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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 13. Отображено 13.
19-07-2018 дата публикации

STABLE LIQUID FORMULA

Номер: WO2018131893A1
Автор: LEE, Joon Won, SHIN, Yeon Kyeong, KANG, Hye Young, KIM, Kwang Woo, KIM, So Young, KIM, Su Jung, OH, Jun Seok, HAN, Won Yong
Принадлежит:

A stable liquid formula according to the present invention comprises an antibody or an antigen-binding fragment thereof; an acetate buffer; glycine; and a surfactant, without inclusion of one or more of a saccharide, a sugar alcohol, and a metal salt, is stable even at a high content of an antibody and superior in terms of osmolality and viscosity, and can be administered subcutaneously.

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Номер записи: 1
23-01-2020 дата публикации

STABLE LIQUID PHARMACEUTICAL PREPARATION

Номер: WO2020017901A1
Автор: KIM, So Young, SHIN, Yeon Kyeong, KANG, Hye Young, KIM, Kwang Woo, OH, Jun Seok, KIM, Su Jung, LEE, Joon Won, HAN, Won Yong, LEE, Jae Bin, ROH, Ji Won
Принадлежит:

A stable liquid pharmaceutical preparation according to the present invention comprises: an antibody or an antigen-binding fragment thereof; a surfactant; a sugar or a derivative thereof; a buffer; and a stabilizer. The stable liquid pharmaceutical preparation according to the present invention has a low viscosity, even when the included antibody content is high as well as when the antibody content is low, and has excellent long-term storage stability on the basis of having excellent stability under accelerated conditions and harsh conditions.

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Номер записи: 2
03-03-2022 дата публикации

STABLE PHARMACEUTICAL PREPARATION

Номер: WO2022045857A3
Автор: ROH, Ji Won, KIM, Kwang Woo, KIM, Su Jung, SHIN, Yeon Kyeong, HAN, Won Yong, OH, Jun Seok, LEE, Jae Bin
Принадлежит:

A stable pharmaceutical preparation according to the present invention comprises: (A) an antibody or antigen-binding fragment thereof that binds to interleukin-6 receptor; (B) a surfactant; (C) a stabilizing agent; and (D) a buffer. Even in the case of comprising an antibody, and in particular, a high concentration of an antibody, the stable pharmaceutical preparation according to the present invention has low viscosity, has excellent long-term storage stability on the basis of excellent stability under accelerated and harsh conditions, and can be administered intravenously or subcutaneously.

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Номер записи: 3
03-02-2022 дата публикации

STABLE PHARMACEUTICAL PREPARATION

Номер: WO2022025660A1
Автор: KIM, Su Jung, KIM, Kwang Woo, ROH, Ji Won, SHIN, Yeon Kyeong, OH, Jun Seok, LEE, Jae Bin, HAN, Won Yong
Принадлежит:

A stable pharmaceutical preparation according to the present invention comprises: a recombinant fusion protein; a surfactant; a saccharide or a derivative thereof; and a buffer agent. The stable pharmaceutical preparation according to the present invention has a low viscosity while comprising a recombinant fusion protein, maintains excellent stability in long-term storage, accelerated, and severe conditions, and can be intraocularly administered.

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Номер записи: 4
19-07-2018 дата публикации

STABLE LIQUID PREPARATION

Номер: KR1020180082971A
Автор: LEE JOON WON, SHIN YEON KYEONG, KANG HYE YOUNG, KIM KWANG WOO, KIM SO YOUNG, KIM SU JUNG, OH JUN SEOK, HAN WON YONG
Принадлежит:

According to the present invention, a stable liquid preparation comprises: an antibody or an antigen binding site therefor; an acetate buffer; glycine; and a surfactant, without containing at least one of sugar, sugar alcohol, and a metal salt. The stable liquid preparation is stable even when containing high amount of antibodies, is excellent in terms of osmotic concentration and viscosity, and can be administered subcutaneously. COPYRIGHT KIPO 2018 ...

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Номер записи: 5
09-05-2018 дата публикации

STABLE PHARMACEUTICAL FORMULATION

Номер: KR1020180046888A
Автор: LEE, JOON WON, HAN, WON YONG, KIM, SU JUNG, OH, JUN SEOK, KIM, SO YOUNG, KIM, KWANG WOO, SHIN, YEON KYEONG
Принадлежит:

A stable pharmaceutical formulation according to the present invention is a stable pharmaceutical formulation which contains a fusion protein and a succinate salt buffer fused to an Fc domain of a human lgG and does not contain a stabilizer, wherein an extracellular ligand binding portion of a human p75 tumor necrosis factor receptor is fused. The stable pharmaceutical formulation according to the present invention enables long-term storage of a TNFR-Fc fusion protein formulation and provides excellent storage stability without a need to keep storage conditions complicated. The present invention is a simple formulation which does not contain stabilizer and thus is more economical than other stabilizing formulations. COPYRIGHT KIPO 2018 ...

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Номер записи: 6
03-05-2018 дата публикации

STABLE PHARMACEUTICAL FORMULATION

Номер: WO2018080196A2
Автор: LEE, Joon Won, HAN, Won Yong, KIM, Su Jung, OH, Jun Seok, KIM, So Young, KIM, Kwang Woo, SHIN, Yeon Kyeong
Принадлежит:

A stable pharmaceutical formulation according to the present invention comprises a fusion protein in which an extracellular ligand bonding domain of a human p75 tumor necrosis factor receptor is fused to an Fc domain of a human IgG, and a succinate buffer, and does not comprise a stabilizer. The stable pharmaceutical formulation according to the present invention allows long-term storage of a TNFR-Fc fusion protein formulation, and provides excellent storage stability without the need to strictly maintain storage conditions. The present invention is a simple formulation that does not comprise a stabilizer, and is more economical than other formulations that comprise a stabilizer.

