로 노출되는 것을 방지하면서 미려함을 제공함은 물론 자연과의 조화를 이루도록 하여 그 활용성을 한층 높여줄 수 있도록 하는 돌망태를 이용한 조립식 개비온벽체에 관한 것이다. 또한 본 발명은 콘크리트의 구조물이 없는 철골구조물 등에도 유용하게 적용될 수 있어 건축물의 벽체시공에 매우 유용하게 활용된다.

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Номер записи: 18

08-06-2016 дата публикации

COMPOSITION FOR INDUCING CELL REJUVENATION COMPRISING GENISTEIN OR EPIGALLOCATECHIN GALLATE

Номер: KR1020160065035A

Автор: LEE, EUN KYUNG, GOH, MYEONG JIN, CHOI, HYUN JUNG, CHO, EUN GYUNG, LEE, TAE RYONG

Принадлежит:

The present invention relates to novel use of genistein, epigallocatechin gallate (EGCG), a derivative thereof, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof and a solvate thereof. A composition comprising genistein, EGCG, a derivative thereof, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof and a solvate thereof reduces expression of a factor related with an increase in melanin pigment formability, reduces expression of aging status protein and controls expression of enzymes related with melanin pigment formation, and thus is effective for rejuvenation of cells including melanin cells. COPYRIGHT KIPO 2016 (AA) Comparison of mRNA expression of p16 (BB) Comparison of mRNA expression of p21 ...

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Номер записи: 19

02-05-2019 дата публикации

ANTIAGING COMPOSITION COMPRISING CYTOCHALASIN D OR SAG, AND METHOD FOR SCREENING ANTIAGING SUBSTANCE

Номер: WO2019083132A1

Автор: CHOI, Hyun Jung, KIM, Hyoung June, JUNG, Ji Yong, LEE, Tae Ryong

Принадлежит:

The present description relates to an antiaging composition comprising cytochalasin D or SAG, and a method for screening an antiaging substance, and provides a new antiaging substance and a new method for discovering a new antiaging substance. Thus, it is possible to greatly contribute to the development of beauty industries and to meeting demands related to beauty and antiaging, if the present description is effectively used.

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Номер записи: 20

09-02-2017 дата публикации

LOVE CHAIR

Номер: WO2017022977A1

Автор: YOO, Jang Ho, YOO, Byong Seop, YOO, Da Eun, CHOI, Hyun Joung

Принадлежит:

A love chair is disclosed. The love chair according to one embodiment of the present invention comprises: a base; a chair disposed on one side of the base and angle-adjustable with an upper body support portion rotatable with respect to a lower body support portion; a stand disposed on the other side of the base, away from the chair, and higher than at least the lower body support portion of the chair; and a footrest disposed under the stand, wherein the chair and the stand can move up and down with respect to the footrest and toward or away from each other.

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Номер записи: 21

04-03-2010 дата публикации

OBJECT RECOGNITION SYSTEM, WIRELESS INTERNET SYSTEM HAVING SAME, AND OBJECT-BASED WIRELESS COMMUNICATION SERVICE METHOD USING SAME

Номер: WO2010024584A3

Автор: SHIN, Eui Hyun, CHOI, Hyun Jeong, PARK, Sung Yong

Принадлежит:

An object recognition system includes a virtual object database and a virtual target object determination part. In the virtual object database are stored a plurality of virtual objects consisting of an attribute data set and a service data set. The virtual target object determination part computes the attribute values of an actual target object upon receiving a transmission of actual object recognition data of a previewed actual target object, and it determines as the target virtual object, that virtual object having attribute values that match the attribute values of the actual target object computed for a plurality of virtual objects stored in the virtual object database. In this way, the object recognition system provides service data related to the previewed actual object. Accordingly, it can provide a wireless communication method that surpasses the concept of the existing Internet and is based on actual objects, can form a simple and intuitive wireless Internet environment, and that ...

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Номер записи: 22

18-01-2017 дата публикации

COMPOSITION FOR PREPARING SAUCE, PREPARATION METHOD OF SAUCE USING SAME, AND SAUCE

Номер: KR101697281B1

Автор: KONG, BYUNG CHON, CHOI, JUNG RYONG, CHOI, HYUN JUNG

Принадлежит: SHINSEGAE FOOD INC.

Provided are a composition for preparing a sauce, a preparation method of a sauce using the same, and a sauce prepared according to the preparation method. The composition for preparing a sauce comprises: purified water; black pepper; cayenne pepper; chili powder; allspice powder; garlic; lemon; cumin; paprika seasoning; salt; vinegar; coriander seeds; chicken broth; pepperoncini; and capsaicin. COPYRIGHT KIPO 2017 ...

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Номер записи: 23

28-12-2017 дата публикации

POWER STRIP HAVING LINE OF WHICH LENGTH CHANGES FREELY

Номер: KR1020170142589A

Автор: CHOI, HYUN JUNG

Принадлежит:

The present invention relates to a power strip having a line of which the length changes freely to be used more conveniently. COPYRIGHT KIPO 2018 ...

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Номер записи: 24

31-07-2014 дата публикации

GRAPHENE COUNTER ELECTRODE FOR DYE-SENSITIZED SOLAR CELL, METHOD FOR MANUFACTURING SAME, AND DYE-SENSITIZED SOLAR CELL COMPRISING SAME

Номер: WO2014116026A1

Автор: KIM, Hwan-Kyu, JU, Myung-Jong, CHOI, In-Taek, KIM, Sang-Gyun, KIM, Jae-Cheon, LEE, Jae-Joon, BAEK, Jong-Beom, JEON, In-Yup, CHOI, Hyun-Jung

Принадлежит:

The present invention relates to a graphene counter electrode for a dye-sensitized solar cell, a method for manufacturing same, and a dye-sensitized solar cell comprising same, the method comprising the steps of: a) manufacturing a graphene compound onto which nitrogen elements are doped by doping nitrogen on graphite; and b) surface-treating an FTO transparent electrode with the graphene compound manufactured in step a) by using electrostatic spray deposition.

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Номер записи: 25

25-04-2013 дата публикации

SYSTEM FOR SCREENING SKIN-WHITENING MATERIAL

Номер: WO2013058578A2

Автор: LEE, Ai Young, LEE, Tae Ryong, CHOI, Hyun Jung

Принадлежит:

Disclosed are a system for screening a skin-whitening material comprising one or more layers which include one or more cells of fibroblasts, keratinocytes, and melanocytes, and a method for screening a skin-whitening material using the system. In addition, the invention presents a composition for skin whitening which comprises a material screened by the method for screening a skin- whitening material as an active ingredient.

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Номер записи: 26

25-11-2010 дата публикации

SEMANTIC SEARCH METHOD AND SYSTEM IN WHICH A PLURALITY OF CLASSIFICATION SYSTEMS ARE LINKED

Номер: WO2010134752A3

Автор: CHOI, Hyun Jung, SHIN, Chang Ho, LEE, You Jin, LEE, Seung Beom, LEE, Min Jung

Принадлежит:

In the semantic search method according to the present invention, a database is created from resources corresponding to various classification categories for various divided classification systems obtained by dividing up, into two or more divisions, a classification system having a plurality of classification categories, and associative relationships between two classification categories are established based on similarity values of a first classification category in a first classification system and a second classification category in a second classification system for various keywords such that, when search results for input keywords are provided, the search results can be provided with the resources belonging to a plurality of classification systems divided up by each classification system or by each classification category based on the associative relationships.

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Номер записи: 27

05-12-2017 дата публикации

COMPOSITION FOR DETECTING EPIDERMAL CELL GROWTH FACTOR RECEPTOR GENE MUTATION, AND KIT COMPRISING SAME

Номер: KR1020170133285A

Автор: SHIN, YOUNG KEE, BYUN, BO HYUN, CHOI, HYUN JEUNG, CHOI, JOON SEOK, MOON, YOUNG HO, LEE, JONG HEUN, CHO, SANG RAE, KIM, JEE EUN, KIM MYUNG SUN

Принадлежит:

The present invention relates to a composition for detecting an epidermal cell growth factor receptor gene mutation and to a kit comprising the composition and, more specifically, to a primer and probe set composition for detecting an epidermal cell growth factor gene mutation, and to a kit for detecting an EGFR gene mutation, comprising the composition. The method according to the present invention can not only predict and diagnose responsiveness to a therapeutic agent for the prognosis of a cancer patient, but also predict a cancer metastasis or relapse. Thus, the method can be useful for the purposes of determining the need to administer an anticancer therapeutic agent and guiding the direction of future treatment, and for monitoring a cancer metastasis or relapse. COPYRIGHT KIPO 2017 ...

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Номер записи: 28

26-10-2015 дата публикации

SKIN-IMPROVING MATERIAL CAPABLE OF CONTROLLING EXPRESSION OF CADHERIN 11 OR N-CADHERIN AND METHOD FOR SCREENING SAME

Номер: KR1020150119741A

Автор: LEE, AI YOUNG, KIM, NAN HYUNG, LEE, TAE RYONG, CHOI, HYUN JUNG, LEE, EUN KYUNG, CHO, EUN GYUNG

Принадлежит:

The present invention provides a skin-improving composition including a material, as an active material, for inhibiting expression of at least one from cadherin 11 and N-cadherin, and a skin-improving kit including the same. According to the present invention, cutaneous hyperpigmentation can be alleviated; a skin whitening effect can be provided; and an excellent anti-aging effect can be provided as the skin-improving composition can prevent or alleviate generation of wrinkles. The present invention provides a system for screening a skin-improving material including a co-culture product of at least two from fibroblast, keratinocyte and melanocyte, and a method for screening a skin improving material. The method includes the steps of: treating the co-culture product of the system for screening a skin-improving material with candidate materials; and measuring change of expression of at least one from cadherin 11 and N-cadherin. The change of expression of at least one from cadherin 11 and ...

