COMPOSITION BASED ON SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES THEREOF

The invention concerns compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives designed for therapeutic use. The inventive compositions are useful in particular for preventing or treating cardiovascular diseases, syndrome X, Ia restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders related to oxidative stress, for preventing or treating the effects of ageing in general and for example skin ageing, in particular in the field of cosmetics (occurrence of wrinkles and the like). 112-. (canceled)14. The method according to claim 13 , wherein the derivative corresponds to the cis or trans conformation or a mixture thereof.15. The method according to claim 13 , wherein X2 is a hydroxy group or an alkyloxy.16. The method according to claim 13 , wherein X4 is a group corresponding to the formula -G4-R4 and X2 is a hydroxy group or an alkyloxy group and claim 13 , G4 and R4 being such as defined in .17. The method according to claim 13 , wherein X1 represents a —R1 group or a group corresponding to the formula -G1-R1 claim 13 , where R1 is an alkyl group substituted by a substituent having the formula —COOR6 claim 13 , and G1 is as defined in .18. The method according to claim 13 , wherein X1 is a -G1-R1 group.19. The method according to claim 13 , wherein X1 is a -G1-R1 group in which G1 is an oxygen atom.20. The method according to claim 13 , wherein X4 represents a group corresponding to the formula -G4-R4 claim 13 , where R4 is an alkyl group substituted by a substituent having the formula —COOR6 claim 13 , and G4 being such as defined in .21. The method according to claim 13 , wherein X4 is a -G4-R4 group in which G4 is an oxygen atom.22. The method according to claim 13 , wherein X4 is a -G4-R4 group in which G4 is an oxygen atom claim 13 , and X3 or X5 respectively represents R3 and R5 claim 13 , with R3 and R5 being an alkyl ...

Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives, preparation and uses thereof

The invention concerns compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives designed for therapeutic use. The inventive compositions are useful in particular for preventing or treating cardiovascular diseases, syndrome X, Ia restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders related to oxidative stress, for preventing or treating the effects of ageing in general and for example skin ageing, in particular in the field of cosmetics (occurrence of wrinkles and the like).

Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives, preparation and uses thereof

The invention concerns compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives designed for therapeutic use. The inventive compositions are useful in particular for preventing or treating cardiovascular diseases, syndrome X, la restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders related to oxidative stress, for preventing or treating the effects of ageing in general and for example skin ageing, in particular in the field of cosmetics (occurrence of wrinkles and the like).

SUBSTITUTED 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES

La présente invention concerne des composés dérivés de 1,3-diphénylpropane substitués, les compositions pharmaceutiques les comprenant ainsi que leurs applications thérapeutiques, notamment dans les domaines de la santé humaine et animale.

NOVEL SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES

THERAPEUTIC USE OF GLYCEROLS ACYLES AND THEIR NITROGEN AND SULFUR ANALOGUES

ACYLATED AMINOPROPANEDIOLS AND THE LIKE AND THEIR THERAPEUTIC USES

SUBSTITUTED N- (BENZYL) PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION AND USES

DERIVED COMPOUND OF 1,3-DIPHENYLPROP-2-EN-1-ONE, PREPARATION AND USES

New acylated aminopropane diols and their analogs, useful in the treatment of cerebral vascular disorders especially cerebral ischemia and cerebral vascular accidents

Acylated aminopropane diols and their analogs (I), their optical and geometric isomers, racemates, salts, and mixtures. Acylated aminopropane diols and their analogs (I), their optical and geometric isomers, racemates, salts, and mixtures [Image] G2, G3 : O, S, or N-R4, with the proviso that they are not both N-R4; R, R4 : H, optionally saturated and optionally substituted 1-5C alkyl; R1, R2, R3 : H, CO-R5, or CO-(CH 2) 2 n + 1-X-R6, at least one of these being CO-(CH 2) 2 n + 1-X-R6; R5 : optionally saturated and optionally substituted alkyl, that may contain a cyclic group and having 1-25C atoms in the main chain; X : S, Se, SO, or SO 2; n : 0 - 11; R6 : optionally saturated and optionally substituted alkyl, that may contain a cyclic group and one or more hetero groups (O, S, Se, SO or SO 2) and having 3-23C atoms in the main chain with the exclusion of those compounds of formula (I) in which G2R2 and G3R3 are both OH groups. ACTIVITY : Cerebroprotective. MECHANISM OF ACTION : Peroxisome Proliferator-Activated Receptor activators.

