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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 15. Отображено 15.
02-08-2012 дата публикации

Systems and methods for determining volume of activation for deep brain stimulation

Номер: US20120197611A1
Автор: BUTSON Christopher R., Maks Christopher B., MCINTYRE Cameron C.
Принадлежит: THE CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, systems and methods for determining volume of activation for deep brain stimulation (“DBS”) using a finite element model (FEM) circuit to determine a FEM of an implanted electrode and a tissue medium in which the electrode is implanted, a Fourier FEM solver circuit to calculate a potential distribution in the tissue medium using information from the FEM circuit and a capacitive component of at least one of the implanted electrode and the tissue medium, and a volume of activation (VOA) circuit to predict a VOA using the potential distribution and a neuron model. 125-. (canceled)26. A computer system comprising: a finite element model (FEM) module to determine a FEM that models an implanted electrode and a tissue medium in which the electrode is implanted;', 'a Fourier FEM solver module to calculate a potential distribution in the tissue medium using information from the FEM module and a capacitive component of at least one of the electrode and the tissue medium; and', 'a volume of activation (VOA) module to provide a predicted VOA using the potential distribution and a neuron model., 'a processor configured to execute27. The system of claim 26 , wherein the processor is configured to calculate claim 26 , by the execution of the Fourier FEM solver module claim 26 , the potential distribution in the tissue medium using information from the FEM module and the capacitive component of the electrode.28. The system of wherein the processor is configured to calculate claim 26 , by the execution of the Fourier FEM solver module claim 26 , the potential distribution in the tissue medium using information from the FEM module and the capacitive component of the tissue medium.29. A computer system comprising: a finite element model (FEM) module to determine a FEM that models an implanted electrode, a tissue medium in which the electrode is implanted, and an electrode-tissue interface;', 'a Fourier FEM solver module to calculate a ...

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Номер записи: 1
27-12-2012 дата публикации

SYSTEM AND METHOD TO DESIGN STRUCTURE FOR DELIVERING ELECTRICAL ENERGY TO TISSUE

Номер: US20120330622A1
Автор: BUTSON Christopher R., McIntyre Cameron
Принадлежит: THE CLEVELAND CLINIC FOUNDATION

A computer-assisted method can include defining a target volume of tissue activation to achieve a desired therapeutic effect for an identified anatomic region. At least one parameter can be computed for an electrode design as a function of the defined target volume of tissue activation. The computed at least one parameter can be stored in memory for the electrode design, which parameter can be utilized to construct an electrode. 1. A computer-assisted method comprising:defining a target volume of tissue activation to achieve a desired therapeutic effect for an identified anatomic region;computing, b a computer processor, at least one parameter for an electrode design as a function of the defined target volume of tissue activation; andstoring, by the processor, the computed at least one parameter in a memory device for the electrode design.2. The method of claim 1 , wherein the at least one parameter comprises at least one structural parameter of at least one contact of the electrode design.3. The method of claim 2 , wherein the at least one contact has a length along a longitudinal axis thereof and a diameter claim 2 , the at least one structural parameter comprising at least one of the length and the diameter of the at least one contact.4. The method of claim 3 , wherein the at least one structural parameter comprises an aspect ratio defined by a ratio of the diameter and the length of the at least one contact claim 3 , the aspect ratio being constrained according to at least one of a shape and size of the target volume of tissue activation.5. The method of claim 2 , wherein the electrode design comprises a plurality of contacts spaced apart from each other along a longitudinal axis claim 2 , the at least one structural parameter further comprising a spacing between adjacent pairs of the plurality of contacts along the longitudinal axis.6. The method of claim 1 , wherein the computing of the at least one parameter further comprises:setting the at least one ...

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Номер записи: 2
31-01-2013 дата публикации

Method and device for displaying predicted volume of influence with patient-specific atlas of neural tissue

Номер: US20130030276A1
Автор: BUTSON Christopher R., Hall John D., Henderson Jaimie M., MCINTYRE Cameron C.
Принадлежит: THE CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location. 126-. (canceled)27. A computer-implemented method of outputting information concerning an electrode inserted inside a patient's neural tissue , the method comprising:determining, by a computer processor, an electric field in the patient's neural tissue, the electric field to be generated by the electrode;determining, by the processor and based on the determined electric field, an estimated volume of neural tissue activated by the determined electric field; andoutputting, by the processor, a graphical representation of the determined estimated volume.28. The method of claim 27 , wherein the outputting includes displaying the graphical representation relative to an anatomical atlas.29. The method of claim 28 , wherein the anatomical atlas is specific to the patient.30. The method of claim 29 , wherein the patient-specific anatomical atlas is generated by registering imaging data representing an anatomy of the patient's neural tissue with a canonical anatomical atlas. This application is a continuation of U.S. application Ser. No. 12/070,521, filed Feb. 19, 2008, which is hereby incorporated herein by reference in its entirety.This patent application pertains generally to neurosurgery and more particularly, ...

