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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 17. Отображено 17.
11-05-2015 дата публикации

COMPOSITION INCLUDING AUCUBA JAPONICA EXTRACT FOR PREVENTION OR TREATING DIABETIC COMPLICATIONS

Номер: KR1020150050778A
Принадлежит:

The present invention relates to a composition including an Aucuba japonica extract or a fraction thereof as an active ingredient for preventing or treating diabetic complications. More specifically, the present invention relates to a pharmaceutical or food composition including an Aucuba japonica extract or a fraction thereof as an active ingredient for preventing or treating diabetic complications. Moreover, the present invention relates to a method for preventing or treating diabetic complications by using the composition. COPYRIGHT KIPO 2015 (AA) Normal group (BB) Group processed to have high blood sugar (CC) Group treated with a medicine ...

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05-12-2016 дата публикации

Colona auricaulata 추출물을 포함하는 당뇨합병증의 예방 또는 치료용 조성물

Номер: KR0101681980B1
Принадлежит: 한국 한의학 연구원

... 본 발명은 Colonaauricaulata 추출물 또는 이의 분획물을 유효성분으로 포함하는 당뇨합병증 예방 또는 치료용 조성물에 관한 것이다. 구체적으로, 본 발명은 Colonaauricaulata 추출물 또는 이의 분획물을 유효 성분으로 함유하는 당뇨합병증의 예방 또는 치료용 약학적 조성물, 또는 당뇨합병증의 예방 또는 개선용 식품 조성물에 관한 것이다. 또한, 본 발명은 상기 조성물을 이용하여 당뇨합병증을 예방 또는 치료하는 방법에 관한 것이다.

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18-10-2018 дата публикации

COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING POLYCYSTIC OVARY SYNDROME-RELATED DISEASES COMPRISING ECKLONIA CAVA EXTRACT AS ACTIVE INGREDIENT

Номер: WO2018190630A1
Принадлежит:

The present invention relates to a composition for preventing, ameliorating or treating polycystic ovary syndrome-related diseases comprising an Ecklonia cava extract as an active ingredient. The Ecklonia cava extract, which is an active ingredient of the present invention, has an activity of regulating the production of androgen dehydroepiandrosterone (DHEA), an effect of reducing the luteinizing hormone/follicle stimulating hormone ratio in the blood, an effect of increasing follicular stimulating hormone in the blood, and an effect of reducing blood testosterone and the number of ovarian follicular cysts. Therefore, the Ecklonia cava extract can be effectively used for preventing, ameliorating or treating one or more diseases selected from hyperandrogenism, amenorrhea, hypomenorrhea, dysfunctional uterine bleeding, premature menopause, infertility, ovarian failure, and endometriosis, which are polycystic ovary syndrome-related diseases.

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11-05-2015 дата публикации

COMPOSITION INCLUDING COLONA AURICAULATA EXTRACT FOR PREVENTION OR TREATING DIABETIC COMPLICATIONS

Номер: KR1020150050779A
Принадлежит:

The present invention relates to a composition including a Colona auricaulata extract or a fraction thereof as an active ingredient for preventing or treating diabetic complications. More specifically, the present invention relates to a pharmaceutical or food composition including a Colona auricaulata extract or a fraction thereof as an active ingredient for preventing or treating diabetic complications. Moreover, The present invention relates to a method for preventing or treating diabetic complications by using the composition. COPYRIGHT KIPO 2015 ...

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06-12-2016 дата публикации

식나무 추출물을 포함하는 당뇨합병증의 예방 또는 치료용 조성물

Номер: KR0101682697B1
Принадлежит: 한국 한의학 연구원

... 본 발명은 식나무 추출물 또는 이의 분획물을 유효성분으로 포함하는 당뇨합병증 예방 또는 치료용 조성물에 관한 것이다. 구체적으로, 본 발명은 식나무 추출물 또는 이의 분획물을 유효 성분으로 함유하는 당뇨합병증의 예방 또는 치료용 약학적 조성물, 또는 당뇨합병증의 예방 또는 개선용 식품 조성물에 관한 것이다. 또한, 본 발명은 상기 조성물을 이용하여 당뇨합병증을 예방 또는 치료하는 방법에 관한 것이다.