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Номер записи: 29

07-12-2017 дата публикации

CONTAINER OF COSMETIC PRODUCT

Номер: KR101806524B1

Автор: LI, YAN, CHOI, SUN KYUNG, KIM, EUN JEONG, KIM, HYUN HEE, CHOI, HYUN JUNG

Принадлежит: AMOREPACIFIC CORPORATION

The present invention relates to a container of a cosmetic product comprising: a body; a first applicator; a second applicator; and a selective permeable membrane. The body stores a first solution and a second solution, which include different density, and are separated from each other in an original state by a density difference in a mixed state, in one storing space. The first applicator is provided on one side of the body; and applies the first solution, or a mixed solution in which the first solution and the second solution are mixed. The second applicator is provided on the other side of the body; and applies the second solution. The selective permeable membrane is provided inside the body; blocks movement of the first solution to the second applicator; and passes the second solution. The container of the cosmetic product provides a cosmetic material having various features. COPYRIGHT KIPO 2017 ...

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Номер записи: 30

22-03-2017 дата публикации

METHOD FOR FABRICATING ELECTRICAL CONTACT MATERIALS COMPRISING SILVER-COATED CARBON NANOTUBES

Номер: KR1020170032261A

Автор: KIM, WON YOUNG, MOON, CHUL DONG, CHOI, HYEON JEONG, CHO, WOOK DONG, BAIK, SEUNG HYUN, LEE, DONG MOK, SIM, JEONG HYUN

Принадлежит:

The present invention relates to a method of fabricating electrical contact materials comprising silver-coated carbon nanotubes, and more specifically, to a method of fabricating electrical contact materials comprising silver-coated carbon nanotubes, the method comprising the steps of: (a) placing carbon nanotubes in a nitric acid solution and performing ultrasonic dispersion and acid treatment; (b) washing the carbon nanotubes treated with the ultrasonic dispersion and the acid treatment in the step (a); (c) mixing sequentially, the washed carbon nanotubes with a mixture of tin chloride and hydrochloric acid, and with a mixture of palladium chloride and hydrochloric acid, and then applying ultrasonic waves thereto to bind tin and palladium to the surface of the carbon nanotubes; (d) adding a silver nitrate aqueous solution and a sodium chloride aqueous solution, and mixing until the color becomes clear, and then mixing with the carbon nanotubes produced in the step (c); (e) mixing with ...

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Номер записи: 31

17-10-2019 дата публикации

METHOD FOR SCREENING MATERIAL SUPPRESSING FINE DUST-INDUCED RETINAL CELL DAMAGE AND COMPOSITION FOR SUPPRESSING FINE DUST-INDUCED RETINAL CELL DAMAGE

Номер: WO2019199088A1

Автор: CHOI, Hyun Jung, KIM, Hyoung June, LEE, Tae Ryong, CHO, Dong Hyung, BAE, Ji Eun

Принадлежит:

The present invention relates to a method for screening a material suppressing fine dust-induced retinal cell damage, the method comprising a step of identifying a relative degree of formation of primary cilia in retinal cells. According to an aspect of the present invention, a material suppressing fine dust-induced retinal cell damage can be effectively screened and excavated, thereby allowing a plan to develop a business related to eye health associated with fine dust removal.

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Номер записи: 32

01-03-2018 дата публикации

METHOD FOR SCREENING SKIN-WHITENING MATERIAL CONTROLLING PRIMARY CILIA

Номер: WO2018038471A1

Автор: CHOI, Hyun Jung, BAE, Il Hong, KIM, Hyoung June, LEE, Young Jin, LEE, Tae Ryong, CHO, Dong-Hyung, SHIN, Ji Hyun

Принадлежит:

One aspect of the present invention relates to a method for screening a material having a skin-whitening effect, comprising a step of confirming the level of relative formation of primary cilia of melanocytes. Through the one aspect of the present invention, effective screening and discovery of the skin-whitening material can be achieved, thereby promoting significant development of skin whitening-related industries.

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Номер записи: 33

02-06-2016 дата публикации

MELANIN CELL LINE SUBCULTURE SYSTEM AND METHOD FOR DETERMINING DEGREE OF SENESCENCE, PROVIDING COSMETIC INFORMATION, OR SCREENING USING SAME

Номер: WO2016085304A1

Автор: LEE, Eun Kyung, GOH, Myeong Jin, CHOI, Hyun Jung, CHO, Eun Gyung, LEE, Tae Ryong

Принадлежит:

The present description discloses a novel melanin cell line subculture system. Provided is a subculture system comprising subcultured prophase melanin cells and anaphase melanin cells. As such, the subculture system provides an in vitro environment similar to an in vivo environment, and thus is useful for determining the degree of senescence, providing cosmetic information, and screening cell rejuvenation-inducing substances.

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Номер записи: 34

04-04-2013 дата публикации

MELANOCYTE OR PROGENITOR CELL THEREOF ADAPTED TO KERATINOCYTE, AND PREPARATION METHOD THEREOF

Номер: WO2013048139A1

Автор: CHO, Eun Gyung, BIN, Bum Ho, LEE, Tae Ryong, HAN, Ji Yeon, CHOI, Hyun Jung

Принадлежит:

The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.

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Номер записи: 35

17-04-2018 дата публикации

마이크로 ＲＮＡ를 포함하는 색소형성유전자 발현조절용 조성물

Номер: KR0101849102B1

Автор: 김규한, 최현정, 이태룡

Принадлежит: (주)아모레퍼시픽

... 본 발명은 서열번호 1의 miRNA 또는 서열번호 2인 안티센스 핵산 분자를 유효성분으로 포함하는 백모방지 및 흑모생성 또는 피부미백효과 조성물을 제공한다. 또한, 본 발명은 시험물질에 대한 색소형성 유전자의 발현 조절 물질을 스크리닝하는 방법으로서, 서열번호 1의 miRNA 또는 서열번호 2인 안티센스 핵산 분자를 세포에 트랜스펙션시키는 단계; 상기 세포에 시험 물질을 처리하는 단계; 및 상기 시험물질이 색소형성 유전자의 발현을 촉진하는지 또는 억제하는지 여부를 확인하는 단계;를 포함하는 것을 특징으로 하는 색소형성 유전자의 발현 조절 물질 스크리닝 방법을 제공한다.

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Номер записи: 36

25-11-2010 дата публикации

METHOD AND SYSTEM FOR EDITING DOCUMENT TO WHICH ADDITIONAL EXPLANATION OR LINK-RELATED METADATA CAN BE FREELY INPUTTED IN COOPERATION WITH INTERNET SEARCH

Номер: KR2010134753A2

Автор: CHOI, Hyun Jung, KIM, Dong Bum, YUN, Sang Jin, KIM, Su Jin, LEE, Mun Hee, LEE, Seok Heui

Принадлежит:

The present invention relates to a document editing method and system, in which when a user edits a web document such as a post on the Internet, the user can make a block around a specific word or sentence and multi-set and manage any related additional explanation, URL in result of the Internet search or a combination thereof so that detailed information on a corresponding block according to the Internet user's choice can easily be provided. In the document editing method according to the present invention, a document editing means is provided, so when the document editing means edits a document, a certain part of the document is inserted into a block and additional explanation or an Internet address is multi-set, stored and managed as the detailed information that is linked to the corresponding block.

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Номер записи: 37

10-10-2018 дата публикации

METHOD FOR COOKING FRIED CHICKEN, FRIED CHICKEN AND ROASTED CHICKEN FOOD CONTAINING SAME

Номер: KR1020180110253A

Автор: KONG, BYUNG CHUN, CHOI, JUNG RYONG, CHOI, HYUN JUNG, JANG, JIN A

Принадлежит:

Provided are a method for cooking a fried chicken, which comprises the following steps: salting a chicken with a salting solution containing beer and lemon and aging the chicken; applying a barbecue sauce to the aged chicken and baking the chicken with fire; and roasting the chicken roasted with the fire without fire, a fried chicken cooked by the method, and a roasted chicken food containing the fried chicken. One embodiment of the present invention is to provide the method for cooking the fried chicken, which makes the meat quality of chicken smooth, eliminates bad taste, bad odor and the like and has excellent flavor to have high preference. COPYRIGHT KIPO 2018 ...

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Номер записи: 38

22-11-2017 дата публикации

혈장내 유리무세포 DNA(cfDNA)를 이용한 상피세포 성장인자 수용체 유전자 돌연변이 검출용 조성물 및 이를 포함하는 키트

Номер: KR0101800366B1

Автор: 신영기, 변보현, 최현정, 최준석, 문영호, 이종흔, 김지은

Принадлежит: 서울대학교산학협력단, 주식회사 젠큐릭스

... 본 발명은 상피세포 성장인자 수용체 유전자 돌연변이 검출용 조성물 및 이를 포함하는 키트에 관한 것으로, 보다 상세하게는 상피세포 성장인자 수용체 유전자 돌연변이 검출용 프라이머 및 프로브 세트 조성물, 상기 조성물을 포함하는 EGFR 유전자 돌연변이 검출용 키트와 본 발명의 조성물 중 일부 프라이머/프로브 세트를 포함하는 EGFR 유전자 돌연변이 검출용 키트에 관한 것이다. 본 발명의 프라이머/프로브 세트는 암 환자 예후의 치료제에 대한 반응성 예측, 진단뿐만 아니라 암의 전이 또는 재발에 대한 예측이 가능하므로 항암치료제의 투여 필요성 판단을 비롯하여 향후 치료의 방향에 대한 단서를 제시하는 목적 및 암의 전이 또는 재발에 대한 모니터링 목적으로 유용하게 사용할 수 있다.

