Event Dosimeter Device and Methods Thereof

A method including a dosimetry device having at least one sensor in a housing and a dosimetry processing device with a memory. The dosimtery processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the sensor; storing the readings; conducting an analysis of the stored readings to determine an injury risk assessment; and outputting at least one of the conducted analysis of the determined injury risk assessment or the stored readings. 1. A method comprising:providing a housing having at least one sensor in an ambient environment, the at least one sensor being configured to derive a plurality of parametric signals from a) acceleration readings generated from movement of the person, or b) pressure readings generated from perturbations propagating in the ambient environment, resulting from an identified event;providing personal medical history data corresponding to a person that is wearing or carrying the housing in the ambient environment, aggregate medical history data, and parametric data corresponding to the plurality of parametric signals;tailoring and adjusting an individualized injury threshold for the person based on the personal medical history data and the aggregate medical history data;storing the tailored and adjusted individualized injury threshold prior to the identified event;providing in real time an injury risk assessment corresponding to the identified event by comparing the stored personal injury threshold data to the parametric data; andproviding human perceivable indicia corresponding to the injury risk assessment data in response to a user assessment analysis request.2. The method of claim 1 , wherein the plurality of parametric signals includes at least one acceleration signal corresponding to the measured acceleration.3. The method of claim 2 , wherein the at least one acceleration signal provides ...

Ultra-Thin Nanometer Scale Polymeric Membranes

Ultra-thin nanometer-sealer freestanding polymeric membranes and methods for producing ultra-thin nanometer-scale freestanding recast membranes and ultra-thin nanometer-scale freestanding cross-linked membranes with solid internal backbone are disclosed. 1. A process for producing an ultra-thin nanometer-scale polymeric membrane comprising:forming a polymer film on a first side of a nanoporous substrate comprising a porous region and non-porous regions surrounding the porous region;swelling the polymer film on the first side of the nanoporous substrate by applying a solvent on a second side of the nanoporous substrate opposite the first side, which solvent migrates from the second side of the nanoporous substrate through the porous region to the first side of the nanoporous substrate; andsimultaneously shrinking the polymer film formed over the non-porous regions and stretching the film formed over the porous region on the first side of the nanoporous substrate by evaporating the solvent from the second side of the nanoporous substrate while limiting evaporation of the solvent from the first side of the nanoporous substrate.2. The process of claim 1 , wherein the forming a polymer film on a first side of a nanoporous substrate comprises:dispensing a solution of resin dispersion in a solvent over the first side of the nanoporous substrate;allowing the solution to spread over the porous region and non-porous regions of the first side of the nanoporous substrate; andallowing the solvent to evaporate yielding a thin film recast on the porous and non-porous regions of the first side of the nanoporous substrate.3. The process of claim 1 , wherein the evaporating the solvent from the second side of the nanoporous substrate while limiting evaporation of the solvent from the first side of the nanoporous substrate comprises confining the polymer film formed on first side of the nanoporous substrate in an enclosed space.4. The process of claim 1 , wherein the swelling the ...

System and method for listener controlled beamforming

A system and method for providing assistive listening for a plurality of listeners in an environment including a plurality of acoustic sources. A microphone array in combination with an acoustic beamforming processor configured to receive the acoustic signals within the environment and to process the acoustic signals based upon a target location of an acoustic signal selected on a listener-controlled interface device to generate a steered beam pattern. The acoustic beamforming processor further configured to transmit the steered beam pattern to the listener-controlled interface device based on the target location selected. The listener-controlled interface device configured to provide the steered beam pattern to an ear-level transducer of a hearing-impaired listener.

DEVICE PACKAGING FOR AN IMPACT DETECTION DEVICE

An impact detection device for detecting impacts to a body part of a user and various supporting systems are discussed. In an example, an impact detect device can include a circuit board, a component having a first section and a second section, a battery, and a molding for housing the circuit boat, the battery and the component. The circuit board can include impact detection circuitry including at least two sensors and a communication circuit. A zone of reduced rigidity can connect the first and second sections of the component, with the circuit board secured to the first section. The battery can be secured to the second section of the component allowing for flex relative to the circuit board. The molding can be shaped and dimensioned for mounting to a body part of the user. 120-. (canceled)21. A segmentally flexible package comprising: at least two sensors, the at least two sensors comprising a first accelerometer and at least one of a gyroscope and a second accelerometer;', 'a communication circuit to transmit data captured by the at least two sensors to a computer device; and', 'an integrated male connector comprising an extended portion of the circuit board with a plurality of connector pins disposed within a surface of the extended portion of the circuit board, wherein integrated male connector extends externally from a first side of the rigid section;, 'a rigid section encapsulating at least a portion of a circuit board populated with impact detection circuitry, the impact detect circuitry includinga flexible section encapsulating a battery electrically connected to the impact detection circuitry, the flexible section moldable to a radius at least partially conforming to an external surface adjacent the segmentally flexible package; anda flex zone coupling the rigid section to the flexible section, the flex zone in conjunction with the flexible section adapted to at least partially conform the segmentally flexible package to the external surface when the ...