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03-12-2015 дата публикации

PHARMACEUTICAL COMPOSITION CONTAINING EUPHORBIA PEKINENSIS OR REFINED FRACTION THEREOF AS ACTIVE INGREDIENT FOR PREVENTING AND TREATING DIABETIC COMPLICATIONS AND ANGIOEDEMA

Номер: KR1020150135746A
Принадлежит:

An Euphorbia pekinensis extract or a refined fraction thereof of the present invention: inhibits excessive generation of a final glucose oxide; inhibits the final glucose oxide in a human retinal pigment epithelial cell strain; prevents the diameter of a vitreoretinal blood vessel from being extended by high blood pressure in an ophthalmological model of diabetic zebra fish which is an animal model; inhibits damage to blood-retinal barrier breakage (BRB) caused by VEGF; inhibits damage to a blood retinal barrier in a type 2 diabetic model; exhibits an effect of preventing (treating) eye diseases resulting from an effect of preventing damage to occludin, a kind of protein for tightly binding retina; reduces proteinuria; reduces accumulation of 8-OHdG in urine and a kidney; prevents damage to a kidney by preventing accumulation of the final glucose oxide in the kidney; exhibits an effect of inhibiting lower limb edema in an animal varicose vein mode; and thus can be advantageously used as ...

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03-11-2016 дата публикации

천연 혼합 추출물을 유효성분으로 함유하는 당뇨합병증 및 혈관부종 예방 또는 치료용 약학적 조성물

Номер: KR0101671842B1
Принадлежит: 한국 한의학 연구원

... 본 발명의 계지(Cinnamomi Twig) 및 목단피(Moutan Root Bark), 계지 및 작약(Peony Root), 또는 계지 및 적복령(Poria) 혼합 추출물은 만성적 당뇨상태에서 발생하는 과도한 최종당화산물 생성을 억제하고, 최종당화산물과 기질 단백질과의 교차결합 파쇄효능을 나타내며, 고혈당 환경 또는 노화 환경에 처한 사람망막색소상피 세포주에서 최종당화산물 생성억제 효능이 우수하고, 다양한 당뇨합병증 동물모델, 황반변성 동물모델 및 하지부종 동물모델에서 당뇨합병증과 황반변성, 망막부종 및 하지부종을 지연, 예방 및 치료 효능이 우수한 것을 확인함으로써, 상기 혼합 추출물을 당뇨병성 망막증, 당뇨병성 신증, 당뇨병성 신경병증 등을 포함하는 당뇨합병증(diabetic complications) 및 황반(망막)부종, 황반변성 및 하지정맥류를 포함하는 혈관부종(angioedema)의 예방 및 치료용 조성물의 유효성분으로서 유용하게 사용될 수 있다.

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11-04-2017 дата публикации

천연 혼합 추출물을 유효성분으로 함유하는 당뇨합병증 및 혈관부종 예방 또는 치료용 약학적 조성물

Номер: KR0101725912B1
Принадлежит: 한국 한의학 연구원

... 본 발명의 계지(Cinnamomi Twig) 및 목단피(Moutan Root Bark), 계지 및 작약(Peony Root), 또는 계지 및 적복령(Poria) 혼합 추출물은 만성적 당뇨상태에서 발생하는 과도한 최종당화산물 생성을 억제하고, 최종당화산물과 기질 단백질과의 교차결합 파쇄효능을 나타내며, 고혈당 환경 또는 노화 환경에 처한 사람망막색소상피 세포주에서 최종당화산물 생성억제 효능이 우수하고, 다양한 당뇨합병증 동물모델, 황반변성 동물모델 및 하지부종 동물모델에서 당뇨합병증과 황반변성, 망막부종 및 하지부종을 지연, 예방 및 치료 효능이 우수한 것을 확인함으로써, 상기 혼합 추출물을 당뇨병성 망막증, 당뇨병성 신증, 당뇨병성 신경병증 등을 포함하는 당뇨합병증(diabetic complications) 및 황반(망막)부종, 황반변성 및 하지정맥류를 포함하는 혈관부종(angioedema)의 예방 및 치료용 조성물의 유효성분으로서 유용하게 사용될 수 있다.