COMPOSITION BASED ON SUBSTITUTED 1,3-DIPHENYLPROP-2EN-1-ONE DERIVATIVES, PREPARATION AND USES

La présente invention concerne des compositions comprenant des dérivés de 1,3-diphénylprop-2-èn-1-one substitués et leurs utilisations. Les compositions de l'invention sont utilisables notamment pour prévenir ou traiter les maladies cardiovasculaires, le syndrome X, la resténose, le diabète, l'obésité, l'hypertension, les maladies inflammatoires, les cancers ou néoplasmes (tumeurs bénignes ou malignes), les maladies neurodégénératives, dermatologiques et les désordres liés au stress oxydatif, pour prévenir ou traiter les effets du vieillissement en général et par exemple le vieillissement cutané, notamment dans le domaine cosmétique (l'apparition de rides, etc.). The present invention relates to compositions comprising substituted 1,3-diphenylprop-2-en-1-one derivatives and their uses. The compositions of the invention can be used in particular for preventing or treating cardiovascular diseases, syndrome X, restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative, dermatological diseases and disorders linked to oxidative stress, to prevent or treat the effects of aging in general and for example skin aging, in particular in the cosmetic field (the appearance of wrinkles, etc.).

Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives, preparations and uses thereof

La présente invention concerne des compositions comprenant des dérivés de 1,3~-diphénylprop-2-èn-1-one substitués destinées à un usage thérapeutique. Les compositions de l'invention sont utilisables notamment pour prévenir ou traiter les maladies cardiovasculaires, le syndrome X, la resténose, le diabète, l'obésité, l'hypertension, les maladies inflammatoires, les cancers ou néoplasmes (tumeurs bénignes ou malignes), les maladies neurodégénératives, dermatologiques et les désordres liés au stress oxydatif, pour prévenir ou traiter les effets du vieillissement en général et par exemple le vieillissement cutané, notamment dans le domaine cosmétique (l'apparition de rides, etc.). The present invention relates to compositions comprising derivatives of 1,3 ~ -substituted diphenylprop-2-en-1-one intended for therapeutic use. The compositions of the invention can be used in particular for preventing or treat cardiovascular disease, syndrome X, restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative diseases, dermatological and oxidative stress disorders, to prevent or treat the effects of aging in general and for example the skin aging, especially in the cosmetic field (the appearance of wrinkles, etc.).

Fatty Acid Compounds And Their Preparation And Uses

Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof

The present invention relates to substituted 1,3-diphenylpropane derivatives, to the pharmaceutical compositions containing them and to the therapeutic uses thereof, in particular in the fields of human and animal health.

Substituted n-(benzyl)phenylacetamide derivative compounds, preparation method thereof and uses of same as ppar ligands in the treatment of lipid and/or glucidic disorders

The invention relates to poly-substituted N-(benzyl)phenylacetamide-type derivatives having formula (I), pharmaceutical compositions containing same and the therapeutic use thereof as PPAR ligands, such as in the human and animal health fields for the treatment of lipid and/or glucidic metabolism disorders. The invention also relates to a method of preparing said derivatives.

Therapeutic use of acyl glycerols and the nitrogen- and sulphur-containing analogues therof

The invention relates to the therapeutic use of acyl glycerols and the nitrogen- and sulphur-containing analogues thereof, particularly in clinical applications. According to the invention, said compounds have advantageous pharmacological properties and are particularly of use for the prevention or treatment of neurodegenerative diseases.

Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof

Wynalazek dotyczy nowych podstawionych pochodnych 1,3-difenyloprop-2-en-1-onu, farmaceutycznych kompozycji zawierających te pochodne, ich zastosowań terapeutycznych, w szczególności do leczenia niedokrwienia mózgowego. Wynalazek dotyczy również sposobu otrzymywania tych pochodnych. The invention relates to new substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions containing these derivatives, their therapeutic uses, in particular for the treatment of cerebral ischemia. The invention also relates to a process for obtaining these derivatives.