Event dosimeter device and methods thereof

A method including a dosimetry device having at least one sensor in a housing and a dosimetry processing device with a memory. The dosimtery processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the sensor; storing the readings; conducting an analysis of the stored readings to determine an injury risk assessment; and outputting at least one of the conducted analysis of the determined injury risk assessment or the stored readings.

Apparatus, System and Method for Medical Analyses of Seated Individual

Apparatus, system and method for medical analysis of a seated individual, includes determining the aortic valve opening; the PTT; and calculating the PWV. Determining the aortic valve opening includes collecting BCG data while sitting on a seat and determining the timing of the aortic valve opening, taking into account posture. Measuring the aortic pulse wave transit time includes collecting BCG data while sitting on a seat capable of measuring changes in apparent weight; determining the timing of the aortic valve opening; detecting the arrival of the pulse wave at the end point; and measuring the relative timings of the two events. Calculating the PWV includes determining a length of the arterial segment through which a pulse wave is to be measured between a start point and an end point; and dividing the determined length of the arterial segment by the PTT.

Methods for monitoring exposure to an event and devices thereof

A method, non-transitory computer readable medium, and apparatus that includes obtaining, by a dosimetry computing device, sensor readings from at least one sensor. An event is identified, by the dosimetry computing device, based on at least one of one or more of the obtained sensor readings or one or more determinations based on the obtained sensor readings meeting one or more selection. At least one of the one or more determinations or the sensor readings which meet one or more of the selection criteria when the event is identified is stored by the dosimetry computing device.

EVENT DOSIMETER DEVICES AND METHODS THEREOF

A dosimetry device includes at least one sensor in a housing and a dosimetry processing device with a memory. The dosimtery processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the sensor; storing the readings; conducting an analysis of the stored readings to determine an injury risk assessment; and outputting at least one of the conducted analysis of the determined injury risk assessment or the stored readings. 1. A dosimetry device comprising:at least one sensor; anda dosimetry processing device with a memory coupled to the at least one sensor in the housing, the dosimetry processing device configured to execute programmed instructions stored in the memory comprising obtaining readings from the at least one sensor, storing the readings, conducting an analysis of the stored readings to determine an injury risk assessment, and outputting at least one of the conducted analysis of the injury risk assessment or the stored readings.2. The device as set forth in wherein the dosimetry processing device is configured to execute programmed instructions stored in the memory for the obtaining further comprising obtaining a time and date stamp with each of the obtained readings and the storing further comprises storing the time and date stamp with each of the obtained readings.3. The device as set forth in wherein the at least one sensor is a pressure sensor.4. The device as set forth in wherein the sensor is an accelerometer.5. The device as set forth in wherein the accelerometer is a three-axis accelerometer.6. The device as set forth in wherein the accelerometer is configured to obtain linear acceleration readings in real time.7. The device as set forth in wherein the sensor is a gyroscope.8. The device as set forth in wherein the gyroscope is configured to obtain rotational acceleration readings.9. The device as set ...

DEVICES, SYSTEMS AND METHODS FOR DETECTING AND EVALUATING IMPACT EVENTS

An impact detection device for detecting impacts to a body part of a user and various supporting systems are discussed. In an example, an impact detect device can include a circuit board, a component having a first section and a second section, a battery, and a molding for housing the circuit boat, the battery and the component. The circuit board can include impact detection circuitry including at least two sensors and a communication circuit. A zone of reduced rigidity can connect the first and second sections of the component, with the circuit board secured to the first section. The battery can be secured to the second section of the component allowing for flex relative to the circuit board. The molding can be shaped and dimensioned for mounting to a body part of the user. 1. An impact detection device for detecting impact to a body part of a user , the device comprising: at least two sensors, the at least two sensors comprising a first accelerometer and at least one of a gyroscope and a second accelerometer;', 'a communication circuit to transmit data captured by the at least two sensors to a mobile device; and', 'an integrated male USB connector comprising an extended portion of the circuit board with a plurality of connector pins disposed within a surface of the extended portion of the circuit board;, 'a circuit board including impact detection circuitry comprisinga component having a first section and a second section connected by a flex zone, a portion of the circuit board excluding the integrated male USB connector secured to the first section, wherein the component includes a length, a width, and a thickness, where the length and the width are substantially greater than the thickness to create a major surface to abut an external body part and the flex zone extends along the width to allow bending of the major surface at least between the first second and the second section, and wherein the flex zone allows for deflection of the second section with respect ...