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Номер записи: 3
13-06-2013 дата публикации

SYSTEM AND METHOD TO DEFINE TARGET VOLUME FOR STIMULATION OF THE SPINAL CORD AND PERIPHERAL NERVES

Номер: US20130150922A1
Автор: BUTSON Christopher R., MCINTYRE Cameron C.
Принадлежит: THE CLEVELAND CLINIC FOUNDATION

One embodiment provides a computer-implemented method that includes storing a volume of tissue activation (VTA) data structure that is derived from analysis of a plurality of patients. Patient data is received for a given patient, the patient data representing an assessment of a patient condition. The VTA data structure is evaluated relative to the patient data to determine a target VTA for achieving a desired therapeutic effect for the given patient. 1. A computer-implemented method comprising:storing in a memory device a volume of tissue activation (VTA) data structure that is derived from analysis of a plurality of patients, wherein the tissue is the spinal cord;receiving, by a computer processor, patient data for a given patient, the patient data representing an assessment of a patient condition; andevaluating, by the computer processor, the VTA data structure relative to the patient data to determine a target VTA for achieving a desired therapeutic effect for the given patient.2. The method of claim 1 , wherein the target VTA has a boundary defined in a three-dimensional coordinate system for the patient.3. The method of claim 1 , further comprising determining at least one of a structural parameter and a stimulation parameter that can provide a design VTA that substantially matches the target VTA.4. The method of claim 3 , wherein the structural parameter comprises electrode design parameter data and the stimulation parameter comprises electrical stimulation parameter data.5. The method of claim 4 , further comprising selecting an electrode design according to the electrode design parameter data.6. The method of claim 5 , further comprising programming an implantable pulse generator according to the electrical stimulation parameter data for the selected electrode design such that application of the respective electrical stimulation data to an implanted electrode structure results in stimulation of tissue that substantially achieves the target VTA for the given ...

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Номер записи: 4
12-02-2015 дата публикации

METHOD AND DEVICE FOR DISPLAYING PREDICTED VOLUME OF INFLUENCE

Номер: US20150045852A1
Автор: BUTSON Christopher R., Hall John D., Henderson Jaimie M., MCINTYRE Cameron C.
Принадлежит:

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location. 126-. (canceled)27. A computer-implemented method of outputting information concerning an electrode inserted inside a patient's neural tissue , the method comprising:determining, by a computer processor, a distribution of electrical values, to be generated by the inserted electrode, in the patient's neural tissue in a region surrounding the inserted electrode;determining at least one threshold electrical value for neural tissue activation;determining, by the processor and by applying the at least one threshold value to the electrical values, an estimated volume of neural tissue activated by the distribution of electrical values; andoutputting, by the processor, a graphical representation of the determined estimated volume.28. The method of claim 27 , wherein the outputting includes displaying the graphical representation relative to an anatomical atlas.29. The method of claim 27 , further comprising determining conductivity at a plurality of tissue regions claim 27 , wherein the determination of the distribution of electrical values is based on the determined conductivity.30. The method of claim 29 , wherein the plurality of tissue regions span an anatomical area across which the determined conductivity ...

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Номер записи: 5
15-08-2019 дата публикации

Method and device for displaying predicted volume of influence

Номер: US20190247665A1
Автор: Cameron C. McIntyre, Christopher R. Butson, Jaimie M. Henderson, John D. Hall
Принадлежит: CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location.

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Номер записи: 6
30-11-2017 дата публикации

METHOD AND DEVICE FOR DISPLAYING PREDICTED VOLUME OF INFLUENCE

Номер: US20170344721A1
Автор: BUTSON Christopher R., Hall John D., Henderson Jaimie M., MCINTYRE Cameron C.
Принадлежит:

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location. 1. A system for determining an estimated volume of tissue activated by at least one electrode implanted inside a patient , the system comprising:a display device; and ["determining a distribution of electrical values to be generated by the at least one electrode using a first set of settings over a plurality of positions in the patient's tissue;", 'determining at least one threshold value for tissue activation;', 'determining, by applying the at least one threshold value to the electrical values, an estimated volume of tissue activated by the at least one electrode using the first set of settings; and', 'outputting, on the display device, a graphical representation of the determined estimated volume., 'a processor coupled to the display device and configured to perform steps comprising2. The system of claim 1 , wherein the outputting comprises displaying the graphical representation relative to an anatomical atlas.3. The system of claim 1 , wherein the steps further comprise determining conductivity at a plurality of tissue regions claim 1 , wherein the determination of the distribution of the electrical values is based on the determined conductivity.4. The system of claim 3 , wherein the determined ...