Use of acylated glycerols and their nitrogen and sulfur analogs for the prevention and treatment of neurodegenerative disorders, e.g. Parkinson's disease

The use of acylated glycerols, and their nitrogen and sulfur analogs (I), their optical and geometric isomers, racemates, salts, hydrates, and mixtures, for the prevention and treatment of neurodegenerative disorders. The use of acylated glycerols, and their nitrogen and sulfur analogs (I), their optical and geometric isomers, racemates, salts, hydrates, and mixtures, for the prevention and treatment of neurodegenerative disorders. [Image] G1O or N-R; G2, G3O, S, N-R4, with the proviso that G1, G2, and G3 may not simultaneously represent N-R or N-R4; R, R4H or optionally substituted, optionally unsaturated 1-5C alkyl; R1, R2, R3H, CO-R5, CO-(CH2)2n+1-X-R6, with the proviso that at least one is CO-(CH2)2n+1-X-R6; R5optionally substituted, optionally unsaturated, optionally cyclic alkyl having 1-25 C atoms in the main chain; R6optionally substituted, optionally unsaturated, optionally cyclic alkyl having 3-23 C atoms in the main chain and optionally containing one or more hetero groups selected from O, S, Se, SO and SO2; X : S, Se, SO, or SO2; n : 0-11. ACTIVITY : Antiparkinsonian; Nootropic; Neuroprotective. MECHANISM OF ACTION : Alpha Peroxisome Proliferator-Activated Receptor (PPARalpha ) Agonist.

Substituted 1,3-diphenylprop-2-en-1-one derivatives, preparation and uses thereof

The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising same, their therapeutic uses, in particular for treating cerebral ischemia. The invention also concerns a method for preparing said derivatives.

Preparation of 1,3-diphenylprop-2-en-1-one derivatives

La présente invention concerne un procédé de préparation de dérivés de 1,3- diphénylprop-2-èn-1-one substitués sur un des deux groupes phényle par un groupement carboxyalkyloxy ou un groupement carboxyalkylthio. The present invention relates to a process for the preparation of 1,3-diphenylprop-2-en-1-one derivatives substituted on one of the two phenyl groups by a carboxyalkyloxy group or a carboxyalkylthio group.

NOVEL COMPOUNDS DERIVED FROM FATTY ACIDS, PREPARATION AND USES

Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof

The present invention concerns substituted 1,3-diphenylpropane derivatives, pharmaceutical compositions comprising them and the therapeutic uses thereof, particularly in the field of human and animal health.

Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives, preparation and uses thereof

Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof

Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof

La présente invention concerne de nouveaux dérivés de 1,3-diphénylprop-2-èn-1~one substitués, des compositions pharmaceutiques les comprenant, leurs applications en thérapeutique, notamment pour le traitement de l'ischémie cérébrale. Elle a également trait à un procédé de préparation de ces dérivés.

Substituted 1,3-diphenylprop-2-ene-1-one derivative and pharmaceutical compositions thereof, and process for the preparation thereof

Oppfinnelsen vedrører substituerte 1,3-difenylprop-2-en-11-on-derivater, farmasøytiske preparater som inneholder disse, terapeutiske anvendelser av dem, særlig for behandling av cerebral iskemi. Oppfinnelsen vedrører også en fremgangsmåte til fremstilling av derivatene. The invention relates to substituted 1,3-diphenylprop-2-en-11-one derivatives, to pharmaceutical compositions containing them, to therapeutic uses thereof, in particular for the treatment of cerebral ischemia. The invention also relates to a process for the preparation of the derivatives.

Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives, preparations and uses thereof

La présente invention concerne des compositions comprenant des dérivés de 1,3~-diphénylprop-2-èn-1-one substitués destinées à un usage thérapeutique. Les compositions de l'invention sont utilisables notamment pour prévenir ou traiter les maladies cardiovasculaires, le syndrome X, la resténose, le diabète, l'obésité, l'hypertension, les maladies inflammatoires, les cancers ou néoplasmes (tumeurs bénignes ou malignes), les maladies neurodégénératives, dermatologiques et les désordres liés au stress oxydatif, pour prévenir ou traiter les effets du vieillissement en général et par exemple le vieillissement cutané, notamment dans le domaine cosmétique (l'apparition de rides, etc.).