DEVICES, SYSTEMS AND METHODS FOR DETECTING AND EVALUATING IMPACT EVENTS

An impact detection device for detecting impacts to a body part of a user and various supporting systems are discussed. In an example, an impact detect device can include a circuit board, a component having a first section and a second section, a battery, and a molding for housing the circuit boat, the battery and the component. The circuit board can include impact detection circuitry including at least two sensors and a communication circuit. A zone of reduced rigidity can connect the first and second sections of the component, with the circuit board secured to the first section. The battery can be secured to the second section of the component allowing for flex relative to the circuit board. The molding can be shaped and dimensioned for mounting to a body part of the user. 1. An impact detection device for detecting impact to a body part of a user , the device comprising: at least two sensors, the at least two sensors comprising a first accelerometer and at least one of a gyroscope and a second accelerometer; and', 'a communication circuit to transmit data captured by the at least two sensors to a mobile device;, 'a circuit board including impact detection circuitry comprisinga component having a first section and a second section connected by a zone of reduced rigidity, the circuit board secured to the first section;a battery mounted to the second section to allow the battery to flex relative to the circuit board; anda molding for housing the circuit board, the battery and the component, wherein the housing is shaped and dimensioned for mounting to the body part of the user.2. The impact detection device of claim 1 , wherein the component claim 1 , the circuit board claim 1 , and the battery form a unified and continuous unit including at least one contiguous surface.3. The impact detection device of claim 2 , wherein the formable battery is at least partially encapsulated by the component; andwherein the component is a molded polymer material.4. The impact ...

Pulse Wave Velocity, Arterial Compliance, and Blood Pressure

Disclosed are methods for determining physiological parameters of an individual including blood pressure, arterial compliance, flow velocity, and pressure wave velocity. A noninvasive method for determining the blood pressure of a patient is based on measurements of flow velocity, pulse wave velocity and arterial compliance. A noninvasive method for determining the arterial compliance of a patient is based on measurements of blood pressure, flow velocity, and pulse wave velocity.

SYSTEMS AND METHODS FOR MAPPING AN EXPLOSIVE EVENT

Systems and methods for mapping an explosive event are discussed. In an example, a system for mapping an explosive event can include a plurality of sensor devices and a data analysis system. Each of the plurality of sensor devices can include an environmental sensor to measure at least one parameter of an explosive event. Each sensor device can also include a time synchronization circuit to synchronize time stamping of the parameter measured by the environmental sensor, and a wireless communication interface. The data analysis system can access measurement data generated by the plurality of sensor devices and analyze the measurement data to produce a visualization mapping the measurements onto a virtual representation of the test environment. 1. A system for dynamic mapping of explosive events within a test environment , the system including: a environmental sensor to measure at least one parameter of an explosive event;', 'a time synchronization circuit to synchronize time stamping of the at least one parameter measured by the environmental sensor; and', 'a communication interface; and, 'a plurality of sensor devices, each sensor device including access measurement data collected from the plurality of sensor devices during an explosive event; and', 'analyze the measurement data to produce a dynamic visualization of the at least one parameter mapped onto a virtual representation of the test environment., 'a data analysis system including a processor and a memory device, the memory device including instructions that, when executed by the data analysis system, cause the data analysis system to2. The system of claim 1 , wherein the instructions that cause the data analysis system to analyze the measurement data include instructions to divide the measurement data into time intervals based on time stamps included in the measurement data and generate a visualization snapshot for each time interval.3. The system of claim 2 , wherein the instructions that cause the data ...

Capsule, in-line magnetic valve system and method

A capsule is disclosed which includes a flexible outer shell capable of transforming into an asymmetric shape; an internal medium encapsulated by the outer shell, the medium including a plurality of magnetic particles, wherein the magnetic particles can move in response to an applied magnetic field. A valve system includes an in-line valve sized to fit within a flow channel including a capsule having a flexible outer shell containing an internal medium encapsulated by the outer shell, the medium including a plurality of magnetic particles; and a magnetic field source disposed about the exterior wall of the channel.