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Номер записи: 39

27-10-2015 дата публикации

Photoalignment polymer, optical film comprising the polymer and method for fabricating the optical film

Номер: KR0101559704B1

Автор: 서동학, 오병호, 채종민, 유치종, 최광호, 박정언, 황다영, 최현정

Принадлежит: 한양대학교 산학협력단

... 광배향성 중합체, 이를 포함하는 광학필름 및 그 제조방법을 제공한다. 광배향성 중합체는 광중합 특성을 가지는 작용기와 광이성화 특성을 가지는 작용기를 포함하는 고분자 화합물로서, 다양한 광학필름 및 광학장치에 유용하게 적용 가능하다.

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Номер записи: 40

26-05-2016 дата публикации

LOVE CHAIR

Номер: KR101624554B1

Автор: YOO, JANG HO, YOO, BYONG SEOP, YOO, DA EUN, CHOI, HYUN JUNG

Принадлежит: YOO, JANG HO

Disclosed is a love chair which can be used as an aid for a healthy sexual life. According to the embodiment of the present invention, the love chair includes: a base; a chair installed on one side of the base and controlling an angle, wherein an upper body support unit and a lower body support unit are installed to rotate against each other; a holder installed on the other side of the base to be separated from the chair and installed to be higher than at least the lower body support unit of the chair; and a footrest installed in the lower part of the holder. The chair and the holder are installed to move in a direction of facing each other and a vertical direction to the footrest. COPYRIGHT KIPO 2016 ...

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Номер записи: 41

25-10-2017 дата публикации

신규한 피라졸 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 TrkA 관련 질환의 예방 또는 치료용 약학적 조성물

Номер: KR0101789590B1

Автор: 이광호, 최상운, 최현정, 손유화

Принадлежит: 한국화학연구원

... 본 발명은 신규한 피라졸 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 TrkA 관련 질환의 예방 또는 치료용 약학적 조성물에 관한 것으로, 본 발명에 따른 신규한 피라졸, 이의 광학 이성질체, 또는 이의 약학적으로 허용 가능한 염은, TrkA(Tropomyosin receptor kinase A)에 대하여 효과적인 억제 활성을 나타내어 이로부터 유발되는 질환, 대표적으로 암 및 종양의 치료에 유용한 효과가 있다.

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Номер записи: 42

20-12-2018 дата публикации

N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF CANCER

Номер: WO2018230934A1

Автор: LEE, Kwangho, SHIN, Inji, CHOI, Gildon, CHAE, Chong Hak, CHOE, Hyeon Jeong, JUNG, Myoung Eun, JEON, Byeong Uk, CHO, Byoung Chul, PARK, Chae Won, KIM, Hwan, DUGGIRALA, Krishna Babu

Принадлежит:

The present invention relates to a N2,N4-diphenylpyrimidine-2,4-diamine derivative, a method for preparing same, and a pharmaceutical composition containing same as an active ingredient for the prevention or treatment of cancer. The derivative shows a relatively weak EGFR activity inhibitory effect on wild-type EGFR, high inhibitory ability on EGFR mutation, and high inhibitory ability on even FLT3 or FLT3 mutation, and thus can be favorably used in the treatment of cancer with EGFR mutation or cancer with FLT3 or mutation thereof, and the derivative shows a synergy effect at the time of combinative administration, and thus can be favorably used in the treatment of combinative administration.

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Номер записи: 43

07-09-2012 дата публикации

METHOD FOR CALCULATING A THERMAL PROTECTION FACTOR

Номер: WO2012118284A3

Автор: SON, Eui Dong, KIM, Hyeon Chung, KIM, Ji Hyun, CHOI, Hyun Jung, NAM, Gae Won, LEE, Tae Ryong, CHUNG, Jin Ho, JIN, Seon Pil

Принадлежит:

The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.

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Номер записи: 44

01-06-2015 дата публикации

METHOD FOR SCREENING MATERIALS FOR ALLEVIATING AGE-RELATED SKIN DISEASES

Номер: KR1020150059491A

Автор: SON, EUI DONG, CHOI, HYUN JUNG, KIM, HYOUNG JUNE, CHO, EUN GYUNG, LEE, TAE RYONG, CHUNG, JIN HO, LEE, MIN JUNG, OH, JANG HEE, KANG, SO MIN

Принадлежит:

The present invention relates to a method for screening materials capable of ameliorating, preventing or treating age-related dry skin diseases. A pharmaceutical composition for treating or preventing age-related skin diseases includes osteoglycin protein or a material capable of increasing the amount of osteoglycin protein expression as an active ingredient. COPYRIGHT KIPO 2015 ...

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Номер записи: 45

04-04-2017 дата публикации

PRIMER FOR REMOVING BETA2-MICROGLOBULIN GENE, USING CRISPR/CAS9 SYSTEM

Номер: KR1020170037025A

Автор: SHIN, MYUNG GEUN, CHOI, HYUN JUNG

Принадлежит:

The present invention relates to a method for removing a beta 2-microglobulin gene using a CRISPR/CAS9 system, and a primer used therein. The primer is specifically designed to selectively and correctly remove the beta 2-microglobulin gene only, thereby not affecting a non-target gene and specifically and correctly removing the beta 2-microglobulin gene which is the non-target gene so as to remarkably improve removal efficiency. COPYRIGHT KIPO 2017 ...

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Номер записи: 46

25-11-2010 дата публикации

SEMANTIC SEARCH METHOD AND SYSTEM IN WHICH A PLURALITY OF CLASSIFICATION SYSTEMS ARE LINKED

Номер: KR2010134752A2

Автор: CHOI, Hyun Jung, SHIN, Chang Ho, LEE, You Jin, LEE, Seung Beom, LEE, Min Jung

Принадлежит:

In the semantic search method according to the present invention, a database is created from resources corresponding to various classification categories for various divided classification systems obtained by dividing up, into two or more divisions, a classification system having a plurality of classification categories, and associative relationships between two classification categories are established based on similarity values of a first classification category in a first classification system and a second classification category in a second classification system for various keywords such that, when search results for input keywords are provided, the search results can be provided with the resources belonging to a plurality of classification systems divided up by each classification system or by each classification category based on the associative relationships.

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Номер записи: 47

21-02-2018 дата публикации

METHOD FOR SCREENING SUBSTANCES INCREASING HAIR DARKENING BY REGULATING PRIMARY CILIA

Номер: KR1020180017710A

Автор: CHOI, HYUN JUNG, BAE, IL HONG, KIM, HYOUNG JUNE, LEE, YOUNG JIN, LEE, TAE RYONG, CHO, DONG HYUNG, SHIN, JI HYUN

Принадлежит:

The present invention relates to a method for screening a substance having hair darkening effects or a substance for preventing and treating hypomelanosis comprising the step of confirming relative formation degrees of primary cilia of melanocyte. According to one aspect of the present invention, effective screening and development of a hair darkening substance and a material for preventing and treating hypomelanosis are possible so rapid development of related industries can be promoted. COPYRIGHT KIPO 2018 (AA) Specific substance D 0.25 (BB) Specific substance D 0.5 ...

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Номер записи: 48

13-12-2018 дата публикации

OVERLOAD CONTROL METHOD IN WIRELESS COMMUNICATION SYSTEM AND DEVICE FOR SAME

Номер: WO2018226072A2

Автор: KIM, Taehun, KIM, Jaehyun, RYU, Jinsook, CHOE, Hyunjung

Принадлежит:

Disclosed are an overload control method in a wireless communication system and a device for the same. Specifically, a method by which a base station performs an overload control in a wireless communication system can include: a step of receiving an overload start message from a core network; a step of receiving a first radio resource control (RRC) message including a non-access stratum (NAS) message from user equipment (UE); and a step of transmitting an RRC connection release message, for instructing the release of an RRC connection, to the UE when an instruction for instructing data transmission through a control plane in the first RRC message is included.

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Номер записи: 49

08-03-2012 дата публикации

COSMETIC COMPOSITION FOR IMPROVING SKIN ELASTICITY

Номер: WO2012030138A2

Автор: SON, Eui Dong, MIN, Dae Jin, CHANG, Hui Kyoung, CHOI, Hyun Jung, CHO, Seong A, KIM, Ji Hyun, LEE, Tae Ryong

Принадлежит:

A cosmetic composition for improving skin elasticity is provided which contains an active ingredient in the form of a polymersome in which Phyllanthus urinaria extract and an anti-ageing peptide have been stabilised on the inside. The cosmetic composition of the present invention is efficacious in improving skin wrinkles, restoring skin elasticity and increasing the skin water content, and is effective in improving skin elasticity.