Composition intended for the treatment or prophylaxis of a condition linked to inflammation, neurodegeneration, deregulation of lipid and / or glycid metabolism, cell proliferation and / or differentiation and / or skin or central nervous system aging

"composição destinada ao tratamento ou à profilaxia de uma patologia ligada a inflamação, a neurodegenerescência, à desregularização do metabolismo lipídico e/ou glicídico, à proliferação e/ou à diferenciação celular e/ou ao envelhecimento cutâneo ou do sistema nervoso central, e, utilização de um composto". a presente invenção refere-se a composições dos derivados 1,3-difenilprop-2-en-1-ona substituídos destinados a um uso terapêutico. as composições da invenção são utilizáveis notadamente para prevenir ou tratar as doenças cardiovasculares, a sindrome x, a restenose, o diabetes, a obesidade, a hipertensão, as doenças inflamatórias, os cânceres ou neoplasmas (tumores benignos ou malignos), as doenças neurodegenerativas, dermatologias e os distúrbios ligados ao estresse oxidativo, para prevenir ou tratar os efeitos do envelhecimento em geral e por exemplo o envelhecimento cutâneo, notadamente no domínio cosmético (surgimento de rugas, etc.). "composition intended for the treatment or prophylaxis of a condition linked to inflammation, neurodegeneration, the deregulation of lipid and / or glycid metabolism, cell proliferation and / or differentiation and / or skin or central nervous system aging, and, use of a compound ". the present invention relates to compositions of substituted 1,3-diphenylprop-2-en-1-one derivatives intended for therapeutic use. the compositions of the invention are particularly useful for preventing or treating cardiovascular diseases, x-syndrome, restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative diseases, dermatologies and disorders linked to oxidative stress, to prevent or treat the effects of aging in general and, for example, skin aging, notably in the cosmetic field (appearance of wrinkles, etc.).

COMPOUNDS DERIVED FROM FATTY ACIDS, PREPARATION AND USES.

Compuesto de fórmula general (I): en la que: - G representa un átomo de oxígeno, un átomo de azufre o un grupo N-R4 en el que R4 es un átomo de hidrógeno o un grupo alquilo lineal o ramificado, saturado o no, opcionalmente sustituido, que tiene 1 a 5 átomos de carbono. - R1, R2 y R3, idénticos o diferentes, representan (i) un átomo de hidrógeno, (ii) un grupo CO-R en el que R es un grupo alquilo lineal o ramificado, saturado o no, opcionalmente sustituido, en el que la cadena principal tiene 1 a 25 átomos de carbono, o (iii) un grupo de fórmula CO-(CH2)2n+1-X-R'' en la que X es un átomo de azufre, un átomo de selenio, un grupo SO o un grupo SO2, n es un número entero comprendido entre 0 y 11, preferentemente igual a 0 ó 1 y R'' es un grupo alquilo lineal o ramificado, saturado o no, opcionalmente sustituido, en el que la cadena principal tiene de 13 a 23 átomos de carbono y opcionalmente uno o varios heterogrupos, preferentemente 0, 1 ó 2, más preferentemente 0 ó 1, seleccionado deentre un átomo de oxígeno, un átomo azufre, un átomo de selenio, un grupo SO y un grupo SO2, siendo uno o al menos los grupos R1, R2 y R3 un grupo de fórmula CO-(CH2)2n+1-X-R'' tal como se definió anteriormente. Compound of general formula (I): in which: - G represents an oxygen atom, a sulfur atom or an N-R4 group in which R4 is a hydrogen atom or a linear or branched alkyl group, saturated or not , optionally substituted, having 1 to 5 carbon atoms. - R1, R2 and R3, identical or different, represent (i) a hydrogen atom, (ii) a CO-R group in which R is a linear or branched alkyl group, saturated or not, optionally substituted, in which the main chain has 1 to 25 carbon atoms, or (iii) a group of formula CO- (CH2) 2n + 1-X-R '' in which X is a sulfur atom, a selenium atom, a group SO or a group SO2, n is an integer between 0 and 11, preferably equal to 0 or 1 and R '' is a linear or branched alkyl group, saturated or not, optionally substituted, in ...