Noninvasive Diagnostics of Proximal Heart Health Biomarkers

An integrated bioinstrumentation system, combining an accurate and robust quasi 1D computational model with experimental peripheral measurements, is designed to extract information on other quantities of interest, for which the direct measurements are not feasible. The system is able to quantify and visualize the distributions of a cardiac output (CO), aortic blood pressure (BP), flow, velocity, and aortic arterial compliance, based on a peripheral analysis of a pulse transit time (PTT) measured at the available peripheral sites. A preliminary calibration stage extracts the arterial properties from simultaneous measurements of a pulse transit time, and an upper arm blood pressure. Obtained transfer functions, linking noninvasive peripheral measurements to the aortic pressure, cardiac output, aortic compliance and others serve to quantify the indicators of cardiac morbidity and mortality. 1. A method for noninvasive diagnostics of proximal heart health biomarkers of an individual , comprising:identifying a cardiovascular sub-system, comprising a) a single proximal section comprising an arterial network associated with the heart, b) a plurality of distal sections and c) a plurality of cut-off sections of the identified sub-system, of the individual;calibrating properties of the arterial network and boundary conditions by measuring a) BP at multiple locations along the sub-system, b) PTT at a location of a distal section of the plurality of distal sections, and c) a CO and an arterial diameter of the individual;constructing a patient-specific model by integrating the calibrated properties into a differential physics-based fluid-structure interaction (FSI) model;obtaining non-invasive BP and PTT diagnostic measurements in a vicinity of the location of the distal section;running the patient-specific model in various iterations of CO until approaching the non-invasively measured BP and PTT at the distal location computing a dependency of the CO on the PTT and BP of the ...

Apparatus, System and Method for Medical Analyses of Seated Individual

Apparatus, system and method for medical analysis of a seated individual, includes determining the aortic valve opening; the PTT; and calculating the PWV. Determining the aortic valve opening includes collecting BCG data while sitting on a seat and determining the timing of the aortic valve opening, taking into account posture. Measuring the aortic pulse wave transit time includes collecting BCG data while sitting on a seat capable of measuring changes in apparent weight; determining the timing of the aortic valve opening; detecting the arrival of the pulse wave at the end point; and measuring the relative timings of the two events. Calculating the PWV includes determining a length of the arterial segment through which a pulse wave is to be measured between a start point and an end point; and dividing the determined length of the arterial segment by the PTT.

Pulse Energy Manipulation of Material Properties

Material properties are manipulated using rapid pulse application of energy in combination with applied electric or magnetic fields. When sintering, annealing or crystallizing a target film, the pulse repetition cycle can be constrained to ensure material temperature rises above and falls below the Curie temperature before the next energy pulse. This process results in enhanced material properties as compared to traditional techniques having a single, slow temperature excursion and subsequent application of the applied external field. 1. A process for manipulating material properties of a target film , comprising:applying repeated pulsed energy, comprising a total energy, cycle time, duration, and time between each pulse, while simultaneously applying an electric field or a magnetic field to the target film facilitating dipole reorientation resulting in enhanced material properties of the target film.2. The process of claim 1 , wherein the target film comprises a ferroelectric material when the electric field is applied.3. The process of claim 2 , wherein the dipole reorientation comprises electric dipole reorientation.4. The process of claim 3 , wherein the enhanced material properties comprise piezoelectric properties and sensitivity.5. The process of claim 1 , wherein the target film comprises a magnetic material when the magnetic field is applied.6. The process of claim 5 , wherein the dipole reorientation comprises magnetic dipole reorientation.7. The process of claim 6 , wherein the enhanced material properties comprise magnetic properties.8. The process of claim 1 , wherein the pulsed energy is sourced from a photonic flash lamp claim 1 , electric current induced resistive heating claim 1 , laser illumination claim 1 , radiation claim 1 , UV illumination claim 1 , or AC magnetic field application.9. The process of claim 1 , wherein the target film comprises a sintered claim 1 , crystallized claim 1 , or annealed material.10. The process of claim 1 , further ...

Blood Pressure and Arterial Compliance Estimation from Arterial Segments

A noninvasive method for monitoring the blood pressure and arterial compliance of a patient based on measurements of a flow velocity and a pulse wave velocity is described. An embodiment uses a photoplethysmograph and includes a method to monitor the dynamic behavior of the arterial blood flow, coupled with a hemodynamic mathematical model of the arterial blood flow motion in a fully nonlinear vessel. A derived mathematical model creates the patient specific dependence of a blood pressure versus PWV and blood velocity, which allows continuous monitoring of arterial blood pressure. 1. A method for determining material characteristics for an artery , the method comprising:providing at least three values for each of blood pressure, internal radius, and external radius of an arterial segment or segments of a subject;applying a base model of fluid-structure interaction incorporating conservation of mass and momentum for the fluid, and non-linear elasticity of the structure; andrunning a mathematical optimization on the base model to provide a calibrated model to determine material characteristics of the arterial segment or segments.4. A method for determining at least one of a blood pressure and an arterial compliance parameter of a subject , the method comprising;providing a value for pulse wave velocity within an arterial segment or segments of a subject;providing a value for flow velocity within the arterial segment or segments of the subject;providing a value for blood density of the subject;providing the material characteristics of an artery; andapplying a calibrated model of fluid-structure interaction incorporating conservation of mass and momentum for the fluid, and non-linear elasticity of the structure, to calculate at least one of blood pressure and an arterial compliance parameter of the subject using the provided values.5. The method of claim 4 , wherein the flow velocity is measured directly from the subject.6. The method of claim 4 , wherein the flow ...