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Номер записи: 7
15-02-2018 дата публикации

STABLE LIQUID PHARMACEUTICAL PREPARATION FOR ANTI-INFLUENZA VIRUS ANTIBODY

Номер: WO2018030777A1
Автор: LEE, Joon Won, HAN, Won Yong, KIM, Su Jung, OH, Jun Seok, KIM, So Young, KIM, Kwang Woo, SHIN, Yeon Kyeong
Принадлежит:

The present invention relates to a stable liquid pharmaceutical preparation for an anti-influenza virus antibody and, more specifically, to a stable liquid pharmaceutical preparation containing: (A) an anti-influenza virus antibody or a mixture of two or more different types of anti-influenza virus antibodies; (B) a surfactant; (C) a sugar or a sugar derivative; and (D) an amino acid. The stable liquid pharmaceutical preparation for an anti-influenza virus antibody of the present invention has excellent storage stability at low temperature (5°C), room temperature (25°C), and high temperature (40°C) and excellent long-term (12 months) storage stability, and can be administered intravenously, intramuscularly, intradermally, subcutaneously, intraperitoneal-locally, or in combinations thereof.

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Номер записи: 8
04-01-2018 дата публикации

STABLE LIQUID PHARMACEUTICAL PREPARATION

Номер: WO2018004260A1
Автор: LEE, Joon Won, HAN, Won Yong, KIM, Su Jung, OH, Jun Seok, KIM, So Young, HONG, Su Hyeon, SHIN, Yeon Kyeong
Принадлежит:

A stable liquid pharmaceutical preparation according to the present invention contains: an antibody or an antigen-binding fragment thereof; a surfactant; a sugar or a derivative thereof; and a buffer. The stable liquid pharmaceutical preparation according to the present invention has low viscosity while containing a high amount of the antibody, has excellent long-term storage stability on the basis of excellent stability under accelerated conditions and extreme conditions, and can be administered subcutaneously.

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Номер записи: 9
09-08-2018 дата публикации

STABLE PHARMACEUTICAL FORMULATION

Номер: WO2018080196A3
Автор: LEE, Joon Won, HAN, Won Yong, KIM, Su Jung, OH, Jun Seok, KIM, So Young, KIM, Kwang Woo, SHIN, Yeon Kyeong
Принадлежит:

A stable pharmaceutical formulation according to the present invention comprises a fusion protein in which an extracellular ligand bonding domain of a human p75 tumor necrosis factor receptor is fused to an Fc domain of a human IgG, and a succinate buffer, and does not comprise a stabilizer. The stable pharmaceutical formulation according to the present invention allows long-term storage of a TNFR-Fc fusion protein formulation, and provides excellent storage stability without the need to strictly maintain storage conditions. The present invention is a simple formulation that does not comprise a stabilizer, and is more economical than other formulations that comprise a stabilizer.

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Номер записи: 10
21-02-2018 дата публикации

STABLE LIQUID PHARMACEUTICAL PREPARATION FOR ANTI-INFLUENZA VIRUS ANTIBODY

Номер: KR1020180018393A
Автор: LEE, JOON WON, HAN, WON YONG, KIM, SU JUNG, OH, JUN SEOK, KIM, SO YOUNG, KIM, KWANG WOO, SHIN, YEON KYEONG
Принадлежит:

The present invention relates to a stable liquid pharmaceutical preparation for an anti-influenza virus antibody and, more specifically, to a stable liquid pharmaceutical preparation, which contains: (A) an anti-influenza virus antibody or a mixture of two or more different types of anti-influenza virus antibodies; (B) a surfactant; (C) a sugar or a sugar derivative; and (D) an amino acid. The stable liquid pharmaceutical preparation for an anti-influenza virus antibody of the present invention has excellent storage stability at low temperature (5°C), room temperature (25°C), and high temperature (40°C) and excellent long-term (12 months) storage stability, and can be administered intravenously, intramuscularly, intradermally, subcutaneously, intraperitoneal-locally, or in combinations thereof. COPYRIGHT KIPO 2018 ...

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Номер записи: 11
24-03-2023 дата публикации

안정한 액체 제제

Номер: KR102513828B1
Автор: 이준원, 신연경, 강혜영, 김광우, 김소영, 김수정, 오준석, 한원용
Принадлежит: (주)셀트리온

... 본 발명에 따른 안정한 액체 제제는 항체 또는 이의 항원 결합 부분; 아세트산염 완충액; 글리신; 및 계면활성제를 포함하고, 당, 당알코올, 및 금속염 중 하나 이상을 포함하지 않으며, 항체를 고함량으로 포함하는 경우에도 안정하고, 삼투질 농도 및 점도 면에서 우수하고, 피하 투여가 가능하다.

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Номер записи: 12
09-01-2018 дата публикации

STABLE LIQUID PHARMACEUTICAL PREPARATION

Номер: KR1020180003452A
Автор: LEE, JOON WON, HAN, WON YONG, KIM, SU JUNG, OH, JUN SEOK, KIM, SO YOUNG, HONG, SU HYEON, SHIN, YEON KYEONG
Принадлежит:

A stable liquid pharmaceutical preparation according to the present invention contains: an antibody or an antigen-binding fragment thereof; a surfactant; a sugar or a derivative thereof; and a buffer. The stable liquid pharmaceutical preparation according to the present invention has low viscosity while containing a high amount of the antibody, has excellent long-term storage stability on the basis of excellent stability under accelerated conditions and extreme conditions, and can be administered subcutaneously. COPYRIGHT KIPO 2018 ...

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Номер записи: 13