Composition based on substituted 1,3-diphenyl prop-2-en-1-one derivatives

SUBSTITUTED N- (BENZYL) PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION AND USES

La présente invention concerne des dérivés du type N-(benzyl)phénylacétamide poly-substitués, les compositions pharmaceutiques les comprenant, leurs applications thérapeutiques, notamment dans les domaines de la santé humaine et animale. La présente invention a également trait à un procédé de préparation de ces dérivés. The present invention relates to poly-substituted N- (benzyl) phenylacetamide type derivatives, pharmaceutical compositions comprising them, their therapeutic applications, in particular in the fields of human and animal health. The present invention also relates to a process for the preparation of these derivatives.

1,3-diphenylprop-2-en-1-one derivative compounds, preparation method thereof and uses of same

The invention relates to substituted 1,3-diphenylprop-2-en-1-one derivative compounds, pharmaceutical and/or cosmetic compositions containing same, and the applications thereof in therapeutics and cosmetics. The invention also relates to a method for preparing said derivatives.

substituted 1,3-diphenylprop-2-en-1-one derivative, process for preparing compounds, pharmaceutical composition and use of at least one substituted 1,3-diphenylprop-2-en-1-one derivative

"derivado de 1,3-difenilprop-2-en-1-ona substituído, processo de preparação de compostos, composição farmacêutica e utilização de pelo menos um derivado de 1,3-difenilprop-2-en-1-ona substituído". a presente invenção refere-se a novos derivados de 1,3-difenilprop-2-en-1-ona substituídos, composições farmacêuticas que os compreendem, suas aplicações em terapêutica, notadamente para o tratamento da isquemia cerebral. ela igualmente trata de um processo de preparação desses derivados. "substituted 1,3-diphenylprop-2-en-1-one derivative, process for preparing compounds, pharmaceutical composition and use of at least one substituted 1,3-diphenylprop-2-en-1-one derivative". the present invention relates to new substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising them, their therapeutic applications, notably for the treatment of cerebral ischemia. it also deals with a process of preparing these derivatives.

Fatty acid compounds, preparation and uses thereof

Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof

Wynalazek dotyczy nowych podstawionych pochodnych 1,3-difenyloprop-2-en-1-onu, farmaceutycznych kompozycji zawierających te pochodne, ich zastosowań terapeutycznych, w szczególności do leczenia niedokrwienia mózgowego. Wynalazek dotyczy również sposobu otrzymywania tych pochodnych. The invention relates to new substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions containing these derivatives, their therapeutic uses, in particular for the treatment of cerebral ischemia. The invention also relates to a process for obtaining these derivatives.

THERAPEUTIC USE OF ACYLGLYCEROLS AND THEIR NITROGEN AND SULFIDE ANALOGS

La présente invention concerne l'utilisation d'acylglycérols et de leurs analogues azotés et sulfurés dans le domaine thérapeutique, notamment pour le traitement de l'ischémie cérébrale. Elle a également trait à des procédés de préparation de ces dérivés. Elle concerne aussi de nouveaux composés particuliers d'acylglycérols et de leurs analogues azotés et sulfurés et leurs procédés de préparation. The present invention relates to the use of acylglycerols and their nitrogen and sulfur analogues in the therapeutic field, in particular for the treatment of cerebral ischemia. It also relates to processes for the preparation of these derivatives. It also relates to new particular compounds of acylglycerols and their nitrogen and sulfur analogues and their preparation methods.

composition intended for the treatment or prophylaxis of a pathology linked to inflammation, neurodegeneration, deregulation of lipid and/or glucose metabolism, cell proliferation and/or differentiation and/or skin aging or the central nervous system