Systems, devices, and methods for measuring body temperature of a subject using characterization of feces and/or urine

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects urinating or defecating into an excretion collection device, including systems, devices, and methods for monitoring temperature of objects (e.g., urine or feces) received through the opening of the excretion collection device. In some embodiments, systems, devices, and methods disclosed herein include a temperature sensor that can generate a temperature profile associated with a urination or defecation event, and determine a core body temperature of a subject based on the temperature profile.

SYSTEMS, DEVICES, AND METHODS FOR MEASURING LOADS AND FORCES OF A SEATED SUBJECT USING SCALE DEVICES

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects seated on a toilet, including systems, devices, and methods for monitoring loads and forces on a scale device. In some embodiments, systems, devices, and methods disclosed herein include a set of sensors that can measure loads and forces present at a scale device receiving the feet of an individual seated in a toilet.

Method for monitoring exposure to an event and device thereof

A method, non-transitory computer readable medium, and apparatus that includes obtaining, by a dosimetry computing device, sensor readings from at least one sensor. An event is identified, by the dosimetry computing device, based on at least one of one or more of the obtained sensor readings or one or more determinations based on the obtained sensor readings meeting one or more selection. At least one of the one or more determinations or the sensor readings which meet one or more of the selection criteria when the event is identified is stored by the dosimetry computing device.

Event monitoring dosimetry apparatuses and methods thereof

A dosimetry apparatus includes at least one sensor in a housing, a cover configured to permit compression waves to pass through, the cover is seated over the at least one sensor, and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the at least one sensor; storing the readings with a time and date stamp when obtained; conducting an analysis based on the obtained readings; and outputting at least one of the stored readings or the conducted analysis.

Peristaltic micropumps and fluid delivery devices that incorporate them

In one embodiment, a peristaltic micropump comprising a substrate having a first side and a second side, a microtube that extends across the first side of the substrate, and multiple pump actuators formed on the first side of the substrate and positioned adjacent to the microtube at discrete, spaced positions along the length of the microtube, wherein the micropump is configured to sequentially actuate the pump actuators so as to create peristaltic action that drives fluid contained in the microtube along the length of the tube.

Event dosimeter device and methods thereof

A dosimetry device includes at least one sensor in a housing and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the sensor; storing the readings; conducting an analysis of the stored readings to determine an injury risk assessment; and outputting at least one of the conducted analysis of the determined injury risk assessment or the stored readings.

Apparatus, method, and computer program product for quantitative analysis of a nucleic acid amplification reaction

Event monitoring dosimetry apparatuses and methods thereof

A dosimetry apparatus includes at least one sensor in a housing, a cover configured to permit compression waves to pass through, the cover is seated over the at least one sensor, and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the at least one sensor; storing the readings with a time and date stamp when obtained; conducting an analysis based on the obtained readings; and outputting at least one of the stored readings or the conducted analysis.

Event dosimeter device and methods thereof

A dosimetry device includes at least one sensor in a housing and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the sensor; storing the readings; conducting an analysis of the stored readings to determine an injury risk assessment; and outputting at least one of the conducted analysis of the determined injury risk assessment or the stored readings.

Event dosimeter devices and methods thereof

A dosimetry device includes at least one sensor in a housing and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the sensor; storing the readings; conducting an analysis of the stored readings to determine an injury risk assessment; and outputting at least one of the conducted analysis of the determined injury risk assessment or the stored readings.

Blast sensor performance improvement

Systems and methods to reduce light transmission to a sensing element of a blast sensor are disclosed, including a light attenuation material to cover at least a portion of the blast sensor to reduce false detection of impulse noise or shock wave events by the sensing element of the blast sensor. The light attenuation material can include a pigmented gel having a specific pigment concentration and thickness to reduce false detection of events while maintaining performance of detection of impulse noise or shock wave events.

Event monitoring dosimetry apparatuses and methods thereof

A dosimetry apparatus includes at least one sensor in a housing, a cover configured to permit compression waves to pass through, the cover is seated over the at least one sensor, and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the at least one sensor; storing the readings with a time and date stamp when obtained; conducting an analysis based on the obtained readings; and outputting at least one of the stored readings or the conducted analysis.

Noninvasive diagnostics of proximal heart health biomarkers

An integrated bioinstrumentation system, combining an accurate and robust quasi 1D computational model with experimental peripheral measurements, is designed to extract information on other quantities of interest, for which the direct measurements are not feasible. The system is able to quantify and visualize the distributions of a cardiac output (CO), aortic blood pressure (BP), flow, velocity, and aortic arterial compliance, based on a peripheral analysis of a pulse transit time (PTT) measured at the available peripheral sites. A preliminary calibration stage extracts the arterial properties from simultaneous measurements of a pulse transit time, and an upper arm blood pressure. Obtained transfer functions, linking noninvasive peripheral measurements to the aortic pressure, cardiac output, aortic compliance and others serve to quantify the indicators of cardiac morbidity and mortality.