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Номер записи: 50

30-11-2017 дата публикации

COMPOSITION FOR DETECTING EPIDERMAL CELL GROWTH FACTOR RECEPTOR GENE MUTATION, AND KIT COMPRISING SAME

Номер: WO2017204577A1

Автор: SHIN, Young Kee, BYUN, Bo Hyun, CHOI, Hyunjeung, CHOI, Joon Seok, MOON, Young Ho, LEE, Jong Heun, CHO,Sang Rea, KIM, Jee Eun, KIM, Myungsun

Принадлежит:

The present invention relates to a composition for detecting an epidermal cell growth factor receptor gene mutation and to a kit comprising the composition and, more specifically, to a primer and probe set composition for detecting an epidermal cell growth factor gene mutation, and to a kit for detecting an EGFR gene mutation, comprising the composition. A method according to the present invention can not only predict and diagnose responsiveness to a therapeutic agent for the prognosis of a cancer patient, but also predict a cancer metastasis or relapse. Thus, the method can be useful for the purposes of determining the need to administer an anticancer therapeutic agent and guiding the direction of future treatment, and for monitoring a cancer metastasis or relapse.

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Номер записи: 51

08-06-2015 дата публикации

ASSEMBLY GABION WALL USING GABION

Номер: KR1020150062870A

Автор: CHOI, HYEON JEONG

Принадлежит:

The present invention relates to a gabion wall which fixates a gabion composed by storing a filling material such as stone, gravel, or the like therein on an outer side to be installed and, more specifically, to an assembly gabion wall using a gabion. A plurality of support frame is fixedly installed in an outer side of a building wall member or a concrete structure. An insertion groove is formed at a consistent distance to a vertical direction to the ground in the support frame. A gabion wherein a filling material is stored is inserted into the insertion groove for an outer wall to be formed. Thus, a wall member in the outside or a concrete structure, and a frame supporting the same are prevented from being intactly exposed. Moreover, harmony with nature is realized as well as providing beauty to more improve utilization. Further, the present invention can be usefully applied to a steel-frame structure or the like without having a concrete structure to be helpfully utilized in wall construction ...

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Номер записи: 52

08-10-2018 дата публикации

피부 색소 침착 조절물질을 스크리닝하는 방법

Номер: KR0101904918B1

Автор: 최현정, 최현, 한지연, 박주열, 신동욱, 이태룡, 노민수, 김광미

Принадлежит: (주)아모레퍼시픽

... 본 발명은 피부 색소 침착 조절물질을 스크리닝하는 방법에 관한 것이다. 본 명세서에 기재된 기술을 이용하면, 피부에 유용한 피부 색소 침착 조절용 물질을 스크리닝할 수 있다. 또한, 본 발명의 세포 간, 세포 내 신호전달 인자 및 전사 인자를 조절함으로써, 피부 멜라닌 양의 감소 또는 증가에 의하여 발생하는 저색소증 또는 과색소침착증 등의 질환을 효과적으로 개선할 수 있다. 즉, 자외선에 의한 피부 흑화 뿐만 아니라, 아토피나 건선에 의한 2차적인 피부 저색소증 및 색소이상증, 피부 염증이 관여한다고 알려져 있는 기미, 점(nevi), 흑자, 검버섯과 같은 피부 과색소침착증, 백반증 또는 백모와 같은 색소 결여증에 유용한 물질을 스크리닝할 수 있고 그 스크리닝 된 물질을 사용하여 상기 증상들을 개선, 치료할 수 있다.

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Номер записи: 53

12-07-2016 дата публикации

CHISEL FOR BREAKER AND MANUFACTURING METHOD THEREOF

Номер: KR101638945B1

Автор: YOO, JANG HO, YOO, BYONG SEOP, YOO, DA EUN, CHOI, HYUN JUNG

Принадлежит: YOO, JANG HO

Disclosed are a chisel for a breaker and a manufacturing method thereof. The chisel for a breaker, according to an embodiment of the present invention, comprises: a mounting part which is installed in a breaker body; and a work part which has a sharp striking part on the front end, wherein the work part comprises: a center part which has relatively high hardness by hardening heat treatment; and an edge part which has lower hardness than the center part by soft nitriding heat treatment. Therefore, the present invention maintains striking performance even if the chisel is used for a long time. COPYRIGHT KIPO 2016 ...

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Номер записи: 54

03-05-2018 дата публикации

COSMETIC CONTAINER

Номер: WO2018080282A1

Автор: LI, Yan, CHOI, Sun Kyung, KIM, Eun Jeong, KIM, Hyun Hee, CHOI, Hyun Jung

Принадлежит:

One embodiment of the present invention can provide a cosmetic container comprising: a main body for accommodating a first solution and a second solution in a single storage space, the first solution and the second solution having different densities from each other and being separated into an original state from the density difference in a mixed state with each other; a first applicator which is provided at one side of the main body and is capable of applying the first solution or a mixed solution of the first solution and the second solution; a second applicator which is provided on the other side of the main body and is capable of applying the second solution; and a selective permeable membrane which is provided in the inside of the main body, is capable of blocking the first solution from moving to the second applicator side, and allows the second solution to pass therethrough.

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Номер записи: 55

07-03-2018 дата публикации

METHOD FOR SCREENING SKIN-WHITENING SUBSTANCES FOR REGULATING PRIMARY CILIA FORMATION

Номер: KR1020180023362A

Автор: CHOI, HYUN JUNG, BAE, IL HONG, KIM, HYOUNG JUNE, LEE, YOUNG JIN, LEE, TAE RYONG, CHO, DONG HYUNG, SHIN, JI HYUN

Принадлежит:

In one aspect, the present invention relates to a method for screening skin-whitening substances, which comprises a step for identifying relative formation degree of primary cilia of melanocytes, and in accordance with one aspect of the present invention, effective screening and excavation of the skin whitening substances are possible, and thus the skin whitening-related industry can be dramatically developed. COPYRIGHT KIPO 2018 (AA) Specific substance D 0.25 (BB) Specific substance D 0.5 ...

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Номер записи: 56

25-04-2013 дата публикации

SYSTEM FOR SCREENING SKIN-WHITENING MATERIAL

Номер: WO2013058578A3

Автор: LEE, Ai Young, LEE, Tae Ryong, CHOI, Hyun Jung

Принадлежит:

Disclosed are a system for screening a skin-whitening material comprising one or more layers which include one or more cells of fibroblasts, keratinocytes, and melanocytes, and a method for screening a skin-whitening material using the system. In addition, the invention presents a composition for skin whitening which comprises a material screened by the method for screening a skin- whitening material as an active ingredient.

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Номер записи: 57

01-03-2018 дата публикации

SKIN-WHITENING COMPOSITION CONTAINING 3-CHLORO-N-[TRANS-4-(METHYLAMINO)CYCLOHEXYL]-N-[[3-(4-PYRIDINYL)PHENYL]METHYL]BENZO[B]THIOPHENE-2-CARBOXAMIDE

Номер: WO2018038465A1

Автор: CHOI, Hyun Jung, BAE, Il Hong, KIM, Hyoung June, LEE, Young Jin, LEE, Tae Ryong, CHO, Dong-Hyung

Принадлежит:

One aspect of the present invention relates to a skin-whitening composition containing, as an active ingredient, 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide, optical or stereoscopic isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof. Through the one aspect of the present invention, a novel whitening material can be provided to consumers and development of skin whitening-related industries can be promoted.

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Номер записи: 58

04-03-2010 дата публикации

OBJECT RECOGNITION SYSTEM, WIRELESS INTERNET SYSTEM HAVING SAME, AND OBJECT-BASED WIRELESS COMMUNICATION SERVICE METHOD USING SAME

Номер: KR2010024584A2

Автор: SHIN, Eui Hyun, CHOI, Hyun Jeong, PARK, Sung Yong

Принадлежит:

An object recognition system includes a virtual object database and a virtual target object determination part. In the virtual object database are stored a plurality of virtual objects consisting of an attribute data set and a service data set. The virtual target object determination part computes the attribute values of an actual target object upon receiving a transmission of actual object recognition data of a previewed actual target object, and it determines as the target virtual object, that virtual object having attribute values that match the attribute values of the actual target object computed for a plurality of virtual objects stored in the virtual object database. In this way, the object recognition system provides service data related to the previewed actual object. Accordingly, it can provide a wireless communication method that surpasses the concept of the existing Internet and is based on actual objects, can form a simple and intuitive wireless Internet environment, and that ...

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Номер записи: 59

14-09-2017 дата публикации

순환 종양 세포를 이용한 암 환자의 2차 치료용 치료제 반응성 진단 방법

Номер: KR0101778789B1

Автор: 신영기, 오명렬, 최준석, 조상래, 정경숙, 변보현, 김진주, 김성수, 최현정

Принадлежит: 서울대학교산학협력단, 주식회사 젠큐릭스

... 본 발명은 순환 종양 세포를 이용한 암 환자의 2차 치료용 치료제 반응성 진단 방법에 관한 것으로, 보다 상세하게는 암 환자의 유전자 변이 정보 검출을 통한 2차 치료 (second line treatment) 판단을 위한 정보를 제공하기 위하여, 환자의 혈액 시료로부터 CTC를 분리하여 검출하는 여러 단계를 포함하는 치료 반응성 예측치를 산출하는 방법으로 자동화에 적합한 방법에 관한 것이다. 본 발명의 방법은 FFPE 조직 시료를 얻기 어려운 2차 치료 대상의 환자의 혈액을 이용하여 치료 반응성 예측치를 산출하여, 환자의 치료제에 대한 반응성 예측, 진단이 가능하므로 항암치료제의 투여 필요성 판단을 비롯하여 향후 치료의 방향에 대한 단서를 제시하는 목적으로 유용하게 사용할 수 있다.