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07-09-2016 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DIABETIC COMPLICATIONS AND ANGIOEDEMA COMPRISING NATURAL MIXTURE EXTRACTS

Номер: KR1020160105743A
Принадлежит:

A mixed extract of Cinnamomi twig and Moutan root bark, Cinnamomi twig and peony root, or Cinnamomi twig and Poria according to the present invention has been confirmed to inhibit the excessive generation of advanced glycation end products, which occurs under chronic diabetic conditions; exhibit the effect of fragmentizing a cross-link between the advanced glycation end products and matrix proteins; have an excellent effect in inhibiting the generation of the advanced glycation end products in a human retinal pigment epithelial cell line subjected to a hyperglycemic or aging environment; and have excellent effects in delaying, preventing, and treating diabetic complications, macular degeneration, commotio retinae, and lower extremity edema in various animal models of diabetic complications, macular degeneration, and lower extremity edema. Thus, the mixture extract can be beneficially used as an active ingredient in a composition for preventing and treating diabetic complications including ...

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02-12-2015 дата публикации

PHARMACEUTICAL COMPOSITION CONTAINING NATURAL COMPOSITE EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING DIABETIC COMPLICATIONS AND ANGIOEDEMA

Номер: KR1020150135138A
Принадлежит:

A composite extract of Cinnamomi twigs, Moutan root bark, and Cinnamomi twigs and peony roots, or Cinnamomi twigs and peony roots of the present invention: inhibits excessive generation of a final glucose oxide caused in a chronic diabetes state; exhibits an effect of destructing cross-inking between the final glucose oxide and a substrate protein; has an excellent effect of inhibiting generation of the final glucose oxide in a human retinal pigment epithelial cell strain in a high blood sugar or aging environment; is proven to have excellent effects of delaying, preventing, and treating diabetes complications, macular degeneration, retinal edema, and lower limb edema in various a diabetic complication animal model, a macular degeneration animal model, and a lower limb edema animal model; and thus can be advantageously used as an active ingredient of a composition for preventing and treating diabetic complications, including diabetic retinopathy, and diabetic neuropathy, and angioedema ...

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24-11-2015 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ANGIOEDEMA, CONTAINING PEONY ROOTS OR MIXED EXTRACT OF PEONY ROOTS AND LICORICE AS ACTIVE INGREDIENT

Номер: KR101571153B1
Принадлежит: KOREA INSTITUTE OF ORIENTAL MEDICINE

The present invention relates to a pharmaceutical composition for preventing or treating angioedema, containing an extract of peony roots or a mixed extract of peony roots and licorice as an active ingredient. More specifically, the mixed extract of peony roots and licorice of the present invention: suppresses excessive production of an advanced glycation end product which may cause macular degeneration; inhibits the breakdown of a blood-retinal barrier causing commotio retinae in various animal models; protects or treats a subretinal region causing dry macular degeneration; and suppresses angiogenesis. Therefore, the mixed extract of peony roots and licorice can be effectively used as an active ingredient of the composition for preventing or treating angioedema including macular degeneration, macular edema, commotio retinae or varicose veins. COPYRIGHT KIPO 2016 ...

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26-11-2015 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETIC COMPLICATIONS AND ANGIOEDEMA, CONTAINING NATURAL MIXTURE EXTRACT AS ACTIVE INGREDIENT

Номер: WO2015178703A1
Принадлежит:

The extract of a mixture of cinnamon twig and moutan root bark, cinnamon twig and peony root, or cinnamon twig and poria according to the present invention has been confirmed to inhibit the excessive generation of advanced glycation end products, which occurs under chronic diabetic conditions, exhibit the effect of fragmentizing a cross-link between the advanced glycation end products and matrix proteins, have an excellent effect in inhibiting the generation of the advanced glycation end products in a human retinal pigment epithelial cell line subjected to a hyperglycemic or aging environment, and have excellent effects in delaying, preventing, and treating diabetic complications, macular degeneration, commotio retinae, and lower extremity edema in various animal models of diabetic complications, macular degeneration, and lower extremity edema, and thus the mixture extract can be usefully used as an active ingredient for a composition for preventing and treating diabetic complications, ...

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26-11-2015 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING ANGIOEDEMA, CONTAINING EXTRACT OF PEONY ROOT OR MIXTURE OF PEONY ROOT AND LICORICE AS ACTIVE INGREDIENT

Номер: WO2015178702A1
Принадлежит:

The present invention relates to a pharmaceutical composition for preventing or treating angioedema, containing as an active ingredient a peony root extract or an extract of a mixture of peony root and licorice. In particular, the extract of a mixture of peony root and licorice according to the present invention inhibits the excessive generation of advanced glycation end products, which may cause macular degeneration, inhibits blood-retinal barrier breakdown causing commotio retinae in various animal models, protects or treats a subretinal region causing dry macular degeneration, inhibits angiogenesis causing wet macular degeneration, and thus can be usefully used as an active ingredient for the composition for preventing and treating angioedema including macular degeneration, macular edema, commotio retinae, or varicose veins.