Noninvasive diagnostics of proximal heart health biomarkers

An integrated bioinstrumentation system, combining an accurate and robust quasi 1D computational model with experimental peripheral measurements, is designed to extract information on other quantities of interest, for which the direct measurements are not feasible. The system is able to quantify and visualize the distributions of a cardiac output (CO), aortic blood pressure (BP), flow, velocity, and aortic arterial compliance, based on a peripheral analysis of a pulse transit time (PTT) measured at the available peripheral sites. A preliminary calibration stage extracts the arterial properties from simultaneous measurements of a pulse transit time, and an upper arm blood pressure. Obtained transfer functions, linking noninvasive peripheral measurements to the aortic pressure, cardiac output, aortic compliance and others serve to quantify the indicators of cardiac morbidity and mortality.

Microelectronic biosensor and method of monitoring cultured cells

Host supported genetic biosensors

The present invention relates to an in vivo method of monitoring an analyte in a subject. This method involves providing an expression vector that encodes a biosensor molecule, the biosensor molecule comprising an analyte binding domain and a signal domain. The biosensor molecule produces a signal from the signal domain upon binding of the analyte by the analyte binding domain. The signal is detectable by a non-invasive means. The expression vector is introduced locally into in vivo cells of a subject under conditions effective to express the biosensor molecule in the cells. The signal from the expressed biosensor molecule is detected by a non-invasive means, thereby monitoring the analyte in the subject in vivo.

Systems, devices, and methods for measuring loads and forces of a seated subject using scale devices

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects seated on a toilet, including systems, devices, and methods for monitoring loads and forces on a scale device. In some embodiments, systems, devices, and methods disclosed herein include a set of sensors that can measure loads and forces present at a scale device receiving the feet of an individual seated in a toilet.

Acoustic monitoring systems and methods

Systems and methods to provide acoustic monitoring are disclosed, comprising receiving a first acoustic signal and providing a first analog signal output representative of the received first acoustic signal using a first sensor, determining at least one of a continuous noise level of the first analog signal output of the first sensor or a peak level of impulse noise of the first analog signal output of the first sensor using analog signal processing circuitry, and sampling, using digital signal processing circuitry, at least one of the determined continuous noise level of the first analog signal output or the peak level of impulse noise of the first analog signal output from the analog signal processing circuitry to provide data privacy of the first analog signal output.

Acoustic monitoring systems and methods

Systems and methods to provide acoustic monitoring are disclosed, comprising receiving a first acoustic signal and providing a first analog signal output representative of the received first acoustic signal using a first sensor, determining at least one of a continuous noise level of the first analog signal output of the first sensor or a peak level of impulse noise of the first analog signal output of the first sensor using analog signal processing circuitry, and sampling, using digital signal processing circuitry, at least one of the determined continuous noise level of the first analog signal output or the peak level of impulse noise of the first analog signal output from the analog signal processing circuitry to provide data privacy of the first analog signal output.

Pulse Wave Velocity, Arterial Compliance, and Blood Pressure

Disclosed are methods for determining physiological parameters of an individual including blood pressure, arterial compliance, flow velocity, and pressure wave velocity. A noninvasive method for determining the blood pressure of a patient is based on measurements of flow velocity, pulse wave velocity and arterial compliance. A noninvasive method for determining the arterial compliance of a patient is based on measurements of blood pressure, flow velocity, and pulse wave velocity.

Blood pressure and arterial compliance estimation from arterial segments

Urządzenia dozymetryczne do monitorowania zdarzeń i ich sposoby

Hændelsesovervågningsdosimetriindretninger og fremgangsmåder dertil

Systems, devices, and methods for measuring loads and forces of a seated subject using scale devices

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects seated on a toilet, including systems, devices, and methods for monitoring loads and forces on a scale device. In some embodiments, systems, devices, and methods disclosed herein include a set of sensors that can measure loads and forces present at a scale device receiving the feet of an individual seated in a toilet.

Event monitoring dosimetry apparatuses and methods thereof

A dosimetry apparatus includes at least one sensor in a housing, a cover configured to permit compression waves to pass through, the cover is seated over the at least one sensor, and a dosimetry processing device with a memory. The dosimetry processing device is coupled to the at least one sensor in the housing. The dosimetry processing device is configured to execute programmed instructions stored in the memory comprising: obtaining readings from the at least one sensor; storing the readings with a time and date stamp when obtained; conducting an analysis based on the obtained readings; and outputting at least one of the stored readings or the conducted analysis.