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Номер записи: 60

24-10-2016 дата публикации

MANUFACTURING METHOD OF CANDLE AND CANDLE MANUFACTURED THEREBY

Номер: KR1020160122500A

Автор: CHOI, HYUN JUNG

Принадлежит:

The present invention relates to a manufacturing method of a candle, and to a candle manufactured thereby. More particularly, the manufacturing method of a candle comprises the following steps of: preparing a soy wax; liquefying the soy wax by heating the same; forming a candle main body having a wick by using a mold and the liquefied soy wax; injecting a coagulation retarder to the liquefied soy wax, and mixing the resultant product; injecting the liquefied soy wax mixture to an extrusion device, forming a three-dimensional decorative part with soy wax while squeezing the liquefied soy wax mixture, and stacking the resultant product on top of the candle main body. COPYRIGHT KIPO 2016 ...

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Номер записи: 61

04-04-2017 дата публикации

PRIMER FOR REMOVING PROHIBITIN-2 GENE USING CRISPR/CAS9 SYSTEM

Номер: KR1020170037028A

Автор: SHIN, MYUNG GEUN, CHOI, HYUN JUNG

Принадлежит:

In the present invention, a method for removing a prohibitin-2 gene using a CRISPR/CAS9 system, and a primer used therefor are specially designed to accurately remove the prohibitin-2 gene only, so as to specifically and accurately remove the prohibitin-2 gene only, which is a targeted gene, while having no effect on a non-targeted gene, thereby remarkably improving removal efficiency. COPYRIGHT KIPO 2017 ...

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Номер записи: 62

08-03-2018 дата публикации

COMPOSITION FOR PROMOTING MELANIN CONTAINING 2,4-DICHLORO-A-(3,4-DIRYDRO-4-OXO-2(1H)-QUINAZOLINYLIDENE)-Β-OXO- BENZENEPROPANENITRILE

Номер: WO2018044029A1

Автор: CHOI, Hyun Jung, BAE, Il Hong, KIM, Hyoung June, LEE, Young Jin, LEE, Tae Ryong, CHO, Dong-Hyung

Принадлежит:

One aspect of the present invention relates to a composition containing, as an active ingredient, 2,4-dichloro-a-(3,4-dirydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo- benzenepropanenitrile, optical or stereoscopic isomers thereof, pharmaceutically acceptable salts thereof, hydrates thereof, or solvates thereof, for darkening hair color, preventing hair discoloration, and the prevention and treatment of melanin-reducing disease. According to the one aspect of the present invention, a novel use and effect of the 2,4-dichloro-a-(3,4-dirydro-4-oxo-2(1H)-quinazolinylidene)-β-oxo- benzenepropanenitrile can be provided to consumers and related industries can be promoted.

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Номер записи: 63

21-12-2018 дата публикации

N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER CONTAINING SAME AS EFFECTIVE COMPONENT

Номер: KR1020180135781A

Автор: LEE KWANGHO, SHIN INJI, CHOI GILDON, CHAE CHONG HAK, CHOE HYEON JEONG, JUNG MYOUNG EUN, JEON BYEONG UK, CHO BYOUNG CHUL, PARK CHAE WON, KIM HWAN, KRISHNA BA

Принадлежит:

The present invention relates to a N2,N4-diphenylpyrimidine-2,4-diamine derivative, a preparation method thereof, and a pharmaceutical composition for preventing or treating cancer containing the same as an effective component. The N2,N4-diphenylpyrimidine-2,4-diamine derivative according to the present invention exhibits a high inhibitory effect on EGFR mutation while exhibiting a relatively weak inhibitory effect on EGFR activity against wild-type EGFR, thereby being useful for the treatment of cancer with EGFR mutation. COPYRIGHT KIPO 2019 ...

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Номер записи: 64

02-03-2017 дата публикации

AIR SUPPLY SYSTEM

Номер: KR1020170022422A

Автор: YOO, JANG HO, YOO, BYONG SEOP, YOO, DA EUN, CHOI, HYUN JUNG

Принадлежит:

Disclosed is an air supply system. More specifically, provided is an air supply system which allows people in an evacuation shelter to safely breathe, by supplying air outside a building into the evacuation shelter in the building when an emergency takes place. According to an embodiment of the present invention, the air supply system comprises: an oxygen mask provided in the building; an air duct allowing air outside the building to be drawn into the oxygen mask; a pump provided in the air duct; and a control part supplying air outside the building into the air duct by operating the pump. COPYRIGHT KIPO 2017 ...

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Номер записи: 65

02-06-2016 дата публикации

COMPOSITION FOR INDUCING FACILITATION OF CELL REJUVENATION COMPRISING GENISTEIN OR EPIGALLOCATECHIN GALLATE

Номер: WO2016085302A1

Автор: LEE, Eun Kyung, GOH, Myeong Jin, CHOI, Hyun Jung, CHO, Eun Gyung, LEE, Tae Ryong

Принадлежит:

The present description discloses a novel use of genistein and epigallocatechin gallate (EGCG), a derivative thereof, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, and a solvate thereof. A composition comprising genistein and EGCG, a derivative thereof, an isomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, a hydrate thereof, or a solvate thereof reduces the expression of a factor related to the increase of a melanin pigment forming ability, reduces the expression of a senescence marker protein, and adjusts the expression of an enzyme related to the formation of melanin pigments, and thus may have an effect of rejuvenating cells including melanin cells.

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Номер записи: 66

14-12-2017 дата публикации

질소 함유 다공성 2차원 고분자 담지체를 이용한 금속 촉매 및 이의 제조방법

Номер: KR0101807631B1

Автор: 백종범, 최현정, 자비드 마흐무드

Принадлежит: 울산과학기술원

... 본 발명은 헥사케토사이클로헥산 옥타하이드레이트(hexaketocyclohexane (HKH) octahydrate) 단량체 및 헥사아미노벤젠 트리하이드로클로라이드 (hexaaminobenzene(HAB) trihydrochloride) 단량체를 포함하는 혼합물로부터 제조된 물질, 및 금속 원자를 포함하는 촉매 복합체에 관한 것이다. 본 발명에 따르면 저가 금속을 사용하였음에도 불구하고 기존의 백금촉매를 대체할 수 있을 정도로 촉매 효율 및 촉매 안정성이 우수함이 확인되었다. 뿐만 아니라 용액 공정을 통하여 제조됨으로써 대량생산이 가능하고, 다양한 종류의 금속을 활용함으로써 다양한 용도로 응용이 가능하며 제조 비용이 저렴하여 상업화 가능성이 높음이 확인되었다.

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Номер записи: 67

19-09-2017 дата публикации

파이토크롬을 함유하는 메이크업 화장료 조성물

Номер: KR0101776073B1

Автор: 이화영, 고승용, 황정선, 정지혜, 이지영, 김세진, 최현정

Принадлежит: (주)아모레퍼시픽

... 본 발명은 파이토크롬을 유효성분으로 함유하는 메이크업 화장료 조성물에 관한 것으로, 보다 상세하게는 파이토크롬을 유효성분으로 함유하여 외관 색상이 선명하고 자연스러운 메이크업이 가능하고, 오메가 3,6,9 오일을 더 함유하면 보습 지속 효과를 향상시킬 수 있는 메이크업 화장료 조성물에 관한 것이다.

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Номер записи: 68

27-12-2012 дата публикации

COMPOSITION FOR CONTROLLING CHROMOGENESIS INCLUDING MICRORNA

Номер: WO2012177008A2

Автор: KIM, Kyu Han, CHOI, Hyun Jung, BIN, Bum Ho, LEE, Tae Ryong

Принадлежит:

The present invention relates to a composition for a whitening effect or for the prevention of gray hair, which comprises antisense nucleic acid molecules of sequence number 2, wherein the composition has an miRNA of sequence number 1 or a base sequence complementary to the miRNA of sequence number 1 and can be hybridized to the miRNA. The present invention further relates to a method for not only controlling chromogenesis in test materials but also for screening for expression control materials of chromogenic genes, the method comprising the steps of: transfecting, to a cell, the miRNA of sequence number 1 or the antisense nucleic acid molecules of sequence number 2; treating the test materials in the cell; confirming whether or not the test materials inhibit or promote the expression of the chromogenic genes; and confirming whether or not the color of the cell is changed. The composition and the screening method, according to the present invention, can be used for the whitening effect ...

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Номер записи: 69

11-01-2019 дата публикации

ＡＲＰ１０１을 포함하는 피부 미백용 조성물

Номер: KR0101936689B1

Автор: 장희경, 최현정, 백석윤

Принадлежит: (주)아모레퍼시픽

... 본 발명은 ARP101을 포함하는 피부 미백용 조성물에 관한 것이다. 본 발명의 일 관점인 피부 미백용 조성물은 멜라닌 생성 관련 단백질의 발현을 감소시킴에 따라 멜라닌의 양을 감소시켜서 미백효과를 가질 뿐 아니라 세포 독성이 없어서 유용하다.

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Номер записи: 70

21-05-2018 дата публикации

3차원 매트릭스

Номер: KR0101859500B1

Автор: 최현정, 한지연, 김광미, 노민수, 이태룡

Принадлежит: (주)아모레퍼시픽

... 본 발명은 콜라겐 4, 라미닌, 니도젠 및 프로테오글라이칸을 포함하는 3차원 매트릭스용 조성물 및 상기 조성물을 이용하여 제조한 3차원 매트릭스를 개시한다. 또한 본 발명은 상기 3차원 매트릭스를 이용하여 세포를 배양하는 방법을 개시한다.