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Номер записи: 7
17-03-2015 дата публикации

Method and device for displaying predicted volume of influence with patient-specific atlas of neural tissue

Номер: US8983155B2
Автор: Cameron C. McIntyre, Christopher R. Butson, Jaimie M. Henderson, John D. Hall
Принадлежит: CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location.

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Номер записи: 8
10-06-2010 дата публикации

System and method to define target volume for stimulation in brain

Номер: CA2745435A1
Автор: Cameron C. McIntyre, Christopher R. Butson
Принадлежит: CLEVELAND CLINIC FOUNDATION

One embodiment provides a computer- implemented method that includes storing a volume of tissue activation (VTA) data structure that is derived from analysis of a plurality of patients. Patient data is received for a given patient, the patient data representing an assessment of a patient condition. The VTA data structure is evaluated relative to the patient data to determine a target VTA for achieving a desired therapeutic effect for the given patient.

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Номер записи: 9
12-01-2016 дата публикации

Brain stimulation models, systems, devices, and methods

Номер: US9235685B2
Автор: Cameron C. McIntyre, Christopher R. Butson, Jaimie M. Henderson, John D. Hall
Принадлежит: CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, a target volume of activation (VOA) can be received, a test VOA can be simulated, and at least one of a target electrode location or parameter can be provide using a relationship between the target VOA and the test VOA.

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Номер записи: 10
16-03-2010 дата публикации

System and method for obtaining a volume of influence based on non-uniform tissue conductivity data

Номер: US7680526B2
Автор: Cameron C. McIntyre, Christopher R. Butson, Jaimie M. Henderson, John D. Hall
Принадлежит: CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. A model computes a volume of influence region for a simulated electrical stimulation using certain stimulation parameters, such as amplitude, pulsewidth, frequency, pulse morphology, electrode contact selection or location, return path electrode selection, pulse polarity, etc. The model uses a non-uniform tissue conductivity. This accurately represents brain tissue, which has highly directionally conductive neuron pathways yielding a non-homogeneous and anisotropic tissue medium. In one example, the non-uniform tissue conductivity is obtained from diffusion tensor imaging (DTI) data. In one example, a second difference of an electric potential distribution is used to define a volume of activation (VOA) or similar volume of influence. In another example, a neuron or axon model is used to calculate the volume of influence without computing the second difference of the electric potential distribution.

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Номер записи: 11
17-09-2013 дата публикации

System and method to design structure for delivering electrical energy to tissue

Номер: US8538543B2
Автор: Cameron C. McIntyre, Christopher R. Butson
Принадлежит: CLEVELAND CLINIC FOUNDATION

A computer-assisted method can include defining a target volume of tissue activation to achieve a desired therapeutic effect for an identified anatomic region. At least one parameter can be computed for an electrode design as a function of the defined target volume of tissue activation. The computed at least one parameter can be stored in memory for the electrode design, which parameter can be utilized to construct an electrode.

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Номер записи: 12
15-09-2015 дата публикации

Method and system for displaying a volume of influence by an electrode inserted in neural tissue

Номер: US9135400B2
Автор: Cameron C. McIntyre, Christopher R. Butson, Jaimie M. Henderson, John D. Hall
Принадлежит: CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, a target volume of activation (VOA) can be received, a test VOA can be simulated, and at least one of a target electrode location or parameter can be provide using a relationship between the target VOA and the test VOA.

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Номер записи: 13
20-08-2009 дата публикации

Brain stimulation models, systems, devices, and methods

Номер: US20090208073A1
Автор: Cameron C. McIntyre, Christopher R. Butson, Jaimie M. Henderson, John D. Hall
Принадлежит: CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location.

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Номер записи: 14
12-09-2017 дата публикации

Method and device for displaying predicted volume of influence

Номер: US09760688B2
Автор: Cameron C. McIntyre, Christopher R. Butson, Jaimie M. Henderson, John D. Hall
Принадлежит: CLEVELAND CLINIC FOUNDATION

This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. In an example, volumetric imaging data representing an anatomical volume of a brain of a patient can be obtained and transformed to brain atlas data. A patient-specific brain atlas can be created using the inverse of the transformation to map the brain atlas data onto the volumetric imaging data and a volume of influence can be calculated using the patient-specific brain atlas. In certain examples, the volume of influence can include a predicted volume of tissue affected by an electrical stimulation delivered by an electrode at a corresponding at least one candidate electrode target location.

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Номер записи: 15