Systems, devices, and methods for measuring loads and forces of a seated subject using scale devices

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects seated on a toilet, including systems, devices, and methods for monitoring loads and forces on a scale device. In some embodiments, systems, devices, and methods disclosed herein include a set of sensors that can measure loads and forces present at a scale device receiving the feet of an individual seated in a toilet.

Pulse Energy Manipulation of Material Properties

Material properties are manipulated using rapid pulse application of energy in combination with applied electric or magnetic fields. When sintering, annealing or crystallizing a target film, the pulse repetition cycle can be constrained to ensure material temperature rises above and falls below the Curie temperature before the next energy pulse. This process results in enhanced material properties as compared to traditional techniques having a single, slow temperature excursion and subsequent application of the applied external field.

Systems, devices, and methods for measuring body temperature of a subject using characterization of feces and/or urine

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects urinating or defecating into an excretion collection device, including systems, devices, and methods for monitoring temperature of objects (e.g., urine or feces) received through the opening of the excretion collection device. In some embodiments, systems, devices, and methods disclosed herein include a temperature sensor that can generate a temperature profile associated with a urination or defecation event, and determine a core body temperature of a subject based on the temperature profile.

Host supported genetic biosensors

The present invention relates to an in vivo method of monitoring an analyte in a subject. This method involves providing an expression vector that encodes a biosensor molecule, the biosensor molecule comprising an analyte binding domain and a signal domain. The biosensor molecule produces a signal from the signal domain upon binding of the analyte by the analyte binding domain. The signal is detectable by a non-invasive means. The expression vector is introduced locally into in vivo cells of a subject under conditions effective to express the biosensor molecule in the cells. The signal from the expressed biosensor molecule is detected by a non-invasive means, thereby monitoring the analyte in the subject in vivo.

Systems, devices, and methods for measuring body temperature of a subject using characterization of feces and/or urine

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects urinating or defecating into an excretion collection device, including systems, devices, and methods for monitoring temperature of objects (e.g., urine or feces) received through the opening of the excretion collection device. In some embodiments, systems, devices, and methods disclosed herein include a temperature sensor that can generate a temperature profile associated with a urination or defecation event, and determine a core body temperature of a subject based on the temperature profile.

Systems, devices, and methods for measuring body temperature of a subject using characterization of feces and/or urine

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects urinating or defecating into an excretion collection device, including systems, devices, and methods for monitoring temperature of objects (e.g., urine or feces) received through the opening of the excretion collection device. In some embodiments, systems, devices, and methods disclosed herein include a temperature sensor that can generate a temperature profile associated with a urination or defecation event, and determine a core body temperature of a subject based on the temperature profile.

Vocal acoustic attenuation

Systems and methods to provide vocal acoustic attenuation for an acoustic sensor are disclosed, comprising attenuating an acoustic signal using an attenuation material covering at least a portion of a first surface of the acoustic sensor.

Acoustic monitoring systems and methods

Systems and methods to provide acoustic monitoring are disclosed, comprising receiving a first acoustic signal and providing a first analog signal output representative of the received first acoustic signal using a first sensor, determining at least one of a continuous noise level of the first analog signal output of the first sensor or a peak level of impulse noise of the first analog signal output of the first sensor using analog signal processing circuitry, and sampling, using digital signal processing circuitry, at least one of the determined continuous noise level of the first analog signal output or the peak level of impulse noise of the first analog signal output from the analog signal processing circuitry to provide data privacy of the first analog signal output.

Acoustic monitoring systems and methods

Noninvasive diagnostics of proximal heart health biomarkers

Blood pressure and arterial compliance estimation from arterial segments

A noninvasive method for monitoring the blood pressure and arterial compliance of a patient based on measurements of a flow velocity and a pulse wave velocity is described. An embodiment uses a photoplethysmograph and includes a method to monitor the dynamic behavior of the arterial blood flow, coupled with a hemodynamic mathematical model of the arterial blood flow motion in a fully nonlinear vessel. A derived mathematical model creates the patient specific dependence of a blood pressure versus PWV and blood velocity, which allows continuous monitoring of arterial blood pressure.

Vocal acoustic attenuation

Vocal acoustic attenuation

Systems and methods to provide vocal acoustic attenuation for an acoustic sensor are disclosed, comprising attenuating an acoustic signal using an attenuation material covering at least a portion of a first surface of the acoustic sensor.

Photoplethysmography sensing module, systems and devices thereof

Systems, devices, and methods are disclosed herein for monitoring physiological data of subjects seated on a toilet, including systems, devices, and methods for monitoring light signals or readings on a toilet seat. In some embodiments, systems, devices, and methods disclosed herein include a set of sensors integrated into a seat (e.g., of a toilet), with the sensors being configured to measure multiple light signals associated with unique optical paths across a portion of tissue of an individual seated on the seat.