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Номер записи: 71

18-08-2017 дата публикации

COMPOSITION CONTAINING MICRORNA

Номер: KR1020170094526A

Автор: KIM, KYU HAN, LEE, TAE RYONG, SHIN, DONG WOOK, SHIM, JOONG HYUN, CHOI, HYUN JUNG

Принадлежит:

MiRNA of sequence number 1 of the present invention is a mimic of has-miR-1248, and can be used as a promotor of the expression of has-miR-1248 to provide skin-whitening effect by suppressing the expressions of pigmentation-related genes, tyrosinase, tyrosinase-related protein-1, and melan-A, whereas miRNA of sequence number 2 is an antisense nucleic acid molecule to the miRNA of the sequence number 1, and can be used as an inhibitor of the expression of has-miR-1248 to provide effects of preventing the graying of hair or growing black hair by promoting the expressions of pigmentation-related genes, tyrosinase, tyrosinase-related protein-1, and melan-A. Additionally, the miRNA of the sequence number 1 can be used as a promotor of the expression of has-miR-1248 to provide excellent regenerative effect on hypodermal cells by suppressing the expressions of hypodermal cell regeneration regulatory genes, tropomyosin 3 and aggrecan. COPYRIGHT KIPO 2017 (AA) Relative TYR/GAPDH mRNA expression ...

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Номер записи: 72

24-10-2017 дата публикации

NOVEL PYRAZOLE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING TRKA-RELATED DISEASES CONTAINING SAME AS ACTIVE INGREDIENT

Номер: KR1020170117704A

Автор: LEE KWANGHO, CHOI, SANG UN, CHOE, HYEON JEONG, SON, YOU HWA

Принадлежит:

The present invention relates to novel pyrazole derivatives, a preparation method thereof and a pharmaceutical composition for preventing or treating tropomyosin receptor kinase A (TrkA)-related diseases containing the same as an active ingredient. According to the present invention, novel pyrazole, optical isomers thereof or pharmaceutically allowable salts thereof show effective inhibitory activities with respect to TrkA, thereby being effective in treating diseases induced from the same, representatively cancer and tumor. COPYRIGHT KIPO 2017 (AA) Proliferation rate (%) (BB) Example 1 ...

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Номер записи: 73

08-03-2018 дата публикации

COMPOSITION CONTAINING SPECIFIC SIRNA FOR PROMOTING MELANIN

Номер: WO2018044028A1

Автор: CHOI, Hyun Jung, BAE, Il Hong, KIM, Hyoung June, LEE, Young Jin, LEE, Tae Ryong, CHO, Dong-Hyung

Принадлежит:

One aspect of the present invention relates to a composition containing, as an active ingredient, siRNA comprising a base sequence according to SEQ ID NO: 1 or SEQ ID NO: 2, for darkening hair color, preventing hair discoloration, and the prevention and treatment of melanin-reducing diseases. According to the one aspect of the present invention, hair-related industries can be promoted and the well-being of relevant consumers can be improved.

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Номер записи: 74

12-10-2017 дата публикации

피부 탄력 개선용 화장료 조성물

Номер: KR0101784940B1

Автор: 손의동, 민대진, 장희경, 최현정, 조성아, 김지현, 이태룡

Принадлежит: (주)아모레퍼시픽

... 여우구슬(Phyllanthusurinaria) 추출물 및 항노화 펩타이드가 내부에 안정화된 폴리머좀(polymersome)을 유효성분으로 함유하는 피부 탄력 개선용 화장료 조성물을 제공한다. 본 발명의 화장료 조성물은 피부 주름 개선, 피부 탄력성 회복 및 피부 수분 함유량 증대 효능을 포함하여 피부 탄력을 개선하는 효과가 있다.

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Номер записи: 75

22-02-2017 дата публикации

ELECTRONIC DEVICE AND METHOD FOR MOVING IMAGE PLAYBACK

Номер: KR1020170019819A

Автор: SOHN, JAE SIK, LEE, YONG GU, CHOI, HYUN JUNG, SARVESH SANT, CHO, JEONG HEUI, PARK, JI YOON, LEE, JUNG EUN

Принадлежит:

The present invention relates to an electronic device and a method for moving image playback. The electronic device according to various embodiments includes: a display; a processor electrically connected to the display; and a memory electrically connected to the processor. The memory stores instructions which are executed so that the processor provides a user interface including first and second regions on the display, plays, in the first region, at least a part of video content stored in the memory at a predetermined rate from a first point of time to a second point of time, and plays, in the second region, the part of the part or more of the video content played back in the first region is played back from the first point of time to the second point of time. Other embodiments are also possible. COPYRIGHT KIPO 2017 (700) Capture moving image (710) Store captured moving image (720) Moving image playback request (730) Play back moving image at first playback rate and output moving image ...

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Номер записи: 76

25-01-2017 дата публикации

COMPOSITION FOR DETECTING EPIDERMAL CELL GROWTH FACTOR RECEPTOR GENE MUTATION BY USING DISASSOCIATED ACELLULAR DNA(cfDNA) IN PLASMA, AND KIT INCLUDING SAME

Номер: KR1020170009603A

Автор: SHIN, YOUNG KEE, BYUN, BO HYUN, CHOI, HYUN JUNG, CHOI, JOON SEOK, MOON, YOUNG HO, LEE, JONG HEUN, KIM, JEE EUN

Принадлежит:

The present invention relates to a composition for detecting an epidermal cell growth factor receptor gene mutation, and to a kit including the same. More specifically, the present invention relates to a primer and probe set composition for detecting an epidermal cell growth factor receptor gene mutation; an EGFR gene mutation detecting kit including the composition; and an EGFR gene mutation detecting kit including a partial primer/probe set of the composition of the present invention. A primer/probe set of the present invention can predict and diagnose the reactivity of a cancer patient with respect to a treating agent, and can also predict the metastasis or reoccurrence of cancer, thereby being able to be useful in determining a necessity of the administration of a cancer treating agent, in providing a clue with respect to a direction of future treatment, and in monitoring the metastasis or reoccurrence of cancer. COPYRIGHT KIPO 2017 ...

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Номер записи: 77

09-03-2018 дата публикации

MELANIN-ENHANCING COMPOSITION COMPRISING 2,4-DICHLORO-A-(3,4-DIHYDRO-4-OXO-2(1H)-QUINAZOLINYLIDENE)-β-OXO-BENZENEPROPANENITRILE

Номер: KR1020180025700A

Автор: CHOI, HYUN JUNG, BAE, IL HONG, KIM, HYOUNG JUNE, LEE, YOUNG JIN, LEE, TAE RYONG, CHO, DONG HYUNG

Принадлежит:

In one aspect, the present invention relates to a composition for making hair color black, preventing hair color from being whitened, and preventing and alleviating melanin-reducing diseases, which comprises 2,4-dichloro-a-(3,4-dihydro-4-oxo-2 (1H)-quinazolinylidene)-β-oxo-benzenepropanenitrile, an optical isomer or a stereoisomer thereof, an acceptable salt thereof, a hydrate thereof, or a solvate thereof as an active ingredient, and according to one aspect of the present invention, novel uses and effects of the 2,4-dichloro-a-(3,4-dihydro-4-oxo-2 (1H)-quinazolinylidene)-β-oxo-benzenepropanenitrile can be provided to consumers, and the development of related industries can be promoted. COPYRIGHT KIPO 2018 (AA) Material A 10 (BB) Material A 30 ...

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Номер записи: 78

08-05-2017 дата публикации

CANDLE PREPARING METHOD

Номер: KR1020170048255A

Автор: CHOI, HYUN JUNG

Принадлежит:

The present invention relates to a method for preparing candles with decorative elements. The candle preparing method includes: a step of preparing soy wax in various kinds and colors; a step of liquefying the prepared soy wax by heating after placing the mass separately in tubular containers; a step of whipping by stirring the soy wax to form fine air bubbles therein while the soy wax is solidified; a step of stacking the soy wax, which is yet to be solidified completely, sequentially in a tubular frame body; a step of removing the tubular frame body and using a knife to cut the soy wax in a vertical direction to prepare shaped products; and a step of arranging and fixing wicks on the upper surfaces of the shaped products in a desired manner. According to the present invention, the candle preparing method includes the steps of: preparing soy wax; heating and liquefying the prepared soy wax; shaping the liquefied soy wax in candle bodies with wicks fitted therein using a frame; stirring ...

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Номер записи: 79

02-07-2018 дата публикации

Composition containing microRNA

Номер: KR0101871920B1

Автор: 김규한, 이태룡, 신동욱, 심중현, 최현정

Принадлежит: (주)아모레퍼시픽

... 본 발명의 서열번호 1의 miRNA는 has-miR-1248의 모방체로서, has-miR-1248의 발현에 대한 촉진제로 사용되어 색소형성 유전자인 티로시나아제, 티로시나아제 관련 단백질 1, 멜란-A의 발현을 억제하여 피부 미백효과를 제공할 수 있으며, 서열번호 2의 miRNA는 상기 서열번호 1의 miRNA에 대한 안티센스 핵산 분자로서 has-miR-1248의 발현에 대한 억제제로 사용되어 색소형성 유전자인 티로시나아제, 티로시나아제 관련 단백질 1, 멜란-A의 발현을 촉진시켜 백모 방지 또는 흑모 생성효능을 제공할 수 있다. 또한, 본 발명의 서열번호 1의 miRNA는 has-miR-1248의 발현에 대한 촉진제로 사용되어 진피세포 재생 조절 유전자인 트로포미오신 3과 아그레칸의 발현을 억제하여 우수한 진피세포 재생 효과를 제공할 수 있다.

