22-09-2022 дата публикации
Номер: US20220296221A1
Принадлежит:
The invention relates to a vaginal fluid monitoring device embedded into a feminine sanitary pad, said device comprising a stack of the following elements: An absorbent layer () configured to be in proximity to, and collect, a vaginal fluid; and A biosensing system () in fluidic connection with said absorbent layer (), said biosensing system () comprising: A microfluidic chip () configured to perform an immunoassay to detect the presence and/or the concentration of at least one target biomarker comprised in a vaginal fluid; Means () for providing a readout of the presence and/or the concentration of said at least one target biomarker; and An electrode array () located along the microfluidic chip () configured to detect and analyze the flow of said vaginal fluid by impedance means; wherein said immunoassay is configured to detect the presence and/or the concentration of at least one target biomarker indicative of a pre-term birth (PTB) risk and/or premature rupture of membrane (PROM) risk. The invention also relates to a method for detecting at least one target biomarker comprised in a vaginal fluid. 113-. (canceled)14. A vaginal fluid monitoring device embedded into a feminine sanitary pad , the device comprising:an absorbent layer configured to be in proximity to, and collect, a vaginal fluid; and a microfluidic chip configured to perform an immunoassay to detect a presence and/or a concentration of a target biomarker comprised in a vaginal fluid, the target biomarker indicative of a pre-term birth (PTB) risk and/or premature rupture of membrane (PROM) risk,', 'a readout device for providing a readout of the presence and/or the concentration of the target biomarker, and', 'an electrode array located along the microfluidic chip configured to detect and analyze a flow of the vaginal fluid by an impedance device., 'a biosensing system in fluidic connection with the absorbent layer, the biosensing system including,'}15. The monitoring device of claim 14 , wherein the ...
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