Systems and methods for mapping an explosive event

Systems and methods for mapping an explosive event are discussed. In an example, a system (400) for mapping an explosive event can include a plurality of sensor devices (10(A) - 10(N)) and a data analysis system. Each of the plurality of sensor devices (10(A) -10(N)) can include an environmental sensor to measure at least one parameter of an explosive event caused by an explosive device (410). Each sensor device can also include a time synchronization circuit to synchronize time stamping of the parameter measured by the environmental sensor, and a wireless communication interface. The data analysis system can access measurement data generated by the plurality of sensor devices (10(A) - 10(N)) and analyze the measurement data to produce a visualization mapping the measurements onto a virtual representation of the test environment (420).

Apparatus, system and method for medical analyses of seated individual

Apparatus, system and method for medical analysis of a seated individual, includes determining the aortic valve opening; the PTT; and calculating the PWV. Determining the aortic valve opening includes collecting BCG data while sitting on a seat and determining the timing of the aortic valve opening, taking into account posture. Measuring the aortic pulse wave transit time includes collecting BCG data while sitting on a seat capable of measuring changes in apparent weight; determining the timing of the aortic valve opening; detecting the arrival of the pulse wave at the end point; and measuring the relative timings of the two events. Calculating the PWV includes determining a length of the arterial segment through which a pulse wave is to be measured between a start point and an end point; and dividing the determined length of the arterial segment by the PTT.

Pulse wave velocity, arterial compliance, and blood pressure

Detecting and evaluating impact events

An impact detection device for detecting impacts to a body part of a user and various supporting systems are discussed. In an example, an impact detect device can include a circuit board, a component having a first section and a second section, a battery, and a molding for housing the circuit boat, the battery and the component. The circuit board can include impact detection circuitry including at least two sensors and a communication circuit. A zone of reduced rigidity can connect the first and second sections of the component, with the circuit board secured to the first section. The battery can be secured to the second section of the component allowing for flex relative to the circuit board. The molding can be shaped and dimensioned for mounting to a body part of the user.

Systems, devices and methods for health monitoring and identification of users

Systems, devices, and methods are disclosed herein for measuring sensor data of a user seated on a toilet and detecting/identifying the user based on the measured sensor data using statistical models and/or machine learning. In some embodiments, the systems described herein can include multiple sensors including force sensor(s), ECG sensor(s), PPG sensor(s), and other sensor(s), disposed in and/or integrated to a toilet. The sensors can measure and/or record sensor data including loads and forces, BCG-data, ECG-data, PPG data, bioimpedance, or the like, and determine, based on the sensor data, one or more physiological parameters and/or characteristics about the user. The systems can be further configured to associate the measured sensor data and the biological conditions and/or characteristics with a user identifier such that the user can be identified by comparing the user identifier with sensor data measured when a subject (e.g., an unknown subject) is seated on the toilet.

Leak-Free, Diffusion-Blocking Check Valve, Pump and Method

A closed leak-free, diffusion-blocking one-way check valve is composed of a substrate having a flow passage through the substrate, the flow passage has a sealing surface between the substrate and a membrane preventing flow through the flow passage. A thin film having internal stress is disposed on the membrane which induces deformation of the membrane biasing the membrane resulting in the sealing surface in a closed orientation. A method for fabrication and pump utilizing the check valve are disclosed.

Acoustic monitoring systems and methods

Systems and methods to provide acoustic monitoring are disclosed, comprising receiving a first acoustic signal and providing a first analog signal output representative of the received first acoustic signal using a first sensor, determining at least one of a continuous noise level of the first analog signal output of the first sensor or a peak level of impulse noise of the first analog signal output of the first sensor using analog signal processing circuitry, and sampling, using digital signal processing circuitry, at least one of the determined continuous noise level of the first analog signal output or the peak level of impulse noise of the first analog signal output from the analog signal processing circuitry to provide data privacy of the first analog signal output.

Blast sensor performance improvement

Systems and methods to reduce light transmission to a sensing element of a blast sensor are disclosed, including a light attenuation material to cover at least a portion of the blast sensor to reduce false detection of impulse noise or shock wave events by the sensing element of the blast sensor. The light attenuation material can include a pigmented gel having a specific pigment concentration and thickness to reduce false detection of events while maintaining performance of detection of impulse noise or shock wave events.

Leak-free, diffusion-blocking check valve, pump and method

A closed leak-free, diffusion-blocking one-way check valve is composed of a substrate having a flow passage through the substrate, the flow passage has a sealing surface between the substrate and a membrane preventing flow through the flow passage. A thin film having internal stress is disposed on the membrane which induces deformation of the membrane biasing the membrane resulting in the sealing surface in a closed orientation. A method for fabrication and pump utilizing the check valve are disclosed.