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Номер записи: 80

21-12-2018 дата публикации

N2,N4-DIPHENYLPYRIMIDINE-2,4-DIAMINE DERIVATIVE, METHOD FOR MANUFACTURING SAME, AND PHARMACEUTICAL COMPOSITION PREVENTING OR TREATING CANCER CONTAINING SAME AS ACTIVE INGREDIENT

Номер: KR1020180135815A

Автор: LEE KWANGHO, SHIN INJI, CHOI GILDON, CHAE CHONG HAK, CHOE HYEON JEONG, JUNG MYOUNG EUN, JEON BYEONG UK, CHO BYOUNG CHUL, PARK CHAE WON, KIM HWAN, DUGGIRALA KRISHNA BABU

Принадлежит:

The present invention relates to a N2,N4-diphenylpyrimidine-2,4-diamine derivative, a method for manufacturing the same, and a pharmaceutical composition for preventing or treating cancer comprising the same as an active ingredient. The derivative exhibits a relatively weak inhibitory effect of EGFR activity against wild-type EGFR, exhibits a high inhibitory effect on EGFR mutation, and exhibits a high inhibitory effect on FLT 2 and mutations of FLT 3. Therefore, the derivative can be useful for the combined-administration treatment of cancer in which EGFR mutation has been induced, cancer in which FLT 3 or mutation thereof has been induced, and exhibits synergetic effects when administered in combination. COPYRIGHT KIPO 2019 (AA) Example 10 30 nM (BB) Example 10 (CC) Example 10+cet.

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Номер записи: 81

25-01-2017 дата публикации

COMPOSITION FOR DETECTING NRAS GENE MUTATION, AND KIT INCLUDING SAME

Номер: KR1020170009605A

Автор: SHIN, YOUNG KEE, BYUN, BO HYUN, CHOI, HYUN JUNG, CHOI, JOON SEOK, MOON, YOUNG HO, LEE, JONG HEUN

Принадлежит:

The present invention relates to a composition for detecting a NRAS gene mutation, and to a kit including the same. More specifically, the present invention relates to a primer and probe set composition for detecting an NRAS gene mutation; an NRAS gene mutation detecting kit including the composition; and an NRAS gene mutation detecting kit including a partial primer/probe set of the composition of the present invention. A primer/probe set of the present invention can predict and diagnose the reactivity of a cancer patient with respect to a treating agent, and can also predict the metastasis or reoccurrence of cancer, thereby being able to be useful in determining a necessity of the administration of a cancer treating agent and in providing a clue with respect to a direction of future treatment. COPYRIGHT KIPO 2017 ...

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Номер записи: 82

15-02-2016 дата публикации

SKIN WHITENING COMPOSITION CONTAINING CHEMOKINE

Номер: KR1020160015745A

Автор: LEE, EUN KYUNG, HAN, JI YEON, CHO, EUN GYUNG, LEE, TAE RYONG, CHOI, HYUN JUNG

Принадлежит:

The present invention relates to a composition which contains chemokine, especially an interferon-inducible T-cell alpha chemoattractant (ITAC). In addition, the composition of the present invention decreases the genetic expression of factors associated with the production of melanic pigments in melanocytes, thereby exhibiting skin whitening effects as well, wherein the content of the ITAC is 0.0001-0.0005 wt% with respect to the total weight of the composition. COPYRIGHT KIPO 2016 (AA) Relative expression amount of TYR mRNA/GAPDH (BB) Relative expression amount of MITF mRNA/GAPDH (CC) Relative expression amount of TRP1 mRNA/GAPDH (DD) Relative expression amount of DCT mRNA/GAPDH (EE) Relative expression amount of MART1 mRNA/GAPDH (FF) Relative expression amount of gp100 mRNA/GAPDH (G1,G2,G3,G4,G5,G6) Untreated control group ...

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Номер записи: 83

07-06-2017 дата публикации

METAL CATALYST USING TWO-DIMENSIONAL, NITROGEN-CONTAINING, AND POROUS POLYMER CARRIER AND PREPARING METHOD THEREOF

Номер: KR1020170062221A

Автор: BAEK, JONG BEOM, CHOI, HYUN JUNG, JAVEED MAHMOOD

Принадлежит:

The present invention relates to a catalyst complex including metal atoms and a substance prepared with a mixture of hexaketocyclohexane (HKH) octahydrate monomers and hexaaminobenzene (HAB) trihydrochloride monomers. According to the present invention, the catalyst complex has excellent catalyst efficiency and stability sufficiently for replacing a conventional platinum catalyst despite using low-cost metal materials. The catalyst complex enables mass production by being prepared through a solution process and utilizes various metal materials to be utilized for various purposes while reducing the production cost and enhancing the commercialization possibility. COPYRIGHT KIPO 2017 ...

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Номер записи: 84

16-03-2023 дата публикации

무선 통신 시스템에서 네트워크 슬라이스를 고려한 셀 선택 또는 셀 재선택을 위한 방법 및 장치

Номер: KR20230037571A

Автор: 최현정, 이승준, 정성훈, 김상원, 김홍석

Принадлежит:

... 무선 통신 시스템에서 네트워크 슬라이스를 고려한 셀 선택 또는 셀 재선택 방법 및 장치가 설명된다. 무선 장치는 복수의 네트워크 슬라이스를 설정한다. 무선 장치는 상기 복수의 네트워크 슬라이스와 관련된 네트워크 슬라이스 정보를 수신한다. 무선 장치는 특정 서비스에 대한 PDU 세션을 수립한다. 무선 장치는 주파수 정보에 기초하여, 상기 복수의 네트워크 슬라이스 중, 상기 PDU 세션에 의해 사용되는, 상기 적어도 하나의 네트워크 슬라이스를 지원하는 하나 이상의 주파수를 결정한다. 무선 장치는 상기 결정된 하나 이상의 주파수에 기초하여 셀 선택 절차 및/또는 셀 재선택 절차를 수행한다.

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Номер записи: 85

25-11-2010 дата публикации

METHOD AND SYSTEM FOR EDITING DOCUMENT TO WHICH ADDITIONAL EXPLANATION OR LINK-RELATED METADATA CAN BE FREELY INPUTTED IN COOPERATION WITH INTERNET SEARCH

Номер: WO2010134753A3

Автор: CHOI, Hyun Jung, KIM, Dong Bum, YUN, Sang Jin, KIM, Su Jin, LEE, Mun Hee, LEE, Seok Heui

Принадлежит:

The present invention relates to a document editing method and system, in which when a user edits a web document such as a post on the Internet, the user can make a block around a specific word or sentence and multi-set and manage any related additional explanation, URL in result of the Internet search or a combination thereof so that detailed information on a corresponding block according to the Internet user's choice can easily be provided. In the document editing method according to the present invention, a document editing means is provided, so when the document editing means edits a document, a certain part of the document is inserted into a block and additional explanation or an Internet address is multi-set, stored and managed as the detailed information that is linked to the corresponding block.

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Номер записи: 86

06-03-2018 дата публикации

SKIN-WHITENING COMPOSITION CONTAINING CYTOCHALASIN D

Номер: KR1020180022416A

Автор: CHOI, HYUN JUNG, BAE, IL HONG, KIM, HYOUNG JUNE, LEE, YOUNG JIN, LEE, TAE RYONG, CHO, DONG HYUNG, SHIN, JI HYUN, SHIN, DONG WOON

Принадлежит:

According to one aspect of the present invention, the present invention relates to a skin-whitening composition containing cytochalasin D, an optical isomer or a stereoisomer thereof, an acceptable salt thereof, a hydrate thereof, or a solvate thereof as an active ingredient. According to one aspect of the present invention, the skin-whitening composition can provide consumers with novel skin-whitening substances, thereby developing industries associated with skin-whitening. COPYRIGHT KIPO 2018 ...

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Номер записи: 87

23-10-2015 дата публикации

a bench

Номер: KR0101562880B1

Автор: 최현정

Принадлежит: 최현정

... 본 발명은 인체의 둔부와 대퇴부를 지지하면서 앉아서 휴식을 취할 수 있도록 하는 평벤치(Bench)에 관한 것으로, 더욱 상세하게는 지면에 수직하게 일정한 간격으로 다수개의 세로지주대를 설치 고정하고, 상기 세로지주대에는 인체의 둔부와 대퇴부가 지지될 수 있도록 하는 상판프레임을 설치하고 상기 세로지주대에는 돌이나 석재 등의 채움재가 채워진 돌망태를 사면으로 삽설하여 구성함으로써, 돌망태의 시공을 간단하게 할 수 있으면서 벤치와 자연환경을 조화시킬 수 있도록 하여 심미감을 돋보이게 하여 그 효용성을 한층 높이도록 하는 돌망태를 이용한 평벤치에 관한 것이다.

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Номер записи: 88

06-03-2018 дата публикации

SKIN-WHITENING COMPOSITION CONTAINING 3-CHLORO-N-[TRANS-4-(METHYLAMINO)CYCLOHEXYL]-N-[[3-(4-PYRIDINYL)PHENYL]METHYL]BENZO[B]THIOPHENE-2-CARBOXAMIDE

Номер: KR1020180022439A

Автор: CHOI, HYUN JUNG, BAE, IL HONG, KIM, HYOUNG JUNE, LEE, YOUNG JIN, LEE, TAE RYONG, CHO, DONG HYUNG

Принадлежит:

According to one aspect of the present invention, the present invention relates to a skin-whitening composition containing 3-chloro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]benzo[b]thiophene-2-carboxamide, an optical or a stereoisomer thereof, an acceptable salt thereof, a hydrate thereof, or a solvate thereof as an active ingredient. According to one aspect of the present invention, it is possible to provide novel skin-whitening materials to consumers, and promote development of skin-whitening-related industries. COPYRIGHT KIPO 2018 ...