composição destinada ao tratamento ou à profilaxia de uma patologia ligada a inflamação, a neurodegenerescência, à desregularização do metabolismo lipídico e/ou glicídico, à proliferação e/ou à diferenciação celular e/ou ao envelhecimento cutâneo ou do sistema nervoso central, e, utilização de um composto. a presente invenção refere-se a composições dos derivados 1,3-difenilprop-2-en-1-ona substituídos destinados a um uso terapêutico. as composições da invenção são utilizáveis notadamente para prevenir ou tratar as doenças cardiovasculares, a sindrome x, a restenose, o diabetes, a obesidade, a hipertensão, as doenças inflamatórias, os cânceres ou neoplasmas (tumores benignos ou malignos), as doenças neurodegenerativas, dermatologias e os distúrbios ligados ao estresse oxidativo, para prevenir ou tratar os efeitos do envelhecimento em geral e por exemplo o envelhecimento cutâneo, notadamente no domínio cosmético (surgimento de rugas, etc.). composition intended for the treatment or prophylaxis of a pathology linked to inflammation, neurodegeneration, deregulation of lipid and/or glucose metabolism, cell proliferation and/or differentiation and/or skin aging or the central nervous system, and use of a compound. The present invention relates to compositions of substituted 1,3-diphenylprop-2-en-1-one derivatives intended for therapeutic use. the compositions of the invention are usable notably to prevent or treat cardiovascular diseases, syndrome x, restenosis, diabetes, obesity, hypertension, inflammatory diseases, cancers or neoplasms (benign or malignant tumors), neurodegenerative diseases, dermatology and disorders related to oxidative stress, to prevent or treat the effects of aging in general and, for example, skin aging, especially in the cosmetic domain (appearance of wrinkles, etc.).

Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof

The invention relates to the use of acyl glycerols and the nitrogen- and sulfur-containing analogues thereof in the therapeutic field, particularly in human health. The inventive compounds have advantageous pharmacological properties and are particularly of use for the prevention or treatment of neurodegenerative diseases.

Therapeutic use of acylglycerols and the nitrogen- and sulphur-containing analogues thereof

La présente invention concerne l'utilisation d'acylglycérols et de leurs analogues azotés et sulfurés dans le domaine thérapeutique, notamment pour le traitement de l'ischémie cérébrale. Elle a également trait à des procédés de préparation de ces dérivés. Elle concerne aussi de nouveaux composés particuliers d'acylglycérols et de leurs analogues azotés et sulfurés et leurs procédés de préparation. The present invention relates to the use of acylglycerols and their nitrogen and sulfur analogues in the therapeutic field, in particular for the treatment of cerebral ischemia. It also relates to processes for the preparation of these derivatives. It also relates to new particular compounds of acylglycerols and their nitrogen and sulfur analogues and their preparation methods.

Composition based on substituted 1,3-diphenylprop-2-en-1-one derivatives

Disclosed is a composition comprising at least one substituted 1, 3-diphenylprop-2-en-1-one derivatives of formula (I) for the treatment or prophylaxis of a pathology related to inflammation, neurodegeneration, deregulations of lipid and/or glucose metabolism, cell proliferation and/or differentiation and/or skin or central nervous system ageing.

Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof.

La presente invención se refiere a compuestos derivados de 1,3-difenilpropano sustituidos que poseen las propiedades agonistas de PPAR, composiciones farmacéuticas que los comprenden, así como sus aplicaciones terapéuticas, en particular, en el campo de la salud humana y animal.

Substituted 1,3-diphenylpropane derivatives, preparations and uses thereof

Preparation of 1,3-diphenylprop-2-en-1-one derivatives

Oppfinnelsen vedrører en fremgangsmåte til fremstilling av l,3-difenylprop-2-en-l-on- derivater substituert på den ene av de to fenylgrupper med en karboksyalkyloksygruppe eller en karboksyalkyltiogruppe.

1,3-diphenylprop-2-en-1-one derivative compounds, preparation method thereof and uses of same

Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof

The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising same, their therapeutic uses, in particular for treating cerebral ischemia. The invention also concerns a method for preparing said derivatives.

Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof

The invention concerns novel substituted 1,3-diphenylprop-2-en-1-one derivatives, pharmaceutical compositions comprising same, their therapeutic uses, in particular for treating cerebral ischemia. The invention also concerns a method for preparing said derivatives.

Herstellung von 1,3-diphenylprop-2-en-1- onderivaten

Zusammensetzung auf grundlage substituierter 1,3- diphenylprop-2-en-1-on-derivaten, deren herstellung und verwendungen

Substituierte 1,3-diphenylprop-2-en-1-on derivate,deren herstellung und anwendungen

Fettsäureverbindungen und deren herstellung und verwendungen