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12-10-2018 дата публикации

COMPOSITION COMPRISING ECKLONIA CAVA EXTRACT AS ACTIVE INGREDIENT FOR PREVENTING, RELIEVING OR TREATING DISEASE ASSOCIATED WITH POLYCYSTIC OVARY SYNDROME

Номер: KR101907849B1
Принадлежит: KOREA INSTITUTE OF ORIENTAL MEDICINE

The present invention relates to a composition comprising an Ecklonia cava extract as an active ingredient for preventing, relieving or treating diseases associated with polycystic ovary syndrome wherein the Ecklonia cava extract as an active ingredient of the present invention has an activity of regulating the production of androgen dehydroepiandrosterone (DHEA), has an effect of decreasing the proportion of blood luteinizing hormone/follicular stimulating hormone, an effect of increasing the production of blood follicular stimulating hormone and an effect of decreasing the production of testosterone and follicular cysts. The composition of the present invention can be effectively used for preventing, treating or curing one or more of the diseases related to polycystic ovary syndrome, including hyperandrogenism, amenorrhea, hypomenorrhea, dysfunctional uterine bleeding, premature menopause, infertility, ovarian failure, and endometriosis. COPYRIGHT KIPO 2018 (AA) Ecklonia cava extract ...

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31-10-2019 дата публикации

BONE GROWTH-PROMOTING COMPOSITION COMPRISING ALLIUM FISTULOSUM LINN AS ACTIVE INGREDIENT

Номер: WO2019209061A1
Принадлежит:

The present invention relates to a bone growth-promoting composition comprising an Allium fistulosum Linn extract as an active ingredient. The bone growth-promoting composition comprising an Allium fistulosum Linn extract of the present invention promotes bone growth as well as maintains or enhances bone density by means of longitudinal bone growth and growth plate expansion of a child or an adolescent undergoing growth spurt when administered in the form of a drug or food by the child or the adolescent undergoing growth spurt.

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31-12-2015 дата публикации

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETIC COMPLICATIONS AND ANGIOEDEMA CONTAINING NATURAL MIXTURE EXTRACT AS ACTIVE INGREDIENT

Номер: KR1020150146478A
Принадлежит:

According to the present invention, Cinnamomi Twig and Moutan Root Bark, Cinnamomi Twig and Peony Root, or Cinnamomi Twig and Poria mixture extract controls excessive final saccharization product generation generated in a chronic diabetic state. A cross-linking pulverizing effect with a final saccharization product and a substrate protein is exhibited, and a final saccharization product generation controlling effect is excellent in a human retinal pigment epithelial cell strain in a hyperglycemic environment or aging environment. In animal models with diabetic complications, macular degeneration, and underlying edema, diabetic complications, macular degeneration, commotio retinae, and underlying edema may be excellently alleviated, prevented, and treated. The mixture extract may be usefully used as an active ingredient of a composition for preventing and treating diabetic complications including diabetic retinopathy, diabetic nephropathy, and diabetic neuropathy and angioedema including ...

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05-07-2018 дата публикации

COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING DISORDERS ASSOCIATED WITH POLYCYSTIC OVARY SYNDROME, COMPRISING EXTRACT OF TETRAGONIA TETRAGONOIDES AS EFFECTIVE COMPONENT

Номер: KR101874458B1
Принадлежит: KOREA INSTITUTE OF ORIENTAL MEDICINE

The present invention relates to a composition for preventing, alleviating or treating disorders associated with polycystic ovary syndrome, comprising an extract of Tetragonia tetragonoides as an effective component. In particular, the effective component of the present invention, the extract of Tetragonia tetragonoides shows a regulatory activity of dehydroepiandrosterone (DHEA) production; and shows effects of reducing luteinizing hormone in blood, testosterone in blood, and the number of ovarian follicular cysts in ovaries, and thus can be effectively used in the prevention, alleviation or treatment of one or more disorders associated with polycystic ovary syndrome, selected from hyperandrogenemia, amenorrhea, hypomenorrhea, dysfunctional uterine bleeding, premature menopause, sterility, ovarian failure, and endometriosis. COPYRIGHT KIPO 2018 ...

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