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Номер записи: 89

04-03-2010 дата публикации

OBJECT RECOGNITION SYSTEM, WIRELESS INTERNET SYSTEM HAVING SAME, AND OBJECT-BASED WIRELESS COMMUNICATION SERVICE METHOD USING SAME

Номер: KR2010024584A4

Автор: SHIN, Eui Hyun, CHOI, Hyun Jeong, PARK, Sung Yong

Принадлежит:

An object recognition system includes a virtual object database and a virtual target object determination part. In the virtual object database are stored a plurality of virtual objects consisting of an attribute data set and a service data set. The virtual target object determination part computes the attribute values of an actual target object upon receiving a transmission of actual object recognition data of a previewed actual target object, and it determines as the target virtual object, that virtual object having attribute values that match the attribute values of the actual target object computed for a plurality of virtual objects stored in the virtual object database. In this way, the object recognition system provides service data related to the previewed actual object. Accordingly, it can provide a wireless communication method that surpasses the concept of the existing Internet and is based on actual objects, can form a simple and intuitive wireless Internet environment, and that ...

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Номер записи: 90

28-02-2019 дата публикации

OVERLOAD CONTROL METHOD IN WIRELESS COMMUNICATION SYSTEM AND DEVICE FOR SAME

Номер: WO2018226072A3

Автор: KIM, Taehun, KIM, Jaehyun, RYU, Jinsook, CHOE, Hyunjung

Принадлежит:

Disclosed are an overload control method in a wireless communication system and a device for the same. Specifically, a method by which a base station performs an overload control in a wireless communication system can include: a step of receiving an overload start message from a core network; a step of receiving a first radio resource control (RRC) message including a non-access stratum (NAS) message from user equipment (UE); and a step of transmitting an RRC connection release message, for instructing the release of an RRC connection, to the UE when an instruction for instructing data transmission through a control plane in the first RRC message is included.

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Номер записи: 91

25-01-2017 дата публикации

COMPOSITION FOR DETECTING KRAS GENE MUTATION, AND KIT INCLUDING SAME

Номер: KR1020170009604A

Автор: SHIN, YOUNG KEE, BYUN, BO HYUN, CHOI, HYUN JUNG, CHOI, JOON SEOK, MOON, YOUNG HO, LEE, JONG HEUN

Принадлежит:

The present invention relates to a composition for detecting a KRAS gene mutation, and to a kit including the same. More specifically, the present invention relates to a primer and probe set composition for detecting a KRAS gene mutation; a KRAS gene mutation detecting kit including the composition; and a KRAS gene mutation detecting kit including a partial primer/probe set of the composition of the present invention. A primer/probe set of the present invention can predict and diagnose the reactivity of a cancer patient with respect to a treating agent, and can also predict the metastasis or reoccurrence of cancer, thereby being able to be useful in determining a necessity of the administration of a cancer treating agent and in providing a clue with respect to a direction of future treatment. COPYRIGHT KIPO 2017 ...

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Номер записи: 92

07-09-2012 дата публикации

METHOD FOR CALCULATING A THERMAL PROTECTION FACTOR

Номер: WO2012118284A2

Автор: SON, Eui Dong, KIM, Hyeon Chung, KIM, Ji Hyun, CHOI, Hyun Jung, NAM, Gae Won, LEE, Tae Ryong, CHUNG, Jin Ho, JIN, Seon Pil

Принадлежит:

The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.

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Номер записи: 93

23-04-2020 дата публикации

COMPOSITION FOR STRENGTHENING SKIN BARRIER

Номер: WO2020080797A1

Автор: CHOI, Eun Jeong, KIM, Hyoung June, LEE, Tae Ryong, CHOI, Hyunjung

Принадлежит:

Provided is a composition for strengthening the skin barrier, containing, as an active ingredient, a compound represented by a specific chemical formula.

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Номер записи: 94

22-10-2015 дата публикации

SKIN IMPROVING SUBSTANCE REGULATING CADHERIN 11 OR N-CADHERIN EXPRESSION, AND METHOD FOR SCREENING FOR SAME

Номер: WO2015160147A1

Автор: LEE, Ai Young, KIM, Nan Hyung, LEE, Tae Ryong, CHOI, Hyun Jung, LEE, Eun Kyung, CHO, Eun Gyung

Принадлежит:

The present invention can alleviate skin hyperpigmentation and can provide skin whitening effects by providing: a composition for skin improvement, containing, as an active ingredient, a substance inhibiting the expression of cadherin 11 and/or N-cadherin; and a skin improving kit including the same. In addition, the present invention can effectively screen for a skin improving substance by providing a system for screening for a skin improving substance containing a coculture product of at least two among fibroblasts, keratinocytes and melanocytes, and a method for screening for a skin improving substance, comprising the steps of: treating, with a candidate substance, a coculture product of the system for screening for a skin improving substance; and measuring the expression change in cadherin 11 and/or N-cadherin.

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Номер записи: 95

12-10-2018 дата публикации

METHOD FOR DETERMINING QUALITY OF NUCLEIC ACID OF BIOLOGICAL SAMPLE

Номер: KR1020180112727A

Автор: SHIN, YOUNG KEE, KIM, JIN JU, KIM, SUNG SU, CHOI, HYUN JEUNG, MOON, YOUNG HO, KIM, MYUNG SUN, KIM, JEE EUN

Принадлежит:

The present invention relates to a method for determining the DNA quality of a biological sample. More particularly, the present invention relates to a method for determining the DNA quality of a biological sample by performing a quantitative polymerase chain reaction (PCR) using a primer capable of amplifying a target gene, a method for manufacturing a primer used in the method, and a method for standardizing the amount of target gene detected by applying the determined DNA quality. According to the method of the present invention, the DNA quality of a biological sample used for gene analysis can be objectively evaluated, and an objective result on the expression ratio of a gene mutation can be provided. Therefore, the method can be effective in providing reliable information in the field of clinical research and accompanying diagnosis. COPYRIGHT KIPO 2018 ...

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Номер записи: 96

08-06-2016 дата публикации

SUBCULTURE SYSTEM FOR STRAIN OF MELANOCYTE AND METHOD FOR DETERMINING AGING LEVEL, PROVIDING BEAUTY TIPS, OR SCREENING USING SAME

Номер: KR1020160065038A

Автор: LEE, EUN KYUNG, GOH, MYEONG JIN, CHOI, HYUN JUNG, CHO, EUN GYUNG, LEE, TAE RYONG

Принадлежит:

Disclosed is a subculture system for a novel strain of melanocyte. The subculture system includes subcultured melanocytes undergoing a prophase and an anaphase. In addition, the subculture system provides an in vivo-like in vitro condition, thereby being useful for determining the aging level, providing beauty tips, and screening a cell regeneration-inducing substance. COPYRIGHT KIPO 2016 (AA) Comparison of mRNA expression of p16 (BB) Comparison of mRNA expression of p21 ...

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Номер записи: 97

04-06-2020 дата публикации

METHOD AND DEVICE FOR OPERATING IN WIRELESS COMMUNICATION SYSTEM

Номер: WO2020111836A1

Автор: AHM, Joonkui, CHOE, Hyunjung, PARK, Changhwan

Принадлежит:

A method and device for a wireless communication system according to one embodiment of the present invention receive a radio resource control (RRC) connection release message and release an RRC connection on the basis of the RRC connection release message, wherein the RRC connection release message includes information about a target Internet of Things (IoT) mode, and the communication device can be switched from a source IoT mode to the target IoT mode on the basis of the information about the target IoT mode.

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Номер записи: 98

30-04-2020 дата публикации

COMPOSITION FOR ENHANCING SKIN BARRIER

Номер: WO2020085776A1

Автор: CHOI, Eun Jeong, KIM, Hyoung June, LEE, Tae Ryong, CHOI, Hyunjung

Принадлежит:

Provided is a composition for enhancing the skin barrier, comprising a compound represented by a specific chemical formula as an effective component.

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Номер записи: 99

02-03-2017 дата публикации

METHOD FOR DIAGNOSING RESPONSIVENESS OF SECOND LINE TREATMENT FOR CANCER PATIENT USING CIRCULATING TUMOR CELLS

Номер: KR1020170023057A

Автор: SHIN, YOUNG KEE, OH, MYUNG RYURL, CHOI, JOON SEOK, CHO, SANG RAE, CHUNG, KYUNG SOOK, BYUN, BO HYUN, KIM, JIN JU, KIM, SUNG SU, CHOI, HYUN JEUNG

Принадлежит:

The present invention relates to a method for diagnosing a responsiveness of second line treatment for a cancer patient using circulating tumor cells. More specifically, the present invention relates to a suitably automatable method for calculating a predicted value of a treatment responsiveness, wherein the method comprises various steps of separating and detecting CTC from a blood sample of a patient so as to provide information for determining second line treatment through detection of gene mutation information of a cancer patient. The method of the present invention calculates a predicted value of a treatment responsiveness by using the blood of a patient who is an object of secondary treatment and is difficult to obtain an FFPE tissue sample therefrom, so a responsiveness of the patient with respect to a treating agent can be predicted and diagnosed. Thus, a necessity of the administration of an anticancer agent can be determined, and a clue related to a future treatment direction ...

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Номер записи: 100